Table 3.
WKY | SHR | |||
---|---|---|---|---|
Control | Control | Navy Bean | Black Bean | |
Hemodynamics | ||||
SBP (mmHg) 1 | ||||
Baseline | 153 ± 7 b | 197 ± 6 a | 181 ± 8 a | 187 ± 4 a |
Week 4 | 153 ± 4 b | 188 ± 5 a | 194 ± 7 a | 194 ± 5 a |
Week 8 | 142 ± 6 b | 184 ± 5 a | 199 ± 6 a | 199 ± 6 a |
DBP (mmHg) 1 | ||||
Baseline | 99 ± 4 b | 149 ± 7 a | 134 ± 8 a | 140 ± 5 a |
Week 4 | 103 ± 5 b | 140 ± 4 a | 145 ± 7 a | 142 ± 7 a |
Week 8 | 94 ± 4 b | 138 ± 4 a | 146 ± 9 a | 144 ± 7 a |
MAP (mmHg) 1 | ||||
Baseline | 116 ± 5 b | 165 ± 6 a | 149 ± 8 a | 155 ± 5 a |
Week 4 | 119 ± 4 b | 156 ± 4 a | 161 ± 7 a | 159 ± 6 a |
Week 8 | 110 ± 5 b | 153 ± 4 a | 163 ± 8 a | 162 ± 6 a |
HR (bpm) 2 | ||||
Baseline | 397 ± 7 | 436 ± 20 | 435 ± 20 | 375 ± 7 |
Week 8 | 387 ± 14 | 442 ± 22 | 423 ± 22 | 423 ± 16 |
HRV (bpm) 2 | ||||
Baseline | 153 ± 2 | 145 ± 5 | 147 ± 4 | 162 ± 3 |
Week 8 | 158 ± 4 | 145 ± 6 | 148 ± 5 | 147 ± 3 |
Femoral artery stiffness | ||||
PFV (cm/s) | ||||
Baseline | 26.4 ± 1.8 | 28.3 ± 0.6 | 27.6 ± 1.1 | 27.6 ± 0.9 |
Week 8 | 24.6 ± 1.3 | 27.9 ± 1.1 | 27.3 ± 1.9 | 27.7 ± 1.4 |
MinFV (cm/s) | ||||
Baseline | 1.60 ± 0.78 | 1.90 ± 1.10 | 3.32 ± 0.35 | 2.98 ± 0.54 |
Week 8 | 2.74 ± 0.32 | 3.25 ± 0.73 | 2.00 ± 0.76 | 3.85 ± 0.59 |
MFV (cm/s) | ||||
Baseline | 6.37 ± 0.59 b | 7.44 ± 0.88 a,b | 8.55 ± 0.44 a | 8.67 ± 0.48 a |
Week 8 | 6.85 ± 0.45 | 8.20 ± 0.79 | 7.30 ± 0.56 | 8.69 ± 0.72 |
Pulsatility index | ||||
Baseline | 4.2 ± 0.4 | 3.7 ± 0.6 | 2.9 ± 0.1 | 3.1 ± 0.3 |
Week 8 | 2.7 ± 0.4 | 3.0 ± 0.3 | 3.3 ± 0.2 | 3.2 ± 0.3 |
Resistivity index | ||||
Baseline | 0.94 ± 0.03 | 0.92 ± 0.03 | 0.88 ± 0.01 | 0.90 ± 0.02 |
Week 8 | 0.92 ± 0.02 | 0.88 ± 0.03 | 0.92 ± 0.03 | 0.87 ± 0.02 |
Measurements obtained from 1 tail and 2 femoral arteries. Data are expressed as mean ± SEM (n = 5–10/group). For means within the same row, different letters superscripts [a,b] represent significant differences (p < 0.05). An absence of letters indicates no statistical differences. Abbreviations: DBP, diastolic blood pressure; HR, heart rate; HRV, heart rate variability; MAP, mean arterial pressure; MinFV, minimum flow velocity; MFV, mean flow velocity; PFV, peak flow velocity.