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. 2020 Feb 26;12(3):610. doi: 10.3390/nu12030610

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of 5-uRCK and ellagic acid (EA) on body and organ weights in rats fed a high-cholesterol diet (HCD). (A) Body weight was measured every week for eight weeks of general (NCD) or HCD diet supplemented with or without 5-uRCK, ellagic acid, or simvastatin. (Figure S2). (B) Body weight gain in hypercholesterolemic rats fed an HCD for eight weeks. (C) Effect of 5-uRCK and ellagic acid on organ (liver, kidney, and spleen) weight in hypercholesterolemic rats fed an HCD. (D) Comparison of liver, kidney, and spleen weight ratio after 5-uRCK, ellagic acid, or simvastatin treatment for five weeks. The liver, kidney, and spleen weight ratio is equal to the liver, kidney, and spleen wet weight/body weight × 100%. p values compared with controls (NCD group) are denoted as * p < 0.05. The results are expressed as the mean ± SD (n = 8).