Scientific Abstract Sessions

Poster Session

2201

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Asthma Therapy I

1   Paradoxical Bronchospasm With a Near-Fatal Reaction to Albuterol-HFA and Levalbuterol inhalation solution leading to Intubation in an Adult Asthmatic

S. Amara, N. Gupta, B. Silverman, Y. A. K. Rao, A. T. Schneider; Long Island College Hospital, Brooklyn, NY.

2   Gata-3-specific Dnazyme As An Appraoch For Asthma-therapy

T. Dicke, M. Wegmann, S. Sel, H. Renz, H. Garn; Medical Faculty, Philipps University, Marburg, GERMANY.

3   Bronchial Thermoplasty in Refractory Asthma: Interim Results in a Severe Asthma Population (Research in Severe Asthma (RISA) Trial)

R. Niven ¹, I. Pavord², M. Laviolette³, N. Thomson⁴, P. Corris⁵, G. Cox⁶, K. Fan-Chung⁷, A. Sperb-Rubin⁸; ¹South Manchester University Hospitals NHS Trust, Manchester, UNITED KINGDOM, ²Glenfield General Hospital, University of Leicester, Leicester, UNITED KINGDOM, ³Laval University, Sainte-Foy, PQ, CANADA, ⁴Gartnaval General Hospital, Glasgow, UNITED KINGDOM, ⁵Freeman Hospital, Newcastle upon Tyne, UNITED KINGDOM, ⁶McMaster University, Hamilton, ON, CANADA, ⁷NHLI-Royal Brompton, London, UNITED KINGDOM, ⁸Irmandade Santa Casa de Misericordia, Porto Alegre, BRAZIL.

4   Compatability of Levalbuterol Inhalation Solution Mixed with Budesonide, Ipratropium Bromide, Cromolyn Sodium or Acetylcysteine Sodium

W. K. McVicar, P. Bonasia, S. Ong; Sepracor Inc., Marlborough, MA.

5   A Comparison of Bronchodilator Expressions to Identify the Asthmatic Child

S. P. Galant ^1,2, T. Morphew³, S. Amaro^1,4, O. Liao^1,5; ¹Children's Hospital of Orange County, Orange, CA, ²Southern California Chapter of Asthma and Allergy Foundation of America (AAFA), Los Angeles, CA, ³Southern California Chapter of Asthma and Allergy Foundation of America (AAFA), Los Anges, CA, ⁴Breathmobile TM Orange County, Orange, CA, ⁵Breathmboile TM Orange County, Orange, CA.

6   Adrenergic β2 Receptor Genotyping in Asthma: Case Reports

S. E. Leonard; Virginia Commonwealth University, Richmond, VA.

7   Effect of Budesonide and Formoterol Administered Via One Pressurized Metered-dose Inhaler on Lung Function in Adults and Adolescents With Moderate to Severe Persistent Asthma

M. J. Noonan ¹, L. J. Rosenwasser², P. Martin³, C. D. O'Brien³, L. O'Dowd³; ¹Allergy Associates Research Center, Portland, OR, ²Children's Mercy Hospital, Kansas City, MO, ³AstraZeneca, Wilmington, DE.

8   Efficacy and Safety of Intravenous Aminophylline in Children with Acute Exacerbation of Asthma: A Multicenter Randomized Trial

M. Nagao ^1,2, T. Katsunuma^3,2, C. K. Kim^4,2, T. Fujisawa^1,2; ¹Mie National Hospital, Tsu, JAPAN, ²Mie-Jikei-Inje theophylline study group, Tsu, JAPAN, ³Jikei University, Tokyo, JAPAN, ⁴University, Seoul, REPUBLIC OF KOREA.

9   Funtional Role Of Glucocorticoid Receptor β In The Steroid-induced Suppression Of Il-8 In Airway Epithelial Cells

Y. Jee ¹, J. Park¹, Y. Kim¹, M. Kim², Y. Cho², P. Lavender³; ¹College of Medicine, Dankook university, Cheonan, REPUBLIC OF KOREA, ²College of Medicine, Ewha Woman's university, Seoul, REPUBLIC OF KOREA, ³King's College, London, UNITED KINGDOM.

10   Development of Asthma Study Technologies in an Environmental Chamber (ASTEC)

A. Salapatek ^1,2, P. Patel¹, N. Mec¹, L. Nimraj¹, A. Ramoutar¹, M. D. Chapman³, J. D. Freihaut⁴; ¹Allied Research International, Mississauga, ON, CANADA, ²Centre of Mathematics and Medicine, Fields Institute, Toronto, ON, CANADA, ³INDOOR Biotechnologies Inc., Charlottesville, VA, ⁴Pennsylvania State University, University Park, PA.

11   Cutaneous CpG Administration Reduces Th2-type Airway Inflammation But Induces Airway Hyperreactivity

R. Haapakoski ¹, N. Fyhrquist-Vanni¹, T. Savinko¹, H. Wolff², K. Turjanmaa³, T. Palosuo⁴, T. Reunala³, A. Lauerma⁵, H. Alenius¹; ¹Unit of Excellence in Immunotoxicology, Finnish Institute of Occupational Health, Helsinki, FINLAND, ²Team for Biological Mechanisms and Prevention of Work-related Diseases, Finnish Institute of Occupational Health and Department of Pathology, Helsinki University Central Hospital, Helsinki, FINLAND, ³Department of Dermatology, Tampere University and University Hospital, Tampere, FINLAND, ⁴Laboratory of Immunobiology, National Public Health Institute, Helsinki, FINLAND, ⁵Control of Hypersensitivity Diseases, Finnish Institute of Occupational Health, Helsinki, FINLAND.

12   New Treatments for Suppression of Ongoing Human and Murine IgE Responses

H. G. Durkin, T. A. Smith-Norowitz, M. Pincus, M. Nowakowski, M. H. Bluth, R. Joks; Center for Allergy and Asthma Research, SUNY Downstate, Brooklyn, NY.

13   Formoterol Treatment plus Tiotropium Results in Greater Improvements in Lung Function Compared with Tiotropium Administered Alone in Patients with COPD

D. Tashkin ¹, S. Varghese²; ¹David Geffen School of Medicine, Los Angeles, CA, ²Schering-Plough, Kenilworth, NJ.

14   Montelukast Added to Usual Therapy during the September Epidemic of Asthma Exacerbations in Children

N. W. Johnston, P. J. Mandhane, J. Dai, J. M. Duncan, J. M. Greene, K. Lambert, M. R. Sears; Firestone Institute for Respiratory Health, Hamilton, ON, CANADA.

15   Addition of Omalizumab Improves Quality of Life in Moderate-Severe Asthmatics Receiving Fluticasone 500 μg/Salmeterol 50 μg

M. Massanari, R. J. Maykut, F. Kianifard, R. K. Zeldin, G. P. Geba; Novartis Pharmaceuticals Corporation, East Hanover, NJ.

16   Effects Of MN-001 In Patients With Mild-to-moderate Asthma In A Randomized, Double-blind And Placebo-controlled Phase II Study

W. W. Busse ¹, H. S. Nelson², P. E. Korenblat³, M. J. Noonan⁴, K. W. Locke⁵, M. S. Munsey⁵, R. E. Gammans⁵; ¹University of Wisconsin, Madison, WI, ²National Jewish Medical Research Center, Denver, CO, ³Associated Specialists In Internal Medicine, St. Louis, MO, ⁴Allergy Associates Research Center, Portland, OR, ⁵MediciNova, Inc., San Diego, CA.

17   Safety of Budesonide and Formoterol Administered Via One Pressurized Metered-dose Inhaler (Budesonide/Formoterol pMDI) in Patients (≥2 Years) With Moderate to Severe Persistent Asthma

L. J. Rosenwasser ¹, M. J. Noonan², P. Martin³, L. O'Dowd³, C. D. O'Brien³; ¹Children's Mercy Hospital, Kansas City, MO, ²Allergy Associates Research Center, Portland, OR, ³AstraZeneca, Wilmington, DE.

18   The Effects of Mometasone DPI on Airway Hyperresponsiveness and Markers of Airway Inflammation

F. A. Romero, V. Mehta, A. I. Berro, J. Stokes, T. B. Casale; Creighton University, Omaha, NE.

19   Objective evidence of omalizumab treatment assessed by Forced Oscillation (FO)

C. Saadeh, M. D. Goldman, C. K. Saadeh, J. R. Lemert, Jr.; Amarillo Center for Clinical Research, Amarillo, TX.

20   Saccharomyces (S.) Cerevisiae Mannan Facilitates Airway Epithelial Repair

C. F. Michael, K. Chapman, B. Lew, C. Waters; UT Health Science Center, Memphis, Memphis, TN.

21   Streptomyces cerevisiae 1,3/1,6 Beta-glucan Prevents Airway Hyperreactivity and Pulmonary Inflammation in a Murine Asthma Model

M. Oh ¹, T. Zhang¹, R. Seljelid², X. Li¹; ¹Mt. Sinai School of Medicine, New York, NY, ²University of Tromso, Tromso, NORWAY.

22   The Effect of Discontinuing Omalizumab Therapy on Free IgE Concentration

P. Lowe ¹, J. Jaffe², C. Martin³, L. Brookman³, H. Fox³; ¹Novartis Pharmaceuticals AG, Basel, SWITZERLAND, ²Novartis Pharmaceuticals Corporation, East Hanover, NJ, ³Novartis Horsham Research Centre, Horsham, UNITED KINGDOM.

Poster Session

2202

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Asthma Control

23   Quality of Life of Caregivers of Underserved Children with Asthma

D. Sztein ¹, M. Streett², M. Foster³, C. Vibbert², T. Morphew⁴, M. E. Bollinger²; ¹Haverford College, Philadelphia, PA, ²University of Maryland School of Medicine, Baltimore, MD, ³University of Maryland Hospital for Children, Baltimore, MD, ⁴Southern CA Asthma and Allergy Foundation, Los Angeles, CA.

24   Asthma Control Test: reliability, validity, and responsiveness in Korean patients

K. Hyouk-Soo ^1,2, K. Deok-In^1,2, P. Chang-Han^1,2, S. Seong-Wook^1,2, L. Sang-Min^1,2, S. Woo-Jung^1,2, K. Yong-Eun³, P. Heung-Woo^1,2, K. Sun-Sin^1,2, C. Sang-Heon^1,2, M. Kyoung-Up^1,2, K. You-Young^1,2, C. Yoon-Seok^1,4; ¹Department of Internal Medicine, Seoul National University College of Medicine, Seoul, REPUBLIC OF KOREA, ²Instutute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, REPUBLIC OF KOREA, ³Department of Internal Medicine, Chosun University College of Medicine, Gwangju, REPUBLIC OF KOREA, ⁴Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, REPUBLIC OF KOREA.

25   Self Reported Provider Adherence to NAEPP Guidelines for Control of Factors Contributing to Asthma Severity

P. J. Warrier ¹, S. Dever¹, M. Shah², D. M. O'Sullivan³, J. E. Thomas¹; ¹Hartford Hospital, University of Connecticut, Hartford, CT, ²Bridgeport Hospital, Bridgeport, CT, ³Hartford Hospital, Hartford, CT.

26   Race, Asthma Exacerbations and Leaving against Medical Advice

B. D. Tano; University of Texas Health Center at Tyler, Tyler, TX.

27   Use of a Validated Asthma Symptom Questionnaire to Predict Obstructive Flow Volume Loop in School-Aged Children

M. Michelis, J. F. Hirsh, A. Oughourli, D. J. Lee; Hackensack University Medical Center, Hackensack, NJ.

28   Real-World Evaluation of Asthma Control and Treatment (REACT): Findings from a National Web-Based Survey

S. P. Peters ¹, C. A. Jones², T. Haselkorn³, D. R. Mink⁴, D. J. Valacer³, S. T. Weiss⁵; ¹Wake Forest University School of Medicine, Winston-Salem, NC, ²University of Southern California Medical Center, Los Angeles, CA, ³Genentech, Inc., South San Francisco, CA, ⁴Ovation Research Group, San Francisco, CA, ⁵Brigham & Women's Hospital, Harvard Medical School, Boston, MA.

29   Keeping Asthmatics Out of the Emergency Department and Hospital: Evidence for Asthma Controller Medication Usage for Intermittent Asthmatics

C. C. Spagnola ¹, W. W. Crawford², M. Schatz³, R. K. Nakahiro⁴; ¹Southern California Permanente Medical Group, Los Angeles, CA, ²Southern California Permanente Medical Group, Harbor City, CA, ³Southern California Permanente Medical Group, San Diego, CA, ⁴Kaiser Permanente Medical Care Program, Los Angeles, CA.

30   Childhood Asthma Control Test: Reliability, Validity And Responsiveness

R. Jan ^1,2, I. Liu¹, S. Chen¹, C. Shieh³, J. Wang¹; ¹Dept of Ped, College of Medicine, National Cheng Kung University, Tainan, TAIWAN, ²Dept of Ped,College of Medicine, National Cheng Kung University, Tainan, TAIWAN, ³Dept of Microbiology and Immunology, College of Medicine, National Cheng Kung University, Tainan, TAIWAN.

31   Achieving and Maintaining Control of Asthma with Regular Participation in an Urban Pediatric Disease Management Program: The Breathmobile® Program

C. A. Jones ¹, L. T. Clement², T. Morphew³, J. Hanley-Lopez¹, K. Y. C. Kwong¹, F. Lifson³, L. Opas¹, J. J. Guterman⁴; ¹Los Angeles County + University of Southern California Medical Center and the Keck School of Medicine at the University of Southern California, Los Angeles, CA, ²University of South Alabama College of Medicine, Mobile, AL, ³Southern California Chapter of the Asthma and Allergy Foundation of America, Los Angeles, CA, ⁴Los Angeles County Department of Health Services, Olive-View UCLA Medical Center and the Geffin School of Medicine at the University of California at Los Angeles, Los Angeles, CA.

32   Implementation of GINA Guidelines in Poor Countries May Have Resulted in an Unnecessary Expenditure on Pharmacotherapy

J. E. Gereda; Clinica Ricardo Palma, Lima, PERU.

33   No Correlation Between Airway Obstruction Measured by FEV₃/FVC and Asthma Control Test Scores

E. C. Swartz, M. K. Bossard, K. McCarthy, R. López, D. M. Lang; Cleveland Clinic, Cleveland, OH.

34   Does A Www-based Interactive Computer Program change asthma Outcomes, Quality of Life and Asthma Knowledge

U. M. Andersen ^1,2; ¹Aalborg Sygehus Nord, Aalborg, DENMARK, ²Pediatric Department, Aalborg Sygehus Nord, Aalborg, DENMARK.

35   Update on the Effect of a Multidisciplinary Team Clinic on Asthma Outcome for Medicaid-Eligible Inner City Children with Moderate to High-Risk Asthma

P. P. Patel, P. Munzenberger, R. Marocco, S. Taormina, W. Alame, J. Montejo, M. Pansare, E. A. Secord; Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan-Wayne State University, DETROIT, MI.

36   Effect of Omalizumab on Measures of Control in Adolescents with Moderate-Severe Persistent Asthma

S. J. Pollard ¹, R. J. Maykut², M. Massanari², F. Kianifard², R. K. Zeldin², G. P. Geba²; ¹Family Allergy and Asthma, Louisville, KY, ²Novartis Pharmaceuticals Corporation, East Hanover, NJ.

37   Assessment of Asthma Control in a United States Population

M. Blaiss¹, R. Manjunath ², A. Dalal², P. Jhingran²; ¹Allergy and Asthma Care, Germantown, TN, ²GlaxoSmithKline, RTP, NC.

38   Risk Factors for Asthma-Related Emergency Hospital Utilization Differ Between High and Low Users of Asthma Medications

R. T. Hsu ¹, W. W. Crawford², W. B. Klaustermeyer¹, M. Schatz³; ¹VA Greater Los Angeles Healthcare System, Los Angeles, CA, ²Kaiser Permanente, Southern California, Harbor City Medical Center, CA, ³Kaiser Permanente, Southern California, San Diego Medical Center, CA.

39   Change (Δ) in Percent Forced Expiratory Volume in the First Second (FEV1) in 10 patients on Omalizumab Over 23 Months

K. Shamir, A. Hersh, H. Aguila, J. Pepe, A. Wolff, L. Bielory; UMDNJ Medical School, Newark, NJ.

40   Pulmonary Function Test Values Predictive of Success in Decreasing Inhaled Corticosteroid Doses in Asthmatics: A Chart Review

L. M. Miller ¹, M. V. White²; ¹Washington Hospital Center, Washington, DC, ²Institute for Asthma & Allergy, Wheaton, MD.

Poster Session

2203

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Immunodeficiency Diseases I

41   Evaluation and Standardization of Enzyme-Linked ImmunoSpot (ELISPOT) Assay for Measurement of Pathogen-Specific T-cell Responses in Normal Donors

G. V. Yamshchikov, J. A. Franklin, C. D. Williams, L. K. Wathen, J. F. Halsey; IBT Reference Laboratory, Lenexa, KS.

42   Comèl-Netherton Syndrome - New Insight Into The Molecular Basis of this Rare Syndrome Characterized by Atopic Diathesis and Immune Deficiency

E. D. Renner ^1,2, S. Rylaarsdam¹, S. Anover¹, D. Hartl², A. Jayakumar³, B. H. Belohradsky², U. Ermer⁴, Y. Jin¹, G. Kleiner⁵, F. Nagel², Q. Zhu¹, G. L. Claymann³, T. R. Torgerson¹, H. D. Ochs¹; ¹University of Washington, Seattle, WA, ²Dr. v. Haunersches Kinderspital, Ludwig Maximilian University, Munich, GERMANY, ³The University of Texas M. D. Anderson Cancer Center, Houston, TX, ⁴Children's Hospital, Neuburg, GERMANY, ⁵University of Miami Bachelor Children's Research Center, Miami, FL.

43   European Consensus for Gynecologycal and Obstetric Management of Women with Hereditary Angioedema due to C1-Inhibitor Deficiency (HAE): PREHAEAT

T. Caballero ^1,2, L. Bouillet^3,4, K. Bork^5,6, C. Bucher^7,8, A. Bygum^9,10, C. De Carolis^11,12, H. Farkas^13,14, H. Longhurst^15,16, E. Nielsen^17,18, R. Perricone^19,12, N. Prior¹, M. Cicardi^20,21; ¹University Hospital La Paz, Madrid, SPAIN, ²PREHAEAT Member, Coordinator of Consensus, Madrid, SPAIN, ³Grenoble University Hospital, Grenoble, FRANCE, ⁴PREHAEAT Member, Coordinator Work Package 5, Grenoble, FRANCE, ⁵Johannes-Gutenberg-University of Mainz, Mainz, GERMANY, ⁶PREHAEAT Member (alphabetic order), Mainz, GERMANY, ⁷University of Zurich, Zurich, SWITZERLAND, ⁸PREHAEAT Member (alphabetic order), Zurich, SWITZERLAND, ⁹Odense University Hospital, Odense C, DENMARK, ¹⁰PREHAEAT Member (alphabetic order), Odense, DENMARK, ¹¹San Giacomo Hospital, Rome, ITALY, ¹²PREHAEAT Member (alphabetic order), Rome, ITALY, ¹³Semmelweis University, Budapest, HUNGARY, ¹⁴PREHAEAT Member (alphabetic order), Budapest, HUNGARY, ¹⁵Barts and the London NHS Trust, London, UNITED KINGDOM, ¹⁶PREHAEAT Member (alphabetic order), London, UNITED KINGDOM, ¹⁷Norland Hospital and University of Tronsø, Bodø, NORWAY, ¹⁸PREHAEAT Member (alphabetic order), Bodø, NORWAY, ¹⁹PTV and University of Rome “Tor Vergata”, Rome, ITALY, ²⁰Università degli Studi de milano; Ospedale S. Giuseppe, Milan, ITALY, ²¹Coordinator of PREHAEAT Group, Milan, ITALY.

44   Tolerance To Allogeneic Thymus Transplantation In Complete DiGeorge Syndrome

I. K. Chinn, B. H. Devlin, M. J. Alexieff, J. Li, S. E. Gupton, E. A. McCarthy, M. L. Markert; Duke University Medical Center, Durham, NC.

45   Development Of A Newborn Screening Test For Severe Combined Immunodeficiency Using ELISA And Dried Blood Spots

K. Chen, S. A. McGhee, E. R. B. McCabe; David Geffen School of Medicine at UCLA, Los Angeles, CA.

46   Use of Wiskostatin to Recapitulate the Wiskott-Aldrich Syndrome Phenotype in-vitro

S. Roy-Ghanta, E. P. Williams, R. P. Deering, J. S. Orange; University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA.

47   Defective Pneumococcal Polysaccarides-induced Cytokine Production in Common Variable Immunodeficiency

R. Hong, S. Gupta; University of California, Irvine, CA.

48   Helicobacter Pylori Infection As A Triggering Factor Of Attacks In Patients With Hereditary Angioedema

B. Visy ¹, G. Füst², A. Bygum³, K. Bork⁴, H. J. Longhurst⁵, C. Bucher⁶, L. Bouillet⁷, M. Cicardi⁸, H. Farkas²; ¹Madarász street Hospital of Heim Pál' Pediatric Hospital, Budapest, HUNGARY, ²Semmelweis University, Budapest, HUNGARY, ³Odense University Hospital, Odense, DENMARK, ⁴Johannes Gutenberg University, Mainz, GERMANY, ⁵Barts and the London NHS Trust, London, UNITED KINGDOM, ⁶University Hospital, Zurich, SWITZERLAND, ⁷CHU de Grenoble, Grenoble, FRANCE, ⁸Università degli Studi di Milano, Milan, ITALY.

49   Genetic Analysis of Autosomal Dominant Common Variable Immunodeficiency

A. Marks ¹, H. Meyerson¹, B. Grimbacher², R. W. Hostoffer, Jr.¹; ¹Case Western Reserve University, Cleveland, OH, ²University Of Friedburg, Friedburg, GERMANY.

50   Role of Toll-like Receptor Signalling Defects in Human Susceptibility to Invasive Infection by Streptococcus Pneumoniae

S. E. Turvey ¹, A. F. Hirschfeld¹, R. E. Victor¹, J. S. Orange², J. A. Bettinger¹; ¹BC Children's Hospital and University of British Columbia, Vancouver, BC, CANADA, ²Children's Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA.

51   Guidelines for “10 Warning Signs of Primary Immunodeficiency” Neither Sensitive Nor Specific

F. P. Aloi, S. S. Mishra, A. J. MacGinnitie; Children's Hospital of Pittsburgh, Pittsburgh, PA.

52   Reimbursement Driven Medicare Patients Receiving IVIgG in the Hospital vs. the Physician's Office

M. Eagam ¹, R. W. Hostoffer, Jr.²; ¹Lake Erie College of Osteopathic Medicine, Erie, PA, ²Case Western Reserve University, Cleveland, OH.

53   Hypo-IgM Syndrome: A Secretion Defect?

S. P. Silverman, D. W. Rosenthal, P. Ponda, V. R. Bonagura; North Shore-Long Island Jewish Medical Center, Great Neck, NY.

54   Allergic Reaction and Anaphylaxis to IVIg when Administered Through Bromobutyl Vial Closure

M. Solomon, R. W. Hostoffer, Jr.; Case Western Reserve University, Cleveland, OH.

55   NEMO (IKKγ) Mutation Can Be Associated With Opportunistic Infection Without Impairing TLR Function

E. W. Gelfand ¹, B. Salt¹, A. Jain², J. E. Niemela², R. Deering³, R. Pandey³, R. Quinones⁴, J. Orange³; ¹National Jewish Medical and Research Center, Denver, CO, ²National Institutes of Health, Bethesda, MD, ³Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Children's Hospital of Denver, Denver, CO.

56   Primary Immunodeficiency Disorders: 30 Years of Experience in Shanghai, China

T. Chen, D. Ying; Shanghai Jiao Tong University School of Medicine, Shanghai, CHINA.

57   Antibody Deficiency Disorders in Recurrent/persistent pneumonia and Chronic Sinusitis in Thai Children at Queen Sirikit National Institute of Child Health.

P. Lerdluedeeporn, IV ¹, C. Thanee², N. Pupugdee², S. Nanthapisal², G. Phongsamart², M. Vangveeravong²; ¹Bangkok International Hospital, Bangkok, THAILAND, ²Queen Sirikit National Intitute of Child Health, Bangkok, THAILAND.

58   Subcutaneous Bioavailability of Gamunex® in Rabbits

M. Pamarthi, G. Taylor, P. Scuderi, V. Arora; Talecris Biotherapeutics, Research Triangle Park, NC.

59   Infants With Decreased Immunoglobulin Levels

S. J. McGeady, S. Kung; Thomas Jefferson University, Philadelphia, PA.

60   Idiopathic CD4+ T-Lymphocytopenia (ICL) in a Child with Persistent Cryptococcal Meningitis

Y. Yilmaz¹, B. Wilson², M. Lowery-Nordberg³, J. A. Bocchini, Jr.⁴, S. L. Bahna ²; ¹Department of Pediatrics, Louisiana State University Health Sciences Center, Shreveport, LA, ²Allergy/Immunology Section, Louisiana State University Health Sciences Center, Shreveport, LA, ³Department of Pathology, Louisiana State University Health Sciences Center, Shreveport, LA, ⁴Pediatric Infectious Disease Section, Louisiana State University Health Sciences Center, Shreveport, LA.

61   Novel CYBA Gene Mutation in a Patient with Chronic Granulomatous Disease Associated with Autoimmune Hepatitis

A. Bagg ¹, R. Gonzalez-Peralta², A. Petrovic³, J. W. Sleasman⁴; ¹Division of Allergy and Immunology, James A Haley Veterans Hospital, Tampa, FL, ²University of Florida Pediatric Gastroenterology, Gainesville, FL, ³Department of Pediatrics, University of South Florida College of Medicine, St. Petersburg, FL, ⁴Department of Pediatrics, Division of Allergy and Immunology, University of South Florida College of Medicine, St. Petersburg, FL.

62   Mannose-Binding Lectin Deficiency in a Family with Frequent Respiratory Infections

W. Zheng ^1,2, J. Hester³, C. Kirkpatrick²; ¹National Jewish Medical and Research Center, Denver, CO, ²University of Colorado Health Sciences Center, Denver, CO, ³IBT Reference Laboratory, Lenexa, KS.

63   Pediatric Patients With Refractory Autoimmune Cytopenias Displaying Autoimmune Lymphoproliferative Syndrome (ALPS) Phenotypes - Role For Anti-cd20(Rituximab ™) Therapy

T. Chang, D. Schauer, W. Grossman; Medical College of Wisconsin, Milwaukee, WI.

Poster Session

2204

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Autoimmunity

64   β-tubulin Induced Murine Model of Autoimmune Hearing Loss and Regulation of T Cell Cytokines of the Mice

S. H. Cho, B. Zhou, J. Glickstein, M. H. Kermany, C. Cai, Q. Cai, W. Liu, T. J. Yoo; University of Tennessee Health Science Center, Memphis, TN.

65   The Clinical Significance Of Isolated Antinucleolar Antibodies

S. Khan ¹, S. Holding², A. Alvi³, S. Saravana⁴, W. A. C. Sewell^1,5; ¹Scunthorpe General Hospital, Scunthorpe, UNITED KINGDOM, ²Hull Royal Infirmary, Hull, UNITED KINGDOM, ³Diana Princess of Wales Hospital, Grimsby, UNITED KINGDOM, ⁴Worcester Royal Hospital, Worcester, UNITED KINGDOM, ⁵University of Lincoln, Lincoln, UNITED KINGDOM.

66   Prostate Specific Antigen: Responsible Allergen In Human Seminal Plasma Allergy

M. Basagaña ¹, C. Pastor², B. Bartolomé³, R. Alonso¹, M. San Miguel¹, A. Cisteró-Bahíma¹; ¹Institut Universitari Dexeus, Barcelona, SPAIN, ²Fundación Jimenez-Díaz, Madrid, SPAIN, ³I+D Bial-Aristegui, Bilbao, SPAIN.

67   Development of Hypocomplementemic Urticarial Vasculitis Syndrome Following Intracoronary Stent Placement

S. L. Cole, D. K. Ledford; University of South Florida, Tampa, FL.

68   Treatment of Hypoglycemia with Intramuscular Immunoglobulin in Insulin Dependent-Diabetics with Insulin Antibodies

S. A. MacLeish, S. Wallace, Z. Madhun, R. Hostoffer, Jr.; Case Western Reserve University, Cleveland, OH.

69   A Case of a Child with Autoimmune Polyglandular Syndrome(APS-1) associated with Metaphyseal Dysplasia

T. J. Pitt, N. K. Maclaren; St Vincent Hospital Manhattan, Department of Pediatrics, New York, NY.

70   Behçet Disease in a Patient with Autoimmune Polyendocrine Syndrome -Type 1

Ö. Özdemir; Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

71   Autoimmune Neonatal Chondrodysplasia Punctata and Maternal Lupus

R. Herzog ¹, L. J. Bernstein¹, A. L. Shanske²; ¹Division of Allergy and Immunology, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY, ²Center for Craniofacial Disorders, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY.

72   Hyperinsulinemia Hyperammonemia Syndrome in a patient with autoimmune disease

R. V. Basavaraju; Kansas University Medical Center, Kansas City, KS.

73   Fever of Unknown Origin (FUO) and Anemia as Sole Presenting Features of Sarcoid

T. Chacko, D. Ledford, R. F. Lockey; University of South Florida Collge of Medicine, Tampa, FL.

74   Pancytopenia and Myelofibrosis in Autoimmune Polyglandular Syndrome Type I

M. Braskett, M. I. Garcia-Lloret, S. Howenstine, D. McCurdy, S. McGhee; UCLA, Los Angeles, CA.

75   Autoimmune Thyroiditis Developing In A Survivor Of Catastrophic Antiphospholipid Syndrome: A Case Report

C. C. Ocampo, L. T. A. Aleta, M. W. Sumpaico; Section of Allergy and Immunology, Department of Medicine, University of the Philippines - Philippine General Hospital, Manila, PHILIPPINES.

76   Ischemic Events in Pacients with Systemic Lupus Erythematosus

M. E. Flores^1,2, M. E. Contreras ¹, I. A. Bello¹, L. A. Aranguren¹, E. Marti¹; ¹Universidad de Carabobo, Valencia, VENEZUELA, ²Ciudad Hospitalaria Dr. Enrique Tejera, Valencia, VENEZUELA.

77   Antibodies Anti-cmv In Patient With Myocardial Ischemia

M. E. Flores Chávez ¹, M. Chacón de Petrola², C. Celis³, A. Chiquito³, N. Figueroa³, I. Petrola⁴; ¹Unidad de Inmunologia. Ciudad Hospitalaria Enrique Tejera, Valencia, VENEZUELA, ²Unidad de Investigaciones en Inmunologia Clinica. UC., Valencia, VENEZUELA, ³Universidad de Carabobo, Valencia, VENEZUELA, ⁴Unidad de Cuidados Coronarios. Ciudad Hospitalaria Enrique Tejera, Valencia, VENEZUELA.

78   A 54 Year-Old Woman with Acquired Angioedema, Coagulopathy, and Lymphoma

E. L. Pratt, S. Chegini, T. Craig; Penn State Milton S. Hershey Medical Center, Hershey, PA.

79   Abdominal pain, Nausea, and Vomiting as the Initial Presenting Symptoms of Systemic Lupus Erythematosus

B. Shin, D. K. Ledford, R. F. Lockey; Division of Allergy and Clinical Immunology, University of South Florida College of Medicine, Tampa, FL.

80   Mucosal administration of Escherichia coli Heat-labile toxin B and Classical swine fever E2 Chimeric antigen inhibits collagen-induced rheumatoid arthritis

D. Kim; Chonnam national university, Gwang-ju, REPUBLIC OF KOREA.

Poster Session

2205

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Environmental Determinants and Asthma

81   IgE-Mediated Hypersensitivity Reactions to Cannabis in Laboratory Personnel

T. Herzinger, F. Ruëff, P. Schöpf, B. Przybilla; Ludwig-Maximilians-Universität, Munich, GERMANY.

82   Multiple Chemical Sensitivity: an Unusual Case of Vocal Disorder

M. Medeiros, Jr., H. B. Santos, C. Salles, H. Rosa; Allergic Center Diseases, Salvador - Bahia, BRAZIL.

83   Effect of Training on Asthma and Allergy Symptoms in Recreational Roadrunners

C. C. R. Randolph ¹, D. Dreyfus¹, D. Bangalore², L. Wall¹; ¹Center for Allergy, Asthma and Immunology, Waterbury, CT, ²Waterbury Hospital, Waterbury, CT.

84   Occupational Mouse Allergen Exposure and Incident Skin Test Sensitivity

E. C. Matsui ¹, B. J. Paigen², E. A. O'Neil², K. A. Hagberg², P. A. Eggleston¹; ¹Johns Hopkins University School Medicine, Baltimore, MD, ²The Jackson Laboratory, Bar Harbor, ME.

85   Hypersensitivity Pneumonitis Caused by Trichoderma Viride

A. Enríquez-Matas ¹, S. Quirce¹, R. Melchor¹, M. J. Rodríguez-Nieto¹, J. Carnés², M. Madero¹, J. A. Torres¹, J. Sastre¹; ¹Fundación Jiménez Díaz, Madrid, SPAIN, ²Leti, Madrid, SPAIN.

86   An Age-stratified Assessment Of The Incidence Allergic Diseases Among Patients From Western Hungary

L. Sóti ¹, Z. Petz¹, L. Endre², L. Réthi³, L. M. DuBuske⁴; ¹Szombathely Allergy-Asthma Outpatient Clinic, Szombathely, HUNGARY, ²Budapest National Health Institute, Budapest, HUNGARY, ³Svábhegy National Institute of Pediatrics, Budapest, HUNGARY, ⁴Immunology Research Institute of New England, Gardner, MA.

87   Occupational Asthma Secondary To Enzymes Used In Cheese Production

R. M. Casper, M. C. Zacharisen, J. N. Fink; Medical College of Wisconsin, Milwaukee, WI.

88   IgE and Skin Test Reactivity in relation to Anti-parasitic treatment

E. E. Fouda ¹, A. I. Ali¹, M. Emam², A. S. Abdel Khalek¹; ¹Al-Azhar Allergy & Immunology University Center, Cairo, EGYPT, ²Al-Azhar University faculty of medicine, Cairo, EGYPT.

89   Occupational Contact Urticaria Syndrome Caused By Handling Lettuce And Chicory: Cross-reactivity Between Lettuce And Chicory

A. Morita ¹, N. Inomata¹, M. Kondou², T. Shirai³, Z. Ikezawa¹; ¹Department of Dermatology,Yokohama City University, Yokohama, JAPAN, ²Kondou Dermatology Clinic, Yokohama, JAPAN, ³Department of Internal Medicine, Fujinomiya City Hospital, Japan, Fujinomiya, JAPAN.

90   Asthma Prevalence and Morbidity Among Rural Schoolchildren in the Mississippi Delta

T. T. Perry, S. M. Jones, J. R. Stalnaker, K. R. Nichols, P. A. Vargas; University of Arkansas for Medical Sciences, Little Rock, AR.

91   Asthma and Mycoplasma pneumoniae infection

Y. Park; Wonkwang University Sanbon Medical Center, Gunpo City, REPUBLIC OF KOREA.

92   Is Obesity Related To Severity And Frequency Of Asthma Symptoms?

F. Hassan ^1,2, P. Patel², E. Secord²; ¹Woodhull medical center, Brooklyn, NY, ²The Carmen and AnAdams Dept. of Pediatrics, Children hospital of Michigan, Wayne State University, Detroit, MI.

93   Characteristics of Asthma Programs with Positive Health Outcomes

A. R. Friedman, L. L. Lachance, S. C. Stoll, D. F. Awad, N. M. Clark; University of Michigan School of Public Health, Ann Arbor, MI.

94   Detection of Underdiagnosed and Poorly Controlled Asthma in a Hospital-Based Outpatient Pediatric Clinic using a Health Risk Assessment (HRA) System

B. Nichols ¹, L. Scott¹, S. Jones², K. Kwong¹, T. Morphew³, L. T. Clement¹, F. Lifson³, C. A. Jones^1,3; ¹LAC+USC Medical Center, Los Angeles, CA, ²LAC+USC Medical Center Volunteer Program, Los Angeles, CA, ³Southern California Chapter of the Asthma and Allergy Foundation of America, Los Angeles, CA.

95   The Asthma Day Care Project: Identifying and Managing Asthma in Brooklyn Preschools

A. R. Padi, K. Garrett-Szymanski, C. Willis, B. Silverman, R. Giusti, A. Schneider; Long Island College Hospital, Brooklyn, NY.

96   Dust And Airborne Concentrations Of Endotoxins In Strasbourg And In A Rural Environment (Haut-Doubs)

F. de Blay ¹, G. Reboux², A. Casset¹, S. Roussel², K. Humbert², B. Sudre², R. Piarroux², J. Dalphin²; ¹Asthma and Allergy Division, Department of Chest Diseases, University Hospital, Strasbourg, FRANCE, ²University Hospital, Besançon, FRANCE.

97   Allergy To Cumaru (Dipterix micrantha Harms) Tropical Wood

F. de la Losa, Sr.; DIATER Laboratories, San Martin de la Vega, SPAIN.

98   Impact of Absences due to Asthma on Total School Absences in Upstate New York Elementary Schools

E. Simons, A. Reddy, M. Gomez, C. Kielb, S. Lin; New York State Department of Health, Center for Environmental Health, Albany, NY.

99   Effects of Cigarette Smoke Extract and Rhinovirus on Expression of B7H1 and B7H3 in Human Airway Epithelial Cells

E. Schafer, S. Favoreto, J. Shen, R. Dave, P. C. Avila; Northwestern University, Chicago, IL.

100   The Long-term Effects Of Diesel Exhaust Particles On Airway Inflammation And Responsiveness In A Mouse Model

A. Jang; Soonchunhyang University Hospital, Bucheon, REPUBLIC OF KOREA.

101   Quantity of Rhinovirus in Nasal Lavage Does Not Predict Illness Severity

J. D. Bufford ¹, K. A. Roberg¹, T. E. Pappas¹, R. F. Vrtis¹, M. D. Evans², R. E. Gangnon², R. F. Lemanske, Jr.¹, J. Gern¹; ¹University of Wisconsin School of Medicine and Public Health, Madison, WI, ²University of Wisconsin-Madison, Madison, WI.

Poster Session

2206

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Anaphylaxis, Venom and Latex

102   Elucidating The Cause Of Peri-operative Allergic Reactions-Correlation Between Clinical Features, Skin Testing Data And Serum Tryptase Levels

C. H. Katelaris; Westmead Hospital, Westmead, AUSTRALIA.

103   Dose-Dependant Angioedema Due to Sirolimus

A. Kleiner, R. Srinivasan, R. J. Looney; Allergy/Immunology and Rheumatology Unit, University of Rochester Medical Center, Rochester, NY.

104   Differences in the Allergic Response Induced by Live or Dead Anisakis Simplex Larvae in C3H/HeJ Mice

M. L. Baeza, Y. Higaki, L. Conejero, A. Torrecilla, M. Vazquez de la Torre, M. Rubio, J. M. Zubeldia; Hospital General Universitario Gregorio Marañón, Allergy Service and Experimental Medicine Unit, Madrid, SPAIN.

105   Drug Anaphylaxis As Presentation of Systemic Mastocytosis: About 7 Case Reports

F. Codreanu, M. Morisset, J. M. Renaudin, A. Schuller, J. Mouzita, E. Beaudouin, D. A. Moneret-Vautrin, G. Kanny; University Hospital, Nancy, FRANCE.

106   The Availability of EpiPens® Used by Students with Severe Food allergies in Michigan Schools

D. Kassab ¹, E. A. Robinson², A. Russell¹, M. McMorris¹; ¹University of Michigan, Ann Arbor, MI, ²St. Joseph Mercy Hospital, Ann Arbor, MI.

107   Prevalence of Allergy and Anaphylaxis in 210 Patients with Mastocytosis

A Study From The Spanish Network on Mastocytosis (REMA)

D. González de Olano ¹, M. B. de la Hoz Caballer¹, R. Nuñez López¹, L. Sánchez Muñoz¹, M. Cuevas Agustín¹, M. Dieguez¹, M. Castells², L. Escribano Mora¹; ¹Hospital Ramón y Cajal, Madrid, SPAIN, ²Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

108   Anaphylaxis As An Initial Manifestation Of Cholangiocarcinoma

P. Ngamjanyaporn ¹, S. Janwityanujit¹, P. Dekumyoy²; ¹Department of Internal Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND, ²Department of Helminthology, Faculty of Tropical Medicine, Mahidol University, Bangkok, THAILAND.

109   Superior Vena Cava Syndrome: A Masquerader of Anaphylaxis

B. Khalili ¹, P. B. Boggs², S. L. Bahna¹, A. J. Marsala³, M. Tapolyai³, R. O. Bryn³; ¹LSUHSC Allergy & Immunology Section, Shreveport, LA, ²Asthma and Allergy Clinic and Center of Excellence, Shreveport, LA, ³Willis-Knighton Medical Center, Shreveport, LA.

110   Use Of Epinephrine In Food-induced Anaphylaxis In Children

K. M. Jarvinen, W. G. Shreffler, H. A. Sampson, S. Noone, A. Nowak-Wegrzyn; Mt. Sinai Hospital, New York, NY.

111   Food-Dependent Exercise-Induced Anaphylaxis Associated with Clonal Mast Cells Carrying an Activating c-Kit Mutation

S. I. Hungness, A. M. Singer, C. Akin; University of Michigan, Ann Arbor, MI.

112   Maturation of the IgE and IgG response to Imported Fire Ant Venom during natural exposure

M. Partridge ¹, D. Ownby¹, R. Hamilton², P. Young¹, J. Ford¹; ¹Medical College of Georgia, Augusta, GA, ²Johns Hopkins Hospital, Baltimore, MD.

113   Recent Trends in Hymenoptera Sensitivity Evaluation

L. C. Cary ¹, J. Temprano²; ¹Department of Internal Medicine, Divison of Allergy, Asthma and Immunology, Univeristy of Kentucky, Lexington, KY, ²Department of Internal Medicine, Division of Allergy, Asthma, and Immunology, Univeristy of Kentucky, Lexington, KY.

114   The Uses of MALDI-TOF Mass Spectrometry in Characterization of Allergens

D. R. Hoffman; Brody School of Medicine at East Carolina University, Greenville, NC.

115   IgE Reactivity to Recombinant Omega-5 Gliadin in Wheat-Dependent Exercise-Induced Anaphylaxis

H. Matsuo ¹, J. Dahlström², K. Kohno³, H. Takahashi³, E. Morita³; ¹Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JAPAN, ²Research and Development, Phadia, Uppsala, SWEDEN, ³Department of Dermatology, Shimane University School of Medicine, Shimane, JAPAN.

116   Production and Analysis of the Allergenic Venom Serine Protease from Polistes dominulus

C. D. Fitch¹, M. Schmidt², D. R. Hoffman ³; ¹Brody School of Medicine, Greenville, NC, ²E. Carolina University, Greenville, NC, ³Brody School of Medicine, Greenville, NC.

117   New Diagnostic Approaches for Wasps Venom Allergy

R. I. Monsalve ¹, R. Gutierrez¹, F. Polo¹, M. Lombardero¹, A. Galan¹, T. P. King², L. Marques³, D. Barber¹; ¹ALK-ABELLO, Madrid, SPAIN, ²Rockefeller University, New York, NY, ³SEAIC Hymenoptera Committee, Lleida, SPAIN.

118   Identification of an Allergenic Lipid Transfer Protein in Pomegranate-Induced Anaphylaxis

M. San Miguel-Moncín ¹, M. Lombardero², D. Barber², E. Enrique³, R. Alonso¹, M. Basagaña¹, A. Cisteró-Bahima¹; ¹Allergy Department. Institut Universitari Dexeus, Barcelona, SPAIN, ²R & D Dept. ALK-Abello S. A., Madrid, SPAIN, ³Servicio de Alergia. Hospital General de Castellón, Castellón, SPAIN.

119   Anaphylaxis Due To Buckwheat Skin Testing

Y. K. Cheng; Tan Tock Seng Hospital, Singapore, SINGAPORE.

120   Sensitization to Egg Via Inhalation of Egg Aerosol Resulting in Anaphylaxis

J. E. Yoo; University CA-San Francisco, San Francisco, CA.

121   Comparison of a Modified Yellow Jacket Venom Extract (Allergoid) with Conventional Yellow Jacket Venom (Aluminium hydroxide bounded) for the Treatment of Yellow Jacket Allergy by Sting Challenges

H. N. G. Oude Elberink ¹, H. A. Kleinjans², H. de Groot³; ¹University Medical Center of Groningen, Groningen, THE NETHERLANDS, ²HAL Allergy, Haarlem, THE NETHERLANDS, ³Erasmus Medical Center, Rotterdam, THE NETHERLANDS.

122   Hospitalizations for Anaphylaxis in Florida: Epidemiologic Analysis of a Population-Based Dataset

Z. D. Mulla ¹, M. R. Simon²; ¹Texas Tech University HSC School of Medicine at El Paso, El Paso, TX, ²Wayne State University School of Medicine, Detroit, MI.

123   Prevalence of Latex Sensitization and Allergy among handicapped patients

I. Kobayashi ^1,2, K. Kitsuki^3,2, S. Yamamoto², T. M. Horiuti¹, R. M. Goldblum¹, Y. Hamasaki²; ¹University of Texas Medical Branch, Galveston, TX, ²Medical University of Saga, Saga city, JAPAN, ³Saga seishi-gakuen Child Development Medical Center, Saga city, JAPAN.

124   Fast-Disintegrating Sublingual Epinephrine Tablets: High Temperature Stability Study

M. M. Rawas-Qalaji, F. E. R. Simons, K. J. Simons; University of Manitoba, Winnipeg, MB, CANADA.

125   Latex Allergy: Low Prevalence of IgE to Highly Purified Hev b 2 and Hev b 13

T. Palosuo ¹, M. Lehto², A. Kotovuori³, N. Kalkkinen³, C. Blanco⁴, P. Poza⁴, T. Carrillo⁴, R. G. Hamilton⁵, H. Alenius², T. Reunala⁶, K. Turjanmaa⁶; ¹National Public Health Institute, Helsinki, FINLAND, ²Finnish Institute of Occupational Health, Helsinki, FINLAND, ³Institute of Biotechnology, University of Helsinki, Helsinki, FINLAND, ⁴Servicio de Alergia, Hospital Universitario de Gran Canaria, Las Palmas de Gran Canaria, SPAIN, ⁵Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, ⁶Department of Dermatology, Tampere University and University Hospital, Tampere, FINLAND.

126   Imported Fire Ant Sublingual Immunotherapy for Large Local Reactions

M. H. Tucker, C. W. Calabria, L. L. Hagan, J. P. Dice; Wilford Hall Medical Center, San Antonio, TX.

127   Single Intragastric Peanut Feeding Leads To Anaphylactic Shock In C3H/HeJ But Not In BALB/c Or C57BL/6 Mice

B. Proust ¹, C. M. N. Astier², S. Jacquenet³, V. Ogier³, E. Magueur³, B. Thouvenot³, M. Morisset¹, D. A. Moneret-Vautrin¹, H. A. Sampson⁴, A. W. Burks⁵, B. E. Bihain³, G. Kanny¹; ¹University Hospital, Vandoeuvre-Les-Nancy, FRANCE, ²INPL, Vandoeuvre-Les-Nancy, FRANCE, ³Laboratory of Molecular Medicine and Therapeutics, Vandoeuvre-Les-Nancy, FRANCE, ⁴Mount Sinaï Hospital, New-York, NY, ⁵Duke University Medical Center, Durham, NC.

128   Methylene Blue as a Treatment for Refractory Anaphylaxis

S. S. Sheth, D. Del Duca, P. Ergina, A. E. Clarke; McGill University Health Centre, Montreal, PQ, CANADA.

129   Anaphylaxis: Report of Two Fatal Yellow Jacket (YJ) Stings in Alaska (AK)

M. L. Oswalt ¹, J. T. Foote², S. F. Kemp¹; ¹University of Mississippi Medical Center, Jackson, MS, ²Tanana Valley Clinic, Fairbanks, AK.

130   Anaphylaxis Caused by Younger Garlic: Two Cases Report in China

J. Yin, H. Li; Allergy Department, Peking Union Medical College Hospital, Beijing, CHINA.

131   Recurrent Panic/Anxiety Attacks: Masquerader of Anaphylaxis and Challenge to Comprehensive History Taking

C. D. Friesen ¹, R. J. M. Engler²; ¹Carl R. Darnall Army Medical Center, Fort Hood, TX, ²Walter Reed Army Medical Center-VHC, Washington, DC.

132   Anaphylaxis in a Patient with Long QT Syndrome

P. Permaul, L. C. Schneider, J. Triedman; Children's Hospital Boston, Boston, MA.

133   A Case Report on Immunotherapy in Recurrent Anaphylaxis using the Whole-Body Extract of Fire Ant

P. Rojponpradit ¹, S. Benjaponpitak¹, W. Kamchaisatian¹, C. Direkwattanachai¹, C. Sasisakulporn²; ¹Division of Pediatric Allergy and Immunology, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND, ²Center of Research, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND.

134   Anaphylaxis to Honey in a Patient Sensitized to Compositae Pollen

N. Fuiano ¹, G. Riario-Sforza², C. Incorvaia²; ¹Pediatric Allergy Service, A.USL Fg1, San Severo, ITALY, ²Allergy and Pulmonary rehabilitation, ICP Hospital, Milano, ITALY.

135   Successful Desensitization in a Severe Hemophilia B patient with IgE-mediated Anaphylaxis to Factor IX

Y. Moonsup ¹, S. Benjaponpitak¹, A. Chuansumrit², W. Kamchaisatian¹, C. Direkwattanachai¹; ¹Division of Allergy and Clinical Immunology, Department of Pediatrics, Ramathibodi hospital, Mahidol University, Bangkok, THAILAND, ²Division of Hematology, Department of Pediatrics, Ramathibodi hospital, Mahidol University, Bangkok, THAILAND.

Poster Session

2207

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Drug Allergy I

136   Humoral Immune Responses to Cosmetically-Administered Hyaluronic Acid (Perlane and Restylane)

R. G. Hamilton ¹, J. Strobos², N. F. Adkinson, Jr.¹; ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Medicis Pharmaceutical Corporation, Scottsdale, AZ.

137   Safety of a Single Day Aspirin Desensitization Protocol

B. L. Buchmiller, D. A. Khan; University of Texas Southwestern Medical School at Dallas, Dallas, TX.

138   Rapid Oral Aspirin Challenge-Desensitization in Patients With Symptomatic Acute Coronary Syndrome

M. Michelis, K. Bianco, T. Selvaggi, A. Oughourli; Hackensack University Medical Center, Hackensack, NJ.

139   Severe Drug-Induced Anaphylaxis: Survey of Case Reports by Allergy Vigilance Network

J. M. C. Renaudin, G. Kanny, F. Codreanu, E. Beaudouin, D. A. Moneret-Vautrin; University Hospital, Nancy, FRANCE.

140   Specific Subpopulation Involved in Allergic Delayed Responses to Amoxicillin in an in Vitro System with Autologous Dendritic Cells

R. R-Pena ¹, S. Lopez¹, C. Antunez¹, P. Chaves¹, C. Mayorga¹, M. J. Torres², T. D. Fernandez¹, J. A. Cornejo-Garcia¹, M. Blanca²; ¹Research Laboratory, Fundacion IMABIS-Carlos Haya Hospital, Málaga, SPAIN, ²Allergy Service, Carlos Haya Hospital, Málaga, SPAIN.

141   Coexistence of Atopic Diseases and Idiosyncratic Reactions to Aspirin

A. A. Nowak ^1,2, M. Nowak², A. Muszyñska^3,2, A. M. Fal⁴; ¹1st Department of Paediatrics, Allergology and Cardiology, Medical University, Wroclaw, POLAND, ²Allergology and Clinical Immunology Students Scientific Research Group, Medical University, Wroclaw, POLAND, ³Department of Family Medicine, Medical University, Wroclaw, POLAND, ⁴Department of Internal Medicine and Allergology, Medical University, Wroclaw, POLAND.

142   Exudative Erythema Multiforme With Hydroxyzine

A. Losada, E. Gonzalez, A. Henriquez, B. Huertas, P. Berges, E. Alvarez; Servicio de Alergia. Hospital Ramon y Cajal, Madrid, SPAIN.

143   Reliability of Drug Allergy History in Foreign Tourists

M. OKADA; St. Luke's International Hosiptal, 104-8560 Tokyo, JAPAN.

144   Putative B-cell Apoptosis as a Cause of Hypogammaglobulinemia in Carbamazepine Hypersensitivity: A Case Report

J. A. Bird, D. M. Anmuth, E. Muscal, M. K. Dishop, C. L. Nance, S. L. Abramson; Baylor College of Medicine, Houston, TX.

145   Cross-reactivity Between Penicillins and Cephalosporins with the Same Side Chain: Amoxicillin and Cefadroxil

M. J. Torres ¹, N. Blanca-Lopez², E. Martin¹, C. Mayorga³, J. L. Rodriguez-Bada³, I. Doña¹, G. Canto², C. Antunez³, J. J. Romero¹, M. Blanca¹; ¹Allergy Service, Carlos Haya Hospital, Málaga, SPAIN, ²Allergy Service, Doce de Octubre Hospital, Madrid, SPAIN, ³Research Laboratory, Fundacion IMABIS-Carlos Haya Hospital, Málaga, SPAIN.

146   Stevens-Johnson Syndrome From Oral Acetazolamide In A 19-Year Old Male

G. B. Velez ¹, K. S. Estrellado², R. G. Tabigo-on², C. J. Gloria¹, M. W. Sumpaico¹; ¹University of the Philippines-Philippine General Hospital Section of Allergy and Immunology, Manila, PHILIPPINES, ²University of the Philippines-Philippine General Hospital Department of Medicine, Manila, PHILIPPINES.

147   Metronidazole-Induced Encephalopathy in a Pediatric Patient

A. Gaye, A. Sanghavi; Loyola University Medical Center, Maywood, IL.

148   Sequential Drug Provocation Testing in Diagnosis of an Unusual Fixed Drug Eruption to Pseudoephedrine

Y. K. Cheng; Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, SINGAPORE.

149   Eosinophilia During Piperacillin-Tazobactam (Pip/Taz) IV Desensitization

J. G. Kemp, N. L. Rider, G. Ghaffari, E. L. Pratt, J. G. Gibbs, S. Chegini, T. J. Craig; Penn State College of Medicine Milton S. Hershey Medical Center, Hershey, PA.

