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. 2006 Aug 24;40(3):133–138. doi: 10.1016/S1579-2129(06)70078-7

The Human Genome and Advances in Medicine: Limits and Future Prospects

A Pardo 1,*
PMCID: PMC7128613  PMID: 14998477

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REFERENCES

  • 1.Watson JD, Crick FHC. Molecular structure of nucleic acids. Nature. 1953;171:737–738. doi: 10.1038/171737a0. [DOI] [PubMed] [Google Scholar]
  • 2.Reddy VB, Thimmappaya B, Dhar R, Subramanian KN, Zain BS, Pan J. The genome of simian virus 40. Science. 1978;200:494–502. doi: 10.1126/science.205947. [DOI] [PubMed] [Google Scholar]
  • 3.Watson JD. The Human Genome Project: past, present, and future. Science. 1990;248:44–49. doi: 10.1126/science.2181665. [DOI] [PubMed] [Google Scholar]
  • 4.The International Human Genome Sequencing Consortium Initial sequencing and analysis of the human genome. Nature. 2001;409:860–921. doi: 10.1038/35057062. [DOI] [PubMed] [Google Scholar]
  • 5.Venter JC, Adams MD, Myers EW, Li PW Mural RJ, Sutton GG. The sequence of the human genome. Science. 2001;291:1304–1351. doi: 10.1126/science.1058040. [DOI] [PubMed] [Google Scholar]
  • 6.Coolins FS, Green ED, Guttmacher AE, Guter MS. A vision for the future of genomics research. A blueprint for the genomic era. Nature. 2003;422:835–847. doi: 10.1038/nature01626. [DOI] [PubMed] [Google Scholar]
  • 7.National Center for Biotechnology Information (NCBI) Human genome sequencing. Available at: http://www.ncbi.nlm.nih.gov/genome/seq/
  • 8.Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG. The genome sequence of Drosophila melanogaster. Science. 2000;287:2185–2195. doi: 10.1126/science.287.5461.2185. [DOI] [PubMed] [Google Scholar]
  • 9.Genome sequence of the rematode C. elegans: a platform for investigating biology. The C. elegans Sequencing Consortium. Science. 1998;282:2012–2018. doi: 10.1126/science.282.5396.2012. [DOI] [PubMed] [Google Scholar]
  • 10.Tabata S, Kaneko T, Nakamura Y, Kotani H, Kato T, Asamizu E. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Nature. 2000;408:823–826. doi: 10.1038/35048507. [DOI] [PubMed] [Google Scholar]
  • 11.Skaletsky H, Kuroda-Kawaguchi T, Minx PJ, Cordum HS, Hillier L, Brown LG. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. Nature. 2003;423:825–837. doi: 10.1038/nature01722. [DOI] [PubMed] [Google Scholar]
  • 12.Rozen S, Skaletsky H, Marszalek JD, Minx PJ, Cordum HS, Waterston RH. Abundant gene conversion between arms of palindromes in human and ape Y chromosomes. Nature. 2003;423:873–876. doi: 10.1038/nature01723. [DOI] [PubMed] [Google Scholar]
  • 13.Riordan JR, Rommens JM, Kerem B, Alon N, Rozmahel R, Grzelczak Z. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science. 1989;245:1066–1073. doi: 10.1126/science.2475911. [DOI] [PubMed] [Google Scholar]
  • 14.Ioannidis JP, Rosenberg PS, Goedert JJ, Ashton LJ, Benfield TL, Buchbinder SP. International meta-analysis of HIV host genetics. Effects of CCR5-Delta32, CCR2-64I, and SDF-1 3'A alleles on HIV-1 disease progression: an international meta-analysis of individual-patient data. Ann Intern Med. 2001;135:782–795. doi: 10.7326/0003-4819-135-9-200111060-00008. [DOI] [PubMed] [Google Scholar]
  • 15.NCBI Single nucleotide polymorphism. Available at: http://www.ncbi.nlm.nih.gov/SNP
  • 16.Available at: http://genome.gov/Pages/Research/HapMap
  • 17.National Human Genome Research Institute, Crick F. Central dogma of molecular biology. Nature. 1970;227:561–563. doi: 10.1038/227561a0. [DOI] [PubMed] [Google Scholar]
  • 18.Petricoin EF, III, Hackett JL, Lesko LJ, Puri RK, Gutman SI, Chumakov K. Medical applications of microarray technologies: a regulatory science perspective. Nat Genet. 2002;32(Suppl):474–479. doi: 10.1038/ng1029. [DOI] [PubMed] [Google Scholar]
  • 19.Busquets X, Agustí AGN. Chip genético (ADN array): el futuro ya está aquí. Arch Bronconeumol. 2001;37:394–396. doi: 10.1016/s0300-2896(01)78821-7. [DOI] [PubMed] [Google Scholar]
  • 20.Selman M. Clasificación actual de las neumonías intersticiales idiopáticas [editorial] Arch Bronconeumol. 2000;36:543–544. doi: 10.1016/s0300-2896(15)30094-6. [DOI] [PubMed] [Google Scholar]
  • 21.Zuo F, Kaminski N, Eugui E, Allard J, Yakhini Z, Ben-Dor A. Gene expression analysis reveals matrilysin as a key regulator of pulmonary fibrosis in mice and humans. Proc Natl Acad Sci USA. 2002;99:6292–6297. doi: 10.1073/pnas.092134099. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22.Sheppard D. Uses of expression microarrays in studies of pulmonary fibrosis, asthma, acute lung injury, and emphysema. Chest. 2002;121(3 Suppl):21S–25S. doi: 10.1378/chest.121.3_suppl.21s-a. [DOI] [PubMed] [Google Scholar]
  • 23.Pardo A, Smith KM, Abrams J, Coffman R, Bustos M, McClanahan TK. CCL18/DC-CK-1/PARC up-regulation in hypersensitivity pneumonitis. J Leukoc Biol. 2001;70:610–616. [PubMed] [Google Scholar]
  • 24.UNESCO Universal Declaration of the Human Genome and Human Rights. Available at: http://www.unesco.org/human_rights/hrbc.htm

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