Table 1.
Fold change of the metabolite levels in liver. A fold change of >1.5 or <0.66 was considered qualitatively important. Significance levels tested by one-way ANOVA with Benjamini–Hochberg correction. Abbreviations: LFD, low-fat diet; HFD, High-fat diet.
| Metabolite | LFD | HFD |
|---|---|---|
| Acetate | 1.00 | 1.10 |
| Glucose | 1.00 | 1.27 |
| Pyruvate | 1.00 | 1.14 |
| Fumarate | 1.00 | 2.95* |
| cis-Aconitate | 1.00 | 0.83 |
| Citrate | 1.00 | 0.66 |
| Malate | 1.00 | 2.60 ** |
| Succinate | 1.00 | 1.65 * |
| Taurine | 1.00 | 0.89 |
| Oxaloacetate | 1.00 | 1.78 * |
| Oxoglutarate | 1.00 | 1.31 |
The false discovery rate-corrected q < 0.05 was considered significant: * q < 0.05, ** q < 0.01.