150   New Orleans Seniors on Polypharmacy: The Impact of Intervention on Adverse Drug Reactions (ADR) and Cost of Medications

P. Kumar, K. Elshatory, C. Vital, S. Kamboj; LSU medical center, New Orleans, LA.

151   Optimising the Lymphocyte Transformation Test in Drug Allergy Diagnosis

E. M. M. Tomaz, M. R. Viseu, A. F. Ferrão, S. H. Correia, M. J. Peres, R. P. Reis, L. A. Patricio, F. C. Inacio; Hospital S. Bernardo, Setúbal, PORTUGAL.

152   Persistent Eosinophilia Following Aspirin Desensitization in a Patient with Aspirin Exacerbated Respiratory Disease

N. M. Vogel, D. M. Lang, F. H. Hsieh; The Cleveland Clinic Foundation, Cleveland, OH.

153   Type I Allergy to Benzoimidazole Antihelmintics

R. González-Mendiola ¹, T. Palomeque Rodríguez¹, N. Martínez Borque¹, M. Torrecillas Toro¹, D. Martínez Bohigas¹, J. Solera²; ¹Complejo Hospitalario Universitario de Albacete. Allergy Department, Albacete, SPAIN, ²Complejo Hospitalario Universitario de Albacete. Internal Medicine Department, Albacete, SPAIN.

154   Immediate Hypersensitivity Reactions to Methylprednisolone in Children

A. Nahum ^1,2, B. Garty¹, Y. Levy¹; ¹Kipper Institute of Immunology, Schneider Children's Medical Center of Israel, Petah Tiqva, ISRAEL, ²Department of Pediatrics, Kaplan Medical Center, Rehovot, ISRAEL.

155   Prevalence of Drug Adverse Reactions in Out-Patients

M. Palma-Carlos, M. Medina, A. G. Palma-Carlos; Clinical Allergy Immunology Center, Lisbon, PORTUGAL.

156   Skin Reaction after Desensitization Not Predict the Outcome of Short Course Sulfa Desensitization Protocol among AIDS Patients

W. Maek-A-Nantawat ¹, H. Chantaphakul², K. Ruxrungtham²; ¹Mahidol University, Bangkok, THAILAND, ²Chulalongkorn University, Bangkok, THAILAND.

157   Monitoring the Peripheral Blood Lymphocyte Subtypes in Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)

M. Yazicioglu ¹, R. Elmas¹, T. Genchallacoglu¹, S. Yildirim¹, B. Turgut²; ¹Trakya University, Department of Pediatrics, Edirne, TURKEY, ²Trakya University, Department of Internal Medicine, Edirne, TURKEY.

158   Allergy To Multiple Local Anesthetics

A. B. Caron; Clinique Concorde, Laval, PQ, CANADA.

Poster Session

2208

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Quality of Life

159   Development of Health-Related Quality of Life Questionnaires for Children, Adolescents and Adults with Food Allergy: the Item Reduction

B. M. J. de Blok ¹, A. DunnGalvin², J. N. G. Oude Elberink³, B. J. Vlieg-Boerstra¹, E. J. Duiverman¹, J. B. Hourihane², A. E. J. Dubois^1,3; ¹University Medical Center Groningen, University of Groningen, Beatrix Children's Hospital, Department of Paediatric Pulmonology and Allergology, Groningen, THE NETHERLANDS, ²Cork University Hospital, Department of Paediatrics and Child Health, Cork, IRELAND, ³University Medical Center Groningen, University of Groningen, Department of Allergology, Groningen, THE NETHERLANDS.

160   Impact of Pediatric Asthma and Treatment on Care-givers Visiting Specialist Clinics in Japan

Y. Ohya ¹, H. Watanabe¹, N. Kojima¹, T. Katsunuma², N. Kondo³, A. Akasawa¹; ¹National Center for Child Health and Development, Tokyo, JAPAN, ²The Jikei University, Tokyo, JAPAN, ³Gifu University, Gifu, JAPAN.

161   Once-A-Day Olopatadine Improves the Health-Related Quality-Of-Life of Allergic Conjunctivitis Patients

G. J. Berdy ¹, S. V. Scoper², S. J. Lichtenstein³, J. M. Rubin⁴, C. Waycaster⁵, T. Pasquine⁵, R. D. Gross⁵, S. Robertson⁵; ¹Ophthalmology Associates, St. Louis, MO, ²Virginia Eye Consultants, Norfolk, VA, ³Louisville Children's Eye Specialists, Louisville, KY, ⁴Eye Clinics of South Texas, San Antonio, TX, ⁵Alcon Research Ltd., Fort Worth, TX.

162   Health Related Quality of Life in Lithuanian Children with Asthma

E. Vaitkaitiene; Biomedical Research Institute of Kaunas University of Medicine, Kaunas, LITHUANIA.

163   Developmental Trajectories in Food Allergy: Sex and Age Differences

J. O. B. Hourihane, A. DunnGalvin; University College Cork, Cork, IRELAND.

164   Does Childhood Asthma Affect The Quality Of Life Of Caregivers?

Z. Tamay ¹, A. Akcay², N. Guler¹, A. Suleymanoglu¹, G. Kilic¹, U. Ones¹; ¹Istanbul Medical Faculty, Istanbul, TURKEY, ²Pamukkale Medical Faculty, Denizli, TURKEY.

165   Adverse Effects of Danazol in the Prophylactic Treatment of Hereditary or Acquired C1-Inhibitor Deficiency

W. Kreuz, E. Aygören-Pürsün, I. Martinez-Saguer, E. Rusicke, T. Klingebiel; University Hospital Frankfurt, Frankfurt, GERMANY.

Poster Session

2209

Saturday, February 24, 2007

9:45 AM - 10:45 AM

T cells

166   T-Cell Receptor (TCR)-Mediated Upregulation of BLT1 (LTB4 Receptor) Expression and Activation of Human T Cells by LTB4

A. Ahuja, A. Dakhama, H. Ohnishi, J. J. Lucas, E. W. Gelfand; National Jewish Medical and Research Center, Denver, CO.

167   The Role Of Th1 And Th2 Response In Allergic Rhinitis Children With Or Without Sensitization To Food Allergens

A. Nakonechna ¹, T. Umanetz², V. Lapshin², A. R. D. van Bergen³; ¹National Medical University, Kiev, UKRAINE, ²Institute of Pediatry, Obstetrics and Gynaecology, Kiev, UKRAINE, ³Novidec Ltd, Neston, UNITED KINGDOM.

168   CD4+CD25+ Cells and Laboratory Animal Allergy

H. Jeal, A. Newman Taylor, M. Jones; NHLI @ Imperial College, London, UNITED KINGDOM.

169   IL-5 production In Response To Candida Albicans Secretory Aspartic Protease 2 Is Associated With Isolated Late-phase Bronchial Response Upon Inhalation Challenge

A. Mori, N. Kitamura, T. Hashimoto, M. Taniguchi, M. Otomo, Y. Maeda, M. Hasegawa, K. Akiyama; National Sagamihara Hospital, Clinical Research Center, Sagamihara, JAPAN.

170   Critical Role For Adaptive T Cell Immunity In Experimental Eosinophilic Esophagitis In Mice

A. Mishra, J. Schlotman, M. Wang, M. E. Rothenberg; Childrens Hospital Medical Center, Cincinnati, OH 45229, Cincinnati, OH.

171   Allergen-specific CD4 T & B Cells in Allergic Patients are NOT Increased Compared to Nonallergic Individuals

A. Ueno, C. Lu, B. Serushago, T. Bowen, J. Storek; University of Calgary, Calgary, AB, CANADA.

172   Profound Lymphopenia in Two Immunocompetant Children With Allergic Fungal Sinusitis

D. R. Naimi, J. M. Spergel; The Children's Hospital of Philadelphia, Philadelphia, PA.

173   Association Between Second Hand Smoke Exposure (SSE) and T-Helper Type 2 (TH2) Cytokine Production During Early Childhood

A. Patel, D. A. Gentile, J. M. Koehrsen, D. P. Skoner, M. Varga, C. A. Schad, T. J. Schaffner; Allegheny General Hospital, Pittsburgh, PA.

174   Activation Of Allergen-specific T Cells In Vivo During Specific Immunotherapy With Depigoid Allergen Extracts

E. O. Luger, H. Lee, D. Ernst, M. Worm; Dept. of Dermatology and Allergy, Berlin, GERMANY.

175   EBI3 Deficient Naive T cells Show Increase in Expression of Th2 Mediated Cytokines In-vitro

E. Dokmeci ¹, L. Xu¹, R. Blumberg², K. Bottomly¹; ¹Yale University, New Haven, CT, ²Brigham & Womens Hospital, Boston, MA.

176   The Tyrosine Kinase Txk/Rlk Rescues The Development Of Allergic Asthma In Mice Lacking Tec Kinase Itk

N. SAHU; PENNSTATE UNIVERSITY, State college, PA.

177   Mast Cell Mediated LTB4-BLT1 Pathway in Asthma and the Therapeutic Role of Zileuton in Regulating Early T Cell Trafficking in Airways

Z. Mikhak, M. Fukui, P. Hesterberg, A. D. Luster; Massacusetts General Hospital, Charlestown, MA.

178   Living in Farming Communities (FC) Provides Children Greater Protection Against Asthma Attacks than Living in Poor Hygienic Conditions (PHC)

S. Sur ¹, S. Chitranshi², S. Ganesh³, R. Moona³, M. Sharma³, S. Bajpai³, S. K. Katiyar⁴; ¹University TX Medical Branch, Galveston, TX, ²RAMA Hospital, Kanpur, INDIA, ³Indian Institute of Technology, Kanpur, INDIA, ⁴GSVM Medical College, Kanpur, INDIA.

179   Pharmacological Effects of ASM8, an Antisense Oligonucleotide to CCR3 and the Common Beta Chain Receptor in Mild Asthmatics

G. M. Gauvreau ¹, L. P. Boulet², D. W. Cockcroft³, M. Duong¹, H. D'Anjou⁴, P. M. Renzi^4,5, P. M. O'Byrne¹; ¹McMaster University, Hamilton, ON, CANADA, ²Hopital Laval, Université Laval, Quebec City, PQ, CANADA, ³University of Saskatchewan, Saskatoon, SK, CANADA, ⁴Topigen Pharmaceuticals Inc, Montreal, PQ, CANADA, ⁵University of Montreal, Montreal, PQ, CANADA.

180   Adoptive Transfer of Splenocytes from Immunotherapy Group Ameliorating the Histopathological Changes and Increased IL-10 and IFN-g Levels in the Recipient Mice

T. Akkoc; Marmara University, Istanbul, TURKEY.

181   Airway Exposures to House Dust Extracts Provide Th2 Adjuvant Activity with Intermittent Delivery and Long Term Tolerogenic Activity with Daily Delivery

G. M. Batzer, N. Ng, D. P. Lam, A. A. Horner; UCSD, La Jolla, CA.

182   Neonatal Education of Dendritic and T Cells by LPS results in Tolerance in an Adoptive Transfer Model of Airways Allergy

Y. Wang, C. T. McCusker; McGill University, Montreal, PQ, CANADA.

183   Peripherally-Induced Allergen-Specific Foxp3+ Regulatory T Cells are Essential for the Control of Chronic Allergic Lung Inflammation

M. A. Curotto de Lafaille, N. Kutchukhidze, Y. Ding, S. Shen, J. J. Lafaille; New York University School of Medicine, New York, NY.

184   Sublingual Immunotherapy Induce Systemic T-cell Tolerance in Naive Mice

J. Brimnes, J. Kildsgaard, H. Jacobi, K. Lund; ALK-Abello, Hoersholm, DENMARK.

185   Mast Cells Promote the Development of CD103+ Regulatory T cells

Z. Allakhverdi, G. Delespesse; CHUM Research Center, Montreal, PQ, CANADA.

186   An Environmental Fungus, Alternaria, Stimulates OX40L and CCR7 Expression by Dendritic Cells (DCs)

T. Kobayashi ¹, S. Radhakrishnan², L. R. Pease², H. Kita¹; ¹Division of Allergic Diseases, Mayo Clinic College of Medicine, Rochester, MN, ²Department of Immunology, Mayo Clinic College of Medicine, Rochester, MN.

187   The Major Allergen From Peanut, Ara h 1, Induces Transcription Of Genes In Dcs That Are Important For Th2 Priming

Z. Y. Kucuk; Mount Sinai School of Medicine, New York, NY.

188   Eosinophils Modulate the Allergen-Indcued Th2 Pulmonary Immune Microenvironment

E. A. Jacobsen, S. Ochkur, A. G. Taranova, R. Pero, C. Protheroe, J. J. Lee; Mayo Clinic Arizona, Scottsdale, AZ.

189   Concomitant Use Of Glucocorticoids During Allergen Immunotherapy Upregulates Il-10 Production By Peripheral Blood Mononuclear Cells (pbmc)

P. Majak ¹, J. Jerzyńska¹, W. Stelmach¹, P. Kuna², I. Stelmach¹; ¹N.Copernicus Hospital, Lodz, POLAND, ²Medical University, Lodz, POLAND.

190   The Effect Of Allergen-pulsed Bone Marrow-derived Dendritic Cells In Mouse Asthma Mod Dose Not Depends On The Route Of Administration

M. Kim ¹, Z. Hahn², Y. Hahn¹; ¹Chungbuk National University, Cheongjoo, REPUBLIC OF KOREA, ²Chungbuk National University, Postgraduate School, Cheongjoo, REPUBLIC OF KOREA.

Poster Session

2210

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Mast Cells I

191   Conservation of Connective Tissue Mast Cells (MCs) for >500 Million Years of Evolution

R. L. Stevens ¹, L. Zhuo², B. Lam¹, K. Kimata², G. W. Wong³; ¹Brigham and Women's Hospital, Boston, MA, ²Aichi Medical University, Aichi, JAPAN, ³Whitehead Institute of Biomedical Research, Cambridge, MA.

192   Environmental Estrogens Induce Mast Cell Degranulation and Enhance IgE-mediated Release of Allergic Mediators

S. Narita, R. M. Goldblum, E. G. Brooks, C. S. Watson, M. D. Estes, E. M. Curran, T. Midoro-Horiuti; University of Texas Medical Branch, Galveston, TX.

193   Induction of Suppressor of Cytokine Signaling (SOCS)-1/3 by IFN-alpha in Suppressing IL-3- but not IgE- Dependent Signaling in Human Basophils

J. T. Schroeder, A. P. Bieneman, K. L. Chichester; Johns Hopkins University, Baltimore, MD.

194   Short Term Culture of Functional Human Mast Cells from Buffy Coat Preparations

M. Holm ^1,2, H. B. Andersen¹, C. Dahl¹, H. J. Hoffmann³, S. Junker², P. O. Schiotz¹; ¹Aarhus University Hospital, Aarhus, DENMARK, ²Institute of Human Genetics-University of Aarhus, Aarhus, DENMARK, ³Aarhus University Hospital-Resp. Dept, Aarhus, DENMARK.

195   Ras Guanine Nucleotide Releasing Protein 4 (RasgrP4) Dependent Pathways and Genes that Reversibly Control the Development, Phenotype, and Function of Human Mast Cells (MCs)]

G. P. Katsoulotos¹, K. Tanaka², T. J. Molloy³, R. L. Stevens⁴, S. A. Krilis ⁵; ¹St. George Hospital, University of New South Wales, Sydney, AUSTRALIA, ²St. George Hospital, University of, Sydney, AUSTRALIA, ³St. Vincent's Hospital, Sydney, AUSTRALIA, ⁴Harvard Medical School and Brigham and Women's Hospital, Boston, MA, ⁵St. George Hospital, Sydney, AUSTRALIA.

196   Trans-basement Membrane Migration of Human Basophils: Role of Matrix Metalloproteinase-9

M. Suzukawa ¹, A. Komiya¹, M. Iikura¹, H. Nagase², C. Yoshimura-Uchiyama¹, H. Yamada¹, H. Kawasaki³, K. Ohta², K. Matsushima¹, K. Hirai¹, K. Yamamoto¹, M. Yamaguchi¹; ¹University of Tokyo Graduate School of Medicine, Bunkyo-ku, Tokyo, JAPAN, ²University of Teikyo School of Medicine, Tokyo, JAPAN, ³University of Tokyo, Bunkyo-ku, Tokyo, JAPAN.

197   NGF-β-Induced Enhancement of FcɛRI-Mediated Activation in Human Basophils is Associated with Reduced SHIP Activity

B. F. Gibbs ^1,2; ¹Medway School of Pharmacy, Chatham Maritime, Kent, UNITED KINGDOM, ²Department of Dermatology, University of Lübeck, GERMANY.

198   Identification and Characterization of Cis-Acting Regulatory Elements of the PAI-1 Gene in Human Mast Cells

C. K. Oh, Z. Ma; Harbor-UCLA Medical Center, Torrance, CA.

199   Mast Cells Stimulate Cytokine Release from Fibroblasts of Asthmatic Airways

L. C. K. Lau, P. N. Sanders, P. H. Howarth, A. F. Walls; Southampton General Hospital, Southampton, UNITED KINGDOM.

200   Role of Mast Cells in the Development of Pulmonary Allergic Inflammation of SHP-1 Deficient Mice

S. Oh, T. Zheng, J. Schroeder, B. Vonakis, O. Choi, Z. Zhu; The Johns Hopkins University, Baltimore, MD.

201   Abnormal Expression of Fcγ Receptors by Human Bone Marrow Mast Cells in Systemic Mastocitosis

L. B. Sanchez-Muñoz ¹, A. Prados¹, R. Nuñez¹, C. Ruiz¹, C. Teodosio², A. Lopez², M. Jara², J. Almeida², A. Orfao², L. Escribano¹; ¹Mast Cell Unit and K. Frank Austen Laboratory, Hospital Ramón y Cajal, Madrid, SPAIN, ²Servicio General de Citometría, Centro de Investigación del Cáncer, Universidad de Salamanca, Salamanca, SPAIN.

202   The 4G/5G-Genotype-Specific Regulation of Plasminogen Activator Inhibitor (PAI)-1 Expression in Human Mast Cells

Z. Ma, C. K. Oh; Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA.

203   Susceptibility to Cow's Milk Allergy (CMA) in C3H/HeJ Mice and Oral Tolerance in BALB/c Mice are Associated With Different Mast Cell Profiles

I. Kirman, R. Du, H. Sampson, X. Li; Mount Sinai School of Medicine, New York, NY.

204   Mature hyphae of Aspergillus fumigatus Induce IgE-Independent Mast Cell Degranulation

M. Urb, P. Pouliot, M. Olivier, D. C. Sheppard; McGill University, Montreal, PQ, CANADA.

205   Leukotriene E4 (LTE4) Is More Potent Than LTD4 For Inducing Cytokine Generation And Proliferation Of Human Mast Cells

S. Paruchuri, J. A. Boyce; Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA.

206   IgE Reversibly Enhances FcɛRI levels on the Surface of Human Skin Mast Cells and Increases Sensitivity to Low Levels of FcɛRI Cross-Linking

G. V. Gomez, S. Jogie-Brahim, M. Shima, L. B. Schwartz; Virginia Commonwealth University, Richmond, VA.

207   Cigarette Smoke Exposure Activates Human Mast Cells (MC) In Vitro

L. H. Bellehsen; Hebrew University of Jerusalem, Jerusalem, ISRAEL.

208   Atrial Natriuretic Peptide is Released from Human Mast Cells following IgE-Mediated Activation

M. C. Glaum, S. Nimal, R. F. Lockey, S. S. Mohapatra; University of South Florida College of Medicine, Tampa, FL.

209   When is a Mouse Basophil not a Basophil?

J. J. Lee, M. P. McGarry; Mayo Clinic Arizona, Scottsdale, AZ.

210   Immunological Response to Cat Allergen: A Comparison of the Effects of Environmental Exposure vs Specific Immunotherapy

C. T. Cady ^1,2, R. J. Harbeck¹, P. C. Giclas¹, J. R. Murphy¹, R. K. Katial¹, R. W. Weber¹, J. C. Cambier^1,2; ¹National Jewish Medical and Research Center, Denver, CO, ²University of Colorado at Denver Health Sciences Center, Denver, CO.

211   Human Lung Mast Cells Express Functional Receptors for Extracellular Adenosine 5′-Diphosphate (ADP)

H. Nishi, A. Pelleg, E. Schulman; Drexel University College of Medicine, Philadelphia, PA.

212   Role of Hydrogen Peroxide in Mycoplasma pneumoniae-induced Mast Cell IL-4 Production

T. P. Atkinson, Y. Dai, L. B. Duffy; Univ of Alabama at Birmingham, Birmingham, AL.

213   Atrial Natriuretic Peptide Can Modulate Human Mast Cell Gene Expression

S. Nimal, M. C. Glaum, P. K. Jena, R. F. Lockey, S. S. Mohapatra; University of South Florida, Tampa, FL.

214   Inhibition of Message for FcɛRI α Chain in RBL Cells Blocks IL-4 Production Induced by Co-Culture with Mycoplasma pneumoniae

D. Luo, Y. Dai, L. B. Duffy, T. P. Atkinson; Univ of Alabama at Birmingham, Birmingham, AL.

Poster Session

2211

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Immunotherapy Mechanisms and Outcomes

215   [Withdrawn]

216   Aggressive Anti-Leukotriene (LT) Prophylaxis Decreases Anaphylaxis Severity during Rush Desensitization (RD)

A. B. Vegh; Puget Sound Allergy Asthma and Imm., Tacoma, WA.

217   Immunomodulator Adjunctive Effects in Treatment of Allergic Diseases

M. Rudenko ¹, L. Siziakina¹, E. Urban¹, L. Du Buske²; ¹Research Institute of Clinical Immunology and Allergology, Rostov-on-Don, RUSSIAN FEDERATION, ²Immunological Research Institute of New England, Gardner, MA.

218   Influence Of Anti-IgE On Nasal Polyps

G. Rasp; Katharinenhospital, Stuttgart, GERMANY.

219   Use of a Multimedia Presentation to Increase Knowledge and Safety of Allergen Immunotherapy

P. Hemmers, S. Amara, B. Silverman, A. T. Schneider; Long Island College Hospital, Brooklyn, NY.

220   Sublingual Immunotherapy with Allergoid Tablets: A Double Blind Placebo Controlled Assay

A. G. Palma-Carlos; Clinical Allergy Immunology Center, Lisbon, PORTUGAL.

221   The Glycerin Induced Large Local Reaction (GILL) study

C. Calabria, M. Tankersley; Wilford Hall Medical Center, San Antonio, TX.

222   Tree Pollen Allergoids in Pollinex Quattro Tree Immunotherapy Reduce the Residual Allergenicity as Assessed with Skin Prick Tests (SPTs)

M. Chudak ¹, P. Patel¹, A. Salapatek¹, K. Jethwa¹, K. J. Fischer von Weikersthal-Drachenberg², J. Amersdorffer²; ¹Allied Research International, Mississauga, ON, CANADA, ²Allergy Therapeutics plc, Worthing, UNITED KINGDOM.

223   Quantitative Measurements of Allergen Specific IgG4 and IgG Antibodies using ImmunoCAP Technology

A. Kober, P. Lundin, L. Söderström, I. Cressy; Phadia AB, Uppsala, SWEDEN.

224   Comparision of Compositional Differences and Relative Potency Between Different Manufacturers of Ragweed Pollen Extracts

P. S. Creticos ¹, S. Balcer-Whaley¹, P. Moldt², O. Pedersen²; ¹Johns Hopkins Asthma and Allergy Center, Baltimore, MD, ²Curalogic, Copenhagen, DENMARK.

225   Systemic Reactions to Percutaneous (P) and Intradermal (ID) Skin Tests (ST)

T. Chacko, M. Glaum, D. Ledford, R. Fox, R. F. Lockey; University of South Florida Collge of Medicine, Tampa, FL.

226   Effects of a Novel Symbiotic, ImmuBalance, as a Food Supplement in Relieving Clinical Symptoms of Japanese Cedar Pollonosis: A Pilot Study

W. PAN ^1,2, Y. Otsuka³; ¹Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, ²Nichimo Co., Ltd., Tokyo, JAPAN, ³Tokorozawa Otolaryngology, Saitama, JAPAN.

227   Segmental Laryngeal Dystonia: A Difficult Differential of Vocal Cord Dysfunction Presenting During Immunotherapy

R. P. Harvey, J. Poole, W. S. Silvers; Allergy Asthma & Immunology Clinic of Colorado, Englewood, CO.

228   Allergy Tests Available over the Internet;‘Caveat emptor!’

A. J. Frew, J. Wade, H. Smith; Brighton & Sussex Medical School, Brighton, UNITED KINGDOM.

229   Allergen-specific Immunotherapy Using A Highly Modified Allergen And The Immunomodulator Polyoxidonium In A Murine Model Of Allergic Asthma

A. A. Babakhin ¹, L. S. Litvin¹, S. M. Andreev¹, O. N. Stetzenko¹, L. N. Voronkova¹, M. R. Khaitov¹, G. G. Barsegyan², I. V. DuBuske³, L. M. DuBuske³; ¹National Research Center - Institute of Immunology, Moscow, RUSSIAN FEDERATION, ²All-Russia Research Center for Molecular Diagnostics and Treatment, Moscow, RUSSIAN FEDERATION, ³Immunology Research Institute of New England, Gardner, MA.

230   Immunotherapy with Dermatophagoides pteronyssinus. Monitoring with Western-blot technique

F. Pineda; DIATER Laboratories, San Martin de la Vega, SPAIN.

231   Aeroallergens in the Valley of Mexico (Frequency)

D. Aguilar, M. I. Rojo, M. A. Bermejo, M. Gonzalez, K. Lopez, K. E. Lopez, T. Sandoval; Juarez Hospital, Mexico, MEXICO.

232   IgE Mediated Sensitization to Weeds Pollen in Saudi Arabia

A. R. Al Frayh; College of Medicine and KKUH, Riyadh, SAUDI ARABIA.

233   A Strategy For Absolute Quantification Of Allergens: Quantification Of Group 2 Isoallergens From A Mixture Of Two Different House Dust Mite Species

U. Seppälä, H. Ipsen, M. D. Spangfort; Research Department, ALK-Abelló, Horsholm, DENMARK.

Poster Session

2212

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Therapy of Allergic Conjunctivitis and Allergic Rhinitis

234   Effect of Montelukast on Collagen Deposition of the Eyes in a Murine Model of Chronic Allergic Eye Disease

E. Marzo, Z. Ma, C. Oh; Harbor UCLA, Torrance, CA.

235   A Single-Center, Double Masked, Randomized, Placebo Controlled Study to Evaluate the Efficacy of Multiple Doses of 10 mg Montelukast Sodium (Singulair®) on the Signs and Symptoms of Allergic Conjunctivitis Using the Conjunctival Allergen Challenge (CAC) Model

P. J. Gomes, M. B. Abelson; Ophthalmic Research Associates, North Andover, MA.

236   Intravenous Immune Globulin (IVIG) in the Treatment of Ocular-Cicatricial Pemphigoid (OCP)

J. A. Lagos, S. F. Kemp, G. D. Marshall; University of Mississippi Medical Center, Jackson, MS.

237   Ocular Symptoms of Seasonal Allergic Rhinitis Can Be Treated Effectively With An Inhaled Corticosteroid (Mometasone Furoate Nasal Spray)

L. Bielory ¹, M. Danzig², D. Gates²; ¹UMDNJ-New Jersey Medical School, Newark, NJ, ²Schering-Plough Research Institute, Kenilworth, NJ.

238   Total Ocular Symptom Scores in Patients With Seasonal Allergic Rhinitis are Reduced With Mometasone Furoate Nasal Spray

G. Sussman ¹, M. Danzig², D. Gates²; ¹University of Toronto Faculty of Medicine, Toronto, ON, CANADA, ²Schering-Plough Research Institute, Kenilworth, NJ.

239   Mometasone Furoate Nasal Spray Improves Nasal and Ocular Symptoms of Seasonal Allergic Rhinitis in Adolescent Patients

R. Anolik ¹, D. Pearlman², M. Danzig³, D. Gates³; ¹Allergy & Asthma Specialists, PC, Blue Bell, PA, ²Colorado Allergy and Asthma Centers, PC, Denver, CO, ³Schering-Plough Research Institute, Kenilworth, NJ.

240   Mometasone Furoate Improves Total Ocular Symptom Score in Patients With Allergic Rhinitis

J. Hébert ¹, M. Danzig², D. Gates²; ¹Université Laval Faculté de Médecine, Québec City, PQ, CANADA, ²Schering-Plough Research Institute, Kenilworth, NJ.

241   Safety and Tolerability of Repeated Nasal Allergen Challenges

I. Hussain ¹, P. Sayre¹, F. Romero², W. W. Busse³, J. N. Kline⁴, T. B. Casale²; ¹University of California San Francisco, San Francisco, CA, ²Creighton University, Omaha, NE, ³University of Wisconsin, Madison, WI, ⁴University of Iowa, Iowa City, IA.

242   Comparative Responses to Nasal Allergen Challenge in Allergic Rhinitic Subjects With or Without Asthma

M. Rousseau; Centre de recherche de l'hôpital Laval, Québec, PQ, CANADA.

243   Effect of Antibiotic Treatment on Nasal and Maxillary Sinus Nitric Oxide in Patients with Acute Bacterial Sinusitis

M. J. Lanz, S. Prendes, G. Toledo, C. M. Ferrer; Allergy, Asthma, Rhinitis & Sinusitis CRC, Coral Gables, FL.

244   Criterion for Eosinophilic Nasal Polyp: A Clinicopathologic Correlation

C. Rhee, W. Jeong, J. Kim, S. Kim, T. Won, Y. Kim, C. Lee, S. Cho, Y. Min; Seoul National University College of Medicine, Seoul, REPUBLIC OF KOREA.

245   Efficacy of Mometasone Furoate Nasal Spray in Seasonal Allergic Rhinitis According to Baseline Symptom Severity

M. J. Derebery; House Clinic, Los Angeles, CA.

246   Evaluation Of Respiratory Pressure Meter In Atopic And Non-atopic Rhinitis

Y. Park ¹, H. Park², J. Lee³; ¹Department of Pediatrics, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, Konkuk University Hospital, Seoul, REPUBLIC OF KOREA, ³Department of Pediatrics, Samsung Masan Hospital, Sungkyunkwan University School of Medicine, Masan, REPUBLIC OF KOREA.

247   Use of Acoustic Rhinometry In Allergic Children

C. Nunes, S. Ladeira; Center of Allergy of Algarve, Portimao, PORTUGAL.

248   Improvement of Symptoms in Children 6 to 12 Years With Allergic Rhinitis Seen With Desloratadine Therapy With or Without Concomitant Corticosteroids

P. Tassinari ¹, N. R. Suárez², J. Centeno³, J. Vergara Velásquez⁴, H. Aguirre-Mariscal⁵, S. N. Gonzàlez Dìaz⁶, A. Fernández de Córdova Jerves⁷; ¹Universidad Central de Venezuela, Caracas, VENEZUELA, ²Policlínica Metropolitana, Caracas, VENEZUELA, ³Universidad Peruana Cayetano Heredia, Lima, PERU, ⁴Centro Especializado San Fernando, Panama City, PANAMA, ⁵Hospital Angeles Pedregal, Mexico City, MEXICO, ⁶Hospital Universitario, Monterrey, MEXICO, ⁷Hospital Universitario del Rio, Cuenca, ECUADOR.

249   Improved Symptom Relief and Quality of Life With Desloratadine in Pollen-Induced Allergic Rhinitis

D. Dumitrascu; University of Medicine and Pharmacy Iuliu Hatieganu, Cluj Napoca, ROMANIA.

250   Efficacy and Safety of Desloratadine in Combination with Mometasone Furoate in Patients With Moderate-to-Severe SAR

G. Grevers ¹, B. Karmann²; ¹Nose and Sinus Center, Starnberg, GERMANY, ²Medical Affairs, Essex Pharma GmbH, Munich, GERMANY.

251   Mometasone Furoate Nasal Spray Rapidly and Enduringly Relieves Nasal Congestion and Other Symptoms of Seasonal Allergic Rhinitis

G. N. Gross ¹, M. R. Danzig², D. Gates²; ¹Dallas Allergy and Asthma Center, Dallas, TX, ²Schering-Plough Research Institute, Kenilworth, NJ.

252   Desloratadine Treatment Improves Symptoms in Patients With Seasonal Allergic Rhinitis

I. Braverman ¹, M. Beiser², Z. Gilad³; ¹Hillel Yaffe Medical Center, Hadera, ISRAEL, ²The Tel Aviv Sourasky Medical Center, Tel Aviv, ISRAEL, ³Schering-Plough Israel AG, Petach Tikva, ISRAEL.

Poster Session

2213

Saturday, February 24, 2007

9:45 AM - 10:45 AM

Allied Health Poster Session

253   Respiratory Protection and Incident Skin Test Sensitivity Among Laboratory Mouse Workers

J. M. Curtin-Brosnan ¹, P. A. Eggleston¹, B. J. Paigen², E. A. O'Neil², K. A. Hagberg², E. C. Matsui¹; ¹Johns Hopkins University, Baltimore, MD, ²The Jackson Laboratory, Bar Harbor, ME.

254   Once Daily Fluticasone Furoate^∗ Nasal Spray (FFNS), a Novel Enhanced Affinity Steroid, Provides 24-hour Relief for the Nasal Symptoms of Perennial Allergic Rhinitis (PAR)

R. Nathan ¹, W. Berger², W. Yang³, A. Cheema⁴, M. J. Silvey⁵, W. Wu⁵, M. Faris⁵, E. Philpot⁵; ¹Asthma & Allergy Associates, P.C., Colorado Springs, CO, ²Southern California Research, Mission Viejo, CA, ³Allergy & Asthma Research Centre, Ottawa, ON, CANADA, ⁴Private Practice, Mississauga, ON, CANADA, ⁵GlaxoSmithKline, Research Triangle Park, NC.

255   Identification Of Ige-mediated Drug Allergy In Patients With Adverse Drug Reactions Categorized By World Health Organization-the Uppsala Monitoring Centre (who-umc) System

C. Tantikul, N. Dhana, K. Jongjareornprasert, S. Rithikot, N. Visitsunthorn, P. Vichyanond, O. Jirapongsananuruk; Siriraj Hospital, Bangkok, THAILAND.

256   A Survey of Community Physicians' Perceptions Related to Asthma Education

C. A. Gillespie, A. B. Becker; Health Sciences Centre, Winnipeg, MB, CANADA.

257   Improving Asthma Communication With Inner City Parents: Does It Work?

A. Butz ¹, C. Land¹, J. Walker¹, M. E. Bollinger²; ¹Johns Hopkins University, Baltimore, MD, ²University of Maryland, Baltimore, MD.

258   Innovative Reporting of Penicillin Allergy in an Integrated Electronic Medical Record

P. J. Markus, D. M. Erickson, J. T. C. Li, R. R. Bessette, J. E. Rueter, D. R. Osmon, N. J. Larson, K. E. Kloos, M. A. Park; Mayo Clinic and Foundation, Rochester, MN.

259   Unusual Side Effect Of Treatment To Large Local Reaction To Immunotherapy

C. W. Wagner ^1,2, A. G. Mery¹; ¹Allergy and Asthma Associates, Houston, TX, ²Texas Woman's University, Houston, TX.

260   Comparison Of Efficacy Of Once Daily Zyrtec^R(cetirizine), Cetrizin^R(cetirizine), Desloratadine And Placebo: Suppressive Effects On Allergen And Histamine Induced Wheal And Flare Responses In Allergic Rhinitis Patients

A. Sukkul, K. Ruxrungtham; Chulalongkorn Hospital, Bangkok, THAILAND.

261   Pyrimethamine Desensitization In Cerebral Toxoplasmosis And Aids

E. Gonzalez, A. Henriquez, A. Losada, B. Huertas, J. Gonzalez, P. Berges, E. Alvarez; Servicio de Alergia Hospital Ramon y Cajal, Madrid, SPAIN.

262   Evolution of Asthma Population Management

C. A. Martin ¹, C. Tacinas², C. Lamb², K. Baldwin², S. Hay², S. Heermann², J. Hoban², V. Perry², B. J. Spiecher²; ¹Kaiser Permanente, Westminster, CO, ²Kaiser Permanente, Denver, CO.

263   Evaluation of Penicillin Allergy in an Allergy Immunology Practice

C. S. Wright; Allergy Medical Clinic, Los Angeles, CA.

264   A Comparison of Peak Pollen Times in the Missoula Valley from 1978 and 2006

K. L. Crispen ¹, D. N. Gillespie², T. J. Ward³, A. Holian⁴; ¹University of Montana Center for Environmeantal Health Sciences, Missoula, MT, ²Allergist, Missoula, MT, ³University of Montana Center for Environmental Health Sciences, Missoula, MT, ⁴University of Montana Center for Environmental Health Sciences, Missoula, MT.

265   Frontal Sinusitis Complicated by an Epidural Abscess and Seizures

D. C. Wirth, S. B. Tanner; Vanderbilt Univeristy Medical Center: Asthma, Sinus, Allergy Program, Nashville, TN.

266   Respiratory Health of Kentucky Farm Children

P. V. Burkhart ¹, S. R. Browning², S. Westneat³, C. A. Knox⁴, D. Abshire¹; ¹University Of Kentucky, Lexington, KY, ²University Of Kentucky College of Public Health, Lexington, KY, ³University Of Kentucky College of Nursing, Lexington, KY, ⁴Kosair Children's Hospital, Louisville, KY.

267   Do Parents Follow Breastfeeding And Weaning Recommendations Given By The Pediatric Nurses? A Study With Emphasis On Introduction Of Cow's Milk Protein In Allergy Risk Families

A. Mikkelsen ¹, L. Rinné-Ljungqvist², M. P. Borres, Sr.³, J. van Odijk⁴; ¹Dep. of Primary Health Care, Göteborg, SWEDEN, ²Primary Health Care Services of Partille, Partille, SWEDEN, ³Dep. of Pediatrics, Sahlgrenska Academy, Göteborg University, Göteborg, SWEDEN, ⁴Dep. of Clinical Nutrition, Sahlgrenska Academy, Göteborg University, Göteborg, SWEDEN.

Oral Abstract Session

2601

Saturday, February 24, 2007

2:00 PM - 3:15 PM

Allergen Sensitization and Asthma

268   Effect Of Age And Aeroallergen Sensitivities On Acquisition Of Aeroallergen Sensitivities Among Children With Asthma In The Childhood Asthma Management Program (CAMP)

K. A. DeMuth ¹, R. Strunk¹, G. Bloomberg¹, A. Liu², L. Bacharier¹; ¹Washington University in St. Louis, Saint Louis, MO, ²National Jewish Hospital Medical & Research., Boulder, CO.

269   Asthma at Age 6 is Associated with an Early and Variable Pattern of Allergic Sensitization in Childhood

C. J. Tisler ¹, K. A. Roberg¹, E. L. Anderson¹, L. E. Salazar¹, R. A. Grabher¹, D. F. DaSilva¹, T. E. Pappas¹, K. Sullivan Dillie¹, R. E. Gangnon², M. D. Evans², J. E. Gern¹, R. F. Lemanske, Jr.¹; ¹University of Wisconsin School of Medicine and Public Health, Madison, WI, ²University of Wisconsin-Population Health Sciences Biostatistics and Medical Informatics, Madison, WI.

270   Allergen Sensitization as a Predictor of Wheezing Phenotype at Age Six Years

C. M. Virnig, K. Roberg, E. Anderson, L. E. P. Salazar, R. A. Grabher, C. Tisler, D. F. DaSilva, T. E. Pappas, K. Sullivan Dillie, M. D. Evans, R. E. Gargnon, J. E. Gern, R. F. Lemanske, Jr.; UW School of Medicine and Public Health, Madison, WI.

271   Association Of The Genetic Polymorphism Of The Surfactant Protein (SP)-D With Mite-sensitization In Childhood Asthma

M. Lei ^1,2, W. Dai¹, C. Tan¹, J. Wang¹; ¹Dept of Ped, College of Medicine, National Cheng Kung University, Tainan, TAIWAN, ²Institude of molecular medicine, Tainan, TAIWAN.

272   Effect of a Single Nucleotide Polymorphism in the Surfactant Protein D Gene on Atopy and Asthma Susceptibility

E. B. Brandt, N. Wang, E. Grube, M. Stevenson, G. K. Khurana Hershey, M. E. Rothenberg; Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

273   Allergen and Endotoxin Exposure, Infection, and Breastfeeding in Early Life, and Recurrent Wheezing in Infants: 18-month Follow-up of a Cohort Study

V. E. V. Rullo ¹, D. Solé¹, V. Valente¹, C. Nakamura¹, A. S. Zampolo², L. K. Arruda², R. C. Cardoso³, F. J. Nóbrega⁴, C. K. Naspitz¹; ¹Pediatrics, Federal University of São Paulo, São Paulo, BRAZIL, ²Medicine, School of Medicine of Ribeirão Preto-USP, Ribeirão Preto, BRAZIL, ³School of Public Health-USP, São Paulo, BRAZIL, ⁴Pediatrics, Albert Einstein Hospital, São Paulo, BRAZIL.

Oral Abstract Session

2602

Saturday, February 24, 2007

2:00 PM - 3:15 PM

Highlights in Immunodeficiency 2007

274   T-B+NK+ Severe Combined Immunodeficiency Caused by Complete Deficiency of the CD3zeta Subunit of the T Cell Antigen Receptor Complex

J. L. Roberts ¹, J. P. H. Lauritsen², M. Cooney¹, R. E. Parrott¹, E. O. Sajaroff¹, C. M. Win¹, M. D. Keller¹, J. H. Carpenter¹, M. Sarzotti¹, X. Zhong¹, D. L. Wiest², R. H. Bucley¹; ¹Duke University Medical Center, Durham, NC, ²Fox Chase Cancer Center, Philadelphia, PA.

275   Lysophosphatidylserine (Lyso-PS), a Signaling Phospholipid, is Deficient in Models of Chronic Granulomatous Disease (CGD)

D. L. Bratton ¹, K. Zemski-Berry², R. C. Murphy³, P. M. Henson¹, S. C. Frasch¹; ¹National Jewish Medical and Research Center, Denver, CO, ²Univeristy of Colorado at Denver and Health Science Center, Aurora, CO, ³University of Colorado at Denver and Health Science Center, Aurora, CO.

276   Immunologic and Clinical Features of 21 Amish Patients with Cartilage-Hair Hypoplasia

N. L. Rider ¹, D. Morton², K. A. Strauss²; ¹Penn State Milton S. Hershey Medical Center, Hershey, PA, ²The Clinic for Special Children, Strasburg, PA.

277   Lymphocyte Proliferation to Antigens Develops Over Time in Partial DiGeorge Syndrome

V. S. Kancherla, A. P. Reddy, L. M. Noroski, J. Chinen, H. W. Yeh, C. M. Davis; Baylor College of Medicine, Houston, TX.

278   Association Between Mannose-Binding Lectin Deficiency and Immunoglobulin Subclass 4 Deficiency in Children with Recurrent Infections

M. M. Dowd ¹, N. Tangsinmankong², D. D. Siri², A. S. Hartel², K. S. Brauer¹, I. N. Umeh¹, N. K. Day², J. W. Sleasman²; ¹Department of Pediatrics, University of South Florida College of Medicine, St. Petersburg, FL, ²Division of Allergy and Immunology, University of South Florida College of Medicine, St. Petersburg, FL.

279   Specialist Physician Perspectives On Primary Immunodeficiency Diseases: A 2006 Survey Of The AAAAI Membership

J. S. Orange ¹, J. Boyle²; ¹Children's Hospital of Philadelphia, Philadelphia, PA, ²Immune Deficiency Foundation, Towson, MD.

Oral Abstract Session

2603

Saturday, February 24, 2007

2:00 PM - 3:15 PM

Predictors of Response and Methods of Improving Asthma

280   Monocyte Chemotactic Protein-4 (MCP-4; CCL-13) and the CC chemokine Receptor 3 (CCR3) in Sputum of Asthmatic Children

Y. M. El-Gamal ¹, N. M. Heshmat¹, K. S. Awwad¹, M. H. M. Ezzat¹, M. M. Abd Al-Aziz², Z. M. El-Gabbas¹; ¹Department of Pediatrics, Faculty of Medicine, Ain Shams University, Cairo, EGYPT, ²Department of Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo, EGYPT.

281   Exhaled Nitric Oxide as a Predictor of Response to Anti-inflammatory Treatment in Asthma

A. Michils, S. Baldassarre, A. Van Muylem; Erasme University Hospital, Brussels, BELGIUM.

282   Impact and Use of Asthma Control Test (ACT™) on Healthcare Resource Use (HCRU) in a Managed Care (MC) Setting

J. R. CarranzaRosenzweig, P. M. Jhingran, A. A. Dalal; GlaxoSmithkline, RTP, NC.

283   Improving Asthma Care in Disadvantaged Elderly: A Randomized, Controlled Trial Using Telephone Intervention Conducted by Non-Medically Trained Personnel

R. R. Patel, W. L. Gray, C. A. Saltoun, L. C. Grammer; Department of Medicine, Division of Allergy-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL.

284   Longitudinal Patterns of Predominant Disease Activity (PDA) in Pediatric Patients Receiving Care in an Inner City Asthma Disease Management Program: The Breathmobile Program™

L. Scott ¹, B. Nichols¹, K. Y. Kwong¹, T. Morphew², L. T. Clement¹, F. Lifson², C. A. Jones¹; ¹LAC+USC, Los Angeles, CA, ²Southern California Chapter of the Asthma and Allergy Foundation of America (AAFA), Los Angeles, CA.

285   Development and Validation of ‘Asthma Control in Paediatrics’ Questionnaire (CAN)

M. Ibero ¹, X. Badia², N. Cobos³, J. Garde⁴, E. G. Pérez-Yarza⁵, J. Villa⁶, C. Badiola⁷; ¹Hospital de Terrassa, Terrassa, SPAIN, ²Healt Outcomes Research Europe, Barcelona, SPAIN, ³Hospital Vall d'Hebró, Barcelona, SPAIN, ⁴Hospital General d'Elx, Elx, SPAIN, ⁵Hospital de Donostia, San Sebastián, SPAIN, ⁶Hospital del Niño Jesús, Madrid, SPAIN, ⁷Medical Department GSK, Madrid, SPAIN.

Oral Abstract Session

2604

Saturday, February 24, 2007

2:00 PM - 3:15 PM

Food Allergies: Natural History, Diagnosis and Treatment

286   The Natural History of Cow's Milk Allergy (CMA)

J. M. Skripak; Johns Hopkins Medical School, Baltimore, MD.

287   Clinical Manifestations and Natural History of Egg Allergy in Infants and Children

R. G. Heine ^1,2, N. Laske¹, D. J. Hill²; ¹Royal Children's Hospital, Melbourne, AUSTRALIA, ²Murdoch Childrens Research Institute, Melbourne, AUSTRALIA.

288   The Utility of Combining Skin Prick and Specific IgE Antibody Testing as a Predictor of Clinical Reactivity to Milk, Egg, and Peanut

D. R. Naimi, N. M. Paranich, J. M. Spergel, J. L. Beausoleil; The Children's Hospital of Philadelphia, Philadelphia, PA.

289   Consumer Awareness and Response Following the Food Allergen Labeling and Consumer Protection Act (FALCPA)

H. Lemon-Mule ¹, T. J. Furlong², S. H. Sicherer¹; ¹Mt Sinai School Of Medicine, New York, NY, ²Food Allergy & Anaphylaxis Network, Fairfax, VA.

290   Preliminary Support for a Group Intervention for Children with Food Allergy and Their Parents

J. S. LeBovidge, K. G. Timmons, C. Rich, A. Rosenstock, K. Fowler, L. C. Schneider; Children's Hospital Boston, Boston, MA.

291   Oral Desensitization Therpy In Children With Egg Allergy

M. Akashi, M. Narita, A. Saito, T. Suda, I. Nomura, A. Akasawa, Y. Ohya; National Center for Child Health and Development, Tokyo, JAPAN.

Oral Abstract Session

2605

Saturday, February 24, 2007

2:00 PM - 3:15 PM

Underserved Population

292   Prevalence of Obesity in Severe Asthma Differs by the Anthropometric Measure

S. M. Musaad ^1,2, G. K. Hershey²; ¹University of Cincinnati, Cincinnati, OH, ²Cincinnati Childrens Hospital Medical Center, Cincinnati, OH.

293   The Role of Allergy Treatment in Asthma Management among Urban Children

J. A. Stingone, L. Claudio; Mount Sinai School of Medicine, New York, NY.

294   Utilization of Non-Traditional and Alternative Therapies (CAM) in Inner City Under-Served Children with Asthma

K. Tai ¹, M. Tsoukleris^1,2, V. Hsu¹, I. H. Zuckerman¹, M. E. Bollinger², K. Mudd³, M. Donithan⁴, A. M. Butz³; ¹University of Maryland School of Pharmacy, Baltimore, MD, ²University of Maryland School of Medicine, Baltimore, MD, ³The Johns Hopkins University School of Medicine, Baltimore, MD, ⁴The Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD.

295   Patterns of Asthma Mortality in Ohio: 1999-2003 Compared with 1990-98

D. R. Stukus ¹, N. Nock², D. M. Lang¹; ¹The Cleveland Clinic, Cleveland, OH, ²Case Western Reserve University, Cleveland, OH.

296   Characteristics and Outcomes of Asthmatics Who Leave Against Medical Advice (AMA)

A. P. Baptist, J. Ager, M. Massanari; Wayne State University, Detroit, MI.

297   Population Density and Race as Factors in Asthma Mortality

N. M. Lebak, L. B. Schwartz; Medical College of Virginia, Virginia Commonwealth University, Richmond, VA.

Oral Abstract Session

2606

Saturday, February 24, 2007

2:00 PM - 3:15 PM

Allergic Inflammation

298   Effects of Lipoxin A4 (LX) on Glucocorticoid Receptor (gr) Function

J. M. Terasaki ¹, N. N. Bulayeva¹, B. D. Levy², W. J. Calhoun¹; ¹Division of Allergy, Pulmonary, Immunology, CCM, & Sleep (APICS), University of Texas Medical Branch, Galveston, TX, ²Department of Internal Medicine and Center for Experimental Therapeutics and Reperfusion Injury, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

299   Blockage of IL-10 Modulates Airway Inflammation-Associated Eosinophilia And IL-4 Levels in C57Bl6 Mice

Y. Ogawa, E. A. Duru, J. L. Parks, IV, W. J. Calhoun, B. T. Ameredes; University of Texas Medical Branch, Galveston, TX.

300   CysLT1 Receptor Signaling Induces Transcriptional Upregulation of Proprotein Convertase Furin Expression: Potential Implications in Airway Remodeling

M. Rola-Pleszczynski, C. Thompson, S. McMahon, Y. Bossé, C. M. Dubois, J. Stankova; Université de Sherbrooke, Sherbrooke, PQ, CANADA.

301   Fractional Exhaled Nitric Oxide (FeNO) is Elevated in School Aged Children who have Culture-Documented Frequent Viral Respiratory Illnesses during Infancy

L. E. Salazar, M. D. Evans, E. L. Anderson, D. F. DaSilva, R. A. Grabher, T. E. Pappas, K. A. Roberg, K. Sullivan Dillie, C. J. Tisler, R. E. Gangnon, J. E. Gern, R. F. Lemanske, Jr.; University of Wisconsin-Madison, Madison, WI.

302   A Anisakis Simplex Homolog of Macrophage Migration Inhibitory Factor Inhibits Allergic Airway Responses in Mice

H. Park ¹, J. Lee¹, K. Kim¹, H. Jeong², Y. Jeong³, J. Jeong⁴, Y. Kim¹, M. Lee¹, S. Park¹, H. Yu²; ¹Internal Medicine, Pusan National University School of Medicine, Busan, REPUBLIC OF KOREA, ²Department of Parasitology, Pusan National University School of Medicine, Busan, REPUBLIC OF KOREA, ³Internal Medicine, Gyeonsang National University School of Medicine, Jinju, REPUBLIC OF KOREA, ⁴Internal Medicine, Iilsan Paik Hospital, Kyungki-do, REPUBLIC OF KOREA.

303   Sensitization to Multiple Allergens Breaks Through Tolerance and Establishes Chronic Asthma That is Unresponsive to Anti-Cytokine Therapy

R. Alam, N. Goplen, Q. Liang, S. Rozario, Y. Morimoto, M. Gorska; National Jewish Medical and Research Center, Denver, CO.

Oral Abstract Session

2607

Saturday, February 24, 2007

2:00 PM - 3:15 PM

Allergen Immunotherapy: From Bench to Bedside

304   Stability of Protease Rich Periplaneta americana Allergen Extract During Storage: Formulating Preservatives to Enhance Shelf life

V. Thangam Sudha ^1,2, N. Arora¹, S. N. Gaur³, B. P. Singh¹; ¹Institute of Genomics and Integrative Biology, Delhi, INDIA, ²Department of Biotechnology, University of Pune, Pune, INDIA, ³V. P. Chest Institute, Delhi, INDIA.

305   Usefulness Of Specific Ige Determination To Recombinant Grass Pollen Allergens (cap-feia) In Pollinic Patients

J. M. de la Borbolla, R. Escudero, J. Antón, M. J. Goikoetxea, M. L. Sanz, M. Ferrer; University Clinic, School of Medicine, University of Navarra, Pamplona, SPAIN.

306   Correlation Between SIT Induced Inhibition of IgE Binding, Histamine Release and Facilitated Allergen Presentation

P. A. Würtzen ¹, G. Lund¹, J. Holm¹, M. Arvidsson², K. Lund¹, S. Rak³, H. Ipsen¹; ¹ALK-Abello, Hørsholm, DENMARK, ²Department of Medical Sciences, Clinical Chemistry, University Hospital, Uppsala, SWEDEN, ³Asthma and Allergy Research Group, Department of Respiratory Medicine and Allergology, Sahlgrenska University Hospital, Goteborg, SWEDEN.

307   Safety and Efficacy of the Novel Vaccine TOLAMBA™ in Ragweed Allergic Adults, a Dose Finding Study

D. I. Bernstein ¹, N. Segall², A. Nayak³, T. Casale⁴, P. Korenblatt⁵, E. Martins⁶; ¹Bernstein Allergy Group, Cincinnati, OH, ²Clinical Research of Atlanta, Stockbridge, GA, ³Sneeze, Wheeze and Itch Associates, Normal, IL, ⁴Creighton U., Omaha, NE, ⁵Clinical Re-search Center, St. Louis, MO, ⁶Dynavax Technologies, Berkeley, CA.

308   Venom Immunotherapy (VIT) Reduces Large Local Reactions (LLR) to Insect Stings

D. Kelly ¹, D. B. K. Golden¹, R. G. Hamilton¹, T. J. Craig²; ¹Johns Hopkins University, Baltimore, MD, ²Penn State Hershey Medical Center, Hershey, PA.

