Table 7.
Phase 2: Large-artery geometry1.
| SHR | |||
|---|---|---|---|
| Black Beans for 8 Weeks | Washout for 2 Weeks |
Washout for 4 Weeks |
|
| Lumen diameter (µm) | 1670 ± 21 | 1847 ± 107 | 1732 ± 31 |
| Lumen CSA (µm2) | 1990 ± 54 | 2487 ± 286 | 2252 ± 119 |
| Media thickness (µm) | 84.7 ± 2.1 b | 108 ± 8 a | 122 ± 15 a |
| Media CSA (µm) | 444 ± 19 b | 670 ± 84 a | 712 ± 90 a |
| Media:lumen ratio (× 100) | 5.08 ± 0.12 b | 5.9 ± 0.3 b | 7.1 ± 0.9 a |
| External diameter (µm) | 1840 ± 23 | 2187 ± 137 | 2104 ± 54 |
| Adventitia thickness (µm) | 61.0 ± 4.9 | 62 ± 10 | 64 ± 11 |
| Adventitia CSA (µm2) | 384 ± 28 | 396 ± 74 | 353 ± 55 |
1 Measurements obtained from aorta cross-sections. Data are expressed as mean ± SEM (n=4–7/group). For means within the same row, different letters represent significant differences (p<0.05). An absence of letters indicates no statistical differences. Abbreviations: CSA, cross-sectional area; SHR, spontaneously hypertensive rat.