Scientific Abstract Sessions

Poster Session

2201

Saturday, March 04, 2006

9:45 am to 10:45 am

Diagnosis and Epidemiology of Asthma

1   Characteristics of Pediatric Asthma Patients with Bronchodilator Irreversible Airflow Obstruction (AO)

G. Chiang, R. C. Strunk, L. B. Bacharier; Pediatrics, Washington University/St. Louis Children's Hospital, St. Louis, MO.

2   Epidemiological Study on Allergy and Asthma Phenotypes: Sub-clinical and Severe Asthma

C. D'Ambrosio ¹, P. Pierimarchi², M. Bresciani¹, C. Parisi¹, D. Spina¹, A. Torre², M. Turbati³, G. Rasi², S. Bonini^1,2; ¹IRCCS San Raffaele, Roma, ITALY, ²INMM-CNR, Roma, ITALY, ³ASSILT, Roma, ITALY.

3   Declines in Daily Digital Measures of FEV1 and Peak Flow Correspond with Albuterol Usage in Adults, but not in Children

K. D. Carel ^1,2, N. Rabinovitch^1,2, M. Strand³, M. Gleason¹, J. R. Mault⁴, A. H. Liu^1,2; ¹Pediatrics, National Jewish Medical and Research Center, Denver, CO, ²Pediatrics, University of Colorado School of Medicine, Denver, CO, ³Biostatistics, National Jewish Medical and Research Center, Denver, CO, ⁴MicroLife USA, Dunedin, FL.

4   The Effect of Vascular Endothelial Growth Factor on the Bronchial Hyper-Responsiveness in Children Asthma Patients

H. Kim ¹, J. Choung²; ¹Pediatrics, Korea University Hospital, Ansan, REPUBLIC OF KOREA, ²Pediatrics, Korea University Hospital, Seoul, REPUBLIC OF KOREA.

5   Relationship between Physician Diagnosed Asthma, eNO, and Measures of Airway Hyperresponsivenes

F. A. Romero, D. L. Waggoner, D. T. Chiang, J. Clark, R. J. Hopp, R. G. Townley, T. B. Casale; Department of Medicine: Division of Allergy and Immunology, Creighton University, Omaha, NE.

6   Bronchodilatory Response Achieved With Foradil Compared To Regularly Dosed Albuterol In Older Asthmatics

U. Yegen¹, D. Till², G. P. Geba ¹; ¹USCDMA, Novartis Pharmaceuticals Corp., E Hanover, NJ, ²Novartis Horsham Research Centre, Novartis Pharmaceuticals Corp., Horsham, UNITED KINGDOM.

7   Is Wheezing the Best Endpoint for Bronchial Challenges in Young Children?

L. Stewart, C. Mjaanes, M. Gleason, R. Covar, J. Spahn; Pediatrics, National Jewish Medical and Research Center, Denver, CO.

8   Percentage Fall in FVC at the Methacholine PC₂₀ (DFVC) in Cough-Variant Asthma and Classic Asthma

Y. Yoo ¹, J. Yu², D. K. Kim², S. H. Choi², Y. Y. Koh²; ¹Department of Pediatrics, Korea University Anam Hospital, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, Seoul National University Hospital, Seoul, REPUBLIC OF KOREA.

9   Misdiagnosis of Exercise Induced Asthma in Two Patients Years After Surgical Repair of Congenital Anomalies

Y. K. Persaud ¹, C. Lamm², B. Silverman¹, A. T. Schneider¹; ¹Allergy and Immunology, Long Island College Hospital, Brooklyn, NY, ²Allergy and Immunology, Mount Sinai Hospital, New York, NY.

10   ROC Curve Analysis of Skin Testing and Specific IgE Antibodies Values to Predict Clinical Allergy to Alternaria in Asthmatic Subjects

E. Bevilacqua, N. Fernández, C. Fernández, M. Garcimartin, S. Romero, A. Gomez, R. Vives; Servicio de alergia, HOSPITAL 12 DE OCTUBRE, MADRID, SPAIN.

11   Versican is Required for Hyaluronan (HA) Dependant Poly I:C Stimulated Leukocyte Binding to Human Lung Fibroblasts (HLF)

L. C. Altman ^1,2, S. Perigo², T. Wilkinson², P. Johnson², T. N. Wight^3,2; ¹Allergy, University of Washington School of Medicine, Seattle, WA, ²Benaroya Research Institute, Seattle, WA, ³University of Washington, Seattle, WA.

12   Utilisation of an Environmental Challenge Chamber (ECC) to Explore Allergen Induced Bronchial Hyperresponsiveness (BHR) in Mild Asthmatic Patients with Co-morbid Rhinitis

N. Krug ¹, J. M. Hohlfeld¹, A. Bruns¹, P. Russell², A. Weeks², M. Larbig¹, R. D. Murdoch²; ¹Fraunhofer ITEM, Hannover, GERMANY, ²GSK, Stevenage, UNITED KINGDOM.

13   Exercise-Induced Bronchospasm (EIB) in Obese and Non-Obese Adolescents

W. A. Lopes¹, N. Leite², G. C. Santos², A. L. Prestes², V. F. Dressler², N. A. Rosario ²; ¹Department of Physical Education, University of Parana, Curitiba, BRAZIL, ²Department of Pediatrics, University of Parana, Curitiba, BRAZIL.

14   Lung Function in Children with Stable, Controlled Asthma: A Critical Look at Inclusion Criteria for Clinical Trials in Childhood Asthma

A. Baatenburg de Jong, R. J. Roorda, P. L. P. Brand; Pediatrics, Princess Amalia Children's Clinic, Zwolle, THE NETHERLANDS.

15   Impaired Bronchodilatory Effect of Deep Inspiration With Increased Asthma Severity

S. Soresi ¹, N. Scichilone², A. Togias¹, V. Bellia²; ¹Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD, ²Cattedra di Malattie dell'Apparato Respiratorio, Istituto di Medicina Generale e Pneumologia,Universita’ degli Studi di Palermo, Palermo, ITALY.

16   Comparison of Asthma and Allergy Symptoms in Recreational Roadrunners with Olympic Athletes

C. C. RANDOLPH ¹, D. Bangalore²; ¹ALLERGY, YALE, WATERBURY, CT, ²Medicine /Information Services, Yale Affiliate Waterbury Hospital, WATERBURY, CT.

17   Underlying Aspiration Exacerbating Asthma in a Boy Treated for IgG Subclass Deficiency

P. Hemmers ¹, R. Giusti², B. Silverman¹, A. T. Schneider¹; ¹Allergy & Immunology, Long Island College Hospital, Brooklyn, NY, ²Pediatric Pulmonology, Long Island College Hospital, Brooklyn, NY.

18   Matrix Metalloproteinase-1 Polymorphism is Associated with Persistent Airway Obstruction in Chronic Stable Asthma in the Taiwanese Population

C. D. Huang, S. M. Lin, C. H. Wang, C. Y. Liu, H. C. Lin, H. P. Kuo; Department of Thoracic Medicine, Chang Gung Memorial Hospital, Taipei, Taiwan, TAIWAN REPUBLIC OF CHINA.

19   Risk Factors Associated with Repeat Emergency Department Visits for Children with Asthma in South Korea

Y. Rha ¹, S. Choi¹, S. Kim², D. Lee³, G. Park⁴, J. Park⁵; ¹Dept. of Pediatrics, Kyung Hee Medical Center, Seoul, REPUBLIC OF KOREA, ²Dept. of Pediatrics, St. Benedict Hospital, Busan, REPUBLIC OF KOREA, ³Dept. of Pediatrics, Dong Kang Medical Center, Ulsan, REPUBLIC OF KOREA, ⁴Dept. of Pediatrics, Presbyterian Hospital, Jeonju, REPUBLIC OF KOREA, ⁵Dept. of Pediatrics, Soon Chun Hyang Hospital, Cheonan, REPUBLIC OF KOREA.

20   A Study Using the In-Check Dial^® to Evaluate Peak Inspiratory Flow Rate from Thai Children Population Age 5-18 Years

T. Bunupuradah; Allergy and Immunology, Pediatrics department, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND.

21   Skin Test Reactivity in Children with Asthma and Rhinitis in New Orleans Prior to Hurricane Katrina

L. Kim ¹, J. M. El-Dahr²; ¹Allergy/Immunology, Tulane University Health Sciences Center, New Orleans, LA, ²Pediatric Allergy/Immunology/Rheumatology, Tulane University Health Sciences Center, New Orleans, LA.

Poster Session

2202

Saturday, March 04, 2006

9:45 am to 10:45 am

Pharmacotherapy of Asthma

22   Zileuton, 600 mg QID, Provides Early and Sustained Improvement in Pulmonary Function Compared to Placebo in Moderate and Severe Asthmatic Patients Versus Placebo

W. E. Berger ¹, J. J. Murray², G. N. Gross³, R. Menendez⁴, K. Walton-Bowen⁵; ¹Allergy and Asthma Associates of Southern California and Southern California Research, Mission Viejo, CA, ²Vanderbilt ASAP Research, Vanderbilt University Medical Center, Nashville, TN, ³Pharmaceutical Research and Consulting, Dallas, TX, ⁴Allergy and Asthma Center of El Paso, El Paso, TX, ⁵Clinical Operations, Biostatistical Analysis, and Reporting, Critical Therapeutics, Inc., Lexington, MA.

23   Monitoring of the Serum Levels of Endothelin and Eosinophil Cationic Protein in Children with Asthma Treated by Montelukast

F. Koprˇiva ^1,2; ¹Dept. of Pediatrics, Palacky University, Olomouc, CZECH REPUBLIC, ²Pediatrics, Palacky University, Olomouc, CZECH REPUBLIC.

24   Inhibitory Efficacy Of LTRA On Aspirin Induced Bronchospasm

J. Park; Division of Allergy and Respiratory Medicine, Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Bucheon, Gyeonggi Do, REPUBLIC OF KOREA.

25   The Improvement Combinational Effects of Oral Montelukast and Conventional Therapy on Airway Function for Treating Asthma Attacks

H. Sagara, K. Sugiyama, T. Okada, M. Ota, T. Fukuda; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo University School of Medicine, Tochigi, JAPAN.

26   A Case Study of Churg Strauss Syndrome with Montelukast and Inhaled Corticosteroids

S. A. Dyer¹, W. J. Geimeier ²; ¹Dept. of Medicine, Christiana Care, Newark, DE, ²Asthma & Allergy Care of Delaware, Newark, DE.

27   Pharmacological Profile of KP-496, a Novel Dual Antagonist for Cysteinyl Leukotriene Receptor (CysLT1R) and Thromboxane A₂ Receptor (TP)

M. Ishimura, M. Suda, S. Kataoka, T. Maeda, Y. Hiyama; Pharmacology Department, Kaken Pharmaceutical Co.,Ltd., Kyoto, JAPAN.

28   Effects of KP-496DPI, a Novel Dual Antagonist for Cysteinyl Leukotriene Receptor (CysLT1R) and Thromboxane A₂ Receptor (TP), on the Asthmatic Responses in Guinea Pigs

M. Suda ¹, K. Morizumi², M. Ishimura¹, T. Maeda¹, S. Kataoka¹, Y. Hiyama¹; ¹Pharmacology Department, Kaken Pharmaceutical Co., Ltd., Kyoto, JAPAN, ²Pharmacology Department, Panapharm Laboratories Co.,Ltd., Kumamoto, JAPAN.

29   Leukotriene Receptor Antagonist May Prevent the Progression of Preschool Children Asthma

M. Ebisawa, M. Ogata, T. Komata, T. Imai, M. Tomikawa, A. Shukuya, H. Tachimoto; Department of Allergy, Sagamihara National Hospital, Kanagawa, JAPAN.

30   Clinically Relevant Improvements in Asthma-Related Quality of Life in Patients Receiving Omalizumab as Add-On Therapy

W. Busse ¹, H. Fox², K. Surrey², R. Maykut³, C. Reisner³; ¹Department of Medicine, University of Wisconsin, Madison, WI, ²Novartis Horsham Research Centre, Horsham, UNITED KINGDOM, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ.

31   Omalizumab Induces Resolution of Fungal Sinusitis in a 15 Year Old Asthmatic Patient

R. Menendez; Allergy & Asthma Center of El Paso, El Paso, TX.

32   Add-On Omalizumab Improves Asthma Control across Multiple Measures of Response in Patients with Severe Persistent Allergic Asthma

W. Berger ¹, H. Fox², G. Ayre², M. Blogg², M. Massanari³, C. Reisner³; ¹Allergy and Asthma Associates of Southern California, Mission Viejo, CA, ²Novartis Horsham Research Centre, Horsham, UNITED KINGDOM, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ.

33   Safety of Anti-IgE Therapy with Omalizumab in Allergic Patients at Risk of Geohelminth Infection

P. J. Cooper ¹, F. Lima², E. C. Sarinho³, G. Ayre⁴, C. Martin⁴, H. Fox⁴, A. A. Cruz²; ¹Laboratorio de Investigaciones, Hospital Pedro Vicente Maldonado, Quito, ECUADOR, ²Centro de Enfermidades Respiratórias, Faculdade de Medicina da Bahia - UFBA, Salvador, BRAZIL, ³Departamento de Pediatria, Faculdade de Medicina da Universidade Federal de Pernambuco, Pernambuco, BRAZIL, ⁴Novartis Horsham Research Centre, Horsham, UNITED KINGDOM.

34   Omalizumab Downregulates the Expression of CD23 (FceRII) on Human Bronchial Smooth Muscle Cells (HBSMC) in Vitro

M. R. Streck, J. Tole, R. K. Gandhi, T. M. Loun, C. W. Stewart, D. B. Lew; Pediatrics, UT Memphis, Memphis, TN.

35   Omalizumab, an Anti-IgE Monoclonal Antibody, Demonstrates Long-Term Asthma Control, Safety and Tolerability in Patients with Severe Allergic Asthma

J. Hébert ¹, M. Rolli², J. Gao², C. Reisner²; ¹CRAAQ, Sainte-Foy, PQ, CANADA, ²Novartis Pharmaceuticals Corporation, East Hanover, NJ.

36   Anti-IgE Treatment Improves Lung Function In Patients With Mild Persistent Allergic Asthma

E. L. van Rensen¹, C. E. Evertse¹, S. A. Gauw¹, G. Ayre², P. J. Sterk¹, K. F. Rabe ¹; ¹Pulmonology, Leiden University Medical Center, Leiden, THE NETHERLANDS, ²Novartis, Horsham, UNITED KINGDOM.

37   Evaluating Response to Omalizumab Therapy in Clinical Practice

G. Ayre ¹, H. Fox¹, C. Reisner²; ¹Novartis Horsham Research Centre, Horsham, UNITED KINGDOM, ²Novartis Pharmaceuticals Corporation, East Hanover, NJ.

38   Omalizumab Reduced Need for Steroid Bursts and Improved Treatment Effectiveness in Asthmatics on Inhaled Salmeterol and Fluticasone Combination Therapy

M. Massanari ¹, F. Kianifard¹, R. Maykut¹, R. Zeldin¹, S. Hedgecock², C. Reisner¹, G. Geba¹; ¹Novartis Pharmaceuticals Corporation, East Hanover, NJ, ²Novartis Pharmaceuticals Corporation, Horsham, UNITED KINGDOM.

39   In Moderate-Severe Asthma, Omalizumab Reduced the Need for Rescue Systemic Steroid Bursts and Improved Ratings of Treatment Effectiveness: A Pooled Analysis

R. Maykut ¹, M. Massanari¹, R. Zeldin¹, F. Kianifard¹, Y. Deniz², C. Reisner¹, G. Geba¹; ¹Novartis, East Hanover, NJ, ²Genentech, So San Francisco, CA.

40   Anaphylaxis to Omalizumab after 14 Months of Successful Therapy

K. S. Price, L. Woodard, L. Pingle, M. Larson, K. Galloway, D. Graves; Allergy, Asthma and Dermatology Associates, PC., Portland, OR.

41   Neovastat Inhibits the VEGF production via HIF-2α Suppression in Murine Model of Asthma

S. Lee, S. Kwon, Y. Kim, S. Park; Internal Medicine, The Catholic University of Korea, Seoul, REPUBLIC OF KOREA.

42   Ciclesonide 160 μg Once Daily is as Effective as Budesonide 400 μg Once Daily in Pediatric Patients with Persistent Asthma

A. von Berg ¹, M. L. Garcia², S. Hellbardt³, T. D. Bethke³; ¹Marien-Hospital Wesel, Wesel, GERMANY, ²Hospital Severo Ochoa, Madrid, SPAIN, ³ALTANA Pharma AG, Konstanz, GERMANY.

43   Time of Achievement of Final Adult Height in Children Treated with Inhaled Budesonide

L. Agertoft, S. Pedersen; Dept. of Pediatrics, University of Southern Denmark, Kolding, DENMARK.

44   Ciclesonide, Administered Once Daily, has No Effect on Growth Velocity in Prepubertal Children with Mild, Persistent Asthma

D. Skoner ¹, J. Maspero², S. Kundu³, M. Lloyd³, D. Banerji³; ¹Allegheny General Hospital, Pittsburgh, PA, ²Sanatorio San José, Fundacion Cidea, Buenos Aires, ARGENTINA, ³Aventis Pharmaceuticals, a member of the sanofi-aventis Group, Bridgewater, NJ.

45   Subpotentcy of a Compounded Budesonide for Nebulization Product in a Patient with Poorly Controlled Asthma

G. J. WHELAN, J. D. SPAHN, E. E. BROWN, S. J. SZEFLER;

PEDIATRICS, NATIONAL JEWISH MEDICAL AND RESEARCH CENTER, DENVER, CO.

46   Enrollment Update of the Epidemiologic Study of Xolair: Evaluating the Long-Term Safety and Clinical Effectiveness in Patients with Moderate to Severe Asthma (EXCELS)

M. K. Miller ¹, J. H. Lee¹, D. Forer¹, A. Vaghar¹, E. Israel², M. Kraft³, F. Martinez⁴, D. Miller⁵, G. Shaprio⁶, R. Tarone⁷, S. Szefler⁸; ¹Genentech, Inc., South San Francisco, CA, ²Brigham and Women's Hospital, Boston, MA, ³Duke University Medical Center, Durham, NC, ⁴University of Arizona School of Medicine, Tucson, AZ, ⁵Harvard School of Public Health, Boston, MA, ⁶University of Washington, Seattle, WA, ⁷International Epidemiology Institute, Rockville, MD, ⁸National Jewish Medical and Research Center, Denver, CO.

Poster Session

2203

Saturday, March 04, 2006

9:45 am to 10:45 am

Innate Immunity

47   Pregnancy but not the Allergic Status Influences Innate Cytokine Responses

P. E. Amoudruz; Department of Immunology, Wenner-Gren Institute, Stockholm, SWEDEN.

48   Natural Killer (NK) Cell Subsets in Allergic Patients

F. Scordamaglia, G. Canonica, A. Scordamaglia; Allergy and Respiratory Diseases, University of Genoa, Genoa, ITALY.

49   Activation of Epithelial Cells and Lymphocytes by Staphylococcal Enterotoxin B Induces Profound Expression of Inflammatory Cytokines and Chemokines

D. A. Wagner, S. C. Shin, B. P. Tancowny, R. P. Schleimer, L. C. Grammer; Allergy and Immunology, Northwestern University, Chicago, IL.

50   Differential Regulation of Toll-like Receptor 3, 7, and 8 mRNA Expression in Human Airway Epithelial Cells

J. Y. Lee ¹, B. L. Zuraw², J. Eddleston²; ¹Division of Allergy, Asthma, and Immunology, Scripps Clinic, La Jolla, CA, ²Department of Medicine, University of California, San Diego and Veterans Medical Research Foundation, La Jolla, CA.

51   Role of Surfactant protein D in Murine and Human Allergic Airway Response

E. B. Brandt ¹, E. E. Muntel², G. K. Hershey¹, M. Stevenson³, J. A. Whitsett¹, M. E. Rothenberg¹; ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²University of Cincinnati, Cincinnati, OH, ³Akron Children's Hospital, Akron, OH.

52   The TLR7 Ligand Loxoribine Induces Pentraxin 3 Expression in Peripheral Blood Mononuclear Cells

J. I. Tirumalasetty ¹, S. C. Shin², A. C. Miranowski², Q. A. Truong-Tran², L. C. Grammer², P. A. Greenberger², R. P. Schleimer²; ¹Department of Allergy and Immunology, Northwestern University, Feinberg School of Medicine, Chicago, IL, ²Northwestern University, Chicago, IL.

53   Respiratory Syncytial Virus (rsv) Suppresses CD4 T Cell Proliferation through IFN-Alpha and IFN-Lambda

B. Chi, M. Alston, R. Rabin; CBER, US Food and drug administration, Bethesda, MD.

54   Expression of Acidic Mammalian Chitinase in Cord Blood Mononuclear Cells

M. Goldberg, O. Nadiv, N. Luknar-Gabor, Y. Katz; Institute of Allergy and Immunology, Assaf Harofeh Medical Center, Zerifin, ISRAEL.

55   Expression of Toll-Like Receptors on Neutrophils and Eosinophils Isolated from Individuals with and without Asthma

H. L. Peake, A. C. Prosser, P. J. Thompson; Asthma and Allergy Research Institute, Nedlands, Perth, Western Australia, AUSTRALIA.

56   Reduced Serum Levels of Innate Immune Molecules in Subjects with Frequent Asthma Exacerbations

E. T. Gardner ¹, C. Sheen¹, L. M. Stierman², B. Jovanovic², J. J. Shannon³, C. A. Saltoun¹, L. C. Grammer¹, R. P. Schleimer¹; ¹Allergy & Immunology, Northwestern University Feinberg School, Chicago, IL, ²Northwestern University, Chicago, IL, ³Medicine/Pulmonary & Critical Care, Cook County Hospital/ University of Illinois Medical School, Chicago, IL.

57   TLR3 Stimulation Induces Production of B Cell-Activating Factor of the TNF Family (BAFF) in Human Airway Epithelial Cells

A. Kato ¹, A. Q. Truong-Tran¹, A. Scott², K. Matsumoto³, R. P. Schleimer¹; ¹Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ³Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN.

58   Stat6 Activation by IL-4 Downregulates Toll-Like Receptor-4 Expression

P. O. Fiset, M. K. Tulic, S. M. Grover, P. S. A. Skrablin, S. Létuvé, B. D. Mazer, Q. Hamid; Medicine, Meakins Christie Laboratories, McGill University, Montreal, PQ, CANADA.

59   Requirement for the Classical Pathway of NF-kB Activation in NK Cell Cytotolytic Function

R. Pandey, R. P. Deering, M. Kienzle, P. P. Banerjee, J. S. Orange;

Division of Allergy and Immunology, University of Pennsylvania School of Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

60   Human Eosinophils Express Granzyme B and Perforin: Potential Role in Tumour Killing in Oral Squamous Cancer

F. Davoine ¹, A. Sim², T. Wierzbicki³, C. Leong³, L. Puttagunta², T. McGaw¹, D. Yu³, R. Moqbel¹; ¹Medicine, University of Alberta, Edmonton, AB, CANADA, ²Pathology, University of Alberta, Edmonton, AB, CANADA, ³Oral Medicine, University of Alberta, Edmonton, AB, CANADA.

61   TNFa Release Results in Increased Expression of the Innate Immune Regulatory Molecule Surfactant Protein D (SP-D) in a Model of Aspergillus fumigatus (Af) and Ozone-Induced Airway Inflammation

S. Kierstein ¹, Y. Cao¹, X. Yang¹, A. Das², A. Haczku¹; ¹Pulmonary, Allergy and Critical Care, University of Pennsylvania, Philadelphia, PA, ²Centocor, King of Prussia, PA.

62   House Dust Mite Allergen Der f Increase Bronchial Epithelial Cell Cytokine Expression

B. Sun; Dept of Medicine, Guangzhou Institute of Respiratory Diseases, Guangzhou, CHINA.

63   Il-21 Augments Function of Human Dendritic Cells

S. Desai, R. Pahwa, S. Pahwa; University of Miami, Miami, FL.

64   Enhancement of Host Defense Gene Expression by Glucocorticoids (GC) is Mediated by CCAAT-Enhancer Binding Protein (C/EBP)

N. Zhang, A. Q. Troung-Tran, B. Tancowny, R. P. Schleimer; Allergy and Immunology Division, Northwestern University Feinberg School of Medicine, Chicago, IL.

65   Impaired TLR Signaling in Mononuclear Cells from Patients with Food Allergy

L. C. Grammer; Feinberg School of Medicine, Northwestern University, Chicago, IL.

66   Expression of Plasminogen Activator Inhibitor 2 (PAI-2) in Response to Rhinovirus Infection

H. Dagher ¹, K. Hanson¹, R. Brockman-Schneider¹, W. Lee², A. Mosser³, J. Gern¹; ¹Department of Pediatrics, University of Wisconsin, Madison, WI, ²Department of Pediatric and Medicine, University of Wisconsin, Madison, WI, ³Department of Medicine, University of Wisconsin, Madison, WI.

67   Human Mast Cell Cytotoxicity against Human Lymphoma and Myeloid Leukemia Cells

O. Ozdemir; Pediatric Allergy/Immunology, Louisiana State University Health Sciences Ctr., New Orleans, LA.

Poster Session

2204

Saturday, March 04, 2006

9:45 am to 10:45 am

Autoimmunity

68   Observation of Sjögren's Syndrome in IL-14a Transgenic Mice

C. XU; Allergy, immunology and rheumatology, SUNY at Buffalo School of Medicine and Biomedical sciences, Buffalo, NY.

69   Oral Administration Decreases Autoimmune Hearing Loss Lesion in the Mice

Q. Cai, T. Yoo; Allergy and immunology, Medicine, Memphis, TN.

70   Somatic Mosaicism of CIAS1 in a Patient with Chronic Infantile Neurologic, Cutaneous, Articular Syndrome

M. Saito ¹, R. Nishikomori¹, A. Fujisawa², N. Kambe², M. N. Hizume¹, I. Okafuji¹, T. Yoshioka¹, M. Yoshimoto¹, K. Omori³, T. Kusunoki¹, T. Heike¹, Y. Miyachi², T. Nakahata¹; ¹Pediatrics, Kyoto University Graduate School of Medicine, Kyoto, JAPAN, ²Dermatology, Kyoto University Graduate School of Medicine, Kyoto, JAPAN, ³Central Clinical Laboratory, Kyoto University Hospital, Kyoto, JAPAN.

71   Overproduction of IL-4 Leads to Lymphocyte Hyper-Activation, Elevated IgE, and Autoimmunity in the Flaky Skin (fsn) Mouse

B. L. Hill; Applied Medical Sciences, University of Southern Maine, Portland, ME.

72   IL-14 RNA Levels in the Peripheral Blood Leukocytes of Patients with SLE

S. Kiratiseavee, L. Shen, A. N. Baer, J. L. Ambrus, Jr.; Allergy/Immunology/Rheumatology, SUNY at Buffalo, Buffalo, NY.

73   Resolution of PANDAS Like Symptoms by IVIG in a Patient with Specific Antibody Deficiency against Polysaccharide Antigens

A. L. B. Hersh, L. Geng, A. Cushing-Ruby, H. Jyonouchi; Allergy and Immunology, UMDNJ, Newark, NJ.

74   ABR and DPOAE in Tubulin Based Induced Autoimmune Hearing Loss

M. Habiby Kermany, B. Zhou, M. Yoon, T. Yoo; Allergy/ Immunology, University of Tennessee, Memphis, TN.

75   Functional Regulation of Normal and SLE Plasma Cells by DCC (Deleted in Colon Cancer) and its Ligand Netrin-1

P. L. Lugar ¹, R. Slota¹, R. T. Fischer¹, D. Withers¹, P. Pisitkun¹, P. E. Lipsky², A. C. Grammer¹; ¹Niams, dhhs, NIH, Bethesda, MD, ²Niams, dhhs, Autoimmunity Branch, NIH, Bethesda, MD.

76   Infliximab Related Lupus and Associated Valvulitis

T. Chadha, J. E. Hernandez; Baylor College of Medicine, Houston, TX.

77   Characterization of Immune Response In b-tubulin Induced Murine Autoimmune Hearing Loss

C. CAI, B. ZHOU, J. GLICKSTEIN, T. J. YOO; UNIVERSITY OF TENNEESSEE, MEMPHIS, TN.

78   Activin A Deficiency: Association with Autoimmune Lung Disease

M. J. Thomassen ¹, T. L. Bonfield², B. P. Barna², N. John², M. S. Kavuru¹; ¹Pulmonary and Critical Care, East Carolina University, Greenville, NC, ²Dept of Pulmonary, Allergy & Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, OH.

79   [Withdrawn]

80   The Spontaneous and Induced Production of Fas-ligand by Eosinophils from Subjects with Aspirin Hypersensitivity, Allergic Rhinitis and Healthy Volunteers

I. Kuprys-Lipinska, M. Kupczyk, M. Bochenska-Marciniak, P. Gorski, P. Kuna; Allergy and Pneumonology, Barlicki University Hospital, Lodz, POLAND.

81   The il14 Gene is a Candidate Gene for sle2

L. Shen, C. Zhang, T. Wang, C. Xu, S. Brooks, J. L. Ambrsu, Jr.;

Medicine, University at Buffalo, SUNY, Buffalo, NY.

82   Diagnostic and Prognostic Value of Soluble P-Selectin and D-Dimer in Juvenile Rheumatoid Arthritis

Y. M. El-Gamal ¹, N. M. Heshmat¹, E. M. Hossny¹, H. M. Afifi², A. M. El-Shibiny³, Z. E. Hasan¹; ¹Pediatrics, Ain Shams University, Cairo, EGYPT, ²Clinical pathology, Ain Shams University, Cairo, EGYPT, ³Radiology, Ain Shams University, Cairo, EGYPT.

83   T-Cell Regulated Neutrophilic Inflammation in Auto-Inflammatory Diseases

M. Keller ¹, Z. Spanou¹, P. Schaerli², M. Britschgi¹, N. Yawalkar³, M. Seitz¹, P. M. Villiger¹, W. J. Pichler¹; ¹Clinic of Rheumatology and Clinical Immunology/Allergology, University Hospital, Bern, SWITZERLAND, ²Department of Pathology, The CBR Institute for Biomedical Research, Harvard Medical School, Boston MA 02115, MA, ³Department of Dermatology, University Hospital, Bern, SWITZERLAND.

84   Serum Levels of Vascular Endothelial Growth Factor in Children and Adolescents with Systemic Lupus Erythematosus

N. M. Heshmat ¹, T. H. El-Kerdany²; ¹Pediatrics, Ain Shams University, Cairo, EGYPT, ²Clinical Pathology, Ain Shams University, Cairo, EGYPT.

85   Raising the Curtain on PFAPA Syndrome - New Aspects Revealed

I. Dalal, D. Tesher, E. Somekh; Pediatric Infectious/Allergy/ Immunology Unit, Pediatric Department, E. Wolfson Medical Center, Holon, ISRAEL.

86   Angioedema in a Girl with Primary C4B Deficiency

L. Yao ¹, Y. L. Wu², Y. Yu², R. Sorensen¹; ¹Allergy & Immunology, LSUHSC-NO, New Orleans, LA, ²Pediatrics, Columbus Children Research Institute, Columbus, OH.

Poster Session

2205

Saturday, March 04, 2006

9:45 am to 10:45 am

Indoor Air Quality In and Out of the Workplace

87   Effect of Endotoxin on Metal Working Fluid Induced Hypersensitivity Pneumonitis in Mice

M. C. Zacharisen ¹, C. Barrios², V. P. Kurup², J. N. Fink¹; ¹Pediatrics, Medical College Of Wisconsin, Milwaukee, WI, ²Pediatrics, VA Medical Center, Milwaukee, WI.

88   The Implications of Hypersensitivity Pneumonitis (HP) Precipitin Assays in the Diagnosis of Immune Lung Diseases

M. R. Murali; Medicine, Division of Rheumatology, Allergy and Clinical Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

89   VEGF Driven Airway Inflammation was Augmented in Subjects with NK2R 7853 CC Genotype among the Toluene Diisocyanate Exposed Workers

Y. Ye ¹, J. Choi², S. Kim³, S. Kim¹, D. Nahm¹, H. Park¹; ¹Dept. of Allergy & Rheumatology, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA, ²Dept. of Pulmonology & Allergy, Bundang Jesaeng General Hospital, Seongnam, REPUBLIC OF KOREA, ³Dept. of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, REPUBLIC OF KOREA.

90   Relationship between Inflammation and Phase II Enzymes in Response to Diesel Exhaust Particles

E. M. Lin, D. Diaz-Sanchez; Clinical Immunology and Allergy, University of California at Los Angeles, Los Angeles, CA.

91   Low Exposure To Inhaled Formaldehyde: Effect On Allergen Bronchial Response In Asthmatics Sensitized To Mite

A. CASSET ^1,2, C. MARCHAND³, A. PUROHIT¹, S. LE CALVE³, C. DONNAY¹, P. MEYER⁴, G. PAULI^1,2, F. DE BLAY^1,2; ¹Hôpital Lyautey, Hôpitaux Universitaires de Strasbourg, Strasbourg, FRANCE, ²Ea 3771, Université Louis Pasteur, Strasbourg, FRANCE, ³Centre de Géochimie de la Surface, CNRS (UMR 7517), Strasbourg, FRANCE, ⁴Service de Biostatistiques et Informatique Médicale, Faculté de Médecine, Strasbourg, FRANCE.

92   Exercise in Cold Air Increases Cough Sensitivity to Capsaicin in Patients with Chronic Cough due to Sensory Hyperreactivity

E. Millqvist, E. Ternesten-Hasséus, E. Johansson, O. Löwhagen;

Department of Respiratory Medicine and Allergy, The Sahlgrenska Academy at Göteborg University, Göteborg, SWEDEN.

93   Low Dose Inhaled Endotoxin Induces Elevated Neutrophils in the Airways, A Response Not Observed in Normal Volunteers

N. Alexis ^1,2, J. C. Lay^1,2, D. B. Peden^1,2; ¹Pediatrics, Center Environmental Med Asthma & Lung Biology, Chapel Hill, NC, ²UNC Chapel Hill, Chapel Hill, NC.

94   The Effects of Three Polycyclic-Aromatic Hydrocarbons on Interleukin-4 and Interferon Gamma Production among Atopic Individuals

J. S. Collins, X. Mao, C. Wang, R. L. Miller; Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University, New York, NY.

95   Expression of Latex Allergens on Inner and Outer Surfaces of Latex Surgical Gloves

P. M. Tavares ¹, C. M. A. Peixinho¹, M. R. T. Tomás², L. M. P. Taborda-Barata¹, C. A. T. Tomaz¹; ¹Department of Medical Sciences, University of Beira Interior, Health Sciences Research Centre, Covilha, PORTUGAL, ²Department of Internal Medicine, Viseu District Hospital, Viseu, PORTUGAL.

96   Occupational Allergy Caused by Inhalation of Pancreatic Extracts in Medical Personnel and Identification of The Major Allergens

S. H. Kim ¹, H. S. Park², Y. M. Ye², K. C. Shin¹, S. J. Yong¹; ¹Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, REPUBLIC OF KOREA, ²Allergy and Rheumatology, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA.

97   Receiver Operating Characteristics (ROC) Analysis of the IMMULITE^®-2000 3gAllergy^™ for the Diagnosis of Latex Allergy

R. E. Biagini ¹, B. A. MacKenzie¹, D. L. Sammons¹, S. A. Robertson¹, E. F. Krieg, Jr.¹, R. G. Hamilton²; ¹CDC/NIOSH, Cincinnati, OH, ²Johns Hopkins University School of Medicine, Baltimore, MD.

98   Occupational Asthma Caused by Styrene in an Autobody Shop Worker

M. Fernandez-Nieto ¹, S. Quirce¹, J. Fraj², V. del Pozo³, B. Sastre³, C. Seoane³, C. Lahoz³, J. Sastre¹; ¹Allergy, Fundacion Jimenez Diaz, Madrid, SPAIN, ²Allergy, Hospital Clinico, Zaragoza, SPAIN, ³Immunology, Fundacion Jimenez Diaz, Madrid, SPAIN.

99   Clarinettist´s Cheilitis by Allergy to Cane Reed

J. Ruiz-Hornillos ¹, E. Alonso¹, C. Perez¹, G. Davila¹, M. Lombardero², L. Zapatero¹, I. Martinez-Molero¹; ¹Hospital General Universitario Gregorio Marañon, Madrid, SPAIN, ²ALK-ABELLO, Madrid, SPAIN.

100   Occupationally Induced Allergy to the Soybean Cyst Nematode, Heterodera Glycines

J. K. Lemmon, P. S. Hutcheson, H. C. Gray, R. G. Slavin; Division of Allergy and Immunology, Department of Internal Medicine, Saint Louis University School of Medicine, St Louis, MO.

101   Cigarette Smoke-Induced Gene Expression Analysis in Normal Human Bronchial Epithelial Cells

A. R. Jones ^1,2, J. W. Beckstead², R. F. Lockey^1,3, S. S. Mohapatra^1,3;

¹University of South Florida, Tampa, FL, ²College of Nursing, University of South Florida, Tampa, FL, ³James A. Haley Veterans’ Administration Hospital, Tampa, FL.

102   High Indoor Air Pollution in Public Housing Homes

E. Horowitz ¹, D. A. Collins¹, J. Poyser¹, T. Green¹, T. Richards¹, R. Morgan¹, D. A. Williams², P. N. Breysse², A. Togias¹; ¹Johns Hopkins Asthma and Allergy Center, Baltimore, MD, ²Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.

103   Indoor Fungal Spore Levels Before and After Simple Home Repair and Asthma Education

P. Dowling, F. Hu, L. Johnson, K. Kennedy, C. S. Barnes; Allergy/ Asthma/Immunology, Children's Mercy Hospital, Kansas City, MO.

104   Tobacco and Other Drug Use Among High School Students with Asthma

S. Merkle ¹, S. Everett Jones¹, L. Wheeler¹, D. M. Mannino², L. Crossett¹;

¹Division of Adolescent and School Health, Centers for Disease Control and Prevention, Atlanta, GA, ²Division of Environmental Hazards and Health Effects, Centers for Disease Control and Prevention, Atlanta, GA.

105   Indoor Air Quality (IAQ) and Water Damages in Finnish Hospitals

K. E. Reijula;

Finnish Institute of Occupational Health, Helsinki, FINLAND.

106   Fungal Ergosterol Levels in Typical Homes

K. Wagoner, L. D. Johnson, F. Pacheco, J. Portnoy, C. S. Barnes;

Allergy/Asthma/Immunology, Children's Mercy Hospital, Kansas City, MO.

Poster Session

2206

Saturday, March 04, 2006

9:45 am to 10:45 am

Airborne Allergens, Environmental Exposure Assessment and Abatement

107   Cockroach Allergen Reduction by Extermination Alone in Low-Income, Urban Homes-A Randomized Control Trial

M. Sever ¹, S. J. Arbes, Jr.¹, J. C. Gore², R. G. Santangelo², B. Vaughn³, H. Mitchell³, C. Schal², D. C. Zeldin¹; ¹Division of Intramural Research, NIEHS/NIH, Research Triangle Park, NC, ²Department of Entomology, North Carolina State University, Raleigh, NC, ³Rho, Inc., Chapel Hill, NC.

108   Mite-proof covers: Mite Penetration of Different Types of Materials Claimed to be Mite-proof by the Siriraj Chamber Method

V. Mahakittikun ¹, C. Sirikasemlert², N. Rungsimuntakul², P. Deemark³, J. J. Boitano⁴, E. Tovey⁵, T. Matsumoto⁶, C. Andre⁷; ¹Parasitology, Mahidol University, Bangkok, THAILAND, ²Thailand Textile Institute, Bangkok, THAILAND, ³Thailand Textile Institute, Bangkok, THAILAND, ⁴Mahidol University, Stratford, CT, ⁵Woolcock Institute of Medical Research, Sydney, AUSTRALIA, ⁶Child Development, Kumamoto University, JAPAN, ⁷Scientific and Medical Department, FRANCE.

109   Adjuvant Activity of Ambient Particulate Matter on Allergic Immune Response to Alternaria Alternata

H. M. Vijay, V. Kumar, M. Abebe, S. Sevinc, R. Vincent; Environmental health, Environmental Health Directorate, Ottawa, ON, CANADA.

110   The Type of Clinically Relevant Allergen Influences the Course of Respiratory Allergy: 3-Year Prospective Study

M. Marogna ¹, A. Massolo², G. Passalacqua³; ¹Pneumology Unit, Macchi Hospital, Varese, ITALY, ²Allergy and Respiratory Diseases, University of Siena, Siena, ITALY, ³Allergy & Respiratory Diseases Dept of Internal Medicine, Genoa University, Genova, ITALY.

111   High Throughput Fluorescent Multiplex Array for Indoor Allergen Exposure Assessment

C. D. Earle ¹, A. Tsay¹, B. Saric¹, R. Godbout², K. G. Oliver², M. D. Chapman¹; ¹Indoor Biotechnologies Inc., Charlottesville, VA, ²Radix Biosolutions Inc., Austin, TX.

112   Ultraviolet C Exposure is Fatal to American House Dust Mite Eggs

G. Needham ¹, C. Begg², S. Buchanan³; ¹Entomology, The Ohio State University, Columbus, OH, ²Materials Science Engineering, The Ohio State University, Columbus, OH, ³Molecular, Cellular and Developmental Biology, The Ohio State University, Columbus, OH.

113   Effectiveness of Vital Oxide for Controlling Fungal Contamination on Building Materials

E. Levetin; Biological Science, University of Tulsa, Tulsa, OK.

114   Harmonia Axyridis (Asian Lady Bug) an Evolving Indoor Allergen

T. NAKAZAWA, L. Naccara, L. E. Goddard, T. A. Platts-Mills; Asthma & Allergy Center, University of Virginia, Charlottesville, VA.

115   Diurnal Variation of Airborne Ragweed Pollen in A Metropolitan Area - An 8 Year Perspective

B. Jones, C. Barnes, J. Portnoy, F. Hu; Allergy/Immunology, Children's Mercy Hospital, Kansas City, MO.

116   Harmonia axyridis Ladybug Hypersensitivity in Clinical Allergy Practice

D. W. Goetz; Exemplar Allergy and Asthma, Morgantown, WV.

117   Initial Characterization of Monoclonal Antibodies Against the Fungal Hemolysin Stachylysin from Stachybotrys chartarum

D. Schmechel ¹, B. J. Green¹, F. M. Blachere¹, S. J. Vesper², D. Beezhold¹; ¹Health Effects Laboratory Division, CDC/Natl. Inst. Occup. Safety & Health, Morgantown, WV, ²National Exposure Research Laboratory, U.S. Environmental Protection Agency, Cincinnati, OH.

118   Ladybug Hypersensitivity Among Residents of Homes Infested with Ladybugs in Kentucky

K. Sharma ¹, S. Muldoon¹, M. F. Potter², H. L. Pence¹; ¹University of Louisville School of Medicine, Louisville, KY, ²University of Kentucky, Lexington, KY.

119   IgE Antibodies to Mouse Urinary Allergens in Sera from Urban Asthmatics: How do we tell if it is an Important Allergen?

L. M. Naccara ¹, M. Carter², E. Peters³, E. Erwin¹, T. A. E. Platts-Mills¹; ¹Division of Asthma, Allergy, and Immunology, University of Virginia, Charlottesville, VA, ²Division of Asthma, Allergy, and Immunology, National Institute of Health, Bethesda, MD, ³Allergy & Immunology, Austin, TX.

120   Bed Encasings Reduce Reservoir Allergens but not Aeroallergens

J. Y. Lau, J. K. Sercombe, J. S. Rimmer, E. R. Tovey; Woolcock Institute of Medical Research, Sydney, AUSTRALIA.

121   Localization of Species-Specific Antibody Binding Sites to Stachybotrys Chartarum Using the Halogen Immunoassay

B. J. Green, D. Schmechel, L. Millecchia, F. Blachere, D. Beezhold; National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV.

122   Application of Building Science Principles to Reduction of Indoor Air Pathogens

W. P. Dean, Jr.; The Phoenix Group, Naples, FL.

123   A Survey Analysis of Allergist's Attitudes Toward Environmental Control

D. M. Brandt ¹, L. Levin², J. A. Bernstein¹; ¹Internal Medicine, University of Cincinnati, Cincinnati, OH, ²Environmental Health, University of Cincinnati, Cincinnati, OH.

124   Environmental Factors Found in Homes of Asthmatics

M. C. Amado, F. Pacheco, K. Kennedy, L. Johnson, C. S. Barnes; Allergy/Asthma/Immunology, Children's Mercy Hospital, Kansas City, MO.

125   Predictors of Clinical Food Allergy in Patients with Pollen Rhinitis

M. Corominas, R. Lleonart; Allergology, Hospital Universitari de Bellvitge, L'Hospitalet Llobregat (Barcelona), SPAIN.

126   Prevalence and Characteristics of Sensitization to Rabbit in Italy. A Multicentric Survey

G. Passalacqua ¹, G. Liccardi²; ¹Allergy & Respiratory Diseases Dept of Internal Medicine, Genoa University, Genova, ITALY, ²Dept of Chest Diseases, Pneumology and Allergology, A. Cardarelli Hospital, Naples, ITALY.

Poster Session

2207

Saturday, March 04, 2006

9:45 am to 10:45 am

The “Nut” Allergies

127   Cross-Reactivity Among Almond, Peanut and Other Tree Nuts in Almond Allergic Patients

A. Kewalramani ¹, S. J. Maleki², H. Cheng², S. Teuber³; ¹Division of Clinical Immunology, Allergy & Rheumatology, Tulane University Health Sciences Center, New Orleans, LA, ²Southern Regional Research Center, United States Department of Agriculture, New Orleans, LA, ³Division of Rheumatology, Allergy & Clinical Immunology, Univeristy of California, Davis, School of Medicine, Davis, CA.

128   Assessing the Impact of Government Advice to Pregnant Mothers to Avoid Peanut on the Prevalence of Peanut Allergy in UK Children at School Entry

J. O. Hourihane ¹, R. Aiken², R. A. Briggs³, S. R. Roberts²; ¹Paediatrics and Child Health, University College Cork, Cork, IRELAND, ²Paediatrics, South Manchester University Hospitals Trust, Manchester, UNITED KINGDOM, ³Infection, Inflammation and Repair, University of Southampton, Southampton, UNITED KINGDOM.

129   Re-establishment of Oral Tolerance to Peanut in Allergic Mice by the Chinese Herbal Medicine Formula FAHF-2 is Associated with Up-regulation of Mesenteric IFN-g producing CD8⁺ Cells

J. Ko, C. Qu, K. Srivastava, T. Zhang, H. A. Sampson, X. Li; Mount Sinai Medical Center, New York, NY.

130   Different Prevalence of Peanut Allergy in Children in Israel and UK is Not Due to Differences in Atopy

G. Du Toit ¹, Y. Katz², P. Sasieni³, D. Nitzan Kaluski⁴, I. Irit Livne⁵, G. Lack¹; ¹Department of Paediatric Allergy, St Marys Hospital, London, UNITED KINGDOM, ²Sackler School of Medicine, Allergy & Immunology Institute, Assaf-Harofeh, Tel-Aviv University, ISRAEL, ³Cancer Research UK Centre for Epidemiology, Mathematics & Statistics, Queen Mary, University of London, London, UNITED KINGDOM, ⁴Food & Nutrition Administration, Ministry of Health, Israel, Tel Aviv, ISRAEL, ⁵School Health and Health Education, Jerusalem, ISRAEL.

131   Anti-Peanut Ige in 130 Patients According to the Sensitization to Grass Pollens

L. GUILLOUX ¹, D. Moneret-Vautrin², M. Morisset², F. Codreanu², L. Parisot², G. Kanny²; ¹Marcel Merieux Laboratory, Lyon, FRANCE, ²Central Hospital, Nancy, FRANCE.

132   Peanut Specific IgG4 and its Association with Peanut Allergy

S. Hingley, G. Du Toit, G. Roberts, V. Turcanu, G. Lack, H. Fisher, P. Lau; Department of Paediatric Allergy, Imperial College at St Marys Hospital, London, UNITED KINGDOM.

133   Pharmacologic and Immunologic Effects of Individual Herbs of Food Allergy Herbal Formula 2 in a Murine Model of Peanut Allergy

J. D. Kattan, K. D. Srivastava, H. A. Sampson, X. Li; Pediatrics, Mount Sinai School of Medicine, New York City, NY.

134   Peanut Allergen Exposure through Kissing (Saliva): Assessment and Intervention

J. M. Maloney ¹, M. Chapman², S. H. Sicherer¹; ¹ALLERGY/ iMMUNOLOGY, Mount Sinai Medical Center, NY, NY, ²ALLERGY/iMMUNOLOGY, INDOOR Biotechnologies Inc, Charlottesville, VA.

135   Determination of Allergenic Cross-Reactivity between 11S-Globulins (Seed Storage Proteins) in Peanut, Tree-Nut and Sesame Allergic Patients Using Peptide Microarray Immunoassay

D. A. Lencer ¹, L. Rosenfeld², L. Bardina¹, W. G. Shreffler¹, H. A. Sampson¹, K. Beyer²; ¹Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY, ²Pediatric Allergy and Immumology, Charite Berlin, Berlin, GERMANY.

136   Peanut Allergy Diagnosis : Comparison of Three Commercial Specific IgE Assays

H. Malandain ¹, J. L. Fauquert², A. Tridon³, H. Susini de Luca⁴, S. Ughetto⁵, Y. Cano¹; ¹Clinical Biochemistry Laboratory, Chubert Hospital, Vannes, FRANCE, ²Department of Pediatrics, University Hospital, Clermont-Ferrand, FRANCE, ³Department of Immunology, University Hospital, Clermont-Ferrand, FRANCE, ⁴L.A.B.M., Fouesnant, FRANCE, ⁵Department of Public Health, Medical University, Clermont-Ferrand, FRANCE.

137   Clinical Characteristics of Patients with Peanut Allergy

T. D. Green ¹, G. S. Labelle¹, P. H. Steele¹, L. A. Lee¹, V. S. Mankad¹, L. W. Williams¹, K. J. Anstrom², A. W. Burks¹; ¹Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC, ²Duke Clinical Research Institute, Duke University Medical Center, Durham, NC.

138   Early Exposures to Peanut and Sensitization at a Children's Hospital Clinic

A. P. Stallings, A. D. Hogan; Pediatrics, Children's Hospital of the King's Daughters, Eastern Virginia Medical School, Norfolk, VA.

139   Development of an ELISA for Digestion-Resistant Ara h 2 Peptide: Monitoring the Peptide in Body Fluids of Healthy Volunteers Who Consumed Peanut

J. L. Baumert ¹, K. A. Peeters², A. C. Knulst², S. J. Koppelman², S. J. Maleki³, E. Knol², S. L. Hefle¹; ¹Food Allergy Research & Resource Program, University of Nebraska, Lincoln, NE, ²Department of Dermatology/Allergology, University Medical Center, Utrecht, THE NETHERLANDS, ³Agricultural Research Service, Southern Regional Research Center, U.S. Department of Agriculture, New Orleans, LA.

140   Risk of Peanut Allergy Associated with High Household Exposure to Peanut in Infancy

A. T. Fox ¹, G. L. du Toit¹, H. Syed², P. Sasieni², G. Lack¹; ¹Paediatric Allergy, Imperial College, London, London, UNITED KINGDOM, ²Cancer Research UK Centre of Epidemiology, Mathematics and Statistics, Wolfson Institute of Preventive Medicine, London, UNITED KINGDOM.

141   Lunch Guidelines Are Effective in Reducing Peanut Substances in Primary School Classrooms in Montreal, Canada

D. K. Banerjee ^1,2, R. S. Kagan¹, E. Turnbull³, L. Joseph⁴, Y. St. Pierre³, C. Dufresne⁵, K. Gray-Donald⁶, A. E. Clarke^1,3; ¹Division of Clinical Immunology/Allergy, McGill University Health Centre, Montreal, PQ, CANADA, ²Rockefeller University, New York City, NY, ³Clinical Epidemiology, McGill University Health Centre, Montreal, PQ, CANADA, ⁴Epidemiology and Biostatistics, McGill University, Montreal, PQ, CANADA, ⁵Association Québécoise des Allergies Alimentaires, Montreal, PQ, CANADA, ⁶School of Dietetics and Human Nutrition, McGill University, Ste. Anne de Bellevue, PQ, CANADA.

142   Food Allergy Management from the Perspective of Restaurant/Food Establishment Personnel

R. N. Ahuja¹, J. Hsi¹, S. H. Sicherer ²; ¹Valley Stream South High School, New York, NY, ²Pediatrics, Mt Sinai School Of Medicine, New York, NY.

143   Frequency and Significance of Immediate Contact Reactions to Peanut in Food-Sensitive Children

B. Wainstein ¹, J. B. Ziegler¹, A. Yee¹, M. Ziegler¹, D. Jelley¹, S. Kashef²; ¹Immunology, Sydney Children's Hospital, Sydney, AUSTRALIA, ²Shiraz University of Medical Sciences, Shiraz, IRAN (ISLAMIC REPUBLIC OF).

144   Avidity of IgG and IgE in Peanut Allergic Individuals

S. A. Lewis ^1,2, F. El-Khouly¹, L. Pons³, W. Burks³, J. O. Hourihane¹; ¹IIR, University of Southampton, Southampton, UNITED KINGDOM, ²Safety and Environmental Assurance Centre, Unilever, Sharnbrook, UNITED KINGDOM, ³Division of Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC.

145   Food Allergy in Lebanon : Is Sesame the “Middle Eastern” Peanut

C. Irani ^1,2, M. Germanos³, H. Kazma⁴, V. Merhej³; ¹Internal Medicine-Allergy/Immunology Section, Hotel Dieu de France University Medical Center, Beirut, LEBANON, ²Internal Medicine, Hammoud Hospital University Medical Center, Saida, LEBANON, ³Laboratory of Hematology/Immunology, Hotel Dieu de France University Medical Center, Beirut, LEBANON, ⁴Hematology/Immunology, Hammoud Hospital University Medical Center, Saida, LEBANON.

146   First Allergic Reaction to Nuts or Peanuts From Candy Bars Labelled “May Contain Nuts/Peanuts” in Older Children

M. Primeau; Pediatirc, Sainte-Justine Hospital, University of Montreal, Montreal, PQ, CANADA.

147   Cosensitization of Peanut and Soybean in Children Under 3 Years with Atopic Dermatitis

Y. Shin ¹, K. Chun², N. Koo², S. Oh², M. Sohn³, K. Kim³, S. Lee²; ¹Department of Pediatrics, Pochon CHA University College of Medicine, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA, ³Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA.

148   Risk of Peanut Allergy in Tree Nut Allergic Patient

J. M. DeMasi ¹, J. C. DeMasi²; ¹Pediatrics, Albany Medical College, Albany, NY, ²Biology, University of North Carolina, Chapel Hill, NC.

149   Changing Ethnicity in Peanut Allergy

A. T. Fox, H. Kaymakcalan, G. Lack; Paediatric Allergy, Imperial College at St Mary's Hospital, London, London, UNITED KINGDOM.

150   Relevance of Peanut-Specific Ige Levels to the Development of Food Hypersensitivity in Atopic Young Children

S. Shin, J. Oh, H. Lee; Department of Pediatrics, Hanyang University School of Medicine, Seoul, REPUBLIC OF KOREA.

151   Effect of Phytic Acid on IgE Binding to Peanut Allergens

S. Chung, E. T. Champagne; USDA-ARS, SRRC, New Orleans, LA.

152   Cortex Phellodendron (huang Bai) but not its Major Ingredient Berberine Blocks Anaphylactic Reactions in a Murine Model of Peanut Allergy

T. Zhang, Z. Zou, H. A. Sampson, X. Li; Pediatrics, Allergy & Immunology, Mount Sinai School of Medicine, New York, NY.

153   Maillard Reaction Alters The IgE and Antibody Binding Properties of Ara h 6

J. Sotolongo, H. Cheng, S. J. Maleki; Food Allergy Unit, USDA-Agricultural Research Service, New Orleans, LA.

154   In Vitro Cross-Reactivity of Peanut Allergens with Other Legumes

R. S. Bonds ¹, S. J. Maleki², J. McBride², H. Cheng²; ¹Ochsner Clinic Foundation, New Orleans, LA, ²USDA-SRRC, New Orleans, LA.

Poster Session

2208

Saturday, March 04, 2006

9:45 am to 10:45 am

Beyond the “Nut” Allergies

155   Determination of Epitope Diversity in Cow's Milk Hypersensitivity Using Microarray Immunoassay

J. Wang, L. Bardina, D. Lencer, W. G. Shreffler, H. A. Sampson;

Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY.

156   Evaluation of Cellular Immune Reactivity to Candida Antigen in Young Children with Non-Allergic Food Hypersensitivity (NFH) to Cow's Milk Protein (CMP)

N. S. Ogden, L. Geng, H. Jyonouchi; Allergy & Immunology, UMDNJ-Newark, New York, NY.

157   Allergy to an Amino-Acid Formula in Infants: Residual Soy Allergens in Soybean Oil are Incriminated

M. Morisset ¹, T. Lee², F. Codreanu¹, V. Cordebar¹, S. Fremont³, L. Guenard¹, G. Kanny¹, D. Moneret-Vautrin¹; ¹Department of Internal Medicine, Clinical Immunology and Allergology, University Hospital, Nancy, FRANCE, ²Molelucar and Therapeutic Medicine, Genclis. Vandoeuvre, FRANCE, ³Biochemistry Laboratory, Hopital Central, Nancy University Hospital, Nancy University Hospital, FRANCE.

158   The Natural History of Cow's Milk Allergy (CMA)

J. M. Skripak, E. C. Matsui, R. A. Wood; Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, MD.

159   Novel in Vitro Method for Diagnosis of Food Allergy in Children: Utilization Of CD203c Expression in Basophils

M. Nagao ^1,2, R. Tokuda^1,3, Y. Noma^1,4, S. Nakayama⁵, T. Fujisawa^1,2; ¹Institute for Clinical Research, Mie National Hospital, Tsu, JAPAN, ²Pediatrics, Mie National Hospital, Tsu, JAPAN, ³Tokuda Family Clinic, Ise, JAPAN, ⁴Pediatrics, Mie Prefectural General Medical Center, Yokkaichi, JAPAN, ⁵Biomedical Research, Beckman Coulter KK, Tokyo, JAPAN.

160   Validity of Diagnostic Tests in Egg Allergy

M. DIEGUEZ ¹, A. MURIEL², B. DE LA HOZ¹, I. CERECEDO¹, M. ANTON¹, E. CAMACHO¹, M. SANCHEZ CANO¹; ¹ALLERGY, HOSPITAL RAMON Y CAJAL, MADRID, SPAIN, ²Unidad de bioestadistica, HOSPITAL RAMON Y CAJAL, MADRID, SPAIN.

161   What Specific IgE Levels to Milk Protein Fractions May Contribute to Cow's Milk (CM) Allergy Diagnosis?

A. P. M. Castro, A. K. F. Gushken, A. C. Pastorino, E. Ciccone, A. C. Brandao, C. M. A. Jacob; Department of Pediatrics, University of Sao Paulo, Sao Paulo, BRAZIL.

162   Cow's Milk Allergy: A Pilot Trial of Sublingual Immunotherapy

d. de boissieu, C. Dupont; St Vincent de Paul Hospital, Paris, FRANCE.

163   Seafood Allergic Reactions in Restaurants

T. J. Furlong ¹, J. M. Maloney², S. H. Sicherer²; ¹Food Allergy Network, Fairfax, VA, ²Allergy/Immunology, Mount Sinai Medical Center, NY, NY.

164   Detection of Parvalbumin in Various Fish Species by 1D and 2D Electrophoresis and Western Blots Using a Commercially Available Anti-frog Parvalbumin MAb

L. Chen, S. L. Hefle, R. E. Goodman; Food Allergy Research and Resource Program, University of Nebraska-Lincoln, Lincoln, NE.

165   CD4+CD25^high T Regulatory Cells in Egg-Allergic Children Undergoing Oral Desensitization

L. Pons ¹, A. D. Buchanan¹, P. H. Steele¹, H. F. Staats², A. W. Burks¹; ¹Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC, ²Pathology, Duke University Medical Center, Durham, NC.

166   Casein As An “Hidden” Allergen In Manufactured Foods

E. Novembre, C. Caparrelli, F. Mori, C. Calogero, A. Vierucci, M. De Martino; Pediatric Pulmonology and Respiratory Pathophysilogy Hospital Unit, University Children's Hospital, Florence, ITALY.

167   Allergy to Caribou and Seal Meats in Inuit Children: A Report of Three Cases

J. R. Roberts ^1,2, T. V. Gerstner^1,2, D. A. Grewar², D. J. Dilay¹, R. D. Cochrane-Fones¹, T. S. Bouwman¹; ¹Meadowood Medical Centre, Winnipeg, MB, CANADA, ²Pediatrics, University of Manitoba, Winnipeg, MB, CANADA.

168   Timing of Initial Exposure to Cereal Grains and the Risk of Wheat Allergy

J. A. Poole ¹, K. Barriga², D. Y. M. Leung³, M. Hoffman², G. S. Eisenbarth⁴, M. Rewers⁴, J. M. Norris²; ¹Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ²Department of Preventive Medicine and Biometrics, University of Colorado at Denver and Health Sciences Center, Denver, CO, ³Pediatrics, National Jewish Medical and Research Center, Denver, CO, ⁴Barbara Davis Center for Childhood Diabetes, University of Colorado at Denver and Health Sciences Center, Denver, CO.

169   Are Consumer Goods Made from Spun Milk Fibers a Hazard to Milk-Allergic Patients

S. L. Hefle, J. A. Nordlee, D. M. Lambrecht; Food Allergy Research & Resource Program, University of Nebraska, Lincoln, NE.

170   Food Allergy Education for Non-Allergist Physicians: A Needs Assessment Survey

A. Kumar ¹, C. Bruhn², S. S. Teuber¹, S. H. Sicherer³; ¹Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, Davis, CA, ²Food Science and Technology, University of California, Davis, Davis, CA, ³Allergy and Clinical Immunology, Mount Sinai School of Medicine, New York, NY.