309   Prolonged Pre-seasonal Treatment Phase with Sublingual Immunotherapy Increases Clinical Efficacy

M. A. Calderon ¹, A. O. Birk², J. S. Andersen², S. R. Durham¹; ¹Imperial College, National Heart and Lung Institute, London, UNITED KINGDOM, ²ALK-Abelló, Hörsholm, DENMARK.

Oral Abstract Session

2608

Saturday, February 24, 2007

2:00 PM - 3:15 PM

Allied Health Oral Abstracts Session

310   Predicting Outcome of Repeated Oral Food Challenges

K. E. Mudd, M. Paterakis, J. Curtin-Brosnan, R. A. Wood; Johns Hopkins University, School of Medicine, Baltimore, MD.

311   Analysis of a System to Provide Consistent Care of Patients with Fatality-Prone Asthma (FPA)

L. C. Kertz, R. C. Strunk, L. B. Bacharier; Washington University School of Medicine, St. Louis, MO.

312   The Integration of Web-based Asthma Education with Nurse Case Management

K. Kelly-Shanovich ¹, A. D. Pulvermacher¹, C. A. Sorkness², A. Bhattacharya³, D. H. Gustafson¹; ¹Center for Health Enhancement Systems Studies, University of Wisconsin - Madison, Madison, WI, ²Schools of Pharmacy and Medicine, University of Wisconsin - Madison, Madison, WI, ³Center for the Study of Cultural Diversity in Healthcare, University of Wisconsin - Madison, Madison, WI.

313   A Needs Assessment Project to Enhance Patient and Provider Asthma Communication

P. M. Fritz, F. L. Schottenfeld, C. Spampinato, G. Gallinger; NYS Dept of Health, Troy, NY.

314   The Impact of Home Visits on Retention in a Low-Income School Based Mobile Asthma Clinic

C. M. Carcel ¹, S. Amaro¹, F. Sowa², T. Morphew³, S. P. Galant¹; ¹Children's Hospital of Orange County, Orange, CA, ²Latino Health Access, Santa Ana, CA, ³AAFA, Los Angeles, CA.

315   Does Use of Asthma Controllers Really Indicate Asthma “Control?”

C. L. Vibbert ¹, A. Butz², M. Tsoukleris³, V. D. Hsu³, M. E. Bollinger¹; ¹University of Maryland School of Medicine, Baltimore, MD, ²Johns Hopkins University School of Medicine, Baltimore, MD, ³University of Maryland School of Pharmacy, Baltimore, MD.

Poster Session

3201

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Asthma Diagnosis

316   Sputum Mediators in Children with Mild Persistent Asthma Indicate Immune Dysregulation and Correlate with Lower Lung Function

N. Patel ¹, A. M. Schiltz¹, R. Harbeck¹, R. A. Covar^1,2, S. M. Wood³, S. J. DeMichele³, E. W. Gelfand^1,2, S. J. Szefler^1,2, A. H. Liu^1,2; ¹National Jewish Medical and Research Center, Denver, CO, ²University of Colorado School of Medicine, Denver, CO, ³Ross Products Division/Abbott Laboratories, Columbus, OH.

317   Clinical Implication of Vascular Endothelial Growth Factor (VEGF) in Childhood Asthma

K. Kim ¹, E. Kim¹, J. Park¹, G. Jang², C. Kim³, H. Lee³, M. Sohn¹, K. Kim¹; ¹Department of Pediatrics and Institute of Allergy, Severance Children's Hospital, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, NHIC Ilsan Hospital, Goyang, REPUBLIC OF KOREA, ³Department of Pediatrics, Kwandong University, Goyang, REPUBLIC OF KOREA.

318   The Predictive Power of Frequent eNO Measurements in Patients with Asthma

J. D. Wolfe ¹, D. M. Dreon², B. R. Parikh², E. E. Hutchins², M. N. Bates³; ¹Asthma and Allergy Associates of Northern California, San Jose, CA, ²Aperon Biosystems Corp., Menlo Park, CA, ³University of California - Berkeley, Berkeley, CA.

319   Exhaled Nitric Oxide and Pulmonary Function Tests in Children with Asthma

S. Choi ¹, H. Koh², C. Bae², Y. Rha²; ¹Department of Pediatrics, College of Medicine, Seoul National University, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, REPUBLIC OF KOREA.

320   Diagnostic Value of Eosinophil Cationic Protein (ECP) in Children with Asthma Undergoing Food Challenges

A. Krogulska, K. Wasowska-Królikowska, J. Dynowski; Medical University Lodz, Poland, Lodz, POLAND.

321   Longitudinal Changes in Bronchial Hyperresponsiveness and Exposure to High Levels of Domestic Pet Allergens

S. J. Fowler ^1,2, N. Truman¹, A. Simpson¹, A. A. Woodcock¹, S. J. Langley¹, A. Custovic¹; ¹University of Manchester, Manchester, UNITED KINGDOM, ²Lancashire Teaching Hospitals, Preston, UNITED KINGDOM.

322   Roc Curve Analysis Of Serum-specific Ige Levels To Predict Airway Reactivity To Dog Allergens In Asthmatic Subjects

A. Matito, S. Blanco, P. Gajate, L. Martín, R. Vives, C. Ortega, C. Fernandez; Hospital 12 de Octubre, Madrid, Spain.

323   Correlation between Clinical Parameters of Asthma and Airway Dimension, Air Trapping and Airway Collapsibility Measured by Volumetric Inspiration and Expiration CT

H. Moon ^1,2, T. Kim^1,2, E. Chae^3,2, N. Kim³, Y. Lee³, C. Park^1,2, B. Yoo¹, J. Seo^3,2, Y. Cho^1,2; ¹Department of Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, REPUBLIC OF KOREA, ²Clinical Research Center for Chronic Obstructive Airway Disease, Asan Medical Center, University of Ulsan College of Medicine, Seoul, REPUBLIC OF KOREA, ³Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, REPUBLIC OF KOREA.

324   Effect of Emergency Room Treatment of Acute Asthma on Plasma Levels of Complement Split Products

D. Dure ¹, I. Kalampokis¹, E. Monk, Jr.¹, C. Charlot¹, E. Gilbert¹, M. Nowakowski¹, R. Sinert², R. Joks¹; ¹Center for Allergy and Asthma Research, SUNY, Brooklyn, NY, ²Kings County Hospital Center, Brooklyn, NY.

325   Standard Range Of Peak Expiratory Flow Rate Of Korean Children In Seoul

W. H. Seo ¹, H. K. Shin¹, S. H. Ahn², S. H. Park², K. M. Ahn², S. I. Lee²; ¹College of Medicine, Korea University, Seoul, REPUBLIC OF KOREA, ²Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, REPUBLIC OF KOREA.

326   Airflow Obstruction Of Adolescent Asthmatics Without Current Respiratory Symptoms

H. Nishimura ¹, K. Tokuyama², M. Suzuki¹, T. Mizuno³, H. Koyama³, H. Arakawa³, H. Mochizuki³, A. Morikawa³; ¹Tone Central Hospital, Numata, JAPAN, ²Takasaki Univ. of health and Welfare, Takasaki, JAPAN, ³Gunma Univ., Maebashi, JAPAN.

327   Dynamic Oxygen-Enhanced Magnetic Resonance Imaging is Not Useful in Assessing Severity or Airway Inflammation in Asthmatic Children

T. F. Leung ¹, W. C. W. Chu², C. W. Y. Kam¹, D. T. Yeung², C. Y. Li¹, G. W. K. Wong¹, P. C. Ng¹; ¹Department of Pediatrics, The Chinese University of Hong Kong, Hong Kong, HONG KONG, ²Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Hong Kong, HONG KONG.

328   Measurement of Specific IgE Levels in Korean Allergic Disease Children by Using CAP system

J. Lee ¹, J. Jung², J. Kim³, C. Kim⁴, Y. Park⁵; ¹Masan samsung hospital, Masan si, REPUBLIC OF KOREA, ²Dong A university, Busan, REPUBLIC OF KOREA, ³Ulsan university, Ulsan, REPUBLIC OF KOREA, ⁴Kwan Dong University, Seoul, REPUBLIC OF KOREA, ⁵Konkuk university, Seoul, REPUBLIC OF KOREA.

329   The Impact of Electronic Medical Records on Timeliness of Diagnosis of Asthma

K. H. Yoo ¹, S. Bagniewski², A. L. Weaver², S. V. Pankrantz², R. M. Jacobson², Y. J. Juhn²; ¹Mayo Clinic/Konkuk University, Rochester, MN, ²Mayo Clinic, Rochester, MN.

330   Cutaneous Sensitization to Indoor allergens in children with Asthma and Rhinitis in Chiclayo, Peru

F. V. Maticorena Agramonte, L. Suarez, W. Presentacion; Hospital Belen, Chiclayo, PERU.

331   Cell-specific Activation of ERK1/2 and p38 MAPK in Airway Biopsy Samples from Asthmatic patients

Q. Liang, S. Balzar, S. Wenzel, M. Gorska, R. Alam; National Jewish Medical and Research Center, Denver, CO.

332   The Severity of Historical ASA/NSAID-Induced Asthma Attacks Does Not Correlate with Severity of Asthma Induced During Oral ASA Challenges

A. N. Williams, R. A. Simon, K. M. Woessner, D. D. Stevenson; Scripps Clinic, San Diego, CA.

333   Serum TGF-β1 in Allergic Asthma

W. Manuyakorn ¹, S. Benjaponpitak¹, W. Kamchaisatian¹, C. Setthaudom², K. Atamasirikul², C. Sasisakulporn³, C. Direkwattanachai¹; ¹Division of Allergy/Immunology, Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND, ²Department of Pathology, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND, ³Research Center, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND.

Poster Session

3202

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Asthma Pathogenesis

334   Systemic Autoimmunity Significance in Patients with Asthma

I. Agache ¹, L. Duca¹, M. Anghel²; ¹Transylvania University Brasov, Faculty of Medicine, Brasov, ROMANIA, ²Brasov County Hospital, Brasov, ROMANIA.

335   Allergy, Serum IgE, and Lung Function in Children and Adolescents With Severe or Difficult-to-Treat Asthma

T. Haselkorn ¹, S. J. Szefler², F. E. R. Simons³, D. R. Mink⁴, B. E. Chipps⁵, D. A. Wong¹, L. Borish⁶; ¹Genentech, Inc., South San Francisco, CA, ²Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO, ³Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, CANADA, ⁴Ovation Research Group, San Francisco, CA, ⁵Capital Allergy and Respiratory Disease Center, Sacramento, CA, ⁶University of Virginia Health Systems, Charlottesville, VA.

336   Asthma and Lung Dysfunction Among Disadvantaged Wheezing Infants Followed to Age 7 Years

M. D. Klinnert ^1,2, A. H. Liu^1,2, G. Herrera-Garcia¹, K. Walsh¹; ¹National Jewish Medical and Research Center, Denver, CO, ²University of Colorado Health Sciences Center, Denver, CO.

337   Short-term Growth Suppression assessed by Knemometry may predict Height Growth Suppression in Children with Asthma treated with Inhaled Glucocorticoids

O. D. Wolthers; Asthma and Allergy Clinic, Children's Clinic Randers, Randers, DENMARK.

338   IRF-1 Interferes with Steroid Function in Airway Smooth Muscle Cells

O. Tliba, H. Baidouri, Y. Amrani; University of Pennsylvania, Philadelphia, PA.

339   Predictive Factors for Air Trapping Measured by CT Scan in Asthma

A. A. Busacker ^1,2, C. Kotaru², T. Keefe¹, J. Newell², E. Hoffman³, S. E. Wenzel⁴; ¹Colorado State University, Fort Collins, CO, ²National Jewish Medical and Research Center, Denver, CO, ³University of Iowa, Iowa City, IA, ⁴University of Pittsburgh Medical Center, Pittsburgh, PA.

340   Exhaled Nitric Oxide Decreases during Acetylcholine-induced Bronchoconstriction in Children with Asthma

Y. Noma, M. Nagao, T. Fujisawa; Mie National Hospital, Tsu, JAPAN.

341   Forced Expiratory Maneuvers - Most Of Healthy Children Do Not Meet ATS Criteria For Spirometry

G. Siergiejko ¹, B. E. Nowowiejska², M. G. Kaczmarski², Z. Siergiejko²; ¹Children Hospital, Bialystok, POLAND, ²Medical University, Bialystok, POLAND.

342   Diurnal Assessment of Airways Inflammation in Patients with Asthma Utilizing eNO

J. D. Wolfe ¹, D. M. Dreon², B. R. Parikh², E. E. Hutchins², M. N. Bates³; ¹Asthma and Allergy Associates of Northern California, San Jose, CA, ²Aperon Biosystems Corp., Menlo Park, CA, ³University of California - Berkeley, Berkeley, CA.

343   Detection of Tissue Eosinophils and Evidence of Extensive Degranulation in Archived Clinical Biopsies Using a Novel Anti-Eosinophil Peroxidase Monoclonal Antibody

C. Protheroe, J. C. Lewis, T. N. Lunsford, G. DePetris, M. P. McGarry, N. A. Lee, J. J. Lee; Mayo Clinic Arizona, Scottsdale, AZ.

344   Adiposity May Enhance Pulmonary Dysfunction in Obese Asthmatics Adolescents

P. Rojas, P. Sakali, J. Estrada, R. Pasternak, C. Moore; louisiana state university, New Orleans, LA.

345   Gastroesophageal Reflux (GER) Cause Increase In Bronchial Reactivity

B. E. Nowowiejska ¹, G. Siergiejko², M. G. Kaczmarski¹, Z. Siergiejko¹; ¹Medical University, Bialystok, POLAND, ²Children Hospital, Bialystok, POLAND.

346   Effect of Smoking Cessation on AMP and Methacholine Airway Hyperresponsiveness in Cigarette Smokers

C. Russo, G. Piccillo, P. Caponnetto, A. Origlio, A. Bonaccorsi, A. Di Maria, R. Polosa; University Of Catania, Catania, ITALY.

347   Exhaled Breath Condensate (EBC) pH in the Evaluation of Asthma

C. A. Coop, L. L. Hagan, J. P. Dice; Wilford Hall Medical Center, San Antonio, TX.

348   Monitoring the Fractional Concentration of Exhaled Nitric Oxide (FE_NO) in Uncontrolled Asthma Before and After Steroid Therapy Using a New Portable Monitor

W. E. Berger; Allergy and Asthma Associates of Southern California, Mission Viejo, CA.

349   Is Spirometry a Better Tool Than Measurement of Peak Flow Rate for Monitoring a Rub-Test for Screening Exercise-Induced Asthma?

C. A. Charpin-Kadouch ¹, J. Ercoli¹, J. Quéralt¹, A. Palot², F. Pelleing³, D. Charpin²; ¹Maison de l'Allergie et de l'Environnement, Marseille, FRANCE, ²Assistance publique-Hôpitaux de Marseille, Marseille, FRANCE, ³Inspection d'Académie des Bouches-du-Rhône, Marseille, FRANCE.

350   Nitric Oxide Metabolites In Asthma And Copd

J. V. Garmendia ¹, D. Moreno, Jr.², N. E. Larocca¹, C. Tálamo³, J. B. De Sanctis¹; ¹Instituto de Inmunología. Universidad Central de Venezuela, Caracas, VENEZUELA, ²Cátedra de Fisiopatología del Instituto de Medicina Experimental y Servicio de Neumonología del Hospital Universitario de Caracas. Facultad de Medicina, Universidad Central de Venezuela., Caracas, VENEZUELA, ³IServicio de Neumonología. Hospital Universitario. Universidad Central de Venezuela, Caracas, VENEZUELA.

351   Performance Characteristics of a New Device for Assessment of Asthmatic Inflammation by Measurement of Exhaled Breath Temperature, the Dunev Thermometer, a Unique Tool for Asthma Management

T. A. Popov ¹, S. Dunev¹, T. Kralimarkova¹, S. Kraeva¹, L. M. DuBuske²; ¹Sofia Medical University, Sofia, BUL-GARIA, ²Immunology Research Institute of New England, Gardner, MA.

Poster Session

3203

Sunday, February 25, 2007

9:45 AM - 10:45 AM

B Cells and T Cells

352   Kainic Acid Treatment of B Cells Causes Increased CD23 Shedding

J. L. Sturgill; Virginia Commonwealth University, Richmond, VA.

353   Eosinophilic Fasciitis Associated with X-Linked Agammaglobulinemia: Report of Two Cases

P. Sriaroon ¹, N. Tangsinmankong¹, S. Skoda-Smith², M. E. Elder², J. W. Sleasman¹; ¹University of South Florida College of Medicine, St. Petersburg, FL, ²University of Florida College of Medicine, Gainesville, FL.

354   An Uncommon Familial Presentation of Long Standing Diarrhea and Common Variable Immunodeficiency Improved with IVIG Therapy

V. VELAZQUEZ, C. A. Camacho, C. A. Camacho; Hospital Episcopal San Lucas, Ponce, PR.

355   MR1, a Class Ib Molecule, Utilizes a MHC Class II Like Pathway to Activate Mucosal Associated Invariant T Cells

S. Huang ¹, A. Sant², T. Hansen¹; ¹Washington University in St. Louis, St. Louis, MO, ²University of Rochester, New York, NY.

356   Analysis of T Cell Skewing by a Receptor Targeted Allergen Variant Reveals Selective Enhancement of Th1-Promoting Cytokines at the APC Level

K. Hulse ¹, A. J. Reefer¹, S. M. Satinover¹, M. D. Chapman², V. Engelhard¹, J. A. Woodfolk¹; ¹University of Virginia, Charlottesville, VA, ²Indoor Biotechnologies Inc., Charlottesville, VA.

357   Synergy Between LPS and Immobilized anti-human CD3 mAb for Activation of Cord Blood CD3+ T cells

Y. Katz, M. Goldberg, N. Luknar-Gabor, G. Zadik-Mnuhin, P. Koch, J. Tovbin; Assaf-Harofeh Medical Center, Zerifin, ISRAEL.

358   Impaired Corticosteroid-induced Transactivation In Human CD8+ T Cells

L. Li, D. Y. M. Leung, E. Goleva; National Jewish Medical and Research Center, Denver, CO.

359   Circulating Foxp3⁺CD4⁺ regulates both Th1 and Th2 responses in vivo

K. Orihara ^1,2, M. Narita³, T. Tobe², A. Akasawa³, Y. Ohya³, K. Matsumoto¹, H. Saito¹; ¹National Research Institute for Child Health and Development, Tokyo, JAPAN, ²Showa University, Tokyo, JAPAN, ³National Center for Child Health and Development, Tokyo, JAPAN.

360   Delivery Of Augmented Il-2 Receptor Signals To Cd8+ T Cells Replaces The Requirement For Helper Function In The Generation Of Primary But Not Secondary Cd8+ T Cell Responses

L. E. Cheng ¹, P. D. Greenberg²; ¹University of California, San Francisco, San Francisco, CA, ²University of Washington, Seattle, WA.

361   Up-regulation of Granzyme B Gene Expression by Chemical Allergens

R. J. Dearman, H. T. Caddick, C. J. Betts, I. Kimber; Syngenta CTL, Macclesfield, UNITED KINGDOM.

362   The MAb CHO-131 Identifies a Subset of Cutaneous Lymphocyte-Associated Antigen T cells Enriched in P-Selectin Binding Cells

Z. Ni; University of Minnesota, St. Paul, MN.

363   IL-12/TGF-β1 Regulation of TCR Signal Transduction in Human Memory T Cells Associated with Malignant and Non-malignant Chronic Inflammatory Microenvironments

L. Broderick, R. B. Bankert; University at Buffalo, Buffalo, NY.

364   Activated CD4+ And CD4- Subsets Of T Lymphocytes Increase In Experimentally Induced Eosinophilic Esophagitis (EE)

M. Wang, E. B. Brandt, M. E. Rothenberg, A. Mishra; Division of Allergy and Immunology, Cincinnati Children Hospital Medical Center, Cincinnati, OH.

365   Effects of Stress Hormones on Regulatory T cell (Treg) and Intracellular TH1/TH2 Cytokine Levels in Normal Human PBMC

G. D. Marshall, D. D. Montgomery, S. R. Roy, J. B. Brock; University MS Medical Center, Jackson, MS.

366   Regulatory T Lymphocytes Distribution And Eosinophilic Gastroenteropathy

P. Vannelli, T. Yan, C. Barone, S. McGeady; Thomas Jefferson University, Philadelphia, PA and A.I. duPont Hospital for Children, Wilmington, DE.

367   Complete DiGeorge Syndrome Due to CHD7 Mutation

M. Sanka, N. Tangsinmankong, M. Loscalzo, J. W. Sleasman, M. J. Dorsey; University of South Florida College of Medicine, St. Petersburg, FL.

368   Factors Inducing Development of Childhood-onset Myasthenia Gravis by CD3 Spectratyping Analysis

H. Dokai, Y. Fujikawa, K. Nihei, N. Shinomiya; Toho University Medical Center, Tokyo, JAPAN.

369   Identification of Cytokine Heterogeneity within the Th2 Subset

N. Kim, B. A. Foster, C. Prussin; Laboratory of Allergic Diseases, NIAID/NIH, Bethesda, MD.

370   Variable Effects of Combination Corticosteroids and Catecholamines on Total β2-Adrenergic Receptors in Human CD4+ T-Lymphocytes

A. N. Salicru ¹, B. E. Crucian², M. A. Nelman-Gonzales², J. K. Actor¹, C. F. Sams³, G. D. Marshall, Jr.⁴; ¹Department of Pathology and Laboratory Medicine, The University of Texas Health Science Center, Houston, TX, ²NASA-Johnson Space Center Bioastronautics Team Inc, Houston, TX, ³NASA Human Adaptation and Countermeasures Office, Houston, TX, ⁴Division of Clinical Immunology and Allergy, The University of Mississippi Medical Center, Jackson, MS.

371   Idiopathic CD4 Lymphocytopenia With Cryptococcal Pneumonia: A Case Report In Literature In Review

R. W. Hostoffer, Jr. ¹, M. Eagam²; ¹Case Western Reserve University, Cleveland, OH, ²Lake Erie College of Osteopathic Medicine, Erie, PA.

372   Evaluation of NKT Cells in Leishmaniasis

R. A. Campos, J. M. Cunha, O. F. Jesus, O. Bacellar, F. C. C. Figueiredo, R. G. D. Lima, R. S. Matos, E. M. Carvalho; Universidade Federal da Bahia, Salvador-BA, BRAZIL.

373   B Cell Superantigen-induced Immune Complex Lung Inflammation

A. L. Anderson, A. I. Levinson; University of Pennsylvania, Philadelphia, PA.

Poster Session

3204

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Vaccines and Immunodiagnostics

374   Long-term Clinical Outcomes Following Vaccinia Associated Myopericarditis

M. R. Nelson ¹, L. C. Collins¹, J. E. Atwood¹, R. E. Eckert², E. A. Shry², D. J. Shelton¹, W. Scott¹, R. J. M. Engler¹; ¹Walter Reed Army Medical Center, Washington, DC, ²Brooke Army Medical Center, Fort Sam Houston, TX.

375   Does Early BCG (Tokyo Strain) Vaccination have Potency to Prevent Allergy in Infants?

R. Ito, H. Saito, K. Matsumoto; National Research Institute for Child Health & Development, Tokyo, JAPAN.

376   A Pilot Study: Trivalent Inactivated Influenza Vaccine (TIV) and Myopericarditis

M. I. Slingluff ¹, M. M. Klote¹, B. A. Hemann¹, M. R. Nelson¹, M. A. Yacavone¹, J. E. Atwood¹, S. Black², R. J. M. Engler¹; ¹Walter Reed Army Medical Center, Washington, DC, ²Kaiser Permanente Vaccine Study Center, Oakland, CA.

377   Headache After Trivalent Inactivated Influenza Vaccine (TIV): Gender Differences and Severity

S. Kim-Delio ¹, M. M. Klote¹, M. R. Nelson¹, W. W. Carr², R. D. Deguzman¹, C. P. Mikita¹, B. L. Martin¹, R. J. M. Engler¹; ¹Walter Reed Army Medical Center, Washington, DC, ²Walter Reed Army Medical Ctr-WRAIR, Washington, DC.

378   Adverse Reactions To Pneumovax Pneumococcal Vaccine-cases Of Hyperimmunization?

S. E. Mannan, E. Yousef; A. I. duPont Hospital for Children/Thomas Jefferson University Hospital, Wilmington, DE.

379   Knowledge, Attitudes and Beliefs (KAB) Regarding Reporting of Adverse Events Following Immunizations (AEFI)

P. A. Hutchinson ¹, M. R. Nelson¹, S. L. Hill¹, L. L. Duran², R. J. M. Engler¹; ¹Walter Reed Army Medical Center, Washington, DC, ²Walter Reed Army Medical Center-VHC, Washington, DC.

380   Primary Smallpox Vaccination Temporally Associated with New Onset Urticaria-Angioedema (UrtAng) Evolving to Chronic Disease

R. J. M. Engler, MD ¹, A. Marini², J. Green³, M. Klote¹, L. Collins⁴, P. V. Belandres⁴, S. T. Chang³, J. F. Williams⁵, M. R. Nelson¹; ¹Walter Reed Army Med Ctr.; Uniformed Services University of the Health Sciences, Washington, DC, ²Uniformed Services University of the Health Sciences, Bethesda, MD, ³Walter Reed Army Med Ctr, Washington, DC, ⁴Walter Reed Army Med Ctr., Washington, DC, ⁵Walter Reed Army Med Ctr-VHC, Washington, DC.

381   Thrombocytopenia and Measles-Mumps-Rubella (MMR) Vaccine: Managing Loss Of Immunity to MMR

L. C. Collins, Jr. ^1,2, M. C. Minor^1,2, N. C. Blacker^3,4, G. J. Robinson^3,4, R. J. M. Engler^1,2; ¹Walter Reed Army Medical Center, Washington, DC, ²Vaccine Healthcare Centers Network, Washington, DC, ³Womack Army Medical Center, Fayetteville, NC, ⁴Vaccine Healthcare Centers Network, Fayetteville, NC.

382   Pre-transplant Cellular Alloimmunity as Assessed by a Panel of Reactive T-Cells (PRT) and Risk of Post-transplant Allograft Rejection

M. R. Gupta ¹, M. Vieyra¹, D. E. Hricik², J. J. Augustine², L. Coleman¹, R. Starling¹, E. Poggio¹, P. S. Heeger¹; ¹Cleveland Clinic Foundation, Cleveland, OH, ²University Health Systems, Cleveland, OH.

383   Chimeric EGF Receptor That Detects IgE-binding/crosslinking

R. Nakamura; Natl Inst Health Sci, Tokyo, JAPAN.

384   Low Values of Allergen Specific IgE Antibodies are Clinically Useful and Give Predictive Information for Very Young Children

L. Soderstrom ¹, M. Nordlund², C. Nilsson², G. Lilja²¹Phadia AB, Uppsala, SWEDEN, ²Sachs' Children's Hospital, Sodersjukhuset, Stockholm, SWEDEN.

385   Development of a Clinical Flow Cytometry Assay to Measure in Vitro Lymphocyte Responses

E. C. Chenworth ¹, V. Nandakumar², R. S. Abraham²; ¹Division of Allergic Diseases, Mayo School of Graduate Medical Education, Rochester, MN, ²Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.

386   Component Resolved IgE, IgG and IgG4 Antibody Levels for Grass Pollen Allergic Patients in Specific Immunotherapy. A Pilot Study

J. Arnved¹, S. Ronborg¹, B. Kristensen², L. Soderstrom ³; ¹Lung and Allergy Clinic, Copenhagen, DENMARK, ²Sweden Diagnostics Denmark, Copenhagen, DENMARK, ³Phadia AB, Uppsala, SWEDEN.

387   Comparison of Skin Prick Tests and Allergen-specific IgE by MAST-CLA Technique in Allergic Thai Children

P. Vilaiphan, S. Numkiatwongsa, P. Chatchatee, J. Ngamphaiboon; King Chulalongkorn Memorial Hospital, Bangkok, THAILAND.

388   Allergen Recognizing Pattern in Patients Sensitized to Dermatophagoides pteronyssinus and Lepidoglyphus destructor

R. P. Reis ¹, A. P. Pires¹, T. Fonseca², R. Murta², A. F. Ferrão¹, L. A. Patrício¹, E. M. Tomaz¹, F. C. Inácio¹; ¹Hospital S. Bernardo, Setúbal, PORTUGAL, ²Amerlab DPC, Lisboa, PORTUGAL.

Poster Session

3205

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Indoor and Outdoor Allergens and Risk Factors for Sensitization

389   Airborne Spore Levels and Skin Test Reactivity in New Orleans following Hurricane Katrina

E. Levetin ¹, E. Horner², E. Davis³, S. B. Lehrer⁴; ¹University of Tulsa, Tulsa, OK, ²Air Quality Science, Marietta, GA, ³Ochsner Clinic Foundation, New Orleans, LA, ⁴Tulane University, New Orleans, LA.

390   Indoor Molds and Allergic Potential

M. D. W. Ward ¹, Y. Chung¹, L. B. Copeland¹, M. K. Selgrade¹, S. Vesper²; ¹US EPA, Research Triangle Park, NC, ²US EPA, Cincinnati, OH.

391   Seasonal Distribution of Airborne Alternaria Spores

J. D. K. McNairn; Children's Mercy Hospital, Kansas City, MO.

392   A Comparative Study of Airborne Grass Pollen and Grass Pollen Hypersensitivity in Tulsa and Sorrounding Areas in Northeast Oklahoma

R. S. Medagoda ¹, E. Levetin², J. Purser³, D. Stewart¹; ¹University of Ok, College of Medicine, Tulsa, OK, ²University of Tulsa, Tulsa, OK, ³Allergy Clinic of Tulsa, Tulsa, OK.

393   Respiratory Allergy and Airborne Pollen Concentrations in Italy from 1992 to 2004

E. Ridolo, R. Albertini, D. Giordano, L. Soliani, I. Usberti, P. Dall'Aglio; University of Parma, Parma, ITALY.

394   An Eight Year Survey (1998-2005) of the Major Tree Pollens in the Washington, DC Area

J. Yoon, M. R. Nelson, M. S. Marks, S. E. Kosisky; Walter Reed Army Medical Center, Washington, DC.

395   Typical Outdoor Levels of Airborne Fungal Spores Collected at Ground Level During Both The Rainy and Dry Seasons in Florida

R. Codina, L. S. Cohen, Jr., J. J. Mele; SDII Global Corporation, Tampa, FL.

396   The Air Spora Surrounding a Compost Facility in Northeast, Oklahoma

S. Gillum, E. Levetin; The University of Tulsa, Tulsa, OK.

397   Influence of Meteorological Conditions on Early Spring Pollen in the Tulsa Atmosphere from 1987-2006

E. Lo, E. Levetin; University of Tulsa, Tulsa, OK.

398   Predominant Weed and Grass Aeroallergens of the Washington, DC Area: an Eight Year Survey (1998-2005)

S. E. Kosisky, Sr.; Walter Reed Army Medical Center, Washington, DC.

399   Effect of Trimming Cypress Tree on Pollination

D. A. Charpin ¹, M. Calleja², C. Pichot³; ¹Assistance publique-Hôpitaux de Marseille, Marseille, FRANCE, ²Ecole Supérieure d'Agronomie de Montpellier, Montpellier, FRANCE, ³Institut National de la Recherche Agronomique, Avignon, FRANCE.

400   Characteristics of the Casuarina Pollen Season in the Sydney District, NSW

P. K. Burton, C. H. Katelaris; Institute of Immunology and Allergy Research, Westmead, AUSTRALIA.

401   September Asthma Spikes And Mold Aeroallergen Levels In A Southwestern Ontario Community: Correlation Or Coincidence?

J. Ohayon ¹, J. Anderson²; ¹McMaster University, Hamilton, ON, CANADA, ²London Health Sciences, London, ON, CANADA.

402   Seasonal Pollinosis Symptoms, Atmosphere Conditions And Pollens Count

C. Nunes, S. Ladeira; Center of Allergy of Algarve, Portimao, PORTUGAL.

403   “Farmhouse Mycosis”: Mold Assessment

J. J. Anderson ¹, P. J. Pityn²; ¹London Health Sciences Centre, London, ON, CANADA, ²Oshtech Inc., London, ON, CANADA.

404   Concordance Rates of Allergen Sensitization Amongst Family Members at an Inner City Asthma Center

F. Hajee, H. Solomon, M. Castro, C. Bowser, M. Rao, R. Joks; Center for Allergy and Asthma Research, SUNY Downstate Medical Center, Brooklyn, NY.

405   Risk Factors for Asthma in Adolescents: ISAAC Phase II in a Brazilian Coast City

L. M. Spinelli, N. A. Rosario, C. A. Riedi, A. V. Schmidt, J. J. Jorge, M. Malucelli, M. S. Cramer, J. C. Correa-Celi, A. Albanus; Federal University of Parana, Curitiba, BRAZIL.

406   Allergic Asthma and Rhinitis Caused by Household Rabbit Exposure: Identification of Seum-Specific IgE and Its Allergens

J. Choi ¹, H. Kim², H. Park²; ¹Bundang JeSaeng General Hospital, Seongnam-si, Kyunggido, REPUBLIC OF KOREA, ²Ajou University Hospital, Suwon-si, Kyunggido, REPUBLIC OF KOREA.

407   The Relationship Between Obesity, Menstrual Cycle, And Lung Function In Korean Adolescent Girls

H. J. Yang, Y. H. Jeon, B. Y. Pyun; Department of Pediatrics, College of Medicine, Soonchunhyang Univ Hospital, Seoul, REPUBLIC OF KOREA.

408   Development of a Murine Model for Assessment of Chronic Beryllium Disease

F. Salehi ¹, S. Audusseau¹, N. Karp¹, J. Zayed², B. Mazer¹; ¹McGill University, Montreal, PQ, CANADA, ²University of Montreal, Montreal, PQ, CANADA.

409   Tobacco Smoke Relation With Chronic Sinusitis And Nasal Polips

J. Martín-Lázaro ¹, D. D. Stevenson²; ¹Hospital Juan Canalejo, La Coruna, SPAIN, ²Scripps Clinic, La Jolla, CA.

Poster Session

3206

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Allergens: Molecular Biology, Structure and Function, and Cross Reactivity

410   Cockroach Allergen Bla g 2 Dimerizes in a Crystal Complex with an Antibody Fragment

A. Pomés ¹, M. Li², S. Wünschmann¹, M. D. Chapman¹, A. Wlodawer³, A. Gustchina³; ¹INDOOR Biotechnologies, Inc., Charlottesville, VA, ²Basic Research Program, SAIC-Frederick, Frederick, MD, ³Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, MD.

411   Purification And Characterization Of Allergens From Harmonia Axyridis (asian Lady Beetle): An Evolving Indoor Allergen

T. NAKAZAWA ¹, B. Dragulev¹, L. Goddard¹, J. Shannon¹, E. Peters², T. A. Platts-Mills¹; ¹University of Virginia, Charlottesville, VA, ²Asthma and Allergy Consultants, Austin, TX.

412   Mapping of Antigenic Determinants on Bla g 2 surface

S. Wünschmann ¹, M. Li², A. Gustchina³, A. Wlodawer³, M. Chapman¹, A. Pomés¹; ¹INDOOR Biotechnologies Inc., Charlottesville, VA, ²Basic Research Program, SAIC, Frederick, MD, ³Macromolecular Crystallography Laboratory, NCI, Frederick, MD.

413   IgE Recognition Pattern of Homologous Allergens Tested by Microarray-based Nanotechnology

E. Scala, A. Zaffiro, D. Quaratino, C. D'Ambrosio, M. Bernardi, P. Palazzo, M. Giani, A. Mari; Center for Clinical and Experimental Allergology, IDI-IRCCS, Rome, ITALY.

414   Stability of Major Allergen Proteins in Extract Mixes Diluted in Human Serum Albumin (HSA), Normal Saline (NSP), or Glycerin (GLY)

G. Plunkett; ALK-Abelló, Inc., Round Rock, TX.

415   Mapping Conformational Epitopes On Jun A 1, The Major Allergen Of Mountain Cedar Pollen

R. Tiwari, B. Ning, S. Negi, M. Endsley, D. Estes, C. Schein, W. Braun, T. Midoro-Horiuti, R. Goldblum; University of Texas Medical Branch, Galveston, TX.

416   Natural and Recombinant Amb a 1: Immunologic Analysis of IgE and Monoclonal Antibody Epitopes

N. Wopfner ^1,2, R. Bauer¹, J. Thalhamer^1,2, F. Ferreira^1,2, M. Chapman³; ¹University of Salzburg, Department of Molecular Biology, Salzburg, AUSTRIA, ²Christian Doppler Laboratory for Allergy Diagnosis and Therapy, Salzburg, AUSTRIA, ³Indoor Biotechnologies, Charlottesville, VA.

417   Proteomics Of The Major Pollen Allergen From Birch (Bet v 1), Hazel (Cor a 1), Oak (Que a 1), And Hornbeam (Car b 1)

A. M. Erler ^1,2, F. Ferreira^1,2, P. Briza¹; ¹University of Salzburg, Department of Molecular Biology, Salzburg, AUSTRIA, ²Christian Doppler Laboratory for Allergy Diagnosis and Therapy, Salzburg, AUSTRIA.

418   Molecular Cloning of Chortoglyphus arcuatus Allergens

E. Fernandez-Caldas ¹, L. Vailes², O. Troubina², E. King², L. Arlian³, M. Boquete⁴, V. Iraola¹, S. Lafosse-Marin⁵, M. Chapman²; ¹Laboratorios LETI S. L., Tres Cantos, SPAIN, ²Indoor Biotechnologies Inc., Charlottesville, VA, ³Wright State University, Dayton, OH, ⁴Hospital Xeral, Lugo, SPAIN, ⁵Cabinet d'Immuno-allergologie, Fort de France, MARTINIQUE.

419   Identification of an Allergen of Harmonia Axyridis (Multicolor Asian Lady Beetle)

J. E. Knuffman ^1,2, M. A. Opsahl¹, B. H. Gern¹, A. S. Pratt¹, H. Sanchez¹, R. K. Bush^1,2; ¹William S. Middleton Veterans Affairs Hospital, Madison, WI, ²University of Wisconsin Hospital and Clinics, Madison, WI.

420   N-terminus Amino Acid Analysis Of Four Independently Produced Recombinant Alt a1

H. Sanchez ¹, R. K. Bush^1,2; ¹William S. Middleton VA Hospital, Madison, WI, ²University of Wisconsin-Madison, Madison, WI.

421   Extraction and Purification of Art v 1, the Mugwort Pollen Major Allergen

M. Egger, P. Gruber, F. Ferreira; Department of Molecular Biology, Division of Allergy and Immunology, University of Salzburg, Salzburg, AUSTRIA.

422   Characterization of Ascaris lumbricoides Tropomyosin: Use of Recombinant Protein to Investigate IgE Antibody Responses

A. B. R. Santos¹, G. C. Arruda¹, A. S. Zampolo¹, M. C. Rodrigues¹, V. P. L. Ferriani¹, C. Oliver¹, M. S. Palma², V. S. Sales³, L. K. Arruda ¹; ¹School of Medicine of Ribeirão Preto-University of São Paulo, Ribeirão Preto, BRAZIL, ²Bioscience Institute, State University of São Paulo, Rio Claro, BRAZIL, ³Federal University of Rio Grande do Norte, Natal, BRAZIL.

423   The Cross-allergenecity of Pollens from Compositae Family: Dendranthema grandiflorum, Artemisia vulgaris and Taraxacum officinale

Y. W. Lee ¹, S. Y. Choi², E. K. Lee², J. H. Sohn², J. W. Park¹, C. S. Hong¹; ¹Dept of Int Med & Institute of Allergy, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA, ²Institute of Allergy, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA.

424   Biochemical Characterization Of Intact Allergen Extracts Vaccine (Alutard SQ®) And Chemically Modified Allergoid Vaccines Representing Birch, Grass And House Dust Mite

H. Henmar, K. Meno, L. Friberg, H. Ipsen; ALK-Abelló A/S, Hørsholm, DENMARK.

425   Senecio jacobea Pollen: A New Allergenic Source

O. Luengo ¹, R. Mollá², V. Pozo², V. Cardona¹, C. Geller-Bernstein³, Y. Waysel⁴, C. Lahoz², A. Cadahia¹; ¹Allergy Unit. Hospital Universitari Vall d'Hebron., Barcelona, SPAIN, ²Department of Immunology. Fundación Jiménez Díaz, Madrid, SPAIN, ³Kaplan Medical Center, Rehovot, ISRAEL, ⁴Tel Aviv University, Tel Aviv, ISRAEL.

426   Physicochemical and Immunochemical Characterization of Cyn d 24 from Bermuda Grass Pollen

S. Su ¹, l. chiu², s. yang¹, S. Huang³, L. Chou²; ¹Veterans General Hospital-Taipei, Taipei, TAIWAN, ²National Taiwan University, Taipei, TAIWAN, ³University of Florida, Gainesville, FL.

427   Epidemiological Evaluation of Allergenic Molecules IgE Reactivity Detected by means of a Proteomic Microarray Method

M. Giani, E. Guerra, M. Locanto, C. Mondino, L. Pirrotta, D. Pomponi, E. Scala, A. Mari; Center for Clinical and Experimental Allergology, IDI-IRCCS, Rome, ITALY.

428   Identification of the Russian Hamster Allergens (Phodopus sungorus)

J. A. Torres, M. de las Heras, C. Pastor, M. Fernandez-Nieto, S. Quirce, M. Madero, A. Enriquez-Matas, J. Sastre; Fundacion Jimenez Diaz, Madrid, SPAIN.

429   Assessment of the Potential Cross-Allergenicity between Hen's Egg Lysozyme and Recombinant Human Lysozyme

D. A. Moneret-Vautrin ¹, C. M. N. Astier², P. Franck¹, M. Morisset¹, F. Codreanu¹, O. Roitel³, S. L. Taylor⁴, D. R. Bethell⁵; ¹University Hospital, Nancy, FRANCE, ²INPL, Vandoeuvre-Les-Nancy, FRANCE, ³Laboratory of Molecular Medicine and Therapeutics, Vandoeuvre-Les-Nancy, FRANCE, ⁴University of Nebraska, Lincoln, NE, ⁵Ventria Bioscience, Sacramento, CA.

430   Specific IgE levels to Der p 1 and Der p 2 in patients sensitized to Dermatophagoides spp.

M. Boquete ¹, F. Carballada¹, C. Carballas¹, J. Carnés², V. Iraola², E. Fernández-Caldas², M. Chapman³; ¹Hospital Xeral de Calde, Lugo, SPAIN, ²Laboratorios LETI, SL, Tres Cantos, SPAIN, ³Indoor Biotechnologies Inc., Charlottesville, VA.

431   Production of Purified Native Alt a 1 at an Industrial Scale

M. Osterberg ¹, S. Jabbari¹, E. Hogbom², P. Brostedt²; ¹Allergon AB, Angelholm, SWEDEN, ²Phadia AB, Uppsala, SWEDEN.

Poster Session

3207

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Food Allergy I

432   Fig Allergy: Not Just Oral Allergy Syndrome (OAS)

N. V. Cruz, S. L. Bahna, A. K. Knight; Louisiana State University Health Sciences Center-Shreveport, Shreveport, LA.

433   A Case Series of Eosinophilic Esophagitis: Importance of Allergy Evaluation, Detection of Food Allergy and Avoidance Diet

V. Patel, S. Kearney; Lehigh Valley Hospital, Allentown, PA.

434   Prevalence of Sensitization to Food Allergens Among Food Allergy Index and Control Families

D. Caruso, F. Ouyang, J. A. Pongracic, R. Kumar, A. Schroeder, J. Costello, X. Wang; Children's Memorial Hospital, Chicago, IL.

435   Trends in Sensitisation to Aero and Food Allergens-Comparison between different Birth Cohorts

T. Dean ^1,2, C. Venter², R. Kurukuralaatchy², B. Pereira², S. Matthews², J. Grundy², C. B. Clayton², M. Fenn², B. Higgins¹, S. H. Arshad²; ¹University of Portsmouth, Portsmouth, UNITED KINGDOM, ²The David Hide Asthma and Allergy Research Centre, Isle of Wight, UNITED KINGDOM.

436   Racial Differences in Early Introduction of Solid foods, IgE and Incidence of Atopic Dermatitis and Wheeze

C. L. M. Joseph ¹, D. R. Ownby², S. L. Havstad¹, E. M. Zoratti³, C. C. Johnson¹; ¹Dept of Biostatistics and Research Epidemiology, Henry Ford Hospital & Health System, Detroit, MI, ²Medical College of Georgia, Augusta, GA, ³Section of Allergy & Clinical Immunology, Henry Ford Hospital & Health System, Detroit, MI.

437   Prevalence of Peanut and Shellfish Allergy in Singapore Children Estimated from a Questionnaire Survey

L. P. Shek ¹, J. Y. Soh², P. Z. Ng¹, E. A. Morales¹, S. Ma³, B. W. Lee¹; ¹National University of Singapore, Singapore, SINGAPORE, ²National University Hospital, Singapore, SINGAPORE, ³Ministry of Health, Singapore, SINGAPORE.

438   Food Allergen Sensitization is Independently Associated with Decreased Lung Function in Children

R. Kumar ¹, Y. Yu², J. A. Pongracic¹, A. Schroeder², B. Wang², X. Liu³, H. Xing³, X. Wang²; ¹Division of Allergy, Children's Memorial Hospital, Chicago, IL, ²The Mary Ann and J. Milburn Smith Child Health Research Program, Children's Memorial Hospital and Children's Memorial Research Center, Chicago, IL, ³Biomedical Institute, Anhui Medical University, Hefei, CHINA.

439   Demographic Information for Patients with Eosinophilic Esophagitis

M. L. Heltzer, J. P. Franciosi, M. Shuker, C. A. Liacouras, J. M. Spergel; Children's Hospital of Philadelphia, Philadelphia, PA.

440   Food Hypersensitivity (FHS) And Sensitisation To Food Allergens Over The First Three Years Of Life

C. Venter ¹, B. N. Pereira¹, J. Grundy¹, C. B. Clayton¹, B. Higgins², T. Dean^1,2; ¹The David Hide Asthma and Allergy Research Centre, Isle of Wight, UNITED KINGDOM, ²University of Portsmouth, Portsmouth, UNITED KINGDOM.

441   Cookies and Avoidance Diets - Impact of the Food Allergen Labeling and Consumer Protection Act (FALCPA) and Other Industry Practices on Ingredient Labeling of Cookies

S. L. Taylor ¹, G. A. Knudsen¹, S. L. Hefle¹, T. J. Furlong²; ¹Food Allergy Research and Resource Program (FARRP) at University of Nebraska, Lincoln, NE, ²Food Allergy & Anaphylaxis Network (FAAN), Fairfax, VA.

442   Transfer of Shrimp Allergens to Other Foods Through Cooking Oil?

S. B. Lehrer ¹, L. Kim¹, T. Rice¹, J. Saidu², J. Bell², R. Martin³; ¹Tulane University Health Sciences Center, New Orleans, LA, ²LSU Ag Center, Baton Rouge, LA, ³National Fisheries Institute, McLean, VA.

443   Familial Aggregation of Total and Food-Specific IgE

H. Tsai, R. Kumar, J. Pongracic, Y. Yu, J. Costello, M. O'Gorman, X. Wang; Children's Memorial Hospital and Children's Memorial Research Center, Chicago, IL.

444   ELISA and HPLC Comparison of Pediatric Amino Acid-based Nutritionals

G. O. Duska-McEwen; Abbott Laboratories, Columbus, OH.

445   Peanut Allergic Child Increases Risk for Peanut Allergy in Siblings

S. Huq ^1,2, J. Liem^1,2, A. Kozyrskyj^1,2, A. Becker^1,2; ¹University of Manitoba, Winnipeg, MB, CANADA, ²Manitoba Institute of Child Health, Winnipeg, MB, CANADA.

446   Study and Development of Food Allergy Herbal Formula (FAHF-2)

Y. Chen, K. Srivastava, H. Sampson, X. Li; Mt. Sinai School of Medicine, New York, NY.

447   Cross Reactivity in Mountain Cedar-Tomato Oral Allergy Syndrome

R. S. Bonds, R. Tiwari, B. Ning, E. W. Czerwinski, R. G. Goldblum, T. Midoro-Horiuti; University of Texas Medical Branch, Galveston, TX.

448   Investigation of the Safety to Allergic Patients of Biotechnologically Derived Enzymes used in the Food Industry

C. Bindslev-Jensen ¹, P. Skov², E. Roggen³, E. Friis³, T. Gehring³, P. Hvass³, D. Brinch³; ¹Odense University Hospital, Odense, DENMARK, ²RefLab, Copenhagen, DENMARK, ³Novozymes A/S, Bagsvaerd, DENMARK.

449   Food-Induced Anaphylaxis and Repeat Epinephrine Treatments

E. Oren, A. Banerji, S. Clark, C. A. Camargo, Jr.; Massachusetts General Hospital, Boston, MA.

450   Evaluation of Pediatric Patients Admitted with Adverse Food Reactions to an Inner-City Pediatric ED

S. Kiratiseavee, S. Ramesh; University of Buffalo, Buffalo, NY.

451   Roasted Peanuts Are More Likely to Sensitize Mice than Raw Peanuts

S. J. Maleki ¹, K. Yamaki²; ¹USDA-Agricultural Research Service, New Orleans, LA, ²National Food Research Institute, Tsukuba, JAPAN.

452   Children with Multiple Food Allergies are Not More Likely to be Underweight than Other Children

J. L. P. Protudjer, J. J. Liem, A. L. Kozyrskyj, A. B. Becker; University of Manitoba, Winnipeg, MB, CANADA.

453   The Natural History of Egg Allergy

J. H. Rabe, E. C. Matsui, K. E. Mudd, J. M. Skripak, R. A. Wood; Johns Hopkins Hospital, Baltimore, MD.

454   Identification of a MnSOD-like Protein as a New Major Pistachio Allergen

R. Ayuso, G. Grishina, K. Ahn, L. Bardina, K. Beyer, H. Sampson; Mt Sinai Medical Center, New York, NY.

455   Immunochemical and Biological Methods for Estimation of Allergen Content Used for Soy Allergy Risk Assessments of Biotechnologically Derived Products

M. H. Pedersen ¹, P. S. Skov¹, T. Holzhauser², C. Bindslev-Jensen³, D. S. Brinch⁴, L. K. Poulsen¹; ¹National university hospital of Denmark, Copenhagen, DENMARK, ²Paul-Ehrlich-Institut, Langen, GERMANY, ³Odense university hospital, Odense, DENMARK, ⁴Novozymes A/S, Bagsvœrd, DENMARK.

456   Basophil Activation In Food Allergic Patients

M. Worm; Dept. of Dermatology and Allergy, Berlin, GERMANY.

457   Association Between Milk Allergy, Steroid Use, And Rate Of Hospitalizations In Children With Asthma

A. B. Sympson^1,2, E. Yousef ^1,2; ¹DuPonts Children's Hospital, Wilmington, DE, ²Thomas Jefferson Uiniversity, Philadlephia, PA.

458   Epicutaneous Testing Using Peanut Extracts Prepared by a Variety of Cooking Methods

M. Peng ¹, G. Hubbard¹, J. A. Nordlee², S. L. Hefle², M. B. Levy¹; ¹Medical College of Wisconsin, Milwaukee, WI, ²University of Nebraska, Food Allergy Research and Resource Program, Lincoln, NE.

459   Sunflower Seed Food Allergy as a Co-allergy With Peanut

S. S. Comstock, C. Kath, S. S. Teuber; Univ CA-Davis School Medicine, Davis, CA.

460   Identification of a New Sesame Seed Allergen - Ses i 7, an 11 S Globulin belonging to the Seed Storage Proteins

K. Beyer ¹, G. Grishina², L. Bardina², H. A. Sampson²; ¹Charité, Berlin, GERMANY, ²Mount Sinai School of Medicine, New York, NY.

Poster Session

3208

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Food Allergy II

461   A Phase II, Randomized, Double-Blind, Parallel-group, Placebo-Controlled, Oral Food Challenge Trial of XOLAIR® (omalizumab) in Peanut Allergy (TOPS)

H. A. Sampson; Mount Sinai School of Medicine, New York, NY.

462   Relative Potency of Oral Antigens in Provoking Food Allergy in the Mouse

C. C. Bowman, M. K. Selgrade; USEPA, Research Triangle Park, NC.

463   Increased Prevalence of Vitamin D Deficiency Rickets Due to Inadequate Dietary Restrictions for the Treatment for Allergic Diseases

T. Muto ¹, S. Morii¹, R. Kimura¹, M. Futamura², K. Ito², T. Sakamoto¹; ¹Nagoya University Graduate School of Medicine, Nagoya, JAPAN, ²Aichi Children's Health and Medical Center, Obu, JAPAN.

464   Recognition of Clinical Tolerance to Baked Milk Products in Milk-Allergic Children

K. A. Bloom, A. Nowak-Wegrzyn, S. M. Walsh, E. D. Robinson, M. Mishoe, H. A. Sampson; The Mount Sinai Medical Center, New York, NY.

465   Novel Clinical Course Of IgE-mediated, Late-onset Anaphylaxis After Ingestion Bacillus Subtilis-Fermented Soybeans (natto): Clinical Review Of 7 Patients

N. Inomata, H. Osuna, K. Kawano, J. Yamaguchi, M. Yanagimachi, Z. Ikezawa; Yokohama City University Hosipital, Yokohama, JAPAN.

466   Cherry Allergy: How To Decrease The Allergenicity Of Cherry Industrial Derivatives

V. Pravettoni ¹, O. Brenna², L. Farioli³, L. Primavesi², S. Bonomi¹, S. Tonoli¹, C. Pompei², E. Pastorello³; ¹Operative Unit of Allergy and Clinical Immunology, Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena Foundation, IRCCS, Milan, Italy, ²Department of Food Science and Technology and Microbiotechnology, University of Milan, Milan, Italy, ³Operative Unit of Allergy and Clinical Immunology, Niguarda Ca' Granda Hospital, Milan, Italy.

467   Treatment of Natural Peanut Butter with Phytic Acid

S. CHUNG, E. T. Champagne; USDA-ARS, New Orleans, LA.

468   Multifaceted Food Allergy Education Program: Healthcare Provider Educational Resource Development

J. E. Yu ¹, S. Teuber², S. H. Sicherer¹; ¹Mt Sinai School Of Medicine, New York, NY, ²University of California, San Diego, San Diego, CA.

469   Assessment of Hypoallergenic Properties of the Santana Apple

H. S. Kootstra ¹, B. J. Vlieg-Boerstra¹, M. P. van der Maas², A. E. J. Dubois¹; ¹University Medical Center Groningen, Groningen, THE NETHERLANDS, ²Applied Plant Research, Wageningen UR, Wageningen, THE NETHERLANDS.

