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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: Hypertension. 2020 Mar 23;75(5):1315–1324. doi: 10.1161/HYPERTENSIONAHA.120.14736

Figure 3.

Figure 3.

Maternal CAP treatment persistently lowers systolic blood pressure (SBP), mean arterial pressure (MAP), heart rate (HR) and autonomic balance in SHR male offspring. (A) Continuous treatment of CAP and maternal treatment with CAP lowered SBP in the 12-week-old SHR. (B) SCAP and OCAP treatment with CAP lowered MAP in the 12-week-old SHR. (C) Changes in HR in the control, continuous CAP and maternal CAP of SHR. (D) Continuous treatment of CAP and maternal treatment with CAP attenuated increased low frequency/high frequency (LF/HF) ratio in the SHR of 12-week old. OCAP, maternal treatment with captopril; SCAP, sustained treatment with captopril. n= 6–7 rats per group. Data are represented as mean ± SEM. * P<0.05; **P<0.01; ***P<0.001; ****P<0.0001 in one-way ANOVA followed by Tukey’s multiple comparison.