171   Identification and Standardization of the Anti Food Allergy Chinese Herbal Formula, FAHF-2, by HPLC Chromatographic Fingerprinting

Y. Chen ¹, Z. Zou¹, D. Chen¹, H. A. Sampson¹, X. Li²; ¹Mt. Sinai, New York, NY, ²Pediatrics, Mt. Sinai, New York, NY.

172   Cloning and Characterization of Walnut Lipid Transfer Protein: Not a Major Allergen in Walnut-Allergic U.S. Patients

S. S. Teuber ¹, E. Pastorello², W. R. Peterson¹, A. M. Dandekar³, S. Uratsu³; ¹Internal Medicine, UC Davis School of Medicine, Davis, CA, ²Internal Medicine and Dermatology, Ospedale Maggiore IRCCS, Milan, ITALY, ³Pomology, UC Davis, Davis, CA.

173   Risk-taking and Coping Strategies of Food Allergic Adolescents and Young Adults

M. Sampson¹, A. Munoz-Furlong², S. H. Sicherer ¹; ¹Pediatrics, Mt Sinai School Of Medicine, New York, NY, ²Food Allergy & Anaphylaxis Network, Fairfax, VA.

174   Continuing Avoidance Diets after Negative Food Challenges

P. A. Eigenmann, J. C. Caubet, S. A. Zamora; Children's University Hospital, Geneva, SWITZERLAND.

175   IgE from Some Green Kiwifruit Allergic Individuals Binds to Proteins in Hardy Kiwifruit, a Third Cultivated Species of the Genus Actinidia

R. E. Goodman ¹, L. Chen¹, J. Lucas², J. O. Hourihane², S. L. Taylor¹; ¹Food Science & Technology, University of Nebraska, Lincoln, NE, ²Allergy and Inflammation Sciences, University of Southampton, Southampton, UNITED KINGDOM.

176   Establishing a Milk Specific IgE Decision Point in IgE Mediated Cow'S Milk Allergy (CMA) Patients from a Tertiary Pediatric Brazilian Center

A. K. F. Gushken, A. P. M. Castro, A. C. Pastorino, E. Ciccone, R. F. F. Gonçalves, C. M. A. Jacob; Department of Pediatrics, University of Sao Paulo, Sao Paulo, BRAZIL.

177   Blackcurrant Allergy

M. Vazquez de la Torre Gaspar; Alergia, Hospital Gregorio Marañon, Madrid, SPAIN.

178   Allergenicity and Antigenicity of Wild-type and Mutant, Monomeric and Dimeric Carrot Major Allergen Dau c 1

G. Reese ¹, A. Wangorsch¹, S. Randow¹, B. K. Ballmer-Weber², S. Vieths¹; ¹Allergology, Paul-Ehrlich-Institut, Langen, GERMANY, ²UniversitätsSpital Zürich, Langen, SWITZERLAND.

179   Seal and Whale Meat: A Newly Recognized Food Allergy

L. M. Moore ¹, J. G. Demain², C. J. Sanner³, B. Whisman¹, M. M. Rathkopf¹; ¹Allergy/Immunology, Wilford Hall Medical Center, Lackland AFB, TX, ²Allergy/Immunology, Allergy, Asthma and Immunology Center of Alaska, LLC, Anchorage, AK, ³U.S. Army Core of Engineers, Anchorage, AK.

180   Germin-like Protein (Cit c 1) And Profilin (Cit s 2) Are Major Allergens In Orange (Citrus sinensis) Fruits

S. Scheurer ¹, M. Retzek¹, K. Fötisch¹, E. Sierra-Maestro², A. B. Cid-Sanchez², C. Y. Pascual², A. Conti³, A. Feliu⁴, J. Rodriguez⁴, S. Vieths¹, J. F. Crespo⁴; ¹Allergology, Paul Ehrlich Institut, Langen, GERMANY, ²Hospital Universitario La Paz, Madrid, SPAIN, ³Proteome Lab, CNR-ISPA, Colleretto Giacosa, ITALY, ⁴Hospital Universitario Doce de Octubre, Madrid, SPAIN.

181   Selective Allergy To Sheep'S And Goat'S Milk Proteins: 4 Cases

A. Vereda ¹, M. A. Sampson², M. Ibanez³, L. Bardina², E. Thanik², H. A. Sampson²; ¹Alergologia, Fundación Jiménez Díaz, Madrid, SPAIN, ²Pediatric Allergy and Immumology, Mount Sinai School of Medicine, New York, NY, ³Alergologia, Hospital Nino Jesus, Madrid, SPAIN.

182   Allergy To Sheep´s And Goat´s Milk Cheese With Good Tolerance to Cow´s Milk

D. Ibañez ¹, G. Gonzalez¹, G. Jimenez¹, C. Escudero¹, T. Laso¹, I. Moneo²; ¹Allergy, Hospital Niño Jesus, Madrid, SPAIN, ²Immunology, Centro de Investigación Clínica y Medicina Preventiva. Instituto de Salud Carlos III, Madrid, SPAIN.

183   Inmediate Reaction after Ingestion of Cooked Mushrooms

C. INMACULADA ¹, R. GARCIA KARMAN¹, A. LOSADA¹, M. DIEGUEZ¹, M. CUEVAS², B. BARTOLOMɳ, B. DE LA HOZ¹, M. SÁNCHEZ CANO¹; ¹ALLERGY, RAMON Y CAJAL, MADRID, SPAIN, ²IMMUNOLOGY, RAMON Y CAJAL, MADRID, SPAIN, ³BIAL-ARISTEGUI, BILBAO, SPAIN.

184   Sunflower Seed Allergy

S. I. Hungness, A. M. Singer, J. L. Baldwin; Division of Allergy and Immunology, University of Michigan, Ann Arbor, MI.

185   Usefulness of Diagnostic Tests in Cows’ Milk Allergy

I. CERECEDO ¹, M. DIEGUEZ¹, A. MURIEL², A. GARCIA BALDA¹, S. TERRADOS¹, M. SANCHEZ CANO¹, B. DE LA HOZ¹; ¹ALLERGY, RAMON Y CAJAL, MADRID, SPAIN, ²Unidad de bioestadistica, RAMON Y CAJAL, MADRID, SPAIN.

186   Cas S 8, the Lipid Transfer Protein from Chestnut Seeds, is a Major Allergen in Chestnut Allergic Patients without Associated Latex Allergy, but not in those with the Latex-Fruit Syndrome

C. Blanco ¹, R. Sánchez-Monge², M. Recas², G. López-Torrejón², J. Cumplido¹, J. Figueroa¹, T. Carrillo¹, G. Salcedo²; ¹Hospital Universitario Dr. Negrín, Las Palmas de GC, SPAIN, ²E.T.S. Ingenieros Agrónomos, Madrid, SPAIN.

187   Sensitization to Non-Specific Lipid Transfer Protein from Parietaria Judaica Pollen and Cross Sensitization to Foods

M. Ibero ¹, M. Castillo¹, M. Viñas¹, B. Bartolomé²; ¹Unitat d'Al·lèrgia, Hospital de Terrassa, Terrassa, SPAIN, ²I + D, Laboratorios BIAL-Aristegui, Bilbao, SPAIN.

188   Analysis of Ag-specific Ige Antibody, Total Serum Ige and Blood Eosinophil in Food Allergic Children

J. Kim ¹, Y. Kim², H. Lee²; ¹Department of Pediatrics, Catholic University Medical College, Uijongbu-city, REPUBLIC OF KOREA, ²Department of Clinical Pathology, Catholic University Medical College, Uijongbu-city, REPUBLIC OF KOREA.

189   A Survey of Treatment and Referral of Food Allergy Cases by Primary Care Physicians in San Diego County

M. S. Wolf¹, B. M. Prenner ²; ¹UC Berkeley, Berkeley, CA, ²UCSD Associate Clinical Professor, La Jolla, CA.

190   Scurvy Associated with Oral Allergy Syndrome

A. Des Roches ¹, L. Paradis², J. Paradis², M. Masse², S. Singer¹;

¹Allergy-immunology, Hôpital Sainte-Justine, Montréal, PQ, CANADA, ²Allergy-immunology, CHUM, Pavillon St-Luc, Montréal, PQ, CANADA.

191   Angioedema and Urticaria Caused by Sliced Soft Bread

A. Enriquez-Matas ¹, S. Quirce¹, M. Fernández-Nieto¹, C. Pastor², M. de las Heras¹, J. Sastre¹; ¹Allergy Department, Fundación Jimenez Díaz, Madrid, SPAIN, ²Immunology Department, Fundación Jimenez Díaz, Madrid, SPAIN.

192   Cow's Milk Protein Allergy in Thai Children

P. Tansupapol; Pediatrics, King Chulalongkorn Memorial Hospital, Bangkok, THAILAND.

193   Secretion of Food Allergen Proteins in Saliva

S. J. Maleki ¹, H. Cheng¹, B. Perelman², S. Hefle³, P. Vadas²; ¹Food Allergy Unit, USDA-Agricultural Research Service, New Orleans, LA, ²Immunology and Allergy, St. Michael's Hospital, Toronto, ON, CANADA, ³Department of Food Science & Technology, University of Nebraska, Lincoln, NE.

194   IgE Cross-reactivity between the Cysteine Proteases Der p 1 and Act c 1, the Major Allergens from House Dust Mites and Kiwifruit

B. Merima ¹, C. Radauer¹, C. Ebner², D. Allwardth¹, W. R. Thomas³, A. Mari⁴, A. Knulst⁵, O. Scheiner¹, H. Breiteneder¹; ¹Department of Pathophisiology, Medical University Vienna, Vienna, AUSTRIA, ²Allergieambulatorium Reumanplatz, Vienna, AUSTRIA, ³Division of Molecular Biology, TVW Telethon Institute for Child Health Research, West Perth, AUSTRALIA, ⁴National Health Service, Rome, ITALY, ⁵Department of Dermatology/Allergology, University Medical Center, Utrecht, THE NETHERLANDS.

195   Allergenic Fruit TLPs Possess Different Degrees of IgE Cross-reactivity

U. Smole ¹, M. Bublin¹, C. Radauer¹, C. Ebner², O. Scheiner¹, H. Breiteneder¹; ¹Dept. of Pathophysiology, Medical University of Vienna, Vienna, AUSTRIA, ²Allergieambulatorium Reumannplatz, Vienna, AUSTRIA.

196   IgE-Reactive Proteins in Cashew Apple Juice Concentrate are Removed by Filtration

S. S. Comstock ¹, H. Kshirsagar², J. M. Robotham³, K. H. Roux³, S. K. Sathe², S. S. Teuber¹; ¹Internal Medicine, University of California, Davis, Davis, CA, ²Nutrition, Food and Exercise Sciences, Florida State University, Tallahassee, FL, ³Biological Science, Florida State University, Tallahassee, FL.

197   Outcomes of Oral Food Challenge with Undetectable Allergen-Specific IgE

S. Desai, L. Kerns, R. Seshadri, J. A. Pongracic; Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL.

198   Using Human Basophil Donors to Assess the Clinical Relevance of Sesame 11S Globulin, Ses i 6

M. L. Wallowitz ¹, R. J. Y. Chen², J. T. C. Tzen², S. S. Teuber¹; ¹Division of Rheumatology, UC Davis, Davis, CA, ²Graduate Institute of Agricultural Biotechnology, National Chung-Hsing University, Taichung, TAIWAN REPUBLIC OF CHINA.

199   Evaluation of Food-Allergen Specific IgE in Hyper-IgE Sera

J. Popov, Q. Nguyen, L. Londono, A. Sferruzza, M. Glovsky; Immunology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA.

200   Parvalbumin was Not Responsible for the Cross-Reactivity between Tuna and Marlin: A Case Report

Y. Kondo ¹, R. Komatsubara¹, Y. Nakajima¹, M. Kawamura¹, M. Kakami¹, I. Tsuge¹, T. Yasuda², A. Urisu¹; ¹Pediatrics, Fujita Health University, Toyoake, Aichi, JAPAN, ²Toyo Suisan Kaisha, Ltd, Tokyo, JAPAN.

201   Analysis of Placebo Reactions in Double-Blind, Placebo-Controlled Food Challenge Tests in Children

B. J. Vlieg-Boerstra ¹, S. van der Heide², J. Kukler¹, C. M. A. Bijleveld¹, B. J. Beusekamp³, E. J. Duiverman¹, A. E. J. Dubois⁴;

¹Dept. of Paediatrics, University Medical Center Groningen, University of Groningen, Groningen, THE NETHERLANDS, ²Dept. of Allergology, University Medical Center Groningen, University of Groningen, Groningen, THE NETHERLANDS, ³Dept. of Dietetics, University Medical Center Groningen, University of Groningen, Groningen, THE NETHERLANDS, ⁴Dept of Allergology and Dept of Paediatrics, University Medical Center Groningen, University of Groningen, Groningen, THE NETHERLANDS.

202   Physician Advice and Action Plans in Severe Food Allergy

J. S. W. Kong ¹, L. A. D. Haapanen¹, L. J. Phillipo², C. M. Bruhn², S. S. Teuber¹; ¹Rheumatology, Allergy, and Clinical Immunology, University of California at Davis, Davis, CA, ²Food Science and Technology, University of California at Davis, Davis, CA.

203   Tropomyosin: Is it Responsible for the Cross-Reactivity Crustaceans-Dust Mites

A. Mendes, M. C. Santos, E. Pedro, M. A. Pereira-Barbosa; Unidade Imunoalergologia, Hospital Santa Maria, Lisboa, PORTUGAL.

204   Treatment of Pregnant Females with Anti-Acids Induces Sensitization in Mothers and a Perinatal Th2-Dominated Immune Response in Offsprings: a BALB/c Mouse Model

I. Schöll ¹, U. Ackermann², C. Özdemir³, N. Blümer², T. Dicke², S. Sel², S. Sel², M. Wegmann², E. Untersmayr¹, H. Garn², E. Jensen-Jarolim¹, H. Renz²; ¹Center of Physiology and Pathophysiology, Inst. of Pathophysiology, Vienna, AUSTRIA, ²Hospital of the Philipps-University Marburg, Dept. of Clinical Chemistry and Molecular Diagnostics, Marburg, GERMANY, ³School of Medicine Marmara University, Pediatric Allergy and Immunology Division, Istanbul, TURKEY.

205   Case Reports of Seed Anaphylaxis: Mustard, Flax and Sunflower Seed

L. A. Connors ¹, W. H. Yang², G. A. Lacuesta¹; ¹Dalhousie University, Halifax, NS, CANADA, ²University of Ottawa, Ottawa, ON, CANADA.

Poster Session

2209

Saturday, March 04, 2006

9:45 am to 10:45 am

Underserved Populations

206   Coping with Asthma in Immigrant Hispanic Families: A Focus Group Study

G. S. Mosnaim ^1,2, C. Kohrman³, L. K. Sharp⁴, M. E. Wolf⁵, L. S. Sadowski⁶, L. Ramos⁷, L. Grammer⁸; ¹Department of Immunology and Microbiology, Rush University Medical Center, Chicago, IL, ²Division of Allergy and Immunology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL, ³Community Research and Training Consultant, Chicago, IL, ⁴Department of Family Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵International Neuropsychiatry Consultants, Chicago, IL, ⁶Department of Medicine Collaborative Research Unit, Cook County Bureau of Health Services, Chicago, IL, ⁷Centro San Bonifacio, Chicago, IL, ⁸Department of Medicine, Division of Allergy and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL.

207   Cultural Perceptions on Identification and Treatment of Childhood Asthma in the US and China

H. L. Leo, A. Wang, M. Gong, N. Clark; School of Public Health, University of Michigan, Ann Arbor, MI.

208   A Community Based Approach to Reducing Hispanic Pediatric Asthma Disparities: A Collaborative Effort to Deliver Care between a Bicultural Bilingual Allergist/Immunologist (BC/BL/A/I)and Community Health Workers (CHWs)

J. J. Kulik ^1,2, L. G. Hwang¹, C. A. Jackson¹, J. Mora¹, J. N. Moy^1,2, G. S. Mosnaim^1,2; ¹Allergy and Immunology, Rush University Medical Center, Chicago, IL, ²Allergy and Immunology, Stroger Hospital of Cook County, Chicago, IL.

209   Health Status and Functional Limitations in Elderly vs Younger Patients with Asthma, Diabetes, or Hypertension: An analysis of the Medical Expenditure Panel Survey.

J. Chang¹, J. Sung², D. Gause², G. P. Geba ³; ¹Duke Clinical Research, Durham, NC, ²Health Economics and Outcomes Research, Novartis Pharmaceuticals Corp., E Hanover, NJ, ³USCDMA, Novartis Pharmaceuticals Corp., E Hanover, NJ.

210   Using CBPR to Recruit Physicians and Develop Partnerships with Community Clinics for Asthma Disparities Research

D. P. Williams, R. I. Quartey; Epidemiology, Howard University College of Medicine, Washington, DC.

211   Communication between Educators and Parents of Asthmatic Children Improves Academic and Medical Outcomes in Beijing and Detroit

H. L. Leo, A. Wang, M. Gong, N. Clark; School of Public Health, University of Michigan, Ann Arbor, MI.

212   Stories of Four Women with Asthma in an Inner City Clinic Setting: A Narrative Analysis

L. A. Martin; The Mount Sinai Hospital, New York, NY.

Poster Session

2210

Saturday, March 04, 2006

9:45 am to 10:45 am

Asthma Education

213   A Content Analysis of Web-Based Expert Forum on Asthma and Allergy

K. Sade ¹, Y. Levo², S. Kivity¹; ¹Allergy & Asthma, Tel-aviv Sourasky Medical Center, Tel-aviv, ISRAEL, ²Internal Medicine “T”, Tel-aviv Sourasky Medical Center, Tel-aviv, ISRAEL.

214   Increasing Long-Term Control Medication Usage Among Children with Asthma

V. K. Owen ¹, L. M. Morris², A. D. Robinson¹; ¹Anthem BCBS, Mason, OH, ²Anthem RX Service, Mason, OH.

215   Impact of an Asthma Educational Program on Children at an Asthma Camp

A. T. Vu ¹, M. C. Glaum¹, E. G. Naik¹, M. Grandstaff², M. N. Shah¹, P. Panagos¹, R. Franck¹, J. T. Ramey¹, R. F. Lockey¹; ¹University of South Florida - College of Medicine and James A. Haley Veterans’ Hospital, Tampa, FL, ²University of South Florida - Clinical Research Unit, Tampa, FL.

216   Primary Care Provider (PCP) Asthma Communication and Quality of Asthma Care

K. A. Riekert ¹, B. Kalesan¹, A. M. Butz², M. E. Bollinger³, K. Walton¹, K. Mudd³, C. S. Rand¹; ¹Medicine, Johns Hopkins University, Baltimore, MD, ²Pediatrics, Johns Hopkins University, Baltimore, MD, ³Pediatrics, University of Maryland, Baltimore, MD.

217   Teaching with Style: Utilizing Active Learning Strategies in Asthma and Allergy Education

D. S. Clark; Stafford County Schools, Stafford, VA.

Poster Session

2211

Saturday, March 04, 2006

9:45 am to 10:45 am

Eosinophils and Neutrophils

218   Eotaxin-1 & -2 Induced Migration of CD34+/CCR3+ Bone marrow and Blood Eosinophil-lineage Committed Cells

J. Lötvall ¹, A. Bossios¹, M. Sjöstrand¹, J. J. Lee², M. Rådinger¹; ¹Dept. of Respiratory Medicine and Allergology, Lung Pharmacology Group, Göteborg University, Göteborg, SWEDEN, ²Divison of Pulmonary Medicine, Mayo Clinic, Scottsdale, AZ.

219   Effect of Cysteinyl Leukotrienes on Eosinophilopoiesis during the Onset of Asthma

P. R. Ogershok ¹, D. Piktel², K. S. Landreth², M. B. Hogan¹; ¹Pediatrics, West Virginia University School of Medicine, Morgantown, WV, ²Immunology, West Virginia University School of Medicine, Morgantown, WV.

220   CpG Oligodeoxynucleotide Prolongs Human Eosinophil Survival through Activation of B Cells or Plasmacytoid Dendritic Cells in vitro

K. Matsumoto ¹, S. Fukuda¹, M. Terakawa^1,2, A. Kato¹, H. Saito¹;

¹Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN, ²Daiichi Suntory Pharma Co. Ltd., Osaka, JAPAN.

221   Eosinophils do Not Modify Trans-Basement Membrane Migration of Neutrophils

T. Kobayashi, I. Kikuchi, K. Hagiwara, M. Kanazawa, M. Nagata; Department of Respiratory Medicine, Saitama Medical School, Saitama, JAPAN.

222   Aeroallergen Sensitization in Children with Eosinophilic Esophagitis

J. M. Norvell, D. Hummell; Department of Medicine, Vanderbilt University, Nashville, TN.

223   Dipeptidyl-Peptidase IV Modulates CCL11/Eotaxin-Induced Mobilization and Recruitment of Eosinophils

U. Forssmann; Pharmacology, IPF Pharmaceuticals, Hannover, GERMANY.

224   A Novel Model of Transgene-Induced Eosinophilic Esophagitis

C. Fischetti, P. Fulkerson, M. Rothenberg; Cincinnati Children's Hospital, Cincinnati, OH.

225   Anti-IL-5 Therapy (Mepolizumab) in Hypereosinophilic Syndromes and Eosinophilic Esophagitis: Cytokine Secretion and Decreased Peripheral Blood Eosinophilia

M. L. Stein ¹, J. M. Villanueva², S. C. Jameson¹, B. Buckmeier¹, A. H. Filipovich², M. H. Collins³, Y. Yamada¹, A. H. Assa'ad¹, M. E. Rothenberg¹; ¹Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Hematology/Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

226   Newly Produced Eosinophil-Lineage Committed Cells Proliferate in the Lung of Allergen-Challenged Mice

M. Rådinger, A. Bossios, M. Sjöstrand, J. Lötvall; Dept. of Respiratory Medicine and Allergology, Lung Pharmacology Group, Göteborg University, Gothenburg, SWEDEN.

227   CD30-Induced Apoptosis of Human Blood Eosinophils is Mediated by Nitric Oxide Production and JNK Pathway Activation

A. I. Berro, D. K. Agrawal; Center for Allergy, Asthma, and Immunology, Creighton University, Omaha, NE.

228   Osteopontin (Opn) is Expressed and Functional in Human Peripheral Blood Eosinophils

I. Puxeddu ¹, D. Ribatti², R. Bader³, N. Berkman³, F. Levi-Schaffer¹; ¹Hebrew University of Jerusalem, Jerusalem, ISRAEL, ²University of Bari, Bari, ITALY, ³Hadassah-Hebrew University Medical Center, Jerusalem, ISRAEL.

229   Urokinase-type Plasminogen Activator (uPA) Primes FMLP-Activated Airway Eosinophil (EOS) Adhesion to ICAM-1 and VCAM-1 Following Segmental Bronchoprovocation with Allergen (SBP-AG)

A. M. Brooks, J. B. Sedgwick; Medicine, University of Wisconsin, Madison, WI.

230   15d-PGJ2 Primes Eotaxin-induced Eosinophil Chemotaxis Through PPAR-Gamma Ligation

S. Ueki ¹, Y. Kobayashi², G. Mahemuti², T. Chiba², N. Saito², A. Kanda², H. Kayaba², K. Ohta¹, J. Chihara²; ¹Department of Internal Medicine, Teikyo University School of Medicine, Itabashi-ku, JAPAN, ²Depertment of Clinical and Laboratory Medicine, Akita University School of Medicine, Akita, JAPAN.

231   Phosphoproteomic Profiling of Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)-Dependent Activation of Human Eosinophils

T. W. Young ¹, K. Pazdrak¹, S. Stafford¹, A. Brasier², J. Wiktorowicz¹, H. Spratt¹, A. Kurosky¹; ¹Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston, TX, ²Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX.

232   Exaggerated Airway Wall Eosinophilia and Physiologic Dysfunction in Asthma-like Airways after Chronic Alternaria Exposure in Rats

R. L. Sorkness ¹, K. M. Herricks¹, R. J. Szakaly², R. F. Lemanske, Jr.², L. A. Rosenthal²; ¹School of Pharmacy, University of Wisconsin, Madison, WI, ²Medicine, University of Wisconsin, Madison, WI.

233   Systemic Effects of Chronic Asthma on Bone Marrow Eosinophil Development

M. B. Hogan ¹, D. Piktel¹, A. F. Hubbs², L. McPherson², K. S. Landreth¹; ¹West Virginia University, Morgantown, WV, ²NIOSH, Morgantown, WV.

234   Molecular Markers of Eosinophilopoiesis at Birth: Kinetics of Cord Blood GATA-1, MBP and IL-5 Receptor Expression

A. K. Ellis, L. Crawford, J. A. Denburg; Division of Allergy & Clinical Immunology, McMaster University, Hamilton, ON, CANADA.

235   Urokinase-type Plasminogen Activator (uPA) Primes Eosinophil (EOS) Chemotaxis

J. B. Sedgwick, E. A. Durocher, A. M. Brooks; Department of Medicine, University of Wisconsin - Madison, Madison, WI.

236   A Role for the Ectoenzyme, CD38, in Human Eosinophil Functions

T. A. White, Y. Matsuwaki, H. Kita; Mayo Clinic, Rochester, MN.

237   House Dust Mite Extract Induces Interleukin-9 Expression in Human Eosinophils.

H. Katsumata ^1,2, Y. Kato¹, T. Fujisawa¹; ¹Institute for Clinical Research, Mie National Hospital, Tsu, JAPAN, ²Allergy, Immunology and Infectious diseases, Shizuoka Children's Hospital, Shizuoka, JAPAN.

238   Neurotrophins Produced by Airway Epithelial Cells Promote the Survival of Eosinophils During Allergic Asthma

C. Hahn, A. Pyraesh, H. Renz, W. A. Nockher; Department of Clinical Chemistry and Molecular Diagnostics, Medical Faculty of the Philipps University, Marburg, GERMANY.

239   Association of Tumor Necrosis Factor-a and Neutrophilic Inflammation in Severe Asthma

M. Nagata, S. Kikuchi, I. Kikuchi, K. Hagiwara, M. Kanazawa; Department of Respiratory Medicine, Saitama Medical School, Saitama, JAPAN.

240   Eosinophilic Oophoritis

J. H. Butterfield ¹, G. M. Kephart¹, J. Frankson²; ¹Mayo Clinic, Rochester, MN, ²Marshfield Clinic, Wausau, WI.

241   Human Eosinophils Enhance Staphylococcal Enterotoxin B Stimulation of CD4⁺ T-cells

S. K. Mathur, E. A. Durocher, L. Liu, E. A. B. Kelly, J. B. Sedgwick, N. N. Jarjour, W. W. Busse; University of Wisconsin, Madison, WI.

242   Lymphocytic Infiltrates in Eosinophilic Gastroenteropathy

S. J. McGeady; Pediatrics, Thomas Jefferson University, Philadelphia, PA.

243   The Effect of Lipopolysaccharide (LPS) on Cord Blood (CB) Hemopoietic Progenitor Cytokine Receptor Expression

M. M. Cyr, F. Bandukwala, J. A. Denburg; Medicine, McMaster University, Hamilton, ON, CANADA.

244   A Case of Eosinophilia

C. C. Hassett, A. Kewalramani, L. Wild, D. DeMerell; Clinical Immunology, Allergy and Rheumatology, Tulane University Health Science Center, New Orleans, LA.

245   Rexflavon Inhibits Eosinophil Recruitement And Bronchial Reactivity In Mice Asthma Model

M. Kim ¹, Y. Kim², C. Hahn¹, H. Sung³; ¹Internal Medicine, Chungbuk National University, Cheongjoo, REPUBLIC OF KOREA, ²College of Pharmacy, Chungbuk National University, Cheongjoo, REPUBLIC OF KOREA, ³College of pharmacy, Chungbuk National University, Cheongjoo, REPUBLIC OF KOREA.

246   Macrophage Derived Non-Specific Esterase and Allergen Stimulation

D. R. Howell ¹, T. Hackett¹, W. C. Moore², J. A. Warner¹; ¹School of biological sciences, Southampton University, Southampton, UNITED KINGDOM, ²Medicine, Wake forest University, Winston-Salem, NC.

247   Demographics and Risk Factors for Eosinophilic Esophagitis

L. R. Tuchman ¹, J. M. Spergel^2,3; ¹University of Pennsylvania, Philadelphia, PA, ²Division of Allergy and Immunology, University of Pennsylvania, Philadelphia, PA, ³Divison of Allergy and Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA.

248   Utility of Anti-parasite Antibodies in the Differential Diagnosis of Chronic Hypereosinophilia

B. G. Wilson, P. B. Boggs, C. Mayer; Section of Allergy & Immunology, Louisiana State University-Shreveport, Shreveport, LA.

249   Comparison of Leukolysin/MT6-MMP in Bronchoalveolar Lavage Fluid from Lung Transplant Patients and Asthmatics

J. P. Raasch ¹, C. L. Liebeler¹, C. H. Wendt¹, J. B. Sweet¹, N. N. Jarjour², R. S. DeGrauw², D. Pei³, M. N. Blumenthal¹; ¹Pulmonology, Allergy and Critical Care, University of Minnesota, Minneapolis, MN, ²Pulmonology, University of Wisconsin, Madison, WI, ³Pharmacology, University of Minnesota, Minneapolis, MN.

250   Prevalence and Causes of Moderate-Severe Eosinophilia in Children

N. Segal, Y. Levy, B. Garty, Y. L. Danon; Scneider Children Medical Center of Israel, Petah Tikva, ISRAEL.

251   Direct Interaction of Recombinant Human Surfactant Protein-D (rhSP-D) Modulates Human Eosinophil Activation, Their Rate of Apoptosis and Clearance by Macrophages

L. Mahajan ¹, S. D. Telang², U. Kishore³, V. K. Singh⁴, C. N. Ramchand⁵, P. U. Sarma⁶, T. Madan¹; ¹Institute of Genomics and Integrative Biology, Delhi, INDIA, ²Department of Biochemistry, M.S. University of Baroda, Vadodara, INDIA, ³Weatherall Institute of Molecular Medicine, Oxford, UNITED KINGDOM, ⁴V,P, Chest Institute, Delhi, INDIA, ⁵Kemin Nutritional Technologies, Tamilnadu, INDIA, ⁶Indian Agriculture Research Institute, Pusa, Delhi, INDIA.

Poster Session

2212

Saturday, March 04, 2006

9:45 am to 10:45 am

Mast Cells and Basophils

252   Estradiol Enhances the Release of Allergic Mediator from Bone Marrow-derived Mast Cells (BMMCs) Via Estrogen Receptor a (ERa)

S. Narita, R. M. Goldblum, C. K. Lambert, M. Zaitsu, M. D. Estes, E. G. Brooks, T. Midoro-Horiuti; Pediatrics, UTMB, Galveston, TX.

253   Alpha 4 Integrins and VCAM-1, but not MAdCAM-1, are Essential for Recruitment of Mast Cell Progenitors to Inflamed Lung

M. F. Gurish ¹, J. Hallgren¹, T. Jones¹, J. Boyce¹, J. Abonia²; ¹Rheumatology, Immunology, Allergy, Brigham and Women's Hospital, Boston, MA, ²Pediatric Allergy and Immunology, Cincinnati Children's Hospital, Cincinnati, OH.

254   Expression of Neuropilin-1 (NP-1) on Human Basophils Following In Vitro IL-3 Exposure: Implications for NP-1 as a Marker of Basophil Priming

J. T. Schroeder, A. P. Bieneman, M. C. Liu; Department of Medicine, Johns Hopkins University, Baltimore, MD.

255   Human Mast Cells Express Neurokinin and Vasoactive Intestinal Peptide Receptors

M. Kulka, C. Sheen, S. Toth, B. P. Tancowny, L. C. Grammer, R. P. Schleimer; Allgery-Immunology Division, Northwestern University Feinberg Sch. Med., Chicago, IL.

256   Human Hematopoietic PGD₂ Synthase: Inhibition by 15-deoxy--^12,14-PGJ₂ and Sulindac Sulfide, and Localization to Mast Cells

G. M. Greig, F. Masse, F. Nantel, A. Chateauneuf, G. O'Neill, G. O'Neill; Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Kirkland, PQ, CANADA.

257   Mast Cell-Derived Plasminogen Activator Inhibitor-1 in the Airways of a Murine Asthma Model and Its Regulation by Cysteinyl Leukotrienes

S. H. Cho ¹, J. A. Boyce², T. J. Yoo¹, C. K. Oh³; ¹Internal Medicine, University of Tennessee HSC, Memphis, TN, ²Internal Medicine, Brigham and Women's Hospital, Boston, MA, ³Pediatrics, Harbor-UCLA Medical Center, Torrance, CA.

258   TLR3 Stimulation Enhanced FceRI -Mediated MIP-1a Production from Cultured Human Mast Cells

H. Tachimoto, S. Sato, Y. Yanagihara, M. Ebisawa; Department of Pediatrics, National Hospital Organization, Sagamihara National Hospital, Kanagawa, JAPAN.

259   Human Lung Mast Cells Express the Orphan G-Protein Receptor GPR80/GPR99

H. Nishi, P. Amir, E. S. Schulman; Pulmonary and Critical Care Medicine, Drexel University College of Medicine, Philadelphia, PA.

260   Serotonin Induces Mast Cell Adhesion and Chemotaxis through the 5-HT1A Receptor

N. M. Kushnir-Sukhov ¹, A. M. Gilfillan¹, J. W. Coleman¹, M. Toth², S. Bruening², D. D. Metcalfe¹; ¹Laboratory of Allergic Diseases, NIH/NIAID, Bethesda, MD, ²Department of Pharmacology, Weill Medical College of Cornell University, New York, NY.

261   Development of Tryptase and Chymase Double Positive Mature Mast Cells from Cynomolgus Monkey Embryonic Stem Cells

N. Kambe ¹, F. Ma², Y. Miyachi¹, T. Nakahata²; ¹Dermatology, Kyoto University, Kyoto, JAPAN, ²Pediatrics, Kyoto University, Kyoto, JAPAN.

262   Distinct Basophil Functional Phenotypes in Chronic Idiopathic Urticaria (CIU)

L. M. Gober, N. U. Ohameje, K. Vasagar, B. M. Vonakis, S. S. Saini; Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD.

263   Human Mast Cells Release Oncostatin M (OSM) Specifically on Contact with Activated T Cells

P. Salamon¹, N. Shoham¹, I. Puxeddu², F. Levi-Schaffer², Y. A. Mekori ¹; ¹Medicine B, Meir Hospital, Kfar-Saba, ISRAEL, ²Pharmacology, Hebrew University, Jerusalem, ISRAEL.

264   Vespid Venom-Induced IL-4- and IL-13-Production of Basophils is Inhibited By IL-10

C. Bauer, J. Walter, F. Ruëff, B. Przybilla; Ludwig-Maximilians-Universität München, Klinik und Poliklinik für Dermatologie und Allergologie, München, GERMANY.

265   CysLT1 and CysLT2 Receptors Form Functional Heterodimers on Human Mast Cells and Neutrophils

Y. Jiang, J. Boyce; Medicine, Brigham and Women's Hospital, Boston, MA.

266   Neuropeptides Activate Human Mast Cell Degranulation and Chemokine Production

B. P. Tancowny, C. Sheen, L. C. Grammer, R. P. Schleimer, M. Kulka; Allergy-Immunology, Northwestern University Feinberg Sch. Med., Chicago, IL.

267   Opiates Activate Human Mast Cell Chemokine Production

C. Sheen, L. C. Grammer, R. P. Schleimer, M. Kulka; Allgery-Immunology Division, Northwestern University Feinberg Sch. Med., Chicago, IL.

268   Antigen-Induced Production of S1P Leads to Cell Migration Independently of S1P Receptor in RBL-2H3 Cells

I. JUNG, O. H. CHOI; JHAAC, Johns Hopkins University, Baltimore, MD.

269   Analysis of Global Protein Content in Mast Cell Exosomes

K. Ekström, H. Valadi, N. Almqvist, A. Bossios, M. Sjöstrand, J. Lötvall; Lung Pharmacology Group. Dept. of Resp. Med and Allergol, Göteborg, SWEDEN.

270   Carboxypeptidase as a Marker of Mast Cell Heterogeneity in Human Tissues

M. G. Buckley, S. He, Y. He, S. Goda, J. Gelnar, A. F. Walls; Immunopharmacology Group, University of Southampton, Southampton, UNITED KINGDOM.

271   Rate of Negativization of the Basophil Activation Test (BASOTEST) and RAST in Patients with Immediate Allergic Reactions to Amoxicillin

T. D. Fernandez¹, M. J. Torres², C. Mayorga¹, E. Martin², J. L. Rodriguez-Bada¹, C. Antunez¹, N. Blanca², J. A. Cornejo-Garcia¹, M. Blanca ²; ¹Research Laboratory, Carlos Haya Hospital, Malaga, SPAIN, ²Allergy Service, Carlos Haya Hospital, Malaga, SPAIN.

272   Examination of Toxicological Effects of Aldehyde Air Pollutants on Mast Cells (RBL-2H3)

D. J. Hochman ¹, C. Collaco², E. G. Brooks²; ¹Experimental Pathology, University of Texas Medical Branch, Galveston, TX, ²Pediatrics, University of Texas Medical Branch, Galveston, TX.

273   Gene Expression Profiling of Human Mast Cell Subtypes

H. Saito ^1,2, K. Matsumoto^1,2, Y. Okayama²; ¹Department of Allergy & Immunology, National Research Institute for Child Health & Development, Tokyo, JAPAN, ²Research Unit for Allergy Transcriptome, RIKEN Research Center for Allergy & Immunology, Yokohama, JAPAN.

274   Management of Type II Systemic Mastocytosis (SM-AHNMD) with Hydroxyurea

J. Sheikh ¹, R. E. Drews¹, R. Nunez², A. G. Montero³, M. Jara³, A. Orfao³, L. Escribano²; ¹Medicine, Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, ²Mast Cell Unit, Hospital Ramon y Cajal, Madrid, SPAIN, ³Servicio de Citometría, CIC, Salamanca, SPAIN.

275   Regulation by Complement of the Release of Basophil Mediators in Asthmatic Patients

M. C. Nelson, S. K. Wust, B. A. Benson, M. N. Blumenthal, A. P. Dalmasso; University of Minnesota, Minneapolis, MN.

276   Protocol for in vitro Desensitization of Human Basophils that Mimics the Up Dosing Approach used in SCIT - Monitored Measuring CD63 and CD203c Activation Markers

G. Lund, H. Jacobi, J. Holm, K. Lund; Research Department, ALK-ABELLÓ A/S, Hørsholm, DENMARK.

Poster Session

2213

Saturday, March 04, 2006

9:45 am to 10:45 am

Rhinosinusitis Mechanisms

277   Detection of Staphylococcus Aureus by Real-Time PCR in Chronic Rhinosinusitis with Nasal Polyps

A. Tripathi ¹, B. Tancowny¹, Q. Truong-Tran¹, S. Retsema², R. Kern², D. Conley², L. Suh¹, R. Schleimer¹, L. Grammer¹; ¹Medicine, Northwestern University Medical School, Chicago, IL, ²Otolaryngology - Head and Neck Surgery, Northwestern University Medical School, Chicago, IL.

278   The Association of Total IgE and Specific IgE Anti-Staphylococcal Enterotoxin with Chronic Hyperplastic Rhinosinusitis

P. S. Hutcheson ¹, D. A. Oliver², M. S. Schubert³, R. G. Slavin¹; ¹Internal Medicine/Allergy & Immunology, Saint Louis University School of Medicine, Saint Louis, MO, ²Cancer Center, Saint Louis University School of Medicine, Saint Louis, MO, ³Allergy Asthma Clinic, Ltd., Phoenix, AZ.

279   Aspirin-induced 15-HETE Generation in Nasal Polyp Tissue from Aspirin-Sensitive Patients

M. L. Kowalski ¹, A. Lewandowska-Polak¹, M. Jedrzejczak¹, A. Jankowski²; ¹Department of Clinical Immunology and Allergy, Medical University of Lodz, Lodz, POLAND, ²Department of Otorhinolaryngology, Medical University of Lodz, Lodz, POLAND.

280   Nares: Local Cytokine Pattern in Nasal Secretions

C. Klemens, D. Liebl, E. Pfrogner, F. Jund, M. Kramer; Klinikum Grosshadern, Oto-Rhino-Laryngology, Head and Neck Surgery, Ludwig-Maximilians-University Munich, Munich, GERMANY.

281   Local Activation of the Complement System in Nasal Polyps.

T. Van Zele, G. Holtappels, P. Van Cauwenberge, C. Bachert; ENT department 1P1, University hospital of Ghent, Gent, BELGIUM.

282   Characterization of Responses of Human Nasal Epithelial Cells to Pro-inflammatory Mediators and Secretagogues

J. L. Stahl, E. B. Cook, F. M. Graziano; Medicine, University of Wisconsin-Madison, Madison, WI.

283   Ultrastructural Findings In Patients with Allergic Rhinitis

S. Knipping; ENT Department, Martin Luther University, Halle/ Saale, GERMANY.

284   Relationship Between Promoter Methylation of Multiple Genes and inflammatory Cell infiltration in Nasal Polyps

c. li ¹, Y. Pang¹, Q. Tao², D. Wang¹; ¹Otolaryngology, National University of Singapore, Singapore, SINGAPORE, ²Chinese University of Hong Kong, Hong Kong, CHINA.

285   Unique Genetic Expression in Nasal Mucosa and Blood of Patients with Nasal Polyposis and Inflammatory Nasal Conditions

T. A. Miller ¹, J. Kukowska-Latallo², A. M. Singer¹, M. A. Pynnonen³, J. E. Terrell³, J. R. Baker, Jr.⁴; ¹Department Of Internal Medicine, Division of Allergy & Clinical Immunology, University of Michigan Health System, Ann Arbor, MI, ²Michigan Nanotechnology Institute for Medicine & Biological Sciences, University of Michigan, Ann Arbor, MI, ³Department Of Otolaryngology, University of Michigan Health System, Ann Arbor, MI, ⁴Michigan Nanotechnology Institute for Medicine & Biological Sciences, University of Michigan Health System, Ann Arbor, MI.

286   Heterogeneity of Effects in the Appearance of Rhinitis and/or Asthma According to Gender and Atopy

M. A. Tejedor, A. Rosado, C. Vila, M. Moro, M. D. Alonso, M. Mugica, M. Fernández-Rivas, T. Verdura; Unidad de alergia, FUNDACION HOSPITAL ALCORCON, ALCORCON, SPAIN.

287   Hypoxic Induction of Inflammatory Responses in Chronic Sinusitis

J. W. Steinke, S. B. Early, K. Hise, L. Borish; Asthma and Allergic Diseases Center, University of Virginia, Charlottesville, VA.

288   Nasal Eosinophilia in Infants with Atopic Dermatitis

K. A. DeMuth ¹, W. Zhao², C. Koenig², D. Mitchell², A. Irani²; ¹Allergy-Immunology, Washington University in St. Louis, St. Louis, MO, ²Allergy-Immunology, Virginia Commonwealth University, Richmond, VA.

289   Risk Factors for Bronchial Hyperresponsiveness in Children with Allergic Rhinitis

J. Kim; Pediatrics, Inha University Hospital, Incheon, REPUBLIC OF KOREA.

290   Asthma and Allergic Rhinitis in Patients with Beta-Thalassemia Minor

L. Palma-Carlos, A. G. Palma-Carlos; Allergy, CAIC - Clinical Allergy Immunology Center, Lisbon, PORTUGAL.

291   Breathe Right Strips(R) (BRS) Improve Respiratory Index (RI) in Patients with Rhinitis and Obstructive Sleep Apnea (OSA)

M. R. Rupp, A. S. Baran, G. D. Marshall; Allergy and Immunology, University of Mississippi Medical Center, Jackson, MS.

Poster Session

2214

Saturday, March 04, 2006

9:45 am to 10:45 am

Allergy Diagnostics and Treatment Extracts

292   Production and Proteomic Characterization of Mite Extracts for Allergy Vaccines

P. MOINGEON ¹, T. BATARD¹, H. CHABRE¹, P. LEMOINE¹, F. T. CHEW²; ¹R&D, Stallergenes SA, Antony, FRANCE, ²Biological Sciences, National University Singapore, Singapore, SINGAPORE.

293   Automated Measurement of Skin Prick Tests

S. Wöhrl ¹, K. Vigl¹, M. Binder², G. Stingl¹, M. Prinz³; ¹Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna, Vienna, AUSTRIA, ²Department of Dermatology, Division of General Dermatology, Medical University of Vienna, Vienna, AUSTRIA, ³Core unit for Medical Statistics and Informatics, Section on Medical Computer Vision, Medical University of Vienna, Vienna, AUSTRIA.

294   The Value of Measuring Total Ige Levels to Judge Atopy in Children with Negative Prick Skin Tests

S. R. Lucas, D. Murphy, H. Carper, L. Heymann, T. A. E. Platts-Mills, P. Heymann; Allergy, Asthma, & Immunology, University of Virginia, Charlottesville, VA.

295   A Novel Approach to the Identification of Allergen Extract Dilutions for Quality Control in the Production Oo Immunotherapy Extract Kits

R. Arora, S. Kosisky, M. Nelson; Department of Allergy/ Immunology, Walter Reed Army Medical Center, Washington, DC.

296   Phenotyping Allergen Sensitization Using Protein Arrays

K. A. Vigh ¹, R. Palanivelu², M. C. Cummings², D. Preuss^2,3; ¹Human Genetics, The University of Chicago, Chicago, IL, ²Molecular Genetics and Cell Biology, The University of Chicago, Chicago, IL, ³Howard Hughes Medical Institute, Chicago, IL.

297   The Relationship between Low Total Serum IgE and Rhinosinusitis

T. Levin ¹, D. Ownby¹, P. Smith¹, J. Ford¹, P. Young¹, E. Peterson², G. Wegienka², M. Maliarik², C. Johnson²; ¹Section of Allergy and Immunology, Medical College of Georgia, Augusta, GA, ²Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI.

298   A Retrospective Review of Patient's Experience and Response to Dog Immunotherapy

T. L. Johnson, II¹, J. P. Forester², C. A. Coop¹, J. P. Dice¹; ¹Allergy/ Immunology, Wilford Hall Medical Center, Lackland AFB, TX, ²Pediatrics, Wilford Hall Medical Center, Lackland AFB, TX.

299   Concomitant Histopathological Findings of Allergic Fungal Sinusitis and Fungal Ball in the Same Sinus: A Rare Case Report

V. Mehta, K. Parks, A. Bewtra; Center for Allergy, Asthma and Immunology, Creighton University Medical Center, Omaha, NE.

Poster Session

2215

Saturday, March 04, 2006

9:45 am to 10:45 am

To Be Announced

300   Individualized Asthma Education in Subsidized Preschools: Improving the Health of a Low-Income Urban Community

J. Purmort, S. Bonner, M. H. Coady, A. Bucciarelli; Center for Urban Epidemiologic Studies, The New York Academy of Medicine, New York, NY.

301   Carboplatin Desensitization

R. MIELGO, M. GARCIMARTÍN, N. FERNANDEZ, A. AMORES, M. QUINTANA, M. GOYACHE, C. MENDIOLA, J. RODRIGUEZ, G. CANTO; ALLERGY, HOSPITAL 12 DE OCTUBRE, MADRID, SPAIN.

302   Systemic Reactions (SR) to Immunotherapy (IT) Using Standardized Extract in Over 700,000 Injections

S. L. Delancy ¹, W. V. Filley², C. E. Aston³, J. R. Claflin²; ¹Nursing, Oklahoma Allergy & Asthma Clinic, Oklahoma City, OK, ²Oklahoma Allergy & Asthma Clinic, Oklahoma City, OK, ³General Clinical Research Center, OUHSC-GCRC, Oklahoma City, OK.

303   Research Bronchoscopy: an Audit of the Volunteers’ Experience

K. K. Jones; Dept of Asthma, Allergy & Respiratory Science, King's College London, London, UNITED KINGDOM.

304   Infantile Eczema as a Predictor of Asthma and Asthma Severity in Preschool Children

K. A. Callahan ¹, E. C. Matsui¹, J. Curtin-Brosnan¹, P. A. Eggleston¹, G. B. Diette²; ¹Pediatric Immunology, Johns Hopkins University, School of Medicine, Baltimore, MD, ²Pulmonary, Johns Hopkins University, School of Medicine, Baltimore, MD.

305   Control of Asthma and Written Asthma Action Plans

R. Chooniedass ^1,2; ¹Pediatric Allergy, University of Manitoba, Winnipeg, MB, CANADA, ²Manitoba Institute of Child Health, Winnipeg, MB, CANADA.

306   Prevalence of Sensitization and Latex Allergy in Operating Room Workers of the Worker's Hospital, Santiago, Chile

C. R. RODAS, Sr.¹, M. A. Guzman, Sr.¹, S. Rojas, Sr.²; ¹IMMUNOLOGY, HOSPITAL CLINICO U CHILE, SANTIAGO, CHILE, ²Medicine, HOSPITAL Trabajador, SANTIAGO, CHILE.

307   Seasonal and Diurnal Variation in the Aeroallergen Concentration in the Atmosphere of Texas Panhandle

N. GHOSH ¹, C. Saadeh², M. Gaylor³, N. Aurora¹; ¹Life Sciences, West Texas A & M UNiversity, Canyon, TX, ²Allergy A.R.T.S., Amarillo Center for Clinical Research 6842 Plum Creek Drive, TX 79124, Amarillo, TX, ³Allergy A.R.T.S., Amarillo Center for Clinical Research 6842 Plum Creek Drive, TX 79124, Amarillo, TX.

308   A Comparative Study of the Relationship of Anxiety Between Allergy and Primary Care Patients

D. González de Olano ¹, L. Moñino Fernández², M. J. Martínez Irazusta³, A. García Morena¹, A. Henriquez Santana¹, G. González Balmaseda⁴; ¹Allergy, Hospital Ramón y Cajal, Madrid, SPAIN, ²Psychiatry, Hospital Gregorio Marañón, Madrid, SPAIN, ³Primary Care Doctor, Centro de Salud Juan de Austria, Madrid, SPAIN, ⁴Psychiatry, Clínica San Miguel, Madrid, SPAIN.

309   The Role of the Pediatric Nurse Practitioner in an Inpatient Asthma Program

A. E. Borgmeyer, P. M. Gyr, L. D. Henry, P. A. Jamerson; St. Louis Children's Hospital, Saint Louis, MO.

310   Mold Damage in New Orleans Homes and Allergic Sensitization in Asthmatic Children

G. E. Eroglu ^1,2, F. Rabito³; ¹Allergy- Immunology, Tulane University, New Orleans, LA, ²Allergy-Immunology and Asthma, Louisiana State University Health Sciences Center, New Orleans, LA, ³School of Public Health, Tulane University, New Orleans, LA.

311   The Prevalence and Diagnostic Value of Toxocariasis in Unknown Eosinophilia

N. Kwon ¹, J. Lee¹, M. Oh¹, S. Lee², D. Choi¹; ¹Division of Allergy, Dept. of Medicine, Samsung Medical Center, Seoul, REPUBLIC OF KOREA, ²Division of Allergy and Pulmonology, Gil Hospital, Gacheon Medical College, Incheon, REPUBLIC OF KOREA.

312   Result of Survey on Asthma in Hanoi Pupils

P. L. Tuan; Hanoi Department of Health, Hanoi, VIET NAM.

313   Clinical and Immunological Peculiarities in Patients with Pollen Allergy and Concomitant Secondary Immunodeficiency

M. Rudenko; Research Institute of Clinical Immunology and Allergology, Rostov State Medical University, Rostov-on-Don, RUSSIAN FEDERATION.

314   Impact of an Education Program on Children Presenting Persistente Bronchial Asthma (PBA)

M. A. Calvo ¹, B. Graff¹, F. Marín²; ¹Pediatrics Institute, Austral University, Valdivia, CHILE, ²Health Public Institute, Austral University, Valdivia, CHILE.

315   The Use of Subcutaneous Immunoglobulin in Imminodeficient Children with Limited IV Access

A. R. Zampelli; Pediatric Rheumatology, Allergy & Immunology, Hershey Medical Center, Hershey, PA.

316   Emotional Bother, Rather than Disease Severity, Determines Environmental Control Practices in Inner-City Preschool Children

J. Curtin-Brosnan, P. A. Eggleston, E. C. Matsui, N. N. Hansel, C. S. Rand, K. A. Callahan, G. B. Diette; Johns Hopkins University, Baltimore, MD.

317   Pharmoeconomics of Penicillin Skin Testing (PST) on Inpatient Antibiotic Use in Patients with Penicillin Allergy (PA)

S. Nootheti, E. Kavosh, L. Bielory; Dept. of Allergy and Immunology, UMDNJ, Newark, NJ.

318   Use of Respiratory Protection in a Mouse Research and Production Facility and Risk of Allergic Sensitization

E. A. O'Neil ¹, K. A. Hagberg¹, B. J. Paigen², P. A. Eggleston³, K. A. Callahan³, E. C. Matsui³; ¹Employee Health Center, The Jackson Laboratory, Bar Harbor, ME, ²Research, The Jackson Laboratory, Bar Harbor, ME, ³School of Medicine, Johns Hopkins University, Baltimore, MD.

319   Smoke Free Laws and Asthma Outcomes

E. J. Hahn, P. Burkhart, M. Rayens, D. Moser, S. Lee; College of Nursing, University of Kentucky, Lexington, KY.

320   Modern Technology Making Immunotherapy Safer

R. G. Houser, J. B. Hunter, S. Shaeffer, L. H. Fisher, T. J. Craig; Allergy/Immunology, Penn State Hershey Medical Center, Hershey, PA.

Oral Abstract Session

2601

Saturday, March 04, 2006

2:00 pm to 3:15 pm

Pharmacotherapy

321   Identification of Novel Chromosomal Regions Associated with Airway Hyperresponsiveness (AHR) in Recombinant Congenic Strains of Mice

P. Camateros ¹, J. Moisan¹, P. D. Lee², R. Marino¹, T. J. Hudson², D. Radzioch¹; ¹Medicine, Division of Experimental Medicine, McGill University, Montreal, PQ, CANADA, ²Montreal Genome Centre, McGill University Health Centre, Montreal, PQ, CANADA.

322   Improved Efficiency of Pulmonary Delivery of Budesonide with Respimat^® Soft Mist™ Inhaler Compared with Turbohaler or pMDI

C. C. Wood ¹, B. van Toor², V. Hasselbarth², H. Stammer², H. Voss²; ¹Respiratory and Immunology Clinical Operations, Boehringer-Ingelheim Pharmaceuticals Inc, Ridgefield, CT, ²Human Pharmacology, Boehringer Ingelheim Pharma KG, Ingelheim, GERMANY.

323   A Study to Evaluate the Handling Performance of Ventolin HFA MDI with Counter in Subjects with Asthma or COPD

R. L. Wasserman ¹, N. W. Locantore², J. Carranza Rosenzweig², C. Crim², W. R. Lincourt²; ¹Pediatric Allergy/Immunology Associates, PA, Dallas, TX, ²GlaxoSmithkline, Research Triangle Park, NC.

324   Single and Multiple Doses of Indacaterol, A Novel Once-Daily b₂-Agonist, Are Well Tolerated in Patients with Mild Asthma

L. Brookman ¹, H. Knight¹, J. Wood¹, S. Perry¹, A. Tarral², B. Elharrar³, S. Pascoe¹; ¹Novartis Horsham Research Centre, Horsham, UNITED KINGDOM, ²Biotrial, Paris, FRANCE, ³Aster-Cephac, Paris, FRANCE.

Oral Abstract Session

2602

Saturday, March 04, 2006

2:00 pm to 3:15 pm

Modulation of the Allergic Immune Response: T Regulatory Cells

325   Rescue of Foxp3 Deficiency by Inducible Activation of a Bicistronic Foxp3/EGFP Allele

W. Lin ¹, N. Truong¹, D. Haribhai², C. B. Williams², T. A. Chatila¹; ¹Department of Pediatrics, UCLA, Los Angeles, CA, ²Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.

326   CD103 is a Marker of Human Suppressor Cells

Z. Allakhverdi ¹, D. Fitzpatrick², M. Comeau², S. Bouguermouh¹, M. Sarfati¹, G. Delespesse¹; ¹Notre-Dame Hospital, CHUM Research Center, Montreal, PQ, CANADA, ²Immunological Systems, Amgen Inc, Seattle, WA.

327   Daily Subcutaneous Injections of Low-Dose Ovalbumin Antigen Induces CD4⁺ CD25⁺ T Regulatory Cells in DO 11 RAG -/- Mice

P. E. Dahlberg ¹, C. M. Seroogy²; ¹Internal Medicine, University of Wisconsin Hospital and Clinics, Madison, WI, ²Pediatrics, University of Wisconsin Hospital and Clinics, Madison, WI.

328   Therapeutic Administration of Allergen-specific CD4⁺CD25⁺ Regulatory T Cells Suppresses Chronic Allergen-induced Airway Inflammation and Remodelling in a Murine Model

J. Kearley, D. S. Robinson, C. M. Lloyd; Leukocyte Biology Section, NHLI, Faculty of Medicine, Imperial College, London, UNITED KINGDOM.

Oral Abstract Session

2603

Saturday, March 04, 2006

2:00 pm to 3:15 pm

The Relationship Between Obesity and Asthma

329   Occurrence of Wheezing and Being Overweight in the First Five Years of Life in a Birth Cohort at High Risk for the Development of Asthma/Allergy

Z. Zhang ¹, H. Lai¹, M. Evans², R. Gangnon², E. Anderson³, J. Gern³, R. Lemanske⁴; ¹Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, ²Biostatistics and medical informatics, University of Wisconsin-Madison, Madison, WI, ³Pediatrics, University of Wisconsin-Madison, Madison, WI, ⁴Pediatrics, Medicine, University of Wisconsin-Madison, Madison, WI.

330   The Relationship of Breastfeeding, Overweight and Asthma in School Children

X. Mai ¹, A. L. Kozyrskyj^1,2, E. A. C. Sellers², J. J. Liem², A. B. Becker²; ¹Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, CANADA, ²Pediatrics & Child Health, University of Manitoba, Winnipeg, MB, CANADA.

331   Elevated BMI at Age 3 Years Predicts Wheeze at Age 5, Independent of Wheeze Earlier in Life

M. S. Perzanowski, I. F. Goldstein, R. G. Barr, B. Sheares, G. L. Chew, R. S. Garfinkel, C. P. Pulgarin, R. M. Whyatt, F. P. Perera, R. L. Miller; Columbia Children's Center for Environmental Health (CCCEH), Columbia University, New York, NY.

332   Body Mass Index (BMI) in Asthmatics is Associated with Airway Neutrophil Response to Inhaled Endotoxin: A Role for Atopic Inflammation

N. E. Alexis ^1,2, M. Almond^1,2, D. B. Peden^1,2; ¹Pediatrics, Center Environmental Med Asthma & Lung Biology, Chapel Hill, NC, ²UNC Chapel Hill, Chapel Hill, NC.

Oral Abstract Session

2604

Saturday, March 04, 2006

2:00 pm to 3:15 pm

Anaphylaxis,Latex

333   Mast Cell Carboxypeptidase as a New Clinical Marker for Anaphylaxis

X. Zhou¹, M. G. Buckley¹, L. C. Lau¹, C. Summers², R. S. H. Pumphrey², A. F. Walls ¹; ¹Immunopharmacology Group, University of Southampton, Southampton, UNITED KINGDOM, ²Department of Immunology, St Mary's Hospital, Manchester, UNITED KINGDOM.

334   Sublingual Epinephrine Tablets Versus EpiPen: Dose Equivalence for Potential First-Aid Treatment of Anaphylaxis

M. M. Rawas-Qalaji¹, F. E. R. Simons², K. J. Simons ¹; ¹Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, CANADA, ²Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, CANADA.

335   Strict Avoidance of Exposure to Natural Rubber Latex (NRL) Glove Products is Associated with Longitudinal Reduction in Percutaneous Reactivity to NAL and Hev B Proteins

H. S. Amin ¹, H. Kalra¹, R. E. Biagini², R. G. Hamilton³, H. Y. Yeang⁴, S. A. M. Arif⁴, D. I. Bernstein¹; ¹Allergy/Immunology, University of Cincinnati Medical Center, Cincinnati, OH, ²CDC/NIOSH, Cincinnati, OH, ³Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Biotechnology and Strategic Research Unit, Rubber Research Institute of Malaysia, Kuala Lumpur, MALAYSIA.

336   Gastrointestinal Allergic Inflammation: IL-9, Mast Cells and Intestinal Anaphylaxis

E. E. Forbes ¹, K. I. Matthaei¹, M. J. Newhouse¹, P. S. Foster^1,2, S. P. Hogan³; ¹Division of Molecular Bioscience, John Curtin School of Medical Research, Canberra, AUSTRALIA, ²Asthma, Allergy and Inflammation Research Centre, University of Newcastle, Newcastle, AUSTRALIA, ³Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

Oral Abstract Session

2605

Saturday, March 04, 2006

2:00 pm to 3:15 pm

Epidemiology

337   Allergic Sensitization to Cat as Major Predictor of Incident Respiratory Allergy in Children

T. Schaefer ¹, G. Woelke², J. Ring³, H. Wichmann⁴, J. Heinrich⁴; ¹Institute of Social Medicine, Medical University, Luebeck, GERMANY, ²GSF - National Research Center for Environment nad Health, Neuherberg, GERMANY, ³Dept. of Dermatology and Allergy, Technical University, Munich, GERMANY, ⁴GSF - National Research Center for Environment and Health, Neuherberg, GERMANY.

338   Maternal Asthma and the Risk of Prematurity

J. J. Liem ¹, A. L. Kozyrskyj², S. F. Mustapha¹, A. B. Becker¹; ¹Section of Allergy and Clinical Immunology, Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, CANADA, ²Faculty of Pharmacy, Community Health Sciences and Pediatrics & Child Health, University of Manitoba, Winnipeg, MB, CANADA.