470   Can Egg-Allergic Children Recognize Egg Proteins In Breast Milk?

I. Cerecedo ¹, C. Alonzi², J. Wang³, L. Bardina³, A. Nowak-Wegrzyn³; ¹Hospital Ramon y Cajal, Madrid, SPAIN, ²Policlinico Gemelli, Università Cattolica del Sacro Cuore, Rome, ITALY, ³Mount Sinai School of Medicine, New York, NY.

471   Assessment of Oral Allergy to Apple with Rat Basophil Leukemia (RBL) Cells Transfected with Human Fcɛ Receptor and Passively Sensitized with Sera from Apple- and Birch-Allergic Individuals

R. Bencharitiwong, A. Nowak-Wegrzyn; Mount Sinai School of Medicine, New York, NY.

472   A New Murine Model of beta-Lactoglobulin-Specific IgE-Mediated Cow's Milk Hypersensitivity

K. Dairiki, N. Shimizu, T. Kaneko; Food Science Institute, Meiji Dairies Corporation, Odawara, Kanagawa, JAPAN.

473   Weaning to a Partially Hydrolyzed Whey Formula at Three Months of Age Protects Against the Later Development of Anti-Cow Milk IgE Antibodies in Comparison to Whole Cow's Milk or Extensively Hydrolyzed Whey Formulas

R. U. Sorensen ¹, J. Inostroza², E. Hebel², A. M. Vinet², J. Fierro², A. Roman², K. Mason¹; ¹LSU Health Sciences Center, New Orleans, LA, ²University of La Frontera, Temuco, CHILE.

474   Specific IgE Antibodies To ω-5 Gliadin - Indicator Of Wheat Anaphylaxis And Its Tolerance In Wheat Sensitized Children

R. Shibata ¹, S. Nishima¹, K. Kohno², E. Morita², H. Matsuo³, A. Tanaka⁴; ¹Fukuoka National Hospital, Fukuoka, JAPAN, ²Department of Dermatology, Shimane University School of Medicine, Shimane, JAPAN, ³Graduate School of Biomedical Scineces, Hiroshima University, Hiroshima, JAPAN, ⁴Phadia KK, Tokyo, JAPAN.

475   Food Allergy Symptoms As A Consequence Of Subconscious Stress Responses

K. Nekam ¹, K. Toth², L. M. DuBuske³; ¹Hospital of the Hospitaller Brothers of St. John of God, Budapest, HUNGARY, ²Institute of Psychology, University of Pécs, Pecs, HUNGARY, ³Immunology Research Institute of New England, Gardner, MA.

476   Cashew Allergy Demographics, Presentation and Cross Reactivity in a US Cohort

A. W. Grigg ¹, I. C. Hanson^1,2, C. M. Davis^1,2; ¹Baylor College of Medicine, Houston, TX, ²Section of Allergy and Immunology, Department of Pediatrics,Texas Children's Hospital, Houston, TX.

477   Identification of Pistachio (Pistacia vera) Allergens of 11s Globulin and 2s Albumin Family

K. Ahn; Samsung Medical Center, Sunkyunkwan University School of Medicine, Seoul, REPUBLIC OF KOREA.

478   Accidental Allergic Reactions (AAR) In Children With Cow's Milk Allergy (CMA)

M. Boyano; Hospital Infantil La Paz, Madrid, SPAIN.

479   Associations of Prick Skin Tests and Allergen Specific IgE in Children and Adults

J. A. Pongracic ¹, F. Ouyang², J. S. Kim¹, D. Caruso², H. Wang², X. Wang²; ¹Division of Allergy, Children's Memorial Hospital, Chicago, IL, ²The Mary Ann and J. Milburn Smith Child Health Research Program, Children's Memorial Hospital and Children's Memorial Research Center, Chicago, IL.

480   Utility of the Direct Basophil Activation Test in Predicting Tolerance to Dietary Milk Protein in Children With a History of Cow's Milk Allergy

N. Wanich, A. Nowak-Wegrzyn, S. Walsh, B. Robinson, S. Noone, H. A. Sampson, W. G. Shreffler; Mount Sinai School of Medicine, New York, NY.

481   Establishing Objective Detection Limits for the Pepsin Digestion Assay Used in the Assessment of Genetically Modified Foods

A. O. Ofori-Anti, L. Chen, H. L. Lee, R. E. Goodman; University of Nebraska, Lincoln, Lincoln, NE.

482   Bird-egg Syndrom In A 80 Years Old Patient

A. Losada ¹, M. Dieguez¹, E. González¹, B. de Valdés¹, J. Carnes², M. Díez¹; ¹Servicio de Alergia Hospital Ramon y Cajal, Madrid, SPAIN, ²Laboratorios LETI I+D, Madrid, SPAIN.

483   Egg-bird Syndrome In A Five Year Old Patient

B. de Valdés ¹, E. Gonzalez¹, M. Diéguez¹, J. Carnés², B. De la Hoz¹, S. Terrados¹; ¹Allergy Department. Hospital Ramon y Cajal, Madrid, SPAIN, ²I+D Laboratorios LETI, Madrid, SPAIN.

484   IgE Mediated Food Allergy in Childhood: Novel Concepts in Allergic Immune Response

S. Donnanno ¹, M. Rosado², G. Trimarco³, F. Capolunghi², S. Cascioli², M. C. Artesani¹, R. Carsetti², G. Cavagni¹; ¹C.O.U. of Allergy, Pediatric Medicine Department, IRCCS, Osp. Pediatrico Bambino Gesù, Rome, Roma, ITALY, ²Research Laboratory of Flow Cytometry and B cells Development, IRCCS, Osp. Pediatrico Bambino Gesù, Rome, Roma, ITALY, ³O.U. of Allergy, Pediatric Department, University of Parma, Roma, ITALY.

485   Analysis of Peanut Allergenic Components for Chinese Patients

H. Li; Peking Union Medical College Hospital, Beijing, CHINA.

486   Allergic Proctocolitis Associated With Cow's Milk With An Unusual Evolution

C. M. A. Jacob, D. L. A. Pitarello, A. C. Pastorino, M. M. F. Trevisan, Y. L. Koda, E. Vidolin, A. P. B. M. Castro; Depto. of Pediatrics, São Paulo, BRAZIL.

487   Presence, Loss, and Recurrence of Walnut Allergy after Chemotherapy

W. L. Ebbeling; William L. Ebbeing, MD, INC, APMC, Fresno, CA.

488   Egg's allergy: an experience from Brazilian Food Allergy Reference Center

C. M. A. Jacob, A. C. Pastorino, D. Munhoz, R. G. Ramos, T. Batelochio, A. C. Brandão, A. K. F. Gushken, G. H. Yonamine, A. P. B. M. Castro; Faculty of Medicine of University of Sao Paulo, Sao Paulo, BRAZIL.

Poster Session

3209

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Epidemiology and Informatics

489   The Effect of Increasing Study Enrollment on Willingness to Adopt Newly Validated Asthma Therapies

P. Khoury, J. O'Brien, S. K. Aberegg; The Ohio State University, Columbus, OH.

490   Adherence To Immunotherapy Protocols, SLIT Vs. SCIT

R. Garcia-Ibanez, D. M. Pollina; The AllergiGroup, Tampa, FL.

491   Low Temperature is a Strong Risk Factor for the Onset of Atopic Dermatitis in Children in Japan

K. Matsumoto, H. Saito; National Research Institute for Child Health and Development, Tokyo, JAPAN.

492   Prevalence of Self-reported Adverse Drug Reaction/Drug Allergy in a Singaporean Paediatric Population

T. Tan ¹, H. Van Bever²; ¹National University of Singapore, Singapore, SINGAPORE, ²Department of Paediatrics, National University of Singapore, Singapore, SINGAPORE.

493   Locating Evidence-based Literature in Immunology Using PubMed/MEDLINE

K. E. Deeney, A. F. Carr; NN/LM Pacific Southwest Region, UCLA, Los Angeles, CA.

494   Childhood Obesity as a Possible Aggravating Factor of Atopic Dermatitis

T. Kusunoki ^1,2, T. Morimoto³, R. Nishikomori², T. Heike², M. Ito¹, S. Hosoi⁴, T. Nakahata²; ¹Shiga Medical Center for Children, Moriyama, Shiga, JAPAN, ²Department of Pediatrics, Graduate School of Medicine, Kyoto University, Kyoto, JAPAN, ³Medical Education Center, Kyoto University, Kyoto, JAPAN, ⁴Ako City Hospital, Ako, Hyogo, JAPAN.

495   Prevalence of Atopy in Rural China among Children and Adults

J. S. Kim ¹, F. Ouyang², J. A. Pongracic¹, B. Wang², X. Liu³, H. Xing³, D. Caruso², X. Wang²; ¹Division of Allergy, Children's Memorial Hospital, Chicago, IL, ²The Mary Ann and J. Milburn Smith Child Health Research Program, Children's Memorial Hospital and Children's Memorial Research Center, Chicago, IL, ³Biomedical Institute, Anhui Medical University, Hefei, CHINA.

496   Risk Factors of Atopy in the First Two Years of Life in Indonesian Children

B. Setiabudiawan, C. B. Kartasasmita; Hasan Sadikin General Hospital, Bandung, INDONESIA.

497   Does Breastfeeding (BF) Prevent Allergic Sensitization? Results of Probit II

B. D. Mazer ^1,2, L. Matush³, R. Platt¹, I. Vanilovich³, M. Kramer¹; ¹McGill University/Montreal Children's Hosp., Montreal, PQ, CANADA, ²Meakins Christie Laboratories, Montreal, PQ, CANADA, ³National Research and Applied Medicine Mother and Child Centre, Minsk, BELARUS.

498   Association of Parental Gender and Allergic Sensitization with the Patterns of Sensitization in 18 year-old Offspring in the Detroit Area Childhood Allergy Study

R. T. Misiak ¹, G. Wegienka¹, S. Havstad¹, D. R. Ownby², C. C. Johnson¹, E. M. Zoratti¹; ¹Henry Ford Health System, Detroit, MI, ²Medical College of Georgia, Augusta, GA.

Poster Session

3210

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Allergic Inflammation I

499   Plasmacytoid Dendritic Cells from Asthmatic Patients Exhibit Increased FcERI Expression

M. A. Gill, T. A. George, V. Gan, K. Long, I. Dougherty, R. Gruchalla; UT Southwestern Medical Center at Dallas, Dallas, TX.

500   The Anti-Inflammatory Effect of Ciglitazone is Partially Mediated by Glucocorticoid Induced Leucine Zipper in Human Airway Epithelial Cells

A. L. Wagelie-Steffen ¹, J. Eddleston^1,2, J. Herschbach^1,2, B. L. Zuraw^1,2; ¹University of Califonia, San Diego, San Diego, CA, ²Veterans Medical Research Foundation, La Jolla, CA.

501   Mice Deficient in Atrial Natriuretic Peptide Receptor A (NPRA) Exhibit Decreased Lung Inflammation: Implication of NPRA Signaling in Asthma Pathogenesis

X. Kong ^1,2, X. Wang¹, G. Hellermann¹, R. F. Lockey¹, S. Mohapatra¹; ¹University of South Florida, Tampa, FL, ²James A. Haley Veterans Hospital, Tampa, FL.

502   [Withdrawn]

503   The Effect of Daily Apolipoprotein A-I Mimetic Therapy on T15-Type Autoantibodies Against Oxidized Phosphatidylcholine in a Murine Model of Asthma

K. S. Konduri ¹, S. D. Nandedkar¹, D. Weilrauch¹, D. A. Rickaby¹, N. Duzgunes², K. A. Pritchard¹; ¹Medical College of Wisconsin and Zablocki VA Medical Center, Milwaukee, WI, ²University of Pacific School of Dentistry, San Franscisco, CA.

504   LILRB4 Suppresses the Development of Th2 Allergic Airway Inflammation

J. J. Rao, N. A. Barrett, F. I. Hsu, Y. Kanaoka, K. F. Austen, H. R. Katz; Brigham and Women's Hospital, Brookline, MA.

505   Inhibiting Pollen Nadph Oxidase-induced Signal By Intrapulmonary Administration Of Antioxidants Blocks Allergic Airway Inflammation

N. G. Dharajiya ¹, B. K. Choudhury¹, A. Bacsi², I. Boldogh¹, R. Alama³, S. Sur¹; ¹University of Texas Medical Branch, Galveston, TX, ²Institute of Immunology, University of Debrecen, Debrecen, HUNGARY, ³National Jewish Medical & Research Center, Denver, CO.

506   IL-4 Bypasses Innate Immune Signals in Inhalational Priming

A. Dittrich, K. Bottomly; Yale University School of Medicine, New Haven, CT.

507   A Murine Model Of Childhood Asthma

H. Mayuzumi ¹, Y. Ohki², K. Tokuyama³, T. Mizuno², H. Arakawa², H. Mochizuki², A. Morikawa²; ¹Gunma Children's Medical Center, Shibukawa, JAPAN, ²Gunma University Graduate School of Medicine, Maebashi, JAPAN, ³Takasaki University of Health and Welfare, Takasaki, JAPAN.

508   Nerve Growth Factor Induces Goblet Cell Hyperplasia And Muc5ac Production In A Human Epithelial Cell Line

A. Micera ^1,2, B. Stampachiacchiere¹, A. Lambiase², S. Bonini², S. Bonini^3,4; ¹IRCCS-G.B. Bietti Eye Foundation, Rome, ITALY, ²Dept. of Ophthalmology, University Campus Bio-Medico, Rome, ITALY, ³Internal Medicine, Second University of Naples, Naples, ITALY, ⁴CNR, Institute of Neurobiology and Molecular Medicine, Rome, ITALY.

509   Role of Insulin-like Growth Factor (IGF)-I in Human and Experimental Asthma

H. Yoshihara ¹, T. Adachi¹, H. Nagase¹, N. Yamashita², K. Ohta¹; ¹Teikyo University School Medicine, Tokyo, JAPAN, ²Musashino University, Tokyo, JAPAN.

510   Effect of Inflammatory Cytokines on the Expression of Tie-2 Receptors in Structural Cells of the Lung

T. O. Makinde ¹, D. K. Agrawal²; ¹Creighton University, Department of Biomedical Sciences, Omaha, NE, ²Creighton University, Departments of Biomedical Sciences, Internal Medicine, Medical Microbiology and Immunology., Omaha, NE.

511   Role of Protein Tyrosine Phosphatase SHP-1 in Oxidative Stress and Development of Allergic Airway Inflammation

Y. Cho, S. Oh, Z. Zhu; Johns Hopkins Asthma and Allergy Center, Baltimore, MD.

512   Comparison of Central and Peripheral Airway Inflammation between Cough Variant Asthma and Mild Asthma by Examination of Hypertonic Saline Inhalation-Induced Sputum

T. Shimoda ¹, Y. Obase², R. Kishikawa¹, S. Shoji¹, S. Nishima¹; ¹Fukuoka National Hospital, Fukuoka, JAPAN, ²Kawasaki Medical School, Kurashiki, JAPAN.

513   Role of Inducible Nitric Oxide Synthase Pathway in the Development of Non-eosinophilic Asthma

H. Park ¹, S. Sohn¹, C. Park¹, H. Kwon¹, D. Kim¹, S. Kim¹, Y. Chang², S. Lee³, D. Choi⁴, S. Cho¹, S. Chang⁵, K. Min¹, Y. Kim¹; ¹Seoul National University Hospital, Seoul, REPUBLIC OF KOREA, ²Seoul National University Bundang Hospital, Seongnam, REPUBLIC OF KOREA, ³Cheongju St. Mary's Hospital, Cheongju, REPUBLIC OF KOREA, ⁴Samsung Medical Center, Seoul, REPUBLIC OF KOREA, ⁵Sungae General Hospital, Gwangmyung, REPUBLIC OF KOREA.

514   Increase of Amphiregulin Level in Sputum during Exacerbation of Acute Asthma Attacks in Children

Y. Enomoto ^1,2, T. Takamasu², M. Nakazawa³, K. Kurihara², M. Minami³, H. Saito¹, Y. Okayama¹; ¹RIKEN Yokohama Institute, Yokohama, JAPAN, ²Kanagawa Children's Medical Center, Yokohama, JAPAN, ³Yokohama City University Graduate School of Medicine, Yokohama, JAPAN.

515   siRNA Targeting the Natriuretic Peptide Receptor-A Prevents Airway Inflammation in a Mouse Model of Allergic Asthma

X. Wang ^1,2, W. Xu¹, X. Kong¹, S. Shirley¹, R. Lockey^1,2, S. Mohapatra^1,2; ¹University of South Florida, Tampa, FL, ²James A. Haley Veterans Hospital, Tampa, FL.

516   Volume-regulated Chloride Channel-3 in PDGF-Induced Proliferation of Human Bronchial Smooth Muscle Cells

A. Ramanathan Arumugham ¹, D. K. Agrawal^1,2; ¹Dept of Biomedical Sciences, Creighton University School of Medicine, Omaha, NE, ²Dept of Internal Medicine, Creighton University School of Medicine, Omaha, NE.

517   Microsomal Prostaglandin E Synthase-1 Deficiency Increases Dust Mite Antigen-Induced Airway Inflammation

S. N. Nallamshetty ¹, S. Uematsu², S. Akira², J. A. Boyce¹; 11Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA, ²Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, JAPAN.

518   Role of Glycogen Synthase Kinase 3 in regulating Vascular Permeability associated with Asthma

Y. Morimoto, N. Goplen, R. Alam; National Jewish Medical and Research Center, Denver, CO.

519   Towards Systems Biology In Allergy Research

R. Renkonen; Biomedicum & Haartman Institute, University of Helsinki, Helsinki, FINLAND.

520   Effect Of Tnf-α (-308g/a) Polymorphism And Combined Effect With Il-13 Polymorphisms In Bronchial Responsiveness Of Korean Children With Asthma

H. Kim ¹, M. Kang², S. Lee³, J. Kim¹, B. Kim¹, S. Jang², M. Sohn⁴, K. Kim⁴, S. Hong¹; ¹Asan Medical Center, Seoul, REPUBLIC OF KOREA, ²Asan Institute for Life Science, Seoul, REPUBLIC OF KOREA, ³Hallym Medical Center, Seoul, REPUBLIC OF KOREA, ⁴Yonsei University, Seoul, REPUBLIC OF KOREA.

521   Internalization of CysLT1 Receptor Through the Clathrin Endocytic Pathway

K. Audette, J. Larrivee, C. Thompson, M. Rola-Pleszczynski, J. Stankova; Universite de Sherbrooke, Sherbrooke, PQ, CANADA.

522   Clearance of Mycoplasma Pneumoniae Is Impaired in Mice with Established Allergic Airway Inflammation

D. D. Chaplin, C. L. Zindl, L. B. Duffy, T. P. Atkinson, J. Lai; University of Alabama at Birmingham, Birmingham, AL.

523   Ascaris Antigens Suppress Experimental Allergic Inflammation

S. Trivedi ¹, M. G. Hodges¹, V. Bundoc¹, H. H. Norris², A. Boesen¹, S. Madala¹, J. F. Urban³, A. Keane-Myers¹; ¹LAD/NIAID/NIH, Rockville, MD, ²NIAID/NIH, Rockville, MD, ³NRFL, USDA, Beltsville, MD.

524   Hookworm Protein Necator Americanus - Ancyclostoma Secreted Protein 2 (na-asp-2) Inhibits Allergic Airway Inflammation

J. G. Patel ¹, P. J. Hotez², N. G. Dharajiya¹, S. Sur¹; ¹University of Texas Medical Branch, Galveston, TX, ²George Washington University, Washington, DC.

Poster Session

3211

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Cytokines I

525   Tumour Necrosis Factor Alpha (TNFα) Peptide-based Vaccines Suppress Murine Airway Allergic Responses

A. G. Ma, Y. Ma, T. Zhang, A. B. Becker, Z. Peng; University of Manitoba, Winnipeg, MB, CANADA.

526   Role of the RNA-binding Protein HuR in Posttranscriptional Regulation of IL-13 in T Cells

C. Stellato ¹, X. Fang¹, B. Tancowny¹, J. Fan¹, F. Wu¹, S. Y. Asaki¹, U. De Fanis¹, S. Huang¹, M. Gorospe², U. Atasoy³, V. Casolaro¹; ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²National Institute of Aging, NIH, Baltimore, MD, ³University of Missouri-Columbia, Columbia, MO.

527   A New Immunotherapy Approach: Mucosal Immunization With An Il-13 Vaccine Suppresses Murine Airway Allergic Responses

Y. Ma, A. G. Ma, S. Basu, Y. Zhou, A. J. Halayko, K. T. HayGlass, A. B. Becker, F. E. R. Simons; University of Mnitoba, Winnipeg, MB, CANADA.

528   Role of the RNA-binding Protein Tristetraprolin (TTP) in Glucocorticoid (GC)-mediated Gene Regulation

F. T. Ishmael ¹, X. Fang¹, N. Heller¹, J. Fan¹, P. J. Blackshear², U. Atasoy³, C. Cheadle¹, C. Stellato¹; ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²National Institute of Environmental Health Sciences, Research Triangle Park, NC, ³University of Missouri-Columbia, Columbia, MO.

529   Comparison of Expression and Cellular Provenance of Thymic Stromal Iymphopoietin and Chemokines in Patients with Severe Asthma, COPD and Controls

Q. Meng ¹, B. O'Connor¹, J. Ratoff¹, D. Cousins¹, G. Z. Zhang², S. Y. Gu², J. S. Zhao², T. H. Lee¹, C. J. Corrigan¹, S. Ying¹; ¹King's College London, London, UNITED KINGDOM, ²Third Clinical College, Jilin University, Jilin, CHINA.

530   The Role Of Il-25 In Airway Allergic Response

P. Angkasekwinai ¹, H. Park², Y. Wang¹, Y. Wang¹, Y. Liu¹, Z. Zhu³, C. Dong¹; ¹MD Anderson Cancer Center, Universtiy of Texas Health Science Center, Houston, TX, ²University of Washington, Seattle, WA, ³Johns Hopkins University School of Medicine, Baltimore, MD.

531   Humanized Anti-IL-5 Therapy (Mepolizumab) Reduces Eosinophil Responsiveness to the Eotaxins

M. L. Stein, B. K. Buckmeier, M. E. Rothenberg; Cincinnati Childrens Hospital Medical Center, Cincinnati, OH.

532   Effect Of Breast Milk Feeding From Allergic And Non-allergic Mothers On Infant During The First 4-years Of Life

W. Kim ¹, H. Yoon²; ¹Inje University, Seoul, REPUBLIC OF KOREA, ²Hallym University, Seoul, REPUBLIC OF KOREA.

533   Synergistic Effect of Double-Stranded RNA and TGF-α on MUC5AC production in Human Bronchial Epithelial Cells

H. Tadaki, H. Arakawa, T. Mizuno, T. Suzuki, H. Mochizuki, K. Tokuyama, A. Morikawa; Gunma University, maebashi, JAPAN.

534   Nitric Oxide (NO) Inhibits Human Rhinovirus (HRV)-16-Induced Transcription of IP-10 (CXCL10) in Human Airway Epithelial Cells (HAE)

R. Koetzler, D. Proud; University of Calgary, Calgary, AB, CANADA.

535   Role of Th2-molecules in OVA-Induced Intestinal Anaphylaxis

E. E. Forbes ^1,2, K. R. Groschwitz¹, R. Ahrens¹, E. B. Brandt¹, M. E. Rothenberg¹, P. S. Foster^2,3, K. I. Matthaei², S. P. Hogan¹; ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²John Curtin School of Medical Research, Australian National University, Canberra, AUSTRALIA, ³Asthma, Allergy and Inflammation Research Center, University of Newcastle, Newcastle, AUSTRALIA.

536   Sputum Epithelial Cell-Derived Neutrophil-Activating Peptide-78 (ENA-78/CXCL5) in Asthmatic Children

N. M. Heshmat ¹, G. A. Mostafa¹, M. M. Abd Al-Aziz², E. M. Abd El-Bary¹; ¹Pediatrics Department, Ain Shams University, Cairo, EGYPT, ²Clinical Pathology Department, Ain Shams University, Cairo, EGYPT.

537   Small-interfering RNA Decreases IL-13 Receptor α1 (IL-13Rα1) Expression and Signalling in Human Tonsillar B Cells

O. Hajoui, J. Guay, A. Banville-Langelier, B. Mazer; Meakins Christie Laboratories, Montreal, PQ, CANADA.

538   Effect of IL-13 and IL-13 Mutant (IL-13E13K) on Airway Hyperresponsiveness (AHR) and Airway Smooth Muscle (ASM) In Mice

P. R. Gendapodi ¹, M. Kioi², R. K. Puri², P. Abel¹, R. G. Townley¹; ¹Creighton University, Omaha, NE, ²NIH, Bethesda, MD.

539   Protein Microarray Analysis in Patients with Asthma: Elevation of the Chemokine PARC/CCL18 in Sputum

C. Kim ^1,2, H. Kim¹, T. Kurian¹, T. Kobayashi², K. Hirohito²; ¹Inje University, Seoul, REPUBLIC OF KOREA, ²Mayo Clinic, Rochester, MN.

540   Level Of Cytokine In Children Of Acute Mycoplasma Pneumoniae Infection And Wheeze

H. Yoon ¹, W. Kim²; ¹Hallym University, Seoul, REPUBLIC OF KOREA, ²Inje University, Seoul, REPUBLIC OF KOREA.

541   Aspartate Protease From Alternaria Induced Cytokine Production, And Calcium Signaling In Human Airway Epithelial Cells Through A Protease-activated Receptor-2 (par-2)

Y. Matsuwaki ^1,2, T. White¹, K. Hotta¹, Y. Inoue¹, C. B. Lawrence³, H. Kita¹; ¹Mayo Clinic, Rochester, MN, ²Jikei university, school of medicine, Tokyo, JAPAN, ³Virginia Biotech Institute, Blacksburg, VA.

542   CXCR2 Chemokines Regulate Tube Formation of Human Lung Microvascular Endothelial Cells

A. Matsuda, H. Saito, K. Matsumoto; National Research Institute for Child Health and Development, Tokyo, JAPAN.

543   Oxidative Stress Regulates IL-4 Gene Expression In Mast Cells Through Reduction Of Histone Deacetylase (HDAC)

Y. Nakamaru ¹, D. Takagi¹, M. Maeda¹, P. J. Barnes², S. Fukuda¹, K. Ito²; ¹Hokkaido univ. graduate school of med., Sapporo, JAPAN, ²NHLI, Imperial College, London, UNITED KINGDOM.

544   Targeted Disruption of Smad3 Affects the IL-13 Expression of Lung in a Mouse Model of Asthma

M. Anthoni ¹, G. Wang^1,2, M. Leino¹, A. Lauerma¹, H. Alenius¹, H. Wolff^1,3; ¹Finnish Institution of Occupational Health, Helsinki, FINLAND, ²Department of Dermatology and Venereology, Qingdao University Medical College Hospital, Qingdao, CHINA, ³Department of Pathology, Helsinki University Central Hospital, Helsinki, FINLAND.

545   Immunomodulating Properties of Stored Product Mite Extracts on Human Dermal Fibroblasts

L. G. Arlian, M. S. Morgan, K. T. Peterson, D. Vyszenski-Moher; Wright State University, Dayton, OH.

546   Inhibition Of Airway Inflammation And HIV Entry By NNY-CCL14 Treatment: Role Of CCR1 And CCR5

S. Gupta ¹, B. Fuchs², S. Schulz-Maronde¹, A. Heitland¹, S. E. Escher¹, J. Münch³, F. Kirchhoff³, M. Mack⁴, H. C. Tillmann⁵, A. Braun², W. G. Forssmann¹, U. Forssmann⁶, J. Elsner⁷; ¹Hannover Medical School, Hannover, GERMANY, ²Fraunhofer Institute of Toxicology & Experimental Medicine, Hannover, GERMANY, ³University of Ulm, Ulm, GERMANY, ⁴University of Regensburg, Regensburg, GERMANY, ⁵VIRO Pharmaceuticals GmbH & Co. KG, Hannover, GERMANY, ⁶IPF PharmaCeuticals GmbH, Affiliated Institute of Hannover Medical School, Hannover, GERMANY, ⁷Fachklinik Bad Bentheim, Bad Bentheim, GERMANY.

547   IP-10 Moderates Rhinovirus Induced IFN-α Production and Stimulates IL-10

S. Kakumanu, W. W. Busse, J. E. Gern; University of Wisconsin Hospital and Clinics, Madison, WI.

548   Effects Of Intranasal TNFα On Granulocyte Recruitment In Healthy Individuals And Patients With Allergic Rhinitis

H. D. Widegren ¹, M. Korsgren¹, J. Erjefalt², M. Andersson¹, L. Greiff¹; ¹Lund University Hospital, Lund, SWEDEN, ²Lund University, Lund, SWEDEN.

549   Plasma Concentration of CCR4 Ligands in Asthma Patients During Bronchial Challenge with Dermatophagoides Pteronyssinus (Dp) Allergen

K. Kowal ¹, S. Zukowski¹, L. DuBuske², A. Bodzenta-Lukaszyk¹; ¹University Medical School of Bialystok, Bialystok, POLAND, ²Immunology Research Institute of New England, Gardner, MA.

550   Determination of mRNA Expression and Serum Levels for IL-4 and IL-13 in Asmathic Patients

R. Farid, J. Tavakol Afshari, M. Boskabadi; Mashad University Medical Sciences, Mashad, IRAN (ISLAMIC REPUBLIC OF).

Poster Session

3212

Sunday, February 25, 2007

9:45 AM - 10:45 AM

Rhinosinusitis, Mechanisms and Treatment

551   Prevalence of Nonallergic Triggers among Seasonal Allergic Rhinitics and Normals

D. Shusterman ¹, M. Murphy²; ¹University of Washington, Seattle, WA, ²University of California, San Francisco, CA.

552   Role Of Prostaglandin D2 And E2 Terminal Synthases In Chronic Rhinosinusitis

M. Okano ¹, T. Fujiwara¹, M. Yamamoto¹, H. Hattori¹, K. Nishizaki¹, Y. Sugata¹, Y. Urade²; ¹Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, JAPAN, ²Osaka Bioscience Institute, Osaka, JAPAN.

553   Cytokines and Chemokines in NARES and Nasal Polyposis

C. Klemens ¹, F. Jund¹, A. Klemens², C. Devens¹, M. F. Kramer¹; ¹Oto-Rhino-Laryngology, Head and Neck Surgery, Ludwig-Maximilians-University Munich, Munich, GERMANY, ²Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Zentralklinikum Augsburg, Augsburg, GERMANY.

554   Population-Based Association Study Of TLR Gene Polymorphisms In Chronic Rhinosinusitis

M. A. Tewfik ¹, Y. Bossé², T. J. Hudson², M. Desrosiers¹; ¹McGill University, Montreal, PQ, CANADA, ²McGill University and Genome Quebec Innovation Centre, Montreal, PQ, CANADA.

555   The Role Of Fungi In Sinus Polyposis

A. M. Hofman, T. Hofman, W. Skrobisz; Center of Allergology, Poznan, POLAND.

556   Remodelling in Nasal Polyposis is Independent of TH-Cell Polarisation

N. Zhang, T. v. Zele, P. Gevaert, G. Holtappels, P. v. Cauwenberge, C. Bachert; Universitair Ziekenhuis Gent, Ghent, BELGIUM.

557   Correlations between Rhinitis associated Impairment of Quality of Life and Levels of ECP and Tryptase

F. Jund ¹, C. Klemens¹, R. Jund², C. Devens¹, M. F. Kramer¹; ¹Oto-Rhino-Laryngology, Head and Neck Surgery, Ludwig-Maximilians-University Munich, Munich, GERMANY, ²ENT Clinic, Puchheim, GERMANY.

558   The Correlation between Allergen Skin Prick Test (SPT) Wheal Diameters and Nasal Symptoms to Aeroallergen Challenge in Environmental Exposure Chamber (EEC)

D. Wilson, A. Salapatek, P. Tanna, P. Patel; Allied Research International, Mississauga, ON, CANADA.

559   Investigation Of Olfactory Threshold Responses In Chronic Rhinitis Subtypes

M. Rezvani ¹, L. Hastings², D. Brandt¹, J. Bernstein¹; ¹University of Cincinnati, Cincinnati, OH, ²Osmic Enterprises, Cincinnati, OH.

560   A Pilot, Prospective, Double Blind, Placebo-Controlled Treatment Trial with Itraconazole Orally in Patients with Chronic Rhinosinusitis and Asthma

E. Frigas; Mayo Clinic, Rochester, MN.

561   Intranasal Corticosteroids That Provide Sustained Efficacy May Improve Patient Satisfaction and Adherence to Therapy

E. Meltzer ¹, J. Boyle², J. Droar³; ¹Allergy and Asthma Medical Group and Research Center, San Diego, CA, ²Schulman, Ronca and Bucuvalas, Inc., New York, NY, ³Altana Pharma US, Florham Park, NJ.

562   Coadministration of Intranasal Ciclesonide and Inhaled Fluticasone Propionate-Salmeterol in Perennial Allergic Rhinitis (PAR)

K. Kim ¹, J. Quesada¹, M. A. Wingertzahn², N. Szmaydy-Rikken², P. Darken², T. Shah²; ¹West Coast Clinical Trials, LLC, Long Beach, CA, ²Altana Pharma US, Florham Park, NJ.

563   The Pharmacokinetics (PK), Safety and Tolerability of Fexofenadine HCl 6mg/mL Suspension in Children with Allergic Rhinitis (AR): a Multicenter, Open-label, Single-dose Study

R. E. Grubbe ¹, A. S. Nayak², B. Kittner³, N. Segall⁴; ¹Center Of Research Excellence, L.L.C., Oxford, AL, ²Sneeze, Wheeze & Itch Associates, LLC, Normal, IL, ³sanofi-aventis U.S. Inc., Bridgewater, NJ, ⁴Clinical Research Atlanta, Atlanta, GA.

564   The 30mg Dose of Fexofenadine HCl 6mg/mL Suspension is Bioequivalent to the Marketed 30mg Tablet in Healthy Adult Subjects under Fasted Conditions: a Randomized, Crossover, Open-label Study

D. N. Morrison ¹, S. Sahasranaman²; ¹Bio-Kinetic Clinical Applications, Inc., Springfield, IL, ²sanofi-aventis U.S. Inc., Bridgewater, NJ.

565   How Effective Are New Generation Antihistamines In Combination With Nasal Steroids In Patients Suffering From Severe Allergic Rhinitis And Concomitant Asthma?

R. Mosges, J. Koberlein; University of Cologne, Cologne, GERMANY.

566   Long-term Efficacy of Ciclesonide in Adult and Adolescent Patients With Perennial Allergic Rhinitis

P. Chervinsky ¹, S. Kunjibettu², D. Miller¹, B. Prenner³, G. Raphael⁴, T. Shah⁵; ¹Northeast Medical Research Associates, North Dartmouth, ME, ²Altana Pharma US, Florham Park, NJ, ³Allergy Associates Medical Group, Inc., San Diego, CA, ⁴Bethesda, MD, Bethesda, MD, ⁵Altana Pharma, Florham Park, NJ.

567   Onset of Action of Azelastine Nasal Spray Compared to Mometasone Nasal Spray and Placebo in Patients with Seasonal Allergic Rhinitis (SAR)

P. Patel ¹, D. Wilson¹, C. D'Andrea², H. Sacks²; ¹Allied Research International, Mississauga, ON, CANADA, ²MedPointe Pharmaceuticals, Somerset, NJ.

568   A Case of Chronic Rhinosinusitis

S. Sattar, A. Casillas; UCLA Medical Center, Los Angeles, CA.

569   Evidence for Elevated IL-6 and its Signaling Components in Chronic Rhinosinusitis with Nasal Polyps

A. T. Peters, B. Tancowny, L. Suh, M. Agashe, K. Harris, D. Conley, R. Kern, L. Grammer, R. Schleimer; Northwestern University Medical School, Chicago, IL.

570   Nasal and Airway Inflammatory Features of Subjects with Nasal Polyposis With or Without Asthma

M. Boulay; Centre de recherche, Hôpital Laval, Quebec, PQ, CANADA.

Oral Abstract Session

3601

Sunday, February 25, 2007

2:00 PM - 3:15 PM

The Role of Infection in Asthma

571   Absence of Relationship between History of Tuberculosis Infection, Skin Tuberculin Responses and Development of Adult Bronchial Asthma, Allergic Rhinitis and Atopy

J. Li, S. Y. Li, Z. M. Zhou, D. F. Luo, J. Y. An, B. Q. Sun, N. S. Zhong; Guangzhou Institute of Respiratory Disease, Guangzhou, CHINA.

572   Viral Etiology and Rhinovirus Serotypes of Recurrent Respiratory Illnesses during Infancy

T. Jartti ¹, T. Pappas¹, W. Lee¹, R. F. Lemanske, Jr.², J. E. Gern¹; ¹Department of Pediatrics, University of Wisconsin, Madison, WI, ²Department of Medicine, University of Wisconsin, Madison, WI.

573   Respiratory Syncytial Virus-Induced Gene Expression Profiles in Human Respiratory Epithelial Cells: Effect of pretreatment with Th1/Th2-type cytokines

Y. Yamada ¹, S. Yoshihara¹, K. Matsumoto², M. Saikusa³, N. Hashimoto², T. Homma², O. Arisaka¹, H. Saito²; ¹Dokkyo University School of Medicine, Mibu, Tochigi, Japan, ²National Research Institute for Child Health and Development, Department of Allergy and Immunology, Tokyo, Japan, ³Yokohama Health Research Institute, Kanagawa, Japan.

574   Coronavirus NL63 Illnesses in Infancy are a Risk Factor for Asthma at Age Six

T. E. Pappas ¹, K. T. Sullivan Dille¹, W. Lee¹, K. A. Grindle¹, K. A. Roberg¹, D. F. Da Silva¹, C. J. Tisler¹, E. L. Anderson¹, K. M. Hansen¹, R. A. Grabher¹, L. E. Pleiss Salazar¹, M. D. Evans², R. Gagnon², J. E. Gern¹, R. F. Lemanske, Jr.¹; ¹University of Wisconsin School of Medicine and Public Health, Madison, WI, ²University of Wisconsin Population Health Sciences Biostatistics and Medical Informatics, Madison, WI.

575   Seasonal Distribution Of Respiratory Viruses In Pediatric Asthma In Trinidad West Indies

J. Matthew ¹, L. M. PintoPereira¹, T. E. Pappas², C. Swenson², K. Grindle², K. Roberg², R. F. Lemaske, Jr.², W. Lee², J. E. Gern²; ¹The University of the West Indies, St Augustine, TRINIDAD AND TOBAGO, ²University of Wisconsin-Madison, Madison, WI.

576   Analysis of Airway Immune System Responses to Rhinovirus Infection in Children and Resultant Tendency to Wheeze

B. K. Smith ¹, C. J. Tisler², T. E. Pappas², D. Mueller², D. F. DaSilva³, J. E. Gern⁴, R. F. Lemanske, Jr.⁴; ¹University of Wisconsin School of Medicine and Public Health, Madison, WI, ²University of Wisconsin Hospital, Madison, WI, ³University of Wisconsin Hospital, Madison, WI, ⁴University of Wisconsin, Madison, WI.

Oral Abstract Session

3602

Sunday, February 25, 2007

2:00 PM - 3:15 PM

Genetic Regulation of Immune Function

577   Myosin Light Chain Kinase (MYLK) Variants that Confer Increased Risk of Sepsis and Acute Lung Injury are Associated with Asthma and Associated Phenotypes

L. Gao ¹, A. Grant¹, P. Chi¹, P. Gao¹, M. Stockton¹, H. Watson², N. N. Hansel³, G. Diette³, G. Dunston⁴, R. A. Mathias⁵, A. Togias¹, R. Brower³, J. Sevransky³, J. P. Maloney⁶, M. Moss⁶, C. Shanholtz⁷, J. G. N. Garcia⁸, T. H. Beaty⁹, K. C. Barnes¹; ¹Johns Hopkins Asthma and Allergy Ctr., Baltimore, MD, ²University of the West Indies, West Indies, BARBADOS, ³Division of Pulmonary and Critical Care Medicine, The Johns Hopkins University, Baltimore, MD, ⁴National Human Genome Center at Howard University, Washington, DC, DC, ⁵National Human Genome Research Institute, Baltimore, MD, ⁶Division of Pulmonary and Critical Medicine, University of Colorado Health Sciences Center, Denver, CO, ⁷University of Maryland School of Medicine, Baltimore, MD, ⁸Department of Medicine, The University of Chicago Biological Sciences, Chicago, IL, ⁹Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD.

578   Comprehensive Analysis of Mannan-Binding Lectin (MBL) Status in a Cohort of Healthy Donors as Determined by MBL Protein Concentration, MBL Complement Pathway Function and MBL and MASP-2 Genotypes

J. Yu, D. Sheets, J. F. Halsey, J. D. Hester; IBT Reference Laboratory, Lenexa, KS.

579   Clara Cell secretory 10-Kd Protein Sequence Variation Is Associated with the Severity of Asthma and Glucocorticoid Responsiveness

L. Chen ^1,2, J. Huang², M. Kuo³, K. Yeh², S. Huang⁴; ¹Chang Gung Children's Hospital, Taiwan, LA, ²Division of Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Children's Hospital, and Chang Gung University, Taoyuan, TAIWAN, ³Chang Gung University, Taoyuan, TAIWAN, ⁴Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD.

580   Ethnicity Plays a Role in Differential Human Toll-like Receptor Responsiveness

K. T. HayGlass, Y. Lissitsyn, A. Kozyrskyj, A. B. Becker; Univ Manitoba, Winnipeg, MB, CANADA.

581   Single Nucleotide Polymorphism in IL-9 Promoter Influences Promoter Strength

P. Huyett, S. Early, E. Barekzi, L. Borish, J. W. Steinke; Asthma and Allergic Diseases Center, Charlottesville, VA.

582   A Polymorphism In Human CD40 Correlates With Autoimmunity And Enhances B Cell Activation

A. L. Peters ¹, P. M. Gaffney², G. A. Bishop^1,3; ¹University of Iowa, Iowa City, IA, ²University of Minnesota, Minneapolis, MN, ³VA Medical Center, Iowa City, IA.

Oral Abstract Session

3603

Sunday, February 25, 2007

2:00 PM - 3:15 PM

Anaphylaxis and Venoms

583   Anaphylactic Mechanisms in Sudden Unexpected Infant Death: Elevated Concentrations of Mast Cell Carboxypeptidase in the Serum

X. Zhou ¹, M. G. Buckley¹, J. Lucas¹, S. Variend², A. F. Walls¹; ¹Southampton General Hospital, Southampton, UNITED KINGDOM, ²Children's Hospital, Sheffield, UNITED KINGDOM.

584   HLA Class I and Class II Associations with Bee and Wasp Venom Allergy

B. A. Sin ^1,2, H. Tutkak³, G. Pasaoglu⁴, K. Köse⁵, Z. Misirligil⁶; ¹Ankara University School of Medicine, Ankara, TURKEY, ²Ankara University School of Medicine Department of Allergic Diseases, Ankara, TURKEY, ³Ankara University School of Medicine, Dept.of Rheumatology and Immunology, Ankara, TURKEY, ⁴Ankara University School of Medicine, Dept. of Allergic Diseases, Ankara, TURKEY, ⁵Ankara University School of Medicine, Dept. of Biostatistics, Ankara, TURKEY, ⁶Ankara University School of Medicine, Dept.of Allergic Diseases, Ankara, TURKEY.

585   Seafood Allergy & Risk of Adverse Reactions to Radiocontrast Media: Are Physicians Unwittingly Propagating A Medical Myth?

A. D. Beaty ¹, P. L. Lieberman², R. G. Slavin¹; ¹Division of Allergy & Immunology, Saint Louis University School of Medicine, St. Louis, MO, ²University of Tennessee Center for the Health Sciences, Memphis, TN.

586   Immunologic Characteristics Correlate With Reactions to Sting Challenge

D. B. K. Golden ¹, J. S. Schroeder¹, R. G. Hamilton¹, L. B. Schwartz², T. J. Craig³, A. Kagey-Sobotka¹; ¹Johns Hopkins University, Baltimore, MD, ²Virginia Commonwealth University, Richmond, VA, ³Penn State Hershey Medical Center, Hershey, PA.

587   A 1-Day Rush Immunotherapy Schedule for Imported Fire Ant Hypersensitivity

J. J. Dietrich, L. M. Moore, S. Nguyen, L. L. Hagan, M. S. Tankersley; Department of Allergy and Immunology, Wilford Hall Medical Center, Lackland Air Force Base, San Antonio, TX.

588   Parental Use of EpiPen for Inner-City Children with Food Allergy

J. A. Sinacore ¹, J. S. Kim², A. S. Murthy², J. A. Pongracic²; ¹Department of Preventive Medicine and Epidemiology, Loyola University Stritch School of Medicine, Maywood, IL, ²Division of Allergy, Children's Memorial Hospital, Chicago, IL.

Oral Abstract Session

3604

Sunday, February 25, 2007

2:00 PM - 3:15 PM

Outcomes and Quality of Life

589   Parental Anxiety Before And After Food Challenges In Children With Suspected Peanut And Hazelnut Allergy

W. T. Zijlstra; UMC Utrecht, Utrecht, THE NETHERLANDS.

590   Addition of Omalizumab Reduces School Absenteeism in Children with Moderate-Severe Persistent Asthma

H. Milgrom ¹, M. Massanari², R. J. Maykut², F. Kianifard², R. K. Zeldin², G. P. Geba²; ¹National Jewish Medical and Research Center, Denver, CO, ²Novartis Pharmaceuticals Corporation, East Hanover, NJ.

591   Numerical Skills and Asthma Outcomes

A. J. Apter, J. Cheng, D. Small, I. M. Bennett, C. Albert, D. G. Fein, M. George, S. Van Horne; University of Pennsylvania, Philadelphia, PA.

592   Reliability and Validity of the Paediatric Food Allergy Questionnaire (PFAQ;Parent Form): A New Scientific Measure of HRQoL

A. DunnGalvin ¹, A. DuBois², B. De Blok², H. Oude-Elberink², J. O. B. Hourihane¹; ¹University College Cork, Cork, IRELAND, ²Groningen Universiteit, Groningen, THE NETHERLANDS.

593   Assessment of the Psychometric Properties of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ) in Moderate to Severe Pediatric Asthma Patients

F. S. Lobo ¹, D. Revicki², W. Grant³, F. Turk⁴, M. Massanari¹; ¹Novartis Pharmaceuticals, East Hanover, NJ, ²UnitedBioSource, Bethesda, MD, ³James Madison University, Harrisonburg, VA, ⁴Novartis Pharmaceuticals, Basel, SWITZERLAND.

594   Tracking Quality of Life Changes in Asthma Requires Disease-Specific Measure for Optimal Sensitivity

K. M. Shanovich, K. T. Sullivan Dillie, M. D. Evans, K. A. Roberg, E. L. Anderson, K. M. Hanson, R. A. Grabher, D. F. DaSilva, T. E. Pappas, L. E. P. Salazar, C. J. Tisler, R. E. Gangnon, J. E. Gern, R. F. Lemanske; University of Wisconsin, School of Medicine and Public Health, Madison, WI.

Oral Abstract Session

3605

Sunday, February 25, 2007

2:00 PM - 3:15 PM

Eosinophils as Effectors and Regulators of Allergy

595   Co-Expression of IL-5 and Eotaxin-2 in Mice Creates a Novel and Eosinophil-dependent Pulmonary Model of Respiratory Inflammation Characteristic of Human Disease

S. I. Ochkur ¹, T. Biechele¹, E. Jacobsen¹, B. McElhinney², C. Protheroe¹, R. S. Pero¹, M. T. Borchers³, K. R. O'Neill¹, D. C. Colbert¹, M. P. McGarry¹, Y. Janssen-Heininger², C. Irvin², H. H. Shen⁴, J. J. Lee¹, N. A. Lee¹; ¹Mayo Clinic Arizona, Scottsdale, AZ, ²Vermont Asthma Center, Burlington, VT, ³University of Cincinnati College of Medicine, Cincinnati, OH, ⁴Second Hospital, Zhejiang University, Hangzhou, PR, CHINA.

596   A Causative Link Exists Between Eosinophil Major Basic Protein-2 and Allergen-Induced Airway Hyperresponsiveness

K. O'Neill ¹, C. Protheroe¹, S. I. Ochkur¹, E. Jacobsen¹, D. C. Colbert¹, L. Rinaldi², C. Irvin², M. P. McGarry¹, J. J. Lee¹, N. A. Lee¹; ¹Mayo Clinic Arizona, Scottsdale, AZ, ²Vermont Asthma Center, Burlington, VT.

597   Inducible Expression of the IL-13 Transgene in the Lung Results in IL-13 Accumulation, Eosinophilia, and Tissue Remodeling in the Esophagus

L. Zuo, P. C. Fulkerson, C. Blanchard, M. E. Rothenberg; Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

598   Extra-vasation of Leukocytes from Circulation is Controlled by Gαi2 Signaling Events in the Endothelium

R. S. Pero ¹, M. T. Borchers², K. Spicher³, S. I. Ochkur¹, L. Sikora⁴, S. P. Rao⁵, K. R. O'Neill¹, H. Abdala-Valencia⁶, H. Shen⁷, M. I. Simon⁸, M. P. McGarry¹, N. A. Lee¹, J. M. Cook-Mills⁶, P. Sriramarao⁹, L. Birnbaumer¹⁰, J. J. Lee¹; ¹Mayo Clinic Arizona, Scottsdale, AZ, ²University of Cincinnati College of Medicine, Cincinnati, OH, ³Heinrich Heine University, Dusseldorf, GERMANY, ⁴La Jolla Institute for Molecular medicine, San Diego, CA, ⁵La Jolla Institute for Molecular Medicine, San Diego, CA, ⁶Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Zhejiang University College of Medicine, Hangzhou, CHINA, ⁸California Institute of Technology, Pasadena, CT, ⁹La Jolla Institute of Melecular Medicine, San Diego, CA, ¹⁰National Institute of Environmental Health Sciences, Triangle Park, NC.

599   T-Cell Death-Associated Gene 8 Critically Regulates Airway Eosinophilia in Allergen-Challenged Mice

A. R. Collier ¹, C. G. Radu², O. N. Witte³, M. E. Rothenberg¹, N. Zimmermann¹; ¹Cincinnati Children's Hospital, Cincinnati, OH, ²University of California - Los Angeles, Los Angeles, CA, ³University of California - Los Angeles and Howard Hughes Medical Institute, Los Angeles, CA.

600   Eosinophils are Required for T Cell Infiltration of Lungs During Allergic Asthma Responses

E. Walsh, N. Sahu, A. August; The Pennsylvania State University, University Park, PA.

Oral Abstract Session

3606

Sunday, February 25, 2007

2:00 PM - 3:15 PM

Rhinitis and Ocular Disorders

601   Anticholinergic Effects of Antihistamine Drugs Used in the Clinic

S. C. Wolff, K. Brubaker, T. Navratil, E. H. Fulcher, J. R. Lankford, J. L. Boyer; Inspire Pharmaceuticals, Durham, NC.

602   Vernal Keratoconjunctivitis (vkc) Treated With 0.1% Fk-506 Ophthalmic Ointment: Result Of A Three Years Follow-up

P. Pacharn, N. Visitsunthorn, O. Jirapongsananuruk, P. Vichyanond; Siriraj Hospital, Bangkok, THAILAND.

603   Shedding of the Soluble Receptor for TNFα, TNFR1, is Inhibited by the TACE Inhibitor TAPI2 in Conjunctival Epithelial Cells

E. B. Cook, J. L. Stahl, N. P. Barney, F. M. Graziano; University of Wisconsin-Madison, Madison, WI.

604   Ocular Allergy: A National Epidemiologic Study

K. Singh, L. Bielory; UMDNJ, Newark, NJ.

605   Symptoms of Allergic Rhinitis in Mothers during Early Pregnancy are Associated with Higher Prevalence of Allergic Rhinitis in their Offspring

M. Shinohara ^1,2, H. Wakiguchi¹, H. Saito², K. Matsumoto²; ¹Kochi University, Kochi Medical School, Department of Pediatrics, Kochi, JAPAN, ²National Research Institute for Child Health and Development, Tokyo, JAPAN.

606   Allergic Rhinitis and Inner-City Children — Is There a Relationship to Sleep-Disordered Breathing?

N. Gupta ¹, U. Emre¹, S. Kearney², R. A. Fermo¹, B. Silverman¹, A. T. Schneider¹; ¹Long Island College Hospital, Brooklyn, NY, ²Lehigh Valley Hospital, Allentown, PA.

Featured Poster Session

3801

Sunday, February 25, 2007

5:30 PM - 6:30 PM

Genetics and Pharmacology of Asthma Response

607   Haplotype Tagging SNPs in the Beta Adrenergic Receptor (ADRB2) Gene are Associated with Pre and Post-bronchodilator Lung Function in Preschool Children

A. Simpson, J. Hankinson, S. Borg-Bartolo, L. Lowe, S. John, A. Woodcock, W. Ollier, A. Custovic; University of Manchester, Manchester, UNITED KINGDOM.

608   Effect of Anti-IgE Antibody Omalizumab on Airway Remodeling and the Expression of Interleukins in Asthma

O. Korzh, S. Krasnokutskiy, E. Lavrova; Kharkov Medical Academy of Postgraduate Education, Kharkov, UKRAINE.

609   Exhaled Nitric Oxide Levels are Associated with Daily Lung Function Declines and Increased Medication Usage in Urban Children with Moderate to Severe Asthma Despite Use of Inhaled Corticosteroids and Long-acting Bronchodilators

N. Rabinovitch ¹, L. Zhang², E. W. Gelfand¹; ¹Department of Pediatrics, NJMRC, Denver, CO, ²Division of Biostatistics, NJMRC, Denver, CO.

610   Airway Remodeling and Lack of Bronchodilator Response in Steroid Resistant (SR) Asthma

E. Goleva, P. J. Hauk, J. Boguniewicz, R. J. Martin, D. Y. M. Leung; National Jewish Medical and Research Ctr., Denver, CO.

Featured Poster Session

3802

Sunday, February 25, 2007

5:30 PM - 6:30 PM

Innate Mechanisms Regulating Allergy and Host

611   IL-4 and IL-13 Induction of SOCS-3 Negatively Regulates TNF-α and IFN-γ Induced Human β Defensin (HBD)-3 Expression in Keratinocytes

H. R. Fairchild, D. Y. M. Leung, M. D. Howell; National Jewish Medical and Research Center, Denver, CO.

612   Tumour Necrosis Factor Alpha (TNFα) Vaccines in the Downregulation of Bowel Inflammatory Responses in Mice

Y. Zhou, A. G. Ma, Y. Ma, G. Qing, T. Zhang, Z. Peng; University of Manitoba, Winnipeg, MB, CANADA.

613   A Novel Card-Card Interaction is revealed by the Crystal Structure of Nod1-Card

N. P. Coussens; University of Iowa, Iowa City, IA.

614   Txk, A Nonreceptor Tyrosine Kinase of The Tec Family, Selectively Downregulates TRIF-Dependent Activation Program in LPS-Stimulated Mast Cells

T. Ohno ¹, J. Kashiwakura^1,2, H. Saito^3,1, Y. Okayama¹; ¹RIKEN Yokohama Institute, Yokohama, JAPAN, ²La Jolla Institute for Allergy and Immunology, San Diego, CA, ³National Research Institute for Child Health and Development, Tokyo, JAPAN.

