Fig. 1.

Diagram of 3D MRF sequences. (a) Similar to the standard 2D MRF sequence, pseudorandom acquisition parameters, such as the flip angles (FA), were applied in the 3D MRF acquisition. (b) Standard 3D MRF sequence (3DMRF-S) with N time frames. A 2-sec waiting time was applied after data acquisition of each partition for partial longitudinal relaxation. (c) Modified 3D MRF sequence for acquiring training dataset for deep learning (3DMRF-DL). An extra section containing the pulse sequence for the first M time points was added at the beginning of the acquisition for each partition to simulate the spin history of the accelerated scan.