339   Early Life Exposure to Maternal Stress is Associated with Asthma

A. L. Kozyrskyj ^1,2, P. McGrath³, B. MacNeil⁴, X. Mai^1,5, A. B. Becker², K. T. HayGlass⁵; ¹Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, CANADA, ²Pediatrics & Child Health, University of Manitoba, Winnipeg, MB, CANADA, ³Psychology, Dalhousie University, Halifax, NS, CANADA, ⁴School of Medical Rehabilitation, University of Manitoba, Winnipeg, MB, CANADA, ⁵Immunology, University of Manitoba, Winnipeg, MB, CANADA.

340   Acetaminophen (APAP) Use Predicts Physician Diagnosis Of Asthma: A Multivariate Analysis of the NHANES III Database

G. P. Geba ¹, R. R. Arons²; ¹Mailman School of Public Health, Environmental Health Sciences, Columbia University, New York, NY, ²Mailman School of Public Health, Sociomedical Sciences, Columbia University, New York, NY.

Oral Abstract Session

2606

Saturday, March 04, 2006

2:00 pm to 3:15 pm

Mechanisms of Allergic Inflammation

341   The Major Allergen from Peanut, Ara h 1, is a Ligand of DC-SIGN

W. G. Shreffler ¹, Z. Charlop-Powers¹, R. R. Castro¹, Z. Y. Kucuk¹, A. W. Burks², H. A. Sampson¹; ¹Pediatrics, Division of Allergy & Immunology, Mount Sinai School of Medicine, New York, NY, ²Department of Pediatrics, Division of Allergy/ Immunology, Duke University, Durham, NC.

342   Maintenance and Progression of Human T Helper Type 2 Central Memory T Cells by Thymic Stromal Lymphopoietin Activated Dendritic Cells through OX40-ligand

Y. Wang; Immunology, University of Texas, MD Anderson Cancer Center, Houston, TX.

343   Tgf- b and Volume-Regulated Chloride Channel in the Apoptosis of Human Airway Epithelial Cells

G. Cheng ¹, M. Kim¹, D. Agrawal²; ¹Biomedical Science, Creighton University School of Medicine, Omaha, NE, ²Biomedical Science, Microbiology and Immunology and Allergy, Creighton University School of Medicine, Omaha, NE.

344   A Novel Ige-cd300a Bispecific Antibody Fragment Abolishes Allergic Responses

I. Bachelet, A. Munitz, F. Levi-Schaffer; The School of Pharmacy, Hebrew University of Jerusalem, Jerusalem, ISRAEL.

Oral Abstract Session

2607

Saturday, March 04, 2006

2:00 pm to 3:15 pm

Allergy Diagnostics and Treatment Outcomes

345   Phase 2/3 Study of the Novel Vaccine Amb a 1 Immunostimulatory Oligodeoxyribonucleotide Conjugate AIC in Ragweed-Allergic Adults

W. Busse ¹, G. Gross², P. Korenblat³, N. Nayak⁴, M. Tarpay⁵, D. Levitt⁶; ¹Medicine, University of Wisconsin Medical School, Madison, WI, ²Pharmaceutical Research and Consulting, Inc., Dallas, TX, ³The Clinical Research Center, LLC, St. Louis, MO, ⁴Sneeze, Wheeze and Itch Associates, Normal, IL, ⁵Allergy, Asthma and Clinical Research Center, Oklahoma City, OK, ⁶Dynavax Technologies, Berkeley, CA.

346   Efficacy of Sublingual Immunotherapy (SLIT) with Grass Pollen Allergen in Children and Adolescents

E. Röder ¹, M. Y. Berger², W. C. J. Hop³, R. M. D. Bernsen², H. de Groot¹, R. Gerth van Wijk¹; ¹Dept of Allergology, ErasmusMC, Rotterdam, THE NETHERLANDS, ²Dept of General Practice, ErasmusMC, Rotterdam, THE NETHERLANDS, ³Dept of Epidemiology and Biostatistics, ErasmusMC, Rotterdam, THE NETHERLANDS.

347   Anti-IgE Therapy Inhibits IgE-facilitated Allergen Presentation and Increases the Efficacy of Ragweed Immunotherapy

S. Klunker ¹, J. N. Francis¹, T. B. Casale², S. R. Durham¹; ¹Allergy and Clinical Immunology, Upper Respiratory Medicine, National Heart and Lung Institute, Imperial College, London, UNITED KINGDOM, ²Creighton University School of Medicine, Creighton University, Omaha, NE.

348   Sublingual-Oral Administration of Standardized Allergenic Extracts/Vaccines: Safety and Dosing Studies

R. E. Esch ¹, R. K. Bush^1,2, D. Peden³, R. F. Lockey⁴; ¹Greer Laboratories, Lenoir, NC, ²Allergy & Immunology/ Research, William S Middleton Veterans Memorial Hospital, Madison, WI, ³Pediatrics, University of North Carolina, Chapel Hill, NC, ⁴Allergy & Immunology, University of South Florida, Tampa, FL.

Oral Abstract Session

2608

Saturday, March 04, 2006

2:00 pm to 3:15 pm

Allied Health Oral Abstract Session

349   Asthma Medication Health Beliefs and Controller Medication Use in Inner City Children

A. M. Butz ¹, K. Mudd², C. Lewis¹, M. Donithan³, J. Walker¹, A. Manning¹, M. D. Sellers¹, M. Tsoukleris⁴, M. E. Bollinger⁵; ¹General Pediatrics, Johns Hopkins University, Baltimore, MD, ²Pediatric Allergy and Pulmonology, Univeristy of Maryland, Baltimore, MD, ³Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, ⁴School of Pharmacy, University of Maryland, Baltimore, MD, ⁵Pediatric Allergy and Pulmonology, University of Maryland, Baltimore, MD.

350   Asthma Outcomes Improve with Peak Flow Monitoring

P. V. Burkhart ¹, M. K. Rayens¹, W. R. Revelette²; ¹College of Nursing, University Of Kentucky, Lexington, KY, ²Pediatric and Adolescent Associates, Lexington, KY.

351   Asthma Educational Intervention Effect on Medical Cost and Time Spent Within Rural Households of Children with Asthma

C. J. Lewis ¹, J. Walker¹, L. Lewis-Boyer², K. Hill², L. Pham³, M. Winkelstein², K. Huss⁴, A. Butz¹; ¹School of Medicine, Johns Hopkins University, Baltimore, MD, ²School of Nursing, Johns Hopkins University, Baltimore, MD, ³School of Public Health, Johns Hopkins University, Baltimore, MD, ⁴National Institute of Nursing Research, National Institutes of Health, Bethesdia, MD.

352   Asthma Medication Use in Young Inner-City Asthmatic Children

K. E. Mudd ¹, M. E. Bollinger¹, V. D. Hsu², A. Butz³; ¹Pediatrics, University Of Maryland, Baltimore, MD, ²School of Pharmacy, University Of Maryland, Baltimore, MD, ³Pediatrics, Johns Hopkins University, Baltimore, MD.

Poster Session

3201

Sunday, March 05, 2006 9:45 am to 10:45 am

Pharmacotherapy and Side Effects

353   Progress Toward the Development of Inhibitors of 11beta-Hydroxysteroid dehydrogenase 2: Inhibition of Cortisol Catabolism in the Lung

R. Bateman ¹, D. Rauh², K. Shokat²; ¹U.C. San Francisco, San Francisco, CA, ²Cellular and Molecular Pharmacology, U.C. San Francisco, San Francisco, CA.

354   Relative Amount of Fluticasone Delivered by HFA-MDI to Children of Different Ages

Y. R. Khan; University of Florida, Gainesville, FL.

355   Novel Pressurised Metered Dose Inhaler Aerosol Delivery of Fluticasone Propionate via Tempo^® in Humans

S. B. Shrewsbury ¹, N. M. Mohsen², S. P. Newman³, G. Pitcairn³, T. A. Armer⁴; ¹Clinical & Regulatory Affairs, MAP Pharmaceuticals, Mountain View, CA, ²Senior Scientist, Sheffield Pharmaceuticals, Ann Arbor, MI, ³Pharmaceutical Profiles, Nottingham, UNITED KINGDOM, ⁴Product Development, MAP Pharmaceuticals, Mountain View, CA.

356   Efficacy and Safety of Budesonide Inhalation Suspension in Pediatric Asthma: Japan, Phase III Clinical Trials

A. Akasawa ¹, H. Mikawa², S. Nishima³; ¹National Center for Child Health and Development, Tokyo, JAPAN, ²Kansai Denryoku Hospital School of Nursing for Advanced Practice, Osaka, JAPAN, ³National Hospital Organization Fukuoka National Hospital, Fukuoka, JAPAN.

357   Budesonide prevents Cytokine-induced Decrease of the Relaxant Response to b₂-agonists in Mouse Trachea

M. Adner ¹, L. Cardell¹, A. Miller-Larsson²; ¹ENT, Lab Clin Exp Allergy Research, Malmö University Hospital, Malmö, SWEDEN, ²Medical Science, AstraZeneca R&D Lund, Lund, SWEDEN.

358   Inhaled Corticosteroids and the Risk of Oropharyngeal Adverse Events: Results from a Meta-Analysis

G. S. Rachelefsky ¹, H. Li², N. Liao², Y. Liao², N. J. Combates², R. Faruqi², S. T. Varghese²; ¹Allergy Research Foundation, Inc, Los Angeles, CA, ²Aventis Pharmaceuticals, a member of the sanofi-aventis Group, Bridgewater, NJ.

359   Genome-Scale Analysis of Posttranscriptional Effects of Glucocorticoids (GC)

J. Fan ¹, S. L. Curry¹, U. X. Atasoy², K. G. Becker³, M. Gorospe³, C. Stellato¹; ¹Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, ²University of Missouri-Columbia, Columbia, MO, ³National Institute of Aging, NIH, Baltimore, MD.

360   Control of Airway Inflammation in Asthma Patients Receiving Fluticasone Propionate (FP)/Salmeterol, FP Alone or FP Plus Montelukast

N. Jarjour¹, P. Dorinsky ², J. Stauffer², D. Reilly², S. Yancey², L. Edwards², L. Sutton²; ¹University of Wisconsin School of Medicine, Madison, WI, ²GlaxoSmithKline, Research Triangle Park, NC.

361   Budesonide and Montelukast Once Daily Inhibits Exercise-Induced Bronchoconstriction in 6- to 18-Year-Old Children with Asthma

T. Grzelewski, J. Jerzynska, I. Stelmach; Department of Pediatrics and Allergy, Medical University of Lodz, M Curie Hospital, Zgierz, POLAND.

362   Treatment of Inhaled Corticosteroid and Leukotriene Receptor Antagonistin Korean Young Cough-Variant Asthma Children

J. Jung ¹, J. Lee², J. Kim³; ¹Dong-A University Hospital, Busan, REPUBLIC OF KOREA, ²Masan Samsung Hospital, Masan, REPUBLIC OF KOREA, ³Ulsa University Hospital, Ulsan, REPUBLIC OF KOREA.

363   Early Intervention with High-Dose Inhaled Corticosteroids for Control of Acute Asthma Exacerbations and Improved Outcomes; A Randomized Controlled Trial

E. W. Skorpinski ^1,2, E. Yousef^1,2, S. J. McGeady^1,2; ¹Division of Allergy/Immunology, A.I. duPont Hospital for Children, Wilmington, DE, ²Thomas Jefferson University, Philadelphia, PA.

364   Effect of Once-Daily Evening Administration of Low-Dose Mometasone Furoate on Peak Expiratory Flow in Subjects With Mild-to-Moderate Persistent Asthma

B. Prenner ¹, R. Yao², B. N. Lutsky²; ¹Allergy Associates Medical Group, Inc., San Diego, CA, ²Schering-Plough Research Institute, Kenilworth, NJ.

365   Mometasone Furoate Dry Powder Inhaler Improves Lung Function in Patients With Persistent Asthma and Allergic Rhinitis History

E. J. Schenkel ¹, P. Stryszak², H. Staudinger²; ¹Valley Clinical Research Center, Easton, PA, ²Schering-Plough Research Institute, Kenilworth, NJ.

366   The Effect of Protein Binding on Adrenal Suppression Potential of Inhaled Corticosteroids

H. Derendorf, G. Hochhaus; Department of Pharmaceutics, University of Florida, Gainesville, FL.

367   Ciclesonide Once Daily is Well Tolerated in Children with Mild, Persistent Asthma: a 1-year, Double-blind, Placebo-Controlled Study

J. Maspero ¹, S. Malka², S. Kundu³, M. Lloyd³, D. Banerji³; ¹Sanatorio San José, Fundacion Cidea, Buenos Aires, ARGENTINA, ²Hospital De Clinicas Caracas, Caracas, VENEZUELA, ³Aventis Pharmaceuticals, a member of the sanofi-aventis Group, Bridgewater, NJ.

368   Osteoporosis and its Therapy in Children Treated for Asthma

J. Novak; Paediatric dpt. Hospital, Litomysl, CZECH REPUBLIC.

369   Allergy to Cow Milk Proteins Contaminating Lactose, Common Excipient of Dry Powder Inhalers for Asthma

M. Morisset ¹, D. Moneret-Vautrin¹, N. Commun², A. Schuller¹, G. Kanny¹; ¹Department of Internal Medecine, Clinical Immunology and Allergology, University Hospital, Nancy, FRANCE, ²Hospital Central's Pharmacy, University Hospital, Nancy, FRANCE.

370   Heliox in the Treatment of Patients Hospitalized for Asthma Exacerbations

B. D. Tano ¹, A. L. Bilderback¹, C. S. Rand¹, J. A. Krishnan²; ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Johns Hopkins University School of Medicine and Bloomberg School of Public Health, Baltimore, MD.

371   Steroid Myopathy Masquerading as Restrictive Lung Disease in an Asthmatic Patient

S. E. Owen ¹, C. Glazer², D. Khan¹; ¹Department of Internal Medicine: Division of Allergy and Immunology, University of Texas Southwestern, Dallas, TX, ²Department of Internal Medicine: Division of Pulmonary and Critical Care, University of Texas Southwestern, Dallas, TX.

Poster Session

3202

Sunday, March 05, 2006

9:45 am to 10:45 am

Genetics, Efficacy and Side Effects

372   Effect of Once-Daily Evening Dosing of Low-Dose Mometasone Furoate on Nocturnal Awakenings in Subjects with Mild-to-Moderate Persistent Asthma

F. C. Hampel, Jr. ¹, R. Yao², H. Staudinger²; ¹Central Texas Health Research, New Braunfels, TX, ²Schering-Plough Research Institute, Kenilworth, NJ.

373   Efficacy of Prolonged Budesonide Therapy on Inflammation and Airway Reactivity in a Murine Model of Asthma

S. D. Nandedkar ¹, K. S. Konduri¹, S. Deenamsetty¹, D. A. Rickaby², N. Duzgunes³; ¹Pediatrics, Medical College Of Wisconsin, Milwaukee, WI, ²Physiology, Zablocki VA Medical Center, Milwaukee, WI, ³Microbiology, University of Pacific School of Dentistry, San Franscisco, CA.

374   Lung Growth and Linear Growth in Pre-pubertal Asthmatic Children Under Inhaled Corticosteroid Therapy (ICS)

M. Malucelli, F. Tigrinho, L. Kovalhuk, C. A. Riedi, M. S. Cramer, R. Miyagi, N. Rosario; University of Parana, Curitiba, BRAZIL.

375   The Beclometazone's Impact on Immune and Cytokine Status of Asthma Patients

A. Oliinyk; Allergology, City Allergology Center, Kiev, UKRAINE.

376   Stable Asthma: Unnecessary Over-Exposure to Inhaled Corticosteroid Therapy?

D. K. C. Lee; Department of Respiratory Medicine, Ipswich Hospital, Ipswich, UNITED KINGDOM.

377   Prevention of ICU Admission of Asthmatic Children

G. E. Eroglu; Allergy, Immunology and Asthma, Lousiana Health Scinces Center and Tulane University Medical Center, New Orleans, LA.

378   Value of Determination of Specific IgE Against Recombinant Aspergillus fumigatus Allergens rAsp f1, 2, 3, 4 e 6 in the Diagnosis of Allergic Bronchopulmonary Aspergillosis

E. Oliveira, P. Giavina-Bianchi, J. Kalil; Clinical Immunology and Allergy, FMUSP, São Paulo, BRAZIL.

379   The Chinese Herbal Medicine Formula SA-2121 Inhibits Secretion of Histamine and Interleukin-4 in the Airways of a Murine Model of Allergic Asthma

s. baik, Sr.; harbor ucla medical center, torrance, CA.

380   Effects of High Dose SLIT on Quality of Life in Patients with Seasonal Asthma

C. Incorvaia ¹, G. Riario Sforza¹, C. Pravettoni¹, M. Mauro², P. Puccinelli³, F. Frati³; ¹Allergy/Rheumatology, ICP Hospital, Milan, ITALY, ²Allergy, Sant'Anna Hospital, Como, ITALY, ³Medical Department, Stallergenes Italy, Milan, ITALY.

381   Improvement of the Symptoms and Respiratory Function of Patients with Bronchial Asthma (BA) by Regular Intake of Tomato Juice (TJ)

N. Tamura ¹, N. Nakamura², H. Suganuma², T. Inakuma²; ¹Department of Respiratory Medicine, Koto Hospital, Tokyo, JAPAN, ²Research Institute, Kagome, Tochigi, JAPAN.

382   Thiolated Chitosan Nanoparticles Enhanced Anti-Inflammatory Effects of Intranasally Delivered Theophylline

D. Lee, S. Shirley, X. Kong, R. F. Lockey, S. Mohapatra; Internal Medicine, Univ. of South Florida, Tampa, FL.

383   Association of IL-4 alpha Chain Receptor (IL-4Ra) Polymorphisms and HLA-DR2/DR5 Restriction in Allergic Bronchopulmonary Aspergillosis

A. P. Knutsen, B. Kariuki, P. S. Hutcheson, J. Consolino, R. G. Slavin; Allergy & immunology, Saint Louis University, St. Louis, MO.

384   Mattress Lung: Acrylonitrile-induced Asthma in a Mattress Factory Worker

M. Mohan, S. Kagen, R. Muthiah; Kagen Allergy Clinic, Appleton, WI.

385   Increased Expression in Cd30+ and Cd57+ Molecules on Cd4+ T-cells in Atopic Asthmatic Children: A Preliminary Report

N. E. Martinez-Jimenez, E. Rojas-Ramos; Clinical Immunology and Allergy, ISSSTE, Mexico, D.F., MEXICO.

386   Screening Asthma among Allergic Rhinitis Patients with Peak Expiratory Flow Measurments

M. Herrag; Pulmonary Medecine, Hospital, Rabat, MOROCCO.

387   Prevalance of Pulmonary Nocardiosis in Allergic Bronchopulmonary Disease (Raised Ige Level)

R. S. -.-. ABDUL; -, NATIONAL ALLERGY & ASTHMA CENTRE, KARACHI, PAKISTAN.

388   Timeliness of Diagnosis of Asthma in Children and Associated Factors

W. E. Molis ¹, H. Kita¹, L. A. Lee², R. J. Maki², R. Smith³, T. Chang², A. Weaver⁴, V. Pankratz⁴, R. M. Jacobson², G. A. Poland⁵, Y. J. Juhn²; ¹Division of Allergic Diseases, Mayo Clinic Rochester, Rochester, MN, ²Pediatric and Adolescent Medicine, Mayo Clinic Rochester, Rochester, MN, ³Mayo Medical School, Mayo Clinic Rochester, Rochester, MN, ⁴Department of Health Sciences Research, Mayo Clinic Rochester, Rochester, MN, ⁵Internal Medicine, Mayo Clinic Rochester, Rochester, MN.

389   Risk Factor for Asthma Severity in Children: Family History, Atopic Sensitization or Rhinitis

H. L. B. S. Santos ¹, L. G. Möller¹, N. P. Duarte, Jr.¹, R. Morihisa¹, C. A. Riedi², N. A. Rosario²; ¹Hospital de Clinicas - Universidade Federal do Paraná, Curitiba, BRAZIL, ²Pediatric Immunology and Pneumology, Hospital de Clinicas - Universidade Federal do Paraná, Curitiba, BRAZIL.

Poster Session

3203

Sunday, March 05, 2006

9:45 am to 10:45 am

Adaptive Immunity and Immunoregulation

390   Lung Features of Infection with Corona Virus in Wistar Rats

M. T. Glocker ¹, H. Cabaral¹, J. C. Muiño²; ¹Instituto de Biología Celular, Facultad de Ciencias Médicas - Universidad Nacional de Córdoba, Cordoba, ARGENTINA, ²Medicina III - UHMI N° 4, Facultad de Ciencias Médicas - Universidad Nacional de Córdoba, Cordoba, ARGENTINA.

391   Influence of Il-4 on Prostaglandin and Leukotriene Metabolic Pathways

E. B. Barekzi ¹, J. W. Steinke¹, R. Caughey², L. Borish¹; ¹Asthma and Allergic Diseases Center, University of Virginia, Charlottesville, VA, ²Otolaryngology, University of Virginia, Charlottesville, VA.

392   Transgenic Mice Expressing Catalytically Inactive RAG-1 Exhibit Hypogammaglobulinemia and Altered B Cell Development, but not Autoreactivity

K. W. Parks ¹, A. E. Hassaballa², D. K. Anderson², Q. Hu³, T. B. Casale¹, P. C. Swanson^2,1; ¹Allergy and Immunology, Creighton University, Omaha, NE, ²Medical Microbiology and Immunology, Creighton University, Omaha, NE, ³Pathology, Creighton University, Omaha, NE.

393   Signaling of Human Naïve B Cells Via Toll-like Receptor 7 Induces Immunoglobulin Isotype Switch

S. Narula¹, M. Glaum², D. Song¹, A. Anderson¹, Y. Zheng¹, A. I. Levinson ¹; ¹Medicine, University of Pennsylvania, Philadelphia, PA, ²Medicine, University of South Florida College of Medicine, Tampa, FL.

394   The Absence of HLA B8 and B44 is Associated with Decreased Absolute B Cell Numbers in Common Variable Immunodeficiency

D. T. Johnston, H. W. Schroeder, Jr.; Clinical and Developmental Immunology, University of Alabama at Birmingham, Birmingham, AL.

395   Impaired Maturation of Monocyte Derived Dendritic Cells from Birch Allergic Individuals

R. Casas ¹, K. Duchén¹, O. Zetterström², O. Vaarala¹; ¹Molecular and Clinical Medicine, Paediatrics, Linköping University, SWEDEN, ²Molecular and Clinical Medicine, Allergy Centrum, Linköping University, SWEDEN.

396   Using the Pneumococcal Conjugate Vaccine PCV7 (Prevnar) to Evaluate the Functional Antibody Response in Adults with Recurrent Sinopulmonary Infections

J. Caicedo, S. Skoda-Smith; Pediatrics, University of Florida, Gainesville, FL.

397   Clinical Status, Serum Immunoglobulin G Subclasses and Sputum Il-10 and Mpo Levels in Cf Patients

A. Korzeniewska, J. Jerzynska, I. Stelmach; Department of Pediatrics and Allergy, Medical University of Lodz, M Curie Hospital, Zgierz, POLAND.

398   Evaluation of NK T Cells in Patients with Schistosomiasis and Asthma

R. A. Campos, M. S. Teles, M. J. Martins, O. F. Jesus, B. B. Andrade, A. A. Cruz, M. Araújo, E. M. Carvalho; Internal Medicine, Universidade Federal da Bahia, Salvador-BA, BRAZIL.

399   Successful Treatment Using Interleukin-2 (IL-2) in a Patient with Idiopathic CD4+ Lymphopenia (ICL) and Mycobacterium avium (M.avium)

B. Mandal ¹, V. Bhushan², D. Khan¹; ¹Allergy and Immunology, UT Southwestern, Dallas, TX, ²Hematology/Oncology, UT Southwestern, Dallas, TX.

400   Characterization of the Suppressive Properties of Human CD4+CD25+ T Cells in Atopic and Non-Atopic Individuals

A. M. L. Fonseca, C. Torres, O. M. M. Lourenco, L. M. P. Taborda-Barata; Department of Medical Sciences, Health Sciences Medical Center, University of Beira interior, Covilhã, PORTUGAL.

401   The Effect of Household Endotoxin (ET) Exposure on IgE in Infancy

N. Aichbhaumik ¹, C. C. Johnson¹, S. Havstad¹, D. R. Ownby², L. K. Williams¹, E. M. Zoratti¹; ¹Center for Allergy, Asthma, and Immunology Research, Henry Ford Health System, Detroit, MI, ²Division of Allergy, Medical College of Georgia, Augusta, GA.

402   Interleukin-12 Inhibits Eosinophil Degranulation and Migration but Does not Promote Eosinophil Apoptosis

F. Davoine ¹, C. Ferland², J. Chakir², D. Adamko³, R. Moqbel¹, M. Laviolette²; ¹Dept of Medicine, University of Alberta, Edmonton, AB, CANADA, ²Institut universitaire de cardiologie et de pneumologie de l'Université Laval, Hôpital Laval, Québec, PQ, CANADA, ³Dept of Pediatrics and Medicine, University of Alberta, Edmonton, AB, CANADA.

403   Autoimmune Lymphoproliferative Syndrome Caused by Defects in Mitochondria-Mediated Apoptotic Pathways

J. B. Oliveira ¹, M. J. Lenardo², T. A. Fleisher¹; ¹Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD, ²Laboratory of Immunology, NIAID, National Institutes of Health, Bethesda, MD.

404   Analysis of the Memory CD8+ T Cell Response to RSV Infection

W. W. Stevens ^1,2, J. P. Castillo¹, T. J. Braciale^1,3; ¹Beirne Carter Center for Immunology Research, University of Virginia Health Sciences Center, Charlottesville, VA, ²Microbiology, University of Virginia Health Sciences Center, Charlottesville, VA, ³Pathology, University of Virginia Health Sciences Center, Charlottesville, VA.

405   Asthmatic Children Display Increased Th1 Biased Immunity to Human Metapneumovirus

R. N. Douville ¹, Y. Li², N. Bastien³, A. Becker⁴, A. Kozyrskyj⁵, K. T. HayGlass⁴; ¹Department of Immunology, University of Manitoba/CIHR National Training Program in Allergy and Asthma Research, Winnipeg, MB, CANADA, ²Department of Medical Microbiology, University of Manitoba/Canadian Science Center for Human and Animal, Winnipeg, MB, CANADA, ³Canadian Science Center for Human and Animal Health, Winnipeg, MB, CANADA, ⁴Depts of Immunology/Medical Microbiology/Pediatrics/Child Health, University of Manitoba/CIHR National Training Program in Allergy and Asthma Research, Winnipeg, MB, CANADA, ⁵Depts of Immunology/Pediatrics/Child Health/Community Health Sciences, University of Manitoba/CIHR National Training Program in Allergy and Asthma Research, Winnipeg, MB, CANADA.

406   Recurrent Respiratory Papillomatosis (RRP): Increased T_H2-Like Chemokine Expression

D. W. Rosenthal ^1,2, J. A. Devoti^1,2, R. Wu^3,2, H. Schmidtmayerova⁴, B. M. Steinberg^3,2, V. R. Bonagura^1,2; ¹Allergy/Immunology, Long Island Jewish Medical Center, Great Neck, NY, ²Institute for Medical Research of North Shore-Long Island Jewish Health System, New Hyde Park, NY, ³Otolaryngology, Long Island Jewish Medical Center, New Hyde Park, NY, ⁴Institute for Medical Research of North Shore-Long Island Jewish Health System, Manhasset, NY.

407   Suppression of Toll-like Receptors 3-, 7- and 9-induced B cell Activation and Antibody Production by Repetitive Oligonucleotides from Mammalian Telomere

C. Sackesen ^1,2, M. Akdis¹, J. Zumkehr¹, S. S. Alkan³, K. Blaser¹, I. Gursel⁴, C. A. Akdis¹; ¹Swiss Institute of Allergy and Asthma Research (SIAF), Davos, SWITZERLAND, ²Dept. of Pediatric Allergy and Asthma, Hacettepe University School of Medicine, Ankara, TURKEY, ³3M Pharmaceuticals, St. Paul, MN, ⁴Section of Retroviral Immunology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD.

408   Role of Dendritic Cells in the Induction of Tolerant Versus Effector T Lymphocytes-Mediated Responses to Amoxicillin

R. R-Pena¹, S. Lopez¹, C. Mayorga¹, C. Antunez², M. J. Torres², J. A. Cornejo-Garcia¹, T. D. Fernandez¹, M. Blanca ²; ¹Research Lab, Carlos Haya Hospital, Malaga, SPAIN, ²Allergy Service, Carlos Haya Hospital, Malaga, SPAIN.

409   CTLA-4 + and CD25+ T Cells Down Regulation are Associated to Severe Respiratory Syncytial Virus Infection

P. V. Díaz ¹, R. A. Pinto², A. A. Gaggero³, S. M. Arredondo⁴, M. Bono⁵; ¹Pathophysiology Program, ICBM, Faculty of Medicine, University of Chile, Santiago, CHILE, ²Pediatric Department, Faculty of Medicine, University of Chile, Santiago, CHILE, ³Virology Program , ICBM, Faculty of Medicine, University of Chile, Santiago, CHILE, ⁴Immunology, National Institute of Chest Disease, Santiago, CHILE, ⁵Immunology, Faculty of Science, University of Chile, Santiago, CHILE.

Poster Session

3204

Sunday, March 05, 2006 9:45 am to 10:45 am

Primary Immunodeficiency 1

410   Loss of Memory B Cells May be an Early Marker for Common Variable Immune Deficiency

C. T. Cady ^1,2, R. J. Harbeck¹, C. H. Kirkpatrick²; ¹Medicine, NJMRC, Denver, CO, ²University of Colorado Health Sciences Center, Denver, CO.

411   Population Prevalence of Diagnosed Primary Immune Deficiency Diseases in the United States

J. M. Boyle ¹, R. H. Buckley²; ¹Immune Deficiency Foundation, Towson, MD, ²Duke University School of Medicine, Durham, NC.

412   In Vitro Induction of IgA Expression in Ataxia Telangiectasia (A-T) Patients with IgA Deficiency (IgAD)

T. V. Le, H. M. Lederman; Pediatrics, Johns Hopkins Medical Institute, Baltimore, MD.

413   Rituximab Treatment to Control Epstein-Barr Virus (EBV) Infection in X-Linked Lymphoproliferative Disorder (XLP)

B. J. Mark ¹, A. P. Knutsen²; ¹Department of Internal Medicine, Division of Allergy and Immunology, Saint Louis University School of Medicine, St. Louis, MO, ²Department of Pediatrics, Division of Allergy and Immunology, Saint Louis University School of Medicine, St. Louis, MO.

414   Decreased Lymphocyte Mitogen Responses at Diagnosis Are Associated with Increased Morbidity in Common Variable Immunodeficiency Patients

C. M. Davis, C. A. Kozinetz, L. M. Noroski; Pediatrics, Baylor College of Medicine, Houston, TX.

415   Hypergammaglobulinemia, IgG₂ Subclass Deficiency and Recurrent Infections in Adults

C. B. Lauter; Division of Allergy & Clinical Immunology, William Beaumont Hospital, Royal Oak, MI.

416   Peripheral Naive B-Cell Phenotype in X-Linked Severe Combined Immunodeficiency (XSCID) Patients with Hypogammaglobulinemia After Bone Marrow Transplantation

J. Chinen ¹, D. Moratto¹, M. R. Kirby¹, G. F. Linton², H. L. Malech², J. M. Puck¹; ¹Genetics and Molecular Biology Branch, NHGRI-NIH, Bethesda, MD, ²Laboratory of Host Defenses, NIAID-NIH, Bethesda, MD.

417   Chronic Rhinosinusitis (crs) in Primary Immunodeficient Patients

A. B. F. Fomin ¹, E. B. Farah¹, M. S. Nascimento¹, A. B. M. Castro¹, A. C. Pastorino¹, E. M. G. Carnide¹, C. M. A. Jacob¹, L. A. N. Oliveira²; ¹Unidade de Alergia e imunologia, Hospital das Clínicas - Instituto da Criança, São paulo, BRAZIL, ²Unidade de Radiologia, Hospital das Clínicas - Instituto da Criança, São paulo, BRAZIL.

418   Lung Involvement During Follow-Up of 12 patients with Agammaglobulinemia

E. G. Marins ¹, M. B. Dorna², E. M. G. Carnide², A. C. Pastorino², A. B. F. Fomin², A. P. B. M. Castro², C. M. A. Jacob²; ¹Departamento de Imunologia e Alergia, Instituto da Criança do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, BRAZIL, ²Allergy and Immunology, Instituto da Criança do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, BRAZIL.

419   Results of the us Pivotal Trial Of Self-Administered Subcutaneous Immunoglobulin Replacement Therapy in Primary Immune Deficiency Diseases

H. D. Ochs ^1,2; ¹Immunology, University of Washington, Seattle, WA, ²Childrens Hospital and Regional Medical Center, Seattle, WA.

420   Parathyroid Gland Transplantation without Posttransplantation Immunosuppression

I. K. Chinn, B. H. Devlin, M. A. Alexieff, J. Li, E. McCarthy, M. A. Skinner, J. A. Olson, Jr., M. L. Markert; Pediatrics, Duke University Medical Center, Durham, NC.

421   Percentage of Patients Experiencing Local Infusion-site Reactions During Subcutaneous Immunoglobulin Therapy Decreases Rapidly Upon Repeated Infusions

M. R. Stein ¹, H. D. Ochs², C. Investigators³; ¹Allergy Associates of the Palm Beaches, North Palm Beach, FL, ²Pediatrics, University of Washington School of Medicine, Seattle, WA, ³ZLB Behring, Marburg, GERMANY.

422   Clinical and Immunologic Manifestations of Transplacentally Acquired Maternal T-Cells in SCID

K. Palmer ¹, T. D. Green¹, J. L. Roberts¹, E. Sajaroff¹, M. Cooney¹, K. Coyne¹, D. Chen², N. L. Reinsmoen², R. H. Buckley¹; ¹Pediatric Allergy and Immunology, Duke University Medical Center, Durham, NC, ²Department of Pathology, Duke University Medical Center, Durham, NC.

423   The Effect of Desloratadine (D) and Montelukast (M) both on Antigen Specific Immune Response and Lymphoid Apoptosis in Rats

I. Kaidashev ¹, N. Kutzenko¹, I. Yastremskaya¹, L. M. DuBuske²; ¹Ukrainian Medical Stomatological Academy, Poltava, UKRAINE, ²Immunology Research Institute of New England, Gardner, MA.

424   Conversion from Intravenous to Subcutaneous Immunolgobulin Therapy: Relationship Between Dose, Serum Trough IgG Concentration and Infection Rate in Patients with Primary Immune Deficiency Diseases

M. Berger ¹, H. Ochs², &. CE1200 Investigators³; ¹Pediatrics, Case Western Reserve University, Cleveland, OH, ²Pediatrics, University of Washington School of Medicine, Seattle, WA, ³ZLB Behring, King of Prussia, PA.

425   The Clinical Syndrome of Specific Antibody Deficiency (SAD) in Children

R. J. Boyle ¹, C. Le², A. Balloch¹, M. L. Tang¹; ¹Infection and Environment Division, Murdoch Children's Research Institute, Parkville, AUSTRALIA, ²Intensive Care, Royal Children's Hospital, Parkville, AUSTRALIA.

426   Evaluation of Immunological Features in IgM Deficiency

S. Ramanuja, S. Gupta, L. Yel; Department of Medicine, University of California at Irvine, Irvine, CA.

427   Immune Defects in Rubinstein-Taybi Syndrome With and Without Deletion of CREBBP

D. R. Naimi ¹, J. Munoz², J. Rubinstein³, R. W. Hostoffer, Jr.⁴; ¹Division of Allergy and Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA, ²Pediatric Infectious Diseases, Maria Fareri Children's Hospital, Valhalla, NY, ³Pediatrics, Cincinnatti Children's Hospital, Cincinnatti, OH, ⁴Pediatrics, Case Western Reserve University, Cleveland, OH.

428   Monoclonal Gammopathy in Patients with B Cell Immunodeficiency

R. Herzog, A. Rubinstein; Allergy and Immunology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY.

429   Antibody Deficiency in the New Millennium: Illnesses, Absences, and Concomitant Medications- 100 Patient Years Experience

E. A. Cassidy ¹, P. J. Pinciaro², M. Berger¹, *. for the Grifols 04, 04-OLE, IG201 Investigators³; ¹Rainbow Babies and Children's Hospital, Cleveland, OH, ²Probitas Pharma, Inc., Millersville, MD, ³Instituto Grifols, Barcelona, SPAIN.

430   A Case of a Child with Lymphangiectasia and Lymphedema Associated with Hypogammaglobulinemia and Lymphopenia

A. L. Cox, P. Ponda, V. R. Bonagura; Allergy & Immunology, North Shore-Long Island Jewish Health System, New Hyde Park, NY.

431   Common Variable Immunodeficiency Presenting as Lymphonodular Hyperplasia, Pernicious Anemia and Breast Cancer

M. W. Reder, L. Wild; Allergy and Clinical Immunology, Tulane University Medical Center, New Orleans, LA.

432   Beta Blockers, Ace Inhibitors, and Angiotensin Receptor Blockers in Hymenoptera Allergy: A 5 Year Chart Review

R. T. Misiak; Internal Medicine, University of Michigan, Ann Arbor, MI.

Poster Session

3205

Sunday, March 05, 2006 9:45 am to 10:45 am

Aerobiology, allergens, infections and immune reponses

433   Indoor Spore Levels in Asthmatic and Control Homes

F. Hu, L. D. Johnson, K. Kennedy, J. M. Portnoy, C. S. Barnes; Allergy/Asthma/Immunology, Children's Mercy Hospital, Kansas City, MO.

434   Date Palm Pollen: A Significant Asthma and Allergy Inducer

R. A. Radwan¹, M. M. Barakat², M. A. Selim³, E. E. Fouda ⁴; ¹Biochemistry Department, Faculty of Pharmacy, Cairo University, Cairo, EGYPT, ²Biochemistry, Faculty of Pharmacy, Cairo University, Cairo, EGYPT, ³Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo, EGYPT, ⁴Allergy and Immunology Center, Al-Azhar University, Cairo, EGYPT.

435   Comparison of Pollen Allergy versus Mold Allergy in Asthmatic and Allergic Rhinitis Patients

C. E. Lowe, III, P. J. Dowling, M. C. Amado, C. S. Barnes; Allergy/Asthma/Immunology, Children's Mercy Hospital, Kansas City, MO.

436   Fungal Presence in Typical Midwest Homes

C. S. Barnes, K. Wagoner, F. HU, L. D. Johnson, K. Kennedy, J. M. Portnoy; Allergy/Asthma/Immunology, Children's Mercy Hospital, Kansas City, MO.

437   Typical Outdoor Levels of Airborne Non-Viable Fungal Spores Collected at the Ground Level During the Spring and Early Summer in Florida

R. Codina, J. J. Mele, L. S. Cohen, Jr.; Environmental, SDII Global Corporation, Tampa, FL.

438   Description of Platanus (London Plane Tree) Pollen Levels and Pollen Sensitization in an Australian Population

P. K. Burton ^1,2; ¹Immunology, Westmead Hospital, Westmead, AUSTRALIA, ²Department of Clinical Immunlogy/Allergy, Immunology/Allergy, Sydney, AUSTRALIA.

439   Epidemiology and Aerobiology of Ambrosia Artemisiifolia between 1988 to 2004

F. Della Torre ¹, A. Limonta², A. Molinari³, P. Benaglio³, S. Vercelloni³, E. Della Torre²; ¹Pneumologic Department (Chief dr.E.Marchi), INRCA, Casatenovo (LC), ITALY, ²Pneumologic Department, INRCA, Casatenovo (LC), ITALY, ³Pubblic Health Laboratory, ASL LECCO, Oggiono (LC), ITALY.

440   Changes in Immune Responses to Cat Allergens during Prolonged Avoidance: Is Tolerance Reversible

E. A. Erwin, A. J. Reefer, L. Naccara, D. Bunyan, J. A. Woodfolk, T. A. E. Platts-Mills; University VA, Charlottesville, VA.

441   Allergen-Specific T-Cell Reactivity at Physiologically Relevant Allergen Concentrations

K. Lund, A. Millner, T. Lenhard, H. Ipsen, P. A. Würtzen; Experimental Immunology, ALK-Abello, Hørsholm, DENMARK.

442   Immunological Evaluation of Patients with Mold Related Symptoms

D. A. Edmondson ¹, C. S. Barrios¹, T. L. Brasel², D. C. Straus², V. P. Kurup¹, J. N. Fink¹; ¹Allergy and Immunology, Medical College of Wisconsin, Milwaukee, WI, ²Microbiology and Immunology, Texas Tech University, Lubbock, TX.

443   Effects of Allergen Challenge on a Chronic Animal Model of Alternaria Sensitivity

J. E. Knuffman ^1,2, H. Sanchez², M. A. Opsahl³, R. L. Sorkness¹, R. K. Bush²; ¹Allergy, University of Wisconsin, Madison, WI, ²Allergy, William S. Middleton VA Hospital, Madison, WI, ³Allergy, Wiliam S. Middleton VA Hospital, Madison, WI.

444   Trichophyton Allergy: Role in Asthma, Rhinitis and Urticaria/Angioedema

R. D. R. Oliveira¹, M. Thiesen¹, F. R. Oliveira¹, A. S. Zampolo¹, M. C. Rodrigues¹, L. R. Roberti², L. Arruda ¹; ¹Medicine, School of Medicine of Ribeirão Preto-University of São Paulo, Ribeirão Preto, BRAZIL, ²Pediatrics, School of Medicine of Ribeirão Preto-University of São Paulo, Ribeirão Preto, BRAZIL.

445   Oral Pathogens and Asthma: A Potential Connection

S. J. Arbes, Jr., E. A. Cohen, M. L. Sever, D. C. Zeldin; NIEHS/NIH, Research Triangle Park, NC.

446   Toll-like Receptor 3 (TLR3) Ligand Exacerbates Pre-existing Allergic Airway Inflammation in Murine Asthma Model

H. Nagase ¹, N. Yamashita², T. Adachi¹, J. Nakano¹, K. Ohta¹; ¹Department of Internal Medicine, Teikyo University, Tokyo, JAPAN, ²Department of Pharmacy, Musashino University, Nishi-Tokyo, JAPAN.

447   Infection with Rhinovirus Induces a Systemic IP-10 Response

S. Kakumanu, M. Evans, W. W. Busse, J. E. Gern; Allergy/ Immunology, UW Madison, Madison, WI.

448   Expression of Matrix Metalloproteinase-12 in Persistent Alveolar Macrophage Clusters in Rats with a Chronic Asthma-Like Phenotype

L. A. Rosenthal ¹, R. J. Szakaly¹, R. F. Lemanske, Jr.¹, R. L. Sorkness^1,2; ¹University of Wisconsin Medical School, Madison, WI, ²School of Pharmacy, University of Wisconsin-Madison, Madison, WI.

449   Immunological Characterization of a Hypoallergenic Folding Variant of rBet v 1

H. Fiebig, H. Kahlert, R. Suck, B. Weber, O. Cromwell; Allergopharma Joachim Ganzer KG, Reinbek, GERMANY.

Poster Session

3206

Sunday, March 05, 2006 9:45 am to 10:45 am

Allergens: Molecular Biology, Structure and Function and Cross-Reactivity

450   Identification and Characterization of Per a 2, the Bla g 2 Allergen Homologue from American Cockroach (Periplaneta americana)

Q. R. Pan, S. M. Wang, H. S. Shang, F. T. Chew; Biological Sciences, National University of Singapore, Singapore, SINGAPORE.

451   What is House Dust Mite Allergy in a Community with no House Dust Mites?

S. T. Sigurdardottir ^1,2, B. Adalsteinsdottir^1,2, T. Gislason^1,2, B. Kristensen³, D. Gislason¹; ¹Landspitali University Hospital, Reykjavik, ICELAND, ²University of Iceland, Reykjavik, ICELAND, ³Pharmacia Diagnostic, Copenhagen, DENMARK.

452   [Withdrawn]

453   Purification and Characterization of Blattella germanica Serine Protease

S. Wünschmann ¹, S. M. Satinover², J. A. Woodfolk², M. D. Chapman¹, A. Pomés¹; ¹INDOOR Biotechnologies Inc., Charlottesville, VA, ²Allergy Division, University of Virginia, Charlottesville, VA.

454   Differential IgE Binding to Recombinant Tropomyosin Orthologs from Different Dust Mite Species Localizes Critical Epitope Regions

H. L. Nah, A. S. L. Tay, A. H. B. Loo, F. T. Chew; Department of Biological Sciences, National University of Singapore, Singapore, SINGAPORE.

455   Epitope Mapping of Der f 13, a Group 13 Allergen from Dust Mite Dermatophagoides farinae and Generation of Triple Mutant 3A as a Potential Hypoallergen

S. L. Chan, F. T. Chew, Y. K. Mok; Department of Biological Sciences, National University of Singapore, Singapore, SINGAPORE.

456   Allergic Reactions to Common Allergens may be Due to Evolutionary Immune Response to Conserved Domains (CDs) Present in Parasites and Allergens

B. P. Bielory¹, T. John², L. Bielory ³; ¹University of Michigan, Ann Arbor, MI, ²UMDNJ - New Jersey Medical School, Newark, NJ, ³Medicine, Pediatrics & Ophthalmology, UMDNJ - New Jersey Medical School, Newark, NJ.

457   Use of Cross-reacting Carbohydrate Determinants (CCD) in Specific IgE Detection

U. Banik; Product Support Allergy & Infectious Disease, Diagnostic Products Corporation, Los Angeles, CA.

458   Bla g 6: A Calcium Binding German Cockroach Allergen Involved in Muscle Contraction

J. Hindley ¹, S. Wünschmann¹, L. D. Vailes¹, S. M. Satinover², J. A. Woodfolk², M. D. Chapman¹, A. Pomés¹; ¹R&D, INDOOR Biotechnologies, Inc., Charlottesville, VA, ²Allergy Division, University of Virginia, Charlottesville, VA.

459   Screening for Conformational Epitopes Using Heat Denaturation of Allergens on ELISA Plates

B. Ning, R. M. Goldblum, D. M. Estes, M. A. Endsley, M. Watanabe, T. Midoro-Horiuti; Pediatrics, University TX Medical Branch, Galveston, TX.

460   Biochemical Characterization of Intact Allergen Extracts and Chemically Modified Allergoids Representing Grass, Birch and House Dust Mite Allergen Extracts

H. Henmar, K. Meno, L. Friberg, G. N. Hansen, A. Giselsson, H. Ipsen; Research Department, ALK-Abelló A/S, Hørsholm, DENMARK.

461   Cloning and Characterization of Art v 2 from Artemisia Vulgaris Pollen

J. Asturias1, C. Arilla1, I. Ibarrola1, J. Daza2, Y. Puente3, A. Martinez ¹; 1R & D, Bial-Arístegui, Bilbao, SPAIN, 2Alergia, Hospital Virgen Macarena, Sevilla, SPAIN, 3Alergoclínica Virgen de Loreto, Córdoba, SPAIN.

462   Potential Alternative ELISA Assays to Detect Alt A1 Using IgM and IgG Antibodies

M. Abebe, V. Kumar, S. Sevinc, H. M. Vijay; Environmental Health, Health Canada, Ottawa, ON, CANADA.

463   Epitope Mapping of Der p 2 by Site-directed Mutagenesis: Differential IgE Binding Epitope Profiles among Individuals Sensitized to Only Dermatophagoides spp. and those with Non-pyroglyphid Mite Responses

K. Reginald, F. T. Chew; Department of Biological Science, National University of Singapore, Singapore, SINGAPORE.

464   Sensitization to Thyreophagus Entomophagus and other Mite Species in Cuban Patients with Allergic Asthma and/or Rhinoconjunctivitis

F. de la Torre Morín ¹, R. Aguila de la Coba², M. Gallego³, V. Iraola³, E. Fernández-Caldas³; ¹Hospital Virgen de la Candelaria, Tenerife, SPAIN, ²Hospital Pediatrico el Cerro, La Habana, CUBA, ³Laboratorios LETI, S.L., Tres Cantos, SPAIN.

465   Analysis of N-Glycosylation in Vespula Vulgaris Hyaluronidase Ves v 2

U. R. Seppälä ¹, K. Mutenda², R. Monsalve³, L. Skov⁴, T. P. King⁵, H. Ipsen¹, P. Roepstorff², M. D. Spangfort⁶; ¹Vaccine Research, ALK-Abello´, Horsholm, DENMARK, ²Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, DENMARK, ³Biochemical Research, ALK-Abello´, Madrid, SPAIN, ⁴Biostructural Research, Department of Medicinal Chemistry,, The Danish University of Pharmaceutical Sciences, Copenhagen, DENMARK, ⁵Rockefeller University, New York, NY, ⁶Research Department, ALK-Abello´, Horsholm, DENMARK.

466   Co-sensitization Not Due to Cross-reactivity Between Paralogs of Group 5 Allergens from Blomia tropicalis and Dermatophagoides Farinae

Y. Gao ¹, D. Y. Wang², F. T. Chew¹; ¹Biological Sciences, National University of Singapore, Singapore, SINGAPORE, ²Otolaryngology, National University of Singapore, Singapore, SINGAPORE.

467   Purification and Characterization of Pen b 26 Allergen of Penicillium brevicompactum Expressed in Escherichia coli

S. Sevinc, V. Kumar, M. Abebe, H. Vijay; Inhalation Toxicology and Aerobiology, Health Canada, Ottawa, ON, CANADA.

468   Genomic Organization and Characterization of Group 2 Allergen Paralogs from Dermatophagoides Farinae

C. L. Tan, K. Reginald, F. T. Chew; Biological Sciences, National University of Singapore, Singapore, SINGAPORE.

469   Cross Comparison between the IgE Binding Profiles of Cyclophilins from Human, Mouse, Dust Mites and Fungi

S. S. Joshi, H. Y. Gan, F. T. Chew; Biological Science, National University of Singapore, Singapore, SINGAPORE.

Poster Session

3207

Sunday, March 05, 2006

9:45 am to 10:45 am

Urticaria and Angioedema

470   Use of the LAD-2 Mast Cell Line to Assess Mast Cell Degranulation Induced by Sera From Chronic Idiopathic Urticaria Patients

A. M. Ditto, R. P. Schleimer, C. Sheen, M. Kulka; Allergy-Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL.

471   Levocetirizine: H₁-Receptor Occupancy in Allergic Children Age 6-11 Years

K. J. Simons ¹, F. E. R. Simons², M. Strolin-Benedetti³, M. Gillard³, E. Baltes³; ¹Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, CANADA, ²Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, CANADA, ³Pharma Sector, UCB S.A., Braine-l'Alleud, BELGIUM.

472   Study of the Role of Basophils in Skin Biopsies of Urticaria

M. M. Ferrer ¹, M. A. Idoate², P. Gil³; ¹Allergy and Clinical Immunology, Clinica Universitaria Navarra, Pamplona, SPAIN, ²Pathology, Clinica Universitaria Navarra, Pamplona, SPAIN, ³Dermatology, Clinica Universitaria Navarra, Pamplona, SPAIN.

473   Severity of Autoimmune Urticaria is not Different than in Children with Chronic Urticaria from Other Causes

P. Sangacharoenkit, S. Pongpreuksa, S. Boonchoo, P. Vichyanond, N. Visitsunthorn, O. Jirapongsananuruk; Allergy and Immunology division, Pediatric department, Siriraj Hospital, Mahidol University, Bangkok, THAILAND.

474   The Utility of Skin Biopsy in the Diagnosis and Management of Chronic Urticaria: Correlation with Response to Antihistamine Therapy

M. Punar ¹, S. Patel², A. Carlson¹, M. Pasha³; ¹Pathology and Laboratory Medicine, Albany Medical College, Albany, NY, ²Medicine, Albany Medical College, Albany, NY, ³Allergy and Immunology, Albany Medical College, Albany, NY.

475   Clinical Evaluation of Tolerance and Viral Safety of Human C1-inhibitor Concentrate in Patients with Recurrent Angioedema Due to Hereditary (HAE) or Acquired (AAE) C1 Inhibitor Deficiency

M. Bulnes; Allergy, Hospital La Paz, Spain, SPAIN.

476   Comparison of Autologous Serum Test (AST) Between Healthy Volunteers and Patients with Chronic Idiopathic Urticaria (CIU).PK Vedanthan* PA Mahesh^, AD Holla^, AK Prabhakar^. *Univ. of Colorado Health Sciences Center, Denver, Colorado USA; ^ Allergy, Asthma and Chest Center, Mysore, INDIA

P. K. Vedanthan; Medicine, Univ. of Colorado Health Sciences Center, Lakewood, CO.

477   Serum Concentration of Dehydroepiandrosterone Sulphate (DHEA-S) in Female Patients with Chronic Idiopathic Urticaria (CIU)

A. Kasperska-Zajac, Z. Brzoza, B. Rogala; Chair and Clinical Department of Internal Diseases, Allergology and Clinical Immunology, Medical University of Silesia, Zabrze, POLAND.

478   Sulfasalazine is Beneficial in the Treatment of Recalcitrant Chronic Idiopathic Urticaria

L. Y. McGirt, L. A. Beck; Medicine - Clinical Immunology, Johns Hopkins School of Medicine, Baltimore, MD.

479   Hereditary Angioedema Due to C1 Inhibitor Deficiency: New Findings Concerning Symptoms and Affected Organs

K. Bork, P. Staubach, G. Meng; Department of Dermatology, University of Mainz, Mainz, GERMANY.

480   Successful Treatment of Refractory Chronic Idiopathic Urticaria with Mycophenolate Mofetil

S. L. Ridz, D. A. Khan; Division of Allergy and Immunology, UT Southwestern Medical Center, Dallas, TX.

481   Autoantibodies Against the High Affinity IgE Receptor (FceR1a) are Equally Prevalent in Patients with Auto-Immune Thyroid Disease, Chronic Idiopathic Urticaria and Controls

J. Mozena, J. W. Steinke, L. Borish; University Of Virginia Health Systems, Charlottesville, VA.

482   Basophil Histamine Release (HR) Activity and Disease Severity in Chronic Idiopathic Urticaria (CIU)

R. Baker¹, N. Ohameje¹, K. Vasagar¹, L. Gober¹, S. Chen², B. M. Vonakis¹, S. S. Saini ¹; ¹Johns Hopkins Allergy Asthma Center, Baltimore, MD, ²Emory University, Atlanta, GA.

483   C Reactive Protein (CRP) & IgG Anti-IgE/IgE Receptor (FCeR1) Antibodies in Chronic Idiopathic Urticaria (CIU)

M. Kaviani, R. J. Warrington; Adult Allergy & Clinical Immunology, University of Manitoba, Winnipeg, MB, CANADA.

484   Temperature-dependent, Aquagenic Urticaria/anaphylaxis (tdaa)

K. Shamir ¹, G. Browne², V. Beltrani³, L. Bielory⁴; ¹Allergy and Immunology, UMDNJ-New Jersey Medical School, Newark, NJ, ²Internal Medicine, UMDNJ-Robert Wood Johnson University Hospital, New Brunswick, NJ, ³Dermatology, Columbia University College of Physicians & Surgeons, New York, NY, ⁴Allergy, Immunology, & Rheumatology, UMDNJ-New Jersey Medical School, Newark, NJ.

485   Hereditary Angioedema: Safety of Long-Term Androgen Therapy

C. Lee; Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA.

486   Pharmacokinetics of Pasteurized C1-Inhibitor Concentrate (Berinert P) in 40 Patients with Hereditary Angioedema

I. Martinez-Saguer, E. Rusicke, E. Aygören-Pürsün, W. Kreuz; Centre of Pediatrics III, Department of Hematology, Hemostaseology and Oncology, Comprehensive Care, J.-W. Goethe University Hospital Frankfurt, Germany, Frankfurt, GERMANY.

487   Ten Year Retrospective Study of the Contributing Factors to Angioedema in the Inpatient Allergy/Immunology Consult Service

A. Banerji, P. Hesterberg, Y. Hsu, H. J. Chen, J. T. Wong; Department of Rheumatology, Allergy & Immunology, MGH, Boston, MA.

488   Indolent Systemic Mastocitosis with Germline D816V Somatic c-kit Mutation Evolving to an Acute Myeloid Leukemia

L. Escribano ¹, R. Núñez-López¹, M. Jara², A. García-Montero², A. Prados¹, C. Teodosio², A. Iglesias¹, M. Sanchez², A. Orfao²; ¹Mast Cell Unit, Hospital Ramón y Cajal, Madrid, SPAIN, ²Servicio de Citometría, Centro de Investigación del Cáncer y Departamento de Medicina, Universidad de Salamanca, Salamanca, SPAIN.

489   Longitudinal Disease Progression in Mastocytosis Syndromes: a Retrospective Chart Review

N. M. Vogel ¹, A. E. Lichtin², F. H. Hsieh¹; ¹Pulmonary, Allergy and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, OH, ²Hematology and Medical Oncology, Cleveland Clinic Foundation, Cleveland, OH.

490   Acquired Angioedema Type I (AAE-I) Associated to Non-Hodgkin Lymphoma

P. Vasquez, M. A. Sgrazzutti, P. Domenichini, A. E. Romanelli, R. D. Rebagliati, G. D. Ramón, S. Garbiero; Allergy and Immunology, Hospital Italiano Regional del Sur, Bahía Blanca, ARGENTINA.

491   Mastocytosis in the Child

A. C. Zenea-Capote ¹, J. Moneda²; ¹Pediatric, Health Center Montesa, Madrid, SPAIN, ²Dermatology, “William Soler” Pediatric Hospital, La Habana, CUBA.

492   Mastocytosis in the Child

A. C. Zenea-Capote ¹, J. Moneda², A. Piñero-Fernandez³, R. Rodriguez-Gavalda¹; ¹Allergology, “William Soler” Pediatric Hospital, La Habana, CUBA, ²Dermatology, “William Soler” Pediatric Hospital, La Habana, CUBA, ³Library, Institute of Hematology and Immunology, La Habana, CUBA.

493   Urticarial vasculitis and Thyroid autoimmunity: A study of 21 patients

I. M. CHERREZ-OJEDA ¹, T. Cazar², T. Guerrero¹, R. Mantilla¹, E. Uraga³, A. Tafur¹; ¹ALLERGY, KENNEDY HOSPITAL, GUAYAQUIL, ECUADOR, ²Dermatology, Luis Vernaza Hospital, GUAYAQUIL, ECUADOR, ³Dermatology, LUIS VERNAZA HOSPITAL, GUAYAQUIL, ECUADOR.

494   A Case Report of Cold-Induced Urticaria with Atypical Results to Ice-Cube Testing

A. S. Kim, B. Yu, J. Moy; Allergy & Immunology, Rush University Medical Center & Stroger Hospital of Cook County, chicago, IL.

495   Desensitization to Clopidogrel and Ticlopidine in Two Patients with Coronary Artery Disease and Indwelling Drug-Eluting Stents

N. J. Nam, D. Chau, R. L. Miller, S. M. Canfield; Medicine, Columbia University College of Phys. & Surg., New York, NY.

496   Etiology of Chronic Urticaria in Latinoamerican people

I. M. CHERREZ-OJEDA ¹, T. CAZAR², E. URAGA², R. MANTILLA¹, T. GUERRERO¹, J. MORENO¹; ¹ALLERGY, KENNEDY HOSPITAL, GUAYAQUIL, ECUADOR, ²Dermatology, LUIS VERNAZA HOSPITAL, GUAYAQUIL, ECUADOR.

497   Clinical Improvement in a Pediatric Male with Hereditary Angioedema Treated with Oxandrolone

S. Baxi ¹, P. C. Giclas², N. Johnson³, R. P. Nelson, Jr.⁴; ¹Pediatrics, Section of Allergy/Immunology, Children's Mercy Hospital, Kansas City, MO, ²National Jewish Medical and Research Center, Denver, CO, ³Pediatrics, Division of Pediatric Endocrinology, Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, IN, ⁴Medicine, Division of Hematology/Oncology, Indiana University School of Medicine, Indianapolis, IN.

498   Severe Angioedema and Hypocomplementemic Vasculitis in a Patient with Systemic Lupus Erythematosus (SLE): Rapid Response to IV Cyclophosphamide

J. C. Martin, L. D. Truong, N. M. Janssen; Baylor College of Medicine, Houston, TX.

499   The Cerebral Processing of Itch - An Investigation with Functional Magnetic Resonance Tomography

U. Darsow ¹, M. Valet², F. Pfab¹, H. Behrendt¹, T. R. Toelle², J. Ring¹; ¹Dept. of Dermatology and Allergy Biederstein/Center for Allergy and Environment, TU Munich, Muenchen, GERMANY, ²Dept. of Neurology, TU Munich, Muenchen, GERMANY.

Poster Session

3208

Sunday, March 05, 2006 9:45 am to 10:45 am

Anaphylaxis, Insects, and Latex

500   Epidemiology of Mosquito Bite Allergy in the Centre of Allergy and Clinical Immunology of Monterrey, Mexico

A. Arias-Cruz, E. Avitia-Valenzuela, S. N. González-Díaz, G. Galindo-Rodríguez; Allergy and Clinical Immunology, University Hospital, Monterrey, N.L., MEXICO.

501   Circulating Specific IgE to Gliadin Can be a Useful Marker for Diagnosing Wheat-Dependent Exercise-Induced Anaphylaxis Patients Among the Wheat-Sensitized Patients

J. Lee ¹, S. Yoon², Y. Ye², S. Kim², H. Park²; ¹Department of internal medicine, College of medicine, Hallym University, Chunchon, REPUBLIC OF KOREA, ²Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA.

502   Anaphylaxis in Children in Central Israel

B. Garty, V. Hoffer, N. Marcus, O. Schoerman, Y. Levy, Y. Finkelstein, Y. L. Danon; Schneider Children Medical Center of Israel, Petah Tikva, ISRAEL.

