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. 2017 May 18;15(4):255–264. doi: 10.1016/S1875-5364(17)30042-0

Saposhnikoviae divaricata: a phytochemical, pharmacological, and pharmacokinetic review

Jenny Kreiner a, Edwin Pang b, George Binh Lenon a, Angela Wei Hong Yang a,*
PMCID: PMC7128302  PMID: 28527510

Abstract

Saposhnikoviae divaricata (Turcz.) Schischk (SD) is a traditional Chinese herb commonly used to treat clinical conditions such as rheumatism and allergic rhinitis. This review article evaluates a collection of works on in vitro and biochemical studies of SD. The discourse on the diverse class of chromones and coumarins in SD offers an insight to the pharmacological effects of these bioactive constituents as anti-inflammatory, analgesic, immunoregulatory, antioxidative, and anti-proliferative agents. It is highlighted that there is a structural relationship between the constituents and bioactive activities, which in effect provides a valid reasoning and reaffirm the use of SD in the treatment of the pathologies in Chinese medicine.

Key words: Saposhnikoviae divaricata, Chinese herbal medicine, Anti-inflammatory, Analgesic, Immunomodulatory, Anti-proliferative

Footnotes

All the authors have no conflicts of interest to declare.

Available online 20 Apr., 2017

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