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. 2016 Oct 31;14(10):721–731. doi: 10.1016/S1875-5364(16)30087-5

Photochemistry and pharmacology of 9, 19-cyclolanostane glycosides isolated from genus Cimicifuga

Yang SU a,b, Wen-Cheng CHI b,#, Lun WU b, Qiu-Hong WANG b,c, Hai-Xue KUANG b,*
PMCID: PMC7129281  PMID: 28236402

Abstract

The constituents of Cimicifuga plants have been extensively investigated, and the principal metabolites are 9, 19-cyclolanostane triterpenoid glycosides, which often exhibit extensive pharmacological activities. 9, 19-Cyclolanostane triterpenoid glycosides are distributed widely in genus Cimicifuga rather than in other members of the Ranunculaceae family. So far, more than 140 cycloartane triterpene glycosides have been isolated from Cimicifuga spp.. The aim of this review was to summarize all 9, 19-cyclolanostane triterpenoid glycosides based on the available relevant scientific literatures from 2000 to 2014. Biological studies of cycloartane triterpene glycosides from Cimicifuga spp. are also discussed.

Key words: Cimicifuga spp.; 9, 19-Cyclolanostane glycosides; Chemical structure; Biological effects

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Footnotes

Available online 20 Oct., 2016

[Research funding] This work was supported by National Natural Science Foundation of China (Nos. 81603416, 81274034), and by the Fund of Education Department of Heilongjiang Province, China (Nos.12541755, 12541752), and by the Natural Science Foundation of Heilongjiang Province (No. H201472)

These authors have no conflict of interest to declare.

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