503   Purification of Insect Venom Proteins

D. R. Hoffman; Pathology and Laboratory Medicine, Brody School of Medicine, Greenville, NC.

504   Comparison of Quality of Life in Dermal Reactors Referred to an Out-Patient Clinic Versus Patients Recruited by Advertisement

H. N. G. Oude Elberink ¹, G. H. Guyatt², A. E. J. Dubois¹; ¹Allergology, University Medical Center Groningen, Groningen, THE NETHERLANDS, ²Epidemiology, McMaster University, Hamilton, ON, CANADA.

505   Anaphylaxis to Pachycondyla Chinensis

T. M. Leath ¹, T. J. Grier², R. S. Jacobson², M. E. Fontana-Penn¹; ¹Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC, ²Research & Development Laboratory, Greer Laboratories Inc., Lenoir, NC.

506   Bullous Pemphigoid in a Newborn with Evidence of Maternal Transmission

A. S. Hartel, J. W. Sleasman, N. Tangsinmankong; Allergy and Immunology, University of South Florida, Saint Petersburg, FL.

507   Allergic Contact Dermatitis to Diallyl Disulphide in Spain

J. L. Garcia-Abujeta ¹, M. Ferrer², P. Gaig³, C. Martinez-Cocera⁴, A. Gonzalo-Garijo⁵, M. Garces⁶, F. Rodriguez⁷, P. Iriarte⁸, T. Soto⁹, D. Muñoz¹⁰, I. Sanchez¹¹, T. Lobera¹²; ¹Consulta de Alergología, Centro Especialidades, Benidorm, SPAIN, ²Servicio de Alergología, Clinica Universitaria de Navarra, Pamplona, SPAIN, ³Servicio de Alergología, Hospital Universitario Juan XXIII, Tarragona, SPAIN, ⁴Servicio de Alergología, Hospital San Carlos, Madrid, SPAIN, ⁵Servicio de Alergología, Hospital Infanta Cristina, Badajoz, SPAIN, ⁶Servicio de Alergología, Hospital Clinico, Zaragoza, SPAIN, ⁷Sección de Alergología, Hospital Marques de Valdecilla, Santander, SPAIN, ⁸Sección de Alergología, Hospital Arquitecto Marcide, El Ferrol, SPAIN, ⁹Servicio de Alergología, Hospital Clinico, Pontevedra, SPAIN, ¹⁰Servicio de Alergología e Inmunologia, Hospital Santiago Apostol, Vitoria-Gasteiz, SPAIN, ¹¹Servicio de Alergología, Hospital Virgen de la Candelaria, Tenerife, SPAIN, ¹²Serviciio de Alergología, Hospital San Millan-San Pedro, Logroño, SPAIN.

508   Adverse Reactions to Orthodontic Appliances in Nickel-Allergic Patients

K. K. Volkman, M. C. Zacharisen; Medical College of Wisconsin, Milwaukee, WI.

509   Frequency of Contact Allergy to Fragrances (CAF) in an Unselected Patch Test Population

T. Oppel, E. Scharrer, B. Przybilla; Klinik und Poliklinik für Dermatologie und Allergologie, Ludwig-Maximilians University, Munich, GERMANY.

510   New Important Allergens in Cosmetics

H. D. Oei ¹, S. B. Tjiook¹, W. L. Kartanegara¹, R. L. Oei²; ¹Department of Allergology, Albert Schweitzer Hospital, Dordrecht, THE NETHERLANDS, ²Faculty of Medicine, University of Maastricht, Maastricht, THE NETHERLANDS.

511   A Modified Latex Hevein (Hev b 6.02) Retains Lymphozyte Proliferation Response

C. Hafner ¹, S. Wagner², J. Jasinska³, D. Allwardt^2,1, O. Scheiner², U. Wiedermann³, H. Breiteneder²; ¹Department of Dermatology, Medical University of Vienna, Vienna, AUSTRIA, ²Department of Pathophysiology, Medical University of Vienna, Vienna, AUSTRIA, ³Department of Specific Prophylaxis and Tropical Medicine, Medical University of Vienna, Vienna, AUSTRIA.

512   Safety of Sublingual Latex Immunotherapy. Are Specific IgE to Recombinant Latex Allergens a Risk Factor?

A. Spínola Santos ¹, M. Branco Ferreira¹, A. Lopes Pregal¹, S. Lopes da Silva¹, A. Mendes¹, E. Pedro¹, F. Nunes², M. L. Palma-Carlos³, M. C. Santos⁴, A. G. Palma-Carlos³, M. Pereira Barbosa¹; ¹Immunoalergology Unit, Hospital Santa Maria, Lisbon, PORTUGAL, ²PharmaciaDiagnostics, Lisbon, PORTUGAL, ³CHIUL, Faculdade de Medicina de Lisboa, Lisbon, PORTUGAL, ⁴Unidade de Imunologia Clínica, Instituto de Medicina Molecular-FML, Lisbon, PORTUGAL.

513   Immune Responses Induced by Latex Allergens after Gastrointestinal Challenge in Mice

C. S. Barrios ¹, V. P. Kurup^1,2, J. D. Henderson, Jr.³, J. N. Fink¹, K. J. Kelly¹; ¹Pediatrics, Medical College Of Wisconsin, Milwaukee, WI, ²Research Service, VA Medical Center, Milwaukee, WI, ³Surgery, Medical College Of Wisconsin, Milwaukee, WI.

514   Comparison of Microarray-Based IgE Profiling with Established Diagnostic Methods in Patients with Latex Allergy

C. M. Schroeder ¹, H. Ott¹, S. Stanzel², V. Mahler³, M. Raulf-Heimsoth⁴, H. F. Merk¹, J. M. Baron¹; ¹Dept. of Dermatology, RWTH Aachen, Aachen, GERMANY, ²Institue of Medical Statistics, RWTH Aachen, Aachen, GERMANY, ³Dept. of Dermatology, Universitiy of Erlangen, Erlangen, GERMANY, ⁴Professionals Associations´ Research Institute for Occupational Medicine, University Bochum, Bochum, GERMANY.

515   The Role of Glycosylation of nHev b 2, The ß-1,3-Glucanase from Hevea Brasiliensis Latex, in IgE Recognition

U. Seifert ¹, S. Wagner¹, M. Bublin¹, C. Ebner², C. Hafner³, A. Mari⁴, S. Arija M Arif⁵, H. Y. Yeang⁵, O. Scheiner¹, H. Breiteneder¹; ¹Department of Pathophysiology, Medical University of Vienna, Vienna, AUSTRIA, ²Allergieambulatorium Reumannplatz, Vienna, AUSTRIA, ³Department of Dermatology, Medical University of Vienna, Vienna, AUSTRIA, ⁴National Health Service, Rome, ITALY, ⁵Rubber Research Institute of Malaysia, Sungai Buloh, MALAYSIA.

516   Allergen Concentration in Natural Rubber Latex

H. Y. Yeang ¹, R. G. Hamilton², D. I. Bernstein³, S. A. M. Arif¹, K. S. Chow¹, Y. H. Loke¹, M. Raulf-Heimsoth⁴, S. Wagner⁵, H. Breiteneder⁵, R. E. Biagini⁶; ¹Biotechnology and Strategic Research Unit, Rubber Research Institute of Malaysia, Sungei Buloh, MALAYSIA, ²Johns Hopkins Asthma and Allergy Center, Johns Hopkins University School of Medicine, Baltimore, MD, ³Division of Allergy/Immunology, University of Cincinnati College of Medicine, Cincinnati, OH, ⁴Allergy/Immunology Division, Institute of Occupational Medicine, Bochum, GERMANY, ⁵Department of Pathophysiology, Medical University of Vienna, Vienna, AUSTRIA, ⁶Biomonitoring and Health Assessment Branch, National Institute of Occupational Safety and Health, Cincinnati, OH.

517   The Association between Alcohol Consumption and Atopy in Danish Adults

A. Linneberg, I. Hertzum; Research Centre for Prevention and Health, Copenhagen, DENMARK.

518   Transfer of Experimental Asthma by CD4 T-Cells from Mice with Food-Induced Intestinal Immediate Type Hypersensitivity

C. Ozdemir ¹, S. Sel², I. Schöll³, A. O. Yildirim⁴, N. Blümer², H. Fehrenbach⁴, I. B. Barlan¹, H. Renz², S. Sel²; ¹Marmara University Division of Pediatric Allergy and Immunology, Istanbul, TURKEY, ²Department of Clinical Chemistry and Molecular Diagnostics, Hospital of the Philipps-University Marburg, Marburg, GERMANY, ³Institute of Pathophysiology, Medical University of Vienna, Vienna, AUSTRIA, ⁴Department of Internal Medicine (Respiratory Medicine), Philipps-University of Marburg, Marburg, GERMANY.

519   Urticaria after Local Anesthetic Skin Testing with a History of Local Anesthetic Anaphylactic Reaction

G. M. Sanders; Univ. MI Medical Center, Ann Arbor, MI.

520   A Case of Prolonged Anaphylaxis Caused by Persistent Exposure to Food Antigen

L. S. Greos; Colorado Allergy and Asthma Centers, P.C., Englewood, CO.

521   Occupational Contact Anaphylaxis from Piperacillin in a Nurse with Atopic Dermatitis

J. Bahn, Sr., J. Lee, Sr., K. Eom, Sr., S. Jang, Sr., K. Jung, Sr.; Pulmonary, Allergy, and Critical Care Medicine, Hallym University Sacred Heart Hospital, Anyang, REPUBLIC OF KOREA.

522   A Child Case of Anaphylaxis to Polyvinylpyrrolidone Containing Medicines

T. Itazawa, Y. Adachi, Y. Okabe, Y. S. Adachi, M. Nakabayashi, T. Harai, K. Miya, K. Uese, T. Miyawaki; Dept of Pediatrics, Toyama University, Toyama, JAPAN.

523   Immunotherapy Shot Reaction Manifesting with Delayed-Onset of Severe, Rapidly Progressive Anaphylaxis: Case Report and Post-Event Analysis

S. N. Marks ¹, D. H. Summers¹, R. J. M. Engler²; ¹Allergy-Immunology, Landstuhl Regional Medical Center, Landstuhl, GERMANY, ²Allergy-Immunology, Walter Reed Army Medical Center, Washington, DC.

524   Management of Food-Induced Anaphylaxis by Caregivers and Medical Professionals: A Survey

E. Simons ¹, C. Weiss², A. Muñoz-Furlong², T. J. Furlong², S. H. Sicherer¹; ¹Division of Allergy and Immunology, Mount Sinai School of Medicine, New York, NY, ²Food Allergy & Anaphylaxis Network, Fairfax, VA.

525   Essential Role of Sphingosine Kinase in IgE-mediated Allergic Response in vivo and ex vivo

P. N. Pushparaj, A. J. Melendez; Department of Physiology, National University of Singapore, Singapore, SINGAPORE.

526   Specific siRNA Targeting of Sphingosine Kinase 1 in vivo Ameliorates IgE-Mediated Anaphylaxis

P. N. Pushparaj, A. J. Melendez; Department of Physiology, National University of Singapore, Singapore, SINGAPORE.

Poster Session

3209

Sunday, March 05, 2006

9:45 am to 10:45 am

Epidemiology and Health care Delivery

527   Asthma Control in Spain. Do Seasonal Period and Treatment Pattern Matter? ESCASE Study

A. Fueyo ¹, M. Ruiz², J. Ancochea², M. Guilera³, X. Badia³; ¹GlaxoSmithKline, Madrid, SPAIN, ²Hospital La Princesa, Madrid, SPAIN, ³HOR-Europe, Barcelona, SPAIN.

528   Cost-effectiveness Analysis of Using Allergy Tests in Primary Care in Italian Children

U. Ytterström-Ahlstedt†¹, N. Zethraeus², C. J. Petersson¹, S. Ahlstedt ^1,3; ¹Pharmacia Diagnostics AB, Uppsala, SWEDEN, ²Central for Health Economics, Stockholm School of Economics, Stockholm, SWEDEN, ³Dep of Environmental Medicine and Center of Allergy Research, Karolinska Institute, Stockholm, SWEDEN.

529   Trends for Inpatient A&I Consultations for Asthma at a Tertiary Referral Center

K. S. Tsai, I. Hussain; Allergy and Immunology, Washington University in St. Louis School of Medicine, St. Louis, MO.

530   Clinic Care Patterns of Patients with Suspected Immunodefects

A. Shah ¹, P. Sidi², J. Doucette³, L. Estrella⁴, C. Cunningham-Rundles⁴; ¹Department of Internal Medicine, Mt. Sinai Hospital, New York, NY, ²Information Technology, Mt. Sinai Hospital, New York, NY, ³Department of Community & Preventive Medicine, Mt. Sinai Hospital, New York, NY, ⁴Departments of Medicine and Pediatrics, Mt. Sinai Hospital, New York, NY.

531   National Survey of Hospitalization Rate of Asthma in Taiwan, 1996-2003

K. Yeh, L. Ou, J. Huang; Department of Pediatrics, Chang Gung Children's Hospital, Taoyuan, TAIWAN REPUBLIC OF CHINA.

532   Allergic Diseases : Insight and Reallity inThailand

N. Siriwaradon, T. Thongkaew, P. Chatchatee, J. Ngamphaiboon; Division of Allergy and Clinical Immunology, Department of Pediatrics, Chulalongkorn University Hospital, Bangkok, THAILAND.

533   Cost-Effectiveness of Sublingual Specific Immuno-Therapy Versus Current Symptomatic Treatments in Adults with Allergic Rhinitis and Asthma, in the Societal Perspective

P. Berto ^1,2, G. W. Canonica³, N. Crimi⁴, F. Frati^5,6, C. Ortolani⁷, G. Passalacqua³, G. Senna⁸; ¹pbe consulting, Verona, ITALY, ²Facoltà di Farmacia, Università di Padova, Padova, ITALY, ³Clinica di Malattie dell'Apparato Respiratorio e Allergologia Dipartimento di Medicina Interna, Università di Genova, Genova, ITALY, ⁴Cattedra di Malattie dell'Apparato Respiratorio, Università degli Studi di Catania, Catania, ITALY, ⁵Stallergenes Italia Srl, Scientific Department, Milano, ITALY, ⁶Clinica Pediatrica, Università di Perugia, Perugia, ITALY, ⁷Istituto Sacra Famiglia, Istituto Allergologico Lombardo OnLus, Cesano Boscone (Milano), ITALY, ⁸Unità Operativa di Allergologia, Azienda Ospedaliera di Verona - Ospedale Civile Maggiore, Verona, ITALY.

534   Reversal of Italian Reimbursement Restriction on Antihistamines is Associated with Better Clinical Outcomes among Children with Allergy-Induced Asthma

D. S. Battleman ¹, C. Burudtakdee¹, J. Tierce¹, M. Sturkenboom^2,3, C. Giaquinto^2,4, G. Picelli^2,3, L. Cantarutti², P. Berto⁵, G. Canonica⁶; ¹ValueMedics Research, LLC, Falls Church, VA, ²Pedianet, Padova, ITALY, ³International Pharmacoepidemiology and Pharmacoeconomics Research Center, Desio (MI), ITALY, ⁴Department of Paediatrics, University of Padova, Padova, ITALY, ⁵PBE Consulting, Verona, ITALY, ⁶Department of Internal Medicine, University of Genoa, Genoa, ITALY.

535   Medicare Reimbursement of IGIV Negatively Impacts Patients’ Access to Care

J. B. Scharpf ¹, J. M. Boyle², M. B. Vogel¹; ¹Immune Deficiency Foundation, Towson, MD, ²Schulman, Ronca and Bucuvalas, Inc., Rockville, MD.

536   Children with RSV Infection Who Sought Medical Care Had High Prevalence of Family History of Atopy

E. K. Miller, T. V. Hartert, K. A. Poehling, M. R. Griffin, K. E. Edwards; Vanderbilt University Medical Center, Nashville, TN.

537   The Trend of Atopic Disease in Transylvania, Romania

D. M. Dumitrascu, D. Arion, S. Tatar; 3rd Medical Clinic, Allergy Dept, University of Medicine @ Pharmacy, Cluj-Napoca, ROMANIA.

538   School Survey Shows Asthma and Eczema are Still Increasing in Tokyo

M. Futamura ^1,2, Y. Ohya^1,2, M. Akashi^1,2, N. Kojima^1,2, K. Akiyama², K. Takahashi², T. Nakagawa², F. Kobayashi², A. Eboshida², H. Nakamura², H. Odajima², Y. Adachi², A. Akasawa^1,2; ¹National Center for Child Health and Development, Tokyo, JAPAN, ²Japanese Asthma Survey Group, Tokyo, JAPAN.

539   Epidemiology of Medication “Allergy” at a Tertiary Care Center

D. M. Lang, N. M. Vogel, A. Jain; Allergy/Immunology, Cleveland Clinic Foundation, Cleveland, OH.

540   Environmental Exposures In Rural Homes: Parent Report vs. Allergen Dust Samples

L. L. Lewis-Boyer, Sr. ¹, K. L. Hill¹, J. M. Walker¹, C. J. Lewis¹, M. Winkelstein¹, L. Pham², A. Butz²; ¹School of Nursing, Johns Hopkins University, Baltimore, MD, ²School of Medicine, Johns Hopkins University, Baltimore, MD.

541   Regional Differences in EpiPen Prescriptions in the United States

C. A. Camargo, Jr. ¹, S. Clark¹, M. S. Kaplan², P. Lieberman³, R. A. Wood⁴; ¹Emergency Medicine, Massachusetts General Hospital, Boston, MA, ²Kaiser Permanente, Los Angeles, CA, ³Allergy & Asthma Care, Cordova, TN, ⁴Johns Hopkins Medical Center, Baltimore, MD.

Poster Session

3210

Sunday, March 05, 2006 9:45 am to 10:45 am

Quality of Life

542   Effect on Quality of Life Of Multidisciplinary Psycho-educational Group Interventions - A Randomized Controlled Trial

L. Fernandes ¹, J. A. Fonseca^2,3, A. Costa-pereira², L. Delgado⁴, S. Martins³, A. Moreira³, A. Feteira³, V. Abreu³, M. Vaz³, M. Castel-Branco³; ¹Psiquiatria, Faculdade Medicina Universidade do Porto, Porto, PORTUGAL, ²Bioestatística e Informática Médica, Faculdade Medicina Universidade do Porto, Porto, PORTUGAL, ³Serviço de Imunoalergologia do HSJ, Porto, PORTUGAL, ⁴Imunologia, Faculdade Medicina Universidade do Porto, Porto, PORTUGAL.

543   The Impact of Asthma on Child and Parental Quality of Life in Lithuania

E. Vaitkaitiene; Social Pediatrics, Biomedical Research Institute of Kaunas University of Medicine, Kaunas, LITHUANIA.

544   Quality of Life of Children with Allergic Diseases

Y. Adachi ¹, Y. Okabe¹, T. Itazawa¹, Y. S. Adachi¹, M. Nakabayashi¹, T. Fuchizawa¹, T. Miyawaki¹, H. Odajima²; ¹Dept of Pediatrics, Toyama Medical & Pharmaceutical University, Toyama, JAPAN, ²Dept of Pediatrics, Fukuoka National Hospital, Fukuoka, JAPAN.

545   Impaired Quality of Life in Child Asthmatics in Tokyo, Japan

N. Kojima ^1,2, Y. Ohya^1,2, M. Futamura^1,2, M. Akashi^1,2, K. Akiyama², K. Takahashi², T. Nakagawa², F. Kobayashi², A. Eboshida², H. Nakamura², H. Odajima², Y. Adachi², A. Akasawa^1,2; ¹National Center for Child Health and Development, Tokyo, JAPAN, ²Japanese Asthma Survey Group, Tokyo, JAPAN.

Poster Session

3211

Sunday, March 05, 2006 9:45 am to 10:45 am

Mechanisms of Allergic Inflammation

546   Masking of Corticosteroid-induced Inhibition of NF-kB activation by (S)-Albuterol in Human Airway Smooth Muscle Cells and Human Blood Lymphocytes

D. K. Agrawal ¹, G. Cheng¹, P. W. Kelbe²; ¹Biomedical Sciences, Creighton University School of Medicine, Omaha, NE, ²Medical Liason, Sepracor Inc., Marlborough, MA.

547   Expression of Cysteinyl Leukotriene Receptors by CD34+ Umbilical Cord Blood (CB) - Progenitor Cells: Relevance to Atopic Development

J. A. ROA, A. J. BAATJES, L. D. SALEH, M. M. CYR, G. M. GAUVREAU, J. A. DENBURG; Division of clinical immunology and allergy, department of medicine, FACULTY OF HEALTH SCIENCES, McMASTER UNIVERSITY, HAMILTON, ON, CANADA.

548   Genetic Variability in Pulmonary Physiological Responses to Cockroach and Dust Mite Allergen in A/J and C56BL/6 Mice

S. B. Sarpong ¹, E. Asamoa-Odei², V. Kamendi³, J. Okomo-Awich⁴; ¹Howard University, Washington, DC, ²College Of Medicine, Howard University, Washington, WA, ³Nursing, Howard University, Washington, DC, ⁴Microbiology, Howard University, Washington, DC.

549   LTC4S(A-444C) Polymorphism is Associated with Severity of Exercise-Induced Asthma in Children

M. Kang ¹, H. Kim¹, S. Lee², J. Kim¹, B. Kim¹, S. Jang¹, J. Shim³, S. Hong¹; ¹Pediatrics, Asan Medical Center, Seoul, REPUBLIC OF KOREA, ²Pediatrics, Hallym Medical Center, Seoul, REPUBLIC OF KOREA, ³Pediatrics, SungKyunKwan University, Seoul, REPUBLIC OF KOREA.

550   A Polymorphism in the HLA-G 3’-UTR Influences Targeting of mir-148 and is Associated with Asthma

Z. Tan ¹, J. Fan², A. M. Shon¹, M. G. Schwartz¹, B. Camoretti-Mercado³, C. Ober¹; ¹Department of Human Genetics, University of Chicago, Chicago, IL, ²Skirball Institute, New York University School of Medicine, New York, NY, ³Department of Medicine, University of Chicago, Chicago, IL.

551   Prostaglandin E2 Induces Exocytosis and Eicosanoid Generation by Human Mast Cells through an Il-4-Dependent Mechanism

C. Feng, J. A. Boyce; Medicine, Brigham and Women's Hospital, Boston, MA.

552   Trefoil Factor 2 (TFF2) is Induced by Allergen and IL-13 in Lung Goblet Cells and Modulates Airway Inflammatory Cell Number

N. M. Nikolaidis ¹, P. C. Fulkerson², T. C. Wang³, M. E. Rothenberg⁴; ¹Cell and Molecular Biology, University of Cincinnati, Cincinnati, OH, ²Molecular Genetics, University Of Cincinnati, Cincinnati, OH, ³Division of Digestive and Liver Diseases, Columbia University, New York, NY, ⁴Division of Allergy and Immunology, Cincinnati Childrens Hospital Medical Center, Cincinnati, OH.

553   Signaling by the CysLT2 Receptor: Involvement of PKA, PKC and Downstream AP-1 and NF-kB Elements in IL-8 Gene Transcription

C. Thompson ¹, A. Cloutier², Y. Bossé¹, P. Larivée², P. McDonald², J. Stankova¹, M. Rola-Pleszczynski¹; ¹Immunology division, Université de Sherbrooke, Sherbrooke, PQ, CANADA, ²Pulmonary division, Université de Sherbrooke, Sherbrooke, PQ, CANADA.

554   The Mechanism of Self-Perpetuated Activation of ERK1/2 in Airway Cells in the Absence of Allergen Exposure in a Mouse Model of Chronic Asthma

R. Alam, Q. Liang, N. Goplen, W. Liu, S. Rozario, R. Vepachedu, L. Guo, M. M. Gorska; Medicine, National Jewish Medical and Research Center, Denver, CO.

555   Direct Stimulation of Guinea Pig Nasal Sensory Nerves by Leukotriene D4 and Histamine

T. E. Taylor-Clark, M. Lee, B. J. Undem; Allergy & Clinical Immunology, Johns Hopkins Medicine, Baltimore, MD.

556   Crystal Structure of Human Carbonyl Reductase 1 Implications for Structure Based Drug Design

D. Rauh; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA.

557   Stat6 Nuclear Export Elements are Unique from other Stat Family Members

M. B. Ericksen, M. O. Daines, G. K. Khurana Hershey; CCHMC, Cincinnati, OH.

558   Involvement of Adhesion Signaling in GM-CSF-induced Activation of Eosinophils; Evidence of Shp2- Slp76-mediated Cross-talk Between the bc Receptor and ICAM-1

K. Pazdrak ¹, T. W. Young¹, J. Wiktorowicz¹, A. R. Brasier², A. Kurosky¹; ¹Human Biological Chemistry and Genetics, University of Texas Medical Branch, Galveston, TX, ²Internal Medicine, University of Texas Medical Branch, Galveston, TX.

559   Potential Role of the Glucocorticoid Receptor (GCR) Beta in Glucocorticoid (GC) Dependent Histone H4 Acetylation

L. B. Li, D. Y. M. Leung, E. Goleva; National Jewish Medical and Research Center, Denver, CO.

560   Lipoxin A₄ (LXA₄) and Leukotriene C₄ (LTC₄) Levels in Nasal Lavages after Intranasal Provocation with Aspirin in Aspirin Sensitive and Aspirin Tolerant Patients

M. Kupczyk, I. Kuprys´-Lipin´ska, M. Bochen´ska-Marciniak, A. Antczak, P. Górski, P. Kuna; Department of Pneumonology and Allergy, Medical University of Lodz, Lodz, POLAND.

561   Bronchoalveolar Lavage Leukotriene C₄/D₄/E₄ Levels in Acute Asthma and Acute Bronchiolitis

C. K. Kim ¹, J. Y. Koh¹, M. Hoekendijk¹, Y. Y. Koh²; ¹Pediatric Asthma/Allergy Center, Inje University, Sanggyepaik Hospital, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, Seoul National University Hospital, Seoul, REPUBLIC OF KOREA.

562   Unc119, a Novel Src Kinase Activator, Enhances Myofibroblast Transformation of Human Lung Fibroblasts

R. S. Vepachedu, N. A. Singhania, M. M. Gorska, R. Alam; Medicine, National Jewish Medical and Research Center, Denver, CO.

563   PI-3 Kinase Upregulation: a Constituent of Pollen NADPH Oxidase-induced Signal 1?

C. C. Horner ¹, N. Dharajiya¹, I. Boldogh², S. Sur¹; ¹Allergy, Pulmonary, Immunology, Critical Care & Sleep, University of Texas Medical Branch, Galveston, TX, ²Microbiology & Immunology, University of Texas Medical Branch, Galveston, TX.

564   Resolution of Airway Eosinophilia is Associated with Upregulation of Fas Ligand (FasL) Expression After a Single Aspergillus fumigatus (Af) Challenge of Sensitized Mice

S. K. Sharma ¹, S. Kierstein², A. Pitt³, F. Almeida³, J. Peterson¹, X. Yang², J. Zangrilli^1,3, A. Haczku²; ¹Center for Translational Medicine, Thomas Jefferson University, Philadelphia, PA, ²Pulmonary, Allergy and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia, PA, ³Division of Critical Care, Pulmonary, Allergic and Immunologic Diseases, Thomas Jefferson University, Philadelphia, PA.

565   Dexamethasone Modulates CysLT1R Expression in Human Monocytes

J. Stankova; Immunology division, Pediatrics, Université de Sherbrooke, Sherbrooke, PQ, CANADA.

566   Allergen-Induced Airway Hyperresponsiveness Mediated by Cyclooxygenase Inhibition is not Dependent on 5-Lipoxygenase or IL-5, but is IL-13 Dependent

R. Peebles, Jr. ¹, K. Hashimoto², J. R. Sheller¹, M. L. Moore¹, J. D. Morrow¹, S. Ji³, J. A. Elias⁴, K. Goleniewska¹, J. F. O'Neal¹, D. B. Mitchell¹, B. S. Graham⁵, W. Zhou¹; ¹Vanderbilt Univ School Of Medicine, Nashville, TN, ²Microbiology, Fukushima Medical University, Fukushima, JAPAN, ³LINCO Research, St. Charles, MO, ⁴Yale Univ School Of Medicine, New Haven, CT, ⁵NIAID, Bethesda, MD.

567   Involvement of PKCj in the Development of Airway Hyperreactivity and Inflammation in a Mouse Model of Asthma

K. S. Park ¹, J. Do², S. Nam²; ¹Pediatrics, Presbyterian Medical Center, Jeonju, REPUBLIC OF KOREA, ²Biological Science, Jeonju University, Jeonju, REPUBLIC OF KOREA.

568   Synergy for Glucocorticoid Receptor [GR] Translocation by Dexamethasone and Albuterol: Effects of Receptor Antagonists

N. Bulayeva ¹, J. L. Rabbitt¹, S. Friday², W. J. Calhoun¹; ¹Allergy, Pulmonary, Immunology, CCM, and Sleep, University of Texas Medical Branch, Galveston, TX, ²PACCM, University of Pittsburgh, Pittsburgh, PA.

569   Calcium-Calmodulin Mediates House Dust Mite-Induced ERK Activation and Interleukin-8 Production in Human Respiratory Epithelial Cells

E. Kim ¹, K. Lee¹, C. Kim², Y. Shin³, M. Sohn¹, K. Kim¹; ¹Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA, ²Pediatrics, Kwandong University, Seoul, REPUBLIC OF KOREA, ³Pediatrics, Pochon CHA University College of Medicine, Seoul, REPUBLIC OF KOREA.

570   Induction of Interleukin-13 Receptor Expression Via Nuclear Factor-Kappab Activation in Human Tonsillar B Cells

O. Hajoui, H. Zheng, J. Guay, B. Mazer; Meakins Christie Lab, McGill University, Montréal, PQ, CANADA.

571   Immunomodulation by Dietary n3-Polyunsaturated Fatty Acids (PUFA) In Vitro

C. Koch ¹, L. Brovkina^1,2, R. Ruehl³, M. Worm¹; ¹Dpt. of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, GERMANY, ²Institute of Nutritional Science, University of Potsdam, Potsdam, GERMANY, ³Dpt. of Biochemistry and Molecular Biology, University of Debrecen, Debrecen, HUNGARY.

572   The Role of MyD88 and TNF-a in the Inflammatory Response in the Middle Ear

S. I. Wasserman, J. Ebmeyer, K. Pak, A. Ryan; Medicine, UCSD, La Jolla, CA.

573   Monitoring of Endotoxin-Induced Pulmonary Inflammation In Vivo in NF-kB Luciferase Transgenic Mice

P. S. Thorne ¹, S. Hadina¹, K. Kulhankova¹, C. Wohlford-Lenane², P. B. McCray², J. P. Weiss³; ¹Occupational & Environmental Health, University of Iowa, College of Public Health, Iowa City, IA, ²Pediatrics, University of Iowa, College of Medicine, Iowa City, IA, ³Internal Medicine and Microbiology, University of Iowa, College of Medicine, Iowa City, IA.

574   Lyso-Phosphatidylserine (Lyso-ps) Generated by Activated Neutrophils Signals in an Autocrine/paracrine Manner Via G2a- And Rho-dependent Pathways

D. L. Bratton ¹, S. C. Frasch¹, K. Zemski-Berry², M. Fessler¹, C. Shearn¹, R. C. Murphy², P. M. Henson¹; ¹Pediatrics, National Jewish Medical and Research Center, Denver, CO, ²Pharmacology, University of Colorado Denver and Health Sciences Center, Aurora, CO.

575   Distribution of IL-13Ra2: Impact of Allergen Exposure and Level of Expression

M. O. Daines ¹, J. A. Masino², A. M. Gibson¹, W. Chen¹, B. A. Walker³, M. R. Warrier¹, Y. Tabata¹, G. K. Khurana Hershey¹; ¹Pediatric Allergy and Immunology, Cincinnati Children's Hospital, Cincinnati, OH, ²Joan C. Edwards School of Medicine, Marshall University, Huntington, WV, ³Washington University in St. Louis, St. Louis, MO.

576   Importance of Leukotrienes in Vulvovaginal Itch and Pain as Evident by Response to Montelukast

L. H. Fisher ¹, N. Kamdar², T. Craig¹, C. MacNeill³; ¹Allergy/Immunology, Penn State Hershey Medical Center, Hershey, PA, ²Obstetrics and Gynecology, University Of Wisconsin, Madison, WI, ³Obstetrics/ Gynecology, Penn State Hershey Medical Center, Hershey, PA.

577   Lack of Association of a New LTC4S Promoter Polymorphism (-1702G>A) with Aspirin-Intolerant Asthma (AIA)

J. H. Choi ¹, J. S. Bae, II², S. H. Kim³, C. H. Suh³, D. H. Nahm⁴, H. S. Park⁴; ¹Dept of Pulmonology and Allergy, Bundang JeSaeng General Hospital, Seongnam-si, Kyunggido, REPUBLIC OF KOREA, ²Dept of Allergy and Rheumatology, Ajou University Hospital, Suwon-si, Kyunggido, REPUBLIC OF KOREA, ³Allegy and Rheumatology, Ajou University Hospital, Suwon-si, Kyunggido, REPUBLIC OF KOREA, ⁴Allergy and Rheumatology, Ajou University Hospital, Suwon-si, Kyunggido, REPUBLIC OF KOREA.

578   Il-10 Regulate Smad Protein Expression in Cultured Airway Epithelial Cells

N. Fueki ¹, H. Sagara², M. Ota², K. Akimoto², T. Okada², K. Sugiyama², M. Fueki¹; ¹Jobu Hospital for respiratory Disease, Maebashi Gunma, JAPAN, ²Department of Pulmonary Medicine and Clinical Immunology, Dokkyo University School of Medicine, Mibu Tochigi, JAPAN.

579   Lipooligosaccharide Inhalation Produces Dose- and Time-Dependant Lung Inflammation and Cytokine Release in Mice

S. Hadina ¹, P. S. Thorne¹, K. Kulhankova¹, P. B. McCray², J. P. Weiss³; ¹Occupational & Environmental Health, University of Iowa, College of Public Health, Iowa City, IA, ²Pediatrics, University of Iowa, College of Medicine, Iowa City, IA, ³Internal Medicine and Microbiology, University of Iowa, College of Medicine, Iowa City, IA.

580   Leukolysin (MMP-25): A Potential Metabolic Marker Airway Inflammation in Asthma

J. B. Sweet; Pulmonary, Allergy & Critical Care, U of MN, Minneapolis, MN.

Poster Session

3212

Sunday, March 05, 2006 9:45 am to 10:45 am

Regulation and Control of Allergic Inflammation

581   Haplotype Structure and Natural Selection in an Olfactory Receptor (OR) Gene on Chromosome 6p Associated with Asthma Susceptibility

E. E. Thompson ¹, C. Murray¹, M. C. Burkart¹, D. Nicolae², Y. Gilad¹, C. Ober¹; ¹Human Genetics, University of Chicago, Chicago, IL, ²Statistics, University of Chicago, Chicago, IL.

582   Novel Small-Molecules Isolated from a Marine Microbial Library Inhibit IL-5 Production In Vitro

W. K. Strangman ¹, D. Broide², W. Fenical¹; ¹Scripps Institution of Oceanography, UC San Diego, La Jolla, CA, ²Medicine, UC San Diego, La Jolla, CA.

583   Therapeutic Effect of Flt3-Ligand in Cockroach Antigen Induced Allergic Airway Inflammation and Airway Hyper-Responsiveness

J. H. Edwan ¹, D. K. Agrawal^1,2; ¹Biomedical Sciences Department, Creighton University School of Medicine, Omaha, NE, ²Medical Microbiology and Immunology Department, Creighton University School of Medicine, Omaha, NE.

584   Persistent Aeroallergen Sensitization at Ages One and Two in the Cincinnati Childhood Allergy and Air Pollution Study

P. H. Ryan ¹, G. K. LeMasters¹, J. E. Lockey¹, G. K. Hershey², M. Villareal¹, D. I. Bernstein¹; ¹University of Cincinnati, Cincinnati, OH, ²Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

585   IL-13 Receptor Alpha 2 Lung-transgenic Mice Displayed Reduced Airway Hyperresponsiveness and Inflammation in a House Dust Mite Challenged Model

W. Chen, C. M. Cunningham, M. O. Daines, M. R. Warrier, A. M. Gibson, G. K. Khurana Hershey; Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

586   The Antioxidants, Glutathione-S-Transferase-Omega1-1 (GST1-1) and Glutathione Peroxidase2 (GPX2), Are Increased in Allergic Airway Inflammation

D. Quarcoo, A. M. Dittrich, M. Krokowski, A. Awagjan, B. Ahrens, E. H. Hamelmann; Pediatric Pneumology and Immunology, Charité University Medicine, Berlin, GERMANY.

587   Functional Alteration of Steroid Responses in Steroid Resistant (SR) Asthma by Increased Glucocorticoid Receptor (GCR) Beta Expression

E. Goleva ¹, L. Li¹, R. J. Martin², D. Y. Leung¹; ¹Pediatrics, National Jewish Medical and Research Ctr., Denver, CO, ²Medicine, National Jewish Medical and Research Ctr., Denver, CO.

588   Comparison of Cellular Inflammation and Molecular Activation in Asthma and Eosinophilic Bronchitis

V. DEL POZO ¹, C. Seoane¹, M. Fernández -Nieto², J. Sastre², C. Lahoz¹, S. Quirce², B. Sastre¹; ¹Immunology, Fundación Jimenéz Diáz, Madrid, SPAIN, ²Allergy, Fundación Jimenéz Diáz, Madrid, SPAIN.

589   Presence of Eosinophils in the Nasal Secretion during Acute Upper Respiratory Tract Infection (URI) in Young Children Predicts Wheeze in Subsequent 2 Months

M. Shinohara ^1,2, H. Wakiguchi¹, H. Saito², K. Matsumoto²; ¹Department of Pediatrics, Faculty of Medicine, Kochi University, Kochi, JAPAN, ²Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN.

590   The PPARg Agonist Ciglitazone Upregulates GILZ, a Novel Anti-inflammatory Protein, in Airway Epithelial Cells

A. L. Wagelie-Steffen ¹, J. Eddleston², J. Hirshbach², B. L. Zuraw²; ¹Medicine, Division of Allergy / Immunology, University of California, San Diego, San Diego, CA, ²Medicine, University of California, San Diego and Veteran's Medical Research Foundation, San Diego, CA.

591   Modulation of Immune Response by a Novel Kaliuretic Peptide

S. A. Shirley ¹, R. Singham¹, X. Kong², R. F. Lockey², S. S. Mohapatra²; ¹Medical Microbiology and Immunology, University of South Florida, Tampa, FL, ²Internal Medicine, University of South Florida, Tampa, FL.

592   Eicosanoids in Induced Sputum (IS): Influence of Aspirin Hypersensitivity and Atopy

A. Kania, E. Nizankowska, G. Bochenek, A. Gielicz, A. Szczeklik; Department of Medicine, Jagiellonian University School of Medicine, Krakow, POLAND.

593   The Induction of Distinct Immunologic and Morphologic Changes in a Model of Chronical Allergen Exposure

B. Ahrens, A. Dittrich, D. Quarcoo, E. Hamelmann; Department of Pediatric Pneumology and Immunology, Charité University Medicine, Berlin, GERMANY.

594   Identification & Characterisation of Proteins Associated with Allergic Airways Disease (AAD)

C. M. Dixon ¹, J. Christie², K. I. Matthaei¹, P. S. Foster^1,3, D. C. Webb¹; ¹Division of Molecular Biosciences, John Curtin School of Medical Research, Canberra, AUSTRALIA, ²School Proteomics and Microarray Facility, Research School of Biological Sciences, Canberra, AUSTRALIA, ³Asthma, Allergy and Inflammation Research Centre, University of Newcastle, Newcastle, AUSTRALIA.

595   Pathophysiology of Late Onset Atopic Asthma in a Murine Model

P. J. Busse ¹, T. Zhang², S. Termanini², K. Srivastava², B. Schofield³, X. Li²; ¹Medicine, Div of Clinical Immunology, Mount Sinai School of Medicine, New York, NY, ²Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY, ³Environmental Health Sciences, Bloomberg School of Public Health, Baltimore, MD.

596   The Role of Adipokines in Childhood Asthma and Their Effect on Bronchial Hyperresponsiveness

K. Kim ¹, Y. Shin², E. Kim¹, G. Jang³, M. Sohn¹, K. Kim¹; ¹Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, Pochon CHA University College of Medicine, Seoul, REPUBLIC OF KOREA, ³Department of Pediatrics, NHIC Ilsan Hospital, Seoul, REPUBLIC OF KOREA.

597   Genome-wide Gene Expression Analysis of the Human Intestinal Epithelial Cells after Stimulation with Lactic Acid Bacteria

S. Toki ^1,2, S. Kagaya¹, M. Shinohara¹, T. Matsumoto², Y. Takahata², H. Saito¹, K. Matsumoto¹; ¹Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN, ²R&D center, Nippon meet packers INC., Tsukuba, JAPAN.

598   Blood Collection, Processing Methods and Maternal Characteristics and the Potential Impact on Study Results in a Longitudinal Birth Cohort Study

K. A. Roberg ¹, K. T. Sullivan-Dillie¹, K. S. Anklam¹, L. A. Rosenthal¹, D. F. DaSilva¹, C. J. Tisler¹, T. E. Pappas¹, R. E. Gangnon², J. E. Gern¹, R. F. Lemanske, Jr.¹; ¹Allergy Asthma Research, UW Medical School, Madison, WI, ²Biostatistics and Medical Informatics and Population Health Sciences, UW Madison, Madison, WI.

599   The Effect of Etanercept on the Human Cutaneous Allergic Response

E. R. Conner ¹, M. Brummet¹, C. Bickel¹, L. Bankova¹, L. McGirt¹, T. Meusel¹, S. Stevens², B. S. Bochner¹, L. A. Beck¹; ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Amgen, Thousand Oaks, CA.

600   In Vivo Efficacy in Mouse Asthma Model of Basic Fibroblast Growth Factor

I. Lee ¹, M. Son¹, J. Jeong¹, B. Kim¹, S. Kang¹, Y. Kim²; ¹DONG-A PHARM. CO., LTD, Yongin, REPUBLIC OF KOREA, ²College of medicine, Seoul National University, Seoul, REPUBLIC OF KOREA.

601   Development of Autoreactive Antibodies in Allergic Mice after Chronic Respiratory Allergen Exposure

H. Garn ¹, I. Mittermann², R. Valenta², H. Renz¹; ¹Department of Clinical Chemistry and Molecular Diagnostics, Medical Faculty, Philipps University of Marburg, Marburg, GERMANY, ²Division of Immunopathology, Department of Pathophysiology, Center of Physiology and Pathophysiology, Medical University of Vienna, Vienna, AUSTRIA.

602   History of Parental Allergy and Asthma as Predictors of Allergic Sensitization in their Offspring

E. L. Anderson ¹, M. D. Evans², D. F. G. DaSilva¹, T. E. Pappas¹, L. E. Pleiss¹, K. A. Roberg¹, K. T. Sullivan Dillie¹, C. J. Tisler¹, R. E. Gangnon², J. E. Gern³, R. F. Lemanske, Jr.³; ¹Pediatrics, UW Medical School, Madison, WI, ²Biostatistics and Medical Informatics and Population Health Sciences, UW Medical School, Madison, WI, ³Medicine, UW Medical School, Madison, WI.

603   Asthma Symptoms Under Two Years Old after Suffering Meconium Aspiration Syndrome

F. Vazquez-Nava; Unidad de Investigación en Epidemiología Clínica, Social Securirty Mexican Institute. Universidad Autonoma de Tamaulipas., Ciudad Madero, MEXICO.

604   Atopy and Sensitization to Inhalant Allergens may be Risk Factor for Bronchial Hyperresponsiveness but not Pulmonary Function

J. Kim ¹, H. Kim², S. Lee², B. Kim², H. Seo², S. Hong²; ¹Ulsan University Hospital, Ulsan, REPUBLIC OF KOREA, ²Pediatrics, Asan Medical Center, Ulsan University College of Medicine, Seoul, REPUBLIC OF KOREA.

605   10-6M (RR)-Formoterol, but Not (SS)-Formoterol or (S)/(R)-Albuterol, Inhibits RANTES Secretion by RSV Antigen-Stimulated Confluent Human Alveolar Epithelial Cells (cA549)

G. Puglisi, A. Capetandes, M. Frieri; Division of Allergy Immunology, Nassau University Medical Center, East Meadow, NY.

606   Chinese Herbal Extract Glycyrrhiza uralensis (Gu), in the Absence or Presence of IL-1b, Decreases Nitrite Production and Proliferation of Human Type II Alveolar Epithelial Cells (A549)

A. R. Narayan ¹, Y. C. Huang¹, Y. H. Zhang², X. M. Li³, M. Frieri¹; ¹Division of Allergy & Immunology, Nassau University Medical Center, East Meadow, NY, ²Department of Pathology, Nassau University Medical Center, East Meadow, NY, ³Division of Pediatric Allergy & Immunobiology, Mount Sinai School of Medicine, New York, NY.

607   Cell Death and Survival in Response to Immunostimulatory Sequence Oligodeoxynucleotides Treatment in a Murine Model of Allergic Asthma

Y. Higaki^1,2, J. M. Zubeldia ¹, L. Conejero^1,2, M. L. Baeza¹, I. Varela-Nieto²; ¹Allergy Department, Hospital Gregorio Maranon, Madrid, SPAIN, ²Instituto Investigaciones Biomedicas Alberto Sols, Madrid, SPAIN.

608   Association between Systemic and Local Immune Response Parameters in Children with Bronchial Asthma

A. Nakonechna ¹, T. Umanets², V. Lapshin², A. R. D. van Bergen³; ¹National Medical University, Kiev, UKRAINE, ²Institute of Pediatry, Obstetrics and Gynaecology, Kiev, UKRAINE, ³Novidec Ltd, Neston, UNITED KINGDOM.

609   Zileuton Provides Significant Improvement in Asthma Symptoms and b-agonist and Rescue Medication Use Compared to Placebo in Asthma Patients with Reduced or Low Lung Function

R. A. Nathan ¹, B. M. Prenner², J. A. Bernstein³, K. Walton-Bowen⁴; ¹Asthma and Allergy Associates, P.C. and Research Center, Colorado Springs, CO, ²Allergy Associates Medical Group, San Diego, CA, ³Department of Internal Medicine, University of Cincinnati Medical Center, Cincinnati, OH, ⁴Clinical Operations, Biostatistical Analysis, and Reporting, Critical Therapeutics, Inc., Lexington, MA.

610   Effects of Electric Fields on Pollen Rupture

V. Vaidyanathan ¹, A. G. Miguel¹, P. E. Taylor¹, R. C. Flagan¹, M. M. Glovsky²; ¹Chemical Engineering, CalTech, Pasadena, CA, ²Huntington Asthma and Allergy Center, HMRI, Pasadena, CA.

611   Plasmacytoid Dendritic Cells (PDC) and B Cells Are the Origin of IL-10 in Human PBMC Stimulated by Immunostimulatory Sequence Oligodeoxynucleotides (ISS-ODN)

J. Lee ¹, H. Park², J. Bahn¹, Y. Kim², S. Cho², K. Min², Y. Kim², K. Jung¹; ¹Internal Medicine, College of medicine, Hallym University, Chunchon, REPUBLIC OF KOREA, ²Internal Medicine, Seoul National University College of Medicine, Seoul, REPUBLIC OF KOREA.

612   Antibody Production Against rPhl p 1 and rPhl p 5 After The Immunization of Rabbits with a Depigmented and Polymerized Extract of Phleum Pratense

M. Casanovas, M. Gallego, E. Fernández-Caldas; Laboratorios LETI S.L., Tres Cantos, SPAIN.

613   Expression of Acidic Mammalian Chitinase in Cord Blood Mononuclear Cells

M. R. Goldberg, O. Nadiv, N. Luknar-Gabor, Y. Katz; Allergy&Immunology, Assaf Harofeh Medical Center, Beer Yaakov, ISRAEL.

614   Palatal Itching as an Indicator of Atopy to Pollens

E. K. Dicken, B. Miller; University of Kentucky, Lexington, KY.

615   Bronchial Remodeling: Pathologic Findings of Whole Bronchial Tree in a Case of Chronic Bronchial Asthma

Y. W. Lee ¹, H. S. Chung¹, J. H. Park¹, J. W. Park^1,2, S. H. Cho³, C. S. Hong^1,2; ¹Internal Medicine, Yonsei University, College of Medicine, Seoul, REPUBLIC OF KOREA, ²Institute of Allergy, Yonsei University, College of Medicine, Seoul, REPUBLIC OF KOREA, ³Pathology, Yonsei University, College of Medicine, Seoul, REPUBLIC OF KOREA.

616   MMP-9/TIMP-1 Ratio in Confluent Human Alveoloar Epithelial Cells (cA549) Stimulated by D. Pteronyssinus

J. Zimmermann, A. Capetandes, M. Frieri; Nassau University Medical Center, East Meadow, NY.

617   Persistence of Airway Hyper-Responsiveness (AHR) after Resolution of Bronchial Mucosal Inflammation Following Allergen Inhalation Challenge in Mild Asthmatics

H. H. Kariyawasam, M. Aizen, J. Barkans, D. S. Robinson, A. B. Kay; National Heart & Lung Institute, Imperial College, London, UNITED KINGDOM.

618   Association between Genetic Variations in FGF receptors and Airway Hyperresponsiveness

S. Sohn ¹, H. Kwon¹, K. Kim¹, C. Park¹, H. Kim¹, S. Kim¹, H. Park¹, H. Park², Y. Jeong³, S. Kim¹, Y. Jang¹, Y. Kim¹, S. Cho¹, K. Min¹, Y. Kim¹; ¹Internal Medicine, Seoul National University Hospitial, Seoul, REPUBLIC OF KOREA, ²Internal Medicine, Busan National University Hospitial, Busan, REPUBLIC OF KOREA, ³Internal Medicine, Kyeongsang National University Hospitial, Jinju, REPUBLIC OF KOREA.

Poster Session

3213

Sunday, March 05, 2006 9:45 am to 10:45 am

Immunotherapy Clinical Efficacy and Outcomes

619   High dose SLIT with a Juniperus Ashei Extract Improves Quality of Life in Patients with Cypress Pollinosis

V. Di Rienzo ¹, S. Pucci², A. Romano³, S. D'Alò², C. Incorvaia⁴, F. Frati⁵; ¹Allergy Center, ASL, Latina, ITALY, ²Allergy Center, General Hospital, Civitanova Marche, ITALY, ³Allergy Center, Cattolica University, Roma, ITALY, ⁴Allergy/Rheumatology, ICP Hospital, Milan, ITALY, ⁵Medical Department, Stallergenes Italy, Milan, ITALY.

620   Novel Amb a 1 CpG Oligodeoxyribonucleotide Conjugate Ragweed Vaccine Administered to Children

A. S. Nayak ¹, I. Tripathy², D. Levitt³; ¹Peoria School of Medicine, University of Illinois, Normal, IL, ²Clinical Research of the Ozarks, Inc.-Rolla, Rolla, MO, ³Dynavax Tchnologies, Inc., Berkeley, CA.

621   Safety of Home Immunotherapy

W. V. Filley ¹, C. E. Aston², R. E. Coifman³, J. R. Claflin¹, D. L. Kough¹, P. J. Mills¹; ¹OK Allergy Asthma Clinic, Inc., Oklahoma City, OK, ²OUHSC-GCRC, Oklahoma City, OK, ³Allergy & Asthma of South Jersey, P.A., Millville, NJ.

622   Can Nasal ECP Help to Predict Clinical Outcome of Specific Immunotherapy in Mite-allergic Rhinitis Patients

M. A. R. Branco-Ferreira ¹, A. Spinola-Santos¹, M. Pereira-Santos², M. Palma-Carlos³, M. A. Pereira-Barbosa¹, A. G. Palma-Carlos³; ¹Unidade de Imunoalergologia, Hospital de Santa Maria, LISBON, PORTUGAL, ²Faculdade de Medicina de Lisboa, LISBON, PORTUGAL, ³CHIUL, LISBON, PORTUGAL.

623   National Utlization Rates of Allergen Immunotherapy in the Medicare Population

D. P. Woodmansee ¹, C. Chang², M. K. Wolfson¹, M. S. Shaker¹, D. C. Goodman²; ¹Section of Allergy and Clinical Immunology, Dartmouth-Hitchcock Medical Ctr, Lebanon, NH, ²Center for the Evaluative Clinical Sciences, Dartmouth Medical School, Hanover, NH.

624   Sublingual Immunotherapy Reduce Allergic Symptoms in a Mouse Model of Rhinitis

J. Brimnes, J. KIldsgaard, H. Jacobi, K. Lund; Experimental Immunology, ALK-Abello, Hoersholm, DENMARK.

625   Community Based Experience with Cluster Immunotherapy

R. P. Harvey, J. Poole, K. Beaudry, D. Soteres, L. Headrick, W. Silvers; Allergy Asthma Colorado, Denver, CO.

626   Evolution of Skin Prick Tests During Long Term Specific Immunotherapy

A. G. Palma-Carlos, M. Palma-Carlos; Immunotherapy, CAIC - Clinical Allergy Immunology Center, Lisbon, PORTUGAL.

627   A 3-Year Randomized Controlled Study with Sublingual Immunotherapy in Mite-Induced Respiratory Allergy

G. Passalacqua ¹, C. Lombardi², R. Ariano³, M. Pasquali¹, I. Baiardini¹, A. Giardini⁴, G. Maiani⁴, M. Bruno⁵, P. Falagiani⁵, G. W. Canonica¹; ¹Allergy & Respiratory Diseases Dept of Internal Medicine, Genoa University, Genova, ITALY, ²Pneumoallergology Unit, Ospedale S. Orsola, Brescia, ITALY, ³Internal Medicine Division, Bordighera Hospital, Bordighera, ITALY, ⁴Salvatore Maugeri, IRCCS, Pavia, ITALY, ⁵Lofarma SpA, Milano, ITALY.

628   Quantitative Assessment of the Compliance with Sublingual Immunotherapy in Real Life: Easy Project

G. Senna ¹, A. Musarra², S. Pecora³, G. Passalacqua⁴; ¹Allergy Unit, Verona General Hospital, Verona, ITALY, ²Allergy Unit, National Healthcare, Reggio Calabria, ITALY, ³ALK-Abellò, Lainate (Milan), ITALY, ⁴Allergy & Respiratory Diseases Dept of Internal Medicine, Genoa University, Verona, ITALY.

629   Effectiveness and Satisfaction with Immunotherapy of Patients with Allergic Rhinitis Unsatisfied with Free Optimal Pharmacotherapy.

J. E. Gereda; Alergia e Inmunologia, Clinica Ricardo Palma, Lima, PERU.

630   Seasonal Sublingual Versus Subcutaneous Immunotherapy for Juniper Pollenosis

D. Cooke; Allergy and Asthma Specialists, Durango, CO.

631   Assessment of a New Treatment Schedule in Sublingual Immunotherapy. A Randomised Double-Blind Placebo-Controlled Multicentre Study

M. BOQUETE ¹, F. RODRIGUEZ², A. TABAR³, D. IBAÑEZ⁴, A. NIETO⁵, F. TORRE-MARTINEZ⁶; ¹ALLERGY, HOSPITAL XERAL CALDE, LUGO, SPAIN, ²ALLERGY, HOSPITAL MARQUES DE VALDECILLA, SANTANDER, SPAIN, ³ALLERGY, HOSPITAL VIRGEN DEL CAMINO, PAMPLONA, SPAIN, ⁴ALLERGY, HOSPITAL NIÑO JESUS, MADRID, SPAIN, ⁵ALLERGY, HOSPITAL LA FE, VALENCIA, SPAIN, ⁶ALK-ABELLO, S.A., MADRID, SPAIN.

Poster Session

3214

Sunday, March 05, 2006

9:45 am to 10:45 am

Immunogenetics

632   Gene Transcripts of Peripheral Blood as Potential Biomarkers for Allergic Changes in Upper Airways

D. N. Grigoryev ¹, S. F. Ma², S. Q. Ye², J. G. N. Garcia², K. C. Barnes¹; ¹Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD, ²Center for Integrated Sciences, University of Chicago, Chicago, IL.

633   Ethnic Differences in Frequencies of Single Nucleotide Polymorphisms for Glutathione S-Transferase (GST) and IL13

K. M. Donohue ¹, D. Tang¹, D. Chau¹, H. Andrews¹, R. Chen², S. Yadavalli², F. Perera¹, S. Chanock², R. L. Miller¹; ¹CCEH Columbia University, New York, NY, ²National Cancer Institute, Bethesda, MD.

634   Anti-MHC Class II Alpha Chain Antibodies Block Staphylococcal Enterotoxin B Induced T-cell Proliferation

M. M. Sen ¹, R. Govindarajan², C. S. David²; ¹Molecular Immunology, Cincinnati Children's Hospital, Cincinnati, OH, ²Immunology, Mayo Clinic, Rochester, MN.

635   Leukolysin and Asthma

M. N. Blumenthal, G. Lind, R. Willaert, M. Miller, R. King, W. Oetting, D. Pei; University of Minnesota, Minneapolis, MN.

636   CTLA-4 Gene Exon-1 +49 A/G Polymorphism is not Associated with Susceptibility to Autoimmune Disease in Patients with Common Variable Immune Deficiency

A. K. Knight ¹, D. Serrano¹, Y. Tomer², C. Cunningham-Rundles¹; ¹Clinical Immunology, Mount Sinai Medical Center, New York, NY, ²Division of Endocrinology, Mount Sinai Medical Center, New York, NY.

637   TNFRSF1A Mutation in a Heterozygous Carrier of MEFV P369S: Case Study Of Periodic Fever Syndrome

E. Hahn ¹, A. White²; ¹Department of Pediatrics, Division of Allergy and Pulmonary Medicine, Washington University, St. Louis Children's Hospital, St.Louis, MO, ²Department of Pediatrics, Division of Rheumatology and Immunology, Washington University School of Medicine, St. Louis Children's Hospital, St.Louis, MO.

638   The Association of Atopic Diseases with Hla Status

A. Bozek ¹, J. Jarzab¹, J. Krajewska², L. Dymek³, A. Dymek³; ¹Clinical Department of Internal Medicine and Dermatology, Silesian University School of Medicine, Zabrze, POLAND, ²Institute Oncology, M.Sklodowska-Curie Memorial Cancer Center, Gliwice, POLAND, ³Medical Center, Strzelce Opolskie, POLAND.

Poster Session

3215

Sunday, March 05, 2006

9:45 am to 10:45 am

Rhinosinusitis/Conjunctivitis Diagnosis and Treatment

639   Nasal Nitric Oxide (NNO) in Patients with Allergic Rhinitis and Healthy Volunteers Following Pollen Exposure in an Environmental Challenge Chamber (ECC)

J. M. Hohlfeld ¹, M. Larbig¹, I. Paczkowski¹, H. Hecker², N. Krug¹, a. ALMA-Study Group³; ¹Fraunhofer ITEM, Hannover, GERMANY, ²Hanover Medical School, Hannover, GERMANY, ³Ruhr-University, Bochum, GERMANY.

640   The Effect of Environmental Control and Intranasal Corticosteroid in Brazilian Children with Persistent Allergic Rhinitis

A. P. Reis; Immunology, ICB-UFMG, Belo Horizonte, BRAZIL.

641   Nasal Flow Cytometry in the Diagnosis of Persistent Allergic Rhinitis and Persistent Idiopathic Non-Allergic Rhinitis

S. Lopez¹, C. Rondon², R. R-Pena¹, C. Mayorga¹, M. J. Torres², C. Antunez¹, J. J. Romero², J. A. Cornejo-Garcia¹, M. Blanca ²; ¹Research Laboratory, Carlos Haya Hospital, Malaga, SPAIN, ²Allergy Service, Carlos Haya Hospital, Malaga, SPAIN.

642   Combination Therapy with Montelukast and Antihistamines (desloratadine or Levocetirizine) Improves Quality of Life in Patients with Persistent Allergic Rhinitis: a Double Blind Placebo Controlled Study

M. Ciebiada¹, M. Górska-Ciebiada¹, L. M. DuBuske², P. Gorski ¹; ¹Department of Pneumonology and Allergy, Medical University of Lodz, Lodz, POLAND, ²Immunology Research Institute of New England, Gardner, MA.

643   Prescription Medication Use Following Rhinitis Diagnosis: An Examination of Pharmacy Claims in the Integrated Healthcare Information Services (IHCIS) Database

M. A. Corrao, D. W. Clark, R. A. Fleenor, K. J. Davis; Worldwide Epidemiology, GlaxoSmithKline, Research Triangle Park, NC.

644   Allergic Responses Induced by Grass Pollen in an Environmental Challenge Chamber (ECC) Reflect Changes During Seasonal High Pollen Counts in Allergic Rhinitis Patients

N. Krug ¹, T. Holland-Letz², E. Wierenga³, R. van Ree⁴, A. Hüsing², M. Larbig¹, J. M. Hohlfeld¹, A. Bufe², a. ALMA-Study Group²; ¹Fraunhofer ITEM, Hannover, GERMANY, ²University of Bochum, Bochum, GERMANY, ³University of Amsterdam, Amsterdam, THE NETHERLANDS, ⁴Sanquin Research, Amsterdam, THE NETHERLANDS.

645   Safety and Efficacy of Olopatadine Hydrochloride Nasal Spray 665 mcg (Patanase^® Nasal Spray) in Patients with Perennial Allergic Rhinitis

B. Q. Lanier; North TX Institute for Clinical Trials, Fort Worth, TX.

646   Nasolacrimal Reflux - A New Clinical Finding

N. W. Chang¹, T. M. Foss¹, T. Y. Chang¹, K. C. Chang ¹, M. J. Barrett², J. M. Carney¹, H. D. Nguyen¹; ¹Asthma Allergy Centre, Tigard, OR, ²Allergy Department, Kaiser Permanente Northwest Region, Portland, OR.

