Skip to main content
Elsevier - PMC COVID-19 Collection logoLink to Elsevier - PMC COVID-19 Collection
. 2003 Aug 27;1(3):427–430. doi: 10.1016/0952-7915(88)90022-2

Immunity to viruses

A Zurbriggen 1, RS Fujinami 1
PMCID: PMC7134739  PMID: 2508700

The content is available as a PDF (677.3 KB).

References

  • 1.Colman P.M., Air G.M., Webster R.G., Varghese J.N., Baker A.T., Lentz M.R., Tulloch P.A., Laver W.G. How antibodies recognize virus proteins. Immunol Today. 1987;8:323–326. doi: 10.1016/0167-5699(87)90004-1. Of interest. [DOI] [PubMed] [Google Scholar]; The 3-dimensional structure of a monoclonal antibody Fab fragment bound to influenza virus neuraminidase is reviewed. Antigenic epitopes are localized surface loops.
  • 2.Weis W., Brown J.H., Cusak S., Paulson J.C., Skehel J.J., Wiley D.C. Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid. Nature. 1988;333:426–431. doi: 10.1038/333426a0. Of interest. [DOI] [PubMed] [Google Scholar]; The 3-dimensional structure of influenza virus hemagglutinin strengthens our understanding of virus receptors and virus neutralization.
  • 3.Page G.S., Mosser A.G., Hogle J.M., Filman D.J., Rueckert R.R., Chow M. Three-dimensional structure of poliovirus serotype 1 neutralizing determinants. J Virol. 1988;62:1781–1794. doi: 10.1128/jvi.62.5.1781-1794.1988. Of outstanding interest. [DOI] [PMC free article] [PubMed] [Google Scholar]; 63 antigenic poliovirus mutants are characterized. An interesting mechanism of how virus escapes neutralization is discussed.
  • 4.Leist T.P., Cobbold S.P., Waldmann H., Aguet M., Zinkernagel R.M. Functional analysis of T lymphocyte subsets in antiviral host defense. J Immunol. 1987;138:2278–2281. Of interest. [PubMed] [Google Scholar]; The function: of T lymphocytes in LCMV infection is examined.
  • 5.Ahmed R., Butler L.D., Bhatti L. T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T cell and antibody responses. J Virol. 1988;62:2102–2106. doi: 10.1128/jvi.62.6.2102-2106.1988. Of outstanding interest. [DOI] [PMC free article] [PubMed] [Google Scholar]; LCMV specific CTL response can be produced even with a deficiency of T helper cells. This has a more severe effect on antibody production, rather than on the cellular immune response.
  • 6.Wraith D.C. The recognition of influenza—A virus-infected cells by cytotoxic T lymphocytes. Immunol Today. 1987;8:239–246. doi: 10.1016/0167-5699(87)90174-5. Of interest. [DOI] [PubMed] [Google Scholar]; A review on T cell functions after influenza virus infection.
  • 7.Brown L.E., Katz J.M., French R.A., Anders E.M., White D.O. Characterization of subtype-specific and cross-reactive helper-T cell clones recognizing influenza virus hemagglutinin. Cell Imunol. 1987;109:12–24. doi: 10.1016/0008-8749(87)90288-7. Of interest. [DOI] [PubMed] [Google Scholar]; T helper cells stimulated by influenza virus HA may provide a basis for a rapid memory response.
  • 8.Lightman S., Cobbold S.P., Waldmann H., Askonas B.A. Do L3T4+ T cells act as effector cells in protection against influenza virus infection. Immunology. 1987;62:139–144. Of interest. [PMC free article] [PubMed] [Google Scholar]; Cytotoxic T cells are more efficient in influenza virus clearance than T helper cells.
  • 9.Liebert U.G., Linington C., ter Meulen V. Induction of autoimmune reactions to myelin basic protein in measles virus encephalitis in Lewis rats. J Neuroimmunol. 1988;17:103–118. doi: 10.1016/0165-5728(88)90018-5. Of interest. [DOI] [PMC free article] [PubMed] [Google Scholar]; Myelin basic protein-specific T cell clones from rats with subacute measles encephalitis do not cross-react with measles virus and their adoptive transfer can induce EAE.
  • 10.Cannon M.J., Stott E.J., Taylor G., Askonas B.A. Clearance of persistent respiratory syncytial virus infections in immunodeficient mice following transfer of primed T cells. Immunology. 1987;62:133–138. Of interest. [PMC free article] [PubMed] [Google Scholar]; RSV can be cleared by 2 different immune mechanisms depending on the stage of the infection.
  • 11.Thorley-Lawson D.A., Israelsohn E.S. Vol. 84. 1987. Generation of specific cytotoxic T cells with a fragment of the Epstein-Bart virus-encoded p63/latent membrane protein; pp. 5384–5388. (Proc Natl Acad Sci USA). Of interest. [DOI] [PMC free article] [PubMed] [Google Scholar]; A 10-amino acid long peptide can induce Epstein-Bart virus specific CTL and therefore contains an eptiope for T cell recognition.