615   Regulatory Role for Gr-1⁺ Cells and CD11b⁺ Cells in Lungs of Mice

J. Lai, C. L. Zindl, Y. Jung, L. Duffy, T. P. Atkinson, D. D. Chaplin; University of Alabama at Birmingham, Birmingham, AL.

Featured Poster Session

3803

Sunday, February 25, 2007

5:30 PM - 6:30 PM

The Best of EORD

616   High Environmental Tobacco Smoke Exposure and Presence of IL4 Polymorphism (C-589T) Increases Risk of Infant Wheezing: the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS)

A. M. Smith ¹, D. I. Bernstein¹, G. K. LeMasters², N. L. Huey³, G. K. Khurana Hershey³; ¹University of Cincinnati, Department of Internal Medicine, Cincinnati, OH, ²University of Cincinnati, Department of Environmental Health, Cincinnati, OH, ³Cincinnati Children's Hospital Center for Translational Research in Allergy and Asthma, Cincinnati, OH.

617   BASE a Major Cat Allergen

S. E. O'Neil, W. Smith, T. K. Heinrich, B. J. Hales, W. R. Thomas; Telethon Institute for Child Health Research, West Perth, AUSTRALIA.

618   Cockroach Allergen Reduction by Extermination Alone in Low-Income, Urban Homes-A Randomized Control Trial

M. L. Sever ¹, S. J. Arbes, Jr.¹, D. C. Zeldin¹, C. Schal², R. G. Santangelo², J. C. Gore², B. Vaughn³, H. Mitchell³; ¹NIEHS, Research Triangle Park, NC, ²NCSU, Raleigh, NC, ³Rho, Inc., Chapel Hill, NC.

619   Wheezing Severe Rhinovirus Illnesses During Infancy Predict Childhood Asthma at Age 6 Years

K. A. Roberg ¹, K. T. Sullivan-Dillie², M. D. Evans², T. E. Pappas², E. L. Anderson², K. M. Hanson², D. F. DaSilva², C. J. Tisler², L. E. P. Salazar², R. E. Gangnon², J. E. Gern², R. F. Lemanske, Jr.²; ¹University of Wisconsin School of Medicine and Public Health, Madison, WI, ²UW School of Medicine and Public Health, Madison, WI.

620   Epigenetic Regulation of Th1/Th2- Recall Responses in Atopic Asthmatic Individuals

R. Su ¹, A. Becker^1,2, A. L. Kozyrskyj^2,3, K. T. HayGlass^1,2; ¹CIHR National Training Program in Allergy and Asthma Research, Departments of Immunology, University of Manitoba, Winnipeg, MB, CANADA, ²Community Health Sciences, Winnipeg, MB, CANADA, ³Pediatrics/Child Health, Winnipeg, MB, CANADA.

Featured Poster Session

3804

Sunday, February 25, 2007

5:30 PM - 6:30 PM

All About Peanuts

621   Peanut Allergy in Infant: is Breastfeeding a Risk Factor?

A. Des Roches ¹, L. Paradis¹, J. Paradis¹, C. Infante-Rivard²; ¹Allergy Section, Hôpital Sainte-Justine, Montréal, PQ, CANADA, ²Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, PQ, CANADA.

622   Oral Peanut Immunotherapy For Peanut Allergic Patients

S. D. Nash ¹, P. H. Steele¹, J. S. Kamilaris¹, L. Pons¹, M. Kulis¹, L. A. Lee¹, K. Althage², L. Christie², A. M. Scurlock², S. M. Jones², A. W. Burks¹; ¹Duke University Medical Center, Durham, NC, ²University of Arkansas Medical Sciences, Little Rock, AR.

623   Minimum Elicitation Dose Determination Using Roasted Peanut-Low Dose Challenges

J. A. Nordlee ¹, S. L. Hefle¹, S. L. Taylor¹, A. C. Knulst², K. A. B. M. Peeters², R. K. Bush³, J. O. Hourihane⁴, D. A. Moneret-Vautrin⁵, M. Morisset⁵, P. S. Smailes³, C. A. Swenson³, J. B. T. Trewin⁶; ¹University of Nebraska, Lincoln, NE, ²University Medical Center, Utrecht, THE NETHERLANDS, ³University of Wisconsin Medical School, Madison, WI, ⁴University of Southampton School of Medicine, Southampton, UNITED KINGDOM, ⁵Hopital Universitaire, Nancy, FRANCE, ⁶Wellcome Trust Clinical Research Facility, Southampton, UNITED KINGDOM.

624   Clinical Features and Outcomes of Peanut-Allergic Patients Who Underwent Follow-up Oral Food Challenges

J. M. Maloney, W. G. Shreffler, S. H. Sicherer, H. A. Sampson; Mount Sinai Medical Center, New York, NY.

625   Clinical Predictors of Peanut Allergy Remission in Children

K. J. Allen ¹, M. Ho¹, R. Heine¹, W. Wong², C. Hosking¹, D. Hill¹; ¹Royal Children's Hospital, Parkville, AUSTRALIA, ²The University of Hong Kong, Hong Kong SAR, CHINA.

Featured Poster Session

3805

Sunday, February 25, 2007

5:30 PM - 6:30 PM

The Best of HCEDQ

626   Allergy Immunotherapy Practice Patterns and Associated Outcomes of Care

C. S. Hankin ¹, L. Cox², Z. Wang¹, A. Bronstone¹; ¹BioMedEcon, South San Francisco, CA, ²Nova Southeastern University School of Osteopathic Medicine, Davie, FL.

627   Physician and Patient Perception Differ for Symptoms Associated with Allergic Rhinitis (AR)

A. E. Williams ¹, M. Schatz², S. Kay³; ¹GlaxoSmithKline R&D, London, UNITED KINGDOM, ²Allergy Department, Kaiser-Permanente Medical Center, San Diego, CA, ³Adelphi Group Products, Macclesfield, UNITED KINGDOM.

628   Corticosteroid-Sparing Effects of Mepolizumab, an Anti-Interleukin-5 Monoclonal Antibody, in Patients With Hypereosinophilic Syndrome

L. J. Rosenwasser ¹, L. B. Schwartz², J. Sheikh³, A. D. Klion⁴, M. E. Rothenberg, on behalf of the Mepolizumab HES Study⁵; ¹Allergy-Immunology Division, Children's Mercy Hospital, Kansas City, MO, ²Department of Internal Medicine, Virginia Commonwealth University, Richmond, VA, ³Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, ⁴Laboratory of Parasitic Diseases, National Institutes of Health, Bethesda, MD, ⁵Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

629   Persistence and Compliance with Omalizumab in a Managed-Care Population

B. Gutierrez; Partnership for Health Analytic Research, Los Angeles, CA.

630   How Readable are our Patient Information Leaflets?

H. E. Smith, J. Wade, A. Frew; Brighton & Sussex Medical School, Brighton, UNITED KINGDOM.

Featured Poster Session

3806

Sunday, February 25, 2007

5:30 PM - 6:30 PM

T Cells and Allergic Inflammation

631   Onset of Clinical Tolerance to Milk Protein is Associated with Increased CD25+ CD27+ Casein Specific T Cells

W. G. Shreffler, N. Wanich, S. Noon, A. Nowak-Wegrzyn, H. A. Sampson; Mount Sinai School of Medicine, New York, NY.

632   Human Airway Epithelial Cells Produce Thymic Stromal Lymphopoietin (TSLP) after Stimulation with Th2 Cytokines and TLR3 Ligand

A. Kato, R. P. Schleimer; Allergy-Immunology Division, Northwestern University Feinberg School of Medicine, Chicago, IL.

633   Programmed Death One (PD1): Friend or a Foe of Regulatory T cells in the Modulation of Immune Response in Allergic Asthma

H. S. McGee ¹, H. Yagita², D. K. Agrawal³; ¹Creighton University, Department of Biomedical Sciences, Omaha, NE, ²Juntendo University School of Medicine, Department of Immunology, Toyko, JAPAN, ³Creighton University, Departments of Biomedical Sciences, Internal Medicine, Medical Microbiology and Immunology, Omaha, NE.

634   A Novel Adhesion Molecule Plays a Critical Role in T Cell Migration to Inflamed Skin

M. E. Gainers ^1,2, L. Descheny^1,2, C. J. Dimitroff^1,2; ¹Harvard Skin Disease Research Center, Boston, MA, ²Brigham and Women's Hospital, Boston, MA.

635   IL-4 Upregulates FceRI-Mediated TSLP Expression by Human Mast Cells

Y. Okayama ¹, H. Sagara², S. Okumura^1,3, K. Yuki¹, T. Fukuda², H. Saito¹; ¹RIKEN Yokohama Institute, Yokohama, JAPAN, ²Dokkyo University School of Medicine, Mibu, JAPAN, ³Stanford University School of Medicine, Stanford, CA.

Featured Poster Session

3807

Sunday, February 25, 2007

5:30 PM - 6:30 PM

Upper Airway Allergic and Inflammatory Disease: Searching for Causes and Connections

636   Effect of Allergen Challenge on Key Inflammatory Mediator Receptors Expression in Rat Nasal Tissues

N. Ferrari ¹, J. Brault¹, J. G. Wagner², M. Fortin¹, J. R. Harkema², P. M. Renzi¹, L. Paquet¹; ¹Topigen Pharmaceuticals Inc., Montreal, PQ, CANADA, ²Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI.

637   Nasal Ocular Reflexes Occur After Nasal Challenge With Allergen

F. M. Baroody, K. Foster, A. Markarian, M. deTineo, R. Naclerio; The University of Chicago, Chicago, IL.

638   Cytokines, Growth Factors And MMPs In Tears Of Vernal Keratoconjunctivitis (VKC) Patients

A. Leonardi ¹, M. Bortolotti¹, V. Calder², J. S. Curnow³, S. Sathe⁴, R. Sack⁴; ¹University of Padua, Padova, ITALY, ²UCL, London, UNITED KINGDOM, ³University of Birmingham, Birmingham, UNITED KINGDOM, ⁴SUNY College of Optometry, New York, NY.

639   Is Allergic Fungal Sinusitis A Distinct Form Of Chronic Rhinosinusitis?

P. S. Hutcheson ¹, M. S. Schubert², R. G. Slavin¹; ¹Saint Louis University Medical School, Saint Louis, MO, ²Allergy Asthma Clinic, Ltd., Phoenix, AZ.

640   Non Allergic Rhinitis In Competitive Swimmers

M. Gelardi ¹, M. Bonini^2,3, S. Bonini^3,4, T. Candreva¹, M. Fiorella¹, M. Ventura⁵; ¹Dept. of Ophthalmology and Otolaryngology, University of Bari, Bari, ITALY, ²Institute of Sports Medicine, UCSC, Rome, ITALY, ³CNR, Institute of Neurobiology and Molecular Medicine, Rome, ITALY, ⁴Chair of Allergy and Clinical Immunology, Second University of Naples, Naples, ITALY, ⁵Dept. of Internal Medicine, MIDIM, University of Bari, Bari, ITALY.

Poster Session

4201

Monday, February 26, 2007

9:45 AM - 10:45 AM

Epidemiology of Asthma

641   The Growing Gender Gap In Adult Asthma Hospitalizations: New York State 1990-2004

R. Y. Lin ^1,2; ¹St Vincents Hospital, Manhattan-SVCMC, New York, NY, ²New York Medical College, Valhalla, NY.

642   The Relationship Between Wheezing Patterns During Early Childhood and Six Year Asthma Diagnosis in a High Risk Birth Cohort

K. M. Hanson, M. D. Evans, C. J. Tisler, D. F. DaSilva, T. E. Pappas, R. A. Grabher, L. E. P. Salazar, K. T. Sullivan Dillie, E. L. Anderson, K. A. Roberg, R. E. Gangnon, J. E. Gern, R. F. Lemanske, Jr.; University of Wisconsin School of Medicine and Public Health, Madison, WI.

643   Caesarean Delivery Could Be A Risk Factor For Asthma?

C. Nunes, S. Ladeira; Center of Allergy of Algarve, Portimao, PORTUGAL.

644   Dog Ownership: A Risk Factor Of Corticosteroid-Resistant (CR) Asthma?

P. J. Hauk, E. Goleva, A. H. Liu, C. F. Hall, R. J. Martin, D. Y. M. Leung; National Jewish Medical and Research Center, Denver, CO.

645   Development of a Specific Questionnaire for the Suspicion of DPV

P. Giavina-Bianchi, L. Eduardo Pinto, S. Sayed, A. Cukier, J. Kalil; FMUSP, São Paulo, BRAZIL.

646   The Effect of Body Mass Index on Asthma Related Quality of Life Measurements in Children

B. Catalina; Long Island College Hospital, Brooklyn, NY.

647   Asthma, Obesity, And The Effect On Airway Inflammation

P. Sakali, A. Arreh-mensah, J. Estrada, P. Rojas, O. Ozdemir, K. Paris, C. Moore; Louisiana State University, New Orleans, LA.

648   Demographic Characteristics of Males and Females With Acute Asthma

I. Warrier, A. P. Baptist; Wayne State University, Detroit, MI.

649   Perinatal outcomes (PO), potencial pregnancy variables (PPV), comorbidity occurence (CO) and asthma severity in two successive pregnancies (2SP)

B. Novotna ^1,1, T. Pavlik²; ¹University Hospital, Brno, CZECH REPUBLIC, ²The Center of Biostatistics and Analyses Masaryk University, Brno, CZECH REPUBLIC.

650   The Role Of Fungi In Patient With Chronic Sinusitis And Bronchial Asthma

T. Hofman, A. M. Hofman, J. Michalik; Center of Allergology, Poznan, POLAND.

651   The Correlation Between Skin Prick Tests and Bronchial Hyperresponsiveness in Children with Atopic Conditions

J. J. Liem ¹, R. Rabbani², A. L. Kozyrskyj¹, A. B. Becker¹; ¹University of Manitoba, Winnipeg, MB, CANADA, ²The Manitoba Institute of Child Health, Winnipeg, MB, CANADA.

652   Comparison Of ΔFVC (% Fall In FVC At The Methacholine PC20) Between Asymptomatic And Symptomatic BHR

Y. Yoo ¹, J. Choung¹, J. Yu², S. Choi³, Y. Koh³; ¹Korea University Anam Hospital, Seoul, REPUBLIC OF KOREA, ²Dongguk University International Hospital, Goyang, REPUBLIC OF KOREA, ³Seoul National University Hospital, Seoul, REPUBLIC OF KOREA.

653   Respiratory Symptoms, Spirometry and Skin-Prick Tests in Patients with a Family History of Asthma: A 12-year Follow-up

J. P. Raasch; University of Minnesota, Minneapolis, MN.

654   Prevalence of Asthma among Childrend and Teenagers in Quito Ecuador

S. F. Barba, Jr.; Hospital General FF AA, QUITO, ECUADOR.

655   Prevalence and Factors affecting Asthma and Allergic Rhinitis among Adolescent children in Mysore, South India

P. A. Mahesh ¹, R. Bharath², A. D. Holla², A. K. Prabhakar², P. K. Vedanthan³; ¹JSS Medical College, Mysore, Karnataka, INDIA, ²Allergy Asthma and Chest Center, Mysore, Karnataka, INDIA, ³University of Colorado Health Sciences, Denver, CO.

656   Prevalence Of Asthma And Allergic Rhinitis In Children And Adolescents Of Nuevo Leon, Mexico

A. Arias-Cruz, M. Zárate-Hernández, S. N. González-Díaz, S. N. González-Díaz; Hospital Universitario, Monterrey, MEXICO.

657   Persistent Cough: The Link Between Asthma and Chlamydia pneumoniae Respiratory Infections

M. G. Ghoshhajra, A. A. Petrov; University of Pittsburgh Medical Center, Pittsburgh, PA.

658   Asthma at 6 Yrs is Not Associated with Overweight Status or Pro-Inflammatory Markers in a High-Risk-for-Asthma Birth Cohort

S. L. Friedlander, K. A. Roberg, M. D. Evans, R. E. Gangnon, Z. Zhang, H. J. Lai, J. E. Gern, R. F. Lemanske, Jr.; University WI - Madison, Madison, WI.

659   Children with Viral Respiratory Infections in the First Year of Life and Food Allergy at Age 5 Years

E. L. Anderson, K. S. Dillie, M. D. Evans, K. A. Roberg, L. E. P. Salazar, D. F. DaSilva, T. E. Pappas, C. J. Tisler, R. Gangnon, C. Ober, J. E. Gern, R. F. Lemanske, Jr.; University of Wisconsin School of Medicine and Public Health, Madison, WI.

660   Parental Smoking Modifies Effects Of Genetic Variation In Tumor Necrosis Factor-α On Childhood Asthma

H. Wu ¹, I. Romieu², J. Sienra-Monge³, B. Rio-Navarro³, D. M. Anderson¹, E. W. Dunn¹, L. L. Steiner⁴, I. Lara-Sanchez², S. London¹; ¹National Institute of Environmental Health Sciences, Research Triangle Park, NC, ²National Institute of Public Health, Cuernavaca, MEXICO, ³Hospital Infantil de Mexico Federico Gomez, Mexico City, MEXICO, ⁴Roche Molecular Systems, Alameda, CA.

661   Interactions Between Rhinovirus-Induced IFN-alpha Production at Birth and the Severity of Rhinovirus Illnesses in the First Year of Life

D. F. G. DaSilva, C. J. Tisler, T. E. Pappas, M. D. Evans, K. T. Sullivan Dillie, K. A. Roberg, E. L. Anderson, L. E. P. Salazar, R. A. Grabher, K. M. Hanson, R. E. Gangnon, J. E. Gern, R. F. Lemanske, Jr.; University of Wisconsin - Madison, Madison, WI.

662   Frequent Moderate to Severe Viral Respiratory Illnesses During Infancy Significantly Influence the Development of Asthma but Not Immunologic and Clinical Markers of Atopy During Early Childhood

R. A. Grabher, K. T. Sullivan Dillie, T. E. Pappas, D. F. DaSilva, K. A. Roberg, E. L. Anderson, K. M. Hanson, L. E. P. Salazar, C. J. Tisler, M. D. Evans, R. E. Gangnon, J. E. Gern, R. F. Lemanske, Jr.; University of Wisconsin School of Medicine and Public Health, Madison, WI.

663   Association of Environmental Allergen Sensitization with Asthma Morbidity

J. Wang ¹, C. M. Visness², A. Calatroni², P. J. Gergen³, H. E. Mitchell², H. A. Sampson¹; ¹Mount Sinai Medical Center, New York, NY, ²Rho Federal Systems Division, Inc, Chapel Hill, NC, ³National Institutes of Allergy and Infectious Disease, National Institutes of Health, Bethesda, MD.

664   Factors Associated with Asthma Mortality: a National United Kingdom Database Analysis

L. Watson ¹, F. Turk², S. T. Holgate³; ¹Phimap, Bollington, Cheshire, UNITED KINGDOM, ²Novartis Pharma, Basel, SWITZERLAND, ³Southampton University Hospital, Southampton, UNITED KINGDOM.

665   Influence of Body Mass Index on Lung Function in Korean Children With No Asthma Symptoms Residing in Urban Area

Y. H. Shin ¹, K. W. Kim², K. E. Kim¹, H. Y. Yum¹, K. E. Lee², T. W. Song², E. S. Kim², M. H. Sohn², K. E. Kim²; ¹Pochon CHA University College of Medicine, Seoul, REPUBLIC OF KOREA, ²Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA.

666   The First Nationwide Survey of Asthma Prevalence in Japan using ISAAC and ECRHS questionnaire

A. Akasawa ¹, M. Akashi¹, A. Aota¹, A. Saito¹, N. Kojima¹, M. Futamura¹, Y. Ohya¹, Y. Adachi², H. Odajima³, K. Takahashi⁴, T. Nakagawa⁵, K. Akiyama⁶; ¹National Ctr for Child Health and Development, Tokyo, JAPAN, ²Toyama Medical and Pharmaceutical University, Toyama, JAPAN, ³NHO Fukuoka National Hospital, Fukuoka, JAPAN, ⁴NHO Minami-Okayama Medical Center, Okayama, JAPAN, ⁵Kawasaki Municipal Tama Hospital, Kanagawa, JAPAN, ⁶NHO Sagamihara National Hospital, Kanagawa, JAPAN.

667   Risk Factors for Fatal Asthma in Three U.S. States, 2004

C. A. Camargo, Jr. ¹, A. J. Pelletier¹, R. Hammel², D. Vasas³, D. M. Lang³; ¹Massachusetts General Hospital, Boston, MA, ²University of Arkansas Medical Sciences, Little Rock, AR, ³Cleveland Clinic, Cleveland, OH.

668   Advair Prescribing Patterns in a State Medicaid and Child Health Insurance Program

M. E. Helm ¹, P. A. Vargas², S. M. Jones²; ¹University of Arkansas for Medical Sciences, Little Rock, AR, ²University of Arkansas for Medical Sciences/Arkansas Children's Hospital Research Institute, Little Rock, AR.

669   Comorbidity of Life-Threatening Arrhythmia in Children with Asthma

Y. Ito, Y. Adachi, T. Itazawa, K. Saito, K. Uese, F. Ichida, T. Miyawaki; University of Toyama, Toyama, JAPAN.

670   Electrocardiograph (ekgs) And Echocardiograph (ecos) Alterations Determined And Compared In Obese Adolescents With Asthma (oa) And Without Asthma (ona) (preliminary Results)

J. S. Calderon Rivera, B. E. del Rio Navarro, J. J. L. Sienra Monge; Hospital Infantil de Mexico, Federico Gomez, Mexico City, MEXICO.

Poster Session

4202

Monday, February 26, 2007

9:45 AM - 10:45 AM

Miscellaneous/Potpourri from ADT

671   Genetic Association between Asthma and Atopy and CD14 Promoter Variants in Chinese Children

Y. S. Wong¹, T. F. Leung ¹, C. Y. Li¹, I. H. S. Chan², E. Yung¹, C. W. K. Lam², G. W. K. Wong¹; ¹Department of Pediatrics, The Chinese University of Hong Kong, Hong Kong, HONG KONG, ²Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, HONG KONG.

672   TNFA -308 G/A Polymorphism And Asthma In Different Ethnicities: Systematic Review and Meta-analysis

I. R. Genov, A. Gonçalves-Primo, D. Solé, C. K. Naspitz; UNIFESP, São Paulo, BRAZIL.

673   Synergistic Modulation Of Eotaxin And Il-4 Secretion By Constituents Of An Anti-asthma Herbal Formula (ashmi) In Vitro

J. Bolleddula; Mount Sinai School of Medicine, New York, NY.

674   Development of a Cell Culture Model for the Study of Genes Regulated by Inhaled Corticoids During Asthma Treatment

C. J. Pantoja; University of California, San Francisco, San Francisco, CA.

675   Safety and Tolerance of a Novel Medical Food (NMF) in Children with Mild Persistent Asthma

S. J. Szefler ¹, R. Covar¹, B. Macomber¹, L. Stewart¹, M. Gleason¹, K. Engelhardt¹, J. Murphy¹, A. Liu¹, S. Wood², S. DeMichele², A. Wennberg², E. Gelfand¹; ¹National Jewish Med Res Ctr, Denver, CO, ²Ross Products, Abbott Laboratories, Columbus, OH.

676   Harnessing the RNA-interference for Anti-inflammatory Therapeutics

P. N. Pushparaj ¹, J. J. Aarthi², S. D. Kumar¹; ¹National University of Singapore, Singapore, SINGAPORE, ²Singapore General Hospital, Singapore, SINGAPORE.

677   Rescue-Free and Symptom-Free Days With Mometasone Furoate Dry Powder Inhaler Used Once or Twice Daily in the Evening by Patients With Persistent Asthma

G. W. Bensch ¹, J. Corren², R. Lockey³, R. Yao⁴, H. Staudinger⁴; ¹Allergy, Immunology and Asthma Medical Group, Stockton, CA, ²Allergy Research Foundation, Inc., Los Angeles, CA, ³University of South Florida College of Medicine, Tampa, FL, ⁴Schering-Plough Research Institute, Kenilworth, NJ.

678   A Case Study; Extracorporeal Gas Exchange for Severe Asthma Treatment

Y. Ogawa, E. G. Brooks, L. Williams, J. Lynch, J. B. Zwischenberger; University of Texas Medical Branch, Galveston, TX.

679   Diffuse Idiopathic Pulmonary Neuroendocrine Cell Hyperplasia (DIPNECH) in a Patient with Cough and Dyspnea Resistant to Standard Therapy

N. Singhania, Q. Liang, C. Cool, R. Tate, R. Alam; National Jewish Medical and Research Center, Denver, CO.

680   Management of Asthma Exacerbation in a Patient with Wiskott Aldrich Syndrome

M. A. Rank, J. B. Hagan; Mayo Clinic, Rochester, MN.

681   A Tale of Two Pediatric Patients: Using High Resolution CT (HRCT) to Distinguish Severe Asthma and Bronchiolitis Obliterans (BO)

P. A. Szefler, M. E. Krawiec, J. D. Newell, S. J. Szefler, R. W. Hendershot; National Jewish Medical and Research Center, Denver, CO.

682   A Case Study Utilizing Exhaled Nitric Oxide - An Aid in Determining Asthma Treatment

J. Bishop, B. Miller; Univeristy of Kentucky, Lexington, KY.

Poster Session

4203

Monday, February 26, 2007

9:45 AM - 10:45 AM

Immunogenetics and Other BCI

683   Correlation of Plasma Ghrelin And Serum Immunoglobulin Levels: A Hormonal Link Between Immunity and Obesity?

K. Matsuda, Y. Okamatsu, H. Tani, K. Kimura, T. Matsuishi; Kurume university school of medicine, Kurume ciry, Fukuoka, JAPAN.

684   Association of a Haplotype Related to TGFb1 with Allergy and Its Potential Race Dependent Effect

J. Meng; Children's Mercy Hospital, UMKC School of Medicine, Kansas City, MO.

685   A Genetic Variant in the Promoter of the Siglec8 Gene is Associated with Wheeze in a Brazilian Population

A. V. Grant ^1,2, B. S. Bochner², J. P. Guo², M. I. Araujo³, E. V. Ponte⁴, A. A. Cruz⁴, T. H. Beaty¹, P. S. Gao²; ¹Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ²Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD, ³Servico de Imunologia, Hospital Universitario Professor Edgard Santos, Salvador, BRAZIL, ⁴Brazil Center for Respiratory Diseases, Federal University of Bahia, Salvador, BRAZIL.

686   A Network-based Analysis Of Lung From A Novel Mouse Model Of Experimental Asthma

S. B. Sarpong ¹, S. Ghimbovschi², E. Hoffman²; ¹Howard University, Washington, DC, ²Childrens National Medical Center, Washington, DC.

687   A G-protein-coupled Receptor 154 (GPRA) Gene Polymorphism is Associated with Asthma in a Colombian population

C. Vergara ¹, N. Acevedo¹, S. Jiménez¹, B. Martínez¹, L. Gusmão², D. Mercado¹, L. Caraballo¹; ¹Institute for Immunological Research, University of Cartagena, Cartagena, COLOMBIA, ²IPATIMUP, Instituto de Patologia e Inmunologia Molecular da Universidade do Porto, Portugal, Porto, PORTUGAL.

688   The Interleukin 1β Gene (IL1B) is Upregulated in CD14+ Monocytes But Not Alveolar Macrophages after Lipopolysaccharide (LPS) Stimulation by Genomic Expression Profiling

Y. J. Tsai ¹, P. Gao¹, M. A. Williams², D. Grigoryev¹, M. Stockton¹, T. Watkins¹, C. Cheadle¹, S. Georas², M. C. Liu¹, L. Breslin¹, K. C. Barnes¹; ¹Johns Hopkins University, Baltimore, MD, ²University of Rochester, Rochester, NY.

689   GATA-3 Induces Transcriptional Activation of CRTh2

R. Quapp, T. Seibert, N. Madsen, K. Madsen, L. Cameron; University of Alberta, Edmonton, AB, CANADA.

690   Keratins: Important Candidate genes for Asthma and Immune Responsiveness to Cockroach

P. Gao ¹, D. Grigoryev¹, L. Breslin¹, C. Cheadle¹, R. A. Mathias², T. H. Beaty³, A. Togias¹, K. Barnes¹; ¹JHAAC, Baltimore, MD, ²Center for Inherited Disease Research, NIH, Baltimore, MD, ³Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD.

691   Copy Number Variations in del22q11.2 Syndrome

S. A. McGhee, M. Suchard, U. Bhardwaj, Y. Zhang, E. R. B. McCabe; David Geffen School of Medicine at UCLA, Los Angeles, CA.

692   Effect of Montelukast on IL6, IL12 from Inflamatory Exudation in Gouty Arthritis Model

J. A. Corado, M. Bermudez, A. Linares, L. Ponce, Z. Mora, J. Lucar, A. Acosta, R. Tovar; Universidad de Carabobo, Valencia, VENEZUELA.

693   Hydrodynamics Based in vivo siRNA Transfection: Legal or Lethal?

P. N. Pushparaj, H. S. Chen, A. J. Melendez; National University of Singapore, Singapore, SINGAPORE.

694   Prevalence Of IgE Anti-parvovirus B19 Antibodies In Asymptomatic Healthy Adult Humans

M. H. Bluth, H. G. Durkin, L. Wright, M. Nowakowski, T. A. Smith-Norowitz; SUNY Downstate Medical Center, Brooklyn, NY.

695   Detection Of IgE Anti-Parvovirus B19 Antibodies In Human Breast Millk: A Case Study

T. A. Smith-Norowitz, K. B. Norowitz, H. Drew, M. Nowakowski, E. F. Bluth, H. G. Durkin, M. H. Bluth; SUNY Downstate Medical Center, Center for Allergy and Asthma Research, Brooklyn, NY.

696   The Role of Surfactant Protein D (SP-D) and IgA in Schaedler's E.coli Induced Diminished Translocation of Lactobacillus salivarius Into the Lung: Crosstalk Between Innate and Adaptive Immunity

K. Krytska ^1,2, N. V. Boyko², N. Kushnir¹, D. Kobuley¹, S. A. Keilbaugh¹, G. D. Wu¹, Y. Yu¹, J. J. Cebra¹, A. Haczku¹; ¹University of Pennsylvania, Philadelphia, PA, ²Uzhgorod National University, Uzhgorod, UKRAINE.

697   Changes in Cytokine Levels in The First Year of Life in WHEALS Cohort Infants

K. R. Bobbitt, K. J. Woodcroft, S. Havstad, L. K. Williams, C. C. Johnson; Henry Ford Hospital, Detroit, MI.

698   Effect Of Nasal And Bronchial Grass Pollen Challenges On Plasma Cytokine Levels

C. Barnig ¹, B. Uring-Lambert², A. Purohit¹, C. Donnay¹, A. Casset¹, S. Bahram², F. de Blay¹; ¹Asthma and Allergy Division, Department of Chest Diseases,University Hospital, Strasbourg, FRANCE, ²Laboratory of Immunology, University Hospital, Strasbourg, FRANCE.

699   Influence Of H1, H2 And H3 Antagonists On Apoptosis Of Lymphoid Cells

I. Kaidashev ¹, I. Yastremskaya¹, N. Kutzenko¹, L. M. DuBuske²; ¹Ukrainian Medical Stomatological Academy, Poltava, UKRAINE, ²Immunology Research Institute of New England, Gardner, MA.

700   Leukemoid Reaction in Children: Lymphocytes Flow Cytometry Characterization and Clinical Etiologies

A. Beigelman ^1,2, J. Kapelushnik¹, G. Shubinsky¹, A. Haim¹, A. M. Moser¹; ¹Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, ISRAEL, ²Washington University School of Medicine, Saint Louis, MO.

701   Inhibition of Phosphoinositide 3 Kinase by Masoprocol Ameliorates IgE-mediated Anaphylaxis in vivo and ex vivo

J. J. A. Aarthi ¹, P. N. Pushparaj², S. D. Kumar²; ¹Singapore General Hospital, Singapore, SINGAPORE, ²National University of Singapore, Singapore, SINGAPORE.

702   Altered Histone Acetylation in Monocytes in Response to Polarization with IFN-gamma and IL-4

S. L. Garrett ^1,2, K. Sullivan¹; ¹Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA.

703   Macrophages Accumulation in Visceral and Subcutaneous Adipose Tissue Correlates with Age

E. Jerschow ¹, S. Anwar², N. Barzilai¹, D. Rosenstreich¹; ¹Albert Einstien College Medicine, Bronx, NY, ²Montefiore Medical Center, Bronx, NY.

704   The Role Of c-FLIP Isoform II In Il-2 Production

B. K. Al-Saud, Z. Alli, M. Abdelhaleem; the hospital for sick children, Toronto, ON, CANADA.

Poster Session

4204

Monday, February 26, 2007

9:45 AM - 10:45 AM

Immunodeficiency II and HIV

705   Pattern Of Cd28 Expression On Cd8+ T Cells In A Group Of Coinfected And Monoinfected HIV And HCV Patients

A. Paravisini ¹, M. S. Cianchetta¹, R. Garcia¹, S. Raso², P. Llorente¹, M. Fernandez-Guerrero³, M. Gorgolas³; ¹Immunology.Fundacion Jimenez Diaz Capio, Madrid, SPAIN, ²Immunology.Fundacion Jimenez Diaz Unilabs, Madrid, SPAIN, ³Infectious Diseases.Fundacion Jimenez Diaz Capio, Madrid, SPAIN.

706   Multidrug-Resistant (MDR) HIV Transmission to a Third Generation Offspring

D. W. Rosenthal ^1,2, C. Colter¹, L. Maroldo³, E. Coakley³, S. J. Schuval¹; ¹Long Island Jewish Medical Center, Schneider Children's Hosptial, New Hyde Park, NY, ²Feinstein Institute for Medical Research at North Shore Long Island Jewish Health System, Manhasset, NY, ³Mongram Biosciences, South San Francisco, CA.

707   A Protocol for the Desensitization to Intravenous Immunoglobulin (IVIg)

M. Salomon, R. Hostoffer, Jr.; Case Western Reserve University, Cleveland, OH.

708   3 Cases of Common Variable Immune Deficiency Associated With Absence of CD19+ B Lymphocytes

J. R. Sigmon, E. Kasabeh, G. Krishnaswamy; Division of Allergy and Immunology, Department of Internal Medicine, East Tennessee State University, College of Medicine, Johnson City, TN.

709   Intrathoracic Disease and Nontuberculous Mycobacteria (NTM) in a 6 Month Old Female: Immunodeficiency or Bad Luck? Case Report/Proposal

D. M. Anmuth ¹, M. S. Edwards¹, N. Tatevian¹, S. M. Holland², I. C. Hanson¹; ¹Baylor College of Medicine/Texas Children's Hospital, Houston, TX, ²National Institute of Allergy and Infectious Diseases, Bethesda, MD.

710   Lymphomatoid Granulomatosis in a Young Male with Hypogammagobulinemia

M. A. Netravali ¹, A. J. MacGinnitie¹, L. Teot², D. R. Nash¹; ¹Children's Hospital of Pittsburgh, Pittsburgh, PA, ²University of Pittsburgh Medical Center, Pittsburgh, PA.

711   Myocardial Infarction After Replacement-Dose Intravenous Immunoglobulin

J. M. Klein ¹, A. Tevrizian², D. Adelman¹, P. Avila³; ¹University of California, San Francisco, San Francisco, CA, ²Allergy and Asthma Medical Group of the Bay Area, Pleasanton, CA, ³Northwestern University, Chicago, IL.

712   Specific Antibody Deficiency in a Patient with Factor IX Deficiency

M. A. Travassos, S. W. Alexander, J. E. Arnold, A. K. Chouksey; Rainbow Babies & Children's Hospital, Cleveland, OH.

713   Mannose Binding Lectin Deficiency In An Adolescent With Recurrent Infections And Idiopathic Thrombocytopenic Purpura

S. M. Nyenhuis, J. E. Gern; Department of Medicine, Section of Allergy and Clinical Immunology, University of Wisconsin, Madison, WI.

714   Atypical Presentation of DiGeorge Syndrome in an 14 Year Old Male

S. Najm Masoud, W. Blouin, R. A. Stoudt, J. Carro, V. P. Hernandez-Trujillo; Miami Children's Hospital, Miami, FL.

715   Cystic Fibrosis and Associated Common Variable Immunodeficiency

M. M. Sikora, R. Bansal, J. El-Dahr; Tulane University, New Orleans, LA.

716   Improved Tolerability with IVIG Switch in Patients With Common Variable Immunodeficiency

H. N. Taki ^1,2, H. Karen¹; ¹Fort Wayne Medical Institute, Fort Wayne, IN, ²Medical Universilty of Ohio, Toledo, OH.

717   Neutropenia And Primary Immunodeficiency Disease (PID)

S. N. Mathew; University of New Mexico, Albuquerque, NM.

718   Food Allergy in a Patient with Hyper-IgE Syndrome (HIE) in Exclusive Breast-Feeding

A. M. S. Neves ¹, P. A. Cunha², T. Lawrence¹, S. S. Lima³, M. C. Mallozi⁴, B. T. Costa-Carvalho⁴, D. Solé⁵; ¹Fellow in Training of the Division of Allergy, Clinical Immunology, and Rheumatology of the Department of Pediatrics, Federal University of São Paulo-Escola Paulista de Medicine, São Paulo, BRAZIL, ²Felow in Training of the Division of Pediatric DermatologyHospital Darcy Vargas, São Paulo, BRAZIL., São Paulo, BRAZIL, ³Professor of the Division of Pediatric Dermatology, Hospital Darcy Vargas, São Paulo, BRAZIL, ⁴Associate Professor of the Division of Allergy, Clinical Immunology, and Rheumatology of the Department of Pediatrics, Federal University of São Paulo-Escola Paulista de Medicine, São Paulo, BRAZIL, ⁵Full Professor of the Division of Allergy, Clinical Immunology, and Rheumatology of the Department of Pediatrics,Federal University of São Paulo-Escola Paulista de Medicine, São Paulo, BRAZIL.

719   Relationship Of Immune Response To Endotoxin And Candida To Clinical Status Of Patients With Combined Bacterial And Candidal Periodontitis

V. A. Beloglazov ¹, N. S. Lukojanova¹, A. I. G_rdienko¹, N. V. Khimich¹, A. A. Bakova¹, I. V. DuBuske², L. M. DuBuske²; ¹Crimean Medical State University, Simferopol, UKRAINE, ²Immunology Research Institute of New England, Gardner, MA.

720   Transient Neonatal Hypocalcemic Seizures Identifying Partial DiGeorge Syndrome

S. Ramanuja, D. C. Jerome, M. R. Baskin; University of California at Irvine, Irvine, CA.

721   The Role of IVIG in Treatment of Hyper-IgE Syndrome (HIES)

S. I. Krassilnikova, M. Davies, J. Rosch; Penn State's Milton S. Hershey Medical Center, Hershey, PA.

722   Primary Selective IgM Deficiency (SIgMD) Associated With Functional Antibody Deficiency In Two Boys

F. I. Khan, M. Pansare, E. A. Secord; Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI.

723   14 Year Old Boy With ill-defined Immunodeficiency

R. S. Watkins ¹, A. L. MacDowell¹, M. Fontana-Penn¹, S. De Ravin², H. L. Malech²; ¹Wake Forest University Baptist Med. Ctr., Winston Salem, NC, ²National Institute of Allergy and Infectious Diseases; National Institutes of Health, Bethesda, MD.

724   An Adolescent Patient with Chronic Granulomatous Disease (CGD) Presenting with Renal Failure

P. D. Niolet, K. Paris, C. Moore; LSU Health Sciences Center, New Orleans, LA.

725   Positive Prick Test in an X-Linked Agammaglobulinemia Patient

T. C. Lawrence; UNIFESP-EPM, São Paulo, BRAZIL.

726   A 3 Years Old Female With SCID T(-) B(-) Nk(+) Treated With Halogenic Bone Marrow Transplantation. Case Report

H. Del Olmo Tellez, G. Treviño Garza, N. Ramire, C. Ramos Becerril, F. Rivas Larrauri; National Institute of Pediatrics Mexico, Mexico City, MEXICO.

727   Case Report. Recessive Pediatric Hyper Ige Syndrome

K. I. G. C. Giron, II, A. A. S. Alcantara, III, H. G. C. Campos, IV, S. E. E. P. Espinosa, Jr.; National Institute of Pediatric, Mexico D.F, MEXICO.

Poster Session

4205

Monday, February 26, 2007

9:45 AM - 10:45 AM

Airborne Allergens, Environmental Exposure Assessment and Abatement

728   A Quantitative Exposure Assessment for Eight Indoor Allergens by Fluorescent Multiplex Array

C. D. Earle ¹, A. Tsay¹, K. Pittman¹, L. Vailes¹, R. Godbout², K. G. Oliver³, M. D. Chapman¹; ¹Indoor Biotechnologies Inc., Charlottesville, VA, ²Radix Biosolutions Inc., Austin, TX, ³Radix Biosolutions Inc, Austin, TX.

729   The Risk of Asthma in Children Sensitized to Alternaria

R. Chooniedass ^1,2, R. Rabbani^1,2, J. Liem^1,2, A. Becker^1,2; ¹University of Manitoba, Winnipeg, MB, CANADA, ²Manitoba Institute of Child Health, Winnipeg, MB, CANADA.

730   Fel d 1 In The Bed Dust Of Cat Non-Owners Differs Among Ethnicities But Not Neighborhood In Two NYC Cohorts

K. Panjwani ^1,2, G. L. Chew¹, A. Divjan¹, A. M. Reardon¹, F. P. Perera¹, R. L. Miller¹, M. S. Perzanowski¹; ¹Columbia's Center for Children's Environmental Health (CCCEH), New York, NY, ²Department of Environmental Health Sciences, Columbia University, New York, NY.

731   Content of (1-3)-β-D-glucan in Common Indoor Air Fungi

Y. Iossifova, C. Crawford, T. Reponen; University of Cincinnati, Cincinnati, OH.

732   Comparison of Protein Antigens Among Commercially Available Dog Extracts

T. M. Hrabak, J. Dice, L. Hagan, B. Whisman; Wilford Hall Medical Center, Lackland AFB, TX.

733   Effects of Climate And Flooding On Mold And Pollen Sensitization

D. Dalan ¹, W. Brooks, IV², E. Levetin³; ¹University of North Dakota, Fargo, ND, ²Allergy & Asthma Care Center, Fargo, ND, ³Biological Science, University of Tulsa, Tulsa, OK.

734   Are There House-Dust Mites on Moldy Wall Surfaces?

Y. Gernez ¹, P. Parola¹, A. Palot¹, G. Maurel², J. Ercoli², C. Charpin-Kadouch², D. Charpin¹, H. Dumon¹; ¹Assistance publique-Hoˆpitaux de Marseille, Marseille, FRANCE, ²Maison de l'Allergie et de l'Environnement, Marseille, FRANCE.

735   Acute Asthma with High Grass Pollen in Oregon

K. W. Jacobson ¹, S. E. Zakarian¹, J. C. Jensen¹, J. A. Moran¹, M. Glovsky²; ¹Allergy and Asthma Research Group, Eugene, OR, ²California Institute of Technology, Pasadena, CA.

736   IgE Reactivity to Paecilomyces variotii Antigens in Fungal Sensitized Patients

B. J. Green ¹, F. M. Blachere¹, D. H. Beezhold¹, D. N. Weissman¹, M. B. Hogan², N. W. Wilson², D. Schmechel¹; ¹Centers for Disease Control and Prevention, Morgantown, WV, ²West Virginia University School of Medicine, Morgantown, WV.

737   Rat and Mouse Allergens in Homes of Patients with Acute Wheezing Living in Brazil

M. Thiesen¹, A. S. Zampolo¹, A. R. Santos¹, A. A. Camara², V. P. L. Ferriani¹, L. K. Arruda ¹; ¹School of Medicine of Ribeirão Preto-University of São Paulo, Ribeirão Preto, BRAZIL, ²Santa Lidia Hospital, Ribeirão Preto, BRAZIL.

738   Mites Whose Time Has Come: Sensitization to Blomia Tropicalis, and Other Mites in Allergic Patients in Israel

K. Sade, D. Roitman, S. Kivity; Tel-Aviv Sourasky Medical Center, Tel-Aviv, ISRAEL.

739   A Two-stage Personal Cyclone Sampler for the Collection of Fungal Aerosols and Direct ELISA and PCR Sample Analysis

D. Schmechel, W. G. Lindsley, T. B. Chen, F. M. Blachere, B. J. Green, R. A. Brundage, D. H. Beezhold; CDC/Natl. Inst. Occup. Safety & Health, Morgantown, WV.

740   Risk Factors and Distribution of Mite Allergens in Spain

V. Iraola, E. Fernández-Caldas; Laboratorios LETI S.L., Tres Cantos, SPAIN.

741   Relative Potency of Mold and House Dust Mite Extracts in Inducing Allergic Responses in BALB/c Mice

Y. Chung, L. B. Copeland, M. D. W. Ward; US/EPA, Research Triangle Park, NC.

742   Meteorological Effects May Alter the Incidence of Rye-grass Pollen Related Asthma

M. M. Glovsky ¹, K. Jacobson², S. Zakarian², J. Jensen², J. Moran², P. E. Taylor¹; ¹Huntington Asthma and Allergy Center, Pasadena, CA, ²Allergy and Asthma Research Group, Eugene, OR.

743   Home Cleaning Awareness Improves Asthma Quality Of Life

M. Amado, F. Pacheco, L. Gard, E. Forrest, L. Johnson, C. Barnes; Childrens Mercy Hospital, Kansas City, MO.

744   Reduction in Aspergillus and Penicillium Spore Counts Results in Reduction of Aspergillus and Penicillium Antigen Level in House Dust

D. R. Ward, P. Dowling, F. Hu, L. Johnson, K. Kennedy, C. Barnes; Children's Mercy Hospital, Kansas City, MO.

745   Initial Characterization of a cDNA Encoding a Heat Shock Protein Homolog From Stachybotrys chartarum

F. M. Blachere, B. J. Green, D. Schmechel, D. H. Beezhold; Centers for Disease Control and Prevention, Morgantown, WV.

746   The Relationship between Skin Test Responses and Nasal Responses to Mouse Allergen

H. P. Sharma, R. A. Wood, A. R. Bravo, E. C. Matsui; Johns Hopkins University, Baltimore, MD.

747   Statewide and Intrastate Assessments of Allergenic Tree, Grass and Weed Species

R. S. Jacobson, T. J. Grier; Greer Laboratories, Inc., Lenoir, NC.

748   Decreased Dust Antigen Levels Resulting from Specific Cleaning Practices

B. Jones, C. Barnes, F. Pacheco, L. Johnson, L. Gard, E. Forrest, J. Portnoy; Children's Mercy Hospital, Kansas City, MO.

749   The Impact of Cleaning Practices on Antigen Levels and Spirometry in an Asthmatic Population

C. S. Barnes, F. Pacheco, L. Gard, E. Forrest, L. Johnson, J. Portnoy; Childrens Mercy Hospital, Kansas City, MO.

Poster Session

4206

Monday, February 26, 2007

9:45 AM - 10:45 AM

Food Allergy III

750   Sensitization to Cor a 8, a Lipid Transfer Protein, in Children with Objective Reactions to Hazelnut from a Birch Endemic Country

A. E. Flinterman ¹, J. H. Akkerdaas^2,1, C. F. den Hartog Jager¹, M. O. Hoekstra¹, A. C. Knulst¹, R. van Ree², S. G. M. A. Pasmans¹; ¹University Medical Center, Utrecht, THE NETHERLANDS, ²Academic Medical Center, Amsterdam, THE NETHERLANDS.

751   Omega-5-Gliadin Specific IgE as a Predictor of Wheat Allergy in Children

K. Ito ¹, Y. Takaoka¹, M. Futamura¹, T. Sakamoto², K. Kohno³, E. Morita³, H. Matsuo⁴, A. Tanaka⁵; ¹Aichi Children's Health and Medical Center, Obu, JAPAN, ²Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, JAPAN, ³Department of Dermatology, Shimane University School of Medicine, Shimane, JAPAN, ⁴Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, JAPAN, ⁵Phadia KK., Tokyo, JAPAN.

752   Impact of an Inpatient Program to Improve Safety of Food Allergic Patients During Hospitalization

A. R. Auerbach ¹, M. E. Bollinger¹, E. Loreck², M. Simke², C. Vibbert¹, J. Gladstein¹, A. Kewalramani¹; ¹Univ. of Maryland School of Medicine, Baltimore, MD, ²Univ. of Maryland Medical System, Baltimore, MD.

753   Contamination of Probiotic Preparations With Milk Allergen Can Cause Anaphylaxis in Cow's Milk Allergic Patients

M. Morisset ¹, T. T. Lee², C. M. N. Astier³, D. A. Moneret-Vautrin¹, V. Cordebar¹, E. Beaudouin¹, F. Codreanu¹, B. E. Bihain⁴, G. Kanny¹; ¹University Hospital, Nancy, FRANCE, ²Laboratory of Molecular Medicine and Therapeutics, Vandoeuvre-Les-Nancy, FRANCE, ³INPL, Vandoeuvre-Les-Nancy, FRANCE, ⁴Laboratory of Molecular Medicine and Therapeutics, Nancy, FRANCE.

754   Usefulness Of Serum Interleukin-10 In The Determining Food Tolerance

F. Pineda; DIATER Laboratories, San Martin de la Vega, SPAIN.

755   Oral Food Challenge with Boiled Egg Yolk and Boiled and Raw Egg White

Y. Takaoka ¹, K. Ito¹, M. Futamura¹, T. Sakamoto²; ¹Aichi Children's Health and Medical Center, Obu, JAPAN, ²Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, JAPAN.

756   IgE Mediated Cow's Milk Allergy (CMA): Evaluation of Weight and Height of Patients at Admission and After one-year Follow-up in Use of Soy Products

G. H. Yonamine, G. A. Corradi, F. R. P. Afonso, A. P. B. M. Castro, A. C. Pastorino, C. M. A. Jacob; Depto. of Pediatrics, São Paulo, BRAZIL.

757   Detection of Legume Proteins Cross-reactivity by Immunoblot Using Human Plasma of Individuals with Food Allergies to Peanut and/or Soybean

L. Chen, A. O. Ofori-Anti, R. E. Goodman; University of Nebraska, Lincoln, NE.

758   Assessment Of The Allergenicity To Raw Tuna And Canned Tuna

Y. Kondo ¹, Y. Nakajima¹, R. Komatsubara¹, M. Kawamura¹, M. Kakami¹, I. Tsuge¹, T. Yasuda², A. Urisu¹; ¹Fujita Health University, Toyoake, Aichi, JAPAN, ²Toyo Suisan Kaisha, Ltd, Tokyo, JAPAN.

759   Ara H 2.02 Is A More Potent Cross-linker Of Anti-Peanut IgE Than Is Ara H 2.01

R. El Mezayen ¹, L. Pons², A. W. Burks², M. West³, S. Stanley³, M. El Gazzar¹, M. W. Duncan¹, K. C. Hansen¹, S. C. Dreskin¹; ¹University of Colorado Health Sciences Center, Denver, CO, ²Duke University, Durham, NC, ³University of Arkansas Medical Center, Little Rock, AR.

760   The Majority of the Effector Activity of a Crude Peanut Extract Co-purifies with Ara h 2 but not Ara h 1 or Ara h 3

H. S. Porterfield, M. W. Duncan, K. C. Hansen, S. C. Dreskin; University of Colorado Health Sciences Center, Denver, CO.

761   Diagnosis of Cow's Milk Allergy: Are Low Levels of Specific IgE Significant?

A. M. Plaza, M. Piquer, M. T. Giner, M. A. Martin Mateos, J. I. Sierra; Hospital Sant Joan de Déu, Esplugues, SPAIN.

762   An Objective Approach for the Assessment of Interchangeability of Cross-Reactive Food Allergens in Diagnostic Tests for Specific IgE

J. Lidholm ¹, A. Marknell DeWitt¹, L. Mattsson¹, J. Ostling¹, G. Lilja², M. Nordlund², B. Ballmer-Weber³, S. Scheurer⁴, A. Wangorsch⁴, H. Kofler⁵, J. Sastre⁶, E. Enrique⁷, S. Vieths⁴, K. Andersson¹; ¹Phadia AB, Uppsala, SWEDEN, ²Sachs' Children's Hospital, Stockholm, SWEDEN, ³University Hospital Zurich, Zurich, SWITZERLAND, ⁴Paul-Ehrlich-Institut, Langen, GERMANY, ⁵Allergieambulatorium Hall, Hall, AUSTRIA, ⁶Fundación Jiménez Díaz, Madrid, SPAIN, ⁷Hospital General de Castellón, Castellón, SPAIN.

763   Seasonal Palatal Pruritus is a Risk Factor for Oral Allergy Syndrome

D. A. Fischer; University of Western Ontario, Barrie, ON, CANADA.

764   A Trial of a Diet Containing Baked Egg in Children with Egg Allergy

A. H. Nowak-Wegrzyn, S. H. Sicherer, W. G. Shreffler, E. Thanik, S. Mofidi, S. Noone, H. A. Sampson; Jaffe Food Allergy Institute, Mount Sinai School of Medicine, New York, NY.

765   Dioscorea batatas (Sanyak) Allergy, Identification of an IgE-binding Component

G. Hur ¹, S. Shin², H. Park¹, H. Kim¹, Y. Ye¹, S. Kim³, D. Nahm¹, H. Park¹; ¹Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA, ²KyungHee University College of Medicine, Seoul, REPUBLIC OF KOREA, ³Yonsei University Wonju College of Medicine, Wonju, REPUBLIC OF KOREA.

766   Severe Peripheral Eosinophilia and Failure to Thrive with Complete Resolution of Symptoms with Milk Elmination

H. Ahluwalia, L. Bernstein, J. Shliozberg; Albert Einstein The Children's Hospital at Montefiore, Bronx, NY.

767   Clinical And Laboratorial Findings From Ige Mediated Cow's Milk Allergy (CMA) In Brazilian Pediatric Patients

A. K. F. Gushken, D. L. A. Pitarello, G. H. Yonamine, E. Ciccone, A. C. Brandão, A. P. B. M. Castro, A. C. Pastorino, C. M. A. Jacob; Depto. of Pediatrics, São Paulo, BRAZIL.