647   Effect of Nasal Corticosteroids on Adenoidal Hypertrophy in Children with Non-Allergic Rhinitis

S. Kung, E. Yousef, S. J. McGeady; Division of Allergy and Immunology, Thomas Jefferson University, Philadelphia, PA.

648   MUC8 as a Ciliated Cell Marker in Human Nasal Epithelium

C. Kim ^1,2, J. Yoon^1,2; ¹Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA, ²The Airway Mucus Institute, Seoul, REPUBLIC OF KOREA.

649   The Importance of Specific IgG, IgE Antibodies to Retinal S Protein, Type II Collagen and Alternaria in Idiopathic Central Serous Chorioretinopathy

J. C. Muino ¹, R. Smith², J. D. Luna², M. D. Romero³, M. Ferrero³, C. P. Juárez²; ¹Medicine III - UHMI N° 4 - Hospital Misericordia, Facultad de Ciencias Médicas Universidad Nacional de Córdoba, Cordoba, ARGENTINA, ²Oftalmología, Fundación Ver, Cordoba, ARGENTINA, ³Inmunología, LIIDO, Cordoba, ARGENTINA.

650   Esterases Involved in the Metabolism of Ciclesonide (CIC) in Human Nasal Epithelial Cells (HNEC)

M. A. Wingertzahn¹, H. Sato ², R. Nave³, T. Nonaka,², T. Mochizuki², S. Takahama², S. Kondo²; ¹Altana Pharma, Florham Park, NJ, ²Teijin Institute for Biomedical Research, Tokyo, JAPAN, ³Altana Pharma, Konstanz, GERMANY.

651   Effect of Mometasone Furoate Nasal Spray Therapy on Nasal Congestion and Sleep-Related Outcomes in Rhinosinusitis and Nasal Polyposis

G. M. Gottschlich; New Horizons Clinical Research, Cincinnati, OH.

652   Reversibility of Desisobutyryl-Ciclesonide Conversion to Fatty Acid Conjugates

M. Wingertzahn¹, T. Nonaka², T. Mochizuki², H. Sato ², S. Kondo²; ¹Altana Pharma, Florham Park, NJ, ²Teijin Institute for Biomedical Research, Tokyo, JAPAN.

653   Efficacy and Safety of Ciclesonide Nasal Spray for the Treatment of Seasonal Allergic Rhinitis

P. H. Ratner ¹, J. H. van Bavel², P. Darken³, N. Hall⁴, T. Shah⁵, M. A. Wingertzahn⁶; ¹Sylvana Research, San Antonio, TX, ²Allergy & Asthma Associates, Austin, TX, ³Director, Biostatistics and Data Management, Altana Pharma, Florham Park, NJ, ⁴Associate Director, Biostatistics, Altana Pharma, Florham Park, NJ, ⁵Scientific and Clinical Development, Altana Pharma, Florham Park, NJ, ⁶Clinical Project Head, Altana Pharma, Florham Park, NJ.

654   A Double-Blind Comparison of Efficacy of 0.1% Tacrolimus Ophthalmic Ointment and 2% Cyclosporine Eye Drop Vernal Keratoconjunctivitis (vkc)

P. Labcharoenwongs ¹, W. Durongpisitkul², P. Dumrongkigchaiporn³, O. Jirapongsananuruk¹, N. Visitsunthorn¹, P. Kosrirukvongs⁴, W. Booranapong⁴, P. Vichyanond¹; ¹Pediatric, Siriraj hospital, Bangkok, THAILAND, ²Pediatric, Police general hospital, Bangkok, THAILAND, ³Pediatric, Bangkok Pattaya hospital, Chonburi, THAILAND, ⁴Opthalmology, Siriraj hospital, Bangkok, THAILAND.

655   Effect of Anti-Allergic Herbal Extract, SA-2121, on the Development of Allergic Conjunctivitis

J. Davidson ¹, S. Baik¹, Z. Yao², R. Martin², C. K. Oh¹; ¹Harbor-UCLA Medical Center, Torrance, CA, ²Tanox Inc., Houston, TX.

656   House Dust Mite Allergy causing Otitis Externa

R. S. Kaulsay ¹, P. P¹, Y. Yeow¹, L. Rampal², I. Hidayah³; ¹Dept of ENT Surgery, University Putra Malaysia, Kuala Lumpur, MALAYSIA, ²Dept of Community Health Medicine, University Putra Malaysia, Kuala Lumpur, MALAYSIA, ³Dept of Biomedical Science, University Technology Malaysia, Kuala Lumpur, MALAYSIA.

657   Serum Leukocyte Protease Inhibitor Levels in Patients with Uveitis

V. E. Reviglio ¹, M. D. Romero², M. Ferrero³, J. D. Luna¹, C. P. Juárez¹, J. C. Muiño⁴; ¹Oftalmología, Fundación Ver, Cordoba, ARGENTINA, ²Inmuología, LIIDO, Cordoba, ARGENTINA, ³Inmunología, LIIDO, Cordoba, ARGENTINA, ⁴Medicina III - UHMI N° 4, Facultad de Ciencias Médicas Universidad Nacional de Córdoba, Cordoba, ARGENTINA.

658   Sensorineural Hearing Loss Due to Allergic Rhinitis. Case Report

C. Lombardi ¹, A. Tansini², G. Passalacqua³; ¹Pneumoallergology Unit, S. Orsola Hospital, Brescia, ITALY, ²Radiology Unit, S. Orsola Hospital, Brescia, ITALY, ³Allergy & Respiratory Diseases Dept of Internal Medicine, Genoa University, Genova, ITALY.

Poster Session

3216

Sunday, March 05, 2006 9:45 am to 10:45 am

Primary Immunodeficiency 2

659   Idiopathic Cd4 + Lymphocytopenia Associated with Cryptococcal Meningitis in One Pediatric Patient.

M. R. SANCHEZ, G. GUIDOS, J. G. HUERTA; Allergy and immunology, Instituto Nacional de Pediatria, Mexico city, MEXICO.

660   CVID and Severe Persistent Asthma-A Case Report

L. B. Moreno; North Shore-Long Island Jewish Health System, corona, NY.

661   Adenosine Deaminase Deficiency and Storage Pool Deficiency: A Case report

C. S. Taylor ¹, M. Patruzzi², M. Ballow³; ¹Allergy, SUNY Buffalo, Amherst, NY, ²Hematology, SUNY Buffalo, Buffalo, NY, ³Allergy, SUNY Buffalo, Buffalo, NY.

662   Cholecystitis and Pancreatitis from Obstructing Lymphadenopathy in a Patient with CVID

E. L. Pratt, L. H. Fisher, S. Chegini, J. Gibbs, G. Ghaffari, J. Larson, T. J. Craig; Pulmonary/Allergy/Critical Care, Penn State Milton S. Hershey Medical Center, Hershey, PA.

663   Toddler Boy with Recurrent Abscesses from Infancy Secondary to G6PD Deficiency

D. Paek ¹, M. Singla²; ¹Wake Forest University School of Medicine, Winston-Salem, NC, ²Section on Pulmonary, Critical Care, Allergy and Immunologic Diseases, Wake Forest University School of Medicine, Winston-Salem, NC.

664   Recurrent Pneumonia Associated with Hydroxychloroquine

J. G. Gibbs, E. L. Pratt, L. H. Fisher, S. F. Chegini, T. J. Craig; Pulmonary, Allergy, Critical Care, Milton S. Hershey Medical Center, Hershey, PA.

665   Deficient Humoral Response to Haemophilus Influenza Type b Meningitis In a 7 Month Old Vaccinated Child

D. A. Ramirez ¹, V. N. Madrigal¹, W. Blouin², M. Laufer³, V. P. Hernandez-Trujillo²; ¹Miami Children's Hospital, Miami, FL, ²Allergy & Immunology, Miami Children's Hospital, Miami, FL, ³Infectious Disease, Miami Children's Hospital, Miami, FL.

666   Successful Use of Daily Intravenous Infusion of C1 INH Concentrate (Berinert P^®) in the Treatment of a Hereditary Angioedema (HAE) Subject with Renal and Respiratory Failure

W. H. Yang; Medicine, University of Ottawa, Ottawa, ON, CANADA.

667   Membranous Glomerulonephritis in an Individual with X-linked Agammaglobulinemia on Intravenous Immunoglobulin

L. M. Endo ¹, J. Foote², D. G. Warnock³, W. J. Cook⁴, H. W. Schroeder, Jr.⁵; ¹Allergy and Immunology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Nephrology, University of Alabama at Birmingham, Birmingham, AL, ⁴Clinical Pathology, University of Alabama at Birmingham, Birmingham, AL, ⁵Developmental & Clinical Immunology, University of Alabama at Birmingham, Birmingham, AL.

668   Idiopathic Pulmonary Hemosiderosis in a Patient with CVID

C. Kelly; Pediatrics, Eastern Virginia Medical School, Norfolk, VA.

669   Transient Hypogammaglobulinemia of Infancy, a Possible Autosomal Dominant Inheritance Pattern in Certain Families

S. R. Patel ¹, R. Roberts²; ¹Department of Medicine, University of California at Los Angeles, Los Angeles, CA, ²Department of Pediatrics, University of California at Los Angeles, Los Angeles, CA.

670   The Sisters Who Would not Inflame - Two Cases of Suspected Irak-4 Deficency

S. S. Mehr, J. Smart, M. Tang; Immunology Department, Royal Children's Hospital, Melbourne, Victoria, Melbourne, Victoria, AUSTRALIA.

671   Two Patients With Idiopathic CD4 (+) T-lymphocytopenia Presenting With Opportunistic Infections

N. Gupta ¹, D. Alcid², R. Sharma³, B. Silverman¹, A. T. Schneider¹; ¹Dept. of Allergy & Immunology, Long Island College Hospital, Brooklyn, NY, ²Infectious Disease, Drexel University College of Medicine, New Brunswick, NJ, ³Dept. of Internal Medicine, Robert Wood Johnson Medical School-UMDNJ, New Brunswick, NJ.

672   Neutropenia and Hypogammaglobulinemia in Propionic Acidemia

M. H. Land, R. L. Roberts; Department of Pediatrics, UCLA Medical Center, Los Angeles, CA.

673   Purine Nucleoside Phosphorylase Deficiency in Saudi Arabia

A. A. A. Alangari ¹, A. Al-Harbi², A. Alghonaium², M. Hershfied³; ¹Pediatrics, King Saud University, Riyadh, SAUDI ARABIA, ²Pediatrics, King Faisal Specialist Hospital, Riyadh, SAUDI ARABIA, ³Pediatrics, Duke University Medical Center, Durham, NC.

674   Combined Chronic Granulomatous Disease (CGD) and G-6-PD Deficiency in an Infant

C. W. Mayer ¹, S. Bahgash¹, J. A. Bocchini, Jr.², S. L. Bahna¹; ¹Allergy/Immunology Section, LSUHSC, Shreveport, LA, ²Pediatric Infectious Disease Section, LSUHSC, Shreveport, LA.

675   Chronic Granulomatous Disease Presenting with CD4 Lymphopenia

R. Tachdjian, R. L. Roberts; Allergy, Immunology, Rheumatology, UCLA School of Medicine, Los Angeles, CA.

676   Recurrent Meningitis Secondary to Metronidazole used as Helicobacter Eradication Therapy

S. Khan¹, B. Sharrack², W. A. C. Sewell ¹; ¹Path Links Immunology, North Lincolnshire, UNITED KINGDOM, ²Lincoln County Hospital, Lincoln, UNITED KINGDOM.

677   Subcutaneous Versus Intravenous Immunoglobulin for the Treatment of DiGeorge Syndrome Related Hypogammaglobulinemia

S. MacLeish, R. Hostoffer, Jr.; Pediatrics, Case Western Reserve University, Cleveland, OH.

678   An Uncommon Presentation of Chronic Diarrhea and Common Variable Immunodeficiency Improved with IVIG Therapy

S. J. McEldowney, M. H. Moss; Allergy and Clinical Immunology, University of Wisconsin, Madison, WI.

679   Diagnosis of Common Variable Immunodeficiency in a Patient with Evan's Syndrome

K. R. Lowe, C. P. Mikita, M. M. Klote, M. R. Nelson; Allergy/Immunology, Walter Reed Army Medical Center, Washington, DC.

680   Rare Intestinal Manifestation in a Patient with Common Variable Immunodeficiency and Strongyloidiasis

P. Giavina-Bianchi, F. Collet e Silva, D. Birolini, J. Kalil, L. V. Rizzo; Clinical Immunology and Allergy, FMUSP, São Paulo, BRAZIL.

681   T Lymphocyte Profile in Schwachman Diamond Syndrome

R. Sullivan, N. Y. Olson; Pediatrics, University of Kansas, Kansas City, KS.

682   An Unusual Immunoglobulin Profile in an Adult Patient

R. Ayuso; Allergy and Clinical Immunology, Mount Sinai Medical Center, NY, NY.

683   Ulcerative Colitis in a Pediatric Patient with IgA Deficiency

A. Kounavis ¹, T. B. Fausnight²; ¹Pediatrics, Penn State Children's Hospital, Hershey, PA, ²Pediatric Asthma and Immunology, Penn State Children's Hospital, Hershey, PA.

684   Skeletal Abnormalities Associated with DiGeorge Syndrome: Report of an Unusual Case

S. J. Khiani ¹, J. A. Kleinfeld², K. J. Khiani³, A. T. Gewurz²; ¹Immunology/Microbiology (RUMC) & Pediatrics (SHCC), Rush University Medical Center-Stroger Hospital of Cook County A/I Program, Chicago, IL, ²Immunology/Microbiology (RUMC) & Pediatrics (SHCC)), Rush University Medical Center-Stroger Hospital of Cook County A/I Program, Chicago, IL, ³Radiology, Geisinger Medical Center, Danville, PA.

685   The Case of the Polysaccharide Blues

R. Gupta, H. J. Wedner; Internal Medicine, Barnes Jewish Hospital, St. Louis, MO.

Oral Abstract Session

3601

Sunday, March 05, 2006

2:00 pm to 3:15 pm

Inflammation

686   Efficacy of Airway Anti-Inflammatory Treatments Evaluated with Airway Inflammation Markers in Patients with Cough Variant Asthma: Budesonide versus Montelukast

T. T. Shimoda, R. R. Kishikawa, S. S. Shoji, S. S. Nishima; Clinical Research Center, Fukuoka National Hospital, Fukuoka, JAPAN.

687   Urine LTE4 Levels and Lung Function Declines are Highly Correlated in Urban Children with Moderate to Severe Asthma Despite Use of Inhaled Corticosteroids and Long-acting Bronchodilators

N. Rabinovitch; Pediatrics, National Jewish Medical and Research Center, Denver, CO.

688   Relationship between Exhaled Nitric Oxide and Methacholine Bronchial Provocative Test in Asthmatic Children

C. Direkwattanachai ¹, W. Teawsomboonkit¹, C. Sasisakulporn²; ¹Division of Allergy/Immunology, Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND, ²Research Center, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND.

689   FENO 35ppb - Is it Associated with Asthma Control

C. Lopes; Hospital S. João, Porto, PORTUGAL.

Oral Abstract Session

3602

Sunday, March 05, 2006

2:00 pm to 3:15 pm

Skewing of the Adaptive Immune Response to Allergens

690   Differential Expression of NF-kB Molecular Species in Th1 and Th2 Cells

R. J. Kurnat, U. De Fanis, W. Lee, S. N. Georas, J. Guo, V. Casolaro; Johns Hopkins University, Baltimore, MD.

691   Immunomodulation of T Cells by Targeting Allergen to Antigen Presenting Cells

K. Hulse ¹, A. J. Reefer¹, S. M. Satinover¹, M. D. Chapman², V. Engelhard¹, J. A. Woodfolk¹; ¹University of Virginia, Charlottesville, VA, ²Indoor Biotechnologies, Charlottesville, VA.

692   CD4 T Cells Receive Costimulatory Signals from CpG DNA during Antigen-Specific Stimulation

D. F. LaRosa, A. E. Gelman, L. A. Turka; University of Pennsylvania, Philadelphia, PA.

693   Therapeutic Use of The Co-Administration of Immunostimulatory DNA Sequence with Allergen Extract in a Mouse Model of Timothy Allergy

J. W. Kim, J. Lee, S. Lee, T. Yoo; Allery/Immunology, University of Tennessee, Memphis, TN.

Oral Abstract Session

3603

Sunday, March 05, 2006

2:00 pm to 3:15 pm

Environmental Determinants in Allergic Disease: What are Cohort Studies Telling Us?

694   Association of Mouse, Cockroach and Dustmite IgE Levels at Age 2 with Traffic-Related Air Pollution Exposure and Respiratory Symptoms in an Inner City Birth Cohort

U. Al-alem ¹, C. Lendor¹, J. Kong¹, R. Garfinkel², G. Chew², M. Perzanowski², D. Camann³, R. M. Whyatt², P. L. Kinney², F. Perera², R. L. Miller¹; ¹Department of Medicine, Division of Pulmonary, Allergy, Critical Care Medicine, Columbia University College of Physicians and Surgeons, New York, NY, ²Columbia Center for Children's Environmental Health (CCCEH), Mailman School of Public Health, Columbia University, New York, NY, ³Department of Analytical and Environmental Chemistry, Southwest Research Institute, San Antonio, TX.

695   Risk Factors for the Persistent Expression of Atopic Dermatitis in a High-Risk Birth Cohort

A. Singh ¹, R. Gangnon², M. Evans², K. Roberg³, C. Tisler³, D. DaSilva³, T. Pappas³, L. Pleiss³, J. E. Gern³, R. F. Lemanske, Jr.⁴; ¹Medicine, University of Wisconsin-Madison, Madison, WI, ²Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, ³Pediatrics, University of Wisconsin-Madison, Madison, WI, ⁴Pediatrics and Medicine, University of Wisconsin-Madison, Madison, WI.

696   Exposure to Allergens and Endotoxin in Early Life and Recurrent Wheezing in Infants: a Cohort Study

V. E. Rullo¹, D. Solé¹, L. Arruda ², V. Valente¹, C. Nakamura¹, A. S. Zampolo², L. R. Roberti³, F. J. Nóbrega⁴, C. K. Naspitz¹; ¹Pediatrics, Federal University of São Paulo, São Paulo, BRAZIL, ²Medicine, School of Medicine of Ribeirão Preto-University of São Paulo, Ribeirão Preto, BRAZIL, ³Pediatrics, School of Medicine of Ribeirão Preto-University of São Paulo, Ribeirão Preto, BRAZIL, ⁴Pediatrics, Albert Einstein Hospital, São Paulo, BRAZIL.

697   Symptoms at Age One as Predictors of Aeroallergen Sensitization During Infancy: The Cincinnati Childhood Allergy and Air Pollution Study (CCAAPS)

G. K. LeMasters ¹, J. E. Lockey¹, P. H. Ryan¹, L. Levin¹, G. Hershey², M. Villareal³, D. I. Bernstein³; ¹Environmental Health, University of Cincinnati, Cincinnati, OH, ²Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Internal Medicine, Division of Immunology, University of Cincinnati, Cincinnati, OH.

Oral Abstract Session

3604

Sunday, March 05, 2006

2:00 pm to 3:15 pm

Angioedema

698   Treatment with Pasteurized C1 Inhibitor Concentrate in Abdominal Pain Attacks of Patients with Hereditary Angioedema

P. Staubach, G. Meng, K. Bork; Department of Dermatology, Mainz, GERMANY.

699   Interim Results of EDEMA2, a Multicenter, Open-label, Repeat-Dosing Study of Intravenous and Subcutaneous Administration of Ecallantide (DX-88) in Hereditary Angioedema

W. Lumry ¹, B. Ritchie², T. Beck³, J. Morrison³; ¹Allergy & Asthma Specialists, Dallas, TX, ²University of Alberta, Edmonton, AB, CANADA, ³Dyax Corp., Cambridge, MA.

700   Home Treatment in Patients with Hereditary Angiodema (HAE)

E. Rusicke, I. Martinez-Saguer, E. Aygören-Pürsün, W. Kreuz; Centre of Pediatrics III Department of Hematology, Hemostaseologie, Oncology and Immunodeficiency, JWG-University Hospital Frankfurt/Germany, Frankfurt/Main, GERMANY.

701   Individual Replacement Therapy (IRT) with a Pasteurized C1-Inhibitor Concentrate Compared to Prophylaxis with Danazol in Patients with Hereditary Angioedema (HAE) - A Prospective Study

I. Martinez-Saguer, E. Rusicke, E. Aygören-Pürsün, W. Kreuz; Centre of Pediatrics III, Department of Hematology, Hemostaseology, Oncology and Immunodeficiency, J.-W. Goethe University Hospital Frankfurt, Germany, Frankfurt, GERMANY.

Oral Abstract Session

3605

Sunday, March 05, 2006 2:00 pm to 3:15 pm

Asthma Care Delivery

702   Using Geographic Information System (GIS) Software to Examine US Adult Asthma Prevalence and Healthcare Services Disparities

H. J. Zeitz ¹, M. N. Lutfiyya², J. E. McCullough³, E. Henley²; ¹National Center for Rural Health Professions, University of Illinois, Rockford, IL, ²Family and Community Medicine, University of Illinois, Rockford, IL, ³Chicago Department of Public Health, Chicago, IL.

703   Life Stressors, Depression and Adult Asthma Morbidity

M. U. Shalowitz ¹, J. J. Shannon², K. Weiss³; ¹Pediatrics, Northwestern University Feinberg School of Medicine, Evanston, IL, ²Internal Medicine, John H. Stroger Hospital of Cook County, Chicago, IL, ³Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.

704   Reduced Prevalence of Childhood Wheeze in Children Given Neonatal BCG Vaccination

M. F. Linehan ¹, T. L. Frank¹, M. L. Hazell¹, H. C. Francis², D. N. Baxter³, J. Morris⁴, R. M. Niven²; ¹GP Research Unit, North West Lung Research Centre, Manchester, UNITED KINGDOM, ²North West Lung Research Centre, Manchester, UNITED KINGDOM, ³School of Epidemiology and Health Science, University of Manchester, Manchester, UNITED KINGDOM, ⁴Department of Statistics, Wythenshawe Hospital, Manchester, UNITED KINGDOM.

705   Assessing Productivity Impairment in Patients with Severe or Difficult-to-Treat Asthma: Validation of the Work Productivity Activity Impairment - Asthma Questionnaire

H. Chen ^1,2, P. D. Blanc¹, A. Chawla², M. Hayden³, E. R. Bleecker⁴, J. H. Lee²; ¹Department of Medicine, UCSF, San Francisco, CA, ²Genentech, Inc., South San Francisco, CA, ³School of Nursing, University of Virginia, Charlottesville, VA, ⁴Wake Forest University, Winston-Salem, NC.

Oral Abstract Session

3606

Sunday, March 05, 2006

2:00 pm to 3:15 pm

Allergic Disease Pathogenesis

706   Osteopontin: A Novel Regulator in Antigen-Induced IgE and Allergic Responses

M. Kurokawa, Q. Liu, S. Konno, S. C. Hsu, B. Plunkett, H. Rohde, S. Y. Oh, T. Zheng, Z. Zhu, A. C. Myers, S. K. Huang; Johns Hopkins Asthma and Allergy Center, Baltimore, MD.

707   Ribonomic Analysis of Airway Epithelial Cell Gene Expression: Identification of Chemokine Transcripts as Targets of the RNA-Binding Protein HuR

C. Stellato ¹, S. L. Curry¹, U. X. Atasoy², M. Gorospe³, J. Fan¹; ¹Division of Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD, ²University of Missouri-Columbia, Columbia, MO, ³National Institute of Aging, NIH, Baltimore, MD.

708   Lipocalin2 (lcn2) is Upregulated and May Serve as a Novel Protective Factor in Allergic Airway Disease

A. M. Dittrich, D. Quarcoo, M. Krokowski, A. Awagjan, B. Ahrens, E. H. Hamelmann; Pediatric Pneumology and Immunology, Charité University Medicine, Berlin, GERMANY.

709   Role of Resistin-Like Molecule (RELM)-b in Allergic Airway Inflammation

A. Haczku ¹, S. Ying², S. Kierstein¹, Q. Meng², L. D. McVay¹, C. J. Corrigan², G. D. Wu¹; ¹Medicine, University of PA School of Medicine, Philadelphia, PA, ²Guy's, King's & St. Thomas’ School of Medicine, London, UNITED KINGDOM.

Oral Abstract Session

3607

Sunday, March 05, 2006 2:00 pm to 3:15 pm

Rhinosinusitis

710   Aspirine Sensitive Rhinosinusitis is Associated with Reduced E-prostanoid 2(EP2) Receptor Expression on Nasal Mucosal Inflammatory Cells

S. Ying ¹, Q. Meng¹, G. Scadding², A. Parikh², C. J. Corrigan¹, T. H. Lee¹; ¹Asthma, Allergy & Respiratory Science, GKS Medical School, London, UNITED KINGDOM, ²Royal National Throat, Nose and Ear Hospital, London, UNITED KINGDOM.

711   Enhanced Expression of Innate Immune Genes in Chronic Rhinosinusitis

A. Q. Truong-Tran ¹, R. Kern², D. Conley², S. Retsema², L. Grammer, III¹, L. Suh¹, J. Tirumalasetty¹, B. Tancowny¹, A. Tripathi¹, R. Schleimer¹; ¹Allergy-Immunology, Northwestern University, Chicago, IL, ²Otolaryngology, Northwestern University, Chicago, IL.

712   Total and Specific Nasal IgE to Dermatophagoides Pteronyssinus in Patients with Persistent Rhinitis

C. Rondon1, S. Lopez2, R. R-Pena2, J. J. Romero1, T. D. Fernandez2, C. Antunez2, I. Dona1, M. S. Fuentes1, J. L. Rodriguez-Bada2, M. Blanca1; 1Allergy Service, Carlos Haya Hospital, Malaga, SPAIN, 2Research Laboratory, Carlos Haya Hospital, Malaga, SPAIN.

713   A Genomewide Screen for Chronic Rhinosinusitis Genes Identifies a Locus on Chromosome 7q

J. M. Pinto ¹, M. G. Hayes², D. Schneider³, N. Phillips⁴, J. Hyuen⁴, N. J. Cox², R. M. Naclerio¹, C. Ober⁴; ¹Section of Otolaryngology-Head and Neck Surgery, The University of Chicago, Chicago, IL, ²Section of Genetic Medicine, Department of Medicine and Department of Human Genetics, The University of Chicago, Chicago, IL, ³Departmenr of Human Genetics, The University of Chicago, Chicago, IL, ⁴Department of Human Genetics, The University of Chicago, Chicago, IL.

Featured Poster Session

3801

Sunday, March 05, 2006

5:30 pm to 7:30 pm

Featured Poster Session

714   Ciclesonide, Administered Once Daily, has No Effect on Skeletal Maturity in Prepubertal Children with Mild, Persistent Asthma

H. Neffen ¹, M. Ruff², P. Zhang³, M. Lloyd³, D. Banerji³; ¹Centro de Alergia e Inmunologia, Santa Fe, ARGENTINA, ²Dallas Allergy & Asthma Center, Dallas, TX, ³Aventis Pharmaceuticals, a member of the sanofi-aventis Group, Bridgewater, NJ.

715   Once-daily Ciclesonide has No Effect on Hypothalamic-Pituitary-Adrenal-axis Function in Prepubertal Children with Mild, Persistent Asthma

D. Bernstein ¹, F. Caballero-Fonseca², P. Zhang³, M. Lloyd³, D. Banerji³; ¹Bernstein Clinical Research, Cincinnati, OH, ²Centro Medico Docente La Trinidad, Caracas, VENEZUELA, ³Aventis Pharmaceuticals, a member of the sanofi-aventis Group, Bridgewater, NJ.

716   Quality of Life is Improved by Ciclesonide 160 μg Once Daily and Budesonide 400 μg Once Daily in Pediatric Patients with Persistent Asthma

J. H. Vermeulen ¹, T. Latos², T. Müller³, R. Engelstätter³; ¹Parow, Cape Town, SOUTH AFRICA, ²Centrum Pulmonologii i Alergologii, Karpacz, POLAND, ³ALTANA Pharma AG, Konstanz, GERMANY.

Featured Poster Session

3802

Sunday, March 05, 2006

5:30 pm to 7:30 pm

Gene-Environment Interactions in Allergic Diseases

717   Gene-Environment Interaction between CD14 -159C→T and Diesel Exhaust Particle (DEP) Exposure Underlying Aero Allergen Sensitization

N. Wang ¹, N. Huey¹, S. Sutton¹, M. Rao², R. Chakraborty², G. LeMasters², D. Bernstein², T. Reponen², J. Lockey², S. Grinshpun², G. K. K. Hershey¹; ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²University of Cincinnati, Cincinnati, OH.

718   Gene-environment Interactions with CD14: Sorting Out The Effects of Pets and Endotoxin on Serum IgE Levels

L. K. Williams¹, R. A. McPhee¹, E. L. Peterson¹, D. R. Ownby², M. James¹, E. M. Zoratti¹, C. C. Johnson¹; ¹Henry Ford Health System, Detroit, MI, ²Medical College of Georgia, Augusta, GA.

719   Single Nucleotide Polymorphisms in Gene Encoding Myosin Light Chain Kinase (MLCK) are Associated with Increased Risk of Asthma

L. GAO ¹, A. Ilano², A. Grant¹, M. Campbell¹, S. Zhang¹, T. H. Beaty³, J. G. N. Garcia⁴, K. Barnes¹; ¹Division of Allergy & Clinical Immunology, Johns Hopkins University, Baltimore, MD, ²Seton Hall University, South Orange, NJ, ³Department of Epidemiology, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD, ⁴Department of Medicine, The University of Chicago Biological Sciences, Chicago, IL.

Featured Poster Session

3803

Sunday, March 05, 2006

5:30 pm to 7:30 pm

Featured Poster Session

720   Home Environment Related to Respiratory and Allergic Diseases in Children Taking Into Account Early Exposure

C. Pénard-Morand ¹, C. Raherison², D. Moreau¹, C. Kopferschmitt³, F. Lavaud⁴, D. Caillaud⁵, D. Charpin⁶, I. Annesi-Maesano¹; ¹U472, INSERM, Villejuif, FRANCE, ²Hôpital du Haut-Lévèque, Bordeaux, FRANCE, ³Hôpitaux Civils, Strasbourg, FRANCE, ⁴Hôpital Maison Blanche, Reims, FRANCE, ⁵Hôpital Montpied, Clermont-Ferrand, FRANCE, ⁶Hôpital Nord, Marseille, FRANCE.

721   Time-dependent Effects of Dog Exposure and Genotype at Immune-Related Genes on Wheezing and Atopy in Early Childhood

J. Bufford ¹, Z. Li², C. Reardon³, K. A. Roberg³, C. Tisler³, E. Anderson³, D. DaSilva³, I. Ostrovnaja⁴, S. Hoffjan⁵, D. Nicolae⁴, R. Gangnon², C. Ober⁵, R. F. Lemanske, Jr.⁶, J. E. Gern³; ¹Medicine, University of Wisconsin-Madison, Madison, WI, ²Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, ³Pediatrics, University of Wisconsin-Madison, Madison, WI, ⁴Department of Statistics, University of Chicago, Chicago, IL, ⁵Department of Human Genetics, University of Chicago, Chicago, IL, ⁶Pediatrics and Medicine, University of Wisconsin-Madison, Madison, WI.

722   Combined Effects of the Glutathione S-transferase P1 (GST-P1) Gene Polymorphism and Environmental Tobacco Smoke (ETS) Exposure on the Development of Asthma

K. T. Shair ¹, J. M. Biagini², G. K. LeMasters², D. I. Bernstein³, J. E. Lockey², G. K. Khurana Hershey¹; ¹Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Environmental Health, University of Cincinnati, Cincinnati, OH, ³Internal Medicine, University of Cincinnati, Cincinnati, OH.

Featured Poster Session

3804

Sunday, March 05, 2006

5:30 pm to 7:30 pm

Featured Poster Session

723   Deficient HBD-3 in the Skin of Atopic Dermatitis (AD) Patients Increases Susceptibility to Recurrent Viral Skin Infections

M. D. Howell ¹, J. E. Streib¹, N. Novak², T. Bieber², M. Boguniewicz¹, S. Pastore³, G. Girolomoni³, D. Y. M. Leung¹; ¹National Jewish Med. and Research Center, Denver, CO, ²University of Bonn, Bonn, GERMANY, ³Instituto Dermopatico dell'Immacolata, Roma, ITALY.

724   A Role for Circulating Pro-Inflammatory CD25^hiCCR6⁺CD4⁺ T Cells in Atopic Dermatitis

A. J. Reefer¹, S. M. Satinover¹, M. Solga², B. Wilson³, J. A. Woodfolk ¹; ¹Department of Medicine, University of Virginia, Charlottesville, VA, ²Department of Microbiology, University of Virginia, Charlottesville, VA, ³Department of Dermatology, University of Virginia, Charlottesville, VA.

725   Atopic Dermatitis (AD) and Eczema Herpeticum (EH): Role of Cathelicidins in Herpes Simplex Virus (HSV) Infection

D. Y. M. Leung ¹, A. Wollenberg², R. L. Gallo³, M. Flaig², N. Novak⁴, T. Bieber⁴, M. Boguniewicz¹, J. E. Streib¹, C. Wong³, T. Pavicic², M. D. Howell¹; ¹National Jewish Medical and Research Center, Denver, CO, ²Ludwig Maximilian's University, Munich, GERMANY, ³University of California at San Diego, San Diego, CA, ⁴University of Bonn, Bonn, GERMANY.

Featured Poster Session

3805

Sunday, March 05, 2006

5:30 pm to 7:30 pm

Featured Poster Session

726   Impact of Atopic Dermatitis on Quality of Life and Patient Attitudes Towards Current Management Options

T. Zuberbier; Dept. of Dermatology and Allergy, Charité - Universitätsmedizin Berlin, Berlin, GERMANY.

727   A Cost-Effectiveness Analysis of Aspirin Desensitization in Aspirin Sensitive Patients

M. S. Shaker, M. E. Goodrich, A. L. Lobb, F. Jaffrey, M. S. Verdi; Section of Allergy and Clinical Immunology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

728   Improving the Safety of Immunotherapy: A Systematic Approach

T. Bingemann, C. Oslie, W. Molis, J. T. Li; Mayo Clinic and Foundation, Rochester, MN.

Featured Poster Session

3806

Sunday, March 05, 2006

5:30 pm to 7:30 pm

Featured Poster Session

729   Airway Expression of Calcitonin Gene-Related Peptide in T-Cell Peptide-Induced Late Asthmatic Reactions

F. R. Ali ¹, L. G. Heaney², F. Benyahia¹, J. Barkans¹, C. P. Soh³, A. Mochizuki⁴, A. F. Walls⁴, A. Humbles⁵, H. Renz⁶, S. Ying³, T. Lee³, M. Larché¹, A. B. Kay¹; ¹Dept. of Allergy and Clinical Immunology, and Leukocyte Biology, National Heart & Lung Institute, Imperial College, London, UNITED KINGDOM, ²Queen's University, Belfast, UNITED KINGDOM, ³GKT School of Medicine, Guy's campus, London, UNITED KINGDOM, ⁴Immunopharmacology, University of Southampton, Southampton, UNITED KINGDOM, ⁵Ina Sue Perlmutter Laboratory, Children's Hospital, Harvard Medical School, Boston, MA, ⁶Department of Clinical Chemistry and Molecular Diagnostics, Philipps-University Marburg, Marburg, GERMANY.

730   Innate Immune Response to an Environmental Fungus, Alternaria, Facilitates Th2-Type Airway Sensitization to a Bystander Antigen

T. Kobayashi ¹, K. Iijima¹, S. Radhakrishnan², V. Mehta¹, R. Vassallo³, L. R. Pease², H. Kita¹; ¹Division of Allergic Diseases, Department of Internal Medicine, Mayo Clinic Rochester, Rochester, MN, ²Department of Immunology, Mayo Clinic Rochester, Rochester, MN, ³Division of Pulmonary and Critical Care and Internal Medicine, Mayo Clinic Rochester, Rochester, MN.

731   Human Peripheral Blood Eosinophils Express Functional Glutamate Receptors

S. O. Odemuyiwa ¹, V. Lam¹, M. Benn¹, A. Ghahary¹, M. Duszyk², R. Moqbel¹; ¹Department of Medicine, Pulmonary Research Group, University of Alberta, Edmonton, AB, CANADA, ²Department of Physiology, Pulmonary Research Group, University of Alberta, Edmonton, AB, CANADA.

732   Exogeneous Chitinases Activate and Induce Degranulation of Human Eosinophils through a Protease-Activated Receptor-2 (PAR-2)

Y. MATSUWAKI, W. Thomas, K. Hotta, H. Kita; Department of Allergic Research labo., Mayo Clinic Rochester, Rochester, MN.

Featured Poster Session

3807

Sunday, March 05, 2006

5:30 pm to 7:30 pm

Featured Poster Session

733   Allergy Skin Prick Testing, Self-Reported Hay Fever Diagnosis and Self-Reported Allergy Symptoms in the Third National Health and Nutrition Examination Survey (NHANES III)

L. Watson ¹, D. W. Clark², K. J. Davis², M. A. Corrao²; ¹Worldwide Epidemiology, GlaxoSmithKline, Greenford, UNITED KINGDOM, ²Worldwide Epidemiology, GlaxoSmithKline, Research Triangle Park, NC.

734   Comparison of Two Single-Headed and Two Multiheaded Prick Skin Test Devices

I. Yoon ¹, B. L. Martin¹, W. W. Carr²; ¹Allergy-Immunology, Walter Reed Army Medical Center, Washington, DC, ²Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD.

735   Testing a Direct, Highly Sensitivity Method for Quantitation of Fluticasone Propionate in Human Plasma: Contrasting Nasal and Inhaled Exposure

P. Patel¹, P. Benninger¹, A. Cooper¹, R. Moisan¹, J. J. Thiessen ²; ¹Allied Research International, Mississauga, ON, CANADA, ²Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, CANADA.

Poster Session

4201

Monday, March 06, 2006 9:45 am to 10:45 am

Pharmacokinetics, Genetics, and Pathogenesis

736   The Effect of Dexamethasone on TGF-ß-Induced Hyperplasia of Bronchial Smooth Muscle Cells

T. Basinski¹, K. Blaser², C. Akdis², M. Jutel ¹; ¹Department of Internal Medicine and Allergology, Wroclaw Medical University, Wroclaw, POLAND, ²Swiss Institute of Allergy and Asthma Research (SIAF), Davos, SWITZERLAND.

737   Once-daily Ciclesonide has No Effect on Growth in Children with Mild, Persistent Asthma: a Subgroup Analysis of North and South American Populations

C. E. Baena-Cagnani ¹, L. Mansfield², P. Zhang³, M. Lloyd³, D. Banerji³; ¹University of Cordoba, Cordoba, ARGENTINA, ²El Paso Institute for Medical Research and Development, El Paso, TX, ³Aventis Pharmaceuticals, a member of the sanofi-aventis Group, Bridgewater, NJ.

738   Ciclesonide has No Effect on Growth in Prepubertal Children with Mild, Persistent Asthma, Irrespective of Age and Gender

A. Nayak ¹, O. Herrera², S. Kundu³, M. Lloyd³, D. Banerji³; ¹Sneeze, Wheeze, and Itch Associates, LLC, Normal, IL, ²Hospital Luis Calvo Mackena, Providencia-Santiago, CHILE, ³Aventis Pharmaceuticals, a member of the sanofi-aventis Group, Bridgewater, NJ.

739   The Effect of Budesonide on IgE and IgG Subclasses in Asthmatic Children

M. Bobrowska-Korzeniowska, J. Jerzynska, I. Stelmach; Department of Pediatrics and Allergy, Medical University of Lodz, M Curie Hospital, Zgierz, POLAND.

740   Tissue Distribution of Ciclesonide and Budesonide in Mice

U. Mars ¹, A. Johansson¹, E. Evetovics², P. Sjolin², A. Miller-Larsson², S. Edsbacker²; ¹Safety Assessment, AstraZeneca R&D, Sodertalje, SWEDEN, ²AstraZeneca R&D, Lund, SWEDEN.

741   Asthma Control and Exhaled Nitric Oxide in Real Life

A. Michils, A. Van Muylem; Chest Department, Erasme University Hospital, Brussels, BELGIUM.

742   Never-Smoking Senile-Onset Asthmatics Show Atypical and Mild Asthma Symptoms

C. Oshikata, M. Taniguchi, Y. Takeuchi, E. Ono, T. Tsuburai, N. Tsurikisawa, M. Ohtomo, Y. Maeda, A. Mori, M. Hasegawa, H. Mita, K. Akiyama; Asthma reseach devision, National Sagamihara Hospital, Sagamihara, JAPAN.

743   Effect of Feedback Education of a Respiratory Service Program(RSP) on Inhaler

J. CHUNG, K. SHIN, K. LEE; Department of internal medicine, YEUNGNAM UNIVERSITY HOSPITAL, DAEGU, REPUBLIC OF KOREA.

744   Fungi Play an Important Role in Bronchial Asthma

T. Hofman, A. M. Hofman, A. Urbanowicz, J. Michalik; Center of Allergology, Poznan, POLAND.

745   Measurement of Exhaled Breath Temperature to Assess Changes in Airway Inflammation

T. Popov ¹, S. Dunev¹, T. Kralimarkova¹, L. M. DuBuske²; ¹Medical University of Sofia, Sofia, BULGARIA, ²Immunology Research Institute of New England, Gardner, MA.

746   The Role of Histamine Challenge and Progressive Exercise Testing in the Diagnosis of Vocal Cord Dysfunction

A. E. Stanton ¹, K. MacKenzie², R. Carter¹, C. E. Bucknall¹; ¹Department of Respiratory Medicine, Glasgow Royal Infirmary, Glasgow, UNITED KINGDOM, ²Department of Otolaryngology, Glasgow Royal Infirmary, Glasgow, UNITED KINGDOM.

747   Cytokines Epistasis Contributes to Childhood Asthma

I. R. Genov ¹, A. Goncalves-Primo, Jr.¹, A. Yambartsev², L. K. Arruda³, A. S. Zampolo³, V. P. L. Ferriani⁴, D. Solé¹, C. K. Naspitz¹, M. Gerbase-DeLima¹, A. Morgun¹; ¹Department of Pediatrics, Federal University of Sao Paulo, Sao Paulo, BRAZIL, ²Mathematics and Statistics Institute, University of Sao Paulo, Sao Paulo, BRAZIL, ³Department of Medicine, University of Sao Paulo, Ribeirao Preto, BRAZIL, ⁴Department of Pediatrics, University of Sao Paulo, Ribeirao Preto, BRAZIL.

748   Asthma Biomarkers in Exhaled Breath Condensate (EBC)

S. L. Limb ¹, W. C. Hubbard², R. A. Wood³, N. Adkinson, Jr.⁴; ¹Johns Hopkins School of Medicine, Baltimore, MD, ²Clinical Pharmacology, Johns Hopkins School of Medicine, Baltimore, MD, ³Pediatric Allergy and Immunology, Johns Hopkins School of Medicine, Baltimore, MD, ⁴Allergy and Clinical Immunology, Johns Hopkins School of Medicine, Baltimore, MD.

749   Corticosteroid Resistant (CR) Asthma Is Associated with Classical Activation Of Airway Macrophages and Exposure To Lipopolysaccharide (LPS)

P. J. Hauk ¹, E. Goleva¹, A. H. Liu¹, C. F. Hall¹, D. W. H. Riches¹, R. J. Martin², D. Y. M. Leung¹; ¹Pediatrics, National Jewish Medical and Research Center, Denver, CO, ²Medicine, National Jewish Medical and Research Center, Denver, CO.

750   History of Smoking is Strongly Correlated with Decreased Exhaled Nitric Oxide, Eosinophils, and Serum Ecp in White but not African American Patients

E. Peters¹, J. Platts-Mills ², L. Naccara², S. Crater³, S. Lucas², T. A. E. Platts-Mills²; ¹Allergy, Seton Hospital, Austin, TX, ²Allergy, University of Virginia, Charlottesville, VA, ³Dermatology, Charleston, SC.

751   Atopy and House Dust Mite Sensitization as Risk Factors for Asthma in Children

S. Jung Wook ¹, K. Eun Soo¹, K. Kyung Won¹, J. Gwang Cheon², S. Myung Hyun¹, K. Kyu-Earn¹, J. Y. Park¹; ¹Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, NHIC Ilsan Hospital, seoul, REPUBLIC OF KOREA.

752   Phenotypic Assessment of a Functional Sequence Variant of the Gene Encoding Human Chemoattractant Receptor-homologous Molecule Expressed on Th₂ Cells (crth2)

C. F. CHIAN, P. S. Gao, U. D. Fanis, V. Casolaro, N. F. Adkinson, Jr., S. K. Huang; Allergy and clinical immunology, JOHNS HOPKINS UNIVERSITY, BALITIMORE, MD.

753   Characteristics of Japanese Cedar/Cypress Pollen in 2005, Fukuoka, Japan

R. Kishikawa, T. Shimoda, S. Shoji, S. Nishima, Sr.; Allergology, The National Hospital Organization Fukuoka National Hospital Clinical Reserch Center, Fukuoka, JAPAN.

754   The Performance of a New Component-Based Allergen-Microarray in Clinical Practice

S. Wöhrl ¹, K. Vigl¹, S. Zehetmayer², R. Hiller³, R. Jarisch⁴, M. Prinz⁵, G. Stingl¹, T. Kopp¹; ¹Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna, Vienna, AUSTRIA, ²Core unit for Medical Statistics and Informatics, Section on Medical Statistics, Medical University of Vienna, Vienna, AUSTRIA, ³VBC-Genomics, Vienna, AUSTRIA, ⁴Floridsdorf Allergy Centre (FAZ), Vienna, AUSTRIA, ⁵Core unit for Medical Statistics and Informatics, Section on Medical Computer Vision, Medical University of Vienna, Vienna, AUSTRIA.

Poster Session

4202

Monday, March 06, 2006 9:45 am to 10:45 am

Pharmacokinetics, Genetics, Epidemiology and Pathogenesis

755   Safety of Foradil^® in the Treatment of Asthma: A Pooled Analysis of Randomized, Controlled Clinical Trials

G. P. Geba ¹, B. Ziehmer², H. Staudinger³, D. Till⁴; ¹USCDMA, Novartis Pharmaceuticals Corp., E Hanover, NJ, ²Global Development, Novartis Pharmaceuticals Corp., E Hanover, NJ, ³Schering-Plough Corporation, Kenilworth, NJ, ⁴Novartis Horsham Research Centre, Novartis Pharmaceuticals Corp., Horsham, UNITED KINGDOM.

756   Safety of High-Dose Continuous Nebulized Levalbuterol

T. Andrews ¹, E. E. McGintee², L. Tyler³, M. Mittal⁴, N. A. Pawlowski², J. Zorc⁴; ¹Allergy and Asthma Associates, Arnold, MD, ²Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, PA, ³Respiratory Care, Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Emergency Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.

757   Safety of Ventolin HFA^® MDI in Children Birth-<24 Months Old With Symptoms of Bronchospasm

A. Davis-Allen, W. Lincourt, R. Trivedi, A. Ellsworth, C. Crim; GlaxoSmithKline, Research Triangle Park, NC.

758   Indacaterol, A Novel Once-Daily b₂-Agonist, Demonstrates 24-hour Efficacy and is Well Tolerated in Patients with Persistent Asthma

F. Kanniess ¹, R. Cameron², R. Owen², M. Higgins²; ¹Pulmonary Research Institute, Grosshansdorf, GERMANY, ²Novartis Horsham Research Centre, Horsham, UNITED KINGDOM.

759   Formoterol Induces Higher Levels of Total cAMP in TNFa-Stimulated Human Monocytes than Salmeterol

I. Nita¹, A. Miller-Larsson², S. Janciauskiene ¹; ¹Clinical Sciences, Lund University, Malmö, SWEDEN, ²AstraZeneca R&D Lund, Lund, SWEDEN.

760   Normal Pulmonary Function in Alpha-1-Antitrypsin Deficiency ZZ Phenotype

M. L. Fajt ¹, J. Gibbs², L. H. Fisher³, T. J. Craig²; ¹Department of Medicine, Pennsylvania State University-Milton S. Hershey Medical Center, Hershey, PA, ²Department of Allergy-Immunology and Pulmonary Medicine, Pennsylvania State University-Milton S. Hershey Medical Center, Hershey, PA, ³Department of Allergy-Immunology, Pennsylvania State University-Milton S. Hershey Medical Center, Hershey, PA.

761   Asthma Hospitalizations in Children 2 Years Old or Less in New York State 1990-2004

T. J. Pitt ¹, R. Y. Lin^2,3; ¹St Vincent Hospital Manhattan-SVCMC, New York, NY, ²St Vincent Hospital Manhattan- SVCMC, New York, NY, ³New York Medical College, Valhalla, NY.

762   Correlation between Exhaled Nitric Oxide (eNO) and Symptoms, Medication Use and Quality of Life in Patients Diagnosed with Mild to Moderate Persistent Asthma

J. Kaczmarek, M. Bochen´ska-Marciniak, M. Kupczyk, P. Górski, P. Kuna; Department of Pneumonology and Allergy, Medical University of Lodz, Lodz, POLAND.

763   Sex Differences in Effects of Breastfeeding on Asthma and Allergy in Relation to Parental Atopy

P. J. Mandhane, J. M. Greene, M. R. Sears; McMaster University, Hamilton, ON, CANADA.

764   The Follow of Changes in Inflammatory Markers in Induced Sputum of Patients with Bronchial Asthma and Allergic Rhinitis in Relation to Exposure to Pollen Allergens

V. Hrasko, I. Malkusova, J. Hanzlikova, P. Panzner; Medical Faculty Hospital, Plzen, CZECH REPUBLIC.

765   Association between Peroxiredoxin (PRDX) VI Gene Polymorphism and Asthma and Its Intermediate Phenotypes

T. B. Kim, Y. S. Cho, C. S. Park, K. Y. Lee, H. B. Moon; Department of Medicine, Clinical Research Center for Chronic Obstructive Airway Disease, Asan Medical Center, University of Ulsan College of Medicine, Seoul, REPUBLIC OF KOREA.

766   Gene-Gene Interaction Between CD14 and IL-4Ra polymorphisms Is Associated with Asthma Susceptibility in Korean Children with Asthma

S. Lee ¹, H. Kim², J. Kim², B. Kim², M. Kang³, S. Hong²; ¹Department of Pediatrics, University of Hallym College of Medicine, Seoul, REPUBLIC OF KOREA, ²Department of Pediatrics, Asan Medical Center, Seoul, REPUBLIC OF KOREA, ³Asan Institute for Life Sciences, Seoul, REPUBLIC OF KOREA.

767   Changes in Specific Ige Sensitization Rates in Children 1985-2003: Review of 9,365 Allergy Tests Performed in a Single Hospital Laboratory over a 19-Yr Period

P. L. P. Brand ¹, L. D. Dikkeschei²; ¹Princess Amalia Children's Clinic, Isala klinieken, Zwolle, THE NETHERLANDS, ²Clinical Laboratory, Isala klinieken, Zwolle, THE NETHERLANDS.

768   Accuracy of FDA-Cleared IgE Assays in the Presence of Omalizumab (Xolair)

R. G. Hamilton; Allergy and Clinical Immunology, Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.

769   Nafamostat Mesilate (FUT) and Gabexate Mesilate (FOY) Attenuates Allergic Airway Inflammation and Eosinophilia in Dermatophagoides pteronyssinus - Sensitized Mice

C. Chen; Division of Biomaterials and Tissue Engineering, BMEC, Industrial technology research institute, Hsinchu, TAIWAN REPUBLIC OF CHINA.

770   Total IgE Level is Associated with Anti-Ascaris Specific IgE but not with Stool Parasites or Blood Eosinophilia in Young Allergic Patients in a Tropical Region (Recife - Brazil)

D. Medeiros, A. R. Silva, J. A. Rizzo, M. E. Motta, E. Sarinho; Universidade Federal de Pernambuco, Recife, BRAZIL.

771   Concentrations of 15-HETE and PGE₂ in Induced Sputum of Allergic Asthma Patients

K. Kowal ¹, S. Zukowski¹, O. Kowal-Bielecka¹, L. M. DuBuske², A. Bodzenta-Lukaszyk¹; ¹Medical University of Bialystok, Bialystok, POLAND, ²Immunology Research Institute of New England, Gardner, MA.

772   Polymorphisms in the Cholinergic Receptor, Muscarinic 1 (CHRM1) Gene Confer Susceptibility to Asthma in Japanese

Y. Maeda, N. Hizawa, E. Jinushi, D. Takahashi, Y. Fukui, S. Konno, E. Yamaguchi, M. Nishimura; First department of Medicine, Hokkaido University school of Medicine, Sapporo, JAPAN.

773   Genetic Impacts of a Butyrophilin-like 2 (BTNL2) Gene Variation On Specific Ige Responsiveness to Dermatophagoides Farinae (Der F) in Japanese

D. Takahashi, N. Hizawa, S. Konno, A. Isada, A. Takahashi, T. Hattori, Y. Maeda, M. Nishimura; First Department of Medicine, Hokkaido University Graduate School of Medicine, Sapporo, JAPAN.

Poster Session

4203

Monday, March 06, 2006 9:45 am to 10:45 am

Immunomodulation

774   Aspirin Exerts Opposite Regulation of CD154 and Cytokine Gene Expression in Human Th1 and Th2 Cells

F. Mori, U. De Fanis, R. J. Kurnat, W. Lee, V. Casolaro; Johns Hopkins University, Baltimore, MD.

775   Restoration of Immune Mediated Hearing Loss by Adoptive Cellular Gene Therapy

T. Yoo, B. Zhou, M. Kermany, C. Cai, Q. Cai, P. Kim, J. Kim; Allery/Immunology,Molecular Sciences, University of Tennessee, Memphis, TN.

776   Sarcoptes scabiei Suppresses Expression of Adhesion Molecules and IL-8 by Human Dermal Microvascular Endothelial Cells (HMVEC-D)

B. L. Elder, M. S. Morgan, L. G. Arlian; Wright State University, Dayton, OH.

777   Lipoteichoic Acid and Peptidoglycan Inhibit Fc Epsilon RI Expression by Mast Cells

M. Yoshioka, S. Iriguchi, N. Imajo, M. Akagi, N. Fukuishi; Department of Pharmacology, Tokushima Bunri University, Tokushima, JAPAN.

778   Immunological Abnormalities and Cutaneous Lesions in a Pediatric Patient with Crohn's Disease Treated by Infliximab

Y. Wang, R. L. Roberts; Pediatrics, UCLA, Los Angeles, CA.

779   Sophorolipids Decrease IgE Production in U266 Cells.

M. H. Bluth ¹, T. A. Smith-Norowitz², M. Hagler¹, R. Beckford¹, S. Chice³, V. Shah⁴, R. Gross⁴, M. Nowakowski³, R. Schulze¹, M. Zenilman¹; ¹Department of Surgery, SUNY Downstate Medical Center, Brooklyn, NY, ²Pediatrics, SUNY Downstate Medical Center, Brooklyn, NY, ³Pathology, Center for Allergy and Asthma Research, SUNY Downstate Medical Center, Brooklyn, NY, ⁴NSF Center for Biocatalysis and Bioprocessing of Macromolecules, Polytechnic University, Brooklyn, NY.

780   Immunomodulatory Effects of Yunzhi-Danshen on Nasopharyngeal Carcinoma Patients

Y. X. Bao ^1,2, C. K. Wong¹, P. W. Li¹, E. L. Wong³, A. T. Chan⁴, S. F. Leung⁴, P. C. Leung³, K. P. Fung³, Y. B. Yin², W. K. Lam¹; ¹Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, CHINA, ²Department of Laboratory Medicine, The Chongqing University of Medical Sciences, Chongqing, CHINA, ³Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, CHINA, ⁴Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong, CHINA.

781   Bacterial Components Enhance Mast Cell Phagocytosis through the Expression of Complement Receptor 3

N. Imajo, M. Yoshioka, A. Inukai, M. Akagi, N. Fukuishi; Pharmacology, Tokushima Bunri University, Tokushima city, JAPAN.

782   Neonatal Exposure to Intranasal LPS Induces Immunological Tolerance via the Maturation of Specific Dendritic Cell Subsets and Subsequent Activation of Regulatory T Cells

Y. Wang, C. McCusker; Montreal Children's Hospital Research Institute and Meakins-Christie Laboratories, McGill University, Montreal, PQ, CANADA.

783   Interleukin 10 Functional Domain, Induces Human Monocytes Differentiation To T Cell Inhibitory Dendritic Cells

F. Salazar-Onfray; Faculty of Medicine, University of Chile, Santiago, CHILE.

784   Intragastric Curcumin Downregulates Aspergillus Antigen Induced Th2 Response in a Murine Model of Allergic Aspergillosis

V. P. Kurup ^1,2, C. S. Barrios¹, B. D. Johnson³, J. N. Fink¹; ¹Pediatrics/Allergy-Immunology, Medical College of Wisconsin, Milwaukee, WI, ²Research Service, V A Medical Center, Milwaukee, WI, ³Pediatrics, Medical College of Wisconsin, Milwaukee, WI.

785   Modulation and Upregulation of IL-5 and Mastocytosis in Hepatosplenic Schistosomiasis with Asthma

E. E. Fouda, A. I. M. Ali, M. H. Hemida; Allergy and Immunology Center, Al-Azhar University, Cairo, EGYPT.

786   DNA Vaccine Restores Hearing Loss Induced by b-Tubulin in Guinea Pig

J. Zhang, B. Zhou, Q. Cai, P. Kim, T. Yoo; Department of Medicine, University of Tennessee, Memphis, TN.

787   Regulatory Effect on Specific Ige Response of Bifido Bacterium Bifidum(bgn4 Strain) in Murine Model of Peanut Allergy

S. Lee, N. Koo, S. Oh; Pediatrics, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA.

788   Histamine Induces Expression of Cycloxygenase-2 and Regulates the Production of Prostacyclin(PGI₂) and Thromboxane-A2(TXA₂) in Human Coronary Artery Endothelial Cells(HCAEC)

S. Essengue ¹, J. Talreja², D. J. Stechschulte³, K. N. Dileepan⁴; ¹Pediatrics, University of Kansas Medical Center, Kansas City, KS, ²Division of Allergy, Clinical Immunology and Rheumatology, Departement of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, ³Division of Allergy, Clinical Immunology and Rheumatology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, ⁴Division of Allergy, Clinical and Rheumatology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS.

789   Inhibition of Indoleamine 2,3-Dioxygenase does not Impede Oral Tolerance

C. C. Bowman, M. J. DeVito, D. G. Ross, M. J. K. Selgrade; NHEERL, USEPA, Research Triangle Park, NC.

790   Atopy as a Predictor of Favorable Response to Treatment with Interferon-Alpha in Patients with Chronic Hepatitis B

M. R. Pijak ¹, F. Gazdik², E. Jahnova²; ¹1 Department of Internal Medicine, University Hospital, Bratislava, SLOVAKIA, ²Slovak Medical University, Bratislava, SLOVAKIA.

791   Macrophage Activation Syndrome after Hematopoietic Cell Transplantation

A. Sreedharan; Medicine, Indiana University School of Medicine, Indianapolis, IN.

792   Assessment of Histamine Release and Immunomodulation Induced by Restorative Dental Materials

A. A. Babakhin ¹, A. I. Volozhin², L. N. Kazarina², O. O. Guschina², J. A. Babakhina², L. M. DuBuske³; ¹National Research Center - Institute of Immunology, Ministry of Health of Russia, Moscow, RUSSIAN FEDERATION, ²Moscow Medical and Dental University, Moscow, RUSSIAN FEDERATION, ³Immunology Research Institute of New England, Gardner, MA.

793   Cysteinyl Leukotrienes (CysLTs) Stimulate Eosinophil Degranulation in a CysLT1 Receptor Antagonist Independent Fashion

S. Early, K. Hise, L. Borish, J. W. Steinke; Beirne Carter Center for Immunology Research, University of Virginia, Charlottesville, VA.

794   BALB/c Mice Have Exaggerated IL-10 Response to Murine P. carinii.

D. G. Barstow, Jr., S. Ruan, X. Rudner, J. Shellito; LSU HSC, New Orleans, LA.

Poster Session

4204

Monday, March 06, 2006 9:45 am to 10:45 am

Vaccines and Other Basic and Clinical Immunology Topics

795   Respiratory Syncytial Virus-Induced Airway Dysfunction Depends on the Virus Strain

M. L. Moore ¹, N. W. Lukacs², B. D. Rudd², V. V. Polosukhin¹, M. H. Chi¹, K. Goleniewska¹, J. F. O'Neal¹, R. S. Peebles, Jr.¹; ¹Division of Allergy, Pulmonary, & Critical Care Medicine, Vanderbilt University Medical School, Nashville, TN, ²Department of Pathology, University of Michigan Medical School, Ann Arbor, MI.

796   Adsorption of Allergens to Aluminium Hydroxide Adjuvant Induces only Minor or No Structural Changes in Freshly Prepared Vaccines

C. Hejl, K. Meno, H. Ipsen; Research Department, ALK-Abello, Hørsholm, DENMARK.

797   Apoptosis Indices in Patients with Acute and Chronic Viral Hepatitis C and Mixed Hepatitis B and C

V. V. Tarasiuk¹, L. P. Titov ¹, D. A. Charnashey¹, L. S. Jmurovskaya¹, L. M. DuBuske²; ¹Research Institute for Epidemiology & Microbiology, Minsk, BELARUS, ²Immunology Research Institute of New England, Gardner, MA.

798   Resveratrol Induces Apoptosis in an Activated B-Cell Lymphoma Line OCI-LY3

A. C. Faber, T. C. Chiles; Boston College Department of Biology, Chestnut Hill, MA.

799   Identification of Conformational Epitopes on Jun A 1, the Major Allergen of Mountain Cedar Pollen

R. Tiwari, D. Matalon, B. Ning, E. Czerwinski, T. Midoro-Horiuti, R. M. Goldblum; Pediatrics, University of Texas Medical Branch, Galveston, TX.

