Fig. 8.
Inhibition of GDVII-induced cell death by anti-TRAIL and anti-TNF-R antibodies. Cells were infected, washed, and cultured for 24 h in the presence of either increasing concentrations of affinity-purified antibody or decreasing dilutions of antiserum. Caspase-3 activity was further determined as described under Materials and Methods. Negative controls were provided by normal rabbit serum (diluted 10−2) and normal purified goat IgG (10 μg/ml) (−). Results are given as mean percentage inhibition ± SD of infected cells based on absorbance at 405 nm in triplicate samples.