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. 2020 Feb 14;39(15):3179–3194. doi: 10.1038/s41388-020-1207-6

Fig. 6. Dysregulated PTGES is inversely correlated with GPRC5A and CD8+ T lymphocyte infiltration in NSCLCs.

Fig. 6

a A subset of lung tumor and normal tissues were subjected to western blotting to examine the PTGES and GPRC5A protein levels (n = 21 pairs). b Western blotting scores of PTGES and GPRC5A from the tissues as indicated. c PTGES and GPRC5A expression patterns being highly negative correlated in the samples. d Representative staining of GPRC5A, PTGES and CD8 in lung carcinoma and peritumoral lung tissues of patients from tissue chip samples (n = 50 pairs). e IHC scores of GPRC5A, PTGES and CD8 from the tissue chip as indicated. f Representative images of human lung tissues chip including tumor and adjacent normal tissues stained with IHC for GPRC5A, PTGES and CD8. g Correlation expression analysis of PTGES, GPRC5A and CD8 in human lung tissues chip. ns, not significant; *p < 0.05; **p < 0.01; ***p < 0.001.