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. 2008 Feb 13;109(1):21–27. doi: 10.1016/S0021-9975(08)80237-X

Neurotropism of mouse-adapted haemagglutinating encephalomyelitis virus

K Yagami a, Y Izumi a, N Kajiwara, F Sugiyama a, Y Sugiyama a
PMCID: PMC7130299  PMID: 8408778

Abstract

The propagation of a mouse-adapted strain, (67N) of haemagglutinating encephalomyelitis virus in infected mice and murine cells was examined by viral re-isolation and immunostaining. Viral propagation was strictly limited to the neurons and to an established line of neuroblastoma cells in in-vivo and in-vitro experiments. These results provide adequate evidence that this virus is neurotropic.

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