  • 12.Bjorkman P.J., Saper M.A., Samraqui B., Bennett W.S., Strominger J.L, Wiley D.C. Structure of the human class I histocompatibility antigen, HLA-A2. Nature. 1987;329:506–511. doi: 10.1038/329506a0. Of outstanding interest. [DOI] [PubMed] [Google Scholar]; The 3-dimensional structure of HLA molecules has long been sought, in order to develop specific insight into the antigen and T cell recognition properties of these molecules.
  • 13.Suzumura A., Lavi E., Bhat S., Murasko D., Weiss S.R., Silberberg D.H. Induction of glial cell MHC antigen expression in neurotropic coronavirus infections: characterization of the H-2-inducing soluble factor elaborated by infected brain cells. J Immunol. 1988;140:2068–2072. Of interest. [PubMed] [Google Scholar]; MHC class I expression can be induced on the surface of glial cells by neurotropic coronavirus.
  • 14.Chu C.-M., Shyu W.-C., Kuo R.-W., Liaw Y.-F. HLA class I antigendisplay on hepatocyte membrane in chronic hepatitis B virus infection: its role in the pathogenesis of chronic type B hepatitis. Hepatology. 1987;7:1311–1316. doi: 10.1002/hep.1840080358. Of interest. [DOI] [PubMed] [Google Scholar]; Chronic hepatitis B virus infection leads to expression of HLA class I antigen on hepatocytes and cytotoxic T cells are HLA class I antigen restricted.
  • 15.Todd J.A., Acha-Orbea H., Bell J.I., Chao N., Fronek Z., Jacob C.O., McDermott M., Sinha A.A., Timmerman L., Steinman L. A molecular basis for MHC class II-associated autoimmunity. Science. 1988;240:1003–1009. doi: 10.1126/science.3368786. Of outstanding interest. [DOI] [PubMed] [Google Scholar]; Class II MHC and their immunoregulatory role is explained on a molecular level.
  • 16.Gehrz R.C., Fuad S., Liu Y.-N.C., Bach F.H. HLA class II restriction of T helper cell response to cytomegalovirus (CMV). I. Immunogenetic control of restriction. J Immunol. 1987;138:3145–3151. Of interest. [PubMed] [Google Scholar]; All 3 HLA class II families are involved in cytomegalovirus recognition.
  • 17.Query C.C., Keene J.D. A human autoimmune protein associated with Ul RNA contains a region of homology that is cross-reactive with a retroviral P30gag antigen. Cell. 1987;51:211–220. doi: 10.1016/0092-8674(87)90148-6. Of interest. [DOI] [PubMed] [Google Scholar]; A sequence homology between the small nuclear RNP autoantigen and a retrovirus protein enhances the importance of retroviruses for autoimmune diseases.
  • 18.Rhodes G., Rumpold H., Kurki P., Patrick K.M., Carson D.A., Vaughan J.H. Autoantibodies in infectious mononucleosis have specificity for the glycine-alanine repeating region of the Epstein-Bart virus nuclear antigen. J Exp Med. 1987;165:1026–1040. doi: 10.1084/jem.165.4.1026. Of interest. [DOI] [PMC free article] [PubMed] [Google Scholar]; IgM autoantibodies produced during acute infectious mononucleosis recognize at least 10 cellular proteins.
  • 19.Neu N., Beisel K.W., Traystman M.D., Rose N.R., Craig S.W. Autoantibodies specific for the cardiac myosin isoform are found in mice susceptible to coxsackievirus B3-induced myocarditis. J Immunol. 1987;138:2488–2492. Of interest. [PubMed] [Google Scholar]; Mice strains susceptible to immunopathic myocarditis produce autoantibodies to the IgG class specific for cardiac myosin (genetic factors).
  • 20.Lodge P.A., Herzum M., Olszewski J., Huber S.A. Coxsackievirus B-3 myocarditis: acute and chronic forms of the disease caused by different immunopathogenic mechanisms. Am J Pathol. 1987;128:455–463. Of interest. [PMC free article] [PubMed] [Google Scholar]; T cell depletion studies demonstrate that virus-induced autoimmunity depends not only on the virus strain, but also on the host genetic composition.
  • 21.Matossian-Rogers A., Dos Santos A., Festenstein H. Human cytotoxic T cells against measles virus-infected and myelin basic protein-coated targets are cross-reactive. Int Arch Allergy Appl Immunol. 1987;84:159–164. doi: 10.1159/000234417. Of outstanding interest. [DOI] [PubMed] [Google Scholar]; Immunological cross-reaction leading to autoimmune events at the T cell level.

Articles from Current Opinion in Immunology are provided here courtesy of Elsevier

RESOURCES