800   Chest Pain: An Unrecognized Side Effect Temporally Associated with Influenza Vaccine

M. R. Kaplan, M. Nelson, M. Klote, R. Engler; Allergy/ Immunology, Walter Reed Army Medical Center, Washington, DC.

801   A Simple Risk Score to Predict Intravenous Immunoglobulin Non-Responders in Patients with Kawasaki Disease

T. Kobayashi; Department of Pediatrics and Developmental Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, JAPAN.

802   Effect of Simvastatin on Nitric Oxide Production and Lipid Peroxidation of Chondrocytes.

E. J. Dombrecht, K. Aerts, C. B. De Tollenaere, V. Seynhaeve, C. H. Bridts, D. G. Ebo, J. F. Van Offel, W. J. Stevens, L. S. De Clerck; Immunology - Allergology - Rheumatology, University Antwerp, Antwerp, BELGIUM.

803   Evaluation of Clinical Outcomes in Children with Chronic Otitis Media (COM) and Chronic Rhinosinusitis (CRS) in Comparison with Pneumovax^® Responses and Immunoparameters

C. M. Ward, L. Geng, A. Cushing-Ruby, H. Jyonouchi; UMDNJ, Newark, NJ.

804   Immune Response to Influenza Vaccination in Subjects Self Reporting Seasonal Allergic Rhinitis

S. T. Chang, M. M. Klote, M. R. Nelson, R. J. M. Engler; Walter Reed Army Medical Center, Washington, DC.

805   Determination of Interleukin 6 (IL-6) and Secretory Immunoglobulin A (Ig As) in Human Milk (Colostrum)

D. C. Rodríguez, D. M. Larrauri, J. L. Liporaci, E. Martinez, L. J. Feo, D. Fernandez, C. Rodriguez, M. A. Velasquez; Medicina Preventiva y Social, Universidad Centrooccidental Lisandro Alvarado, Barquisimeto, Estado Lara, VENEZUELA.

806   Changes in Anti-Pertussis Titers in Adults Following Pertussis Vaccine

S. I. Krassilnikova, C. Mende, T. J. Craig; Hershey Medical Center, Hershey, PA.

807   Enhancement to the Immunogenicity DNA Vaccine Expressing Hepatitis B Virus Core Antigen by Co-injection Flt3 Ligand as a Gene Adjuvant

w. zhang ¹, S. Dong²; ¹Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA, ²Key laboratory of Medical Molecular Virology, Shanghai Medical College of Fudan University, Shanghai, CHINA.

808   Intraepithelial Endocrine Cell Population in Larynx from Ovalbumin (OVA) Sensitized and Orally Challenged Rabbits

M. A. Vinuesa, N. D. Bassan, G. H. Fontanella, S. Chaparro, N. Caviglia, G. Kieffer; Catedra de Histologia, Facultad de Ciencia Medicas, Rosario, ARGENTINA.

809   Toll-Like Receptor 2 as a Functional Receptor to Respiratory Syncytial Virus

Y. Inoue, N. Shimojo, T. Arima, Y. Kohno; Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, JAPAN.

810   Idiopathic Granulomatous Myositis Successfully Treated with IVIG

J. Y. Patel, D. P. Huston, G. F. Duna; Section of Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX.

811   Macrophage Activation Syndrome (MAS) as a Debut of Systemic Lupus Erythematosus (SLE) in a Child.

L. M. Kahn Benarroch, G. Sterba, M. Bosque; Hospital de Clinicas Caracas, Caracas, VENEZUELA.

812   Is Screening with C4 Complement Level Enough to Exclude Hereditary Angioedema?

S. Grigoriadou, M. Duddridge; Immunology, University Hospitals of Leicester NHS Trust, Leicester, UNITED KINGDOM.

813   Is Tissue Transglutaminase (tTG) IgA Sufficient for the Diagnosis of Celiac Disease

F. Zarabpouri, J. Popov, D. Keno, M. Glovsky, A. Sferruzza; Immunology, Quest Diagnostics, San Juan Capistrano, CA.

814   Variation of Basophil CD63 Expression in Drug Hypersensitivity Patients According to their in Vivo Test

V. Kvedariene¹, M. Rongier², P. Demoly¹, B. Arnoux ²; ¹Maladies Respiratoires, Hopital A de Villeneuve, Service d'Allergologie, Montpellier Cedex 05, FRANCE, ²U454, INSERM, Montpellier Cedex 05, FRANCE.

815   Validation of a New ImmunoCAP^TM Test for Detecting Allergen-Specific IgE to Two Spotted Spider Mite

H. Park, Y. Ye, S. Kim, C. Suh, D. Nahm; Allergy & Rheumatology, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA.

816   Comparative Study of ImmunoCAP^TM and ELISA for Detecting Allergen-Specific IgE to Japanese Hop Pollen

H. Park, Y. Ye, S. Kim, D. Nahm, C. Suh; Allergy & Rheumatology, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA.

817   In Vitro Detection of Low Levels of Specific IgE

D. HOVANEC-BURNS; Product Support Allergy & Infectious Disease, Diagnostic Products Corporation, Los Angeles, CA.

818   Diagnosis of Chronic Granulomatous Disease (CGD) in Adults

J. Martín-Lázaro ¹, S. Urban², V. García-Patos², M. Hernández², T. Español², I. Caragol²; ¹Allergy, Hospital Juan Canalejo, La Coruna, SPAIN, ²Immunology, Hospital Valle de Hebron, Barcelona, SPAIN.

819   A Case of Adult-Onset pFAPA

M. A. Cavuoto, V. R. Bonagura; Allergy and Immunology, North Shore-Long Island Jewish Health System, Great Neck, NY.

820   Unusual Presentation of HTLV-induced Adult T-cell Lymphoma/leukemia

I. Tanaka ¹, A. Edwards², K. Singh³, L. Bielory⁴; ¹UMDNJ - New Jersey Medical School, Newark, NJ, ²Medicine, UMDNJ - New Jersey Medical School, Newark, NJ, ³Medicine and Pediatrics, UMDNJ - New Jersey Medical School, Newark, NJ, ⁴Allergy, Immunology and Rheumatology, UMDNJ - New Jersey Medical School, Newark, NJ.

821   Suscefull Treatment of Posherpetic Neuralgia with Transfer Factor

E. Cervantes-Trujano, A. Rodríguez-Flores, A. Portugués-Díaz, U. Pacheco-García, R. Ondarza-Aguilera, R. Cortés-Gómez, S. Estrada-Parra; Immunology, National School of Biological Science, National Polytechnic Institute, México, D.F., MEXICO.

822   IgM - IgG Antibodies against Citomegalovirus and Epstein Barr Virus in SLE.

M. D. C. Petrola ¹, L. Rondon², M. E. Flores Chávez¹, M. T. Pacheco¹; ¹Immunology Unit, University of Carabobo, Valencia, VENEZUELA, ²Immunology Unit, CHET, Valencia, VENEZUELA.

823   Serum Levels of Interleukin 6 in Patient with Diagnostic of IschemicCardiopathy

M. E. Flores Chávez, C. G. Petrola, M. R. Chacon de Petrola, I. Petrola, M. T. Pacheco; Medicine, Universidad de Carabobo, Valencia, VENEZUELA.

Poster Session

4205

Monday, March 06, 2006 9:45 am to 10:45 am

Asthma: Epidemiology, Risk Factors, Intervention and Public Health

824   Classification of Pre-School Wheezers Using Impulse Oscillometry and Atopy Distinguishes Those with Increased Morbidity

A. H. Liu ^1,2, M. Ellison^3,4, S. Tong¹, J. L. Robinson⁵, M. D. Klinnert^1,6; ¹Pediatrics, National Jewish Medical and Research Center, Denver, CO, ²Pediatrics, University of Colorado School of Medicine, Denver, CO, ³Biostatistics, National Jewish Medical and Research Center, Denver, CO, ⁴Biostatistics, University of Colorado School of Medicine, Denver, CO, ⁵Family Studies, University of Connecticut, Storrs, CT, ⁶Psychiatry, University of Colorado School of Medicine, Denver, CO.

825   Asthma and Allergies in Preschool Children: Prevalence and Risk Factors

G. W. K. Wong, T. F. Leung, E. K. H. Liu, T. F. Fok; Pediatrics, Chinese University of Hong Kong, Hong Kong SAR, CHINA.

826   The Positive Relationship of Atopy to Obesity in Women is Negatively Correlated to Serum Leptin

M. R. Windt ^1,2, A. R. Tagliaferro³, V. J. Vieira¹, A. M. Ronan¹; ¹Department of Animal & Nutritional Sciences, University of New Hampshire, Durham, NH, ²Center for Asthma Allergy and Respiratory Disease, North Hampton, NH, ³Department of Animal & Nutritional Sciences, University of New Hampshire, Durham, NH.

827   Demographic and Clinical Characteristics of Children and Adolescents with Severe or Difficult-to-Treat Asthma

B. Chipps ¹, S. J. Szefler², J. H. Lee³, T. Haselkorn⁴, D. R. Mink⁵, Y. Deniz³, F. E. Simons⁶; ¹Capital Allergy and Respiratory Disease Center, Sacramento, CA, ²National Jewish Medical and Research Center, Denver, CO, ³Genentech, Inc., South San Francisco, CA, ⁴EpiMetrix, Inc., Sunnyvale, CA, ⁵Ovation Research Group, San Francisco, CA, ⁶University of Manitoba, Winnipeg, MB, CANADA.

828   Mouse Allergen Exposure, Wheeze, and Atopy in the First Seven Years of Life

W. Phipatanakul ^1,2, J. C. Celedon³, C. D. Ramsey², D. L. Sredl⁴, S. T. Weiss³, D. R. Gold²; ¹Pediatric Allergy and Immunology, Children's Hospital, Boston, Harvard Medical School, Boston, MA, ²Respiratory Epidemiology, Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ³Respiratory Epidemiology, Channing Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁴Respiratory Epidemiology, Channing Laboratory, Harvard Medical School, Boston, MA.

829   Household Mouse Allergen Exposure Predicts Asthma Morbidity in Inner-city Pre-School Children

E. C. Matsui ¹, P. A. Eggleston¹, J. A. Krishnan², P. Breysse³, C. Rand², G. B. Diette²; ¹Department of Pediatrics, Johns Hopkins University School Medicine, Baltimore, MD, ²Department of Medicine, Johns Hopkins University School Medicine, Baltimore, MD, ³Department of Environmental Health Sciences, Johns Hopkins University School of Public Health, Baltimore, MD.

830   Reduction of Endotoxin and Glucan Exposures in The Louisa/Keokuk Environmental Intervention Project (LEIP) for Rural Childhood Asthma

P. S. Thorne, E. A. Chrischilles, A. K. W. Kuehl, K. M. Kelly, N. Metwali, L. M. Harris, M. E. O'Neill, A. K. Quella, R. E. Walker; College of Public Health, The University of Iowa, Iowa City, IA.

831   Sensitization and Asthma Severity in Inner City African Americans (AA) and Latino Americans (LA) in a Large Community Based Cohort

R. Kumar ¹, C. Saltoun², G. Mosnaim³, L. C. Grammer², R. Durazo-Arvizu⁴, L. Stierman⁵, J. Shannon⁶, K. B. Weiss^5,7; ¹Allergy, Childrens’ Memorial Hospital, Chicago, IL, ²Allergy, Northwestern University, Chicago, IL, ³Allergy, Rush University, Chicago, IL, ⁴Biostatistics, Loyola University Medical School, Chicago, IL, ⁵Institute for Healthcare Studies, Northwestern University, Chicago, IL, ⁶Pulmonary and Critical Care Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, IL, ⁷Institute for Healthcare Studies, Hines VA, Chicago, IL.

832   Fractional Exhaled Nitric Oxide (FeNO) is a Marker of Allergic Inflammation in High Risk 5 Year Old Children

L. E. Pleiss, M. Evans, E. L. Anderson, D. F. DaSilva, T. E. Pappas, K. A. Roberg, K. Sullivan - Dillie, C. J. Tisler, R. Gangnon, J. E. Gern, R. F. Lemanske; Medical School, University of Wisconsin- Madison, Madison, WI.

833   Prevalence and Severity of Asthma among Adolescents and its Relationship with the Body Mass Index

V. E. Cassol¹, T. M. Rizzato¹, S. P. Teche¹, D. F. Basso², V. N. Hirata³, M. Maldonado⁴, E. Colpo⁵, D. Solé ⁶; ¹Pediatrics/Division of Pediatric Pneumology, Federal University of Santa Maria, Santa Maria, BRAZIL, ²Nutrition, Federal University of Santa Catarina, Florianópolis, BRAZIL, ³Epidemiology, Federal University of Pelotas, Pelotas, BRAZIL, ⁴Physiology of Exercise, Federal University of Santa Maria, Santa Maria, BRAZIL, ⁵Nutrition, Federal University of Santa Maria, Santa Maria, BRAZIL, ⁶Pediatrics/Division of Allergy and Clinical Immunology, Federal University of São Paulo-Escola Paulista de Medicina, São Paulo, BRAZIL.

834   IgE to Cockroach Allergens and Asthma

A. Togias ¹, J. Poyser¹, S. Satinover², D. Collins¹, T. Richards¹, T. Green¹, E. Horowitz¹, J. Woodfolk²; ¹Johns Hopkins University, Baltimore, MD, ²University of Virginia, Charlottesville, VA.

835   A Clinical-Based Retrospective Cohort Study of Incidence Asthma in Adults with Allergic Rhinitis: Importance of Cigarette Smoking

R. Polosa; Dipartimento di Medicina Interna, University of Catania, Catania, ITALY.

836   A Study of Cord IgE and Birth Order

L. L. Shue; Allergy and Immunology, HFHS, Detroit, MI.

837   Can Parents Reliably Identify Asthma in Infants?

H. J. Chong Neto ¹, C. Dela Bianca², D. Solé², N. Rosario¹, J. Mallol³; ¹Allergy, University of Parana, Curitiba, BRAZIL, ²Allergy, University of Sao Paulo, Sao Paulo, BRAZIL, ³Respiratory Infant Diseases, University of Santiago, Santiago, CHILE.

838   Characteristics of Children with Emergency Department Visits for Asthma

H. C. Wang ¹, S. E. Hodgdon², A. K. Glasofer², S. J. McGeady¹, E. Yousef¹; ¹Division of Allergy and Immunology, Thomas Jefferson University, duPont Hospital for Children, Wilmington, DE, ²Department of Pediatrics, Thomas Jefferson University, duPont Hospital for Children, Wilmington, DE.

839   Nation-wide Prevalence of Symptoms of Asthma and Wheezing in all Age Groups of Japanese Population Sampled by a Modified Random Digit Dialing Method

A. Aota ^1,2, Y. Ohya^1,2, A. Saitoh^1,2, M. Futamura^1,2, M. Akashi^1,2, N. Kojima^1,2, K. Akiyama², K. Takahashi², T. Nakagawa², F. Kobayashi², A. Eboshida², H. Nakamura², H. Odajima², Y. Adachi², A. Akasawa^1,2; ¹National Center for Child Health and Development, Tokyo, JAPAN, ²Japanese Asthma Survey Group, Tokyo, JAPAN.

840   Dietary Factors Associated with Wheezing in a Birth Cohort at High Risk for the Development of Asthma/Allergy at Age 5 Years

H. Lai ¹, Z. Zhang¹, L. Davis², S. Shoff¹, M. Nord¹, K. Roberg¹, E. Anderson³, J. Gern³, R. Lemanske¹; ¹Nutritional Sciences, University of Wisconsin-Madison, Madison, WI, ²UW Hospital and Clinics, University of Wisconsin-Madison, Madison, WI, ³PEDIATRICS, University of Wisconsin-Madison, Madison, WI.

841   Variation of Endotoxin Concentrations by Location within Homes

D. R. Ownby ¹, E. L. Peterson², L. K. Williams³, G. Wegienka², C. C. Johnson²; ¹Pediatrics, Medical College of Georgia, Augusta, GA, ²Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI, ³Medicine, Henry Ford Health System, Detroit, MI.

Poster Session

4206

Monday, March 06, 2006 9:45 am to 10:45 am

Allergenic Products: Diagnostics and Vaccines

842   Multiple Screening Test for Assessment of Environmental Allergen Exposure

A. Tsay, C. Franck, A. Chapman, B. Saric, L. D. Vailes, M. D. Chapman; Indoor Biotechnologies, Inc., Charlottesville, VA.

843   Use of Recombinant Proteins for Diagnosis of Cockroach Allergy in Patients with Asthma and/or Rhinitis Living in Brazil

A. R. Santos¹, M. C. Rodrigues¹, M. Thiesen¹, A. S. Zampolo¹, V. P. L. Ferriani², L. Arruda ¹; ¹Medicine, School of Medicine of Ribeirão Preto, Ribeirão Preto, BRAZIL, ²Pediatrics, School of Medicine of Ribeirão Preto, Ribeirão Preto, BRAZIL.

844   A Semi Quantitative Poc Test for Rapid Detection of Specific Ige Antibodies

M. Nystrand¹, A. Kober¹, L. Soderstrom ²; ¹Pharmacia Diagnostics AB, Uppsala, SWEDEN, ²Pharmacia Doagnostics AB, Uppsala, SWEDEN.

845   Quantitation of Mouse-Human Chimeric Allergen Specific IgE Antibodies with ImmunoCAP™ Technology

A. Kober, H. Perborn; Pharmacia Diagnostics AB, Uppsala, SWEDEN.

846   Group 1 Major Allergen, Art v 1, in Artemisia Species Found in the United States

G. Plunkett ¹, L. Jimeno²; ¹ALK-Abello, Inc., Round Rock, TX, ²ALK-Abello, Madrid, SPAIN.

847   Three Antigens for Screening in Perennial Allergic Airway Diseases

P. Supakthanasiri, H. Chantaphakul, K. Ruxrungtham; Division of allergy and immunology, Department of medicine, Chulalongkorn university, Bangkok, THAILAND.

848   Immunomodulatory Properties of Recombinant Lactic Acid Bacteria Encoding a Major House-dust Mite Allergen

P. Rigaux ¹, C. Daniel², C. Ratajczak³, B. Pot², J. Pestel³, A. Jacquet¹; ¹Service de Génétique Appliquée, Université Libre de Bruxelles, Gosselies, BELGIUM, ²Laboratoire de Bactériologie des Ecosytèmes, Institut de Biologie de Lille, Lille, FRANCE, ³Inserm U416, Institut Pasteur de Lille, Lille, FRANCE.

849   Changes in the Levels of D. farinae Specific IgE, IgG₄ and Their Immunoblotting Patterns After the Long-term House Dust Mite Specific Immunotherapy

Y. W. Lee ¹, S. Y. Choi², E. K. Lee², J. W. Park^1,2, C. S. Hong^1,2; ¹Internal Medicine, Yonsei University, College of Medicine, Seoul, REPUBLIC OF KOREA, ²Institute of Allergy, Yonsei University, College of Medicine, Seoul, REPUBLIC OF KOREA.

850   Comparison of Allergenicity and Immunogenicity of an Intact Allergen Extract (Alutard SQ^®) and 4 Commercially Available Allergoid Products for Birch Pollen Immunotherapy

L. Lund, P. A. Würtzen, G. Lund, H. Henmar; Research, ALK-Abelló, Hoersholm, DENMARK.

851   Longitudinal Study of Sublingual Immunotherapy with SQ Standardized Grass Allergen Tablet - Interim Safety Results

R. Dahl¹, A. Kapp², M. Ribel ³, S. R. Durham⁴; ¹Department of Respiratory Diseases, Aarhus University Hospital, Aarhus, DENMARK, ²Department of Dermatology and Allergology, Hannover Medical University, Hannover, GERMANY, ³Clinical Development, ALK-Abelló, Horsholm, DENMARK, ⁴Department of Allergy and Clinical Immunology, Royal Brompton Hospital, London, UNITED KINGDOM.

852   New Onset Vaccine Hypersensitivity in a Child after Liver Transplant

P. P. Ponda ¹, A. Nowak-Wegrzyn²; ¹Clinical Immunology, Mount Sinai Medical Center, New York, NY, ²Pediatric Allergy and Immunology, Mount Sinai Medical Center, New York, NY.

853   Local Reactions and Pain to Trivalent Inactivated Influenza Vaccine (TIV): Impact of Gender and Dose/Volume (DV)

M. M. Klote, M. R. Nelson, R. J. M. Engler; Allergy Immunology, Walter Reed Army Medical Center, Washington, DC.

854   Comparison of Three Independently Produced Alternaria r Alt a1

H. Sanchez, M. Opsahl, R. K. Bush; Research, William S. Middleton VA Hospital, Madison, WI.

855   Real Time Monitoring of IgE Sensitization (ReTiME): A New Module of the Allergome Platform for Web-based Studies

A. Mari ¹, E. Scala², G. Carabella³; ¹Allergy Data Laboratories, s.c., Latina, ITALY, ²Experimental Allergology Unit, IDI-IRCCS, Rome, ITALY, ³Panservice, SAS, Latina, ITALY.

Poster Session

4207

Monday, March 06, 2006 9:45 am to 10:45 am

Adverse Drug Reactions

856   Time Course of Allergic Reactions to Drugs

P. Bousquet, H. Co-Minh, B. Arnoux, J. Bousquet, P. Demoly; Allergology - Services des Maladies Respiratoires, University Hospital, Montpellier Cedex 5, FRANCE.

857   291 Patients with Self-Reported Drug Reactions -is it Worth Testing?

S. Wöhrl, K. Vigl, G. Stingl; Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases (DIAID), Medical University of Vienna, Vienna, AUSTRIA.

858   Increased Adverse Drug Reactions to Cephalosporins in Patients with a Positive Penicillin Skin Test

M. A. Park¹, P. J. Klemawesch ², P. J. Markus¹; ¹Allergy and Immunology, Mayo Clinic, Rochester, MN, ²Internal Medicine, Mayo Clinic, Jacksonville, FL.

859   Benzocaine Anaphylaxis

R. F. Lockey, A. T. Vu; University of South Florida - College of Medicine and James A. Haley Veterans’ Hospital, Tampa, FL.

860   Clinical Presentation, Evaluation, and Management of Patients with Carboplatin Hypersensitivity

P. E. Hesterberg ¹, A. Banerji¹, E. Oren¹, R. T. Penson², M. V. Seiden², C. N. Krasner², J. T. Wong¹; ¹Allergy,Immunology, Rheumatology, Massachusetts General Hospital, Boston, MA, ²Gillette Center for Womens Cancers, Massachusetts General Hospital, Boston, MA.

861   Adverse Events Associated with Home Administration of Parenteral Drugs

C. H. Katelaris ¹, E. A. Cheong², C. Sisson², E. A. Anderson³, K. Byth⁴; ¹Dept Clinical Immunology and Allergy, Westmead Hospital, Sydney, AUSTRALIA, ²PACC, Westmead Hospital, Sydney, AUSTRALIA, ³Dept of Pharmacy, Westmead Hospital, Sydney, AUSTRALIA, ⁴Millenium Institute, Westmead Hospital, Sydney, AUSTRALIA.

862   Solid Organ Transplant Acquired Food Allergy in Children Receiving Macrocyclic Lactones as Major Immunosuppressant

Ö. Özdemir, A. A. Arrey-Mensah, R. U. Sorensen; Pediatric Allergy/Immunology, Louisiana State University Health Sciences Ctr., New Orleans, LA.

863   The Penicillin Skin Test has a High Negative Predictive Value and Helps to Modify the Use of Antibiotics in Patiens with History of Beta-Lactam Allergy

G. Alvarez del Real ¹, M. E. Rose¹, J. Hammel², S. M. Gordon³, M. E. Arroliga¹; ¹Allergy and Immunology, The Cleveland Clinic Foundation, Cleveland, OH, ²Quantitative Health Sciences, The Cleveland Clinic Foundation, Cleveland, OH, ³Infectious Disease, The Cleveland Clinic Foundation, Cleveland, OH.

864   Drug Provocation Test (DPT) in Patients with a History of Macrolide Allergy

N. Nguyen Luu, A. DesRoches, M. Primeau; Pediatrics, Saint-Justine Hospital, University of Montreal, Montreal, PQ, CANADA.

865   Management of Anaphylaxis from the Neuromuscular Blocking Agent Rocuronium Bromide: Can We Go with the Flow

C. H. Bridts, D. G. Ebo, M. M. Hagendorens, C. H. Mertens, L. S. De Clerck, W. J. Stevens; Immunology - Allergology - Rheumatology, University Antwerp, Antwerp, BELGIUM.

866   Use of Beta Blockers does not Affect the Performance of Penicillin Skin Testing

M. E. Rose¹, G. Alvarez del Real ¹, J. Hammel², M. E. Arroliga¹; ¹Allergy and Immunology, The Cleveland Clinic Foundation, Cleveland, OH, ²Quantitative Health Sciences, The Cleveland Clinic Foundation, Cleveland, OH.

867   The Value of Skin Testing in the Diagnosis of Betalactam Allergy

M. J. Torres¹, E. Martin¹, C. Rondon¹, C. Mayorga², J. L. Rodriguez-Bada², M. S. Fuentes¹, I. Doña¹, N. Blanca¹, M. Blanca ¹; ¹Allergy Service, Carlos Haya Hospital, Malaga, SPAIN, ²Research Laboratory, Carlos Haya Hospital, Malaga, SPAIN.

868   Local Anesthetic Allergy Characterized by Type IV Reactions in Patients Who Received Dental Anesthesia

J. Melamed, W. N. Beaucher; Allergy and Asthma Specialists, Chelmsford, MA.

869   Successful Intravenous “Rush” Drug Desensitization to Meropenam Following Omalizumab Administration

L. R. Hennessey ¹, R. Honicky², S. Sudhanthar², A. P. Dumpit³; ¹Internal Medicine, and Pediatrics and Human Development, Michigan State University College of Human Medicine, East Lansing, MI, ²Pediatrics and Human Development, Michigan State University College of Human Medicine, East Lansing, MI, ³Emergency Medicine, Edward W. Sparrow Hospital, Lansing, MI.

870   Allergy Consultation and Skin Testing Benefits Significantly the Selection of the Antibiotic for Antibacterial Prophylaxis Preoperatively (ABPPO) in Patients Who Report Allergy to Penicillin (PRAP)

E. Frigas, P. J. Markus, B. J. Narr, D. R. Danielson, P. A. Park, K. A. Bachman, P. A. Harris, M. M. O'Byrne, K. E. Kloos, G. W. Volcheck, H. Kita, D. R. Schroeder; Division of Allergic Diseases & Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN.

871   Low MMR Vaccine Uptake amongst Children with Egg Allergy

A. T. Fox ¹, D. Maisnam¹, J. Eliahoo²; ¹Paediatric Allergy, St Mary's Hospital, London, UNITED KINGDOM, ²Statistical Advisory Service, Imperial College, London, UNITED KINGDOM.

872   Risks And Benefits Of Withholding Beta Blockers During Aspirin Desensitization

L. V. Sachs ^1,2, S. Zubair³, L. Fisher⁴, E. Pratt⁴, J. Gibbs⁴, S. Chegini⁴, J. Larson⁴, T. Craig⁴; ¹Penn State University Hershey Medical Center, Harrisburg, PA, ²Internal Medicine, PinnacleHealth System, Harrisburg, PA, ³College of Medicine, Penn State University Hershey Medical Center, Hershey, PA, ⁴Allergy and Immunology, Penn State University Hershey Medical Center, Hershey, PA.

873   Iodixanol May be Agent of Choice in Patients with Prior Anaphylactoid Reactions to Radiocontrast Media

P. K. Mehra, J. Y. Lee, R. A. Simon; Division of Allergy, Asthma, and Immunology, Scripps Clinic, La Jolla, CA.

874   Assessment of Allergic Skin Reactions and their Inhibition by Antihistamines using Photoplethysmography Imaging (PPGI)

C. R. Blazek ¹, H. F. Merk¹, H. Schmid-Schoenbein², M. Huelsbusch³, V. Blazek³; ¹Department of Dermatology and Allergology, University Hospital of RWTH Aachen, Aachen, GERMANY, ²Department of Physiology, University Hospital of RWTH Aachen, Aachen, GERMANY, ³Institute of High Frequency Technology, RWTH Aachen University, Aachen, GERMANY.

875   Anaphylaxis to Multiple HIV-1 Protease Inhibitors (PIs) with Successful Desensitization to Ritonavir

P. Saengaram, H. Chantaphakul, K. Ruxrungtham; Division of Allergy and Clinical Immunology, Department of Medicine, Chulalongkorn University, Bangkok, THAILAND.

876   A Case Of Carbamazepine Induced Onychomadesis

K. You¹, J. Jeong ², S. Nahm², E. Kim³; ¹Internal Medicine, Kun-Kuk University Hospital, Seoul, REPUBLIC OF KOREA, ²Internal Medicine, ILSAN PAIK HOSPITAL, Kyungki-do, REPUBLIC OF KOREA, ³Internal Medicine, Dong-Kuk University Hospital, Kyungki-do, REPUBLIC OF KOREA.

877   Anaphylaxis After Epidermal Contact with Cefotiam Hydrochloride

J. Jeong ¹, K. You², S. Nahm¹, E. Kim³; ¹Internal Medicine, ILSAN PAIK HOSPITAL, Kyungki-do, REPUBLIC OF KOREA, ²Internal Medicine, Kun-Kuk University, Seoul, REPUBLIC OF KOREA, ³Internal Medicine, Dong-Kuk University, Kyungki-do, REPUBLIC OF KOREA.

878   Drug-Induced Petechial Eruption during Aspirin Therapy in a Patient with Positive Aspirin Allergy History but Negative Oral Challenge

A. P. Hope, R. A. Simon, K. M. Woessner; Allergy and Immunology, Scripps Clinic/Green Hospital, La Jolla, CA.

879   Enhanced Immediate Allergic Skin Test Responses to Blomia tropicalis in Urticaria/Angioedema NSAID-Sensitive Subjects

M. Sanchez-Borges, A. Capriles-Hulett, F. Caballero-Fonseca; Allergy and Clinical Immunology, Centro Medico-Docente La Trinidad, Caracas, VENEZUELA.

880   Potential Adverse Reaction from Complementary and Alternative Medicines (CAM) Brought in from Overseas

G. Wong; Vancouver General Hospital, University of British Columbia, Vancouver, BC, CANADA.

881   Efficacy of Percutaneous and Intradermal Skin Tests, and Patch Test to Predict Hypersensitivity to Trimetropin-Sulfametoxazol (TMP-SMX) in Hiv-infected Patients

P. Mantilla Guevara, D. D. Delgado, G. R. Hernandez. Vivas, V. Quintero Parada; Instituto de Oncología y Hematología, Universidad Central de Venezuela, Ministerio de Salud y Desarrollo Social, Caracas, VENEZUELA.

882   Severity of Allergic Reactions to Drugs

L. Bousquet-Rouanet, P. Bousquet, B. Arnoux, J. Bousquet, P. Demoly; Exploration des Allergies, CHU Montpellier, Montpellier Cedex 5, FRANCE.

883   Allergic Reaction During Challenge Test for Local Anaesthetics

S. Isola, G. Santoro, P. L. Minciullo, P. Galati, B. Ferlazzo, S. Gangemi; Department of Human Pathology, School and Operative Unit of Allergy and Clinical Immunology, Messina, ITALY.

884   Serum-Sickness-Like Reactions Following Placement of Sirolimus-Eluting Stents

J. S. Rana ¹, J. Sheikh²; ¹Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Medicine, Beth Israel Deaconess Medical Center, Boston, MA.

885   Contact Allergy to Inhaled Budesonida

D. V. Tovar Flores; Alergia, Hospital Gregorio Marañon, Madrid, SPAIN.

886   Lichenoid Drug Eruption Associated with TNF Inhibitors

T. M. Wilson ¹, G. H. Louie², A. V. Rapkiewicz³, B. Foster⁴, M. L. Turner³, R. Goldbach-Mansky², R. L. Rabin⁵, C. Prussin⁴; ¹Laboratory of Allergic Diseases, National Institutes of Health, Bethesda, MD, ²NIAMS, National Institutes of Health, Bethesda, MD, ³NCI, National Institutes of Health, Bethesda, MD, ⁴Laboratory of Allergic Disease, National Institutes of Health, Bethesda, MD, ⁵CBER, FDA, Bethesda, MD.

887   A Three Year Old Girl with Recurrent Urticaria Triggered by Multiple Inhaled Beta-Agonist Class Medications

B. A. Becker ¹, B. J. Mark², M. S. Dykewicz²; ¹Pediatrics, Saint Louis University School of Medicine, Saint Louis, MO, ²Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO.

888   Modified Desensitization Protocol Using Two Formulations of L-Asparaginase in a Pediatric Patient with Recurrent Acute Lymphoblastic Leukemia (ALL)

M. H. LeBras, S. L. Saccente, R. L. Saylors, T. T. Perry, S. M. Jones, A. M. Scurlock; UAMS/AR Children's Hospital, Little Rock, AR.

889   A Case Report of Anticonvulsant Hypersensitivity Syndrome (AHS): Importance of Early Recognition and Future Avoidance

V. Patel ¹, S. Kearney²; ¹Medicine, Lehigh Valley Hospital, Allentown, PA, ²Allergy & Immunology, Lehigh Valley Hospital, Allentown, PA.

890   All-Trans Retinoic Acid (ATRA) Desensitization

D. M. Kearney, D. K. Ledford, R. F. Lockey; University of South Florida and James A. Haley Veterans Hospital, Tampa, FL.

891   Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: a Retrospective Study in Chulalongkorn Hospital

A. Sukkul, H. Chantapakul, K. Ruxrungtham; Allergy and Clinical Immunology Division, Chulalongkorn Hospital, BKK, THAILAND.

892   Intravenous Immunoglobulin Therapy-Induced Pompholyx

C. H. Larramendi ¹, J. L. Garcia-Abujeta¹, M. Llombart², R. Sanchez³; ¹Unidad de Alergia, Hospital Marina Baixa, La Vila Joiosa (Alacant), SPAIN, ²Sección de Neumología, Hospital Sant Joan, Sant Joan (Alacant), SPAIN, ³Sección de Neurologia, Hospital Marina Baixa, La Vila Joiosa (Alacant), SPAIN.

893   First Case Report of Dapsone-Induced Neuromuscular Respiratory Impairment

W. S. Micka, P. Korenblat; Barnes Hospital/Washington University School of Medicine, Saint Louis, MO.

894   Trimethoprim-Sulfamethoxazole Desensitization in a VIH-Infected Child

J. M. Del Rio-Chivardi, M. A. Rosas-Vargas, J. A. Luna-Pech, J. J. L. Sienra-Monge, B. E. Del Rio-Navarro; Departamento de Alergia e Inmunología Clínica, Hospital Infantil de Mexico ‘Federico Gomez’, Mexico City, MEXICO.

895   Mesalamine Administration in Allergic Patients with Inflammatory Bowel Disease

J. Yoo, K. Gundling; Allergy/Immunology, UCSF, San Francisco, CA.

896   Contribution of the Basophil Activation Test in the Diagnosis of Wasp Venom Allergy and Follow-Up of Venom Immunotherapy

D. G. EBO, M. M. Hagendorens, A. J. Schuerwegh, L. M. Beirens, C. H. Bridts, L. S. De Clerck, W. J. Stevens; Immunology - Allergology - Rheumatology, University of Antwerp, Antwerp, BELGIUM.

897   High Frequency and Long-Lasting Reactivity of Drug-Specific T-cells after Systemic Drug Hypersensitivity Reactions

A. Beeler; Clinic of Rheumatology and Clinical of Immunology/Allergology, Bern, SWITZERLAND.

Poster Session

4208

Monday, March 06, 2006 9:45 am to 10:45 am

Atopic Dermatitis, Other Eczemas and Immune Mediated Skin Disorders

898   Effects of DA-9102 on Atopic Dermatitis in Animal Models

M. Jung, I. Lee, J. Son, S. Choi, C. Cho, M. Son, J. Rhee, M. Yoo; DONG-A PHARM. CO., LTD, Yongin, REPUBLIC OF KOREA.

899   Anti-Viral Effects of C-C Chemokine Macrophage Inflammatory Peptide 3 Alpha (MIP-3a)

B. Kim ^1,2, J. Streib¹, M. Boguniewicz¹, D. Y. M. Leung¹, M. D. Howell¹; ¹National Jewish Medical and Research Center, Denver, CO, ²Inje University, Seoul, REPUBLIC OF KOREA.

900   House Dust Mite Sublingual Immunotherapy (SLIT) for Atopic Dermatitis (AD) a Randomized Controlled Trial

G. B. Pajno, D. Vita, L. Caminiti, T. Arrigo, F. Lombardo, G. Barberio; Department of Pediatrics - Allergy Unit, University of Messina, Messina, ITALY.

901   Circulating CD4+T Cells with Skin-homing Properties in Atopic Dermatitis

G. N. Drannik ¹, A. I. Kurchenko¹, L. M. DuBuske²; ¹Dept. Clinical Immunology and Allergology, National Medical University, Kiev, UKRAINE, ²Immunology Research Institute of New England, Gardner, MA.

902   Functional Status Following Treatment of Children with Atopic Dermatitis

K. Kelsay, K. Carel, D. L. Bratton, E. W. Gelfand, M. D. Klinnert; National Jewish Medical and Research Center, Denver, CO.

903   Polymorphisms of the Bcl-2 Family Member bfl-1 and the Genetic Predisposition to Atopic Dermatitis

P. D. Arkwright ¹, A. Gray², H. Stewart², V. Pravica², A. A. Fryer³, W. Lenney³, I. V. Hutchinson²; ¹Child Health, University of Manchester, Manchester, UNITED KINGDOM, ²Biological Sciences, University of Manchester, Manchester, UNITED KINGDOM, ³Keele University, Stoke on Trent, UNITED KINGDOM.

904   Role of Natural Killer T-Cells in a Murine Model of Atopic Dermatitis (AD)

A. Elkhal, M. Pichavant, R. Geha, D. Umetsu; immunology, Childrens Hospital Boston, Boston, MA.

905   Alcohol during Pregnancy and Atopic Dermatitis in the Offspring

A. Linneberg ¹, J. Petersen¹, M. Grønbæk², C. Benn³; ¹Research Centre for Prevention and Health, Copenhagen, DENMARK, ²Centre for Alcohol Research, National Institute of Public Health, Copenhagen, DENMARK, ³Danish Epidemiology Science Centre, Statens Serum Institut, Copenhagen, DENMARK.

906   Bacterial DNA and Endotoxin are Higher in the Bedding Dust of People with Atopic Dermatitis

A. D. Leung ¹, A. M. Schiltz¹, A. H. Liu^1,2; ¹Pediatric Allergy and Immunology, National Jewish Medical and Research Center, Denver, CO, ²Pediatrics, University of Colorado School of Medicine, Denver, CO.

907   The Sensitization of House Dust Mite(HDM) and Food Allergen of Atopic Dermatitis in Korean Infants and Young Children

W. SEO; Dept. of Pediatrics, Samsung Medical Center, SEOUL, REPUBLIC OF KOREA.

908   Body Self Concept in Children with Atopic Dermatitis (AD)

B. Novotna ¹, N. Novotna²; ¹Allergology Unit, Dept.Int.Med, University Hospital, Brno, CZECH REPUBLIC, ²Psychology, Charles University, Prague, CZECH REPUBLIC.

909   Role of Eosinophil Cationic Protein as a Predictor for Atopic Dermatitis Flare-ups

E. Yousef; Division of Allergy and Clinical Immunology, DuPont Hospital for Children, Wilmington, DE.

910   Hypoproteinemia, Including Hypogammaglobulinemia, in Infants with Severe Atopic Dermatitis

J. H. Lin, R. L. Roberts, E. R. Stiehm; Dept of Allergy, Immunology, Rheumatology, UCLA, Los Angeles, CA.

911   Geographical and Socio-Economical Factors Enhance Regional Variation of the Prevalence of Atopic Dermatitis in Japan

Y. Ohya, M. Akashi, M. Futamura, N. Kojima, A. Saitoh, A. Aota, A. Akasawa; Division of Allergy, Department of Medical Specialties, National Center for Child Health and Development, Tokyo, JAPAN.

912   Evaluation of Predictors for Persistence of Atopic Dermatitis

N. Ehsan ¹, S. Kung², E. Yousef²; ¹Cecil Community College, North East, MD, ²DuPont Hospital for Children, Wilmington, DE.

913   Expression of Neutrophil Chemoattractants and their Receptors in Subjects with Atopic Dermatitis and Psoriasis

L. G. Bankova, M. Brummet, M. Paltiel, L. Y. McGirt, L. A. Beck; Department of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins University, Baltimore, MD.

914   Turnip Rape and Oilseed Rape Allergy in Children with Atopic Dermatitis: a Case Control Study

T. Reunala ¹, S. Poikonen¹, H. Kautiainen¹, T. Puumalainen², T. Palosuo², K. Turjanmaa¹; ¹Tampere University Hospital, Tampere, FINLAND, ²National Public Health Institute, Helsinki, FINLAND.

915   Cytology of Skin Exudates in Severe Childhood Atopic Dermatitis

I. Nomura ¹, M. Yoshida¹, N. Inoue¹, A. Aota¹, A. Saito¹, M. Futamura¹, M. Akashi¹, M. Narita¹, T. Suda¹, A. Akasawa², Y. Ohya¹; ¹Division of Allergy and Immunology, National Center for Child Health and Development, Tokyo, JAPAN, ²Department of Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, JAPAN.

916   Increased Expression and a Potential Anti-Inflammatory Role of Trail in Atopic Dermatitis

D. Simon ¹, E. Vassina², M. Leverkus³, L. R. Braathen¹, H. Simon²; ¹Dept. of Dermatology, University of Bern, Inselspital, Bern, SWITZERLAND, ²Dept. of Pharmacology, University of Bern, Bern, SWITZERLAND, ³Dept. of Dermatology, University of Magdeburg, Magdeburg, GERMANY.

917   Diagnostic Role of the Atopy Patch Test in Children with Atopic Dermatitis and Food Allergy

L. M. Brunetti, R. Tesse, M. Lore, M. Leone, R. Procacci, O. Sillecchia, M. Mastronardi, D. Locantore, L. Armenio; Department of Pediatrics-U.O. Maggiore, University of Bari, Bari, ITALY.

918   Development of a Classification System for Atopic Dermatitis (AD)

A. DiDario ¹, E. Yousef²; ¹Allergy/Immunology, Thomas Jefferson University, Philadelphia, PA, ²Allergy/Immunology, AI duPont Hospital for Children, Wilmington, DE.

919   The Classification between IgE and Non-IgE Mediated Atopic Dermatitis in Korean Children

J. Lee ¹, J. Jung², J. Kim³, C. Kim⁴, Y. Park⁵; ¹Pediatric allergy, Masan samsung hospital, Masan si, REPUBLIC OF KOREA, ²Pediatric allergy, Dong-A university hospital, Pusan, REPUBLIC OF KOREA, ³Pediatric allergy, Ulsan University hospital, Ulsan, REPUBLIC OF KOREA, ⁴Pediatric allergy, Kwan-Dong University hospital, Seoul, REPUBLIC OF KOREA, ⁵Pediatric allergy, Kyun-kuk university hospital, Seoul, REPUBLIC OF KOREA.

920   The Differences and the Correlation with the Clinical Severity between Food (Milk, Egg, and Soybean) Specific and House Dust Mite Specific Atopic Dermatitis

J. Oh ¹, S. Shin², H. Lee²; ¹Pediatrics, Hanyang University Guri Hospital, Kyunggi-do, REPUBLIC OF KOREA, ²Pediatrics, Hanyang University Guri Hospital, Seoul, REPUBLIC OF KOREA.

921   Factors Involved Between Ige Mediatied and Non-ige Mediated Atopic Dermatitis in Child and there Use of Complementary Alternative Medicine

W. Kim ¹, H. Yoon²; ¹pediatrics, Inje University, Seoul, REPUBLIC OF KOREA, ²pediatrics, Hallym University, Seoul, REPUBLIC OF KOREA.

922   A Muckle-Wells Syndrome Kindred Confirmed by Cias1 Dna Sequencing

M. R. Gupta ¹, G. Alvarez Del Real¹, F. H. Hsieh¹, K. A. Knauer²; ¹Allergy and Immunology, Cleveland Clinic, Cleveland, OH, ²Internal Medicine-Division of Allergy and Immunology, Case Western Reserve University School of Medicine, Cleveland, OH.

923   An Autoimmune Blistering Skin Disorder: Paraneoplastic Pemphigus (PNP) In Association With A Breast Neoplasm

P. Buddiga; Baz Allergy, Asthma & Sinus Center, Fresno, CA.

924   Induction of a Pathergy-Like Reaction Following Prick Skin Testing

T. L. Johnson, II ¹, P. McCleskey², M. Rathkopf¹, J. Meffert², L. L. Hagan¹; ¹Allergy/Immunology, Wilford Hall Medical Center, Lackland AFB, TX, ²Dermatology, Wilford Hall Medical Center, Lackland AFB, TX.

925   Profiles and Prognosis of Severe Infantile Atopic Dermatitis with Food Allergy

M. Iguchi ¹, M. Ebisawa², H. Tachimoto²; ¹Jikei University school of Medicine, Tokyo, JAPAN, ²18-1 Sakuradai, Department of pediatrics, National Organization Sagamihra National Hospital, Sagamihara city, Kanagawa, JAPAN.

926   Randomized, Placebo-Controlled Trial of Lactobacillus rhamnosus GG as Treatment of Mild to Moderate Atopic Dermatitis in Infancy

C. Grüber ¹, M. Wendt², S. Lau¹, M. Kulig¹, U. Wahn¹, T. Werfel³, B. Niggemann¹; ¹Dept. of Pediatric Pneumology/Immunology, Charité Universitätsmedizin Berlin, Berlin, GERMANY, ²Department of Dermatology and Allergology, Hanover Medical University, Hanover, GERMANY, ³(2) Department of Dermatology and Allergology, Hanover Medical University, Hanover, GERMANY.

927   Contact Dermatitis to Lanolin Masquerading as Chronic Dyshydrotic Eczema

R. Harris, M. S. Johnson; Allergy and Asthma Associates, Beverly Hills, CA.

Poster Session

4209

Monday, March 06, 2006 9:45 am to 10:45 am

Informatics

928   Evaluating the Internet as a Source of Information about Steroids for Asthma Patients

V. U. Rao, A. J. Apter; Pulmonary, Allergy, and Critical Care, University of Pennsylvania, Philadelphia, PA.

929   Accurate and Effortless Retrieval and Interpretation of Evidence Based Medical Literature

D. Dinakarpandian¹, Y. Lee¹, K. Vishwanath¹, C. Dinakar ²; ¹Computer Science and Electrical Engineering, University of Missouri at Kansas City, Kansas city, MO, ²Section of Allergy, Asthma and Immunology, Children's Mercy Hospital, Kansas city, MO.

930   Utilizing International Resources to Conduct Clinical Trials More Effectively and Efficiently

P. Muniyappa, S. Swami; ExcelTrials, Los Angeles, CA.

931   Young Adult Asthmatics Dissatisfied with Small Hospital Care

J. L. Langager, J. M. Dammann, L. M. Weaver Swartz; Press Ganey Associates, Inc, South Bend, IN.

Poster Session

4211

Monday, March 06, 2006 9:45 am to 10:45 am

T-Cells and Dendritic Cells

932   Foxp3 Tr1 Regulatory T cells as a Therapeutic Antidote in Reversing Cockroach-Induced Asthma

H. S. McGee; Biomedical Science, Creighton University, Omaha, NE.

933   Major Basic Protein Homolog (MBP2): A Specific Human Eosinophil Marker

D. A. Plager ¹, D. A. Loegering¹, J. L. Checkel¹, J. Tang¹, G. M. Kephart¹, P. L. Caffes¹, C. R. Adolphson¹, L. E. Ohnuki², G. J. Gleich²; ¹Mayo Clinic, Rochester, MN, ²University of Utah, Salt Lake City, UT.

934   Plasmacytoid Dendritic Cell Recruitment to Murine Lung During Paramyxoviral Infection is Type I Ifn Receptor Dependent

S. S. Joo, M. M. Rohlfing, M. H. Grayson; Allergy Immunology, Washington University School of Medicine, Saint Louis, MO.

935   Number and Phenotypes of Dendritic Cells in the Bronchial Mucosa of Asthmatics and Controls

A. V. H. Jayaratnam, S. Ying, Q. Meng, C. Corrigan; Department of Asthma, Allergy and Respiratory Sciences, King's College London School of Medicine at Guy's, King's College and St. Thomas's Hospitals, London, UNITED KINGDOM.

936   Toll-like Receptor Agonists and PGE2 Differentially Regulate CysLT1 Receptor Expression and Function in Human Dendritic Cells

M. Rola-Pleszczynski, M. Thivierge, J. Stankova; Immunology Division, Université de Sherbrooke, Sherbrooke, PQ, CANADA.

937   CD8+/BLT1+/IL-13+ T Cells in (Human) Asthma: Is There a Link to Steroid-Resistance

E. W. Gelfand; Department of Pediatrics, National Jewish Medical and Research Centr, Denver, CO.

938   Regulatory Role of CD4⁺CD25⁺ T Cells in the Antigen Specific Induction of Tolerance in a Murine Model of Asthma

C. Boudousquié, C. Longaretti, N. Barbier, F. Spertini; Centre Hospitalier Universitaire Vaudois, LAUSANNE, SWITZERLAND.

939   Cross-Linking FceRIa on a Dendritic Cell Line Induces Increased IFNγ Production from CD8⁺ T Cells

D. S. Cheung, K. M. Shaw, M. M. Rohlfing, M. H. Grayson; Division of Allergy and Immunology, Washington University School of Medicine, Saint Louis, MO.

940   IL-10 Is Essential For Naturally Occurring Lung CD4+CD25+ T Cell Regulation of Allergen-induced Airway Hyperresponsiveness

A. A. Joetham, K. Takeda, M. Shigeki, C. Taube, N. Miyahara, T. Koya, A. Dakhama, E. Gelfand; PEDS, NJC, Denver, CO.

941   Critical Role Of Antigen-Specific Lymphocytes In The Induction Of Asthma Associated Eosinophilic Esophagitis (EE)

A. Mishra, E. Brandt, J. Schlotman, M. E. Rothenberg; Allergy and Immunology, Childrens Hospital Medical Center, Cincinnati, OH 45229, Cincinnati, OH.

942   Regulatory T Cells Protect Against Experimentally-Induced Asthma by Altering the Dendritic Cell Phenotype and Activation State

I. P. Lewkowich, N. S. Herman, K. W. Schleifer, A. A. Sproles, M. Wills-Karp; Immunobiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

943   The Leukotriene B4 Receptor (BLT1) is Required for Effector CD8+ T-Cell-Mediated, Mast Cell-Dependent Airway Hyperresponsiveness

N. Miyahara ¹, C. Taube¹, V. Ott², B. Swanson², K. Takeda¹, S. Miyahara¹, S. Matsubara¹, T. Koya¹, J. Loader¹, L. D. Shultz³, A. M. Tager⁴, A. D. Luster⁴, A. Dakhama¹, E. W. Gelfand¹; ¹Pediatrics, National Jewish Medical and Research Center, denver, CO, ²Immunology, National Jewish Medical and Research Center, denver, CO, ³The Jackson Laboratory, Bar Harbor, MN, ⁴Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Charlestown, MA.

944   Th2 and Th1 Cytokines and Chemokines in Allergen-Challenged Skin Blisters in Atopic Subjects

Y. Ong, A. B. Kay; NHLI Division, Imperial College, London, UNITED KINGDOM.

945   Effect of Nasal Steroid Treatment on Mucosal FOXP3+ Cells in Allergic Rhinitis Patients

C. Malmhäll, A. Bossios, T. Pullerits, J. Lötvall; Lung Pharmacology group, Respiratory Medicine and Allergology, Göteborg University, Gothenburg, SWEDEN.

946   Demethylation of IL-13 and IL-4 Promoter Regions is Associated with Allergen Sensitization and Atopic Asthma

A. M. Schiltz ¹, L. Yan², A. H. Liu^1,3; ¹Pediatric Allergy and Immunology, National Jewish Medical and Research Center, Denver, CO, ²Biosystem Group, Biotage, Inc, Foxboro, MA, ³Pediatrics, University of Colorado School of Medicine, Denver, CO.

947   Novel Ribbon-Type NF-AT Decoy Oligodeoxynucleotides Preclude Th2 Cytokines Expression and Airways Hyperreactivity in Experimental Asthma

Y. Nakamura, K. Yamauchi, H. Inoue; Third Department of Internal Medicine, Iwate Medical University, Morioka, JAPAN.

948   Hydrocortisone Upregulates Th2-type Cytokine and Chemokine Receptor mRNA on Human B-lymphocytes.

S. Al-Tamemi^1,2, H. Zuzan³, A. Norris³, A. Saenz³, A. Ponton³, J. Guay², O. Hajoui², T. Hudson³, B. Mazer ^1,2; ¹Pediatrics, McGill University/Montreal Children's Hosp., Montreal, PQ, CANADA, ²Meakins Christie Laboratories, Montreal, PQ, CANADA, ³McGill University/Genome Quebec Innovation Center, Montreal, PQ, CANADA.

949   Flt3L Treatment Increases Tolerogenic Semimature Dendritic Cells in the Lungs of Asthmatic Mice

A. S. Bharadwaj ¹, D. K. Agrawal²; ¹Medical Microbiology and Immunuology, Creighton University School of Medicine, Omaha, NE, ²Biomedical Sciences, Medicine, Medical Microbiology and Immunology, Creighton University School of Medicine, Omaha, NE.

950   The Role of T Cells in a Murine Model of Contact Hypersensitivity

N. Fyhrquist-Vanni ¹, A. Lauerma², H. Alenius¹; ¹Unit of Excellence in Immunotoxicology, Finnish Institute of Occupational Health, Helsinki, FINLAND, ²Section of Dermatology, Finnish Institute of Occupational Health, Helsinki, FINLAND.

951   Gr-1+ Cells Induce the Expression of Matrix Metalloproteinases (MMPs) that Are Crucial for Antigen-Stimulated Recruitment of Th Cells into Murine Airways

Y. W. Jung ¹, C. L. Zindl¹, C. T. Weaver², D. D. Chaplin¹; ¹Microbiology, University of Alabama at Birmingham, Birmingham, AL, ²Pathology, University of Alabama at Birmingham, Birmingham, AL.

952   Functional and Phenotypic Characterization of CD8+CD28- T Cells in Atopic and Non-Atopic Individuals

O. M. M. Lourenco, A. R. S. Rafael, A. M. L. Fonseca, L. M. P. Taborda-Barata; Department of Medical Sciences, University of Beira Interior, Health Sciences Research Centre, Covilha, PORTUGAL.

953   Inverse Correlation between Circulating CD4⁺CD25^high Cells and CD4⁺IL4⁺ Cells In Vivo

K. Orihara ^1,2, T. Tobe², A. Akasawa³, H. Saito¹, K. Matsumoto¹; ¹Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN, ²Graduate School of Pharmaceutical Sciences, Showa University, Tokyo, JAPAN, ³Department of Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, JAPAN.

954   CD4+CD25++ T Cells in Peripheral Blood Correlate with Total and Pollen-Specific IgE in Young Children

K. A. Burmeister ¹, C. Seroogy², C. Tisler¹, M. Evans³, L. Franco¹, L. Pleiss¹, R. Gangnon³, R. F. Lemanske, Jr.², J. E. Gern²; ¹Dept of Pediatrics, University of Wisconsin-Madison, Madison, WI, ²Dept of Medicine, University of Wisconsin-Madison, Madison, WI, ³Dept of Biostatistics and Medical Informatics and Population Health Sciences, University of Wisconsin-Madison, Madison, WI.

955   Expression of Polarized T-Cell Surface Markers in Respiratory Allergy

U. De Fanis, F. Mori, S. L. Limb, R. G. Hamilton, N. F. Adkinson, Jr., V. Casolaro; Johns Hopkins University, Baltimore, MD.

956   Monitoring the T Cell Response in a Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) to Phenytoin in both Peripheral Blood and Skin

J. A. Cornejo-Garcia¹, E. Martin², T. D. Fernandez¹, C. Mayorga¹, S. Lopez¹, R. R-Pena¹, I. Doña², J. L. Rodriguez-Bada¹, M. Blanca ²; ¹Research Laboratory, Carlos Haya Hospital, Malaga, SPAIN, ²Allergy Service, Carlos Haya Hospital, Malaga, SPAIN.

957   Non-Immediate Reaction to Iodine Contrast Media

E. Martin ¹, J. A. Cornejo-Garcia², R. R-Pena², T. D. Fernandez², S. Lopez², C. Mayorga², M. J. Torres¹, C. Antunez², M. Valenzuela¹, M. Blanca¹; ¹Allergy Service, Carlos Haya Hospital, Malaga, SPAIN, ²Research Laboratory, Carlos Haya Hospital, Malaga, SPAIN.

958   Tolerance Induction Via the Nasal Route is Associated with Downregulation of Lung Cytokine Production, Including Il-10, in a Mouse Model of Asthma

C. Longaretti, C. Boudousquié, F. Spertini; Laboratoire d'Immunologie et Allergie, CHUV, Lausanne, SWITZERLAND.

Poster Session

4212

Monday, March 06, 2006 9:45 am to 10:45 am

Cytokines, Chemokines and Receptors

959   In Vitro and in Vivo Effects of IL-10-Treated Dendritic Cells on Airway Allergic Inflammation

T. Koya, K. Takeda, S. Matsubara, N. Miyahara, S. Miyahara, C. Swasey, A. Barhorn, A. Joetham, A. Dakhama, E. W. Gelfand; Division of Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO.

960   Prenatal Exposure with Aerosolized Allergen Prevents Subsequent Allergen-Induced Sensitization and Airway Inflammation in Young Mice

K. Gerhold, A. Avagyan, C. Seib, B. Ahrens, J. Jaworska, A. Dittrich, U. Wahn, E. Hamelmann; Department of Pediatric Pulmology and Immunology, Charité, Campus Virchow-Clinic, Berlin, GERMANY.

961   IL-13 Receptors in the Skin

M. R. Warrier, Y. Tabata, M. O. Daines, W. Chen, G. K. Khurana Hershey; Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

962   Gene-gene Interaction Between IL-13 and IL-13Ra1 Polymorphisms is Associated with Total IgE in Korean Children with Atopic Asthma

H. Kim ¹, S. Lee², J. Kim¹, B. Kim¹, M. Kang³, S. Jang³, S. Hong¹; ¹Pediatrics, Asan Medical Center, Seoul, REPUBLIC OF KOREA, ²Pediatrics, Hallym Medical Center, Seoul, REPUBLIC OF KOREA, ³Pediatrics, Asan Institute for Life Science, Seoul, REPUBLIC OF KOREA.

963   Combination of Interleukin (IL)-2 and IL-18 Attenuates Allergen-Induced Airway Hyperresponsiveness (AHR) and Inflammation through An IL-12-STAT4-Interferon (IFN)-gamma Pathway

S. Matsubara, K. Takeda, T. Kodama, T. Koya, N. Miyahara, A. Joetham, C. H. Swasey, A. Dakhama, E. W. Gelfand; Division of Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, CO.

964   Activating Signals from the IL-5 Receptor Simultaneously Initiate a Termination Pathway

M. M. Gorska ¹, O. Cen², S. J. Stafford², Q. Liang¹, R. Alam¹; ¹Medicine, National Jewish Medical and Research Center, Denver, CO, ²Medicine, University of Texas Medical Branch, Galveston, TX.

965   Hepatitis B Core Antigen (HBcAg) Particles Carrying Interleukin (IL)-4 Epitopes Break Immune Tolerance and Down-regulate Murine Allergic Airway Responses

S. Ying ¹, Y. Ma¹, K. T. HayGlass^2,1, G. Srinivasan¹, Y. Fan³, X. Yang^3,2, A. B. Becker^1,2, F. E. R. Simons^1,2, Z. Peng^1,2; ¹Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, CANADA, ²Immunology, University of Manitoba, Winnipeg, MB, CANADA, ³Medical Microbiology, University of Manitoba, Winnipeg, MB, CANADA.

966   Nerve Growth Factor Regulates the Production of Lung Mucins in a Transgenic Mice Model of Asthma

A. Micera ¹, C. Hahn², A. Lambiase¹, A. Nockher², G. Rasi³, S. Bonini¹, H. Renz², S. Bonini³; ¹Dept Ophthalmology, Campus Biomedico and G.B. Bietti Eye Foundation, IRCCS, Rome, ITALY, ²Dept of Clinical Chemistry and Molecular Diagnostics, Faculty of Medicine, Philippe University, Marburg, GERMANY, ³INMM-CNR and IRCCS San Raffaele, Rome, ITALY.

967   NNY-CCL14 Acts on Diverse CC Chemokine Receptors and Prevents Airway Hyperresponsiveness

S. Gupta ¹, U. Forssmann², S. Schulz-Maronde¹, B. Fuchs³, A. Braun³, W. G. Forssmann¹, J. Elsner⁴; ¹Dept. of Pharmacology & Toxicology, Hannover Medical School, Hannover, GERMANY, ²IPF PharmaCeuticals GmbH, Affiliated Institute of Hannover Medical School, Hannover, GERMANY, ³Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, GERMANY, ⁴Department of Dermatology and Allergology, Fachklinik Bad Bentheim, Bad Bentheim, GERMANY.

968   The Relationship between Childhood Wheezing and Overweight Status as a Function of the Proinflammatory Mediators IL-6 and Leptin in a High-Risk Birth Cohort

S. L. Friedlander ¹, D. J. Mueller², Z. Zhang³, K. A. Roberg², E. L. Anderson², M. D. Evans⁴, R. E. Gangnon⁵, H. J. Lai³, J. E. Gern⁶, R. F. Lemanske, Jr.⁶; ¹Medicine, University of Wisconsin at Madison, Madison, WI, ²Pediatrics, University of Wisconsin at Madison, Madison, WI, ³Nutritional Sciences, University of Wisconsin at Madison, Madison, WI, ⁴Biostatistics and Medical Informatics, University of Wisconsin at Madison, Madison, WI, ⁵Biostatistics and Medical Informatics; Population Health Sciences, University of Wisconsin at Madison, Madison, WI, ⁶Pediatrics and Medicine, University of Wisconsin at Madison, Madison, WI.

