Skip to main content
PMC home page
Elsevier - PMC COVID-19 Collection logoLink to Elsevier - PMC COVID-19 Collection
. 2004 Feb 9;169(1):217–221. doi: 10.1016/0042-6822(89)90058-5

Phylogeny of antigenic variants of avian coronavirus IBV☆

JG Kusters ∗,†,‡,1, HGM Niesters †,2, JA Lenstra ∗, MC Horzinek †, BAM van der Zeijst ∗
PMCID: PMC7131080  PMID: 2466369

Abstract

The sequences of the peplomeric S1 protein of four serologically distinct strains of the infectious bronchitis virus (IBV), an avian coronavirus, have been determined. The S1 protein is thought to contain the serotype-specific neutralization epitopes and to be the main target of antigenic variation. An alignment with sequences of three strains published previously showed that from the 545 amino acid residues only 243 have been conserved. Clustering of substitutions suggests that most serotype determinants are located within the first 300 amino acid residues of S1. A phylogenetic tree of the S1 sequences showed very variable rates of divergence. Differences in topology with a tree based on RNAse-T1 fingerprint data indicate that some of the IBV strains have arisen by genetic recombination.

Footnotes

☆

Sequence data from this article have been deposited with the EMBL/GenBank Data Libraries under Accession No. J04329.

