Skip to main content
Elsevier - PMC COVID-19 Collection logoLink to Elsevier - PMC COVID-19 Collection
. 2016 Mar 3;137(3):666. doi: 10.1016/j.jaci.2016.01.003

The contributions of allergic sensitization and respiratory pathogens to asthma inception

PMCID: PMC7133181

Instructions for category 1 Continuing Medical Education credit

The American Academy of Allergy, Asthma & Immunology is accredited as a provider of Continuing Medical Education (CME) by the Accreditation Council for Continuing Medical Education.

  • Test ID no.: mai00289

  • Contact hours: 1.0

  • Expiration date: February 28, 2017

Category 1 credit can be earned by reading the text material and taking this CME examination online. For complete instructions, visit the Journal's Web site at www.jacionline.org.

The Editors thank the University of South Florida Morsani College of Medicine Allergy/Immunology training program for developing this CME examination. The individuals who contributed to its preparation were Jennifer Fergeson, DO, Adeeb Bulkhi, MD, Andrew Cooke, MD, Chen Hsing Lin, MD, Sultan Alandijani, MD, and Peter Ricketti, DO, under the direction of Richard F. Lockey, MD.

The CME exam authors disclosed the following relationships: The exam authors disclosed no relevant financial relationships.

Learning objectives: “The contributions of allergic sensitization and respiratory pathogens to asthma inception”

  • 1.

    To understand that exposure to viral and bacterial pathogens is associated with recurrent wheezing and increased asthma risk in preschool-aged children.

  • 2.

    To determine the population at risk of developing asthma during childhood.

  • 3.

    To assess the effect of respiratory syncytial virus (RSV) infections on the future risk for asthma, and identify which patients would benefit from RSV prophylaxis.

  • 4.

    To understand the mechanisms of allergy-virus interactions and the association with allergic inflammation and asthma.

CME items

Question 1. Which humanized IgG mAb reduces the incidence of RSV infections in preterm infants?

  • A.

    mepolizumab

  • B.

    omalizumab

  • C.

    reslizumab

  • D.

    palivizumab

Question 2. Colonization with which of the following respiratory bacterial pathogens is associated with an increased risk for recurrent wheeze and early childhood asthma?

  • A.

    Neisseria meningitides, Streptococcus pneumoniae, and Haemophilus influenzae

  • B.

    S pneumoniae, Moraxella catarrhalis, and H influenzae

  • C.

    S pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa

  • D.

    Stenotrophomonas maltophilia, Burkholderia cepacia, and Candida albicans

Question 3. Which 2 viruses are most frequently associated with wheezing illnesses?

  • A.

    RSV and rhinovirus

  • B.

    metapneumovirus and coronavirus

  • C.

    parainfluenza virus and bocavirus

  • D.

    adenovirus and coronavirus

Question 4. Early administration with which antibiotic reduces the risk of progression to severe lower respiratory illness?

  • A.

    amoxicillin

  • B.

    amoxicillin/clavulanic acid

  • C.

    azithromycin

  • D.

    cefuroxime

Question 5. Intermediate- and late-onset wheezing are linked to which interleukin polymorphism?

  • A.

    IL-33

  • B.

    IL-4

  • C.

    IL-5

  • D.

    IL-13


Articles from The Journal of Allergy and Clinical Immunology are provided here courtesy of Elsevier

RESOURCES