969   Novel Interleukin-13 Peptide-based Vaccine Downregulates Murine Allergic Airway Responses

Z. Peng ¹, Y. Ma¹, Y. Fan², G. Srinivasan¹, X. Yang², A. Becker¹, F. E. R. Simons¹, K. T. HayGlass³; ¹Pediatrics and Child Health, University of Manitoba, Winnipeg, Manitoba, MB, CANADA, ²Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, MB, CANADA, ³Immunology, University of Manitoba, Winnipeg, Manitoba, MB, CANADA.

970   Transforming Growth Factor-Beta 2 (TGF-b2) is Expressed in the Remodeled Airways of Mice with Allergic Asthma

A. V. Le ¹, J. Y. Cho², M. Miller², D. H. Broide²; ¹Allergy & Immunology, Scripps Clinic, La Jolla, CA, ²Allergy & Immunology, UCSD, La Jolla, CA.

971   DA-9601 Reduces Inflammatory Respopnses in OVA-Specific Allergic Asthma in Mice

J. Ro ^1,2, J. Kim^1,2, S. Ryu^1,2, B. Lee³; ¹Department of Pharmacology, Sungkyunkwan University School of Medicine, Suwon, REPUBLIC OF KOREA, ²Center for Molecular Medicine, Samsung Biomedical Research Institute, Suwon, REPUBLIC OF KOREA, ³Department of Microbiology, College of Medicine Yonsei University, Seoul, REPUBLIC OF KOREA.

972   Pro-Angiogenic Activity is Increased in Bronchoalveolar Lavage Fluid (BALf) from Asthmatics

D. E. Simcock, G. W. Clarke, V. Kanabar, S. D. Greenaway, S. J. Hirst, B. J. O'Connor; Asthma, Allergy and Respiratory Science, King's College School of Medicine, London, UNITED KINGDOM.

973   Th1 and Th2 Cytokine-mediated CXC Chemokine Production in Human Lung Microvascular Endothelial Cells in Vitro

A. Matsuda, H. Saito, K. Matsumoto; Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN.

974   Differential IL-2-Induced Accumulation of IL-13⁺ and IFN-Gamma⁺ Peripheral Blood T Cells (PBL) between Asthmatic and Non-Asthmatic Subjects

M. J. Loza, S. Foster, S. P. Peters, R. B. Penn; Internal Medicine/Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, NC.

975   Regulation Of IL-5Ra On Bone Marrow Eosinophils and CD34⁺ Progenitors

L. D. Saleh, G. M. Gauvreau, M. Duong, K. Howie, A. Cordova, R. Sung, T. Rerecich, P. M. O'Byrne; McMaster University, Hamilton, ON, CANADA.

976   Brain Derived Neurotrophic Factor (BDNF), B-Lymphocyte Chemoattractant (CXCL13), and Macrophage Inhibitory Protein 3α (MIP-3α) are Increased in Sputum of Severe and Nonsevere Asthmatics with Elevated Neutrophil Percentages

A. T. Hastie, W. C. Moore, J. Krings, R. Smith, P. Vestal, M. Wu, D. A. Meyers, S. P. Peters, E. Bleecker; Center for Human Genomics, Wake Forest University School of Medicine, Winston-Salem, NC.

977   Nasal Fibroblasts Derived from Allergic Patients Retain Their Typical Gene Expression Profile in Culture

M. Yoshikawa ¹, K. Wada¹, N. Otori¹, S. Haruna¹, N. Okada², H. Saito², H. Moriyama¹; ¹Department of Otorhinolaryngology, Jikei University School of Medicine, Tokyo, JAPAN, ²Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN.

978   Epigenetic Maintenance of Immunological Responses in Asthma

R. Su ¹, A. Becker^1,2, A. L. Kozyrskyj^2,3, K. T. HayGlass^1,2; ¹CIHR National Training Program in Allergy and Asthma Research, Immunology, University of Manitoba, Winnipeg, MB, CANADA, ²Community Health Sciences, Winnipeg, MB, CANADA, ³Pediatrics/Child Health, Winnipeg, MB, CANADA.

979   Diesel Exposure Favors Th2 Cell Recruitment by Mononuclear Cells from Nonatopic Subjects by Differentially Regulating CCL18/PARC and CXCL10/IP-10 Production

Y. CHANG ^1,2, S. SENECHAL¹, P. de NADAI¹, C. CHENIVESSE^1,3, J. GILET¹, H. VORNG¹, A. TONNEL^1,3, B. WALLAERT^1,3, A. TSICOPOULOS^1,3; ¹INSERM U-416, Institut Pasteur de Lille, Lille, FRANCE, ²Department of Central Research, The Third Clinical College, Jilin University, Chang Chun, CHINA, ³Clinique des Maladies Respiratoires et Centre Hospitalier Régional et Universitaire de Lille, Lille, FRANCE.

980   Transgenic Mice Overexpressing Human IL-17E Exhibit an Asthma-Like Phenotype that is Exacerbated in an Ovalbumin-Induced Model of Asthma

A. L. Budelsky, L. A. Steffen; Inflammation Research, Amgen, Seattle, WA.

981   Allergic Cytokines Regulate Expression of Glucocorticoid Receptor [GR] Alpha and Beta Isoforms

J. L. Rabbitt, W. J. Calhoun; Allergy, Pulmonary, Immunology, CCM, and Sleep, University of Texas Medical Branch, Galveston, TX.

982   The Role of Cytokines in Allergic Inflammation in Human Lung Tissue

L. R. C. Barnicott, T. Hackett, J. A. Warner; School of Biological Sciences, University of Southampton, Southampton, UNITED KINGDOM.

983   Involvement of TRAIL in Transforming Growth Factor-Beta-Induced Apoptosis of Human Airway Epithelial Cells

B. Chaudhari, G. Cheng, D. Agrawal; Biomedical Science, Creighton University School of Medicine, Omaha, NE.

984   Mold Allergen, Pen C 13, Induce Inflammatory Cytokines in Human Bronchial Epithelial Cells via Activation of Protease-Activated Receptor

L. Chow ¹, L. Chiu¹, C. Yu¹, S. Su²; ¹Institute of Biochemistry and Molecular Biology, College of Medicine, National Taiwan Univ., Taipei, TAIWAN REPUBLIC OF CHINA, ²Department of Medical Research and Education, Veterans General Hospital-Taipei, Taipei, TAIWAN REPUBLIC OF CHINA.

985   Inflammatory Cytokines in Lung Lavage Fluid Determined by Bead-Based and ELISA Cytokine Assays

K. Kulhankova, S. Hadina, P. S. Thorne; Occupational & Environmental Health, University of Iowa, College of Public Health, Iowa City, IA.

986   Expression of IL-13 Receptors in Human Airway and Skin Cells

Y. Tabata, M. R. Warrier, M. O. Daines, W. Chen, G. K. Khurana Hershey; Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

987   Newly Produced CD4+ Cells in Bone Marrow after Airway Allergen Exposure

A. Bossios, C. Malmhäll, M. Rådinger, L. Mannerås, L. Petersson, M. Sjöstrand, J. Lötvall; The Lung Pharmacology Group, Department of Respiratory & Allergology, Göteborg University, Gothenburg, SWEDEN.

988   Effect of Prolonged Budesonide Therapy on IL-4, IL-5, and IL-10 in a Murine Model of Asthma

K. S. Konduri ¹, S. D. Nandedkar¹, S. Deenamsetty¹, D. A. Rickaby², N. Duzgunes³; ¹Pediatrics, Medical College of Wisconsin, Milwaukee, WI, ²Physiology, Zablocki VA Medical Center, Milwaukee, WI, ³Microbiology, University of Pacific School of Dentistry, San Franscisco, CA.

989   Signal Pathway of Eotaxin Production by Human Nasal Fibroblast

S. Fujieda, N. Takahashi, T. Yamada; Otorhinolaryngology, University of Fukui, Fukui, JAPAN.

990   Anti-inflammatory Mechanism of Simvastatin in OVA-specific Mouse Allergic Asthma

J. Ro ^1,2, J. Kim^1,2, S. Ryu^1,2; ¹Department of Pharmacology, Sungkyunkwan University School of Medicine, Suwon, REPUBLIC OF KOREA, ²Center for Molecular Medicine, Samsung Biomedical Research Institute, Suwon, REPUBLIC OF KOREA.

991   Cytokine Responses to Allergens during the First Two Years of Life in Estonian and Swedish Children

M. C. Jenmalm ¹, M. F. Böttcher¹, T. Voor², K. Julge², P. G. Holt³, B. Björkstén⁴; ¹Department of Molecular and Clinical Medicine, Faculty of Health Sciences, Linköping University, Linköping, SWEDEN, ²Children's Clinic, Tartu University Clinic, Tartu, ESTONIA, ³Telethon Institute for Child Health Research, University of Western Australia, Perth, AUSTRALIA, ⁴Institute of Environmental Medicine, Karolinska Institute, Stockholm, SWEDEN.

992   Regulation of osteopontin by IL-10 and Th2 cytokines in human monocytes and monocyte-derived dendritic cells

S. Konno ¹, N. Hizawa¹, J. A. Eckman², B. Plunkett², D. B. K. Golden², J. Schroeder², M. Nishimura¹, S. Huang²; ¹1st department of Medicine, Hokkaido University, Sapporo, JAPAN, ²Johns Hopkins Asthma Allergy Center, Baltimore, MD.

993   SERUM INTERLEUKIN-7 LEVELS IN PATIENTS WITH ALLERGIC ASTHMA Keskin GOKSAL*, Inal ALI, Musabak UGUR, Sengul ALI *Ankara Etlik Ihtisas Hospital, Immunology Department GATA Immunology Department

A. I^.nal; Gülhane Military Medicine Academy, Ankara, TURKEY.

994   Correlation of IL-18, TARC, LTB4 and LTC4D4E4 and Lung Function in Childhood Asthma

R. Y. T. Sung ¹, Y. O. Wong¹, C. K. Wong¹, T. F. Leung¹, A. M. Li¹, K. L. Cheung¹, K. P. Fung², P. C. Leung², T. F. Fok¹, P. C. Ng¹; ¹Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, HONG KONG SPECIAL ADMINISTRATIVE REGION OF CHINA, ²Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, HONG KONG SPECIAL ADMINISTRATIVE REGION OF CHINA.

995   Association Between Secondhand Smoke Exposure (SSE) and Increased IL-13 Production from CD4+ Cells During Early Childhood

D. Gentile, J. Koehrsen, A. Patel, D. P. Skoner; Department of Pediatrics, Allegheny General Hospital, Pittsburgh, PA.

996   sICAM-1 and IL-8 Levels of Bronchoalveolar Lavage Fluid from Patients undergoing Open-Heart Surgery

Z. Chen, J. Li; Children's Hospital, Medical School of Zhejiang University, Hangzhou, Zhejiang Province, CHINA.

997   Skin Test Reactivity of Asthmatic Patients Associated with Exhaled Breath Condensate IFN-gamma Levels

D. M. Laber, W. C. Moore, A. MacDowell, J. Krings, R. Smith, A. T. Hastie, S. P. Peters, D. Meyers, E. Bleecker; Internal Medicine, Wake Forest University, Winston-Salem, NC.

998   Leukotriene D₄-Induced Transforming Growth Factor β1 in Bronchial Smooth Muscle Cell Proliferation

Y. Bossé, C. Thompson, S. McMahon, C. Dubois, J. Stankova, M. Rola-Pleszczynski; Pediatrics, Université de Sherbrooke, Sherbrooke, PQ, CANADA.

999   ICAM-1 and TNF-a in Patients with Persistent Asthma - Relationship with the Disease Severity

M. Gorska-Ciebiada ¹, M. Ciebiada¹, P. Gorski¹, I. Grzelewska-Rzymowska²; ¹Dept.Pneumology & Allergy, Medical University, Lodz, POLAND, ²Dept.Cancer and Chest Diseases, Medical University, Lodz, POLAND.

1000   Comparative Effects of Organic and Inorganic Mercury Compounds on Human Cytokines Production

E. Jerschow, G. de Vos, S. Abotaga, D. Rosenstreich; Allergy/Immunology Division, Albert Einstein College of Medicine, Bronx, NY.

1001   Responses to Methacholine, Histamine and Osmotic Stimuli after Treatment with Interleukin-13 or Propranolol in Balb/c Versus CFW Mice

N. Qutna, R. Townley; Dept of Medicine - Allergy Division, Creighton University Allergy, Omaha, NE.

1002   The Effect of Smoking on the Expression of Various Cytokines in the Peripheral Blood Mononuclear Cells from Patients with Asthma and COPD

Y. Cho ¹, E. Chun¹, C. Park¹, J. Lee¹, S. Woo²; ¹Internal Medicine, Ewha Womans University, Seoul, REPUBLIC OF KOREA, ²Micobiology, Ewha Womans University, Seoul, REPUBLIC OF KOREA.

Poster Session

4213

Monday, March 06, 2006 9:45 am to 10:45 am

Rhinosinsiusitis Treatment

1003   Effects of Coadministration of Intranasal Ciclesonide (CIC) and Inhaled Beclomethasone Dipropionate (BDP) on Cortisol Suppression

P. H. Ratner ¹, M. A. Wingertzahn², N. Hall², P. Darken², T. Shah²; ¹Sylvana Research Associates, San Antonio, TX, ²Altana Pharma, Florham Park, NJ.

1004   Efficacy and Safety of Ciclesonide (CIC) for the Treatment of Perennial Allergic Rhinitis (PAR)

E. O. Meltzer ¹, S. Kunjibettu², N. Hall², W. Berger³, C. LaForce⁴; ¹Allergy & Asthma Medical Group & Research Center, San Diego, CA, ²Altana Pharma, Florham Park, NJ, ³Allergy and Asthma Associates, Mission Viejo, CA, ⁴Clinical Professor of Pediatrics, University of North Carolina School of Medicine, Raleigh, NC.

1005   Nighttime Symptoms Score Provides Clinically Relevant Measure of Allergic Rhinitis Burden

N. C. Santanello; Merck Research Labs, Merck & Co. Inc, Blue Bell, PA.

1006   Intranasal Phototherapy is an Effective Treatment in Allergic Rhinitis

A. I. Koreck, A. S. Kenderessy, L. Kemeny; Department of Dermatology and Allergology, University of Szeged, Szeged, HUNGARY.

1007   Effect of Levalbuterol on Nasal Mucociliary Transport (MCT) in Healthy Adult Subjects

J. Koehrsen, D. A. Gentile, D. P. Skoner; Department of Pediatrics, Allegheny General Hospital, Pittsburgh, PA.

1008   Persistence and Effusion Clearance to Esophagus of Ciclesonide in Hypotonic and Isotonic Suspensions

M. A. Wingertzahn¹, K. Takanashi ^2,3, A. Nagano^2,3, Y. Namiki^2,3, K. Sakon^2,3, Y. Makino²; ¹Altana Pharma, Florham Park, NJ, ²Teijin Institute for Bio-Medical Research, Tokyo, JAPAN, ³Teijin Pharma Limited, Tokyo, JAPAN.

1009   Benzalkonium Chloride Containing Saline Impairs Nasal Mucociliary Clearance. A Double Blind, Cross-over, Randomized Study

J. Â. Rizzo, A. R. Silva, D. Medeiros, M. Mota, E. S. C. Sarinho; Pediatrics Dept., Universidade Federal de Pernambuco, Recife-PE, BRAZIL.

1010   Intranasal, Non-Inhaled CO2 Provides Rapid Relief of Seasonal Allergic Rhinitis (SAR) Nasal Symptoms

T. B. Casale, F. A. Romero, L. Mahon, A. Bewtra, J. Stokes, R. Hopp; Department of Medicine: Division of Allgery and Immunology, Creighton University, Omaha, NE.

1011   Changes in Urinary Leukotriene E4 Concentration after Sinus Treatment (Surgery or Corticosteroid Therapy) in Patients with Aspirin-Intolerant Asthma

E. Ono, M. Taniguchi, N. Higashi, H. Yamamoto, A. Higashi, C. Oshikata, T. Tsuburai, Y. Maeda, A. Mori, T. Ishii, H. Mita, K. Akiyama; Asthma reseach devision, National Sagamihara Hospital, Sagamihara, JAPAN.

1012   Response to a Standardised Management Strategy for Refractory Chronic Rhinosinusitis: Implications for Studies of Genetics

H. Al-Shemari, M. Cabaluna, M. Duval, S. Sidani, S. Frenkiel, M. Y. Desrosiers; Otorhinolaryngology, McGill University MUHC, Montreal, PQ, CANADA.

1013   Montelukast Augments Bacterial Sinusitis in Allergic Mice

R. M. Naclerio ¹, P. Khoury¹, F. M. Baroody¹, J. J. Klemens¹, K. Thompson²; ¹Otolaryngology-Head and Neck Surgery, University of Chicago, Chicago, IL, ²Pathology, University of Chicago, Chicago, IL.

1014   Drowsiness and Sedation: A Comparison Between Levocetirizine and Desloratadine Using Post-Marketing Observational Data

D. Layton ^1,2, L. W. Wilton^1,2, A. Boshier^1,2, V. Cornelius¹, S. Harris³, S. A. W. Shakir^1,2; ¹Drug Safety Research Unit, Southampton, UNITED KINGDOM, ²Faculty of Science, University of Portsmouth, Portsmouth, UNITED KINGDOM, ³Public Health Sciences & Medical Statistics, Southampton University Hospital Trust, Southampton, UNITED KINGDOM.

1015   Sinus and Mastoid Involvement in Cystic Fibrosis and the Efficacy of Surgical Intervention

A. A. Horwitz ¹, G. Graff¹, R. Vender¹, L. Sachs², T. Craig¹; ¹Hershey Medical Center, Hershey, PA, ²Harrisburg Hospital, Harrisburg, PA.

1016   Radiofrequency for the Treatment of Allergic Rhinitis Refractory to Medical Therapy

D. Matesic ¹, J. B. Bitner², R. O. Gustafson², J. F. Pallanch²; ¹Allergic Diseases, Mayo Clinic and Foundation, Rochester, MN, ²Otolaryngology, Mayo Clinic and Foundation, Rochester, MN.

1017   Azelastine Nasal Spray and Fluticasone Nasal Spray in the Treatment of Geriatric Patients with Rhinitis

V. B. Behncke¹, G. Alemar², D. A. Kaufman¹, F. J. Eidelman ¹; ¹Allergy and Immunology, Cleveland Clinic Florida, Weston, FL, ²Otorhinolaryngology, Cleveland Clinic Florida, Weston, FL.

Poster Session

4214

Monday, March 06, 2006 9:45 am to 10:45 am

Immunotherapy Immunological and Objective Measures

1018   Change In Plasma C5a Levels After Routine Allergen Immunotherapy Correlates With Dust Mite Dosage, Changes in Wheal Size, And Rhinoconjunctivitis Symptoms

C. Charlot, C. Bowser, H. Drew, R. Feliz, M. Nowakowski, R. Joks; Center for Allergy and Asthma Research, SUNY-HSC, Brooklyn, NY.

1019   Screening for Cellular Changes During Grass-Specific Subcutaneous Immunotherapy

A. H. Millner ¹, G. Lund¹, J. Francis², S. Durham², K. Lund¹, P. A. Würtzen¹; ¹Research, ALK-Abelló, Hørsholm, DENMARK, ²Upper Respiratory Medicine, National Heart and Lung Institute, Imperial College, London, UNITED KINGDOM.

1020   Cytokine and Chemokine Gene Expression Monitoring in a Ragweed Allergy Clinical Trial with Omalizumab Pre-Treatment

V. Seyfert-Margolis ¹, T. B. Casale², A. Asare¹, R. S. Wang¹; ¹Tolerance Assay and Data Analysis, UCSF - Immune Tolerance Network, Bethesda, MD, ²Medicine, Creighton University, Omaha, NE.

1021   Induction of a Competitive Non-IgE Antibody Response by Specific Immunotherapy is Related to Clinical Efficacy

C. Ljørring ¹, A. J. Frew², S. R. Durham³, L. Jacobsen¹, N. Johansen¹, J. N. Larsen¹, H. Ipsen¹; ¹ALK-Abelló, Hørsholm, DENMARK, ²Infection, Inflammation and Repair Division, Southampton General Hospital, Southampton, UNITED KINGDOM, ³Upper Respiratory Medicine, National Heart and Lung Institute, London, UNITED KINGDOM.

1022   Induction of Regulatory T Cells with Sublingual Allergy Vaccines

P. E. MOINGEON, L. VAN OVERTVELT, A. RAZAFINDRATSITA, L. MASCARELL, E. WAMBRE, V. LOMBARDI, N. SAINT-LU; R&D, Stallergenes SA, Antony, FRANCE.

1023   The Comparison of Influence of Two Different Application Forms of Grass Pollen Immunotherapy- the Changes on the Level of Cytokines Il-4 and Ifn Gamma After 24 Months of Immunotherapy

I. Krcmova, C. Andrys; of Clinical Immunology and Allergy, Faculty Hospital Charles University, Hradec Kralove, CZECH REPUBLIC.

1024   Safety of Allergenic Immunotherapy in Systemic Lupus Erythematosus

A. Fiorillo, L. Fonacier, C. Diola; Allergy and Immunology, Winthrop University Hospital, Mineola, NY.

Oral Abstract Session

4601

Monday, March 06, 2006 2:00 pm to 3:15 pm

Adherence and Health Care Delivery

1025   Prescription Fill Patterns in Underserved Children with Asthma

M. E. Bollinger ¹, A. Boldt¹, K. E. Mudd¹, A. Manning², V. D. Hsu³, M. G. Tsoukleris³, A. M. Butz²; ¹Pediatrics, University of Maryland School of Medicine, Baltimore, MD, ²Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, ³University of Maryland School of Pharmacy, Baltimore, MD.

1026   Objective Measurement of Adherence with Asthma Medications

B. Bender ¹, S. Bartlett², C. Rand², C. Turner³, F. Wamboldt¹, L. Zhang¹; ¹National Jewish Medical and Research Center, Denver, CO, ²Johns Hopkins University, Baltimore, MD, ³Research Triangle Institute, Research Triangle Park, NC.

1027   Adherence with Treatment Guidelines in Mild Asthma Patients: Clinical Outcomes Associated with Fluticasone Propionate/salmeterol Vs. Inhaled Corticosteroid Therapy

C. Carter¹, S. Sison¹, B. Yawn², H. M. Harris ¹, D. Ollendorf¹; ¹PharMetrics, Inc., Watertown, MA, ²Olmsted Medical Center, Rochester, MN.

1028   Asthma Control: Associations with Patient Characteristics, Severity, Exacerbations, Quality of Life and Feno at an Specialized Outpatient Clinic

J. A. Fonseca ^1,2, L. Fernandes³, A. Costa-pereira¹, L. Delgado^4,2, S. Martins², A. Moreira^4,2, M. Vaz², M. Castel-Branco²; ¹Bioestatistica e Informatica Medica, Faculdade Medicina Universidade do Porto, Porto, PORTUGAL, ²Imunoalergologia, Hospital S. Joao, Porto, PORTUGAL, ³Psiquiatria, Faculdade Medicina Universidade do Porto, Porto, PORTUGAL, ⁴Imunologia, Faculdade Medicina Universidade do Porto, Porto, PORTUGAL.

Oral Abstract Session

4602

Monday, March 06, 2006 2:00 pm to 3:15 pm

Therapeutic Targeting of Cell Adhesion and Migration

1029   Both α4 And β2 Integrins Regulate Acute Allergic Asthma but by Different Pathways

E. Ray Banerjee ¹, W. R. Henderson, Jr.¹, T. Papayannopoulou²; ¹Medicine, Allergy and Inflammation, University of Washington, Seattle, WA, ²Medicine, Hematology, University of Washington, Seattle, WA.

1030   Critical Evaluation of Adhesion Molecule Targeting Therapy in Murine Models of Multiple Sclerosis

S. M. Kerfoot ^1,2, M. U. Norman², P. Kubes²; ¹Yale University School of Medicine, New Haven, CT, ²University of Calgary, Calgary, AB, CANADA.

1031   CX₃CR1 Deficiency Results in Diminished Vascular Inflammation

P. Liu ¹, S. Patil¹, M. Rojas², A. M. Fong¹, S. S. Smyth², D. D. Patel¹; ¹Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Carolina Cardiovascular Biology Center, University of North Carolina at Chapel Hill, Chapel Hill, NC.

1032   CCR5 Usage by CCL5 Induces a Selective Leukocyte Recruitment in Human Skin Xenografts in Vivo

A. Tsicopoulos ¹, P. de Nadai¹, C. Chenivesse¹, H. Porte², H. Vorng¹, A. F. Walls³, B. Wallaert¹, A. Tonnel¹, H. Zerwes⁴; ¹Institut Pasteur de Lille, U416 INSERM, Lille cedex, FRANCE, ²Service de Chirurgie, CHRU de Lille, Lille cedex, FRANCE, ³Immunopharmacology group, Southampton general hospital, Southampton, UNITED KINGDOM, ⁴Novartis, basel, SWITZERLAND.

Oral Abstract Session

4603

Monday, March 06, 2006 2:00 pm to 3:15 pm

Occupational Asthma: New Insights Into Risk Factors and Pathogenesis

1033   Immunologic Changes in Human Albumin Exposed to Toluene Diisocyanate (TDI) Vapor: Differences Compared with Liquid TDI Exposure and Association with IgE/IgG Binding and TDI Asthma

Y. Ye ¹, S. Kim², S. Lee, III³, H. Park¹, C. A. Redlich⁴, A. V. Wisnewski⁴; ¹Dept. of Allergy & Rheumatology, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA, ²Dept. of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, REPUBLIC OF KOREA, ³Donga University School of Medicine, Busan, REPUBLIC OF KOREA, ⁴Yale University School of Medicine, New Haven, CT.

1034   Prediction of Specific Airway Responsiveness from Skin Sensitivity to Allergen and Airway Hyperresponsiveness to Methacholine in Baker's Asthma

S. Quirce, M. Fernández-Nieto, C. Escudero, J. Cuesta, M. de las Heras, J. Sastre; Allergy Department, Fundación Jiménez Díaz, Madrid, SPAIN.

1035   Evaluation of Eosinophilic Inflammation in Patients with Suspected Occupational Asthma or Rhinitis

G. Moscato, M. Yacoub, D. Moretto, L. Perfetti, M. Pozzoni, P. Pignatti; Allergy and Immunology Unit, Fondazione Salvatore Maugeri, IRCCS, Pavia, ITALY.

1036   Hexamethylene Diisocyanate Exposed Workers Are Less Likely to Have Confirmed Occupational Asthma than Workers Exposed to Other Isocyanates

A. M. Smith ¹, P. Campo¹, Z. L. Lummus¹, A. Cartier², J. Malo², L. Boulet³, D. I. Bernstein¹; ¹Division of Immunology, University of Cincinnati, Cincinnati, OH, ²Hôpital du Sacré Coeur de Montréal, Montreal, PQ, CANADA, ³Hôpital Laval, Laval, PQ, CANADA.

Oral Abstract Session

4604

Monday, March 06, 2006 2:00 pm to 3:15 pm

Cutaneous Inflammation

1037   Glucocorticoid-Induced TNF-Receptor Related Ligand (GITR-L) is Increased in Atopic Dermatitis (AD) Skin

I. D. Cardona ¹, E. Goleva¹, M. D. Howell¹, L. S. Ou², M. Boguniewicz¹, D. Y. Leung¹; ¹Pediatrics, National Jewish Med. and Research Center, Denver, CO, ²Pediatrics, Chang Gung Children's Hospital, Taoyuan, TAIWAN REPUBLIC OF CHINA.

1038   Delineation of IL-13 Functions in Allergic Eczematous Skin Diseases

R. Purwar, T. Werfel, M. Wittmann; Dermatology & Allergology, Hannover Medical School, Hannover, GERMANY.

1039   Co-Signalling Molecules (B7 homologs) are Expressed by Human Keratinocytes

A. De Benedetto ¹, A. C. Myers², L. McGirt¹, L. Chen³, M. Brummet¹, R. P. Schleimer⁴, L. A. Beck¹; ¹Division of Allergy and Clinical Immunology, Johns Hopkins, Baltimore, MD, ²Clinical Immunology, Johns Hopkins, Baltimore, MD, ³Department of dermatology, Johns Hopkins, Baltimore, MD, ⁴Allergy-Immunology Division, Northwestern University Feinberg, Chicago, IL.

1040   Eosinophils Produce an Innate Immune Response to Staphylococcus Aureus through Recognition of Peptidoglycan

A. Terada ¹, H. Kita²; ¹Pediatric Allergy, Daido Hospital, Nagoya, JAPAN, ²Medicine and Immunology, Mayo Clinic, Rochester, MN.

Oral Abstract Session

4605

Monday, March 06, 2006 2:00 pm to 3:15 pm

Quality of Life

1041   A Study to Assess the Quality of Life in Children with Peanut Allergy, their Parents and Siblings

R. M. King ¹, R. C. Knibb², J. O. Hourihane³; ¹Wellcome Trust Clinical Research Facility, Southampton University Hospitals NHS Trust, UNITED KINGDOM, ²School of Social Sciences, University of Derby, UNITED KINGDOM, ³Dept Child Health, University College Cork, IRELAND.

1042   Development of a Disease Specific Health-related Quality of Life (HRQOL) Questionnaire in Adults with Hereditary Angioedema due to C1 inhibitor Deficiency (HAE) in Spain (First Phase)

N. Prior ¹, E. Remor², C. López Serrano³, T. González⁴, S. Cimbollek⁴, M. Guilarte⁵, D. Hernandez⁶, M. Tejedor⁷, M. Rubio⁸, T. Caballero³; ¹Allergy Department, Hospital Universitario, Madrid, SPAIN, ²Faculty of Psychology, Autonoma University, Madrid, SPAIN, ³Allergy Department, Hospital Universitario “La Paz”, Madrid, SPAIN, ⁴Allergy Department, Hospital Universitario “Virgen del Rocío”, Seville, SPAIN, ⁵Allergy Department, Hospital Universitario “Vall D´Hebrón”, Barcelona, SPAIN, ⁶Allergy Department, Hospital Universitario “La Fe”, Valencia, SPAIN, ⁷Allergy Department, Fundación Hospital Alcorcón, Madrid, SPAIN, ⁸Allergy Department, Hospital Universitario “Gregorio Marañón”, Madrid, SPAIN.

1043   The Impact of Asthma on Quality-of-Life (QoL) and Other Patient-Reported Outcomes: The Patient's Perspective

S. P. McKenna ¹, D. M. Meads¹, K. M. Beusterien², R. Flood², H. Lau³, A. Glendenning⁴; ¹Galen Research, Manchester, UNITED KINGDOM, ²MEDTAP International, Bethesda, MD, ³Novartis Pharmaceuticals, East Hanover, NJ, ⁴Novartis Horsham Research Centre, Horsham, UNITED KINGDOM.

1044   Factors that Influence Quality of Life (QOL) in Rural Families with Asthma

J. M. Walker ¹, L. Lewis-Boyer², K. Hill², C. Lewis¹, L. Pham³, A. Butz¹; ¹Pediatrics, Johns Hopkins University, school of medicine, Baltimore, MD, ²Johns Hopkins University, School of Nursing, Baltimore, MD, ³Biostatistics, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD.

Oral Abstract Session

4606

Monday, March 06, 2006 2:00 pm to 3:15 pm

Eosinophils and Mast Cells

1045   Transduction of PTEN into Eosinophils Attenuates Survival and Chemotaxis

T. Adachi, S. Hanaka, S. Ueki, H. Nagase, K. Ohta; Internal Medicine, Teikyo University School of Medicine, Tokyo, JAPAN.

1046   FIP1L1-PDGFRα Induces Stem Cell Factor Dependent Eosinophil and Mast Cell Development from Murine Hematopoietic Stem Cell/Progenitors in Vitro

Y. Yamada ¹, J. A. Cancelas^2,3, A. W. Lee², D. A. Williams², M. E. Rothenberg¹; ¹Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Experimental Hematology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Hoxworth Blood Center, University of Cincinnati Medical Center, Cincinnati, OH.

1047   Expression and Inhibitory Function of Siglecs on Culture-Derived Human Mast Cells (MC)

H. Yokoi ¹, K. Matsumoto², P. R. Crocker³, H. Saito⁴, C. A. Bickel¹, W. Hubbard¹, S. A. Hudson¹, B. S. Bochner¹; ¹Division of Allergy and Clinical Immunology, Johns Hopkins Asthma and Allergy Center, Baltimore, MD, ²Division of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN, ³Division of Cell Biology and Immunology, The Wellcome Trust Biocentre, University of Dundee, Dundee, UNITED KINGDOM, ⁴Department of Allergy and Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN.

1048   Intestinal Peristaltic Reflex (IPR) is Regulated by Mast Cells and IL-9

K. R. Groschwitz ¹, E. Forbes², E. B. Brandt¹, K. I. Matthaei², S. P. Hogan¹; ¹Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Allergy and Inflammation Research Group, The John Curtin School of Medical Research, Canberra, AUSTRALIA.

Oral Abstract Session

4607

Monday, March 06, 2006 2:00 pm to 3:15 pm

Rhinoconjuntivitis

1049   Mechanism of Tissue Remodeling in a Murine Model of Chronic Allergic Conjunctivitis

C. K. Oh ¹, J. Davidson¹, S. Baik¹, Z. Yao², R. Martin²; ¹Pediatrics, Harbor-UCLA Medical Center, Torrance, CA, ²Tanox Inc., Houston, TX.

1050   Ocular Olopatadine Treatment of Seasonal Allergic Conjunctivitis Decreases the Ability of Tears to Promote In Vitro Eosinophil Adhesion to Tear-Stimulated Conjunctival Epithelial Cells

E. B. Cook ¹, J. L. Stahl¹, J. B. Sedgwick¹, A. M. Brooks¹, F. M. Graziano¹, N. P. Barney²; ¹Medicine, University of Wisconsin, Madison, WI, ²Ophthalmology & Visual Science, University of Wisconsin, Madison, WI.

1051   The Role of IL-13 in the Development of Allergic Rhinitis in Mice

S. Miyahara, N. Miyahara, S. Matsubara, T. Koya, K. Takeda, E. W. Gelfand; pediatrics, National Jewish Medical and Research Center, Denver, CO.

1052   Value of Measuring Nasal IgE in Subjects with Seasonal Rhinitis

N. FUIANO ^1,2, D. Procaccini³, C. Incorvaia⁴; ¹Pediatric allergy service, A.USL FG 1, San Severo, ITALY, ²Pediatrics, National Health, San Severo, ITALY, ³Nephrology Dpt., OO.RR., Foggia, ITALY, ⁴Reumatology/Allergology Unit, I.C.P., Milano, ITALY.

Poster Session

5201

Tuesday, March 07, 2006

9:45 am to 10:45 am

Managment of Asthma with Education and Alternative Therapy

1053   Update on the Effect of a Multidisciplinary Team (MDT) Clinic on Asthma Outcome for Medicaid-Eligible Inner City Children with Moderate to High-Risk Asthma

P. P. PATEL, G. DHILLON, J. MELLESMOEN, P. SEIGEL, P. MUNZENBERGER, R. RICH, E. SECORD; Allergy and Immunology, CARMAN AND ANN ADAMS DEPARTMENT OF PEDIATRICS, CHILDREN'S HOSPITAL OF MICHIGAN - WAYNE STATE UNIVERSITY, DETROIT, MI.

1054   Non-Classical Symptoms used by Inner-City Hispanics to Describe Asthma Attacks

R. A. Vicens; University of Puerto Rico School of Medicine, San Juan, PR.

1055   Asthma Severity Predicts Future Asthma Morbidity in Inner-City Preschool Children but Controller Medication Use is Not an Important Additional Predictor

H. P. Sharma ¹, E. C. Matsui¹, P. A. Eggleston¹, S. L. Swords¹, G. B. Diette²; ¹Department of Pediatrics, Johns Hopkins School of Medicine, Baltimore, MD, ²Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD.

1056   Factors Predictive of Future Clinically Significant Exacerbations in Severe Asthma

R. Slavin ¹, H. Fox², K. Surrey², C. Reisner³; ¹Saint Louis University School of Medicine, Saint Louis, MO, ²Novartis Horsham Research Centre, Horsham, UNITED KINGDOM, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ.

1057   Improving Influenza Vaccination Rates in a Pediatric Asthma Management Program by Utilization of an Electronic Medical Record

E. Martin; Health Point Family Care, Covington, KY.

1058   Which Patients are More Likely to Receive an Asthma Action Plan?

D. C. Chaffin, Jr., K. K. Slish, M. D. Cabana, N. M. Clark; Division of Allergy/Immunology, University of Michigan, Ann Arbor, MI.

1059   Asthma Education Camp : Immediate and Long term Impacts on Thai Asthmatic Children and Their Families

S. Numkiatwongsa ¹, T. Tongkaew¹, S. Tongkum², P. Chatchatee¹, J. Ngamphaiboon¹; ¹Pediatric, Chulalongkorn University School Medicine, Bangkok, THAILAND, ²Rehabilitation and physiotherapy, Chulalongkorn University School Medicine, Bangkok, THAILAND.

1060   A School Based Asthma Intervention Program For Asthma And Allergic Emergencies

M. D. Moncino ¹, C. Hammen², N. Rithmire³, K. A. Sheerin¹; ¹Breathe Georgia, Atlanta, GA, ²Mt Vernon Presbyterian School, Atlanta, GA, ³Forsyth County Schools, Forsyth, GA.

1061   Assessment of Asthma Exacerbations in a Real-World Setting over 4 Years

R. O'Connor ¹, D. Tashkin², S. Peters³, A. Long⁴, E. Bleecker³, B. Parasuraman⁵, R. Boggs⁵; ¹Sharp Rees-Stealy Medical Group, San Diego, CA, ²University of California at Los Angeles, Los Angeles, CA, ³Wake Forest University, Winston-Salem, NC, ⁴Massachusetts General Hospital, Boston, MA, ⁵AstraZeneca, Wilmington, DE.

1062   Children with Asthma Post Adenotonsillectomy: A Prospective Analysis

D. E. Karas, K. Farmer, W. Mackey; Yale University, New Haven, CT.

1063   Results of a Two Week Intensive Educational Intervention for Asthma in Children

G. Schauerte; CJD Asthmazentrum Berchtesgaden, Berchtesgaden, GERMANY.

1064   Therapy of Established Chronic Experimental Asthma with a Low Molecular Weight Ccr-3 Antagonist

M. Wegmann ¹, R. Goeggel², S. Sel¹, K. J. Erb², F. Kalkbrenner², H. Renz¹, H. Garn¹; ¹Department of Clinical Chemistry and Molecular Diagnostics, Hospital of the Philipps-University Marburg, Marburg, GERMANY, ²Department of Pulmonary Research, Boehringer Ingelheim Pharma GmbH, Biberach, GERMANY.

1065   Effect of Anti-Reflux Medical Treatment on Respiratory Symptoms of Asthma Patients Less than 24 Months Old

M. Oh, J. Becker; Allergy, St. Christopher's Hospital for Children, Philadelphia, PA.

1066   Potent and Persistent Effects of an Anti-Asthma Herbal Formula (ASHMI) on Severe Allergic Airway Responses in Chronic Asthma Model

S. M. Termanini; Pediatric Allergy and Immunology, Mount Sinai School of Medicine, New York, NY.

1067   Patients with Intermittent Asthma Account for a Substantial Portion of Asthma-Related Hospital Emergency Department Visits

R. T. Hsu ¹, W. W. Crawford², W. B. Klaustermeyer¹; ¹Allergy and Immunology, VA Greater Los Angeles Healthcare System, Los Angeles, CA, ²Allergy and Immunology, Kaiser Permanente, Harbor City, CA.

1068   The Use of Macrolide Antibiotics in the Management of Asthma

F. Abrahamian, J. Vintch; Internal Medicine, Harbor-UCLA Medical Center, Torrance, CA.

1069   Asthma Care Practices of Pediatricians in Incheon, Korea and Adherence to Asthma Guidelines

Y. Sun, D. In, J. Kim; Pediatrics, Gachon Medical School, Icheon, REPUBLIC OF KOREA.

Poster Session

5202

Tuesday, March 07, 2006

9:45 am to 10:45 am

Diagnosis and Managment of Allergy, Asthma and Immunology

1070   The Chinese Herbal Formula CUF2 Modulates Th1/Th2 Responses in a Rat Model of Allergic Asthma

Y. O. Wong ¹, R. Y. T. Sung¹, K. Li¹, Y. Zhao², A. M. Li¹, Y. X. Bao³, T. F. Fok¹, K. P. Fung²; ¹Dept of Paediatrics, The Chinese University of Hong Kong, Hong Kong, CHINA, ²Institute of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong, CHINA, ³Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, CHINA.

1071   Characterization of The Protective and Therapeutic Efficiency of a DNA Vaccine Encoding The Cockroach Allergen Bla g 1

B. Zhou, M. Ensell, J. Glickstein, C. Cai, M. Kermany, Q. Cai, T. J. Yoo; Department of Medicine, University of Tennessee, Memphis, TN.

1072   Immunoregulatory Effects of Saccharomyces (S.) cerevisiae Mannan via Th2/Th3 Polarization in Mice

J. M. Lehman, M. R. Streck, A. S. Tyagi, D. B. Lew; Pediatrics, University of Tennessee Health Science Center, Memphis, TN.

1073   Immunologic Changes after Long-Term Immunotherapy with Hop Japanese Pollen Extracts

S. Lee ¹, S. Kim², Y. Ye², S. Kim³, S. Kim², D. Nahm², H. Park²; ¹Internal Medicine, Dong-A University, Busan, REPUBLIC OF KOREA, ²Allergy and Rheumatology, Ajou University, Suwon, REPUBLIC OF KOREA, ³Internal Medicine, Seoul National University, Seoul, REPUBLIC OF KOREA.

1074   Induction of Rabbit Specific IgG against Der p 1 and Der p 2 after Immunization with an Allergoid of Dermatophagoides Pteronyssinus

E. Fernández-Caldas, M. Gallego, J. Carnés, M. Casanovas, V. Iraola; Laboratorios LETI S.L., Tres Cantos, SPAIN.

1075   Reproducibility of Missing doses as a Predictor of Poor Medication Adherence in Patients Receiving Specific Immunotherapy

P. A. Mahesh ¹, V. pudupakkam², A. D. Holla³, V. Rajesh³; ¹JSS Medical College, Mysore, INDIA, ²University of Colorado Health Sciences, Colorado, CO, ³Allergy Asthma and Chest Center, Mysore, INDIA.

1076   Protollin Adjuvanted Birch Pollen Extract Induces Long-Term Prevention of Airway Inflammation in a Mouse Model of Allergic Asthma

C. R. Rioux ¹, N. Karp², H. Koohsari¹, A. Migneault¹, D. S. Burt¹, J. G. Martin², Q. A. Hamid²; ¹ID Biomedical, Laval, PQ, CANADA, ²McGill University, Montreal, PQ, CANADA.

1077   Effects of Tacrolimus on Neutrophil Superoxide Production in Asthmatics Compared to Controls

S. M. Bonilla, N. Bobba, E. Park, B. Goldberg; Allergy and Immunology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, CA.

1078   The Effect of BCG Treatment on the Allergic Responses in a Murine Model of Chronic Asthma

S. S. Kwon, C. H. Kim, J. H. Ahn, S. Y. Lee, S. J. Kim, Y. K. Kim, K. H. Kim, H. S. Moon, J. S. Song, S. H. Park; Dept. of Internal Medicine, Catholic University of Korea, Medical College, Seoul, REPUBLIC OF KOREA.

1079   IgE Immunotherapy Efficiently Induces Neutralizing Anti-Human IgE Antibodies in Primates

Å. Jansson, A. Fuentes, E. Landström, S. Persson, B. Xu; Resistentia Pharmaceuticals AB, Uppsala, SWEDEN.

1080   Omalizumab Reduced Need for Steroid Bursts in Asthmatics Concomitantly Using Leukotriene Receptor Antagonists (LTRAs)

R. Zeldin ¹, M. Massanari¹, R. Maykut¹, F. Kianifard¹, Y. Deniz², C. Reisner¹, G. Geba¹; ¹Novartis, East Hanover, NJ, ²Genentech, So San Francisco, CA.

1081   Comparison of Multi-Test II and Skintestor Omni Allergy Skin Test Devices

M. S. Dykewicz, J. K. Lemmon, D. L. Keaney; Allergy/Immunology, Internal Medicine, St. Louis University Medical School, Saint Louis, MO.

1082   Measuring Airway Hyperresponsiveness: Does it Add to Routine Measures of Clinical Efficacy in Guiding Asthma Therapy?

J. Stauffer, S. Yancey, L. Baitinger, B. Prillaman, P. Dorinsky; GlaxoSmithKline, Research Triangle Park, NC.

1083   Seroatopy in Childhood-Onset and Adult-Onset Asthma

C. M. Abraham ¹, E. L. Peterson², G. Wegienka², M. Maliarik², E. M. Zorratti², C. C. Johnson², D. R. Ownby¹; ¹Medical College of Georgia, Augusta, GA, ²Henry Ford Health System, Detroit, MI.

1084   Impulse Oscillometry System (IOS) as a Method of Early Detection of Lower Airway Obstruction in Patients with Allergic Rhinitis (AR)

G. K. Deogun ¹, M. Cooper², S. Hauptman², G. D. Sharma²; ¹Allergy and Immunology, Rush University Medical Center and Stroger Hospital of Cook County, Chicago, IL, ²Section of Pediatric Pulmonology, Rush University Medical Center, Chicago, IL.

1085   Association of MS4A2 Gene Polymorphisms with a Susceptibility to Aspirin-Intolerant Asthma

S. H. Kim, J. S. Bae, Y. M. Ye, C. H. Suh, D. H. Nahm, H. S. Park; Department of Allergy and Rheumatology, Ajou University School of Medicine, Suwon, REPUBLIC OF KOREA.

1086   Effects of Inhaled Corticosteroids on Exhaled Breath Condensate (EBC) pH and Cytokines Levels in Children with Asthma and Atopic Dermatitis (AD)

R. Tesse, F. Fiore, O. Sillecchia, M. Mastronardi, R. Procacci, D. Locantore, L. Armenio, L. M. Brunetti; Department of Pediatrics-U.O. Maggiore, University of Bari, Bari, ITALY.

1087   Myasthenia Gravis Presenting as Restrictive Lung Disease

M. M. Montalbano ¹, M. Bowman¹, D. Stickler²; ¹Pediatric Pulmonary, Asthma, Allergy & Immunology, Medical University of South Carolina, Charleston, SC, ²Pediatric Neurology, Medical University of South Carolina, Charleston, SC.

1088   Allergen-Induced Late Cutaneous Responses Are Associated with Elevated CD3⁺CCR4⁺ Cells and no Change in CD3⁺CCR3⁺ or CD3⁺CCR8⁺ Cells

S. C. Martins ¹, K. T. Nouri-Aria¹, G. K. Banfield¹, M. R. Jacobson¹, H. Watanabe¹, S. Radulovic¹, D. S. Robinson¹, C. M. Lloyd², S. R. Durham¹; ¹Upper Respiratory Medicine, National Heart and Lung Institute at Imperial College London, London, UNITED KINGDOM, ²Leukocyte Biology, Imperial College London, London, UNITED KINGDOM.

Poster Session

5203

Tuesday, March 07, 2006

9:45 am to 10:45 am

HIV and Primary Immunodeficiency - 2

1089   Penicillosis in Patients with X-linked Hyperimmunoglobulin M Syndrome (XHIGM), Case Reports from Thailand

W. Kamchaisatian ¹, P. Kosalaraksa², S. Benjaponpitak¹, S. Hongeng¹, C. Direkwattanachai¹, P. Lumbiganon², S. Wiangnon²; ¹Division of Allergy/Immunology, Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, THAILAND, ²Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, THAILAND.

1090   Coronary Artery Aneurysms in a Patient with Hyperimmunoglobulinemia E Syndrome

T. Young ¹, D. Jerome², S. Gupta¹; ¹U.C. Irvine, Irvine, CA, ²Long Beach VA Hospital, Long Beach, CA.

1091   Treatment of Pyoderma Gangrenosum (PG) with Infliximab in Leukocyte Adhesion Deficiency (LAD) Type 1

K. P. Shanks ¹, E. J. Popek², S. L. Abramson¹; ¹Department of Pediatrics, Section of Allergy and Immunology, Baylor College of Medicine, Houston, TX, ²Department of Pathology, Baylor College of Medicine, Houston, TX.

1092   A Case of Hyper IgM Syndrome with an Intronic Point Mutation at Intervening Sequence 2, Position 16 in Activation-Induced Cytidine Deaminase (AID) Gene

R. J. Marchlewski, D. W. Rosenthal, V. R. Bonagura; Allergy & Immunology, North Shore Long Island Jewish Health System, New Hyde Park, NY.

1093   Hypogammaglobulinemia Associated with Rituximab Therapy after Bone Marrow Transplantation

N. D. Hare, A. M. Dowden, Z. K. Ballas; University of Iowa, Iowa City, IA.

1094   The Use of Low Dose Intramuscular Immunoglobulin for Prophylaxis against Recurrent Respiratory Tract Infections and Varicella Infections in Children with Mitochondrial Disorders

S. S. Wallace, R. W. Hostoffer, Jr.; Pediatrics, Case Western Reserve University, Cleveland, OH.

1095   Neutropenia, With a Cyclical Pattern, In Antibody Deficiency

A. Azar, Z. Ballas; Allergy/Immunology, University of Iowa Health Care and the Iowa City VA Medical Center, Iowa City, IA.

1096   Oral Immunoglobulin Therapy in a Child with Severe Clostridium Difficile Diarrhea

E. J. Saturno ^1,2, H. Costa³, R. Sorensen²; ¹Pediatrics, Pediatric Specialty Center, West Jefferson Medical Center, Marrero, LA, ²Pediatric, division of A/I, LSU Health Sciences Center, New Orleans, LA, ³Clinica de Alergia, Asma e Inmunologia, Panama, PANAMA.

1097   Immunoglobulin Deficiency in Stickler Syndrome

Z. Mikhak, P. Kelly, T. S. Cohen, J. E. Cox; Healthy Link Asthma Education Program, Children's Hospital Boston, Boston, MA.

1098   Case Series of Juvenile Arthritis in Two Females With Autosomal Recessive Agammaglobulinemia

R. F. Lavi, N. Tangsinmankong, N. K. Day, J. W. Sleasman; Division of Allergy/Immunology/Rheumatology, University of South Florida/All Children's Hospital, Saint Petersburg, FL.

1099   A Clinical Study of Primary Immunodeficiency Disease in a Single Center in Seoul from 1996 to 2004

S. Park; Samsung Seoul hospital, Seoul, REPUBLIC OF KOREA.

1100   Pro- and Anti-Sleep Cytokines Regulate Attention and Sleep Disorders in Older Children and Adolescents with Advanced HIV Disease

S. B. Foster ¹, M. E. Paul¹, D. G. Glaze¹, J. M. Reuben², L. L. Harris¹, E. N. Cohen², B. Lee², C. A. Kozinetz¹, S. G. Cron¹, H. L. Schwarzwald¹, M. W. Kline¹, C. D. Jackson¹, A. J. Loeb¹, P. R. Frerking, Jr.¹, P. Y. Brouwers¹, W. T. Shearer¹; ¹Pediatrics, Baylor College of Medicine, Houston, TX, ²Hematopathology, University of Texas, MD Anderson Cancer Center, Houston, TX.

1101   Distinct Anti-HIV-1 Specificities Among Different Immunoglobulin Isotypes Before and After HAART

A. Kuver, M. H. Bluth, J. Moallem, H. G. Durkin, M. Nowakowski; Center for Allergy and Asthma Research, SUNY Downstate Medical Center, Brooklyn, NY.

1102   Il-21 Upregulates CD8 T Cell Immune Function in HIV-Infected Individuals

S. Krishnan, S. Pahwa, N. Strbo, M. Kolber; University of Miami-Miller School of Medicine, Miami, FL.

1103   Virologic Outcome of Gastrostomy Tube Insertion in Treatment-Experienced Pediatric HIV-Infected Patients

S. M. Fung ¹, J. Shliozberg²; ¹Division of Allergy and Immunology, Albert Einstein College of Medicine, Bronx, NY, ²Department of Pediatrics, Children's Hospital at Montefiore Medical Center, Bronx, NY.

1104   Investigation of Pediatric and Adolescent HIV Practitioner Prescribing Practices as Compared to National Guidelines

C. Cotronei-Cascardo ¹, C. Rongkavilit², E. Secord¹; ¹Allergy-Immunology, Wayne State University, Children's Hospital of Michigan, Detroit, MI, ²Infectious Disease, Wayne State University, Children's Hospital of Michigan, Detroit, MI.

1105   Different Patterns of Delayed-Type Hypersensitivity Skin Tests Reactivity in HIV-1-Infected and Non-Infected Children and Adolescentes Immunized with BCG in Central-West Brazil

N. M. X. Costa ¹, M. Albuquerque², J. B. A. Lins¹, A. M. R. Visconde¹, M. M. A. Stefani¹; ¹Immunology, Universidade Federal de Goias, Goiania - Goias, BRAZIL, ²Pediatrics, Hospital Anuar Auad, Goiania - Goias, BRAZIL.

1106   Suppressed Exhaled Nitric Oxide in HIV-1 Infected Children

O. Asimolowo, H. Muzumdar, N. Desai, M. Rao, H. G. Durkin, M. Nowakowski; Center for Allergy and Asthma Research, SUNY Downstate Medical Center, Brooklyn, NY.

1107   IgE and Atopy in Perinatally HIV-Infected Children

C. S. Bowser ¹, J. Kaye¹, C. Charlot², R. Joks², J. Moallem¹; ¹Pediatrics, Division of Allergy and Immunology, Center for Allergy and Asthma Research, SUNY Downstate Medical Center, Brooklyn, NY, ²Medicine, Division of Allergy and Immunology, Center for Allergy and Asthma Research, SUNY Downstate Medical Center, Brooklyn, NY.

1108   Intracellular IL-17 Expression in Peripheral Blood CD4+ and CD4- T Cells of HIV-Infected Individuals

W. Maek-A-Nantawat ¹, S. Buranapraditkun², K. Ruxrungthum²; ¹Mahidol University, Bangkok, THAILAND, ²Medicine, Chulalongkorn University, Bangkok, THAILAND.

Poster Session

5204

Tuesday, March 07, 2006

9:45 am to 10:45 am

Primary Immunodeficiency 3

1109   Severe Combined Immunodeficiency in Twins Presenting with Different T, B, and NK Cell Phenotypes

H. Tcheurekdjian ¹, M. Cowan², M. Muskat², D. Wara²; ¹Medicine and Pediatrics, University of California, San Francisco, San Francisco, CA, ²Pediatrics, University of California, San Francisco, San Francisco, CA.

1110   Clinical Features of Pediatric Immunology Patients Referred to a Tertiary Care Clinic

I. Warrier, E. Secord; Allergy and Immunology, Children's Hospital of Michigan/WSU, Detroit, MI.

1111   Suspected Atypical Common Gamma Chain Severe Combined Immunodeficiency

A. Chandra ¹, D. Webster², K. C. Gilmour³, D. S. Kumararatne¹, A. Thrasher³; ¹Clinical Immunology, Addenbrooke's Hospital, Cambridge, UNITED KINGDOM, ²Clinical Immunology, Royal Free Hospital, London, UNITED KINGDOM, ³Clinical Immunology, Great Ormand St Hospital, London, UNITED KINGDOM.

1112   Rapid In Vitro T-Cell Functional Assays May Fail to Detect Immunodeficiencies

R. K. Merchant, J. R. Perez, N. Y. Olson; Department of Pediatrics Division of Allergy and Immunology, University of Kansas Medical Center, Kansas City, KS.

1113   Characterization of Immune Function in a Patient with Ectopic Thymus

V. S. Kancherla ¹, S. B. Foster¹, C. Holsinger², M. Luna², J. Jones¹, C. Hanson¹; ¹Texas Childrens Hospital, Houston, TX, ²University of Texas at Houston Medical School, Houston, TX.

1114   Mycobacterium Avium Complex (MAC) Infection In 2 Siblings with Autosomal Recessive Interferon Gamma (INFγ) Receptor Deficiency (I87T)

C. Cotronei-Cascardo ¹, E. Secord¹, S. Ebbinghaus¹, S. Patel², S. Holland³; ¹Allergy-Immunology, Wayne State University, Children's Hospital of Michigan, Detroit, MI, ²Laboratory of Clinical Infectious Diseases, NIAID/NIH, Bethesda, MD, ³Laboratory of Clinical Infectoius Diseases, NIAID/NIH, Bethesda, MD.

1115   Prostacyclin-Induced Antibody Deficiency in the Treatment of Pulmonary Hypertension

A. M. Dowden ¹, Z. K. Ballas^1,2; ¹Department of Internal Medicine, University IA Hospitals and Clinics, Iowa City, IA, ²Iowa City VA Medical Center, Iowa City, IA.

1116   A Case of Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) Without Serological Evidence of Autoimmunity

P. Ponda ¹, D. W. Rosenthal¹, B. Kaplan¹, P. LoGalbo¹, S. J. Schuval¹, T. R. Torgerson², H. D. Ochs², V. R. Bonagura¹; ¹Department of Allergy and Immunology, North Shore Long Island Jewish Medical Center - Schneider Children's Hospital, Great Neck, NY, ²Pediatric Immunology, University of Washington and Children's Hospital Regional Medical Center, Seattle, WA.

1117   PET Imaging and Needle Biopsy in Granulomatous Variant-Common Variable Immunodeficiency (GD-CVID) with Peripheral Adenopathy

J. W. Blume, M. F. Sands; Allergy, Immunology, and Rheumatology, State University of New York at Buffalo, Buffalo, NY.

1118   Absence of Pre B Lymphocytes in a 16 Year Old Girl with Agammaglobulinemia and Cytopenias

C. S. Koenig ¹, M. Conley², K. A. DeMuth³, A. Irani¹; ¹Allergy-Immunology, Virginia Commonwealth University, Richmond, VA, ²Immunology, University of Tennessee College of Medicine, Memphis, TN, ³Allergy-Immunology, Washington University, St. Louis, MO.

1119   Gastrointestinal (GI) Involvement in Iranian Patients with Chronic Granulomatous Disease (CGD)

N. Shahnavaz, A. Aghamohammadi, A. Babaei Jandaghi, K. Abolmaali, N. Rezaei, M. Ezzati, A. Aghaei Lasboo, M. Movahedi, M. Moin; Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran, IRAN (ISLAMIC REPUBLIC OF).

1120   T Cell Repertoire in 22q11.2 Deletion Syndrome

J. Yu ¹, G. Uzel²; ¹Pediatrics, Division of Allergy and Immunology, Mount Sinai School of Medicine, New York, NY, ²NIAID, National Institutes of Health, Bethesda, MD.

1121   IPEX with Normal FOXP3 Gene and Diminished Expression

M. Solomon ¹, H. Ochs², R. Hostoffer, Jr.³; ¹Kirksville College of Osteopathic Medicine, Kirksville, MO, ²University of Washington, Seattle, WA, ³Pediatrics, Case Western Reserve University, Cleveland, OH.

1122   Mutation of NEMO Associated with Neutrophil Chemotaxis Abnormality

D. Alle ¹, J. Venglarcik², D. Williams³, J. Casanova⁴, R. Hostoffer, Jr.⁵; ¹Internal Medicine, Case Western Reserve University, Cleveland, OH, ²Pediatrics, Northeastern Ohio Universities College of Medicine, Rootstown, OH, ³Hematology, University of Cincinnati, Cincinnati, OH, ⁴Immunology, Necker Hospital, Paris, FRANCE, ⁵Pediatrics, Case Western Reserve University, Cleveland, OH.

1123   Autosomal Dominant Common Variable Immunodeficiency in a Large Pedigree

A. Marks ¹, B. Grimbacher², R. Hostoffer, Jr.¹; ¹Pediatrics, Case Western Reserve University, Cleveland, OH, ²Internal Medicine, University Hospital Freiburg, Frieburg, GERMANY.

1124   Impaired Immunity in May Hegglin Anomaly due to MYH9 Mutation

M. L. Heltzer, J. S. Orange; Allergy and Immunology, Children's Hospital of Philadelphia, Philadelphia, PA.

1125   Disseminated Mycobacterium tuberculosis Infection Due to IFN-γ Deficiency. Response to Replacement Therapy

S. L. Seneviratne ¹, J. Macfarlane², R. Doffinger³, L. Ceron-Gutierrez³, M. Amel Kashipaz¹, A. Robbins¹, T. Patel¹, P. T. Powell¹, D. S. Kumararatne³, R. J. Powell¹; ¹Clinical Immunology Unit, Queens Medical Centre, Nottingham, UNITED KINGDOM, ²Respiratory Medicine Department, Nottingham City Hospital, Nottingham, UNITED KINGDOM, ³Department of Clinical Immunology, Addenbrookes Hospital, Cambridge, UNITED KINGDOM.

1126   Novel Mutation of BTK Gene in an XLA Patient with Late Manifestation of Chronic Arthritis, Encephalopathy and Pseudomonas Sepsis

W. Manuyakorn ¹, W. Kamchaisatian¹, S. Benjaponpitak¹, D. Wattanasirichaigoon², C. Direkwattanachai¹; ¹Pediatrics, Division of Allergy/Immunology, Ramathibodi Hospital,Mahidol University, Bangkok, THAILAND, ²Pediatrics, Division of genetic, Ramathibodi Hospital,Mahidol University, Bangkok, THAILAND.

1127   Cartilage-Hair Hypoplasia Syndrome: A Pediatric Case Report of Nonalcoholic Steatohepatitis and Liver Failure

I. S. Randhawa, G. Yanni; Allergy & Immunology, Loma Linda University Medical Center- UCLA West Los Angeles VA, Los Angeles, CA.

1128   Ectodermal Dysplasia (ED) and Recurrent Pneumonia in a Ten Year Old Girl

M. Bathija ¹, D. McDonald², M. Adams¹, E. V. Bawle³, R. S. Geha², E. A. Secord¹; ¹Division of Allergy, Immunology & Rheumatology, Wayne State University/Children's Hospital of Michigan, Detroit, MI, ²Division of Immunology, Children's Hospital Boston, Boston, MA, ³Division of Genetics and Metabolic Disorders, Wayne State University/Children's Hospital of Michigan, Detroit, MI.