References

  • 1.Aaronson R.P., Young J.F., Palese P. Nucleic Acids Res. 1982;10:237–246. doi: 10.1093/nar/10.1.237. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Beck E., Feil G., Strohmayer K. EMBO J. 1983;2:555–559. doi: 10.1002/j.1460-2075.1983.tb01462.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Binns M.M., Boursnell M.E.G., Cavanagh D., Pappin D.J.C., Brown T.D.K. J. Gen. Virol. 1985;66:719–726. doi: 10.1099/0022-1317-66-4-719. [DOI] [PubMed] [Google Scholar]
  • 4.Binns M.M., Boursnell M.E.G., Tomley F.M., Brown T.D.K. J. Gen. Virol. 1986;67:2825–2831. doi: 10.1099/0022-1317-67-12-2825. [DOI] [PubMed] [Google Scholar]
  • 5.Cavanagh D., Darbyshire J.H., Davis P., Peters R.W. Avian Pathol. 1984;13:573–583. doi: 10.1080/03079458408418556. [DOI] [PubMed] [Google Scholar]
  • 6.Cavanagh D., Davis P.J., Pappin D.J.C., Binns M.M., Boursnell M.E.G., Brown T.D.K. Virus Res. 1986;4:133–143. doi: 10.1016/0168-1702(86)90037-7. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Cavanagh D., Davis P.J., Darbyshire J.H., Peters R.W. J. Gen. Virol. 1986;67:1435–1442. doi: 10.1099/0022-1317-67-7-1435. [DOI] [PubMed] [Google Scholar]
  • 8.Cavanagh D., Davis P.J. J. Gen. Virol. 1988;69:621–629. doi: 10.1099/0022-1317-69-3-621. [DOI] [PubMed] [Google Scholar]
  • 9.Cavanagh D., Davis P.J., Mockett A.P.A. Virus Res. 1988;11:141–150. doi: 10.1016/0168-1702(88)90039-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Cook J.K.A. Avian Pathol. 1984;13:733–741. doi: 10.1080/03079458408418570. [DOI] [PubMed] [Google Scholar]
  • 11.Cheung A., Delmartes J., Weiss S., Küpper H. J. Virol. 1983;48:451–459. doi: 10.1128/jvi.48.2.451-459.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 12.Clewley J.P., Morser J., Avery R.J., Lomniczi B. Infect. Immunol. 1981;32:1227–1233. doi: 10.1128/iai.32.3.1227-1233.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Davelaar F.G., Kouwenhoven B., Burger A.G. Vet. 0. 1984;6:114–120. doi: 10.1080/01652176.1984.9693924. [DOI] [PubMed] [Google Scholar]
  • 14.de Groot R.J., Luytjes W., Horzinek M.C., van der Zeijst B.A.M., Spaan W.J.M., Lenstra J.A. J. Mol. Biol. 1987;196:963–966. doi: 10.1016/0022-2836(87)90422-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 15.Felsenstein J. Evolution. 1985;39:783–791. doi: 10.1111/j.1558-5646.1985.tb00420.x. [DOI] [PubMed] [Google Scholar]
  • 16.Green K.Y., Midthun K., Gorziglia M., Hoshino Y., Kapikian A.Z., Chanock R.M., Flores J. Virology. 1987;161:153–159. doi: 10.1016/0042-6822(87)90181-4. [DOI] [PubMed] [Google Scholar]
  • 17.Gunn P.R., Sato F., Powell K.F.H., Bellamy A.R., Napier J.R., Harding D.R.K., Hancock W.S., Siegman L.J., Both G.W. J. Virol. 1985;54:791–797. doi: 10.1128/jvi.54.3.791-797.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18.Holland J., Spindler K., Horodyski F., Grabau E., Nichol S., Vandepol S. Science. 1982;215:1577–1585. doi: 10.1126/science.7041255. [DOI] [PubMed] [Google Scholar]
  • 19.Keck J.G., Stohlman S.A., Soe L.H., Making S., Lai M.M.C. Virology. 1987;156:331–341. doi: 10.1016/0042-6822(87)90413-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20.Kewk J.G., Matsushima G.K., Making S., Fleming J.0., Vannier D.M., Stohlman S.A., Lai M.C. J. Virol. 1988;62:1810–1813. doi: 10.1128/jvi.62.5.1810-1813.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Kew 0.M., Nottay B.K. Modern Approaches to Vaccines. In: Chanock R., Lerner R., editors. Cold Spring Harbor Laboratory; Cold Spring Harbor, NY: 1984. pp. 357–362. [Google Scholar]
  • 22.King A.M.Q., McCahon D., Slade W.R., Newham J.W.I. Cell. 1982;29:921–928. doi: 10.1016/0092-8674(82)90454-8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23.Kirkegaard K., Baltimore D. Cell. 1986;47:433–443. doi: 10.1016/0092-8674(86)90600-8. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 24.Kusters J.G., Niesters H.G.M., Bleumink-Pluym N.M.C., Davelaar F.G., Horzinek M.C., Van der Zeiist B.A.M. J. Gen. Virol. 1987;68:343–352. doi: 10.1099/0022-1317-68-2-343. [DOI] [PubMed] [Google Scholar]
  • 25.Lenstra J.A., Kusters J.G., Koch G., van der Zeijst B.A.M. Mol. Immunol. 1989;26:7–15. doi: 10.1016/0161-5890(89)90014-X. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 26.Making S., Keck J.G., Stohlman S.A., Lai M.M.C. J. Virol. 1986;57:729–737. doi: 10.1128/jvi.57.3.729-737.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 27.Making S., Fleming J.0., Keck J.G., Stohlman S.A., Lai M.M.C. 2nd ed. Vol. 84. 1987. pp. 6567–6571. (Proc. Natl. Acad. Sci. USA). [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 28.McCahon D., Slade W.R., Priston K.A.J., Lake J.R. J. Gen. Virol. 1977;35:555–565. doi: 10.1099/0022-1317-35-3-555. [DOI] [PubMed] [Google Scholar]
  • 29.Mockett A.P.A., Cavanagh D., Brown T.D.K. J. Gen. Virol. 1984;65:2281–2286. doi: 10.1099/0022-1317-65-12-2281. [DOI] [PubMed] [Google Scholar]
  • 30.Modrow S., Hahn B.H., Shaw G.M., Gallo R.C., Wongstaal F., Wolf H. J. Virol. 1986;61:570–578. doi: 10.1128/jvi.61.2.570-578.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 31.Niesters H.G.M., Lenstra J.A., Spaan W.J.M., Zudderveld A.J., Bleumink-Pluym N.M.C., Hong F., van Scharrenburg G.J.M., Horzinek M.C., van der Zeijst B.A.M. Virus Res. 1986;5:253–263. doi: 10.1016/0168-1702(86)90022-5. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 32.Romanova L.I., Tolskaya E.A., Kolesnikova M.S., Agol V.I. FEBS Lett. 1980;118:109–112. doi: 10.1016/0014-5793(80)81229-4. [DOI] [PubMed] [Google Scholar]
  • 33.Steinhauer D.A., Holland J.J. J. Virol. 1986;57:219–228. doi: 10.1128/jvi.57.1.219-228.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 34.Stern D.F., Sefton B.M. J. Virol. 1982;44:794–803. doi: 10.1128/jvi.44.3.794-803.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 35.Wege H., Siddell S., Ter Mellen V. Curr. Top. Microbiol. Immunol. 1982;99:165–200. doi: 10.1007/978-3-642-68528-6_5. [DOI] [PubMed] [Google Scholar]

Articles from Virology are provided here courtesy of Elsevier

RESOURCES