768   Isolated Food Pollen Syndrome in Response to Fresh Pineapple

E. S. Lavine ¹, A. R. Atkinson¹, A. K. Ellis²; ¹University of Toronto and Division of Immunology and Allergy, The Hospital for Sick Children, Toronto, ON, CANADA, ²Division of Clinical Immunology and Allergy, McMaster University, Hamilton, ON, CANADA.

769   Sensitization to Cannabis sativa in Tomato Sensitized Patients

C. Hernando de Larramendi ¹, J. García Abujeta¹, J. Carnés², E. Fernández-Caldas²; ¹Hospital Marina Baixa, Villajoyosa, SPAIN, ²Laboratorios LETI, SL, Tres Cantos, SPAIN.

770   Biological Standardization Of Hazelnut Extract In Selected Patients With Dbpcfc

F. Pineda; DIATER Laboratories, San Martin de la Vega, SPAIN.

771   Peanut Allergy and Peanut-specific IgG4 characteristics among Xhosa Children in Cape Town

G. Du Toit ¹, M. Levin², C. Motala², M. Perkin³, A. Stephens⁴, V. Turcanu⁴, G. Lack¹; ¹Children's Allergy Service. Evelina Children's Hospital, Guy's & St Thomas' NHS Foundation Trust, Kings College London, UNITED KINGDOM, ²Red Cross Children's Hospital, University of Cape Town, SOUTH AFRICA, ³Division of Community Health Sciences, St George's Hospital Medical School, UNITED KINGDOM, ⁴Kings College London, London, UNITED KINGDOM.

772   Angioedema Due to Blueberry Hypersensitivity

M. P. Wolbert, J. Baldwin; University of Michigan, Ann Arbor, MI.

773   Responses of Treatment Primary Eosinophilic Gastrointestinal Disorders with Corticosteroid, Montelukast and Ketotifen, 3 Cases Report

S. Nanthapisal, N. Vithayasai, T. Dangsuwan, S. Jennuwat, J. Sirikul, G. Pongsamat, M. Vangveeravong; Queen Sirikit National Institute of Child Health, Bangkok, THAILAND.

774   Atypical Presentation of Eosinophilic Gastroenteritis (EGE)

P. Kapur, B. Silverman, A. T. Schneider; Long Island College Hospital, Brooklyn, NY.

775   Eosinophilic Esophagogastritis In A Child With Atopy And Abdominal Pain

J. L. Caicedo, R. A. Caicedo; Wake Forest University, Winston-Salem, NC.

776   Anti-Allergic Effects of the Traditional Chinese Medicine Herbal Formula FAHF2 are Partially Dependent on Interferon-γ Activity

K. D. Srivastava, H. A. Sampson, X. Li; The Mount Sinai School of Medicine, New York, NY.

777   Severe Eosinophilia in a Pediatric Patient Following Hemolytic-Uremic Syndrome

G. C. Pien, T. Brown-Whitehorn; Children's Hospital of Philadelphia, Philadelphia, PA.

778   Total Serum Level Of Ige, Allergen-specific Ige And Blood Eosinophils In Food Allergy

J. T. Kim ¹, H. Kim¹, J. Yoon², J. Lee², S. Kim³; ¹Catholic University of Korea, Kyunggi-Do, REPUBLIC OF KOREA, ²Catholic University of Korea, Seoul, REPUBLIC OF KOREA, ³Pusan St.Mary's Hospital, Pusan, REPUBLIC OF KOREA.

Poster Session

4207

Monday, February 26, 2007

9:45 AM - 10:45 AM

Urticaria and Other Immunologic Skin Disorders

779   A Case of Hemolytic Anemia Following Intravenous Immuno-globulin Administration in a Patient With Chronic Urticaria

S. M. Herman ¹, S. Betschel², G. Sussman²; ¹McMaster University, Hamilton, ON, CANADA, ²University of Toronto, Toronto, ON, CANADA.

780   Localized Heat Induced Urticaria: A Case Report

C. O. Barnes, A. Kulczycki; Washington University, St. Louis, MO.

781   Chronic Idiopathic Urticaria May Not Be Idiopathic

M. E. Masching-Wright; Sneeze, Wheeze, and Itch Associates, Normal, IL.

782   Hydroxychloroquine in the Treatment of 12 Patients With Severe Chronic Idiopathic Urticaria; A Case Series

A. M. Ditto; Northwestern University Feinberg School of Medicine, Chicago, IL.

783   Evaluation of a Functional Assay for the Diagnosis of Autoimmune Chronic Urticaria (CU)

M. L. Altrich ¹, J. F. Halsey¹, L. C. Altman²; ¹IBT Reference Laboratory, Lenexa, KS, ²Dept Medicine University of Washington and Northwest Asthma and Allergy Center, Seattle, WA.

784   Serological Factors in Chronic Idiopathic Urticaria (CIU) in Relation To Disease Activity Over Time

J. A. Eckman, L. M. Gober, P. M. Sterba, R. G. Hamilton, S. S. Saini; Johns Hopkins Asthma and Allergy Center, Baltimore, MD.

785   Association of Chronic Idiopahic Urticaria with Autoimmunity and IgE levels

A. Chomiciene ¹, L. M. DuBuske², A. Blaziene¹; ¹Vilnius University, Vilnus, LITHUANIA, ²Immunology Research Institute of New England, Gardner, MA.

786   Investigation Of Complement Activation In Patients with Chronic Idiopathic Urticaria

S. N. Sharif, B. Goldberg; Kaiser Permanente Los Angeles, Los Angeles, CA.

787   Colchicine Use in Resistant Urticaria and Angioedema Patients: A Case Series

B. A. Martinez, I. C. Hanson, C. M. Davis; Baylor College of Medicine, Houston, TX.

788   Eosinophilic Fasciitis Masquerading as Angioedema

A. M. Dowden ^1,2, Z. K. Ballas^1,2; ¹University of Iowa, Iowa City, IA, ²Veterans Affairs Medical Center, Iowa City, IA.

789   Generalized Urticaria Due to Nickel Sensitivity

J. K. Lemmon, A. P. Knutsen, R. G. Slavin; St. Louis University School of Medicine, Saint Louis, MO.

790   Lymphocyte Response Pattern of Eczema Herpeticum Patients to Herpes Simplex Virus Antigen

H. C. Rerinck, S. Kamann, A. Wollenberg; Ludwig-Maximilian University, Munich, GERMANY.

791   A Murine Model of Eczema Vaccinatum

A. Elkhal ¹, J. Scott¹, D. H. MacArthur¹, R. He¹, M. D. Howell², E. Freyschmidt¹, H. C. Oettgen¹, D. Y. M. Leung², R. S. Geha¹; ¹Childrens Hospital Boston, Boston, MA, ²National Jewish Medical and Research center, Denver, CO.

792   Re Vaccination of Children with a History of an Allergic Reaction to a Vaccine After a Negative Intradermal Skin Test

M. Primeau, A. Des Roches; Sainte-Justine Hospital, University of Montreal, Montreal, PQ, CANADA.

793   Effects of Olopatadine on the Recovery of Skin Barrier Function and Epidermal Hyperplasia Induced by Skin Barrier Disruption in Mice

T. Amano, T. Takeda, H. Yano, T. Tamura; Kyowa Hakko Kogyo Co., Ltd., Shizuoka, JAPAN.

794   Olopatadine Ameliorates Rat Experimental Cutaneous Inflammation by Improving the Skin Barrier Function

T. Tamura, T. Amano, M. Chida, H. Yano; Kyowa Hakko Kogyo Co., Ltd., Shizuoka, JAPAN.

795   IL-13 Receptors in Cutaneous Inflammation

M. R. Warrier, A. Gibson, Y. Tabata, M. O. Daines, W. Chen, H. S. Akei, M. E. Rothenberg, G. K. Khurana Hershey; Cincinnati Children's Hosp. Med. Center, Cincinnati, OH.

796   Overexpression of Interleukin 13 (IL-13) in the Skin Induces Dermatitis and Pulmonary Inflammation and Airway Hyperresponsiveness to Allergen Challenge

T. Zheng, S. Oh, M. Oh, M. Wang, A. Myers, J. Schroeder, Z. Zhu; Johns Hopkins University, Division of Allergy & Clinical Immunology, Baltimore, MD.

797   Eyelid Dermatitis Due To Contact Allergy To Cocamidopropyl Betaine

H. D. Oei; Albert Schweitzer Hospital, Dordrecht, THE NETHERLANDS.

798   Contact Dermatitis To Atropine

C. A. Villanueva Alvarez-Santullano, V. Tovar Flores, P. Tornero Molina, M. De Barrio Fernandez, M. Baeza Ocho de Ocariz, S. Perez Bustamante, A. Prieto Garcia; HospitaL Universitario Gregorio Marañon, Madrid, SPAIN.

799   Perception of Factors Restricting Widely Performing Allergy Patch Testing: Comparison Between Allergists and Allergy Program Directors

G. Ghaffari, T. Craig; Penn State Milton S Hershey Medical Center, Hershey, PA.

800   Mast cell tryptase generate C3a from keratinocyte derived C3: Implication for allergic skin inflammation

R. Purwar ¹, M. Wittmann¹, J. Zwirner², M. Oppermann², M. Kracht¹, O. Dittrich-Breiholz¹, R. Gutzmer¹, T. Werfel¹; ¹Hannover Medical School, Hannover, GERMANY, ²Georg-August-University, Göttingen, GERMANY.

801   Serum IgE Concentrations in Bullous Pemphigoid Correlate with Disease Activity

L. A. Kelly, R. Holubkov, M. A. Campbell, K. S. Herlevi, T. Taylor, C. Hull, G. J. Gleich, J. J. Zone, K. M. Leiferman; University of Utah, Salt Lake City, UT.

802   Study of the Effect of the Antihistamine Agent Fexofenadine on Pruritus Associated with Asteatotic Dermatitis in the Elderly

T. Yudate; Sakai Hospital Kinki University School of Medicine, Sakai, JAPAN.

803   Combination Therapy with Dapsone, Colchine and Hydroxychloroquine in the Treatment of Urticarial Vasculitis

J. Melamed ¹, H. Laznickova²; ¹Allergy and Asthma Specialists, Chelmsford, MA, ²Allergy and Asthma Clinic P.C., Lexington, MA.

804   Cutaneous Leukocytoclastic Vasculitis in a Patient with HIV

S. A. Hodes, M. Carlson; University of California, Los Angeles, Los Angeles, CA.

805   Tamoxifen, A Possible Novel Therapy For Systemic Mastocytosis

R. Mian, P. E. Korenblat; Washington University School of Medicine, Barnes Jewish Hospital, St Louis, MO.

806   Urticaria: Characterization of 375 cases

M. D. C. Petrola ¹, P. Adriana¹, F. Maria¹, T. Alcira², Q. Velmar²; ¹University of Carabobo, Valencia, VENEZUELA, ²Ciudad Hospitalaria Enrique Tejera, Valencia, VENEZUELA.

807   The use of Danazol in the Management of Refractory Chronic Urticaria

M. Karakelides, C. R. Weiler; Mayo School of Graduate Medical Education, Rochester, MN.

808   A Case of Urticarial Vasculitis Associated with Chronic Lymphocytic Leukemia

J. C. Moore, M. B. Fasano; University of Iowa Hospitals and Clinics, Iowa City, IA.

809   Urticaria And Angioedema Caused By Currant Sauce

A. Rodríguez, M. de Barrio, M. Vázquez, P. Rojas, T. Herrero, M. Baeza; Hospital General Universitario Gregorio Marañón, Madrid, SPAIN.

810   Chronic Urticaria and Non Specific rash from the Herbal Product “Airborne”

R. M. Harris, M. S. Johnson; Allergy & Asthma Associates, Beverly Hills, CA.

811   Urticaria - A Rare Presentation of Sulfite Allergy

L. Yao, R. J. Bloomberg; Generations Medical Center, Tempe, AZ.

812   Contact Dermatitis Following Occupational Exposure to the New U.S. Army Combat Uniform (ACU)

C. B. Soltis ¹, C. K. Dolan², M. R. Nelson¹, S. A. Norton³; ¹Walter Reed Army Medical Center, Washington, DC, ²National Naval Medical Center, Bethesda, MD, ³Uniformed Serviced University of the Health Sciences, Bethesda, MD.

813   Evaluation of a Moisturizing Cream Containing Sweet Almond Oil and Gyceryl Polymethacrylate in Patients with Chronic Inflammatory Skin Diseases

U. Amon, S. Erndt; PsoriSol-Center for Dermatology & Allergy, Hersbruck, GERMANY.

814   Successful Treatment of Systemic Mastocytosis Associated with AML-M2, t(8:21) in a Child Using MRC-based AML Chemotherapy along with Gemtuzumab

D. K. Jeong, K. Fauman, C. Ross, C. Akin, R. Mody; University of Michigan, Ann Arbor, MI.

815   Tacrolimus Hydrate Ointment Inhibits Skin Plasma Extravasation Induced by Topically Applied m-Xylene But Not Capsaicin in Rat

S. Morii ¹, F. Kondo², Y. Ikai², M. Miyake¹, M. Futamura³, K. Ito³, T. Sakamoto¹; ¹Nagoya University Graduate School of Medicine, Nagoya, JAPAN, ²Aichi Prefectural Institute of Public Health, Nagoya, JAPAN, ³Division of Allergology, Aichi Children's Health and Medical Center, Obu, JAPAN.

816   Churg-Strauss Syndrome with Colonic Vasculitis

J. Jeong ¹, K. You², S. Nahm¹, E. Kim³; ¹ILSAN PAIK HOSPITAL, Kyungki-do, REPUBLIC OF KOREA, ²Kun-Kuk University Hospital, Seoul, REPUBLIC OF KOREA, ³Dong-Kuk University Hospital, Kyungki-do, REPUBLIC OF KOREA.

Poster Session

4208

Monday, February 26, 2007

9:45 AM - 10:45 AM

Underserved and Asthma Treatment

817   Dyspnea and Obesity in African-American Females: Is It Really Asthma?

D. Waggoner, J. Stokes, F. A. Romero, T. B. Casale; Creighton University, Omaha, NE.

818   A Systematic Review of Randomized Control Trials Evaluating the Effectiveness of Interactive Computerized Asthma Patient Education Programs

K. L. Bussey-Smith ¹, R. D. Rossen^1,2; ¹Baylor College of Medicine, Houston, TX, ²Micheal E. DeBakey Veterans Affairs Medical Center, Houston, TX.

819   Factors Associated with Increased Passive Cigarette Smoke Exposure in Inner City Asthmatic Children

S. J. Khiani ¹, S. J. Sietsema¹, L. Curtis², L. K. Sharp³, C. Catrambone⁴, K. B. Weiss^2,5, J. J. Shannon⁶, J. N. Moy^7,1; ¹Section of Allergy and Immunology, Rush University Medical Center, Chicago, IL, ²Institute for Healthcare Studies, Northwestern University, Chicago, IL, ³Department of Medicine, University of Illinois, Chicago, IL, ⁴Rush University College of Nursing, Chicago, IL, ⁵Institute for Healthcare Studies, Hines VA, Chicago, IL, ⁶Divisions of Pulmonary and Critical Care Medicine, Stroger Hospital of Cook County, Chicago, IL, ⁷Department of Pediatrics, Stroger Hospital of Cook County, Chicago, IL.

820   Recruitment Strategies in Under-Served Populatons for a Web-based Asthma Education Study Integrated with Nurse Case Management

A. D. Pulvermacher ¹, K. Kelly-Shanovich¹, C. A. Sorkness², A. Bhattacharya³, D. H. Gustafson¹; ¹Center for Health Enhancement Systems Studies, University of Wisconsin - Madison, Madison, WI, ²Schools of Pharmacy and Medicine, University of Wisconsin - Madison, Madison, WI, ³Center for the Study of Cultural Diversity in Healthcare, University of Wisconsin - Madison, Madison, WI.

821   Effects of Mepolizumab, an Anti-Interleukin-5 Monoclonal Antibody, on Blood Eosinophil Counts in Patients With Hypereosinophilic Syndrome

P. F. Weller ¹, G. J. Gleich², W. W. Busse³, M. E. Rothenberg, on behalf of the Mepolizumab HES Study⁴; ¹Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, ²Department of Dermatology, University of Utah School of Medicine, Salt Lake City, UT, ³Department of Medicine, University of Wisconsin Medical School, Madison, WI, ⁴Division of Allergy and Immunology, Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Poster Session

4209

Monday, February 26, 2007

9:45 AM - 10:45 AM

IgE and FceRI

822   The Allergic Profile Of Infants In The SAM Study: A Large Longitudinal Study Of Development Of Asthma And Allergies In Patients With Atopic Dermatitis

M. Boguniewicz ¹, L. Schneider², D. Leung¹, T. Hultsch³, J. Spergel⁴; ¹National Jewish Medical and Research Center, Denver, CO, ²Children's Hospital Boston, Boston, MA, ³Novartis Pharmaceuticals Corp, East Hanover, NJ, ⁴Children's Hospital of Philadelphia, Philadelphia, PA.

823   Cross-linking of FcɛRI on Dendritic Cells Skews CD4⁺ T cells towards a TH17 Phenotype

D. S. Cheung, M. M. Rohlfing, R. T. Kitchens, M. J. Holtzman, M. H. Grayson; Washington University School of Medicine, Saint Louis, MO.

824   Identifying the Presence and Function of the FcɛR1 Receptor in Human Normal and Small Airway Epithelium

E. Hochstadter ¹, J. Guay¹, B. Tolloczko¹, A. Soussi-Gounni², B. D. Mazer¹; ¹Meakins Christie Laboratories, Montreal, PQ, CANADA, ²University of Manitoba, Winnipeg, MB, CANADA.

825   Identification of Novel Candidate Gene/s Linked to Total Serum IgE Levels: An Integrative Genomic Approach

J. Batra, M. Sharma, R. Nagarkatti, B. Ghosh; Institute of Genomics and Integrative Biology, Delhi, INDIA.

826   Involvement of the High-affinity IgE Receptor (FCER1B) Gene Polymorphisms in the Susceptibility for Childhood Asthma

E. Kim ¹, K. Kim¹, J. Park¹, J. Hong¹, G. Jang², M. Sohn¹, K. Kim¹; ¹Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA, ²National Health Insurance Corporation Ilsan Hospital, Seoul, REPUBLIC OF KOREA.

827   The Prevalence of IgE Antibodies to Ascaris in Asthmatic Patients Living in a Tropical Environment

L. Caraballo ¹, D. Mercado¹, C. Vergara¹, A. Fernández², M. Gutiérrez²; ¹Institute for Immunological Research, University of Cartagena, Cartagena, COLOMBIA, ²Departamento de Microbiología y Parasitología, Universidad Nacional Autónoma de México, México, MEXICO.

828   Role Of Inhibitory Antibodies For The Prevention Of IgE-allergen Complex Formation/CD-23 Antigen Uptake: Impact Of Antibody Affinity And Clonality Using Defined Ratios Of Recombinant IgE, IgG And Der p 2

J. Holm, L. H. Christensen, J. Skovsgaard, P. A. Wurtzen, K. Lund; ALK-Abelló A/S, Hørsholm, DENMARK.

829   Total and Allergen Specific IgE Antibody Levels During and After Pregnancy in Relation to Maternal Allergic Disease

M. Sandberg, A. Frykman, M. Persson, J. Ernerudh, G. Berg, L. Matthiesen, C. Ekerfelt, M. C. Jenmalm; Linköping University, Linköping, SWEDEN.

830   IgE-dependent Activation Of Human Mast Cells Up-regulates FLIP And Mcl-1 Anti-apoptotic Proteins

B. Berent-Maoz, F. Levi-Schaffer; The Hebrew University of Jerusalem, Jerusalem, ISRAEL.

831   Specific IgE Response to Mites and Phenotypes of Allergic Disease in Childhood

M. I. Kidon ^1,2, S. Steinberg¹, L. Y. S. Tiong³, T. C. Ong³, H. S. Shang³, F. T. Chew³; ¹Children's Health Center, Rishon Lezion, ISRAEL, ²KK Children's Hospital, Singapore, SINGAPORE, ³Department of Biological Sciences, National University, Singapore, SINGAPORE.

832   Omalizumab Therapy in Evolving Allergic Bronchopulmonary Aspergillosis

S. Dave ¹, W. B. Cherry¹, D. E. Maddox²; ¹Mayo School of Graduate Medical Education, Rochester, MN, ²Mayo Clinic College of Medicine, Rochester, MN.

833   Efficacy of Omalizumab Using Extended Dose Intervals

R. M. Katz, A. W. Rafi, L. Do, M. Lin, R. Mangat, N. Azad, S. Sender; Allergy Asthma Care Center/UCLA, Santa Monica, CA.

834   Development Of A Monoclonal Antibody That Binds To Der P I Precursor And Blocks Serum Specific Ige Binding To Mite Allergen

W. Dai ^1,1, C. Shieh², J. Wang³; ¹Institude of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, TAIWAN, ²Institude of Microbilogy&Immunology, College of Medicine, National Cheng Kung University, Tainan, TAIWAN, ³Department of Pediatrics, College of Medicine, National Cheng Kung University, Tainan, TAIWAN.

835   A Systems Theory of Optimality in the Behavior of a Mast Cell

I. Bachelet ¹, A. Munitz¹, N. Linnenberg², Y. J. Pollak³, F. Levi-Schaffer¹; ¹The Hebrew University of Jerusalem, Jerusalem, ISRAEL, ²Freescale, Herzliya Pituach, ISRAEL, ³Mobileye Vision Technologies, Jerusalem, ISRAEL.

836   Regulation of Human Mast Cells by Fluticasone and Salmeterol

L. E. Erdos, R. P. Schleimer, M. Kulka; Northwestern University, Chicago, IL.

837   Effects of the Chinese Herbal Formula CUF2 on Cytokine Release from Human Mast Cell Line

Y. O. Wong, R. Y. T. Sung, K. Li, Y. Zhao, A. M. C. Li, K. P. Fung; The Chinese University of Hong Kong, Hong Kong, HONG KONG.

838   Pharmacological Cell and Tissue Models of Human Mast Cells for Compound Prioritization in Drug Development

C. Prothmann; ALTANA Research Institute, Waltham, MA.

839   Distinct Role Of Il-3 Promoter And Enhancer Region In Murine Mast Cells

A. Park; Chonnam National university, Gwangju, REPUBLIC OF KOREA.

840   Role of Mast Cell Mediators in Basal Cell Carcinoma

S. Z. Salim, F. A. Sorour, E. B. Abdelal, H. M. Hussein, E. E. Fouda; Al-Azhar Allergy & immunology Centre, Cairo, EGYPT.

841   Modulation of Histamine Release (HR) from Peripheral Blood Leukocytes (PBL) by Antioxidants

V. Windhorst, C. Bauer, B. Przybilla; Ludwig-Maximilians-Universität, Munich, GERMANY.

842   Ratio of IgE Receptor to TLR9 on Human Plasmacytoid Dendritic Cells Predicts Allergic Status and Cytokine Response to Innate and Adaptive Immune Stimuli

J. R. Tversky, A. P. Bieneman, K. L. Chichester, J. T. Schroeder; Johns Hopkins University, Baltimore, MD.

843   Circulating IgE and IgG Antigalectin - 1 Antibodies Associated with Asthma

J. Muino ¹, C. C. Castro¹, M. A. Sanabria¹, M. D. Romero², M. Ferrero², G. A. Rabinovich³; ¹Fac Cs MED - Universidad Nacional de Córdoba, Cordoba, ARGENTINA, ²LIIDO, Cordoba, ARGENTINA, ³Instituto de Inmunogenética - Facultad de Medicina Universidad Nacional de Buenos Aires, Buenos Aires, ARGENTINA.

Poster Session

4210

Monday, February 26, 2007

9:45 AM - 10:45 AM

Eosinophils I

844   IL-5 and the FIP1L1/PDGFRA Fusion Gene Cooperatively Promote Eosinophil Development, Activation, and Signal Transduction

Y. YAMADA ¹, J. A. Cancelas^2,3, D. A. Williams², M. E. Rothenberg¹; ¹Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Division of Experimental Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Hoxworth Blood Center, University of Cincinnati, Cincinnati, OH.

845   Pyk2 Signaling Events Mediate Eosinophil Chemotaxis Along Chemoattractant Gradients In The Lung

C. A. Lipinski ¹, R. Schubert¹, Z. Yang¹, R. S. Pero¹, M. Russ², S. Muller², H. Kohler³, J. J. Lee¹; ¹Mayo Clinic Arizona, Scottsdale, AZ, ²ImmPheron, Lexington, KY, ³InNexus Biotechnology, Scottsdale, AZ.

846   Kinetics of Cord Blood Eosinophil Lineage Biomarker mRNA: Co-expression of CysLTR1 with GATA-1

L. Crawford, A. K. Ellis, J. A. Denburg; McMaster University, Hamilton, ON, CANADA.

847   Cockroach Activates and Induces Degranulation of Human Eosinophils Through Protease-Activated Receptor-2

K. Wada, Y. Matsuwaki, T. A. Bingemann, H. Kita; Mayo Clinic College of Medicine, Rochester, MN.

848   Inhaled Budesonide At Low to Moderate Doses Is An Effective Treatment For Children With Eosinophilic Esophagitis

K. M. Maples, M. Graham, A. Irani; Virginia Commonwealth University, Richmond, VA.

849   Does Cigarette Smoke Modify Eosinophil Properties? Implications for Chronic Lung Disease

L. H. Bellehsen; Hebrew University of Jerusalem, Jerusalem, ISRAEL.

850   A Novel Method to Detect and Quantitate Pulmonary Eosinophils

W. W. Stevens ^1,2, T. S. Kim¹, L. M. Pujanauski^1,3, T. J. Braciale^1,4; ¹Beirne Carter Center for Immunology Research, University of Virginia Health Sciences Center, Charlottesville, VA, ²Department of Microbiology, University of Virginia Health Sciences Center, Charlottesville, VA, ³Department of Biology, University of Virginia, Charlottesville, VA, ⁴Departments of Pathology and Microbiology, University of Virginia Health Sciences Center, Charlottesville, VA.

851   IP-10 Augments Eosinophil Adhesion To ICAM-1

T. Kobayashi, T. Soma, Y. Takaku, K. Hagiwara, M. Kanazawa, M. Nagata; Saitama Medical University, Saitama-ken, JAPAN.

852   Interferon-γ Enhances Human Eosinophil Effector Functions Induced by Th2-type Cytokines

M. Kato ^1,2, T. Yamaguchi¹, K. Kozawa¹, H. Kimura³; ¹Gunma Prefectural Institute of Public Health and Environmental Sciences, Maebashi, Gunma, JAPAN, ²Gunma Children's Medical Center, Shibukawa, Gunma, JAPAN, ³National Institute of Infectious Disease, Tokyo, JAPAN.

853   Eosinophils Respond to Acidic environments with cAMP Generation in a TDAG8-Dependent Manner

L. C. Kottyan ¹, A. R. Collier¹, K. A. Niese¹, C. O. Radu², O. N. Witte², M. E. Rothenberg¹, N. Zimmermann¹; ¹Cincinnati Children's Hospital, Cincinnati, OH, ²University of California Los Angeles, Los Angeles, CA.

854   Inhibition of Eosinophil Survival by Peroxisome Proliferator-Activated Receptor (PPAR) alpha Agonists

T. Adachi ¹, S. Ueki¹, H. Nagase¹, J. Chihara², K. Ohta¹; ¹Teikyo University School Medicine, Tokyo, JAPAN, ²Akita University School Medicine, Akita, JAPAN.

855   L-plastin Interacts with Receptor for Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Transduces Antiapoptotic Signaling in Human Eosinophils

T. W. Young, K. Pazdrak, C. Straub, S. Stafford, A. Kurosky; University of Texas Medical Branch, Galveston, TX.

856   Human Airway Eosinophils Exhibit Differential Regulation of ERK and STAT5-Associated Signaling Responses to Interleukin-5 (IL-5) and Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF)

C. J. Koziol, M. Bates, P. J. Bertics; University of Wisconsin-Madison, Madison, WI.

857   Inhibitor of Apoptosis Proteins in the Regulation of Eosinophil Apoptosis in Allergic Disease

V. Mehta ¹, B. Moore², A. Bewtra¹, D. K. Agrawal²; ¹Center for Allergy, Asthma and Immunology, Creighton University, Omaha, NE, ²Department of Biomedical Sciences, Creighton University, Omaha, NE.

858   Molecular Markers of Eosinophilopoiesis: Multiplex Q-PCR Analysis of GATA-1, MBP and IL-5 Receptor mRNA Expression in Peripheral Blood

A. K. Ellis, L. Crawford, J. A. Denburg; McMaster University, Hamilton, ON, CANADA.

859   A3 Adenosine Receptors Modulate Eosinophil Function In Bleomycin-Induced Lung Injury

E. Morschl ¹, J. B. Volmer¹, J. G. Molina¹, J. J. Lee², S. I. Ochkur², M. R. Blackburn¹; ¹The Medical School at the University of Texas Houston, Houston, TX, ²Mayo Clinic Scottsdale, Scottsdale, AZ.

860   Expression and Activation of Toll Receptor 7 (TLR7) In Human Eosinophils: Effect on Eosinophil Survival and Cytokine Production

K. Pazdrak, C. Straub, V. Starosta, S. Stafford, T. W. Young, A. Kurosky; University of Texas Medical Branch, Galveston, TX.

861   Differential Effects of Adhesion Molecules on Eosinophil Superoxide Anion Generation Induced by Leukotriene D4

M. Nagata, M. Kushiya, T. Kobayashi, K. Hagiwara, M. Kanazawa; Saitama Medical University, Saitama, JAPAN.

862   TGF-beta Regulation Of Bone Marrow Eosinophil Production

M. Hogan, D. Piktel, L. F. Gibson, K. S. Landreth; West Virginia University, Morgantown, WV.

863   Rapid Selective Priming Of FcαR On Eosinophils By Corticosteroids

M. Bracke ^1,2, W. ten Hove^1,2, L. A. Houben², J. A. M. Raaijmakers¹, L. Koenderman²; ¹Utrecht Institute for Pharmaceutical Sciences, Utrecht, THE NETHERLANDS, ²Dept. Pulmonary Diseases, University Medical Center, Utrecht, THE NETHERLANDS.

864   Nonspecific Bronchial Hyperresponsiveness Caused by T. canis 2nd Stage Larval Infestation

S. Lee ¹, S. Kyung¹, C. An¹, S. Jeong¹, Y. Kim¹, M. Kim¹, K. Ha², D. Choi³, S. Kang⁴, Y. Chung⁵; ¹Gachon University of medicine and science, Incheon, REPUBLIC OF KOREA, ²Sung Ae General Hospital, Seoul, REPUBLIC OF KOREA, ³Samsung Medical Center, Seoul, REPUBLIC OF KOREA, ⁴Chung Ang University, Seoul, REPUBLIC OF KOREA, ⁵Jeju National University, Jeju, REPUBLIC OF KOREA.

865   Age-related Changes in Eosinophil Function in Asthma Subjects

S. K. Mathur, E. A. Schwantes, R. L. Brandau; University of Wisconsin, Madison, WI.

866   Retinoic Acids Induce Eosinophil Survival and MCP-1 Production

S. Ueki ¹, G. Mahemuti², W. Ito², Y. Kobayashi², T. Chiba², H. Oyamada², Y. Kamada², K. Yamaguchi², M. Takeda², H. Kayaba², J. Chihara²; ¹Teikyo University School of Medicine, Tokyo, JAPAN, ²Akita University School of Medicine, Akita, JAPAN.

867   TGF-β1 Increases Chloride Channel Activity in and Migration of Human Blood Eosinophils via Intracellular Pathways involving Protein Kinase C

B. Moore ¹, G. Cheng¹, M. Kim¹, D. K. Agrawal^1,2; ¹Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, NE, ²Department of Internal Medicine, Creighton University School of Medicine, Omaha, NE.

868   Comparison Between Peripheral Blood and Nasal Polyp Eosinophils Reveals a Distinct Profile of Surface Receptors

A. H. Nissim Ben Efraim ¹, I. Bachelet¹, A. Munitz¹, R. Eliashar², F. Levi-Schaffer¹; ¹The Hebrew University of Jerusalem, Jerusalem, ISRAEL, ²The Hadassah Ein-Karem University Hospital, Jerusalem, ISRAEL.

869   Bovine Dural Graft: A Unique Cause of Unexplained Fever, Erythroderma and Eosinophilia

W. B. Cherry, M. F. Hartz, M. T. McEvoy, S. T. Pittock; Mayo Clinic, Rochester, MN.

870   A Comparison of Nasal Smear Eosinophil Count via Blow Technique vs the Nasal Scrape Method

M. Varghese, P. Lieberman; University of Tennessee, Memphis, TN.

871   Eosinophilic Leukemoid Reaction in a Woman with Spindle Cell Sarcoma of the Leg

C. B. Lauter ¹, M. Snyder¹, A. Armin², I. Jaiyesimi³, M. Kolins⁴, J. Burdakin³, K. Les⁵; ¹William Beaumont Hospital-Division of Allergy/Immunology, Royal Oak, MI, ²William Beaumont Hospital-Department of Anatomic Pathology, Royal Oak, MI, ³William Beaumont Hospital-Division Hematology/Oncology, Royal Oak, MI, ⁴William Beaumont Hospital-Department of Clinical Pathology, Royal Oak, MI, ⁵William Beaumont Hospital-Department of Orthopedic Surgery, Royal Oak, MI.

872   [Withdrawn]

873   The Effects of rhSCF on Human Eosinophil Chemokine Receptor Expression

R. W. Keeton, Jr., N. Lukacs; U. of Michigan, Ann Arbor, MI.

874   PEG-Interferon after Interferon alfa-2b for Hypereosinophilic Syndrome

J. Butterfield; Mayo Clinic, Rochester, MN.

875   Eosinophilia and Adrenal Insufficiency

C. C. Hassett, L. G. Wild; Tulane University, New Orleans, LA.

876   Reactive Eosinophilia to Invasive Candidiasis Responding to Caspofungin

G. Shanmugam, B. L. Buchmiller, D. A. Wierzbicki, M. T. de la Morena; UT Southwestern, Dallas, TX.

877   Churg-Strauss Presenting as Pulmonary Embolism, Lymphadenopathy and Eosinophilia

T. Chacko, R. Frank, D. Ledford, R. F. Lockey; University of South Florida Collge of Medicine, Tampa, FL.

Poster Session

4211

Monday, February 26, 2007

9:45 AM - 10:45 AM

Epidemiology of Rhinitis, Sinusitis and Allergic Ocular Disease

878   Allergens Associated with Ocular and Nasal Symptoms: An Epidemiologic Study

K. Singh, L. Bielory, E. Kavosh; UMDNJ, Newark, NJ.

879   Prevalence of Rhinitis among Children and Teenagers in Quito Ecuador

S. F. Barba, Jr.; Hospital General FF AA, Quito, ECUADOR.

880   High Prevalence of Sensitization to Japanese Cedar Pollen and House Dust Mite in Young Children in Japan

S. Masuda ^1,2, T. Fujisawa^1,2, M. Nambu^3,2, Y. Suehiro^4,2, A. Terada^5,2, Y. Tohda^6,2; ¹Mie National Hospital, Tsu, JAPAN, ²Kinki-Hokuriku Airway Disease Conference (KiHAC), Osaka, JAPAN, ³Tenri-Yorozu General Hospital, Tenri, JAPAN, ⁴Saiseikai Nakatsu Hospital, Osaka, JAPAN, ⁵Daido Hospital, Nagoya, JAPAN, ⁶Kinki University School of Medicine, Osaka, JAPAN.

881   Allergic Rhinitis and Immunoglobulin Deficiency in Preschool Children with Frequent Upper Respiratory Illness

S. Siriaksorn ¹, M. Trakultivakorn¹, S. Suchaitanawanit²; ¹Division of Allergy and Clinical Immunology, Department of Pediatrics, Faculty of medicine, Chiang Mai University, Chiang Mai, THAILAND, ²Section of Immunology, Central Laboratory, Faculty of Medicine, Chiang Mai University, Chiang Mai, THAILAND.

882   The Trends of Prevalence of Allergic Rhinitis among Elementary School Children in Seoul from 1995 to 2005: Stable but Increased Recognition

Y. Ahn; Eulji University School of Medicine, Seoul, REPUBLIC OF KOREA.

883   Firstborn Status, Early Day Care Use and Allergen-Specific IgE, Hay Fever, and Asthma in Young Adults

C. C. Johnson ¹, G. R. Wegienka¹, S. L. Havstad¹, K. J. Woodcroft¹, L. K. Williams¹, C. L. M. Joseph¹, D. R. Ownby², E. M. Zoratti³; ¹Dept of Biostatistics and Research Epidemiology, Henry Ford Hospital & Health System, Detroit, MI, ²Medical College of Georgia, Augusta, GA, ³Section of Allergy & Clinical Immunology, Henry Ford Hospital & Health System, Detroit, MI.

884   Assessment Of A Rhinitis Questionnaire In A Seasonal Allergic Rhinitis Population

J. A. Bernstein ¹, D. Brandt¹, P. Ratner², W. Wheeler³; ¹University of Cincinnati, Cincinnati, OH, ²Sylvana Research Associates, San Antonio, TX, ³MedPointe Pharmaceuticals, Somerset, NJ.

885   Evaluation Of A Rhinitis Questionnaire In Different Regions Within The United States

D. Brandt ¹, A. El-Hag², C. Abbott³, J. A. Bernstein^1,3; ¹University of Cincinnati, Cincinnati, OH, ²Allergy and Immunology, Plano, TX, ³Bernstein Allergy Group, Cincinnati, OH.

886   The Burden Of Rhinitis In A Managed Care Organization (MCO)

R. Zeiger¹, M. Schatz ¹, W. Chen², S. Yang², M. Corrao³, V. Quinn²; ¹Kaiser Permanente, San Diego, CA, ²Kaiser Permanente, Los Angeles, CA, ³GlaxoSmithKline, Research Triangle Park, NC.

887   Symptom Burden During the Winter for Allergic and Non-allergic Rhinitis Sufferers

R. Nathan¹, E. Meltzer², J. Derebery³, P. Stang⁴, U. Campbell⁴, M. Corrao⁵, R. Stanford ⁵; ¹Asthma & Allergy Associates, Colorado Springs, CO, ²Allergy and Asthma Medical Group and Research Center, San Diego, CA, ³House Ear Clinic, Los Angeles, CA, ⁴Galt Associates, Blue Bell, PA, ⁵GlaxoSmithKline, Research Triangle Park, NC.

888   Allergies in Canada: AR Patient Perspectives on Prescription Nasal Sprays

M. Desrosiers ^1,2, P. Keith³, R. Schellenberg⁴, S. Waserman⁵; ¹McGill University, Montreal, PQ, CANADA, ²Université de Montréal, Montreal, PQ, CANADA, ³McMaster University, Hamilton, ON, CANADA, ⁴University of British Columbia, Vancouver, BC, CANADA, ⁵University of Toronto, Toronto, ON, CANADA.

889   Physicians' Perspectives of Allergic Rhinitis (AR) in Canada

R. Schellenberg ¹, P. Keith², M. Desrosiers³, S. Waserman²; ¹University of British Columbia, Vancouver, BC, CANADA, ²McMaster University, Hamilton, ON, CANADA, ³McGill University, Montreal, PQ, CANADA.

890   Subjective Effects of Allergic Rhinitis on Sleep Quality and Amount During the Winter

E. Meltzer¹, R. Nathan², J. Derebery³, P. Stang⁴, U. Campbell⁴, M. Corrao⁵, R. Stanford ⁵; ¹Allergy and Asthma Medical Group and Research Center, San Diego, CA, ²Asthma & Allergy Associates, Colorado Springs, CO, ³House Ear Clinic, Los Angeles, CA, ⁴Galt Associates, Blue Bell, PA, ⁵GlaxoSmithKline, Research Triangle Park, NC.

891   The Burden Of Non-Allergic Versus Allergic Rhinitis In A Managed Care Organization (MCO)

M. Schatz ¹, W. Chen², S. Yang², M. Corrao³, V. Quinn², R. Zeiger¹; ¹Kaiser Permanente, San Diego, CA, ²Kaiser Permanente, Los Angeles, CA, ³GlaxoSmithKline, Research Triangle Park, NC.

892   Evaluation and Control of Allergic Rhinitis in Patients with Asthma (CARINA) in Korea

Y. Rha ¹, B. Son²; ¹Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, College of Medicine, Inha University, Inchon, REPUBLIC OF KOREA.

893   Burden of Illness of Allergic Rhinitis in Canada

P. K. Keith ¹, M. Desrosiers², S. Waserman¹, R. R. Schellenberg³; ¹McMaster University, Hamilton, ON, CANADA, ²McGill University, Universite de Montreal, Montreal, PQ, CANADA, ³University of British Columbia, Vancouver, BC, CANADA.

894   Characterization of Chronic Rhinitis in Children

R. Kachru, J. Friedrich, J. Corren; Allergy Research Foundation, Los Angeles, CA.

895   Clinical Characteristics of Allergic Rhinitis and Nonallergic Rhinitis in Pediatric Allergy Clinic at Siriraj Hospital, Thailand

C. Suratannon, P. Lertbunnaphong, O. Jirapongsananuruk, N. Visitsunthorn, P. Vichyanond; Siriraj Hospital, Bangkok, THAILAND.

896   Nasal Spray Device And Formulation Attributes May Contribute To Stopping Treatment With Prescription Nasal Sprays

R. Stanford ¹, E. Meltzer², R. Nathan³, J. Derebery⁴, P. Stang⁵, U. Campbell⁵; ¹GlaxoSmithKline, Research Triangle Park, NC, ²Allergy and Asthma Medical Group and Research Center, San Diego, CA, ³Asthma & Allergy Associates and Research Center, Colorado Springs, CO, ⁴House Ear Clinic, Los Angeles, CA, ⁵Galt Associates, Blue Bell, PA.

897   US and European Perspective on the Burden of Chronic Sinusitis: Survey of Allergists and Otolaryngologists

L. Katz ¹, R. Casciano¹, A. Stergious¹, M. Memran², J. Willet¹; ¹Accentia Biopharmaceuticals, New York City, NY, ²Analytica International, New York City, NY.

Poster Session

4212

Monday, February 26, 2007

9:45 AM - 10:45 AM

Therapy of Allergic Conjunctivitis and Allergic and Non-Allergic Rhinitis

898   Efficacy and Safety of Mometasone Furoate Alone or With Concomitant Medication for Perennial and Seasonal Allergic Rhinitis

H. Ulmer; Medizinische Universität Innsbruck, Innsbruck, AUSTRIA.

899   A Real World Open-label Multicenter Single Group Study to Evaluate Patients' Reactions to Mucinex

(Single Entity Long-acting Guaifenesin)

W. W. Storms ¹, M. A. Kaliner², M. Javidi³, J. R. Farrar⁴, C. S. Efessiou⁵; ¹The Williams Storms Allergy Clinic, Colorado Springs, CO, ²The Institute for Asthma and Allergy, Wheaton and Chevy Chase, MD, ³North Carolina State University, Raleigh, NC, ⁴SRxA Institute for Professional Education, Washington, DC, ⁵Strategic Pharmaceutical Advisors, Inc., Washington, DC.

900   Patient Comparison of Sensory Attributes of Olopatadine and Azelastine Nasal Sprays

E. O. Meltzer ¹, W. E. Berger², S. J. Chadwick³, G. Gross⁴, C. F. LaForce⁵, R. Garadi⁶, K. Crenshaw⁶, G. M. Wall⁶; ¹Allergy & Asthma Medical Group & Research Center, San Diego, CA, ²Allergy & Asthma Associates of Southern California, Mission Viejo, CA, ³ENTA Allergy, Head & Neck Institute, Decatur, IL, ⁴Pharmaceutical Research and Consulting, Inc., Dallas, TX, ⁵North Carolina Clinical Research, Raleigh, NC, ⁶Alcon Research, Ltd., Fort Worth, TX.

901   Acoustic Rhinometry And Symptoms Score Evaluation During The Treatment With Desloratadine In Pediatric Patients With Allergic Rhinitis

A. B. F. Fomin, A. G. A. Oliveira, A. C. Pastorino, C. M. A. Jacob; Faculty of Medicine of University of Sao Paulo, Sao Paulo, BRAZIL.

902   Fluticasone Furoate^∗ (FF) Nasal Spray-Ergonomic Considerations for a Next Generation Delivery System

[^∗USAN approved name]

J. W. Godfrey, A. C. Grant, A. L. Slater; GlaxoSmithKline Research & Development, Ware, Hertfordshire, UNITED KINGDOM.

903   Once-Daily Fluticasone Furoate^∗ Nasal Spray (FFNS) Improves Quality of Life (QoL) in Subjects with Seasonal Allergic Rhinitis (SAR) during the mountain cedar pollen season

^∗USAN approved name

J. H. van Bavel ¹, T. Toler², A. Ellsworth², R. Stanford², E. Philpot²; ¹Allergy & Asthma Associates Research Dept., Austin, TX, ²GlaxoSmithkline, RTP, NC.

904   Do Allergic Rhinitis (AR) Patients Achieve Twenty-four Hour Symptom Control?

A. Dalal ¹, A. E. Williams², S. Kay³; ¹GlaxoSmithKline, Research Triangle Park, NC, ²GlaxoSmithKline R&D, London, UNITED KINGDOM, ³Adelphi Group Products, Macclesfield, UNITED KINGDOM.

905   Buffered Hypertonic Saline Nasal Spray and Gel As Treatment Modifiers in Allergic and Vasomotor Rhinitis

J. N. Hausfeld; George Washington University School of Medicine and Health Sciences, Washington, DC.

906   Ocular Efficacy of a Novel, Enhanced Affinity Corticosteroid, Fluticasone Furoate^∗ Nasal Spray, in Ragweed-Sensitive Patients

^∗USAN-approved name

W. R. Lumry ¹, S. H. Cohen², A. Levy³, E. Philpot⁴, T. Toler⁴, A. Ellsworth⁴; ¹Allergy and Asthma Specialists, Dallas, TX, ²Allergic Diseases, Milwaukee, WI, ³Foot Hills Asthma & Allergy Association, Spartanburg, SC, ⁴GlaxoSmithKline, Research Triangle Park, NC.

907   Fluticasone Furoate^∗ (FF) Nasal Spray - Development of a Next-Generation Delivery System for Allergic Rhinitis

[^∗USAN approved name]

W. Berger ¹, J. W. Godfrey², A. C. Grant², A. L. Slater², S. J. Broughton²; ¹Southern California Research, Mission Viejo, CA, ²GlaxoSmithKline Research & Development, Ware, Hertfordshire, UNITED KINGDOM.

908   Once-daily Fluticasone Furoate^∗ Nasal Spray (FF) Effectively Treats Ocular Symptoms Of Seasonal Allergic Rhinitis (SAR) Caused By Mountain Cedar Pollen

^∗USAN Approved Name

P. Ratner ¹, C. Andrews², J. van Bavel³, T. Toler⁴, A. Ellsworth⁴, E. Philpot⁴; ¹Sylvana Research Associates, San Antonio, TX, ²Diagnostics Research Group, San Antonio, TX, ³Allergy and Asthma Associates, Austin, TX, ⁴GlaxoSmithKline, Research Triangle Park, NC.

909   Lack of Effect on Hypothalamic-Pituitary-Adrenal (HPA)Axis Function by Once-daily Fluticasone Furoate^∗ Nasal Spray (FFNS) 110 mcg in Children with Perennial Allergic Rhinitis (PAR)

^∗USAN approved name

I. Tripathy ¹, R. Sterling², D. Clements³, W. Wu³, M. Faris³, E. Philpot³; ¹Clinical Research of the Ozarks, Rolla, MO, ²Carolina Research, Orangeburg, SC, ³GlaxoSmithKline, Research Triangle Park, NC.

910   Once-daily Fluticasone Furoate^∗ Nasal Spray (FFNS) is Effective for the Treatment of Seasonal Allergic Rhinitis (SAR) Caused by Ragweed

^∗USAN-approved name

H. B. Kaiser ¹, R. Naclerio², J. Given³, E. Philpot⁴, T. Toler⁴, A. Ellsworth⁴; ¹Asthma and Allergy Specialists, Minneapolis, MN, ²University of Chicago Hospitals, Chicago, IL, ³Allergy and Respiratory Center, Canton, OH, ⁴GlaxoSmithKline, Research Triangle Park, NC.

911   Rhinorrhea Not Responding to Nasal Corticosteroids

P. N. Patel ¹, B. Oyefara¹, R. Aarstad², S. L. Bahna¹; ¹Allergy/Immunology Section, Louisiana State University Health Sciences Center, Shreveport, LA, ²Otolaryngology Department, Louisiana State University Health Sciences Center, Shreveport, LA.

Oral Abstract Session

4601

Monday, February 26, 2007

1:45 PM - 3:00 PM

Antiviral Immunity

912   Viremia is Associated with Sleep Disturbances, Neurocognitive Disorders and Cytokine Dysregulation in Pediatric HIV Infection

S. B. Foster ¹, M. E. Paul¹, D. G. Glaze¹, J. M. Reuben², L. L. Harris¹, E. N. Cohen², B. Lee², C. A. Kozinetz¹, H. L. Schwarzwald¹, M. W. Kline¹, C. D. Jackson¹, A. J. Loeb¹, P. E. Frerking¹, J. E. Fehlis¹, P. Y. Brouwers¹, W. T. Shearer¹; ¹Baylor College of Medicine, Houston, TX, ²University of Texas, MD Anderson Cancer Center, Houston, TX.

913   Epigallocatechin Gallate Inhibits HIV-1-gp120-Induced Immune Dysregulation and Apoptosis in Human Lymphocytes

C. L. Nance ^1,2, S. P. Westerfield², V. C. Willis², W. T. Shearer^1,2; ¹Texas Children's Hospital, Houston, TX, ²Baylor College of Medicine, Houston, TX.

914   Characterization of Antigen Presenting Cells of Peripheral Blood in Patients with HCV infection During Immunotherapy

L. P. Titov ¹, U. V. Tarasiuk¹, I. A. Karpov², E. N. Yagovdik-Telezhnaya², L. M. DuBuske³; ¹Belarusian Research Institute for Epidemiology and Microbiology, Minsk, BELARUS, ²Belarusian State Medical University, Minsk, BELARUS, ³Immunology Research Institute of New England, Gardner, MA.

915   Characterization of Peripheral Blood Mononuclear Cells and Dendritic Cells in Patients with Viral Hepatitis C

L. Titov ¹, U. V. Tarasiuk¹, E. N. Yagovdik-Telezhnaya², I. A. Karpov², D. A. Charnashey², L. M. DuBuske³; ¹Belarusian Research Institute for Epidemiology and Microbiology, Minsk, BELARUS, ²Belarusian State Medical University, Minsk, BELARUS, ³Immunology Research Institute of New England, Gardner, MA.

916   Inhibition of Respiratory Syncytial Virus (RSV) Replication in Cell Culture by Small Interfering RNA (siRNA)

M. R. Khaitov ¹, V. S. Akimov¹, E. B. Faizuloev¹, A. A. Nikonova¹, L. P. Alexeev¹, V. V. Zverev¹, L. M. DuBuske²; ¹Institute of Immunology, Moscow, RUSSIAN FEDERATION, ²Immunology Research Institute of New England, Gardner, MA.

917   Diminished Airway Inflammation against Double-stranded RNA in Mast Cell-Deficient Mice

H. Nagase ¹, K. Noda¹, M. Yamaguchi², H. Yoshihara¹, K. Yamamura¹, T. Yano¹, S. Ueki¹, H. Ishida¹, O. Ohbayashi¹, M. Nakajima¹, T. Adachi¹, K. Ohta¹; ¹Teikyo University, Tokyo, JAPAN, ²University of Tokyo, Tokyo, JAPAN.

Oral Abstract Session

4602

Monday, February 26, 2007

1:45 PM - 3:00 PM

Molecular Mechanisms of Allergic and Immunologic Disease

918   Characterization of Bet v 1 Specific CD4+ T cell Responses in Allergic and Non Allergic Individuals

M. Philippe; Stallergenes SA, Antony, FRANCE.

919   Interleukin-5 Receptor Endocytosis is Regulated by Two Distinct Pathways

M. Moczygemba, J. T. Lei; Baylor College Of Medicine, Houston, TX.

920   G-Protein Receptor Kinases (grKs) Play an Important Regulatory Role in the K/BxN Serum Transfer Model of Inflammatory Arthritis

T. K. Tarrant ¹, R. R. Rampersad¹, C. G. Moore¹, L. R. Rothlein¹, R. M. Lefkowitz², D. M. Lee³, D. D. Patel⁴; ¹University of North Carolina, Chapel Hill, NC, ²Duke University, Durham, NC, ³Brigham and Women's Hospital, Boston, MA, ⁴Novartis, Basel, SWITZERLAND.

921   Flt3 Ligand (FL) Treatment Generates Multiple Subsets of Myeloid Dendritic Cells (DCs) with Differential Phenotypic and Functional Properties in Mouse Model of Asthma

A. S. Bharadwaj, D. K. Agrawal; Creighton University, Omaha, NE.

922   Thymic Stromal Lymphopoietin (TSLP) and Receptor (TSLPR) and CD11c⁺ Dendritic Cells (DC) in Allergen-induced Cutaneous Late Phase Responses (LPR) in Atopic Subjects

S. Ying ¹, Y. H. Wang², Y. J. Liu², Q. Meng¹, A. B. Kay³, S. Phipps³, T. H. Lee¹, C. J. Corrigan¹; ¹King's College London, London, UNITED KINGDOM, ²Centre of Cancer Immunolgy, MD Anderson Cancer Centre, Houston, TX, ³Imperial College, London, UNITED KINGDOM.

923   Atrial Natriuretic Peptide (ANP)-mediated Maturation and Cytokine Phenotype of Human Dendritic Cells (DCs) Involve Demethylation of the SOCS3 Promoter

W. Zhang, X. Cao, G. Hellermann, R. F. Lockey, S. S. Mohapatra; USF, Tampa, FL.

Oral Abstract Session

4603

Monday, February 26, 2007

1:45 PM - 3:00 PM

The Health Effects of Air Pollutants In and Out of the Workplace

924   Early Childhood Environmental Tobacco Smoke Exposure is Associated with Lower Serum Total IgE at 18 Years

K. J. Woodcroft ¹, S. Havstad¹, D. R. Ownby², C. C. Johnson¹, E. M. Zoratti¹; ¹Henry Ford Health System, Detroit, MI, ²Medical College of Georgia, Augusta, GA.