1129   Atopic Patient with Cyclic Neutropenia Associated

R. Cordoba Cordoba, M. E. Gonzalez Serrano, A. T. Staines Boone, G. López; Alergia e Inmunologia Pediatrica, Instituto Nacional de Pediatria, Mexico City, MEXICO.

Poster Session

5205

Tuesday, March 07, 2006

9:45 am to 10:45 am

Asthma: Epidemiology, Risk Factors, Intervention and Public Health

1130   The First Nation-Wide Survey on the Prevalence of Asthma for School Children by Using ISAAC Questionnaire in Japan

M. Akashi ^1,2, Y. Ohya^1,2, M. Futamura^1,2, N. Kojima^1,2, M. Narita^1,2, K. Akiyama², K. Takahashi², T. Nakagawa², F. Kobayashi², A. Eboshida², H. Nakamura², H. Odajima², Y. Adachi², A. Akasawa^1,2; ¹National Center for Child Health and Development, Tokyo, JAPAN, ²Japanese Asthma Survey Group, Tokyo, JAPAN.

1131   Comparison of the Prevalence of Wheeze, Persistent Rash and Doctor-Diagnosed Eczema in the Three South East Asian Cities of Jarkarta, Bandung and Singapore

K. Baratawidjaja ¹, B. Setabudiawan², Z. Munasir³, N. Kurniati³, T. N. Tan⁴, D. L. Lim⁴, B. W. Lee⁴, H. Van Bever⁴; ¹Medicine, University of Indonesia, Jarkarta, INDONESIA, ²Division of Allergy Immunology/Child Health Dept., Hasan Sadikin General Hospital, Bandung, INDONESIA, ³Pediatric, Cipto Mangunkusumo General Hospital, Jarkarta, INDONESIA, ⁴Paediatrics, National University of Singapore, Singapore, SINGAPORE.

1132   Prevalence of Asthma and Rhinitis Among Adolescents Living in Urban or Rural Areas of Different Cities of Brazil

D. Sole ¹, V. E. Cassol², A. R. Silva³, L. C. Bandim⁴, T. Rizatto², S. P. Teche², E. C. S. Sarinho³; ¹Pediatric Allergy, Federal University of São Paulo-Escola Paulista de Medicina, São Paulo, BRAZIL, ²Pediatric Pulmonology, Federal University of Santa Maria, Santa Maria, BRAZIL, ³Pediatrics, Federal University of Pernambuco, Recife, BRAZIL, ⁴Pediatrics, Federal University of Pernambuco, São Paulo, BRAZIL.

1133   Sensitization to Aeroallergens in Brazilian Adolescents Living at Large Urban Centers

A. C. Pastorino ¹, F. C. Kuschnir², L. C. P. Arruda³, R. R. D. Casagrande¹, R. G. L. Souza¹, G. A. C. Dias⁴, H. H. N. Silveira⁴, A. J. L. A. Cunha⁵, C. M. A. Jacob¹, D. Solé⁶; ¹Pediatric Department, Instituto da Criança, University of São Paulo, São Paulo, BRAZIL, ²Federal University of Rio de Janeiro, School of Medicine , Rio de Janeiro, Rio de Janeiro, BRAZIL, ³Department of Internal Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, Ribeirão Preto, BRAZIL, ⁴Secretariat of Civil Defense, School Health Program, Rio de Janeiro, BRAZIL, ⁵Pediatric Department, Federal University of Rio de Janeiro, Rio de Janeiro, BRAZIL, ⁶Pediatric Department, Escola Paulista de Medicina, Federal University of São Paulo, São Paulo, BRAZIL.

1134   Lifestyle, Sports Activities and Allergic Diseases

M. Bresciani ¹, C. Parisi¹, V. Porcaro², M. A. Schirru³, A. Torre⁴, M. Bonini¹, A. Biffi⁵, F. Fernando⁵, G. Rasi⁴, C. D'Ambrosio¹, S. Bonini¹; ¹IRCCS San Raffaele, Rome, ITALY, ²Istituto Malattie dell'Apparato Respiratorio, Università di Modena e Reggio Emilia, Modena, ITALY, ³USL Roma H, Rome, ITALY, ⁴INMM-CNR, Rome, ITALY, ⁵Istituto di Scienze dello Sport, Rome, ITALY.

1135   Influenza Vaccine Compliance among Pediatric Asthmatic Patients: What is the Better Method of Notification?

A. L. Parker ¹, M. L. Moore²; ¹Allergy/Immunology (Wilford Hall Medical Center), San Antonio Uniformed Services Health Education Consortiuim, Lackland AFB, TX, ²Department of Pediatrics, Shaw Air Force Base, 20th Medical Group, Shaw AFB, SC.

1136   The Relationship Between Allergen Sensitization and Bronchial Hyperresponsiveness in Children Aged 6-8 Years

J. Yu ¹, Y. Yoo², H. Kang³, D. Kim⁴, S. Choi⁴, Y. Koh⁴; ¹Pediatrics, Dongguk University International Hospital, Goyang, REPUBLIC OF KOREA, ²Pediatrics, Korea University Anam Hospital, Seoul, REPUBLIC OF KOREA, ³Pediatrics, Korea University Guro Hospital, Seoul, REPUBLIC OF KOREA, ⁴Pediatrics, Seoul National University Hospital, Seoul, REPUBLIC OF KOREA.

1137   Does Breast Feeding Protect Against Atopic Diseases?

M. Herrag; Paediatric Respiratory Diseases, Ibn Sina University Hospital, Rabat, MOROCCO.

1138   Topical Diclofenac Induced Asthma And Contact Dermatitis

H. Langer; Allergy And Immunology, Hospital For Sick Children, Toronto, ON, CANADA.

1139   Prevalence of Asthma and Rhinitis Symptoms Among 13 to 14-Year-Old Schoolchildren from Criciúma-SC, Brazil

J. BETTIOL ¹, C. C. RAASCH², M. B. SANTOS², J. C. SALVADOR², M. O. PRESADO², J. A. SCHMIDT²; ¹Medicine Department and Health Science Post-graduation Course, Universida de do Extremo Sul Catarinense - UNESC, Criciúma - Santa Catarina, BRAZIL, ²Medecine Department, Universidade do Extremo Sul Catarinense - UNESC, Criciúma - Santa Catarina, BRAZIL.

1140   Prevalence of Asthma Like Symptoms and Other Allergic Diseases in Scholars from Pamplona, Colombia

M. Sarrazola-Sanjuan, L. Gomez-Cabeza, E. Herrera; Universidad de Pamplona, Pamplona, COLOMBIA.

1141   Association between IgA and IgG1 Serum Level and Atopy in Children

P. Majak, J. Jerzynska, I. Stelmach; Dep. Allergy and Pediatrics, M Curie Hospital, Zgierz, POLAND.

1142   Asthma Prevalence in Public Housing Communities

J. Poyser, T. Richards, D. Collins, T. Green, R. Morgan, E. Horowitz, A. Togias; Johns Hopkins University, Baltimore, MD.

1143   Association of Mycoplasma Pneumoniae with Initial Wheezer for 3 Years Follow-Up

H. Yoon ¹, W. Kim²; ¹Hallym University, Seoul, REPUBLIC OF KOREA, ²Pediatrics, Inje University, Seoul, REPUBLIC OF KOREA.

1144   Anthropometric Measures and Lung Function Test in Asthmatic Pacients, Asthmatic Obese, Obese without Asthma and Healthy Pacients

J. E. Guillen Escalon, J. J. L. Sienra, G. Toussaint, M. A. Rosas, B. E. Del Rio; Pediatric Allergy and Immunology, Hospital Infantil de Mexico, Mexico DF, MEXICO.

Poster Session

5206

Tuesday, March 07, 2006

9:45 am to 10:45 am

Interesting Cross-sectional Studies and Case Reports

1145   Wheezing in a High Risk Cohort Predicts an Increased Prevalence of Positive Skin Test Results Relative to a General Population Sample

K. T. Sullivan Dillie ¹, E. L. Anderson¹, D. F. DaSilva¹, M. Evans², R. Gangnon², T. E. Pappas¹, L. E. Pleiss¹, K. A. Roberg¹, C. J. Tisler¹, J. E. Gern¹, R. F. Lemanske, Jr.¹; ¹Department of Pediatrics, University of Wisconsin - Madison, Madison, WI, ²Department of Biostatistics, University of Wisconsin - Madison, Madison, WI.

1146   Rhinitis and Asthma Caused by Sport Fishing

M. F. Madero ¹, M. Fernandez-Nieto¹, S. Quirce¹, C. Seoane², B. Sastre², V. del Pozo², C. Lahoz², J. Sastre¹; ¹Servicio de Alergia, Fundacion Jimenez Diaz, Madrid, SPAIN, ²Servicio de Inmunologia, Fundacion Jimenez Diaz, Madrid, SPAIN.

1147   Association between Obstructive Sleep Apnea Syndrome and Atopy in Children

P. L. Ramirez ¹, U. Emre¹, A. Schneider²; ¹Pediatrics, Long Island College Hospital, Brooklyn, NY, ²Allergy and Immunology, Long Island College Hospital, Brooklyn, NY.

1148   Importance of Polysensitization in Allergic Rhinitis and Asthma

G. Moscato ¹, L. Perfetti¹, R. Cantone², L. La Rosa², C. Cosentino³, L. Berardi⁴, P. Puccinelli⁵, C. Incorvaia⁶, F. Frati⁵; ¹Allergy Center, Istituto Maugeri, Pavia, ITALY, ²Allergy Service, General Hospital, Borgomanero, ITALY, ³Allergy Service, General Hospital, Tortona, ITALY, ⁴Dermatology, Policlinico S. Matteo, Pavia, ITALY, ⁵Scientific Department, Stallergenes Italy, Milan, ITALY, ⁶Allergy/Rheumatology, ICP Hospital, Milan, ITALY.

1149   An Unusual Case of Red Tide Poisoning

M. Sanka; Allergy and Immunology, Uinversity of South Florida, Tampa, FL.

1150   Allergies: Our Reality

J. L. Rodríguez Barata; Centro Médico Familiar, San Marcos, Tarrazú. San José., COSTA RICA.

1151   House Dust Mites Survive Travel in the Baggage Compartment of Commercial Jet Airliners

J. D. Miller; Allergy & Asthma Associates, PC, Danbury, CT.

1152   Onset of Nasal Symptoms Induced by the Pollen of Cryptomeria fortunei in a Japanese Patient with Cedar Pollinosis: A Clinical Pilot Study

L. Cheng ¹, H. B. Shi², M. Yin¹, A. Miyoshi²; ¹International Research Centre for Nasal Allergy, Nanjing Medical University, The First Affiliated Hospital, Nanjing, CHINA, ²International Research Centre for Nasal Allergy, Nanjing Medical University, Miyoshi ENT Clinic, Sendai, JAPAN.

1153   The Efficacy of Medic-Air™ in Patients with Dust Mite Allergy

Z. M. Sthoeger ¹, D. Elbirt¹, S. Kivity²; ¹Kaplan Medical Center, Rehovot, ISRAEL, ²Sourasky Medical Center, for the Israeli Medic-Air™ study group, Tel-Aviv, ISRAEL.

1154   Identifying Domestic Aeroallergen Exposure in a Cystic Fibrosis Patient: A Case Study

J. K. Sercombe ¹, D. Liu-Brennan¹, B. J. Green², E. R. Tovey¹; ¹Woolcock Institute of Medical Research, Sydney NSW, AUSTRALIA, ²Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV.

Poster Session

5207

Tuesday, March 07, 2006

9:45 am to 10:45 am

The Role of Food from the GUT to the Skin

1155   Faecal Eosinophilic Protein X (f-EPX), Atopic Dermatitis, Sensitisation and Gastrointestinal Permeability in Infants Aged 3-6 Months

C. Peterson ¹, T. Hansson¹, E. Hadley², C. Chaloner³, A. Woodcock², A. Custovic², C. Gore²; ¹Gastrointestinal Research, Pharmacia Diagnostics, Uppsala, SWEDEN, ²North West Lung Research Centre, Manchester, UNITED KINGDOM, ³Department of Biochemistry, Booth Hall Children's Hospital, Manchester, UNITED KINGDOM.

1156   Gastrointestinal Permeability is Abnormal in Young Infants with Atopic Dermatitis but Not Associated with Disease Severity or Sensitisation

C. Gore ¹, E. Hadley¹, C. Chaloner², G. Kerry¹, K. Johnson¹, A. Woodcock¹, A. Custovic¹; ¹Wythenshawe Hospital, North West Lung Research Centre, Manchester, UNITED KINGDOM, ²Booth Hall Children's Hospital, Manchester, UNITED KINGDOM.

1157   Diagnosing Egg and Milk Hypersensitivity in Children with Atopic Dermatitis using Atopy Patch and Skin Prick Tests

M. Yazicioglu ¹, U. Ozdagli¹, D. Kircuval², A. Gorgulu², O. Pala¹; ¹Department of Pediatrics, Trakya University, Edirne, TURKEY, ²Department of Dermatology, Trakya University, Edirne, TURKEY.

1158   Distinguishing Features of Eosinophilic Esophagitis in Children

S. S. Aceves ¹, R. O. Newbury², R. Dohil³, J. Schwimmer³, J. F. Bastian¹; ¹Allergy, Immunology, Children's Hospital, San Diego, University of California, San Diego, San Diego, CA, ²Pathology, Children's Hospital, San Diego, San Diego, CA, ³Pediatric Gastroenterology, University of California, San Diego, Children's Hospital, San Diego, San Diego, CA.

1159   Increased Intestinal Permeability in Asymptomatic Children with Food Allergy

K. M. Jarvinen ¹, J. Meddings², S. Noone¹, H. A. Sampson¹, M. C. Arrieta², A. Nowak-Wegrzyn¹; ¹Allergy and Immunology, Mt. Sinai Medical Center, New York, NY, ²University of Alberta, Edmonton, AB, CANADA.

1160   The Expression Frequency of Th1/Th2-Positive Cells and the Antiallergic Effect of Oligosaccharide in a Food Allergy Mouse Model

S. Fujitani, K. Ueno, T. Kamiya, T. Kitabayashi, K. Itabashi; Department of Pediatrics, Showa University, TOKYO, JAPAN.

1161   Descriptive Study of Food and Aeroallergen Sensitizations in Eosinophilic Esophagitis

A. Letran Camacho ¹, T. Caballero Molina¹, A. Lucendo Villamarin², B. Cid Sánchez¹, M. Martín Esteban¹, C. López Serrano¹; ¹Allergy Department, Hospital Universitario La Paz, Madrid, SPAIN, ²Gastroenterology Department, Hospital Universitario La Paz, Madrid, SPAIN.

1162   Severe Reactions to Grape, As Part of a Lipid Transfer Protein-Associated Clinical Syndrome

E. Vassilopoulou ¹, J. Akkerdaas², I. Tassios¹, N. Rigby³, L. Zuidmeer², R. van Ree², C. Mills³, P. Saxoni-Papageorgiou¹, N. G. Papadopoulos¹; ¹Research Laboratories of 2nd Paediatric Clinic, University of Athens, Athens, GREECE, ²Academic Medical Centre, University of Amsterdam, Amsterdam, THE NETHERLANDS, ³Institute of Food Research, Norwich, UNITED KINGDOM.

1163   Allergic Reactions to Fresh Fruits: Beyond Oral Symptoms

J. Rodriguez, R. Mielgo, A. Gonzalez, J. F. Crespo; Servicio de Alergia, Hospital Universitario 12 de Octubre, Madrid, SPAIN.

1164   Prevalence of Skin Test Reactivity to Tomato Peel and Pulp Extracts in the Mediterranean Coast of Spain

A. Ferrer¹, C. Larramendi², J. Huertas³, J. García-Abujeta², C. Andreu¹, R. Tella⁴, M. Cerdà⁴, J. Lavin³, J. Pagán⁵, J. Bartra⁶, J. Carnés⁷, E. Fernández-Caldas ⁷; ¹Hospital Vega Baja, Alicante, SPAIN, ²Hospital Marina Baixa, Alicante, SPAIN, ³Hospital General Básico de la Defensa, Cartagena, SPAIN, ⁴Hospital Universitari de Girona, Gerona, SPAIN, ⁵Hospital Virgen de la Arrixaca, Murcia, SPAIN, ⁶Hospital Clínic de Barcelona, Barcelona, SPAIN, ⁷Laboratorios LETI S.L., Tres Cantos, SPAIN.

1165   Immunochemical Characterization of Tomato Peel and Pulp Extracts

J. Carnés ¹, M. López-Matas¹, A. Ferrer², C. Larramendi³, J. Huertas⁴, M. Casanovas¹, E. Fernández-Caldas¹; ¹Laboratorios LETI S.L., Tres Cantos, SPAIN, ²Hospital de la Vega Baja, Alicante, SPAIN, ³Hospital Marina Baixa, Alicante, SPAIN, ⁴Hospital General Básico de la Defensa, Cartagena, SPAIN.

1166   Gene Silencing is an Efficient Tool to Reduce the Allergenic Potential of Tomato Fruits

Y. Lorenz; Allergology, Paul-Ehrlich-Institut, Langen, GERMANY.

1167   Cabbage Lipid Transfer Protein Bra o 3 is a Major Allergen Responsible for Cross-Reactivity between Plant Foods and Pollens

J. Cumplido¹, A. Palacín², J. Figueroa¹, O. Ahrazem², R. Sánchez-Monge², T. Carrillo¹, G. Salcedo², C. Blanco ¹; ¹Hospital Universitario Dr. Negrín, Las Palmas de GC, SPAIN, ²E.T.S. Ingenieros Agrónomos, Madrid, SPAIN.

1168   IgE-Binding Capacity and Cross-Reactivity of Lipid-Transfer-Proteins (LTP) from Peach (Pru p 3) and Hazelnut (Cor a 8)

C. Hartz ¹, I. Lauer¹, J. Lidholm², K. Fötisch¹, M. San Miguel-Moncin³, A. Cistero-Bahima³, S. Vieths¹, S. Scheurer¹; ¹Paul-Ehrlich-Institut, Langen, GERMANY, ²Pharmacia Diagnostics, Uppsala, SWEDEN, ³Institut Universitari Dexeus, Barcelona, SPAIN.

1169   Quantification and Regional Distribution of Eosinophils in the Gastrointestinal Tract of Children

C. W. DeBrosse ¹, J. W. Case², M. Collins³, M. E. Rothenberg¹; ¹Division of Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Division of Allergy and Immunology, Cincinnati Children's Hospitla Medical Center, Cincinnati, OH, ³Pathology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.

1170   Treatment of Eosinophilic Esophagitis with Low to Moderate Dose Swallowed Inhaled Corticosteroids

K. M. Maples ¹, S. Pustilnik¹, W. Zhao¹, T. Williams², M. Graham², A. Irani¹; ¹Rheumatology, Allergy and Immunology, Virginia Commonwealth University, Richmond, VA, ²Pediatric Gastroenterology, Virginia Commonwealth University, Richmond, VA.

1171   Resolution of Eosinophilic Esophagitis Following Dietary Restriction of Corn

R. M. Casper ¹, M. B. Levy¹, M. C. Stephens²; ¹Allergy and Immunology, Medical College of Wisconsin, Milwaukee, WI, ²Gastroenterology, Medical College of Wisconsin, Milwaukee, WI.

1172   Esophageal Fibrosis in Children with Allergic Eosinophilic Esophagitis (AEE)

M. Chehade ¹, H. A. Sampson¹, M. S. Magid²; ¹Pediatrics, Mt. Sinai School Medicine, New York, NY, ²Pathology, Mt. Sinai School Medicine, New York, NY.

1173   Food Protein-Induced Enterocolitis Syndrome Caused by Fish

G. Davila, L. Zapatero, E. Alonso, P. Rojas, E. Martin, I. Martinez-Molero; Pediatric Allergy Section, Hospital Gregorio Marañon, Madrid, SPAIN.

1174   Pilot Study of Omalizumab (anti-IgE) in Eosinophilic Gastroenteritis

S. Foroughi ¹, P. J. Mannon², L. B. Bernardino¹, B. Foster¹, L. M. Scott¹, D. D. Metcalfe¹, C. Prussin¹; ¹Laboratory of Allergic Diseases, NIAID, National Institutes of Health, Bethesda, MD, ²Mucosal Immunity Section, Laboratory of Host Defense, NIAID, National Institutes of Health, Bethesda, MD.

1175   Digestibility and Availability of Nitrogen for Whey Protein Hydrolysate Products Assessed Using a Dynamic In Vitro Gastrointestinal Model

K. Venema ¹, M. H. Dohnalek²; ¹Physiological Sciences, TNO Quality of Life, Zeist, THE NETHERLANDS, ²Abbott Nutrition International, Abbott Laboratories, Abbott Park, IL.

Poster Session

5208

Tuesday, March 07, 2006

9:45 am to 10:45 am

Anaphylaxis and Insect Sting

1176   Anaphylaxis, A Review of Emergency Department Management and Discharge Planning

F. Rezaee, J. Mendelson; Pediatrics, Newark Beth Israel Medical Center, Newark, NJ.

1177   Doctor - How Do I Use my Epipen?

S. S. Mehr, M. Robinson, M. Tang; Immunology Department, Royal Children's Hospital, Melbourne, Victoria, Melbourne, Victoria, AUSTRALIA.

1178   Factors Affecting the Use of Automatic Epinephrine Injectors (AEI)

M. Varghese, P. Lieberman; Medicine, University of Tennessee College of Medicine, Memphis, TN.

1179   Differences in Cytokine Production Between Idiopathic Anaphylaxis (IA) Subjects and Controls

J. Reed ¹, M. Yedulapuram¹, P. Lieberman¹, E. Fitzpatrick²; ¹Medicine, University of Tennessee College of Medicine, Memphis, TN, ²Microbiology, University of Tennessee College of Medicine, Memphis, TN.

1180   Recognition, Evaluation, and Treatment of Anaphylaxis in the Child Care Setting: Six Months and One Year Later

B. M. Patel ^1,2, P. J. Bansal^1,3, M. C. Tobin¹; ¹Department of Immunology and Microbiology, Department of Pediatrics, Rush University Medical Center, Chicago, IL, ²Department of Medicine, McGaw Medical Center, Northwestern University Evanston Hospital, Evanston, IL, ³Asthma & Allergy Center, Bloomingdale, IL.

1181   Exercise Induced Anaphylaxis: A Series from Guipúzcoa, Spain

J. A. Navarro ¹, O. Villarreal², A. Aranzabal³, A. Joral¹, J. F. Garmendia¹, S. Lizarza¹, E. Lasa¹; ¹Allergy Section, Hospital Donostia, San Sebastian, SPAIN, ²Allergy Section, Hospital Mendaro, Mendaro, SPAIN, ³Allergy Section, Hospital Zumarraga, Zumarraga, SPAIN.

1182   Clinical Evidence of a Priming Mechanism for Insect Sting Anaphylaxis

D. B. K. Golden ¹, R. G. Hamilton¹, S. Saini¹, D. Kelly¹, K. Chichester¹, N. Breisch², T. Craig³, J. Schroeder¹; ¹Johns Hopkins University, Baltimore, MD, ²University of Maryland, College Park, MD, ³Penn State Hershey Medical Center, Hershey, PA.

1183   Prescribing of EpiPen to Patients Presenting to an Inner-City Hospital Emergency Room (ER) with Acute Allergic Reactions

S. Amara, T. Tavartkiladze, Y. Persaud, B. Silverman, P. Hemmers, N. Gupta, A. T. Schneider; Alergy and Immunology, Long Island College Hospital, Brooklyn, NY.

1184   Usefulness of Serum Tryptase in the Diagnosis of Anaphylaxis by Food Allergy in Childhood

M. Narita ¹, I. Nomura¹, A. Aota¹, A. Saitoh¹, M. Akashi¹, M. Futamura¹, H. Watanabe¹, T. Suda¹, Y. Ohya¹, M. Ebisawa², A. Akasawa³; ¹Division of Allergy, National Center for Child Health and Development, Tokyo, JAPAN, ²Department of Allergy, National Sagamihara Hospital, Clinical Research Center, Sagamihara, JAPAN, ³Department of Interdisciplinary Medicine, National Center for Child Health and Development, Tokyo, JAPAN.

1185   Management of Acute Allergic Reactions and Anaphylaxis in the Emergency Department Between 1993-2003

S. Clark ¹, A. J. Pelletier¹, T. J. Gaeta², C. A. Camargo, Jr.¹; ¹Massachusetts General Hospital, Boston, MA, ²New York Methodist Hospital, Brooklyn, NY.

1186   Anaphylaxis in Patients with Mastocytosis - a Prospective Study on Prevalence, Severity and Trigger Factors in 121 Patients

K. Brockow, C. Jofer, J. Ring; Dpt. of Dermatology and Allergology Biederstein, Technical University Munich, Munich, GERMANY.

1187   Epidemiology of Hymenoptera Stings and Allergic Reactions in 10,000 Midschoolchildren- Results From a National Study

Y. Graif ¹, O. Romano-Zelekha², M. S. Green², T. shohat³; ¹allergy and immunology clinic,Pulmonary institute, Rabin Medical Center, Petach-Tiqva, ISRAEL, ²Israel center of disease control, Israel Ministry of Health, Tel-hashomer, ISRAEL, ³Tel-Aviv health district, Israel Ministry of Health, Tel-aviv, ISRAEL.

1188   Long-Term Effectiveness of Venom Immunotherapy (VIT)

T. Hafner, M. Kosnik; University Clinic of Respiratory and Allergic Diseases, Golnik, SLOVENIA.

1189   Identification of the Major Allergens of the Venom from the South American Social Wasp Agelaia Pallipes

C. E. S. Galvao ¹, L. K. Iwai², L. D. Santos³, M. A. Mendes³, M. S. Palma³, F. F. M. Castro¹, E. Cunha Neto², J. Kalil^1,2; ¹Clinical Immunology and Allergy, University of Sao Paulo Medical School, Sao Paulo, BRAZIL, ²Laboratory of Immunology - Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, BRAZIL, ³Biology Department, Institute of Biosciences, Center of Study of Social Insects, Sao Paulo State University - UNESP, Rio Claro, BRAZIL.

1190   Predictive Value of Sting Challenge

D. Kelly ¹, T. Grace¹, D. B. K. Golden¹, T. Craig², N. Breisch³, R. G. Hamilton¹; ¹Johns Hopkins University, Baltimore, MD, ²Penn State Hershey Medical Center, Hershey, PA, ³University of Maryland, College Park, MD.

1191   Comparison of North American and European Polistes Venom Allergens

C. D. Fitch¹, P. R. Morris¹, T. I. S. Moawad¹, M. Schmidt², D. R. Hoffman ¹; ¹Pathology and Laboratory Medicine, Brody School of Medicine, Greenville, NC, ²Biology, East Carolina University, Greenville, NC.

1192   A Cost-Effectiveness Analysis of Venom Desensitization in Children Treated for Cure and Risk-Reduction

K. F. Brown, M. S. Shaker, P. C. Jenkins, M. S. Verdi; Allergy and Clinical Immunology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.

1193   Expression of the Recombinant Honeybee Venom CUB Protease Allergen

M. Schmidt¹, N. M. Trulli², D. R. Hoffman ²; ¹Biology, East Carolina University, Greenville, NC, ²Pathology and Laboratory Medicine, Brody School of Medicine, Greenville, NC.

1194   Delayed and Recurrent Anaphylactic Reaction to Yellow Jacket Sting

G. Ghaffari ¹, T. Craig¹, D. Golden², S. Chegini¹; ¹Penn State Milton S Hershey Medical Center, Hershey, PA, ²Johns Hopkins University, Baltimore, MD.

1195   Production of a cDNA library to Harmonia Axyridis Multicolor Lady Beetle

C. Bermant, A. Pratt, M. Opsahl, H. Sanchez, R. K. Bush; Research, William S. Middleton VA Hospital, Madison, WI.

1196   Cimex Lectularius (Bedbug) Bites Presenting as Chronic Urticaria

M. R. Borts; Division of Allergy and Clinical Immunology, St. Louis University, St. Louis, MO.

Poster Session

5211

Tuesday, March 07, 2006

9:45 am to 10:45 am

IgE and IgE Receptors

1197   The Significance of Clonality and Affinity of Individual Allergen-Specific IgE Antibodies for the Activation of Human Basophils

L. H. Christensen, J. Holm, J. Skovsgaard, K. Lund; Research Department, ALK-Abelló A/S, Hørsholm, DENMARK.

1198   Expression Pattern and Function of Fc Epsilon RI-beta in Human Mast Cells

Y. Okayama ¹, A. Matsuda², K. Yuki¹, H. Katayama¹, H. Saito¹; ¹Research Unit for Allergy Transcriptome, RIKEN Yokohama Institute, Research Center for Allergy and Immunology, Yokohama, JAPAN, ²Laboratory for Genetics of Allergy Diseases, RIKEN Yokohama Institute, SNP Research Center, Yokohama, JAPAN.

1199   Essential Role for RasGRP1 in the IgE-dependent Allergic Response

Y. Liu; Department of Immunology, Duke University Medical Center, Durham, NC.

1200   Exposure to Repeated Early Childhood Infections in Relation to Atopy in Children Living in Orphanage

I. Stelmach, K. Smejda, J. Jerzynska; Department of Pediatrics and Allergy, Medical University of Lodz, M Curie Hospital, Zgierz, POLAND.

1201   Requirement of Fc Epsilon RI Gamma-subunit for IgE-mediated Up-regulation of Surface Fc Epsilon RI

H. Katayama ¹, S. Kagaya¹, K. Yuki¹, T. Arai², H. Saito^1,3, Y. Okayama¹; ¹Reserch Unit for Allergy Transcriptome, RIKEN Yokohama Institute, Yokohama, JAPAN, ²Laboratory of Seeds Finding Technology, Eisai Co., Ltd., Tsukuba, JAPAN, ³Department of Allergy & Immunology, National Research Institute for Child Health and Development, Tokyo, JAPAN.

1202   An IgE Antibody Reduce the Release of IL-5 from Mouse OVA treated CD34+ Hematopoietic Progenitor Cells In Vitro

M. Sjöstrand, A. Alm, A. Bossios, M. Rådinger, J. Lötvall; Respiratory Medicine and Allergology, Göteborg University, Gothenburg, SWEDEN.

1203   Increased Prevalence of Blomia Tropicalis Mite Allergens in Cord Blood of Patients with a Maternal History of Asthma

W. Chiang ¹, M. Iancovici Kidon¹, W. Liew¹, V. Rajadurai², F. Chew³; ¹Department of Paediatrics, KK Children's Hospital, Singapore, SINGAPORE, ²Department of Neonatology, KK Children's Hospital, Singapore, SINGAPORE, ³Institute of Biological Sciences, National University, Singapore, SINGAPORE.

1204   High Heritability of Total and Specific IgE levels in a Brazilian Population Endemic for Schistosomiasis

A. V. Grant ^1,2, M. I. Araujo³, K. Held², E. V. Ponte⁴, Á. A. Cruz⁴, T. H. Beaty¹, K. C. Barnes²; ¹Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ²Division of Allergy and Clinical Immunology, Department of Medicine, The Johns Hopkins University, Baltimore, MD, ³Servico de Imunologia, Hospital Universitario Professor Edgard Santos, Salvador, Bahia, BRAZIL, ⁴Brazil Center for Respiratory Diseases, Federal University of Bahia, Salvador, Bahia, BRAZIL.

1205   Is Human IgE+ Equivalent to Mouse Highly Cytokinergic (HC) IgE?

L. Xie, J. Langdon, R. Sora, S. M. MacDonald; Medicine/Division of Allergy and Clinical Immunology, JHUSM, Baltimore, MD.

1206   H3/H4 Histamine Receptor Antagonists Modulate IgE-Regulatory Cytokine Production

R. A. Khanferyan ¹, D. V. Lesik¹, L. M. DuBuske²; ¹Kuban State Medical Academy, Krasnodar, RUSSIAN FEDERATION, ²Immunology Research Institute of New England, Gardner, MA.

1207   IgE during Pregnancy is Not Associated with Number of Prior Live Births

G. Wegienka ¹, S. Havstad¹, D. R. Ownby², C. C. Johnson¹; ¹Department of Biostatistics and Research Epidemiology, Henry Ford Health System, Detroit, MI, ²Department of Allergy and Immunology, Medical College of Georgia, Augusta, GA.

1208   Agreement Between Results of an In Vitro Assay for Plasma Allergen-Specific IgE and Skin Testing in a High-Risk Birth Cohort

C. J. Tisler ¹, M. Evans², K. Roberg¹, E. Anderson¹, L. Pleiss¹, D. DaSilva¹, T. Pappas¹, R. Gangnon², J. Gern¹, R. Lemanske, Jr.¹; ¹Medical School, University of Wisconsin - Madison, Madison, WI, ²Biostatistics and Medical Informantics, University of Wisconsin - Madison, Madison, WI.

1209   Decrease in Skin Test Wheal and Flare Response after Omalizumab Therapy

A. Banerji, A. A. Long; Department of Rheumatology, Allergy & Immunology, MGH, Boston, MA.

1210   CD8+CD60+ T Cells, Cells Expressing Epsilon Specific mRNA, Soluble CD23 (sCD23), and Th1/Th2 Cytokines In Cord Blood

T. A. Smith-Norowitz, K. B. Norowitz, S. Chice, V. Shah, M. Hagler, D. Walker, J. P. Brennan, H. G. Durkin, M. H. Bluth; Center for Allergy and Asthma Research at SUNY Downstate Medical Center, Brooklyn, NY.

1211   Rhinovirus Infection in Lower Airways of Asthmatic Patients

M. Woś¹, M. Sanak¹, L. Burchell², A. G. Mosser², J. Soja¹, H. Olechnowicz³, A. T. Szczeklik ¹, W. W. Busse²; ¹Department of Medicine, Jagiellonian University School of Medicine, Krakow, POLAND, ²Division of Allergy and Immunology, Department of Medicine, University of Wisconsin-Madison, Madison, WI, ³Cracow's Thoracosurgery Hospital, Krakow, POLAND.

1212   The Role of Innate Immunity in Suppression of Allergic Inflammation by Ascaris Suum Antigens

A. Boesen ¹, B. Wetzel¹, H. Norris¹, V. Bundoc¹, J. Urban¹, J. Urban², A. Keane-Myers¹; ¹Niaid/lad/ais, National Institutes of Health, Rockville, MD, ²United States Department of Agriculture, Beltsville, MD.

1213   Mycobacterial Products Augment Ragweed Induced Allergic Airway Inflammation

N. G. Dharajiya, S. Sur; Internal Medicine, University TX Medical Branch, Galveston, TX.

1214   Th2 Cytokine and Chemokine are Elevated In Nasopharyngeal Secretions of Pediatric Patients with RSV Infection

H. Murai ¹, A. Terada², H. Togari¹; ¹Pediatrics, Nagoya City University School Of Medicine, Nagoya, Aichi, JAPAN, ²Pediatric allergy, Daido Hospital, Nagoya, Aichi, JAPAN.

1215   Virus Detection, Cytokine Response Profiles, and Eosinophil Activation in Acute Exacerbation of Childhood Asthma

M. Kato ¹, M. Saitoh², H. Tsukagoshi², K. Maruyama³, Y. Hayashi⁴, K. Kozawa², H. Kimura²; ¹Allergy and Immunology, Gunma Children's Medical Center, Hokkitsu, Gunma, JAPAN, ²Gunma Prefectural Institute of Public Health and Environmental Sciences, Maebashi, Gunma, JAPAN, ³Internal Medicine, Gunma Children's Medical Center, Hokkitsu, Gunma, JAPAN, ⁴Hematology and Oncology, Gunma Children's Medical Center, Hokkitsu, Gunma, JAPAN.

1216   Toll-like Receptor 3 and Chemokine Synthesis in Human Bronchial Smooth Muscle Cells

K. Niimi, K. Asano, Y. Shiraishi, T. Takihara, J. Kagyo, M. Wakaki, T. Nakajima, Y. Suzuki, T. Shiomi, T. Oguma, A. Ishizaka; Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, JAPAN.

Poster Session

5212

Tuesday, March 07, 2006

9:45 am to 10:45 am

Innate Immunity and Virus Infections

1217   Oral Treatment with Live Lactobacillus Reuteri Attenuates the Allergic Airway Response in Mice

P. Forsythe ¹, J. Wattie², M. Inman², J. Bienenstock¹; ¹Brain Body Institute and Department of Pathology and Molecular Medicine, McMaster University and St Joseph's Healthcare, Hamilton, ON, CANADA, ²Firestone Institute for Respiratory Health, McMaster University and St Joseph's Healthcare, Hamilton, ON, CANADA.

1218   Wheezing with Rhinovirus but not Respiratory Syncytial Virus Infections in the First Three Years of Life Predicts Decreased Lung Function at Age Five

T. E. Pappas ¹, M. D. Evans², K. T. Sullivan Dillie¹, K. A. Roberg¹, D. F. DaSilva¹, C. J. Tisler¹, E. L. Anderson¹, L. E. Pleiss¹, R. Gangnon², J. E. Gern³, R. F. Lemanske, Jr.³; ¹Department of Pediatrics, University of Wisconsin - Madison, Madison, WI, ²Department of Biostatistics and Medical Informatics, University of Wisconsin - Madison, Madison, WI, ³Department of Medicine, University of Wisconsin - Madison, Madison, WI.

1219   The Influence of Eosinophilic Airway Inflammation in Response to Double-Stranded RNA Instillation

Y. Shiraishi ^1,2, K. Asano^1,2, K. Niimi^1,2, M. Wakaki^1,2, J. Kagyo^1,2, T. Takihara^1,2, K. Sayama¹, T. Nakajima¹, T. Oguma¹, Y. Suzuki¹, T. Shiomi¹, E. Ikeda³, A. Ishizaka^1,2; ¹Division of Pulmonary Medicine, Department of Medicine, Keio University, Tokyo, JAPAN, ²Pfizer-Keio Research Laboratories, Tokyo, JAPAN, ³Department of Pathology, Keio University, Tokyo, JAPAN.

1220   Increased Tumor Necrosis Factor-a and Endothelin-1 in Nasal Secretion of Infants with Respiratory Syncytial Virus Bronchiolitis

H. Chung, S. Kim; Pediatrics, School of Medicine, Catholic University of Taegu, Taegu, REPUBLIC OF KOREA.

1221   Human Bronchoalveolar (BAL) Cells Secrete Increased Amounts of Monocyte Chemoattractant Protein 1 (MCP-1) During an Experimental Rhinovirus (RV) Infection

M. Bates ¹, N. L. Korpi¹, D. J. Hall², R. L. Heuser¹, M. Aga¹, W. W. Busse³, P. J. Bertics¹; ¹Biomolecular Chemistry, University of Wisconsin, Madison, WI, ²Chemistry, Lawrence University, Appleton, WI, ³Medicine, University of Wisconsin, Madison, WI.

1222   Rhinovirus (RV)-Stimulated Release of Interferon γ-Inducible Protein 10 (IP-10) by Human Monocytes and Alveolar Macrophages

N. L. Korpi ¹, M. Bates¹, D. J. Hall², P. J. Bertics¹; ¹Biomolecular Chemistry, University of Wisconsin Madison, Madison, WI, ²Chemistry, Lawrence University, Appleton, WI.

1223   C57BL6 not Balb/c Mice Develop Enhanced Ova-Specific IgE after Paramyxomal Viral Infection

U. Kaza, M. M. Rohlfing, M. H. Grayson; Division of Allergy and Immunology, Washington University School of Medicine, St. Louis, MO.

1224   Increased BAL Levels of Surfactant Protein (SP)-D in a Transgenic Mouse Model of Allergic Bronchopulmonary Aspergillosis

S. L. Koehm ¹, P. S. Hutcheson², S. Kierstein³, C. J. Bellone¹, A. Haczku³, R. G. Slavin²; ¹Molecular Microbiology & Immunology, Saint Louis University School of Medicine, Saint Louis, MO, ²Internal Medicine/Allergy & Immunology, Saint Louis University School of Medicine, Saint Louis, MO, ³University of Pennsylvania School of Medicine, Philadelphia, PA.

1225   FcεR1 and Toll-Like Receptors Mediate Synergistic Signals to Markedly Augment Production of Inflammatory Cytokines in Murine Mast Cells

H. Qiao ¹, M. A. Beaven²; ¹Lab of Molecular Immunology, National Heart, Lung and Blood Institute, Bethesda, MD, ²Lab. of Molecular Immunology, National Heart, Lung and Blood Institute, Bethesda, MD.

1226   Pulmonary and Systemic Responses to Inhaled Allergens are Aggravated by Inhaled Endotoxin

K. Kulhankova ¹, C. S. George², J. N. Kline^3,1, P. S. Thorne¹; ¹Occupational & Environmental Health, College of Public Health, University of Iowa, Iowa City, IA, ²Pediatrics, College of Medicine, University of Iowa, Iowa City, IA, ³Internal Medicine, College of Medicine, University of Iowa, Iowa City, IA.

1227   (R)-, But Not (S)-, Enantiomers of Beta2 Agonists Inhibit IL-8 Secretion by RSV Antigen-Stimulated Confluent HumanAlveolar Epithelial Cells (cA549)

M. Frieri, A. Capetandes; Division of Allergy Immunology, Nassau University Medical Center, East Meadow, NY.

1228   Association Between TGF-B1 Genotype and the Development of Otitis Media (OM) in Young Children during Respiratory Virus Season

A. Patel, D. A. Gentile, J. Koehrsen, D. P. Skoner; Department of Pediatrics, Allegheny General Hospital, Pittsburgh, PA.

1229   The Influence of Daycare, Older Siblings and Wheezing Respiratory Illnesses During Infancy on the Development of Allergic Sensitization

D. F. G. DaSilva ¹, M. D. Evans², J. D. Bufford³, C. J. Tisler¹, K. A. Roberg¹, T. E. Pappas¹, E. L. Anderson¹, L. E. Pleiss¹, K. T. Sullivan Dillie¹, R. E. Gangnon², J. E. Gern³, R. F. Lemanske, Jr.³; ¹Department of Pediatrics, University of Wisconsin - Madison, Madison, WI, ²Biostatistics and Medical Informatics, University of Wisconsin - Madison, Madison, WI, ³Department of Medicine, University of Wisconsin - Madison, Madison, WI.

1230   Comparisons of Cytokine Expression and Nuclear Factor-kB Activation between Respiratory Syncytial Virus Infected and Adenovirus Infected Human Bronchial Epithelial Cells

J. Yoon, M. Lee, H. Kim, J. Kim, J. Lee; Department of pediatrics, the Catholic University of Korea, Seoul, REPUBLIC OF KOREA.

Poster Session

5213

Tuesday, March 07, 2006

9:45 am to 10:45 am

Rhinosinusitis: Treatment

1231   Azelastine Nasal Spray Compared to Cetirizine in the Treatment of Patients with Seasonal Allergic Rhinitis: a Pooled Analysis of Two Double-Blind, Multicenter Studies

E. Sher ¹, H. Sacks²; ¹Atlantic Allergy Asthma and Immunology Associates, Ocean, NJ, ²MedPointe Pharmaceuticals, Somerset, NJ.

1232   Effects of the Novel Intranasal Glucocorticosteroid Gw685698 (200μG Once-daily) on Seasonal Allergic Rhinitis (sar) Symptoms Induced in the Vienna Challenge Chamber Model (vcc)

P. Stuebner; ENT University Clinic, Vienna, AUSTRIA.

1233   Effects of Levocetirizine on Symptoms and Quality of Life in Persistent Allergic Rhinitis and Comorbid Asthma

G. Passalacqua, M. Pasquali, A. Rogkakou, I. Baiardini, A. Riccio, C. Gamalero, G. Canonica; Allergy & Respiratory Diseases Dept of Internal Medicine, Genoa University, Genova, ITALY.

1234   High Affinity Histamine Binding Protein Attenuates Nasal Allergen Challenge Induced Allergic Rhinitis

W. H. Weston-Davies ¹, P. H. Ratner², C. P. Andrews³, G. C. Paesen⁴, P. A. Nuttall⁴; ¹Evolutec Group plc, Reading, UNITED KINGDOM, ²Sylvana Research Associates, San Antonio, TX, ³Diagnostics Research Group, San Antonio, TX, ⁴Centre for Ecology and Hydrology, Natural Environment Research Council, Oxford, UNITED KINGDOM.

1235   Evaluation of Nasal Patency and Nasal Nitric Oxide Levels in Subjects with Allergic Rhinitis After Pharmacologic or Physiologic Stimuli: a Two Parallel Groups Study

C. D. Serrano ¹, A. L. Valero², J. Bartra², A. Torrego², J. Mullol³, C. Picado²; ¹Allergy Unit, Fundación Clínica Valle del Lili, Cali, COLOMBIA, ²Pneumology and Respiratory Allergy Departament, Hospital Clínic, Barcelona, SPAIN, ³Rhinology Unit, ENT Departament, Hospital Clínic, Barcelona, SPAIN.

1236   Desloratadine is Safe and Effective in the Treatment of the Nasal Symptoms of Perennial Allergic Rhinitis (PAR): Results of Two Observational Studies

M. Montagne ¹, C. Gennaro², M. Bouchard³, D. Flores⁴, G. Hernández⁵, E. Urdaneta⁶; ¹Centro Policlínico Valencia, Valencia, VENEZUELA, ²Centro Médico Maracay, Maracay, VENEZUELA, ³Instituto de Inmunología de la Universidad de los Andes, Mérida, VENEZUELA, ⁴Instituto Clínico Unare, Bolívar, VENEZUELA, ⁵Hospital Universitario de Caracas, Caracas, VENEZUELA, ⁶Schering-Plough, Caracas, VENEZUELA.

1237   Desloratadine for the Relief of Nasal and Non-Nasal Allergic Symptoms: an Observational Study

W. Aberer; Dermatologic University Clinic Graz, Austria, Graz, AUSTRIA.

1238   Desloratadine is Effective in Relieving the Nasal and Non-Nasal Symptoms of Perennial Allergic Rhinitis (PAR) in Patients With or Without Concurrent Respiratory Tract Conditions

C. Loureiro ¹, C. Chieira¹, M. A. P. Guilherme², A. Arrobas³, G. Castelo Branco⁴, F. Inácio⁵, P. L. Pinto⁶, A. Afonso⁷, M. Branco⁸, F. D. Borges⁹, M. Trindade¹⁰; ¹Hospitais da Universidade de Coimbra, Coimbra, PORTUGAL, ²Centro Hospitalar de Vila Nova de Gaia., Gaia, PORTUGAL, ³Centro Hospitalar de Coimbra, Coimbra, PORTUGAL, ⁴Hospital de S.João, Porto, PORTUGAL, ⁵Hospital de S. Bernardo, Setúbal, PORTUGAL, ⁶Hospital D.Estefânia, Lisboa, PORTUGAL, ⁷Hospital de S.Pedro, Vila Real, PORTUGAL, ⁸Hospital de Santa Maria, Lisboa, PORTUGAL, ⁹Centro Hospitalar do Funchal, Funchal, PORTUGAL, ¹⁰Hospital Pulido Valente, Lisboa, PORTUGAL.

1239   Azelastine Nasal Spray is Safe and Effective at a Dosage of 1 Spray per Nostril Twice Daily in Patients with Seasonal Allergic Rhinitis (SAR)

W. Lumry ¹, W. Wheeler²; ¹Allergy and Asthma Research, Dallas, TX, ²MedPointe Pharmaceuticals, Somerset, NJ.

Poster Session

5214

Tuesday, March 07, 2006

9:45 am to 10:45 am

Rhinosinusitis: Quality of Life and Epidmiology

1240   Rhinitis Symptom Sufferers Report a Significant Symptom Burden During an Allergy Season

R. Stanford ¹, E. Meltzer², J. Derebery³, R. Nathan⁴, U. Campbell⁵, P. Stang⁵; ¹GlaxoSmithKline, Research Triangle Park, NC, ²Allergy and Asthma Medical Group and Research Center, San Diego, CA, ³House Ear Clinic, Los Angeles, CA, ⁴Asthma & Allergy Associates and Research Center, Colorado Springs, CA, ⁵Galt Associates, Blue Bell, PA.

1241   Infrequent Treatment of Symptoms Among Rhinitis Symptom Sufferers During an Allergy Season

P. Stang ¹, E. Meltzer², J. Derebery³, R. Nathan⁴, U. Campbell¹, R. H. Stanford⁵; ¹Galt Associates, Blue Bell, PA, ²Allergy and Asthma Medical Group and Research Center, San Diego, CA, ³House Ear Clinic, Los Angeles, CA, ⁴Asthma & Allergy Associates and Research Center, Colorado Springs, CO, ⁵GlaxoSmithKline, Research Triangle Park, NC.

1242   Measurement of Nitric Oxide (no) as a Tool in the Diagnosis of a Child with Recurrent Pneumonias

M. J. Lanz ¹, C. M. Ferrer², M. Laufer³; ¹Allergy and Immunology, AAADRS Research Center and Miami Childrens Hospital, Coral Gables, FL, ²Allergy and Asthma, AAADRS Research Center, Coral Gables, FL, ³Pediatric Infectious Disease, Miami Childrens Hospital, Miami, FL.

1243   Allergic Rhinitis (AR) and its Impact on Cost, Productivity and Healthcare Resource Use of Patients

Y. S. Punekar ¹, R. D. O'Connor²; ¹GlaxoSmithKline, Greenford, UNITED KINGDOM, ²Sharp Rees-Stealy Medical Group, San Diego, CA.

1244   Assessing Symptomatic Burden of Patients Suffering from Allergic Rhinitis (AR)

R. D. O'Connor¹, Y. S. Punekar²; ¹Department of Quality Management, Sharp Rees-Stealy Medical Group, San Diego, CA, ²Global Health Outcomes, GlaxoSmithKline, London, UNITED KINGDOM.

1245   Heterogeneity of Effects in the Appearance of Rhinitis or/and Asthma According to Age and Atopy

A. Rosado, M. Tejedor, M. Moro, C. Vila, M. Fernández-Rivas, M. Mugica, M. D. Alonso, T. Verdura; Unidad de alergia, FUNDACION HOSPITAL ALCORCON, ALCORCON, SPAIN.

1246   Great Comorbidity Burden Related to Rhinitis Symptom Sufferers

R. A. Nathan ¹, J. Derebery², E. Meltzer³, P. Stang⁴, U. Campbell⁴, R. H. Stanford⁵; ¹Asthma & Allergy Associates and Research Center, Colorado Springs, CO, ²House Ear Clinic, Los Angeles, CA, ³Allergy and Asthma Medical Group and Research Center, San Diego, CA, ⁴Galt Associates, Blue Bell, PA, ⁵GlaxoSmithKline, Research Triangle Park, NC.

1247   Seasonal Rhinoconjnctivitis in a Farner. A Case Report

A. Moreno ¹, J. Ruiz², J. Mira¹; ¹allergy, Hospital Virgen de la Luz, Cuenca, SPAIN, ²allergy, Hospital Gregorio Marañon, Madrid, SPAIN.

1248   Another Good Reason to Live in Cleveland, Ohio

A. E. Varner; Allergy Diagnostic, Beachwood, OH.

1249   Azelastine Nasal Spray Significantly Improves Health-Related Quality of Life Compared to Cetirizine Tablets in Patients with Seasonal Allergic Rhinitis (SAR)

E. O. Meltzer ¹, H. Sacks²; ¹Allergy & Asthma Medical Group & Research Center, A.P.C, San Diego, CA, ²MedPointe Pharmaceuticals, Somerset, NJ.

Oral Abstract Session

5601

Tuesday, March 07, 2006

2:00 pm to 3:15 pm

Genetics

1250   Further Evidence for Asthma Susceptibility Gene on Chromosome 11 in African Americans

P. S. Gao ¹, R. A. Mathias², J. Goldstein, Sr.³, W. Alexander F², E. W. Pugh³, A. Togias¹, K. C. Barnes¹, T. Beaty⁴, S. K. Huang¹; ¹Johns Hopkins School of Medicine, Baltimore, MD, ²Inherited Disease Research Branch, NIH, Baltimore, MD, ³Center for Inherited Disease Research, Baltimore, MD, ⁴Johns Hopkins University Bloomberg School of Medicine, Baltimore, MD.

1251   Genetic Association Study Between Asthma and Plasma IgE and Human Beta-Defensin-1 Gene in Chinese Children

T. F. Leung ¹, C. Y. Li¹, C. W. K. Lam², N. L. S. Tang², G. W. K. Wong¹; ¹Department of Pediatrics, The Chinese University of Hong Kong, Hong Kong, HONG KONG SPECIAL ADMINISTRATIVE REGION OF CHINA, ²Department of Chemical Pathology, The Chinese University of Hong Kong, Hong Kong, HONG KONG SPECIAL ADMINISTRATIVE REGION OF CHINA.

1252   CTLA-4 Exon 1 and Promoter Gene Polymorphisms in Childhood Asthma

H. Yang ¹, J. Shin¹, K. Kim¹, C. Kim², M. Sohn¹, K. Kim¹; ¹Pediatrics, Sinchon Severance, Seoul, REPUBLIC OF KOREA, ²Pediatrics, Kwandong university, Seoul, REPUBLIC OF KOREA.

1253   Involvement of Il-10 Gene Promoter Polymorphisms in the Susceptibility for Childhood Asthma

M. Sohn, H. Yang, K. Kim; Department of Pediatrics, Yonsei University College of Medicine, Seoul, REPUBLIC OF KOREA.

Oral Abstract Session

5602

Tuesday, March 07, 2006

2:00 pm to 3:15 pm

Primary and Secondary Immunodeficiency

1254   Natural Killer T (NKT) Cell Development in Severe Combined Immunodeficiency (SCID) After T Cell Depleted Haploidentical Bone Marrow Transplantation (BMT)

E. O. Sajaroff, R. H. Buckley; Pediatric, Allergy and Immunology, Duke University Medical Center, Durham, NC.

1255   Microfluidic Device Allows Low-Cost Newborn Screening for Severe Combined Immune Deficiency (SCID)

M. J. Butte ^1,2, A. P. Wong^3,4, A. Sridhar⁵, A. H. Sharpe², G. M. Whitesides⁴; ¹Division of Immunology, Children's Hospital Boston, Boston, MA, ²Pathology, Harvard Medical School, Boston, MA, ³Biophysics Graduate Group, Harvard University, Boston, MA, ⁴Chemistry and Chemical Biology, Harvard University, Boston, MA, ⁵Summer Research Internship, Boston University, Boston, MA.

1256   Epigallocatechin Gallate, Green Tea Catechin, Binds to the T Cell Receptor, CD4

C. L. Nance ^1,2, M. P. Williamson³, T. G. McCormick¹, S. M. Paulson¹, W. T. Shearer^1,2; ¹Baylor College of Medicine, Houston, TX, ²Texas Children's Hospital, Houston, TX, ³University of Sheffield, Sheffield, UNITED KINGDOM.

1257   Cell-Cell Interactions and Cell Fate Determination: Involvement of Dlk in B Cell Developmentand Function

r. raghunandan, E. Rudikoff, S. Bauer; Laboratory of Stem cell biology, CBER, FDA, Bethesda, MD.

Oral Abstract Session

5603

Tuesday, March 07, 2006

2:00 pm to 3:15 pm

Recent Advances in Vaccine Therapy

1258   Positive Phase IIa Data of CYT005-AllQbG10, a Novel Vaccine for Treatment of Allergic Rhinitis and Asthma

T. M. Kuendig ¹, P. Mueller², G. Senti¹; ¹University of Zurich, Zurich, SWITZERLAND, ²Cytos Biotechnology, Zurich, SWITZERLAND.

1259   Chemical Modification of Birch Allergen Extract Leads to a Reduction in Allergenicity as well as Immunogenicity

P. A. Würtzen, G. Lund, L. Lund, K. Lund, H. Henmar; Experimental Immunology, ALK-Abello, Hørsholm, DENMARK.

1260   Quality of Life in Specific Immunotherapy with Alutard Sq^® Grass Pollen in Allergic Rhinoconjuntivitis - The Ukis-Study Results

T. Krishna ¹, A. Frew², S. Durham³; ¹Birmingham Heartlands Hospital, W. Midlands, Birmingham, UNITED KINGDOM, ²Southamton General Hospital, Southampton, UNITED KINGDOM, ³Imperial College National Heart & Lung Institute, London, UNITED KINGDOM.

1261   Peptide Immunotherapy in Fel d 1-Sensitized HLA-DR1 Transgenic Mice is Associated with Increased IL-10 but Independent of TGFbeta and Foxp3 Expression

D. Campbell ¹, H. Gronlund², M. van Hage-Hamsten², D. M. Altmann³, C. M. Lloyd¹, M. Larché⁴; ¹Leukocyte Biology Section, Imperial College London, London, UNITED KINGDOM, ²Department of Medicine, Karolinska Institutet, Stockholm, SWEDEN, ³Infectious Diseases Department, Imperial College London, London, UNITED KINGDOM, ⁴Allergy & Clinical Immunology, Imperial College London, London, UNITED KINGDOM.

Oral Abstract Session

5604

Tuesday, March 07, 2006

2:00 pm to 3:15 pm

Food Allergy

1262   Oral Desensitization and Induction of Tolerance in Peanut-Allergic Children

A. Buchanan ¹, A. M. Scurlock^2,3, S. M. Jones^2,3, L. Christie^2,3, K. M. Althage^2,3, L. Pons¹, P. H. Steele¹, A. W. Burks¹; ¹Duke University Medical Center, Durham, NC, ²Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, ³Arkansas Children's Hospital, Little Rock, AR.

1263   Comparison of Efficacy of a Novel Probiotic from Koji Fermentation(ImmuSoy) with LGG on Peanut Allergy

W. PAN ¹, T. ZHANG², M. TAKEBE³, H. A. SAMPSON², X. LI²; ¹Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA, ²Pediatrics, Allergy & Immunology, Mount Sinai School of Medicine, New York, NY, ³Biotics R&D Division, NICHIMO CO., LTD, Tokyo, JAPAN.

1264   Silencing Peanut Allergy: A Chinese Herbal Formula, Fahf-2, Completely Blocks Peanut-induced Anaphylaxis for up to 6 Months Following Therapy in a Murine Model Of Peanut Allergy

K. D. Srivastava, T. Zhang, C. Qu, H. A. Sampson, X. M. Li; Graduate School of Biological Sciences, Mount Sinai School of Medicine, New York, NY.

1265   Breeding a Hypoallergenic Peanut

T. Perkins ¹, D. A. Schmitt¹, T. G. Isleib², H. Cheng¹, S. J. Maleki¹; ¹Food Allergy Unit, USDA-Agricultural Research Service, New Orleans, LA, ²Department of Crop Science, NCSU, Raleigh, NC.

Oral Abstract Session

5606

Tuesday, March 07, 2006

2:00 pm to 3:15 pm

Control of Allergic Inflammation

1266   A Novel CCR3-CD300a Bispecific Antibody Fragment Reverses Airway Inflammation and Tissue Remodeling in a Model of Established-Chronic Experimental Asthma

A. Munitz, I. Bachelet, F. Levi-Schaffer; Hebrew University Of Jerusalem, Jerusalem, ISRAEL.

1267   Cysteinyl Leukotrienes in a Murine Model of Allergic Pulmonary Inflammation

F. I. Hsu, D. C. Kim, N. A. Barrett, D. S. Friend, K. F. Austen, Y. Kanaoka; Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA.

1268   In Vivo Depletion of Murine Eosinophils by Antibodies to Siglec-F

N. Zimmermann ¹, M. McBride¹, Y. Yamada¹, A. Raper², P. R. Crocker², M. E. Rothenberg¹, B. S. Bochner³; ¹Allergy and Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Division of Cell Biology and Immunology, The Wellcome Trust Biocentre at Dundee, Dundee, UNITED KINGDOM, ³Allergy and Clinical Immunology, Johns Hopkins University School of Medicine, Baltimore, MD.

1269   A Central Regulatory Role for Eosinophils and the Eotaxin/CCR3 Axis in Chronic Experimental Asthma

P. C. Fulkerson ^1,2, C. A. Fischetti¹, S. P. Hogan¹, M. E. Rothenberg^1,2; ¹Division of Allergy & Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²University of Cincinnati College of Medicine, Cincinnati, OH.

Oral Abstract Session

5607

Tuesday, March 07, 2006

2:00 pm to 3:15 pm

Immunotherapy Mechanisms

1270   Immunological Response to Administration of Standardized Dog Allergen Extract at Differing Doses

A. M. Lent, R. Harbeck, M. Sills, K. Schmidt, B. Efaw, T. Lebo, H. S. Nelson; Allergy and Immunology, National Jewish Medical and Research Center, Denver, CO.

1271   T-cells Apoptosis induced by Allergens

J. Fernandez ¹, J. M. García¹, J. Carreton¹, A. Esteban²; ¹Allergy Sect. Clinical Medicine., Elche U. Hospital. Miguel Hernández University, Elche Alicante, SPAIN, ²Biochemical laboratory, Alicante U. Hospital., Alicante, SPAIN.

1272   Induction of IL-10 Occurs Early and Precedes Serum IgG Blocking Activity During a Cluster Regimen of Grass Pollen Immunotherapy

L. K. Wilcock ¹, J. N. Francis², G. Paraskavopoulos², S. J. Till², S. R. Durham²; ¹National Heart and Lung Institute, Imperial College, London, UNITED KINGDOM, ²Allergy and Clinical Immunology, Imperial College, London, London, UNITED KINGDOM.

1273   Validation of a Functional Assay of IgE-Facilitated CD23-Dependent Allergen Binding to B Cells to Monitor Clinical Efficacy of Immunotherapy

M. H. Shamji ¹, L. K. Wilcock², M. Larche², J. N. Francis², S. R. Durham²; ¹National Heart and Lung Institute, Imperial College, London, UNITED KINGDOM, ²Allergy and Clinical Immunology, Imperial College, London, London, UNITED KINGDOM.