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. 2020 Apr 7;25(2):140–146. doi: 10.1007/s12204-020-2167-2

Prediction of COVID-19 Outbreak in China and Optimal Return Date for University Students Based on Propagation Dynamics

Ganyu Huang 1,#, Qiaoyi Pan 1,#, Shuangying Zhao 2,#, Yucen Gao 3, Xiaofeng Gao 3,
PMCID: PMC7137853  PMID: 32288415

Abstract

On 12 December 2019, a novel coronavirus disease, named COVID-19, began to spread around the world from Wuhan, China. It is useful and urgent to consider the future trend of this outbreak. We establish the 4+1 penta-group model to predict the development of the COVID-19 outbreak. In this model, we use the collected data to calibrate the parameters, and let the recovery rate and mortality change according to the actual situation. Furthermore, we propose the BAT model, which is composed of three parts: simulation of the return rush (Back), analytic hierarchy process (AHP) method, and technique for order preference by similarity to an ideal solution (TOPSIS) method, to figure out the best return date for university students. We also discuss the impacts of some factors that may occur in the future, such as secondary infection, emergence of effective drugs, and population flow from Korea to China.

Key words: epidemic dynamics model, nonlinear least squares; analytic hierarchy process (AHP); technique for order preference by similarity to an ideal solution (TOPSIS)

Nomenclature

c

The average number of contacts of an exposed person without isolation each day

n

The number of individuals

nD

The death toll

nE

The number of exposed individuals

nI

The number of infectious individuals

nR

The number of recovered individuals

nS

The number of susceptible individuals

N

The total population of China

p

Intensity of isolation for exposed individuals

r

Correlation coefficient

R2

Coefficient of determination

t0

Moment when the government began to take measures

t

Outbreak duration

α

Incubation rate

β

Infectious rate of contacts of an exposed person

γ

Recovery rate

μ

Pneumonia mortality

Footnotes

Foundation item: the National Key Research and Development Program of China (No. 2018YFB1004700), the National Natural Science Foundation of China (Nos. 61872238 and 61972254), the Shanghai Science and Technology Fund (No. 17510740200), and the CCFHuawei Database System Innovation Research Plan (No. CCF-Huawei DBIR2019002A)

These authors contributed equally to this work.

References

  • [1].Fan R G, Wang Y B, Luo M, et al. Journal of University of Electronic Science and Technology of China. 2020. SEIR-based novel pneumonia transmission model and inflection point prediction analysis [J] [Google Scholar]
  • [2].Geng H, Xu A D, Wang X Y, et al. Journal of Jinan University (Natural Science & Medicine Edition) 2020. Analysis of the role of current prevention and control measures in the epidemic of new coronavirus based on SEIR model [J] [Google Scholar]
  • [3].Zhou T, Liu Q H, Yang Z M, et al. Chinese Journal of Evidence-Based Medicine. 2020. Preliminary prediction of the basic reproduction number of the Wuhan novel coronavirus 2019-nCoV [J] [DOI] [PMC free article] [PubMed] [Google Scholar]
  • [4].Zhang L J, Wang F C, Zhuang X Q, et al. Global stability analysis on one type of SEIR epidemic model with floating population [J] Journal of Institute of Disaster Prevention. 2019;21(2):78–81. [Google Scholar]
  • [5].Read J M, Bridgen J R, Cummings D A T, et al. Novel coronavirus 2019-nCoV: Early estimation of epidemiological parameters and epidemic predictions [EB/OL] 2020. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • [6].Bai Y, Liu K, Chen Z J, et al. Early transmission dynamics of novel coronavirus pneumonia epidemic in Shaanxi Province [J] Chinese Journal of Nosocomiology. 2020;30(6):834–838. [Google Scholar]
  • [7].WU J T, LEUNG K, LEUNG G M. Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: A modelling study [J]. The Lancet, 2020. https://doi.org/10.1016/S0140-6736(20)30260-9 (published online).
  • [8].Li L J. Study on the stability of infectious disease dynamics model [D] Chengdu, China: University of Electronic Science and Technology of China; 2012. [Google Scholar]
  • [9].ZHANG F, LI L, XUAN H Y. Survey of transmission models of infectious diseases [J]. System Engineering: Theory and Practice, 2011, 31(9): 1736-1744 (in Chinese).
  • [10].Deng X, Li J M, Zeng H J, et al. Research on computation methods of AHP weight vector and its applications [J] Mathematics in Practice and Theory. 2012;42(7):93–100. [Google Scholar]
  • [11].Zhang J J. Fuzzy analytic hierarchy process [J] Fuzzy Systems and Mathematics. 2000;14(2):80–88. [Google Scholar]
  • [12].Yu X F, Fu D. A review of the comprehensive multi-index evaluation method [J] Statistics & Decision. 2004;15(11):119–121. [Google Scholar]
  • [13].Hu Y H. The improved method for TOPSIS in comprehensive evaluation [J] Journal of Mathematics in Practice and Theory. 2002;32(4):572–575. [Google Scholar]
  • [14].Mummert A, Otunuga O M. Parameter identification for a stochastic SEIRS epidemic model: Case study influenza[J] Journal of Mathematical Biology. 2019;79(2):705–729. doi: 10.1007/s00285-019-01374-z. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • [15].Ai L Z. Modelling the epidemic trend of the 2019-nCoV outbreak in Hubei Province, China [EB/OL] 2020. [Google Scholar]

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