925   Children Demonstrate Diminished Antioxidant Defenses Against Diesel Exhaust Particles

E. M. Lin, L. Zhang, D. Diaz-Sanchez; University of California at Los Angeles, Los Angeles, CA.

926   Characterization of Diesel Exposure and Wheezing in Infants: the Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS)

P. H. Ryan ¹, G. K. LeMasters¹, P. Biswas², S. Hu², D. I. Bernstein¹, J. Lockey¹, M. Villareal¹, G. K. Khurana Hershey³, S. Grinshpun¹; ¹University of Cincinnati, Cincinnati, OH, ²Washington University, St. Louis, MO, ³Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

927   Th2 Cytokine Profiles Do Not Predict Antibody Responses and Respiratory Hyperresponsiveness Following Dermal Exposure To Isocyanates

M. J. K. Selgrade ¹, E. H. Boykin¹, N. Haykal-Coates¹, M. R. Woolhiser², C. Wiescinski², D. L. Andrews¹, A. K. Farraj¹, D. L. Doerfler¹, S. H. Gavett¹; ¹U.S. Environmental Protection Agency, Research Triangle Park, NC, ²The Dow Chemical Company, Midland, MI.

928   Occupational Latex Allergy in Non-Health Care Workers with Rubber Glove Exposure

R. Lleonart, M. Corominas; Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, SPAIN.

929   Beta 2-Adrenergic Receptor Gene 46 A>G Polymorphism May Confer Specific IgE Sensitization In Toluene Diisocyanate-Exposed Workers

Y. Ye ¹, H. Park¹, S. Kim¹, Y. Kang¹, C. Kim², H. Kim³, C. Hong⁴, A. Jang⁵, C. Park⁵, A. V. Wisnewski⁶, C. A. Redlich⁶; ¹Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA, ²Inha University College of Medicine, Incheon, REPUBLIC OF KOREA, ³The Catholic University of Korea, Seoul, REPUBLIC OF KOREA, ⁴Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA, ⁵Soonchunhyang University Hospital, Bucheon, REPUBLIC OF KOREA, ⁶Yale School of Medicine, New Heaven, CT.

Oral Abstract Session

4604

Monday, February 26, 2007

1:45 PM - 3:00 PM

Atopic Dermatitis

930   Probiotics in the Prevention of IgE-Associated Eczema: a Double Blind Randomised Placebo-Controlled Trial

T. Abrahamsson ¹, T. Jakobsson¹, M. Fagerås Böttcher¹, M. Fredrikson², M. C. Jenmalm¹, B. Björkstén³, G. Oldaeus⁴; ¹Department of Molecular and Clinical Medicine, Division of Pediatrics, Linköping, SWEDEN, ²Department of Molecular and Clinical Medicine, Division of Occupational and Environmental Medicine, Linköping University, Sweden, Linköping, SWEDEN, ³Institute of Environmental Medicine, Karolinska Institutet, Stockholm, SWEDEN, ⁴Department of Pediatrics, County Hospital Ryhov, Jönköping, SWEDEN.

931   Role of CD4⁺CD25high T Cells in the Persistence of Atopic Dermatitis

A. Singh, K. Burmeister, M. L. Jennes-Clough, R. Gangnon, M. Evans, K. A. Roberg, C. Tisler, D. DaSilva, T. Pappas, J. E. Gern, R. F. Lemanske, Jr., C. M. Seroogy; University of Wisconsin - Madison, Madison, WI.

932   GM-CSF Pathway Defects May Account for Reduced Neutrophil Chemotaxis in Atopic Dermatitis

L. G. Bankova ¹, M. E. Brummet², B. S. Bochner², D. N. Grigoryev², K. C. Barnes², L. A. Beck¹; ¹Department of Dermatology and Division of Allergy/Immunology & Rheumatology, University of Rochester School of Medicine & Dentistry, Rochester, NY, ²Division of Allergy & Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD.

933   Histamine H4 Receptor Antagonists are Superior to H1R Antagonists in the Attenuation of Experimental Allergic Pruritus

P. J. Dunford, K. N. Williams, R. L. Thurmond; Johnson & Johnson PRD, San Diego, CA.

934   Analysis of Discrete Regulatory T Cell Subsets in Patients with Atopic Dermatitis Reveals Th2-Promoting Properties

A. J. Reefer, S. M. Satinover, J. Nguyen, M. D. Solga, J. Lannigan, B. Wilson, J. A. Woodfolk; University of Virginia, Charlottesville, VA.

935   Histamine 4 Receptor (H4R) Antagonism Reduces Edema In A Th2 And IgE Dependent Model Of Atopic Dermatitis

J. M. Cowden, M. Zhang, R. L. Thurmond, P. J. Dunford; Johnson and Johnson, San Diego, CA.

Oral Abstract Session

4605

Monday, February 26, 2007

1:45 PM - 3:00 PM

Food Allergy and Immunologic GI Disorders

936   Dendritic Cell Subsets In The Development Of Allergic Sensitization To Food Allergens In Mice

A. Blazquez Gonzalez, M. Berin; Mount Sinai School of Medicine, New York, NY.

937   Effect of Partially Hydrolyzed Formula in Atopy Prevention of High Risk Infants Identified by Atopic Risk Score

N. Pitaksit, P. Tansupapol, T. Tongkaew, P. Chatchatee, J. Ngamphaiboon; Allergy and Immunology Division, Department of Pediatrics, King Chulalongkorn Memorial Hospital, Bangkok, THAILAND.

938   DBPCFCs In Children With A History Of Anaphylaxis To Foods: Are They Necessary And Safe?

B. J. Vlieg-Boerstra, E. J. Duiverman, S. van der Heide, C. M. A. Bijleveld, J. Kukler, A. E. J. Dubois; University Medical Center Groningen, Groningen, THE NETHERLANDS.

939   Examining Attitudes and Behaviors in Adolescents with Food Allergy: A Telephone Survey

A. S. Murthy ¹, R. Seshadri^1,2, J. A. Pongracic¹; ¹Children's Memorial Hospital, Chicago, IL, ²The Mary Ann and J. Milburn Smith Child Health Research Program, Chicago, IL.

940   Il-13 Is Overexpressed In Eosinophilic Esophagitis And Induces Eotaxin-3 Expression In Esophageal Epithelial Cells

C. Blanchard ¹, M. K. Mingler¹, P. Putnam¹, M. E. Rothenberg^1,2; ¹Cincinnati Children's Hospital, Cincinnati, OH, ²University of Cincinnati, College of Medicine, Cincinnati, OH.

941   Gastrointestinal Priming and Recruitment of Th2 Lymphocytes in Food Allergy

A. K. Knight ¹, A. B. Blazquez², S. Zhang², L. Mayer², H. A. Sampson², M. C. Berin²; ¹Louisiana State University Health Sciences Center, Shreveport, LA, ²Mount Sinai School of Medicine, New York, NY.

Oral Abstract Session

4606

Monday, February 26, 2007

1:45 PM - 3:00 PM

Cytokines as Therapeutic Targets in Allergic Disease

942   Overexpression of ClC-3 Channels Prevent TGF-β-induced Apoptosis in Human Airway Epithelial Cells

G. Cheng ¹, M. Kim¹, B. Chaudhari¹, D. K. Agrawal^1,2; ¹Dept. of Biomedical Science, Creighton University School of Medicine, Omaha, NE, ²Dept. of Internal Medicine, Creighton University School of Medicine, Omaha, NE.

943   IL-4Ra, IL-13 and IL-10 Polymorphisms in Allergic Bronchopulmonary Aspergillosis

A. P. Knutsen, B. Kariuki, M. R. Shah; St. Louis University Health Sciences, Saint Louis, MO.

944   Lymphotacin (XCL1) Improves Suppressive Function of Regulatory T Cells from Allergic Asthmatics

S. W. Berquist; Stanford University, Stanford, CA.

945   A Synthetic Non-peptide Compound Targeting CCR5 Prevents the Development of Asthma in a Murine Model

Y. Suzaki, K. Hamada, Y. Kai, H. Kimura; Nara Medical University, 840 Shijo Kashihara Nara, JAPAN.

946   Allergy-driven Alternative Splicing of Interleukin-13 Receptor Alpha 2 Yields Distinct Membrane and Soluble Forms

Y. Tabata, W. Chen, M. R. Warrier, A. M. Gibson, M. O. Daines, G. K. Khurana Hershey; Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

947   Inflammatory Cytokines Regulate Glucocorticoid Receptor [gr] via Differential Phosphorylation of Serine Residues In the AF1 Domain: Possible Role In Steroid Insensitive Asthma

R. J. Hasan, B. T. Ameredes, W. J. Calhoun; Division of Allergy, pulmonary, Immunology, CCM and Sleep. University of Texas Medical Branch, Galveston, TX.

Oral Abstract Session

4607

Monday, February 26, 2007

1:45 PM - 3:00 PM

Mechanisms of Chronic Rhinosinusitis

948   Analysis of the TLR2 Signaling Pathway in Nasal Epithelial Cells from Patients with Chronic Rhinosinusitis (CRS)

L. C. Grammer, B. Tancowny, Q. Truong-Tran, J. Lee, A. Peters, K. Harris, D. Conley, R. Kern, R. Schleimer; Northwestern University Feinberg Sch. Med., Chicago, IL.

949   Nasal Epithelial Gene Expression In Response To Cigarette Smoke Extract And Toll-Like Receptor Agonists: Relevance To Chronic Rhinosinusitis (CRS)

D. L. Hamilos; Mass Gen Hospital/Harvard Med Sch, Boston, MA.

950   B cell-activating Factor of the TNF Family (BAFF) Expression in Chronic Rhinosinusitis with Nasal Polyps

R. P. Schleimer ¹, A. Kato¹, A. Tripathi¹, B. Tancowny¹, L. Suh¹, R. Carter¹, M. Agashe¹, K. E. Harris¹, D. Conley², R. Kern², L. C. Grammer¹; ¹Allergy-Immunology Division, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, IL.

951   Staphylococcus Aureus Enterotoxin B Stimulation In Nasal Polyps

J. Patou, T. Van Zele, G. Holtappels, P. Gevaert, P. Van Cauwenberge, C. Bachert; Upper Airways Research laboratory, Department of Otorhinolaryngology, Ghent University, Ghent, BELGIUM.

952   Histologic Examination Reveals Distinct Disease Subsets of Chronic Sinusitis

S. B. Early, J. Han, L. Borish, J. Steinke; University of Virginia, Charlottesville, VA.

953   Regulatory Cytokines In Chronic Rhinosinusitis With And Without Nasal Polyps

K. Scheckenbach, A. Chaker, M. Wagenmann; Heinrich-Heine-University Duesseldorf, Duesseldorf, GERMANY.

Poster Session

5201

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Asthma Therapy II

954   In Vitro Metabolism of Ciclesonide in the Upper and Lower Airways

R. Nave ¹, H. Sato², E. Mutch³, T. Nonaka², S. Nishimura², H. Muroga², Y. Katsuura², N. McCracken¹; ¹Altana Pharma AG, Konstanz, GERMANY, ²Teijin Pharma Limited, Tokyo, JAPAN, ³University of Newcastle, Newcastle upon Tyne, UNITED KINGDOM.

955   The Preferred Regimen Of Corticosteroid Used By Practicing Community Physicians For Treatment Of Acute Asthma In Children

P. Britto-Williams ¹, C. Williams², R. Thomas¹, M. Pansare¹; ¹Wayne State University, Detroit, MI, ²Henry Ford Bon Secour Hospital, Detroit, MI.

956   Efficacy of High-Dose Continuous Nebulized Levalbuterol for Pediatric Status Asthmaticus

T. Andrews, E. McGintee, L. Tyler, M. Mittal, A. Chew, N. Pawlowski, J. Zorc; The Children's Hospital of Philadelphia, Philadelphia, PA.

957   Effect of Gly16Arg β2-Adrenergic Receptor Variation on Response to Formoterol Administered Alone or in Combination With Budesonide in Patients With Moderate to Severe Persistent Asthma

M. Goldman ¹, R. Lawrance², H. Ambrose²; ¹AstraZeneca, Wilmington, DE, ²AstraZeneca, Alderley Park, UNITED KINGDOM.

958   Effectiveness of, Adherence to and Satisfaction with Montelukast Treatment in Allergic Rhinitis Patients with Uncontrolled Asthma Symptoms while on Treatment with Low Dose Inhaled Corticosteroids

C. Koch ¹, A. Kaplan², J. Sampalis³, E. Psaradellis³, A. McIvor⁴; ¹Merck Frosst Canada Ltd., Pointe-Claire, PQ, CANADA, ²Investigator, Richmond Hill, ON, CANADA, ³JSS Research Inc., Montreal, PQ, CANADA, ⁴MacMaster University, Hamilton, ON, CANADA.

959   Effects of Low Dose Fluticasone/Salmeterol Combination (Advair 100/50) on Surrogate Inflammatory Markers in Mild Persistent Asthma

M. A. Pasha ¹, S. Patel¹, H. Jafri², P. Feustel¹, D. Sarathchandra¹, T. Smith¹, P. Malone¹, F. Jourd'heuil¹, D. Jourd'heuil¹; ¹Albany Medical College, Albany, NY, ²U.T. Southwestern Medical Center, Dallas, TX.

960   Effects of KP-496, a Novel Dual Antagonist for Cysteinyl Leukotriene Receptor (CysLT1R) and Thromboxane A2 Receptor (TP), on Porcine Pancreas Elastase Induced Emphysema in Mice

S. Kurokawa, T. Okuda, M. Amakawa, M. Suda, T. Murata, Y. Hiyama; Kaken Pharmaceutical CO.,LTD., Kyoto, JAPAN.

961   Prevention of Exercise-induced Bronchoconstriction by a Single Dose of Montelukast or Salmeterol

D. S. Pearlman ¹, C. Villaran², T. Loeys³, C. Legrand³, T. F. Reiss³, G. Philip³; ¹Colorado Allergy and Asthma Centers, Denver, CO, ²Clinica Ricardo Palma, Lima, PERU, ³Merck Research Labs, Rahway, NJ.

962   Soluble Adhesion Molecules And Cd40l In Asthma And Copd

J. V. Garmendia ¹, D. Moreno², N. E. Larocca¹, C. M. Tálamo³, J. B. De Sanctis¹; ¹Instituto de Inmunología. Universidad Central de Venezuela, Caracas, VENEZUELA, ²Cátedra de Fisiopatología del Instituto de Medicina Experimental y Servicio de Neumonología del Hospital Universitario de Caracas. Universidad Central de Venezuela, Caracas, VENEZUELA, ³Servicio de Neumonología del Hospital Universitario de Caracas. Facultad de Medicina. Universidad Central de Venezuela, Caracas, VENEZUELA.

963   The Effect of Proton Pump Inhibitor on the Exhaled Breath Condensate pH and QOL in QUEST Questionnaire-Positive Asthmatics

T. Yano, H. Nagase, J. Nakano, H. Yoshihara, K. Yamamura, S. Ueki, O. Ohbayashi, M. Nakajima, T. Adachi, K. Ohta; Teikyo University School of Medicine, Tokyo, JAPAN.

964   Budesonide and Formoterol in One Metered-Dose Inhaler Improves Health-Related Quality of Life in Adults with Mild to Moderate Persistent Asthma Previously Treated with Inhaled Corticosteroids

H. Nelson ¹, K. Murphy², B. Parasuraman³, R. Boggs³, C. Miller³, L. O'Dowd³; ¹National Jewish Medical and Research Center, Denver, CO, ²Midwest Allergy and Asthma Clinic, Omaha, NE, ³AstraZeneca, Wilmington, DE.

965   Perceived Onset of Effect of Budesonide and Formoterol Administered via One Pressurized Metered-dose Inhaler in Patients With Asthma Previously Receiving Inhaled Corticosteroids

N. K. Leidy ¹, D. L. Patrick², R. Boggs³, B. Parasuraman³, L. O'Dowd³; ¹United BioSource Corporation, Bethesda, MD, ²University of Washington, Seattle, WA, ³AstraZeneca, Wilmington, DE.

966   Efficacy Of Ventolin^® HFA MDI Cumulative Dosing In Children

A. Davis, W. Lincourt, R. Trivedi, A. Ellsworth, C. Crim; GlaxoSmithKline, RTP, NC.

967   The Safety of Home Therapy with Subcutaneous Anti-Immunoglobulin E Antibody Omalizumab in Twenty-five Patients with Allergic Asthma

M. I. Liebhaber, Z. Dyer; Sansum Santa Barbara Clinic, Santa Barbara, CA.

968   Prophylactic Effects of the Chinese Herbal Formula, ASHMI, in a Murine Model of Late Onset Atopic Asthma

P. J. Busse ¹, T. Zhang¹, K. Srivastava¹, B. Schofield², X. Li¹; ¹Mount Sinai School of Medicine, New York, NY, ²Bloomberg School of Publich Health, Baltimore, MD.

969   How Potent Are Inhaled Steroids? Cushing's Syndrome Due To Interaction Between Inhaled Fluticasone And Ritonavir In A Child With Human Immunodeficiency Virus (HIV) Infection

I. S. Randhawa, R. M. Ferdman, J. A. Church; Childrens Hospital Los Angeles, Los Angeles, CA.

970   Effect of long acting β2 agonist patch, Asthma

H. Lee; Cheil General Hospital, Seoul, REPUBLIC OF KOREA.

971   Comparative Bronchodilatory Effects of Formoterol Dry-Powder Inhaler (DPI) Versus the Combination of Formoterol and Budesonide Pressurized Metered-Dose Inhaler (pMDI)

W. S. Mezzanotte ¹, C. J. Miller¹, S. Senn²; ¹AstraZeneca, Wilmington, DE, ²University of Glasgow, Glasgow, UNITED KINGDOM.

972   Comparative Assessment of Asthma Control With Budesonide and Formoterol in One Pressurized Metered-Dose Inhaler (pMDI) Versus Budesonide and Formoterol in Individual Inhalers and Placebo

J. Corren ¹, P. E. Korenblat², C. J. Miller³, C. D. O'Brien³, W. S. Mezzanotte³; ¹Allergy Research Foundation, Los Angeles, CA, ²The Clinical Research Center, St Louis, MO, ³AstraZeneca, Wilmington, DE.

973   Cardiac Safety of Ventolin^® HFA in Children

J. Hedrick¹, A. Davis ², W. Lincourt², R. Trivedi², A. Ellsworth², C. Crim²; ¹Kentucky Pediatric/Adult Research, Bardstown, KY, ²GlaxoSmithKline, RTP, NC.

974   Measured Onset of Bronchodilation With Budesonide and Formoterol Administered via One Pressurized Metered-dose Inhaler (pMDI) in Patients With Asthma Previously Receiving Inhaled Corticosteroids

H. B. Kaiser ¹, C. J. Miller², L. O'Dowd²; ¹Clinical Research Institute, Minneapolis, MN, ²AstraZeneca, Wilmington, DE.

975   Effect of a Novel Medical Food (NMF) on Biomarkers of Inflammation and Airway Hyperresponsiveness in Children with Mild Persistent Asthma

R. Covar ¹, B. Macomber¹, L. Stewart¹, M. Gleason¹, K. Engelhardt¹, J. Murphy¹, A. Liu¹, S. Wood², S. DeMichele², E. Gelfand¹, S. Szefler¹; ¹National Jewish Med Res Ctr, Denver, CO, ²Ross Products, Abbott Laboratories, Columbus, OH.

976   The Significance of the Initiating Time of Inhaled Corticosteroid in Asthma Treatment

J. Jung ¹, J. Kim², J. Lee³; ¹Dong-A University Hospital, Busan, REPUBLIC OF KOREA, ²Ulsan University Hospital, Ulsan, REPUBLIC OF KOREA, ³Masan Samsung Hospital, Masan, REPUBLIC OF KOREA.

977   Stability of IgE Levels during Acute Asthma: Implications for Initiation of Omalizumab Therapy after the Emergency Department Visit

C. J. Ahn¹, B. M. Baumann², R. F. Kysia³, M. S. Radeos⁴, K. Stiffler⁵, C. A. Camargo, Jr. ¹; ¹Massachusetts General Hospital, Boston, MA, ²Cooper University Hospital, Camden, NJ, ³Cook County Hospital, Chicago, IL, ⁴Lincoln Medical and Mental Health Center, Bronx, NY, ⁵Summa Health System, Akron, OH.

978   Prescribing of Fluticasone Propionate/Salmeterol Combinations as Initial Therapy for Patients With Asthma in a Commercially-Insured Population

H. S. Friedman ¹, T. K. Wilcox², G. Reardon³, S. Crespi⁴, B. P. Yawn⁵; ¹Analytic Solutions, LLC, New York, NY, ²United Biosource Corporation, Bethesda, MD, ³Informagenics, LLC, Worthington, OH, ⁴Schering-Plough Corporation, Kenilworth, NJ, ⁵Olmsted Medical Center, Rochester, MN.

979   Management of Patients with Bronchial Asthma, Elevated IgE and Eosinophilia Including Patients with Churg Strauss Syndrome

V. V. Chopyak ¹, G. O. Potomkina¹, K. O. Lishchuk-Yakymovych¹, R. R. Holovyn¹, I. V. DuBuske², L. M. DuBuske²; ¹Lviv National Medical University, Lviv, UKRAINE, ²Immunology Research Institute of New England, Gardner, MA.

Poster Session

5202

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Immunodeficiency II

980   Reversible Pan-hypogammaglobulinemia Associated With The Antiepileptic Levetiracetam (keppra)

A. E. Azar ^1,2, Z. K. Ballas^1,2; ¹University of Iowa Hospitals and Clinics, Iowa City, IA, ²Veterans Affairs Medical Center, Iowa City, IA.

981   Efficacy of IGIV in Patients With IgG Subclass Deficiency and/or Antibody Deficiency in a One-Year Open Label Study of Quality of Life, Innate Immunity, and Correction of Subclass/Antibody Levels

C. A. Greenwell ¹, R. Mehta², J. D. Hester³, G. V. Yamshchikov³, J. F. Halsey³, N. I. Abdou¹; ¹Center for Rheumatic Disease, Allergy, and Immunology, Kansas City, MO, ²University of Missouri Kansas City School of Medicine, Kansas City, MO, ³IBT Reference Lab, Lenexa, KS.

982   Why Are Patients Referred to A Non HIV Adult Immunodeficiency Clinic?

J. B. Hagan, R. S. Abraham, M. A. Park, G. W. Volcheck, D. E. Maddox, J. H. Butterfield, J. T. C. Li; Mayo, Rochester, MN.

983   Autoimmune Lymphoproliferative Syndrome (ALPS) in a Patient with Common Variable Immunodeficiency (CVID): Fas Deficiency with Increased Apoptosis

M. B. Narra ¹, N. I. Abdou²; ¹UMKC School of Medicine, Kansas City, MO, ²Center for Rheumatic Disease, Allergy and Immunology, Saint Luke's Hospital, Kansas City, MO.

984   A Pilot Study of Quality of Life, Mood, Sleepiness and Fatigue in Patients with Primary Immunodeficiency Receiving IVIG

A. S. Kanani, R. R. Schellenberg, D. F. Stark; University of British Columbia, Vancouver, BC, CANADA.

985   11q Terminal Deletion Disorder (Jacobsen Syndrome) with Combined Variable Immunodeficiency (CVID)

G. Puglisi, A. L. Cox, V. R. Bonagura; North Shore - Long Island Jewish Health System, Great Neck, NY.

986   Absent B-cells and Decreased T-cells in a Family With Hypogammaglobulinemia: A Unique Form of Combined Immune Deficiency?

M. H. Land, R. Tachdjian, E. Lin, M. Riedl, R. L. Roberts; UCLA Medical Center, Los Angeles, CA.

987   Recurrent Facial Herpes Simplex Infections in a 4 year Old Female with a Functional Natural Killer Cell Deficiency

A. Marks, R. Hostoffer, Jr.; Case Western Reserve University, Cleveland, OH.

988   IgG Subclasses Deficiency's Clinical Expressions

G. Manfredi, C. Derosa, E. Ventura, R. Caso; Religious Gen. Hospital “F. Miulli”, Acquaviva (BA), ITALY.

989   Partial DiGeorge Anomaly (DGA) with an Unusual Immune Phenotype is Diagnosed in an Adult Parent, after the Diagnosis of his Daughter

B. A. Becker, A. P. Knutsen; Saint Louis University School of Medicine, Saint Louis, MO.

990   Idiopathic CD4+ Lymphocytopenia in a Patient with Progressive Multifocal Leukoencephalopathy Treated with Cidofovir

S. J. McEldowney, R. K. Bush; University of Wisconsin Hospital and William S. Middleton Memorial Veterans Hospital, Madison, WI.

991   Griscelli Syndrome: A Case Report

J. Y. Zhang ¹, A. J. MacGinnitie¹, B. Ackermann², C. Galambos³; ¹Children's Hospital of Pittsburgh, Allergy and Immunology, Pittsburgh, PA, ²Children's Hospital of Pittsburgh, Pittsburgh, PA, ³Children's Hospital of Pittsburgh, Pathology, Pittsburgh, PA.

992   Hereditary Angioedema: An often Misdiagnosed Dsease

Y. X. Zhi, h. y. Zhang; Peking Union Medical College Hospital, Beijing, CHINA.

993   Heart Surgery Reverses Hypogammagolulinemia And CD4-cytopenia By Correcting Protein-losing Enteropathy

K. Y. Wang, R. L. Roberts; UCLA Medical Center, Los Angeles, CA.

994   A Child with WHIM Syndrome (Warts, Hypogammaglobulinemia, Infections, and Myelokathexis) and a Family History of Cervical Dysplasia Suggesting Generalized Susceptibility to Human Papilloma Virus Serotypes

L. E. Montelibano ¹, K. Paris¹, R. Howes², R. U. Sorensen¹; ¹LSU Health Sciences Center, New Orleans, LA, ²LSU Health Sciences Center - University Medical Center, Lafayette, LA.

995   Autosomal Recessive Chronic Granulomatous Disease in a Two Week Old Arabic Female and Unusual Carrier State Detected on Flow Cytometry of Asymptomatic Siblings

N. Mireku, E. A. Secord; Children's Hospital of Michigan, Detroit, MI.

996   A Novel Case of Gaucher's Disease Associated with Hypogammaglobulinemia

S. Jariwala, J. Fodeman, D. Rosenstreich, G. Hudes, K. Ahuja; Division of Allergy and Immunology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY.

997   Major Histocompatibility Complex Class II (MHC II) Deficiency in a Child with Panhypogammaglobulinemia and Lymphopenia

A. E. Bailey ¹, J. J. H. Bleesing², S. M. Jones¹, T. T. Perry¹, U. M. Nagarajan¹, A. M. Scurlock¹; ¹UAMS/Arkansas Children's Hospital, Little Rock, AR, ²Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

998   Severe Mycobacterium Fortuitum Lung Disease Resembling Interstitial Pneumonitis in an 8 Year-old Child - Dilemmas in Diagnosis and Treatment

B. M. Peralejo, H. Aguila, L. Geng, H. Jyonouchi; University of Medicine and Dentistry of New Jersey, Newark, NJ.

999   Nonmyeloablative Matched Unrelated Donor Hematopoietic Cell Transplant for Late-Onset Omenn's with Novel RAG Mutation

D. A. Wierzbicki ¹, J. A. Cox², I. R. Rainville³, R. P. Nelson, Jr.⁴, M. T. de la Morena¹; ¹Division of Allergy and Immunology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, ²Pediatric Hematology/Oncology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, ³Correlagen Diagnostics, Inc, Cambridge, MA, ⁴Division of Hematology/Oncology, Indiana University School of Medicine and the Indiana Cancer Center, Indianapolis, IN.

1000   Infliximab Treatment For Common Variable Immunodeficiency (CVID) With Sarcoid-Like Granulomatous Disease: A Pediatric Case Report

R. J. Marchlewski, L. Katz, A. Shende, B. Gottlieb, V. R. Bonagura; North Shore-Long Island Jewish Health System, Great Neck, NY.

1001   Severe Hypogammaglobulinemia And Absent B Cells in an Adult Patient: A Case Report

S. R. Iyengar ¹, B. G. Blackburn², D. B. Lewis²; ¹Children's Hospital of Boston, Boston, MA, ²Stanford University Medical Center, Stanford, CA.

1002   Sprue-like Disease Associated with T-Cell Clonality as a Cause of Death in a Patient with Common Variable Immunodeficiency

J. D. Mozena; University of Virginia, Charlottesville, VA.

1003   [Withdrawn]

1004   Granulomatous Disease Mimicking Angioedema in a Patient with Long-Standing Common Variable Immunodeficiency

D. S. Landa, B. Kaplan; North-Shore Long Island Jewish Health System, Great Neck, NY.

1005   A Novel Missense Mutation in CYBB gene in Chronic Granulomatous Disease

J. P. DeMore ¹, Y. Dong², D. B. Lewis², J. E. Gern¹, C. M. Seroogy¹; ¹University of Wisconsin Hospital and Clinics, Madison, WI, ²Stanford School of Medicine, Stanford, CA.

1006   Acquired C1 Esterase Inhibitor Deficiency in a Patient with Systemic Lupus Erythematosus (SLE)

J. V. Giannobile ¹, B. J. Fessler², J. R. Bonner¹; ¹University of Alabama at Birmingham, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Birmingham, AL, ²University of Alabama at Birmingham, Department of Medicine, Division of Immunology and Rheumatology, Birmingham, AL.

1007   Glucocorticoid Receptor [gr] Translocation Regulation by Inflammatory Cytokines

N. Bulayeva, B. T. Ameredes, W. J. Calhoun; University of Texas Medical Branch, Galveston, TX.

Poster Session

5203

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Dendritic Cells, Biological Therapies, and Innate Signals

1008   TLR2 Activation By Supernatant From Bifidobacterium Breve Modulates Maturation And Survival Of Human DCs Via Differential Effects On PI3Kinase, p38 And ERK Pathways

C. Hoarau ¹, L. Martin¹, F. Velge-Roussel¹, C. Gontier², Y. Lebranchu¹; ¹Public Hospital, Tours, FRANCE, ²Bledina, Stennvorde, FRANCE.

1009   ANP-NPRA Signaling Modulates Immunity By Altering TLR-2 Expression In Human Dendritic Cells (DCs)

X. Cao, W. Zhang, R. F. Lockey, S. S. Mohapatra; USF, Tampa, FL.

1010   Interferon-a Alters IgE Receptor-dependent Cytokine Production by Human Circulating Monocytoid Dendritic Cells

T. V. Le, B. A. Plunkett, R. A. Wood, S. K. Huang, J. T. Schroeder; Johns Hopkins School of Medicine, Baltimore, MD.

1011   Role Of Dendritic Cells In Drug Metabolism

C. Mayorga ¹, R. R-Pena¹, G. Perez-Cataldo², M. Castell², M. J. Torres³, C. Antunez¹, P. Chaves¹, J. V. Castell², M. Blanca³; ¹Research Laboratory, Fundacion IMABIS-Carlos Haya Hospital, Málaga, SPAIN, ²Experimental Hepathology Unit, University Hospital La Fe, Valencia, SPAIN, ³Allergy Service, Carlos Haya Hospital, Málaga, SPAIN.

1012   Are the Pro-Allergic Properties of House Dust Mite Allergen Explained by the Adjuvant Effects of Mite DNA?

S. Satinover, A. Reefer, K. Hulse, H. Carper, T. Platts-Mills, J. Woodfolk; University of Virginia, Charlottesville, VA.

1013   Gene Expression Profiles in The Plasmacytoid Dendritic Cells Stimulated with Lactobacillus GG or E.coli

S. Toki, H. Saito, K. Matsumoto; National Research Institute for Child Health and Development, Tokyo, JAPAN.

1014   Elucidating the Mechanisms of IL-12 Mediated Alterations of the Tumor Microenvironment

E. W. Sorensen; University of Rochester, Rochester, NY.

1015   Allergen and Antibody Mediated Desensitisation for Mucosal-Induced Respiratory Allergy

W. R. Thomas, P. T. Cunningham, C. E. Elliot, J. C. Lenzo, P. G. Holt; Telethon Institute for Child Health Research, West Perth, AUSTRALIA.

1016   Measurement of Enterovirus-Specific IgG in Intravenous Immunoglobulin Preparations

M. R. Kaplan ¹, R. Arora², M. R. Nelson¹; ¹Walter Reed Army Medical Center, Washington, DC, ²William Beaumont Army Medical Center, El Paso, TX.

1017   New Treatment Strategy for Systemic Mastocytosis

R. Sullivan, D. J. Stechschulte; University of Kansas, Kansas City, KS.

1018   Rituximab in Lupus Pneumonitis: Breathe Easier

A. L. B. Hersh, P. Efthimiou; UMDNJ - Newark, NJ, Newark, NJ.

1019   Peptide Immunotherapy: The Use of Bovine Colostrum Proline-Rich Polypeptides in Cytokine Modulation for the Alternative Relief of Allergic Symptoms

A. M. Keech; Advanced Protein Systems, Phoenix, AZ.

1020   Mast Cells co-cultured with Astrocytes Evokes the Releases of Mediators via Intracellular Calcium Signal Pathway

D. Kim^1,2, Y. Ahn³, Y. Lee^1,2, J. Ro ^1,2; ¹Sungkyunkwan University School of Medicine, Suwon, REPUBLIC OF KOREA, ²Samsung Biomedical Research Institute, Suwon, REPUBLIC OF KOREA, ³Eulji University School of Medicine, Seoul, REPUBLIC OF KOREA.

1021   (1) The Plasma Membrane Shuttling of CAPLI in Mast Cell Activation

M. NAKANISHI; Aichi Gakuin University, Nagoya, JAPAN.

1022   The Role of Innate Immunity in Otitis Media

M. L. Hernandez; University of California, San Diego, La Jolla, CA.

1023   Identification of Protein Related with Maturation of Mouse Bone Marrow-Derived Mast Cells

S. Ryu^1,2, D. Kim^1,2, B. Lee³, J. Ro ^1,2; ¹Sungkyunkwan University School of Medicine, Suwon, REPUBLIC OF KOREA, ²Samsung Biomedical Research Institute, Suwon, REPUBLIC OF KOREA, ³Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA.

1024   Basic Fibroblastic Factor-induced Neurite Outgrowth Suppressed by Nicotine via Inhibition of Nitric Oxide Synthesis in H19-7 Cells

H. Lee, J. Oh, J. Han, Y. Koh, S. Park, J. Cho, D. Oh; Hanyang University Medical Center, Seoul, REPUBLIC OF KOREA.

1025   Activity Of TLR Pathways In Healthy Children And Adults And Patients Taking Immunosuppressive Drugs

N. Khan, M. Helbert, P. D. Arkwright; University of Manchester, Manchester, UNITED KINGDOM.

1026   CATERPILLERS R US: Novel Regulators of Inflammation and Apoptosis Preserved from Plants to Humans

J. P. Y. Ting; Lineberger Comprehensive Cancer Center CB#7295, Chapel Hill, NC.

1027   Characterisation of a New Intravenous Immunoglobulin

M. López, P. Ristol, J. I. Jorquera; INSTITUTO grIFOLS, S.A., Parets del Vallès, Barcelona, SPAIN.

1028   Human Keratinocytes Secrete TNFa Stimulated With Cytomix and D. Pteronyssinus Extract

M. Frieri, A. Capetandes; Nassau University Medical Center-North Shore Long Island Jewish Health Care System, East Meadow, NY.

1029   Capacity of Human Intravenous Immunoglobulin (IGIV3I) Production Process to Eliminate an Experimental TSE-Model Agent

J. M. Diez, H. Biescas, S. Caballero, R. Gajardo, J. I. Jorquera; Instituto Grifols, Barcelona, SPAIN.

1030   Sophorolipids Decrease IgE Production in U266 Cells by Downregulation of BSAP (Pax5), TLR-2, STAT3 and IL-6

M. Hagler¹, T. A. Smith-Norowitz¹, S. Chice¹, S. R. Wallner², D. Viterbo¹, C. M. Mueller¹, R. Gross², M. Nowakowski¹, R. Schulze¹, M. E. Zenilman¹, M. H. Bluth ¹; ¹SUNY Downstate Medical Center, Brooklyn, NY, ²Polytechnic University, Brooklyn, NY.

1031   Viral Safety Studies of a New Human Intravenous Immunoglobulin (IGIV3I)

H. Biescas, S. Caballero, N. Domingo, R. Gajardo, J. I. Jorquera; Instituto Grifols, Parets del Vallès. Barcelona, SPAIN.

1032   Cytokine and Chemokine Responses of Type II Alveolar Epithelial Cells (AEC) in Monocrotaline-Induced Pulmonary Fibrosis

R. N. Kamal ¹, A. Molteni¹, M. Zoubine¹, M. Norkin¹, S. Reppert², Y. Xue², R. Baybutt², B. Herndon², A. Shnyra¹; ¹University of Missouri - Kansas City School of Medicine, Kansas City, MO, ²Kansas State University, Manhattan, KS.

Poster Session

5204

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

A Medley of EORD Topics

1033   Prevalence and Titer of Specific IgE Antibodies in Relation to Total Serum IgE: Evaluation of Sensitization to Allergens Derived from Domestic Mice

L. Naccara¹, P. Heymann¹, M. Carter², A. Litonjua³, E. Peters⁴, S. Satinover¹, E. Erwin¹, T. A. E. Platts-Mills ¹; ¹University VA Medical Center, Charlottesville, VA, ²NIH/NIAID, Bethesda, MD, ³Harvard Medical Center, Boston, MA, ⁴Allergy and Asthma Consultants, Austin, TX.

1034   Sequence Analysis of Monoclonal Antibodies Against Group 1 Dust Mite Allergens

K. T. Williams, M. D. Chapman, A. Pomés; INDOOR Biotechnologies, Inc., Charlottesville, VA.

1035   Gender and Age Differences in Component Resolved Sensitization Pattern to Grass Pollen Allergens

A. Marknell DeWitt ¹, C. Nordenhall², T. Lundgren¹, M. Nordlund², G. Lilja², J. Lidholm¹; ¹Phadia AB, Uppsala, SWEDEN, ²Department of Paediatrics, Sachs' Children's Hospital, Stockholm, SWEDEN.

1036   Bcg's Scar and Allergic Sensitization in High Risk Atopic Children

C. S. K. La Scala, V. V. E. Rullo, L. C. L. de Oliveira, D. Solé; Sao Paulo Federal University, Sao Paulo, SP, BRAZIL.

1037   Simultaneous Detection of Total and Allergen-specific IgE Using Fluorescent Multiplex Array Technology

E. M. King, C. Earle, A. Tsay, L. Vailes, M. D. Chapman; INDOOR Biotechnologies Inc., Charlottesville, VA.

1038   Settled Barn and Home Dust Induces Distinct Airway Inflammation in Mice not Explained by Endotoxin

M. S. Leino ¹, H. Alenius¹, T. Haahtela², L. von Hertzen², H. Wolff³, M. Salkinoja-Salonen⁴, M. A. Andersson⁴, O. Saris⁴, L. Pylkkänen¹, K. Reijula¹, M. Mäkelä²; ¹Finnish Institute of Occupational Health, Helsinki, FINLAND, ²Department of Allergy, Helsinki University Central Hospital, Helsinki, FINLAND, ³Department of Pathology, Helsinki University Central Hospital, Helsinki, FINLAND, ⁴Department of Applied Chemistry and Microbiology, University of Helsinki, Helsinki, FINLAND.

1039   Microbial Contaminants Contribute to the Inflammatory Effect of Metal Working Fluid in a Murine Model

M. C. Zacharisen ¹, C. S. Barrios², V. P. Kurup^1,2, J. N. Fink¹; ¹Medical College of Wisconsin, Milwaukee, WI, ²Zablocki VA Medical Research Center, Milwaukee, WI.

1040   Effects of Oral Monosodium Glutamate (MSG) in Mouse Models of Asthma and Atopic Dermatitis

J. Yoneda; Ajinomoto co., INC. Institute of Life Sciences, Kawasaki-shi., JAPAN.

1041   Botanical Combination Product Reduces Late-Phase Response To Nasal Allergen Challenge

M. Lemay ¹, Y. Lin¹, R. K. Randolph¹, L. Rozga¹, D. Diaz-Sanchez², D. Krempin¹, J. Corren³; ¹Nutrilite Health Institute, Buena Park, CA, ²Department of Medicine, University of California, Los Angeles, CA, ³Allergy Research Foundation, Los Angeles, CA.

1042   Comparative Analysis of Extract-based Skin Test and IgE detection, Singleplexed Molecule-based IgE Detection and a Molecule-based Microarray System

A. Mari ¹, P. Palazzo¹, D. Pomponi¹, M. Helmer-Citterich¹, D. Zennaro^2,1, M. Giani¹, E. Scala¹; ¹Center for Clinical and Experimental Allergology. IDI-IRCCS, Rome, ITALY, ²Campus-Biomedico University, Rome, ITALY.

1043   Development of a Microarray Assay to Determine the Potency of Allergenic Extracts Using Recombinant Antibodies

N. C. deVore, J. E. Slater; Food and Drug Administration, Rockville, MD.

1044   Exposure To Formaldehyde In Asthmatic And Control Dwellings In The Area Of Strasbourg (France)

C. Marchand ¹, S. Le Calvé¹, P. Mirabel¹, N. Glasser², A. Casset³, N. Schneider³, F. de Blay³; ¹CNRS - Louis Pasteur University, Strasbourg, FRANCE, ²Faculty of Pharmacy, Illkirch, FRANCE, ³Asthma and Allergy Division, Department of Chest Diseases, University Hospital, Strasbourg, FRANCE.

1045   Measurement of Airway Hyperresponsiveness May Be a Incomplete Outcome Parameter in Occupational Asthma

C. Kim, B. Park, J. Cho; Inha University Hospital, Incheon, REPUBLIC OF KOREA.

1046   Occupational Rhinitis and Asthma Caused by Tampico Fibers in a Brush Maker

S. Quirce, M. Fernández-Nieto, C. Pastor, J. Torres, A. Enríquez, J. Sastre; Fundación Jiménez Díaz, Madrid, SPAIN.

1047   Lower Airway Inflammation Assessed by Induced Sputum in a Cluster of Cases Suggestive of Organic Dust Toxic Syndrome

R. Castano, J. L. Malo, C. Lemiere, M. Labrecque, A. Cartier; Hoˆpital du Sacré-Coeur de Montréal, Montréal, PQ, CANADA.

Poster Session

5205

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Drug Allergy II

1048   Is there Adequate Regulation in the Use of Complementary and Alternative Medicines (CAM)?

H. C. G. Wong ^1,2; ¹University of British Columbia, Vancouver, BC, CANADA, ²Vancouver General Hospital, Vancouver, BC, CANADA.

1049   Moxifloxacine-induced Drug Hypersensitivity Syndrome

S. Lee; Dong-A University, Busan, REPUBLIC OF KOREA.

1050   Successful Transcatheter Closure of an Atrial Septal Defect in a Nickel-Allergic Patient

B. Vickery, P. Askenase, F. Kantor, J. Asnes; Yale University, New Haven, CT.

1051   Risk Factors For Adults with a History of Penicillin Allergy

A. J. Apter ¹, F. Wan¹, J. Chittams¹, B. Adelsberg², S. Andrew³, M. Blaiss⁴, M. Columbo⁵, A. Davidson⁶, P. Detjen⁷, B. De Cotiis⁸, D. Dvorin⁹, L. Ford¹⁰, S. Gawchik¹¹, S. Gillman¹², M. Grijnsztein¹³, G. Gross¹⁴, M. Hoffman¹⁵, M. Lanz¹⁶, A. Stillerman¹⁷, P. Takach¹⁸, T. Rebbeck¹; ¹University of Pennsylvania, Philadelphia, PA, ²Connecticut Medical Group, Hamden, CT, ³Mainland Allergy Clinic, Dickinson, TX, ⁴Allergy & Asthma Care, Germantown, TN, ⁵Rohr &Columbo Asthma, Allergy & Immunology Specialists, Bryn Mawr, PA, ⁶Allergy & Asthma Consultants, Mt. Pleasant, TN, ⁷Adult & Pediatric Asthma & Allergy, Kenilworth, IL, ⁸De Cotiis & Grijnszstein, Brick, NJ, ⁹Allergy and Asthma Research of New Jersey, Forked River, NJ, ¹⁰Asthma & Allergy Center, Papillion, NE, ¹¹Crozer Chester Medical Center, Chester, PA, ¹²Sherwin Gillman, Orange, CA, ¹³DeCotiis & Grijnsztein, Brick, NJ, ¹⁴Atlantic Allergy Asthma & Immunology Associates, Ashbury Park, NJ, ¹⁵Allergy, Asthma, and Immunology Associates, Lincoln, NE, ¹⁶Allergy, Asthma, Atopic Dermatitis, Rhinitis, and Sinusitis Clinical Research Center, Coral Gables, FL, ¹⁷Allergy and Asthma Specialists, Minneapolis, MN, ¹⁸Allergy Associates, Chico, CA.

1052   Evidence for Cross-Reactivity Among Proton Pump Inhibitors (PPIs): A Case Report of Hypersensitivity to Three PPIs

A. L. Cox, B. Kaplan; North Shore-Long Island Jewish Health System, Great Neck, NY.

1053   Iodinated Contrast Media Hypersensitivity Diagnosis - Skin Tests and Limphoblastic Transformation Test

A. F. F. Ferrão, R. P. Reis, L. A. Patricio, M. R. Viseu, S. H. Correia, S. H. Correia, M. J. Peres, E. M. Tomaz, F. C. Inácio; Hospital S. Bernardo, Setubal, PORTUGAL.

1054   Desensitization to High-dose Methotrexate (mtx) After Anaphylactoid Reaction, Without Premedication Phase

S. R. Abouhassan ¹, S. Alexander², A. Chouksey²; ¹University Hospitals of Cleveland, Cleveland, OH, ²Rainbow Babies & Children's Hospital, Cleveland, OH.

1055   Human Insulin Allergy of Immediate Type and Insulin-induced Vasculitis In a Patient With Diabetes Mellitus Type 1

D. C. Hatzis ¹, C. Larmou², I. Ioannou², A. Anagnostou - Keramida³, C. Bartsocas¹; ¹Mitera General Hospital, Athens, grEECE, ²Limassol General Hospital, Limassol, CYPRUS, ³Evangelismos General Hospital, Athens, grEECE.

1056   Oral Aspirin Challenge In Acute Myocardial Infarction

D. S. Walia, D. J. Stechschulte; Kansas University Medical Center, Kansas City, KS.

1057   A Case Study of a Lichenoid Drug Eruption due to Oral Cyclosporine

J. S. Swartz, M. Budev, A. Mehta; Cleveland Clinic, Cleveland, OH.

1058   Allergenic Cross-Reactivity between Echinacea and Ragweed

M. B. Fasano; Universtiy of Iowa, Iowa City, IA.

1059   Assessment of Irritant Skin Test Reactions to Common Vaccines

R. A. Wood, R. Setse, N. Halsey; Johns Hopkins University, Baltimore, MD.

1060   Penicillin Skin Testing and Challenges in the Absence of the Major Penicillin Determinant

P. A. Greenberger, A. T. Peters; Northwestern University, Chicago, IL.

1061   Cytokine and Chemokine Expression in the Skin from Patients with Maculopapular Exanthema to Drugs

T. D. Fernández ¹, C. Mayorga¹, J. A. Cornejo-García¹, M. J. Torres², C. Rondon², R. R-Pena¹, S. López¹, E. Martín², M. Blanca²; ¹Research Laboratory. Fundacion IMABIS-Carlos Haya Hospital, Málaga, SPAIN, ²Allergy Service. Carlos Haya Hospital, Málaga, SPAIN.

1062   Predicting Severity of Reactions During Aspirin Desensitization in Patients with Aspirin Exacerbated Respiratory Disease (AERD)

A. P. Hope, R. A. Simon, D. D. Stevenson; Scripps Clinic/Green Hospital, La Jolla, CA.

1063   Cytokine and Transcription Factors Expression in Patients with Delayed Allergic Reactions to Drugs

J. A. Cornejo-Garcia ¹, T. D. Fernandez¹, C. Mayorga¹, M. J. Torres², M. Carballo³, I. Hernan³, C. Rondon², J. L. Rodriguez-Bada¹, E. Martin², M. Blanca²; ¹Research Laboratory, Fundacion IMABIS-Carlos Haya Hospital, Málaga, SPAIN, ²Allergy Service, Carlos Haya Hospital, Málaga, SPAIN, ³Laboratory Service, Tarrasa Hospital, Barcelona, SPAIN.

1064   Rapid Desensitization with Imipenem in Penicillin Allergic Patient

M. R. Aquino, A. Wolff, A. Hersh, L. Bielory; UMDNJ Newark, Newark, NJ.

1065   Prompt Recognition And Timely Diagnosis Of Stevens-Johnson Syndrome

S. J. Schuval ¹, G. Schwarz¹, A. Cox¹, P. Ponda¹, W. Li²; ¹Schneider Children's Hospital, New Hyde Park, NY, ²North Shore University Hospital, Manhasset, NY.

1066   Exaggerated Neurogenic and Allergic Inflammation in the Skin of Rats Treated with Systemically Administered Indomethacin

T. Sakamoto, M. Miyake, R. Kimura, S. Morii, K. Ito; Nagoya University Graduate School of Medicine, Nagoya, JAPAN.

1067   Allergy to Marijuana: Case report

S. Perez-Bustamante, M. Vazquez de la torre, A. Villanueva, R. Pelta, M. Rubio, M. Baeza; Hospital General Universitario Gregorio Marañon, Madrid, SPAIN.

Poster Session

5206

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Angiodema

1068   Hereditary Angioedema and Pancreatitis

D. Chung, P. Busse, M. Oh; Mount Sinai Medical Center, New York, NY.

1069   Hereditary Angioedema: Clinical Aspects in a Brazilian Family

M. Ferraro, M. Thiesen, L. Arruda, W. Sarti; School of Medicine of Ribeirão Preto-University of São Paulo, Ribeirão Preto, BRAZIL.

1070   Fresh Frozen Plasma for the Treatment of Hereditary Angioedema

M. Prematta, J. Gibbs, T. J. Craig, E. Pratt, T. Stoughton; Penn State University, Hershey, PA.

1071   Absolute Bioavailability of Subcutaneously Administered Icatibant, a Selective and Potent Bradykinin B2 Receptor Antagonist

F. Wagner ¹, B. Rosenkranz², J. Knolle²; ¹Charite Research Organisation GmbH, Berlin, GERMANY, ²Jerini AG, Berlin, GERMANY.

1072   Successful Treatment of Chronic Idiopathic Urticaria & Angioedema (CIU), With Xolair (Omalizumab)

C. A. Shapiro ¹, N. S. Kapetanos², E. Sarmiento²; ¹Flushing Hospital Med Ctr, Flushing, NY, ²Advanced Allergy & Asthma Assessment & Diagnostics, P.C., Bayside, NY.

1073   Resolution of Angioedema with Omalizumab

J. W. Blume, S. Kiratseavee, M. F. Sands; University at Buffalo, Buffalo, NY.

1074   Angioedema from Angiotensin I-Converting Enzyme Inhibitors May Have a Genetic Basis in African-American Families

A. Shah, D. Shats, V. Rajput; UMDNJ-Robert Wood Johnson Medical School. Cooper University Hospital, Camden, NJ.

1075   Hereditary Angioedema: Clinical Characteristics and Outcome of 36 Patients

L. K. Tanno, L. H. Pinto, A. A. Motta, J. Kalil, P. Giavina-Bianchi; FMUSP, São Paulo, BRAZIL.

1076   Facial Skin Splitting due to Hereditary Angioedema

G. V. Marcotte; Asthma & Allergy Care of Delaware, Wilmington, DE.

1077   Side Effects Of Long-Term Treatment With Danazol And Stanozolol In Hereditary Angioedema

K. Bork ¹, L. Zingale², H. Farkas³, A. Bygum⁴, L. Bouillet⁵, C. Bucher⁶, T. Caballero⁷, H. Longhurst⁸, E. Nielsen⁹, M. Cicardi²; ¹Department of Dermatology, University of Mainz, Mainz, GERMANY, ²University Hospital, Milano, ITALY, ³University Hospital, Budapest, HUNGARY, ⁴University Hospital, Odense, DENMARK, ⁵University Hospital, Grenoble, FRANCE, ⁶University Hospital, Zurich, SWITZERLAND, ⁷University Hospital, Madrid, SPAIN, ⁸University Hospital, London, UNITED KINGDOM, ⁹University Hospital, Tromso, NORWAY.

1078   Plasmatic Markers Of Coagulation And Fibrinolysis In Patients With C1 Inhibitor Deficiency During Acute Attacks Of Angioedema

A. Zanichelli ¹, M. Cugno^1,2, L. C. Zingale¹, D. Lambertenghi Deliliers¹, L. Maggioni¹, S. Griffini^1,2, M. Cicardi¹; ¹University of Milan, Milano, ITALY, ²Ospedale Maggiore Policlinico, Mangialgalli e Regina Elena, Fondazione IRCCS, Milan, ITALY.

1079   The European Register of Hereditary Angioedema: Experience and Preliminary Results

L. C. Zingale ¹, K. Bork², H. Farkas³, A. Bygum⁴, L. Bouillet⁵, T. Caballero⁶, H. Longhurst⁷, E. Waage Nielsen⁸, B. Bilo⁹, C. Bucher¹⁰, R. Perricone¹¹, M. Cicardi¹; ¹University of Milan, Milan, ITALY, ²University of Mainz, Mainz, GERMANY, ³Semmelweis, Budapest, HUNGARY, ⁴University of Odense, Odense, DENMARK, ⁵CHU de Grenoble, Grenoble, FRANCE, ⁶University Hospital La Paz, Madrid, SPAIN, ⁷St Bartholomew's Hospital, London, UNITED KINGDOM, ⁸Dept. of Anesthesiology, Bodø, NORWAY, ⁹University of Cracow, Cracow, POLAND, ¹⁰University of Zürich, Zürich, SWITZERLAND, ¹¹University of Rome Tor Vergata, Rome, ITALY.

1080   A New Variant of Hereditary Angioedema Involving Macular Edema With Transient Loss of Vision

A. M. Deener, A. Rubinstein; Albert Einstein College of Medicine, Bronx, NY.

1081   Interim Open-Label Results of EDEMA3sm: A Study of Subcutaneous Ecallantide in Patients with Hereditary Angioedema

H. H. Li ¹, R. J. Levy², D. L. McNeil³, T. K. Schmalbach⁴; ¹Institute for Asthma and Allergy, Wheaton, MD, ²Family Allergy & Asthma Center, PC, Atlanta, GA, ³Optimed Research, LLC, Columbus, OH, ⁴Dyax Corp., Cambridge, MA.

1082   Unnecessary Abdominal Surgeries Secondary to Undiagnosed Hereditary Angioedema

K. J. Bowie, M. D. Scarupa, H. H. Li; Institute for Asthma & Allergy, PC, Wheaton, MD.

1083   Diagnosis, Clinical Manifestation and Therapy in Children with Hereditary Angiooedema

I. Martinez-Saguer, E. Rusicke, E. Aygören-Pürsün, T. Klingebiel, W. Kreuz; J.-W. Goethe University Hospital Frankfurt, Germany, Frankfurt, GERMANY.

1084   New Mutations of C1 inhibitor (SERPING1/C1NH) Gene Associated with Hereditary Angioedema in a European Population

C. Drouet ¹, M. Cicardi², E. Pappalardo², N. Monnier¹, O. Roche³, A. Tordai⁴, I. Wagenaar-Bos⁵, R. Perricone⁶, A. Bygum⁷, K. Bork⁸, M. Tosi⁹, M. López-Trascasa³; ¹University Joseph Fourier, Grenoble, FRANCE, ²University of Milan, Milan, ITALY, ³University Hospital La Paz, Madrid, SPAIN, ⁴National Medical Center, Budapest, HUNGARY, ⁵Sanquin Research Center, Amsterdam, THE NETHERLANDS, ⁶University Tor Vergata, Rome, ITALY, ⁷University of Odense, Odense, DENMARK, ⁸Johannes Gutenberg University, Mainz, GERMANY, ⁹University of Rouen, Rouen, FRANCE.

1085   Treatment With Pasteurized C1 Inhibitor Concentrate In Skin Swelling Attacks Of Patients With Hereditary Angioedema

P. Staubach, K. Bork; Department of Dermatology, University of Mainz, Mainz, GERMANY.

1086   Icatibant, a Potent and Selective Bradykinin B2 Receptor Antagonist, is Effective in Treating Patients with Hereditary Angioedema (HAE)

R. J. Levy, S. Goodman; Family Allergy and Asthma Center, P.C., Atlanta, GA.

1087   Prodromal Symptoms Before Exacerbations of Hereditary Angioedema

J. G. Gibbs, T. J. Craig; Penn State College of Medicine, Hershey, PA.

1088   Treatment Of Acute Edema Attacks In Hereditary Angioedema With A Bradykinin Receptor-2 Antagonist (Icatibant)

B. Grundt ¹, K. Bork¹, J. Frank², P. Schlattmann³, J. Nussberger⁴, B. Rosenkranz⁵, L. Dong⁵, J. Knolle⁵, W. Kreuz⁶; ¹Department of Dermatology, University of Mainz, Mainz, GERMANY, ²Department of Dermatology, University Hospital Maastricht, Maastricht, THE NETHERLANDS, ³Institute of Medical Informatics, Biostatistics and Epidemiology, Charite, University of Berlin, Berlin, GERMANY, ⁴Department of Medicine, CHUV, University of Lausanne, Lausanne, SWITZERLAND, ⁵Jerini AG, Berlin, GERMANY, ⁶Center of Pediatrics, University of Frankfurt, Frankfurt, GERMANY.

1089   Discoid Lupus Erythematosus Presenting as Lower Facial Angioedema

N. J. Nam; Columbia University Medical Center, New York, NY.

1090   Episodic Angioedema Associated with Eosinophilia: Successful Treatment with Imatinib Mesylate

S. E. Scranton ¹, C. A. Wild², R. W. England¹; ¹Wilford Hall Medical Center, Lackland AFB, TX, ²David Grant Medical Center, Travis AFB, CA.

1091   Different Causes of Angioedema

P. Nordenfelt, L. Maroti, U. Malkolmsson, J. Björkander; Lansjukhuset Ryhov, Jonkoping, SWEDEN.

1092   Resolution of Symptoms in a Patient with Hereditary Angioedema (HAE) Following Treatment with Icatibant, a Potent and Selective Bradykinin-2 Receptor Antagonist

T. Boehm ¹, W. R. Lumry²; ¹Jerini AG, Berlin, GERMANY, ²AARA Research Center, Dallas, TX.

1093   Lymphoproliferative disease and Acquired C1 inhibitor (C1-INH) deficiency

M. Cicardi, D. Lambertenghi Deliliers, A. Zanichelli, L. C. Zingale, R. Castelli; University of Milan, Milan, ITALY.

Poster Session

5207

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Atopic Dermatitis

1094   Cutaneous Colonization of Staphylococcus aureus at 4 Months of Age and Eczema at 18 Months of Age

S. Suzuki, N. Shimojo, Y. Inoue, T. Arima, M. Tomiita, Y. Kohno; Department of Pediatrics, Graduate School of Medicine and School of Medicine, Chiba University, Chib, Chiba City, JAPAN.

1095   Altered Expression of Epidermal Differentiation Proteins in Atopic Dermatitis compared to Psoriasis or Nonatopic, Healthy Controls

A. De Benedetto ¹, L. Y. McGirt², M. Brummet³, C. Cheadle³, K. C. Barnes³, L. A. Beck¹; ¹Department of Dermatology and Division of Allergy/Immunology and Reumatology, University of Rochester School of Medicine and Dentistry, Rochester, NY, ²Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD.

1096   Association Of Interleukin-10 Gene Promoter Polymorphism In Korean Children With Atopic Dermatitis

K. Kim, J. Hong, J. Park, K. Kim, E. Kim, M. Sohn; Department of Pediatrics, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA.

1097   Transepidermal Water Loss As A Biological Marker In Atopic Dermatitis In Children

J. Gupta ^1,2, E. Grube², A. Lucky², A. Sheth², A. Assa'ad², G. K. Khurana Hershey²; ¹University of Cincinnati, Cincinnati, OH, ²Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

1098   The Relationships among Severity Score, Behavioral Problem, Parental Stress, Maternal Depression, and Social Support in Children with Atopic Dermatitis

M. Shin ¹, S. Chung², S. Lee²; ¹Soonchunhyang university hospital, Bucheon, REPUBLIC OF KOREA, ²Samsung seoul hospital, Seoul, REPUBLIC OF KOREA.

1099   Properties of Circulating Regulatory T Cells Associated with Nascent IgE Responses in Children with Atopic Dermatitis

M. Moloney, S. Satinover, A. Reefer, P. Heymann, D. Murphy, J. Woodfolk; University of Virginia, Charlottesville, VA.

1100   Colonization Of Staphylococcus Aureus On The Cheeks Of 4 Month-old Children At Local Health Centers In Chiba, Japan

N. Shimojo ¹, S. Suzuki¹, M. Tomiita¹, Y. Inoue¹, Y. Arima¹, Y. Kohno¹, Y. Akiba²; ¹Chiba University, Chiba, JAPAN, ²Chiba city institute for enviroment and hygiene, Chiba, JAPAN.

1101   Effect of House Dust Mite (HDM) Avoidance Measure on The Clinical Symptoms in Dogs with Atopic Dermatitis (AD)

S. Kawarai ¹, H. Shirai², M. Sakaguchi³, K. Ohmori¹, N. Yasuda¹, H. Yasuda⁴, K. Ikeda⁵, H. Tsujimoto¹; ¹Department of Veterinary Internal Medicine, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, JAPAN, ²Yamasei corporation, Tokyo, JAPAN, ³Division of Otorhinolaryngology, Graduate School of Medicine and School of Medicine, Chiba University, Chiba, JAPAN, ⁴National Hospital Organization, Sagamihara National Hospital, Kanagawa, JAPAN, ⁵National Institiute of Public Health, Saitama, JAPAN.

1102   Objective Measurement of Sleep Quality, Scratching, and Cytokine Response in Atopic Dermatitis (AD)

B. G. Bender, R. D. Ballard, D. Y. M. Leung; National Jewish Medical and Research Center, Denver, CO.

1103   Development of a Classification System for Atopic Dermatitis (AD): Correlation Between Subjective Symptoms and Disease Extent or Intensity

A. DiDario ¹, E. Yousef²; ¹Thomas Jefferson University, Philadelphia, PA, ²A.I. duPont Hospital for Children, Wilmington, DE.

1104   The Effects of Breast-milk Feeding on Severe Atopic Dermatitis In Korean Infant and Toddler

D. Lim, J. Kim, B. Son, Y. Oh; Inha University, Incheon City, REPUBLIC OF KOREA.

1105   Evaluation of Passive Smoking as a Risk Factor for Severity and Allergic Sensitization Among Atopic Dermatitis Children

A. A. C. Leite ¹, R. M. S. Leite², I. M. C. Costa³, G. M. de Paula², L. O. Rezende²; ¹Instituto Saint Louis, Brasilia, BRAZIL, ²Universidade Catolica de Brasilia, Brasilia, BRAZIL, ³Universidade de Brasilia, Brasilia, BRAZIL.

1106   TARC(CCL17) Augments TNF-α Induced CTACK(CCL27) Production in Infantile Atopic Dermatitis

J. Nakazato, J. Fujiwara, M. Inoue, M. Kishida, N. Shinomiya; Toho University Medical Center, Tokyo, JAPAN.

1107   Effectiveness and Safety Of Recombinant Human Interferon γ Therapy for Moderate to Severe Atopic Dermatitis in Childhood

J. Oh ¹, H. Lee², E. Mo³, J. Lee⁴; ¹Hanyang University Guri Hospital, Kyunggi-do, REPUBLIC OF KOREA, ²Hanyang University, Seoul, REPUBLIC OF KOREA, ³Choongnam National University, Daejeon, REPUBLIC OF KOREA, ⁴Choongnam University, Daejeon, REPUBLIC OF KOREA.

1108   Modulation of Filaggrin by Th2 Cytokines in the Skin of Atopic Dermatitis (AD)

M. D. Howell ¹, B. E. Kim², M. Boguniewicz¹, D. Y. M. Leung¹; ¹National Jewish Medical and Research Center, Denver, CO, ²Sanggye Paik Hospital and Inje University, Seoul, REPUBLIC OF KOREA.

1109   Influence Of Cetirizine On Cytokine Production In Patients With Atopic Dermatitis

G. N. Drannik ¹, A. Kurchenko¹, L. M. DuBuske²; ¹Ukrainian Center for Clinical Immunology, Kiev, UKRAINE, ²Immunology Research Institute of New England, Gardner, MA.

1110   Quantitative Real-time PCR of Staphylococcus aureus DNA Reveals High Levels in Bed, Floor, and Vacuum Dust in Children with Severe Atopic Dermatitis (AD)

A. D. Leung ¹, A. M. Schiltz¹, C. F. Hall¹, A. A. Harris-Deutch¹, A. H. Liu^1,2; ¹National Jewish Medical and Research Center, Denver, CO, ²University of Colorado School of Medicine, Denver, CO.

1111   Severe Refractory Atopic Dermatitis (AD) in Adult Patients, as Compared to Quiescent and Moderate AD is Highly Atopic

B. H. Salt, M. Boguniewicz, D. Y. M. Leung; National Jewish Medical and Research Center, Denver, CO.

1112   The Atopic Dermatitis Questionnaire (ADQ): A 5-minute, Easy-to-use Parent Administered Atopic Dermatitis (AD) Scoring Tool For Home-based Follow Up Compares Well With The SCORAD

K. D. Carel, M. D. Klinnert, K. Kelsay, A. Kelley-Day, N. Miyazawa, E. Gyorkos, K. Walsh, S. Solanyk, E. W. Gelfand, D. L. Bratton; National Jewish Medical and Research Center, Denver, CO.

1113   The Role Of Stat6 In The Murine Model Of Atopic Dermatitis

H. Alenius ¹, T. Savinko¹, S. Lehtimäki¹, N. Fyhrquist-Vanni¹, H. Wolff^1,2, A. Lauerma¹; ¹Finnish Institute of Occupational Health, Helsinki, FINLAND, ²Helsinki University Central Hospital, Helsinki, FINLAND.

1114   Immunologic Phenotype in the Atopic March (AM)

J. M. Spergel ^1,2, M. Boguniewicz³, V. Tsai¹, R. Harbeck³, K. Pinzone¹, S. B. Leung³, D. Y. M. Leung³; ¹Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania School of Medicine, Philadelphia, PA, ³National Jewish Medical and Research Center, Denver, CO.

Poster Session

5208

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Adherence and Health Behavior and Education

1115   Reasons Why Patients Leave Against Medical Advice (AMA) Following an Asthma Hospitalization

R. Arora, I. Warrier, A. P. Baptist; Wayne State University, Detroit, MI.

1116   Asthma Controller Awareness, Knowledge, Health Beliefs and Behaviors

M. Tsoukleris ^1,2, V. Hsu¹, C. L. Vibbert², M. E. Bollinger², A. M. Butz³; ¹University of Maryland School of Pharmacy, Baltimore, MD, ²University of Maryland School of Medicine, Baltimore, MD, ³The Johns Hopkins University School of Medicine, Baltimore, MD.

1117   Curriculum Development for the Theory-driven, Research-guided, School-based Staying Healthy-Asthma Responsible & Prepared Education and Counseling Program

E. K. Kintner, M. Clary, G. D. Cook; Michigan State University, East Lansing, MI.

1118   Adolescents' Disease Empowerment and Persistency Technology (ADEPT) Increases Asthma Knowledge among Inner City African American Teenagers Using MP3 Players

G. S. Mosnaim ¹, C. Rhoads², M. Cohen³; ¹Rush University Medical Center, Chicago, IL, ²Northwestern University, Chicago, IL, 367Khz Inc., Chicago, IL.

1119   Educational Asthma Summer Camp Including Exercise Challenge Test Improved Adherence

N. Kojima ¹, Y. Takeda², M. Akashi¹, A. Akasawa¹; ¹National Center for Child Health and Devepolment, Tokyo, JAPAN, ²Division of Health and Welfare, Kita Ward, Tokyo, JAPAN.

Poster Session

5209

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Signaling

1120   Modulation of Nitric Oxide (NO) production by Histamine Receptor Antagonists

R. A. Khanferyan ¹, D. V. Lesik¹, L. M. DuBuske²; ¹Kuban State Medical University, Krasnodar, RUSSIAN FEDERATION, ²Immunology Research Institute of New England, Gardner, MA.

1121   Activation of Mast Cells Induces PKC-dependent Phosphorylation of Serine-273 of the LILRB4 Inhibitory Receptor that is Self-Regulated

D. I. Hong, T. R. Murphy, K. F. Austen, H. R. Katz; Brigham & Women's Hospital, Boston, MA.

1122   Neutralization of CD86 Reduced the Th2 Immune Response in Murine Allergic Aspergillosis

C. Barrios ¹, B. Johnson¹, J. Fink¹, V. Kurup^1,2; ¹Medical College Of Wisconsin, Milwaukee, WI, ²V A Medical Center, Milwaukee, WI.

1123   Paracrine Involvement of LTD4-induced TGFbeta1 Secretion by Epithelial Cells in Bronchial Smooth Muscle Cell proliferation

Y. Bossé, C. Thompson, S. McMahon, C. M. Dubois, J. Stankova, M. Rola-Pleszczynski; Université de Sherbrooke, Sherbrooke, PQ, CANADA.

1124   Parthenolide, a Sesquiterpene Lactone From the Medicinal Plant, Feverfew, Inhibits IκB kinase, Nuclear Factor-κB activation and Inflammatory response in CF cell lines and Mice

A. Saadane ¹, S. Masters¹, J. DiDonato², J. Li¹, M. Berger¹; ¹CWRU, Cleveland, OH, ²Lerner Research Institute, Cleveland Clinic, Cleveland, OH.

1125   Constitutive Association of Lyn A and B Kinases with the High Affinity IgE Receptor (FceRI) Positively Regulates Mast Cell Secretion

S. J. Killedar, S. Gibbons, Jr., H. Chang, E. Lin, B. M. Vonakis; Johns Hopkins Asthma and Allergy Center, Baltimore, MD.

1126   Activation of Effector Memory CD8⁺ T Cells Following Ligation of BLT1 by Leukotriene B4

H. Ohnishi¹, N. Miyahara¹, C. H. Swasey¹, K. Takeda¹, A. Dakhama¹, J. Domenico¹, J. J. Lucas¹, S. Mathis², B. Haribabu², E. W. Gelfand ¹; ¹National Jewish Medical and Research Center, Denver, CO, ²James Graham Brown Cancer Center, Louisville, KY.

1127   MK2 Controls the Level of Negative Feedback in the NFκB Pathway and is Essential for Endothelial Permeability and Airway Inflammation

M. M. Gorska ¹, Q. Liang¹, S. J. Stafford², N. Goplen¹, N. Dharajiya², L. Guo¹, S. Sur², M. Gaestel³, R. Alam¹; ¹National Jewish Medical and Research Center, Denver, CO, ²University of Texas Medical Branch, Galveston, TX, ³Hannover Medical School, Hannover, GERMANY.

1128   Interleukin-4 Receptor Alpha Chain ITIM Motif Mutant Mice Potentiate Stat6 Activation and IgE Production

R. Tachdjian, N. Truong, T. A. Chatila; UCLA School of Medicine, Los Angeles, CA.

1129   Signaling Interactions Between IL-4 or IL-13 and Leukotrienes in Allergic Inflammation

M. O. Daines, P. A. Zornes, G. K. Khurana Hershey; Cincinnati Children's Hospital, Cincinnati, OH.

1130   Inhibitory Functions of Siglec-8 in Transfected RBL-2H3 Cells

H. Lee ¹, S. Ryu², S. A. Hudson², C. Bikel², O. H. Choi², B. S. Bochner²; ¹Kwandong University College of Medicine, Goyang, REPUBLIC OF KOREA, ²Johns Hopkins University School of Medicine, Baltimore, MD.

1131   Lipoxin A4 Antagonizes Granulocyte and Macrophage Activation Evoked by Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) by Inhibition of Protein Phosphorylation

V. Starosta, K. Pazdrak, A. Kurosky; UTMB, Galveston, TX.

1132   Surfactant Protein D (SP-D) Inhibits TNF-α Production In CpG-induced Alveolar Macrophages Via Irak-1 Inactivation

K. Yeh ^1,1, L. Wang², C. Liu³, W. Chang¹, J. Wang¹, C. Shieh¹; ¹Dept of Microbiology&Immumology, College of Medicine, National Cheng Kung University, Tainan, TAIWAN, ²Dept of Biochemistry, College of Medicine, National Cheng Kung University, Tainan, TAIWAN, ³Institude of Basic Medical Sciences, College of Medicine, National Cheng Kung University, Tainan, TAIWAN.

1133   A Phospho-site Screen Identifies Baseline Activation of PKR As a Survival-limiting Factor For Eosinophils

N. P. Goplen ¹, S. J. Stafford², Q. Liang¹, M. Gorska¹, S. Rozario¹, R. Alam¹; ¹National Jewish Medical Research Center, Denver, CO, ²University of Texas Medical Branch, Galveston, TX.

1134   Effect of Chitinase on Il-8 Gene Expression in Human Respiratory Epithelial Cells

J. Y. Hong ¹, K. E. Lee², K. W. Kim¹, E. S. Kim¹, J. Y. Park¹, M. H. Sohn¹, K. E. Kim¹; ¹Department of Pediatrics, Severance Children's Hospital,Yonsei University College of Medicine Brain Korea 21 Project for Medical Science, Yonsei University, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, Severance Children's Hospital,Yonsei University College of Medicine Brain Korea 21 Project for Medical Science, Yonsei University, Seoul, REPUBLIC OF KOREA.

1135   Scavenging of Reactive Oxidative Species (ROS) Generated by Pollen NADPH Oxidases Inhibits Th2 and Th17 Cytokine Production from Johnson Grass (JG)Sensitized Human Peripheral Blood Mononuclear Cells (PBMCs)

M. C. Saavedra, N. G. Dharajiya, D. R. Redding, I. Boldogh, C. Y. Lee, S. Sur; UTMB, Galveston, TX.

1136   Multiple Granulocyte Priming Phenotypes In Peripheral Blood Of Allergic Asthmatics

L. Koenderman ¹, W. Ten Hove², B. Luijk¹, B. Leufkens², J. Lammers¹, J. Raaijmakers², M. Bracke²; ¹University Medical Center Utrecht, Utrecht, THE NETHERLANDS, ²Utrecht Institute for Pharmaceutical Sciences, Utrecht, THE NETHERLANDS.

1137   The Effect of Daily Apolipoprotein A-I Mimetic Therapy on Pro-Inflammatory High Density Lipoprotein in a Murine Model of Asthma

S. D. Nandedkar ¹, K. S. Konduri¹, J. Wang¹, H. Xu¹, Y. Shi¹, D. A. Rickaby¹, N. Duzgunes², K. A. Pritchard¹; ¹Medical college of Wisconsin,Children's Research Institute, and Zablocki VA Medical Center, Milwaukee, WI, ²University of Pacific School of Dentistry, San Franscisco, CA.

1138   NADPH Oxidases in Johnson Grass Extract (JGE) Induce Intracellular ROS (iROS) in Bronchial Epithelial Cells

D. R. Redding, M. C. Saavedra, J. G. Patel, N. Dharajiya, I. Boldogh, S. Sur; University of Texas Medical Branch at Galveston, Galveston, TX.

1139   Leukocyte and Eosinophil Progenitor Cells in Peripheral Blood Correlate with Asthma Severity

J. S. Makowska, J. Grzegorczyk, B. Bienkiewicz, M. Cieslak, M. L. Kowalski; Medical University of Lodz, Poland, Lodz, POLAND.

1140   Exhaled Bronchial Nitric Oxide in Chronic Nasal Inflammation

M. F. Kramer ¹, H. Dressel², A. Bihler², F. Jund¹, D. de la Motte², R. Joerres², D. Nowak²; ¹Oto-Rhino-Laryngology, Head and Neck Surgery; Ludwig-Maximilians-University, Munich, GERMANY, ²Institute and Outpatient Clinic for Occupational and Environmental Medicine; Ludwig-Maximilians-University, Munich, GERMANY.

1141   Increased Leukotriene B4 In Exhaled Breath Condensate From Asthmatic Children

J. Y. Park ¹, K. W. Kim¹, E. S. Kim¹, J. Y. Hong¹, C. H. Kim², M. H. Sohn¹, K. E. Kim¹; ¹Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, Kwandong University College of Medicine, Goyang, REPUBLIC OF KOREA.

1142   A Novel Mouse Model of Whole Pollen Grain Induced Rhinitis

J. Brimnes, J. Kildsgaard, H. Jacobi, K. Lund; ALK-Abello, Hoersholm, DENMARK.

1143   Effect of Forced Swimming Exercise Stress on Allergic Pulmonary Inflammation in Mice

G. P. Shome, L. E. Hulbert, N. Krebs, M. A. Sutherland, M. Watchell, J. J. McGlone; Texas Tech University, Lubbock, TX.

1144   Formaldehyde Exposure Induces Airway Inflammation Via Regulation Of The Production Of Eotaxin And Reactive Oxygen Species

H. Yoon; Chonnam national university, Gwang-ju, REPUBLIC OF KOREA.

1145   Lack of Filaggrin Expression in the Human Bronchial Mucosa

T. H. Lee, S. Ying, Q. Meng, C. J. Corrigan; King's College London, London, UNITED KINGDOM.

1146   Age-Dependent Ontogeny of TLR4 Expression on Peripheral Lymphocytes and their Modulation by Interleukin-4

J. An, A. Banville-Langelier, P. O. Fiset, D. Prefontaine, M. B. Mazer, J. Guay, O. Hajoui, Q. Hamid, B. D. Mazer; Meakins Christie Laboratories, Montreal, PQ, CANADA.

Poster Sessions

5210

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

MAAI Topics

1147   Effect of Fluticasone on Airway Smooth Muscle (ASM) in Mice Treated with IL-13

J. Evans, P. R. Gendapodi, P. Abel, F. Romero, R. G. Townley; Creighton University, Omaha, NE.

1148   Different Roles of Aspirin during Antigen Challenge in Murine Model of Asthma

S. Kim ¹, Y. Kim², J. Lee¹, T. Kim¹, J. Sohn¹, H. Yoon¹, D. Shin¹, S. Park¹, S. Chang³, D. Choi⁴; ¹Hanyang University College of Medicine, Seoul, REPUBLIC OF KOREA, ²Postech Biotech Center, Pohang University of Science and Technology, Pohang, REPUBLIC OF KOREA, ³Sungae Hospital, Seoul, REPUBLIC OF KOREA, ⁴Sungkyunkwan University School of Medicine, Seoul, REPUBLIC OF KOREA.

1149   Ngf (Nerve Growth Factor) Regulates Collagen Deposition Independent Of Tgf-β

A. Kilic, S. Sonar, D. Schwinge, A. Yildirim, S. Achenbach, H. Fehrenbach, A. Nockher, H. Renz; Hospital of the Philipps University, Marburg, GERMANY.

1150   Role of Endogenous Estrogen in Regulating Airway Hyperresponsiveness Induced by Allergen Inhalation Without Adjuvant

S. Matsubara, C. H. Swasey, A. Dakhama, J. E. Loader, H. Ohnishi, A. Joetham, A. Balhorn, N. Miyahara, K. Takeda, E. W. Gelfand; National Jewish Medical and Research Center, Denver, CO.

1151   Increase of CD25 and RLA II Positive-Cells Population in Perivascular Infiltrate in Lungs from Ovalbumin (OVA) Sensitized and Challenged Rabbits

M. A. Vinuesa, Sr., G. Fontanella, Sr., N. Bassan, Sr., O. Soldano, Sr., S. Chaparro, Sr., N. Caviglia, Sr.; Facultad de Ciencia Medicas, Rosario, ARGENTINA.

1152   Grass Hypersensitivity Causing Bronchopulmonary Obstruction In A Patient With Cystic Fibrosis

L. Ree-Kim, J. El-Dahr; Tulane University Health Sciences Center, New Orleans, LA.

1153   Effect of Fluticasone and/or β-agonists on Airway Hyperresponsiveness (AHR) In Mice Either Sensitized to Allergen or Pre-treated with IL-13

R. G. Townley, P. R. Gendapodi, J. Evans, F. Romero; Creighton University, Omaha, NE.

1154   Type-I Allergic Reaction In Recently Diagnosed Untreated Pulmonary Tuberculosis

H. M. Elboshy, A. M. Nafei, E. N. Ali, A. I. Ali, T. A. Attia, M. S. Abdalla, E. E. Fouda; Al-Azhar University Allergy & Immunology Center, Cairo, EGYPT.

1155   Analysis of a LAM-derived Cell Transcriptome Identifies Similarity to Other Pulmonary Diseases

T. J. Whitney ¹, M. Brandon¹, L. Ma², B. Camoretti-Mercado²; ¹Idaho State University, Pocatello, ID, ²University of Chicago, Chicago, IL.

1156   Nasal Fibroblasts Derived from Allergic Patients Retain Their Typical Gene Expression Profile In Culture

M. Yoshikawa ¹, T. Yoshimura¹, N. Okada², H. Saito², H. Moriyama¹; ¹Department of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, JAPAN, ²Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN.

1157   Micro Flora Associated Characteristics and Changes in Allergic Sensitization During the First Four Years of Life

A. Sandin ¹, E. Norin², B. Björkstén³, L. Bråbäck⁴; ¹Department of Clinical Science, Paediatrics, Umeå, SWEDEN, ²Department of Cellular and Microbial Biology, Division of Microbial Ecology, Karolinska Institute, Stockholm, SWEDEN, ³The National Institute of Environmental Medicin, Division of Physiology, Karolinska Institute, Stockholm, SWEDEN, ⁴Mid-Sweden Research and Development Center, Sundsvall Hospital, Sundsvall, SWEDEN.

1158   Modulation of Effects of Albuterol Enantiomers on IL-6 Release in Human Airway Smooth Muscle Cells as a Function of Cell Stimulation

E. A. Duru, J. L. Parks, IV, W. J. Calhoun, B. T. Ameredes; Unuversity of Texas Medical Branch, Galveston, TX.

1159   Regulation of Dendritic Cell Function by Surfactant Protein D

S. Kierstein, L. Hortobagyi, K. Krytska, A. Haczku; University PA School Medicine, Philadelphia, PA.

1160   Glucocorticoid Induced Leucine Zipper Mediates the Anti-Inflammatory Effects of Dexamethasone in Airway Epithelial Cells

J. Eddleston ^1,2, J. Herschbach², A. L. Wagelie-Steffen¹, S. C. Christiansen^1,3, B. L. Zuraw^1,2; ¹UCSD, La Jolla, CA, ²VMRF, San Diego, CA, ³Kaiser Permanente, San Diego, CA.

1161   Analysis of Chemokine and Cytokine Production by a Human Alveolar Epithelial Cell Line in Response to Pollen Surface Proteins

J. M. Ward; The University of Chicago, Chicago, IL.

1162   Oral Sulforaphane Induces Antioxidant Phase II Enzymes in the Human Airway

M. A. Riedl, A. Saxon, D. Diaz-Sanchez; UCLA - David Geffen School of Medicine, Los Angeles, CA.

1163   Increased Plasma Levels Of Vascular Endothelial Growth Factor And Plasminogen Activator Inhibitor-1 In Children With Frequent Asthma Exacerbations

H. Chung, S. Kim, S. Kim; School of Medicine, Catholic University of Taegu, Taegu, REPUBLIC OF KOREA.

1164   Identification of Allergen-Susceptibility Genes Using Recombinant Inbred Mouse Model of Allergic Asthma

D. N. Grigoryev ¹, E. P. Hoffman², M. Wills-Karp³, K. C. Barnes¹; ¹Johns Hopkins University, School of Medicine, Baltimore, MD, ²Children's National Medical Center, Washington, DC, ³Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

1165   Effect Of ISS And TGF-β1 On MLg Lung Fibroblast Proliferation In Vitro

S. Deane, M. Miller, J. Cho, D. H. Broide; UC San Diego, San Diego, CA.

1166   A Novel Inducible Transgenic Histamine Releasing Factor Construct

L. Xie, Z. Zhu, S. M. MacDonald; JHUSM, Baltimore, MD.

1167   A Neuroactive Steroid Inhibits Guinea-pig Airway Sensory Nerves via Maxi-K⁺ Channels Activation

S. Yoshihara ¹, H. Morimoto², M. Ohori², Y. Yamada¹, T. Abe¹, O. Arisaka¹; ¹Dokkyo University School of Medicine, Mibu,Tochigi, JAPAN, ²Department of Pharmacology, Medical Biology Research Laboratories,Fujisawa Pharmaceutical Co., Ltd., Osaka, JAPAN.

1168   The effect of Kawasaki Disease on Allergy in childhood

W. K. Liew ¹, T. C. W. Lim², H. V. Bever², S. C. Quek², T. H. Tan¹, K. Y. Wong¹; ¹Kerdang Kerbau Hospital, Singapore, SINGAPORE, ²National University Hospital, Singapore, SINGAPORE.

1169   Relation of Elevated Plasma Complement Split Product Levels to Their Peripheral Blood Leukocyte Receptors and Asthma Severity

H. Solomon, I. Kalampokis, D. Dure, S. Chice, M. Nowakowski, H. G. Durkin, R. Joks; Center for Allergy and Asthma Research, SUNY Downstate, Brooklyn, NY.

1170   Ligands for Siglec-8 and Siglec-F: Binding Characteristics and Tissue Distribution

J. P. Guo ¹, A. C. Myers¹, O. Choi¹, H. S. Lee¹, Z. Zhu¹, S. A. Hudson¹, M. Brummet¹, N. V. Bovin², P. R. Crocker³, B. S. Bochner¹; ¹Johns Hopkins Asthma and Allergy Center, Baltimore, MD, ²Russian Academy of Sciences, Moscow, RUSSIAN FEDERATION, ³University of Dundee, Dundee, UNITED KINGDOM.

1171   Ngf (nerve Growth Factor): A Key Player In Events Ensuing Lung Epithelium Injury And Repair

S. Sonar, D. Schwinge, A. Kilic, A. Yildirim, S. Achenbach, H. Fehrenbach, A. Nockher, H. Renz; Hospital of the Philipps University, Marburg, GERMANY.

1172   Association Between Thromboxane A2 Receptor Gene Polymorphisms (+924T>C, +795T>C) and Asthma in Korean Children

J. Kim ¹, H. Kim², M. Kang³, S. Lee⁴, B. Kim⁵, S. Jang³, S. Hong³; ¹Ulsan University Hospital, Ulsan, REPUBLIC OF KOREA, ²Inje University Sanggye Paik Hospital, Seoul, REPUBLIC OF KOREA, ³Asan Medical Center, Seoul, REPUBLIC OF KOREA, ⁴Hallym University College of Medicine, Hangang Sacred Heart Hospital, Seoul, REPUBLIC OF KOREA, ⁵Gangneung Asan Hospital, Gangneung, REPUBLIC OF KOREA.

1173   Is CRP a Useful Marker for Inflammation in Different Forms of Rhinitis?

A. Baccιoglu, F. Kalpaklioglu; Kirikkale University Faculty of Medicine, Kirikkale, TURKEY.

1174   Expression of the Novel ER-α36 Variant of Estrogen Receptors in Murine Lung: Effects of Antigen Sensitization

S. Jia, X. Zhang, Z. Wang, T. B. Casale; Creighton University, Omaha, NE.

1175   Airway Fibroblasts Isolated from Mouse Model of Allergic Asthma Display Distinct Cellular and Phenotypic Characteristics as Compared to Normal Fibroblasts

A. I. Berro ¹, H. Sugiura², X. Liu², F. Duan², S. Kawasaki², S. Togo², K. Kamio², X. Q. Wang², L. Mao³, Y. Ahn², R. F. Ertl², T. B. Casale¹, S. I. Rennard²; ¹Creighton University, Omaha, NE, ²University of Nebraska Medical Center, Omaha, NE, ³Third Hospital of Peking University, Beijing, CHINA.

1176   Effect Of Cetirizine On Early- And Late-phase Airway Responses In A Brown Norway Rat Model Of Allergic Asthma

X. Zhang, P. Siegel; Centers for Disease Control and Prevention, Morgantown, WV.

1177   Nor-nordihydroguaiaretic Acid (NDHGA) Ameliorates C5a-Induced Acute Peritonitis

P. N. Pushparaj ¹, S. D. Kumar¹, J. J. Aarthi²; ¹National University of Singapore, Singapore, SINGAPORE, ²Singapore General Hospital, Singapore, SINGAPORE.

1178   Biochemical Efficacy and Tolerability of a New Augmentation Preparation in Two Patients with MMALTONZ Alpha1-Antitrypsin Deficiency

J. M. Stocks ¹, M. Brantly²; ¹The University of Texas Health Center at Tyler, Tyler, TX, ²University of Florida College of Medicine, Gainesville, FL.

Poster Sessions

5211

Tuesday, February 27, 2007

9:45 AM - 10:45 AM

Mechanisms and Treatment of Rhinitis, Sinusitis, Otitis and Allergic Conjunctivitis

1179   Fungal Etiology of Chronic Sinusitis: Knowledge and Attitudes Survey in the US and Europe

A. Stergious ¹, R. Casciano¹, L. Katz¹, M. Memran², J. Willet¹; ¹Accentia Biopharmaceuticals, New York City, NY, ²Analytica International, New York City, NY.

1180   Differences in Treatment Practices of Chronic Sinusitis in Europe and US

R. Casciano ¹, A. Stergious¹, L. Katz¹, M. Memran², J. Willet¹; ¹Accentia Biopharmaceuticals, New York City, NY, ²Analytica International, New York City, NY.

1181   Oral Itraconazole in the Treatment of Chronic Rhinosinusitis

A. Y. Kung, H. Kita, J. C. Guarderas, R. O. Gustafson, M. A. Park; Mayo Clinic, Rochester, MN.

1182   Aspirin Desensitization: The University Of Michigan Experience

T. A. Miller ^1,2, J. L. Baldwin¹; ¹University of Michigan, Ann Arbor, MI, ²Capital Allergy & Respiratory Disease Center, Sacramento, CA.

1183   Relationship Between IFN-γ Genotypes and the Development of Otitis Media (OM) During Respiratory Syncytial Virus (RSV) Infection in Young Children

J. M. Koehrsen, D. P. Skoner, D. A. Gentile, A. Patel, M. Varga, T. J. Schaffner, C. A. Schad; Allegheny General Hospital, Pittsburgh, PA.

1184   Inflammation And Remodelling Parameters In Induced Sputum Of Nonasthmatic Seasonal Allergic Rhinitis

A. B. Dursun ¹, G. Celik¹, M. Melli², Z. Misirligil¹; ¹Ankara University, School of Medicine, Department of Respiratory Medicine, Allergic Diseases Division, Ankara, TURKEY, ²Ankara University, School of Medicine, Department of Clinical Pharmacology, Ankara, TURKEY.

1185   Comparison of ICAM-1, HLA-DR, TLR2, and TNFR1 Expression in Response to Staphylococcus aureus and Pro-Inflammatory Cytokines between Primary Conjunctival Epithelial Cells and the Cell Line, IOBA-NHC

J. L. Stahl, E. B. Cook, N. P. Barney, F. M. Graziano; University of Wisconsin-Madison, Madison, WI.

1186   Effect of Treatment with Montelukast on Otitis Media (OM) in Children

D. A. Gentile, J. M. Koehrsen, D. P. Skoner, A. Patel, M. Varga, C. A. Schad, T. J. Schaffner; Allegheny General Hospital, Pittsburgh, PA.

1187   Knemometric Assessment of Short-Term Lower-Leg Growth in Children with Allergic Rhinitis (AR) treated with Fluticasone Furoate^∗ (FF) Nasal Spray

^∗USAN approved name

J. Gradman ¹, M. Caldwell², O. Wolthers¹; ¹Asthma and Allergy Clinic, Children's Clinic Randers, Randers, DENMARK, ²GlaxoSmithKline, Greenford, UNITED KINGDOM.

1188   Once-Daily Fluticasone Furoate^∗ Nasal Spray (FFNS) 110mcg Improves Quality of Life (QoL) in Subjects with Seasonal Allergic Rhinitis (SAR) during the ragweed season

^∗USAN approved name

J. Given ¹, T. Toler², A. Ellsworth², R. Stanford², E. Philpot²; ¹Allergy Respiratory & Sleep Center, Canton, OH, ²GlaxoSmithkline, RTP, NC.

1189   Once-daily Fluticasone Furoate^∗ Nasal Spray (FF) is Safe and Effective in The Long-term Treatment of Perennial Allergic Rhinitis (PAR) in Children Ages 2 to 11 Years

^∗USAN approved name

J. F. Maspero ¹, A. Rosenblut², A. Finn, Jr.³, J. Lim⁴, W. Wu⁴, M. Faris⁵, E. Philpot⁴; ¹Allergy and Clinical Immunology Buenos Aires University, Buenos Aires, ARGENTINA, ²Hospital Dr. Sotero del Rio, Santiago, CHILE, ³National Allergy, Asthma, Urticaria Center of Charleston, Charleston, SC, ⁴GlaxoSmithKline, RTP, NC, ⁵GlaxoSmithKline, Greenfort, UNITED KINGDOM.

1190   Once-daily Fluticasone Furoate^∗ Nasal Spray (FF) Provides 24-hour Symptom Relief In Subjects With Seasonal Allergic Rhinitis (SAR) Caused By Mountain Cedar Pollen

^∗USAN approved name

F. C. Hampel, Jr. ¹, R. Jacobs², B. Martin³, T. Toler⁴, A. Ellsworth⁴, E. Philpot⁴; ¹Central Texas Health Research, New Braunfels, TX, ²Biogenics Research Institute, San Antonio, TX, ³Southwest Allergy and Asthma Research, San Antonio, TX, ⁴GlaxoSmithKline, Research Triangle Park, NC.

1191   Lack of Effect on Hypothalamic-Pituitary-Adrenal (HPA) Axis Function by Once-daily Fluticasone Furoate^∗ Nasal Spray(FFNS) 110 mcg in Adolescents and Adults with Perennial Allergic Rhinitis (PAR)

^∗USAN approved name

D. Patel ¹, P. Ratner², D. Clements³, W. Wu³, M. Faris³, E. Philpot³; ¹Allied Research International Inc, Mississauga, ON, CANADA, ²Sylvana Research Associates, San Antonio, TX, ³GlaxoSmithKline, Research Triangle Park, NC.

1192   Effect Of Desloratadine On The Bronchial Reactivity During Allergen Provocation Tests In Rhinitics Allergic To Grass Pollen

A. Purohit ¹, C. Donnay¹, A. Casset¹, M. Kopferschmitt¹, I. Dreyfus², F. Sevenier³, F. de Blay¹; ¹Asthma and Allergy Division, Department of Chest Diseases, University Hospital Strasbourg, Strasbourg, FRANCE, ²Schering-Plough laboratories, Levallois-Perret, FRANCE, ³Fovea, Paris, FRANCE.

1193   Once-daily Fluticasone Furoate^∗ Nasal Spray (FF) Provides 24-hour Relief of the Nasal Symptoms of Seasonal Allergic Rhinitis (SAR) in Children ages 2-11 Years

^∗USAN approved name

E. O. Meltzer ¹, I. Tripathy², J. Lee³, J. Lim⁴, A. Ellsworth⁴, E. Philpot⁴; ¹University of California, San Diego, San Diego, CA, ²Clinical Research of Ozarks, Rolla, MO, ³Advance Care Research Center, Dallas, TX, ⁴GlaxoSmithKline, RTP, NC.

1194   Lack of Correlation Between Physical Exam(PE), Mini RQLQ (MRQLQ), and Nasal Peak Inspiratory Flow (nPIF) as Measures of Nasal Congestion in Obstructive Sleep Apnea (OSA) Patients With Rhinitis

M. R. Rupp, Jr. ¹, A. S. Baran², G. D. Marshall, Jr.²; ¹Allergy and Asthma Clinic of Southern New Mexico, Las Cruces, NM, ²University of Mississippi Medical Center, Jackson, MS.

1195   Videophone Technology, a Novel Measure of True Treatment Compliance in a 6-week Pediatric Safety Study of Fluticasone Furoate^∗ Nasal Spray

^∗USAN approved name

D. Clements, W. Wu, E. Philpot; GlaxoSmithKline, Research Triangle Park, NC.

1196   Positron Emission Tomography of the Airway Distribution of Intranasal Challenge Solutions

L. Conejero ¹, M. L. Soto¹, J. J. Vaquero¹, M. L. Baeza¹, E. Lage¹, I. Varela-Nieto², M. Desco¹, J. M. Zubeldia¹; ¹Hospital Gregorio Maranon, Madrid, SPAIN, ²Instituto Investigaciones Biomedicas Alberto Sols. CSIC-UAM, Madrid, SPAIN.

Oral Abstract Session

5601

Tuesday, February 27, 2007

2:00 PM - 3:15 PM

Pharmacotherapy of Asthma

1197   VEGF Receptor 2 (KDR) is Up-regulated in the Nasal Mucosa of Seasonal Allergic Rhinitics

A. Tarun¹, D. Shusterman ²; ¹Seattle Biomedical Research Institute, Seattle, WA, ²University of Washington, Seattle, WA.

1198   Andolast, a Novel Calcium-activated Potassium-channel Opener, Inhibits AMP and Exercise Induced Bronchoconstriction in Asthma

S. H. Arshad ¹, M. D'Amato², L. Rovati², S. T. Holgate¹; ¹University of Southampton, Southampton, UNITED KINGDOM, ²Rotta Research Laboratorium/Rottapharm, Monza, ITALY.

1199   Differential Contribution Of Cysteinyl Leukotriene Receptor Type 1 Gene In Patients With Aspirin Hypersensitivity

S. Kim ¹, E. Yang¹, J. Choi², H. Lee¹, C. Suh¹, D. Nahm¹, H. Park¹; ¹Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA, ²Bundang Jesaeng general Hospital, Seongnam, REPUBLIC OF KOREA.

1200   Modulation Of Cysteinyl Leukotriene (CysLT) Production And Responsiveness By Corticosteroids (CCS)

J. A. Negri, L. Borish, J. W. Steinke; University Of Virginia Health Systems, Charlottesville, VA.

1201   Exploring the Effect on Asthma Control of Omalizumab Reduction After 28 Weeks Treatment

R. Slavin ¹, P. Lowe², C. Ferioli², H. Fox³, L. Carpenter³, C. Martin³, W. Sallas⁴; ¹Saint Louis University School of Medicine, Saint Louis, MO, ²Novartis Pharmaceuticals AG, Basel, SWITZERLAND, ³Novartis Horsham Research Centre, Horsham, UNITED KINGDOM, ⁴Novartis Pharmaceuticals Corporation, East Hanover, NJ.

1202   Exploring the Relationship Between Asthma and Rhinitis Response Following Omalizumab Therapy: Patients who Achieve Greatest Benefit for their Asthma Experience Greatest Benefit for Rhinitis

L. Boulet ¹, Z. Panahloo², M. Blogg², G. Ayre²; ¹Institut de Cardiologie et de Pneumologie de l'Université Laval, Hoˆpital Laval, Sainte-Foy, PQ, CANADA, ²Novartis Horsham Research Centre, Horsham, UNITED KINGDOM.

Oral Abstract Session

5602

Tuesday, February 27, 2007

2:00 PM - 3:15 PM

T Regulatory Cells in Immunopathology

1203   CD4⁺CD25⁺ T cells Regulate TLR4 Signaling in Pulmonary Dendritic Cells

H. Chen, D. A. Piggott, L. Xu, K. Bottomly; Yale University, New Haven, CT.

1204   Th2 Inflammation reduces Toll-Like Receptor 4 Expression and Regulatory Functions of T Cells

D. Préfontaine, M. Mazer, A. Banville-Langelier, P. Fiset, B. D. Mazer, Q. Hamid; Meakins-Christie Laboratories, McGill University, Montreal, PQ, CANADA.

1205   TGF-beta Stimulated Human CD4+CD25-FOXP3- Cells Express FOXP3, But Lack Regulatory Function

D. Tran, E. M. Shevach; NIH/NIAID, Bethesda, MD.

1206   Suppression Induced By In Vitro Expanded Human Tregs Is Antigen-independent And Is Partly Abrogated By GITR Signalling

A. Domdey¹, A. H. Millner¹, K. Lund¹, I. Søndergaard², P. A. Würtzen ¹; ¹ALK-Abello, Hørsholm, DENMARK, ²BioCentrum-DTU, Technical University of Denmark, Lyngby, DENMARK.

1207   Kinetics of Gene Related to Anergy in Lymphocytes (grAIL) expression in CD4+ CD25+ T Regulatory Cells and Correlation with Suppression and T:APC Conjugate Formation

J. M. Schartner, A. Timmel, W. Simonson, M. Jennens-Clough, A. Huttenlocher, C. M. Seroogy; University of Wisconsin - Madison, Madison, WI.

1208   The Functional Insufficiency of Natural Regulatory T Cells in Allergic Asthma May Due to TNF Downregulation

Y. Lin ^1,2, J. Wang¹; ¹Dept of Ped, College of Medicine, National Cheng Kung University, Tainan, TAIWAN, ²Institute of Microbiology and Immunology, National Cheng Kung University, Tainan, TAIWAN.

Oral Abstract Session

5603

Tuesday, February 27, 2007

2:00 PM - 3:15 PM

Animal Allergens and Asthma

1209   Cat Ownership Is A Risk Factor For Developing Sensitization To Cat But Not Wheeze By Age 5 In A Low Income New York City Birth Cohort

M. S. Perzanowski ^1,2, G. L. Chew¹, A. Divjan¹, A. Johnson¹, K. Panjwani¹, B. J. Sheares¹, T. A. Platts-Mills³, F. P. Perera¹, R. L. Miller¹; ¹Columbia Children's Center for Environmental Health (CCCEH), New York, NY, ²Department of Environmental Health Sciences, Columbia University, New York, NY, ³Asthma and Allergic Diseases Center, University of Virginia, Charlottesville, VA.

1210   Is the Attenuation in Risk of Sensitisation and Wheezing observed at High Allergen Exposures due to a Modified Th Response?

M. G. Jones, J. Harris, W. Atkinson, P. Mills, S. A. Moffat, C. W. White, A. Newman Taylor, P. Cullinan; NHLI

1211   Immunomodulatory Effects of Allergen-specific Sublingual Immunotherapy in a Rat Model of Allergic Sensitization

L. A. Rosenthal ¹, X. Su¹, R. J. Szakaly¹, R. L. Sorkness^1,2; ¹University of Wisconsin School of Medicine and Public Health, Madison, WI, ²School of Pharmacy, University of Wisconsin-Madison, Madison, WI.

1212   Sensitization to Mouse Allergen and Asthma Morbidity in a Population of Boston Women

W. Phipatanakul ^1,2, A. A. Litonjua², T. A. E. Platts-Mills³, L. Naccara³, J. C. Celedon², H. Abdulkerim², S. T. Weiss², D. R. Gold²; ¹Children's Hospital, Boston, Harvard Medical School, Boston, MA, ²Channing Laboratory, Brigham and Women's Hospital, Boston, MA, ³University of Virginia, Charlottesville, VA.

1213   Changes in IgE and IgG Antibody Responses to Cat with Decreased Exposure to Cat Allergen

E. A. Erwin, S. M. Satinover, A. J. Reefer, J. A. Woodfolk, T. A. E. Platts-Mills; University VA, Charlottesville, VA.

1214   Dog Exposure at Birth through Age 3 Reduces the Risk of Asthma at Age 6

N. A. Hallett, K. A. Roberg, E. L. Anderson, L. E. P. Salazar, R. A. Grabher, D. F. DaSilva, J. D. Bufford, K. T. Sullivan Dillie, R. Gangnon, M. D. Evans, J. E. Gern, R. F. Lemanske, Jr.; University of Wisconsin School of Medicine and Public Health, Madison, WI.

Oral Abstract Session

5604

Tuesday, February 27, 2007

2:00 PM - 3:15 PM

Urticaria and Angiodema

1215   Over 10 Years Of Experience With The Use Of C1-inhibitor Concentrate In Hereditary Angioedema, In Retrospect

H. Farkas ¹, G. Temesszentandrási¹, B. Visy², G. Harmat², L. Varga¹, G. Füst¹, G. Széplaki¹, I. Karádi¹, B. Fekete¹, L. Jakab¹; ¹Semmelweis University, Budapest, HUNGARY, ²Madarász street Hospital of the Heim Pál' Pediatric Hospital, Budapest, HUNGARY.

1216   Functional Study Of Histamine N-methyltransferase (hnmt) Genetic Polymorphisms In Patients With Aspirin-intolerant Chronic Urticaria

Y. KANG ¹, S. Kim¹, Y. Ye¹, G. Hur¹, S. Lee², H. Lee¹, C. Suh¹, D. Nahm¹, H. Park¹; ¹Ajou university, Su-won, REPUBLIC OF KOREA, ²Dong-A University, Busan, REPUBLIC OF KOREA.

1217   Longitudinal Examination of Basophil Functional Phenotypes and Disease Activity in Chronic Idiopathic Urticaria (CIU)

L. M. Gober, P. M. Sterba, R. Baker, K. Vasagar, B. M. Vonakis, S. S. Saini; Johns Hopkins University, Baltimore, MD.

1218   Discovery of Ecallantide: A Potent and Selective Inhibitor of Plasma Kallikrein

R. Ladner, R. Kent, A. Ley, A. Nixon, D. Sexton; Dyax Corp., Cambridge, MA.

1219   Efficacy of Omalizumab for the Treatment of Allergic Urticaria and Angioedema

A. Rafi, L. Do, R. Mangat, S. Sender, R. M. Katz; Allergy Asthma Care Center of Santa Monica, Santa Monica, CA.

1220   Intraindividual And Interindividual Variations Of Symptoms In Patients With Hereditary Angioedema

E. Rusicke, I. Martinez-Saguer, E. Aygören-Pürsün, T. Klingebiel, W. Kreuz; JWG-University Hospital Frankfurt/Germany, Frankfurt/Main, GERMANY.

Oral Abstract Session

5605

Tuesday, February 27, 2007

2:00 PM - 3:15 PM

Mast Cells and Basophils

1221   Intestinal Expression of Interleukin 9 (IL-9) Induces Mast Cell-Mediated Intestinal Permeability

K. R. Groschwitz, E. E. Forbes, E. B. Brandt, R. Ahrens, F. D. Finkelman, P. Abonia, M. E. Rothenberg, S. P. Hogan; Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

1222   Treatment of RSV-Infected Newborn Mice With Anti-IgE Antibody Attenuates the Subsequent Enhancement of Airway Hyperresponsiveness on Re-Infection

A. Dakhama, Y. Lee, A. Balhorn, A. Joetham, E. W. Gelfand; National Jewish Medical and Research Center, Denver, CO.

1223   Human recombinant Histamine Releasing Factor (HrHRF) Induced Histamine Release (HR) is Associated with SHIP Knockdown (k/d) in both the Cultured Human Mast Cell (MC) and Basophil Models

J. M. Langdon, J. T. Schroeder, A. P. Bieneman, B. M. Vonakis, S. M. MacDonald; JHUSM, Baltimore, MD.

1224   The Immunosuppressant Drug FTY720 Inhibits Cytosolic Phospholipase A2 Independently of Sphingosine-1-Phosphate Receptors

S. Spiegel, S. Payne, C. Oskeritzian, S. Milstien; VCU School of Medicine, Richmond, VA.

1225   Activation of Protein Kinase D1 (PKD1) in Mast Cells by TLR, Kit, and FcepsilonRI ligands

T. R. Murphy, H. R. Katz; Harvard Med. Sch./Brigham & Women's Hosp., Boston, MA.

1226   CysLT2 Receptors Negatively Regulate CysLT1 Receptor Functions on Mast Cells Through Heterodimerization

J. A. Boyce, Y. Jiang; Brigham and Women's Hospital, Boston, MA.

Oral Abstract Session

5606

Tuesday, February 27, 2007

2:00 PM - 3:15 PM

Mechanisms of Allergic and Non Allergic Rhinitis

1227   The Ability of the Nose to Warm and Humidify Inspired Air is Heritable

J. Pinto, A. Sahin-Yilmaz, F. Baroody, M. deTineo, S. Elwany, C. Ober, R. M. Naclerio; The University of Chicago, Chicago, IL.

1228   Positive Nasal Allergen Provocation Test and Nasal Specific-IgE to Grass Pollen in Patients with Idiopathic Rhinitis

C. Rondon ¹, J. J. Romero¹, S. Lopez², R. R-Pena², J. L. Rodriguez-Bada², P. Chaves², I. Doña¹, M. Blanca¹; ¹Allergy Service, Carlos Haya Hospital, Málaga, SPAIN, ²Research Laboratory, Fundacion IMABIS-Carlos Haya Hospital, Málaga, SPAIN.

1229   Importance of Both Allergen-Specific (ANR) and Non-Specific Nasal Reactivity (NNR) in the Development of Early- and Late-Phase Nasal Responses

S. Miyahara, N. Miyahara, S. Matsubara, A. Joetham, E. W. Gelfand; National Jewish Medical and Research Center, Denver, CO.

1230   Effect of Montelukast on Nasal Secretion Weights During Naturally Acquired vURIs in Adults

D. P. Skoner, D. A. Gentile, J. M. Koehrsen, A. Patel, M. Varga, T. J. Schaffner, C. A. Schad; Allegheny General Hospital, Pittsburgh, PA.

1231   Influence of Allergen Immunotherapy on Substance P Release by Nasal Challenge of Grass Pollen Sensitized Allergic Rhinitis Patients

R. Gawlik ¹, B. Jawor¹, B. Rogala¹, L. M. DuBuske²; ¹Silesian University School of Medicine, Zabrze, POLAND, ²Immunology Research Institute of New England, Gardner, MA.