Skip to main content
NCBI home page
Elsevier - PMC COVID-19 Collection logoLink to Elsevier - PMC COVID-19 Collection
. 2012 Jan 8;31(4):265–268. doi: 10.1016/S0254-6272(12)60001-6

Thoughts on Intervention in HIV/AIDS with Traditional Chinese Medicine

Xin-fang WU 1,*, Jie WANG 1, Yong LI 1, Yan-li Tang 1, Dan-dan Zhao 1
PMCID: PMC7147201  PMID: 22462228

Abstract

HIV/AIDS has become a worldwide pandemic and highly active antiretroviral therapy (HAART) is the only generally recognized effective therapy at present. However, various unresolvable problems appear with the widespread use of HAART. Traditional Chinese Medicine shows good efficacy for intervention in HIV/AIDS and could become an effective treatment option.

Keywords: HIV/AIDS, Traditional Chinese Medicine, immunological nonresponders, asymptomatic HIV infection, adverse effects, highly active antiretroviral therapy

References

  • 1.Luo SD, Chen JJ, Wang HY. Natural compounds with anti-HIV activity. Chin Tradit Herb Drug (Supplement) (Chin) 1999;30:40–43. [Google Scholar]
  • 2.Battegay M, Nuesch R, Hirschel B, Kaufmann GR. Immunological recovery and antiretroviral therapy in HIV-1 infection. Lancet Infect Dis. 2006;6:280–287. doi: 10.1016/S1473-3099(06)70463-7. [DOI] [PubMed] [Google Scholar]
  • 3.Pakker NG, Kroon ED, Roos MT, Otto SA, Hall D, Wit FW. Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy. NCAS Study Group. AIDS. 1999;13:203–212. doi: 10.1097/00002030-199902040-00008. [DOI] [PubMed] [Google Scholar]
  • 4.Barrios A, Rendón A, Negredo E, Barreiro P, Garcia-Benayas T, Labarga P. Paradoxical CD4+ T-cell decline in HIV-infected patients with complete virus suppression taking tenofovir and didanosine. AIDS. 2005;19:569–575. doi: 10.1097/01.aids.0000163933.14649.93. [DOI] [PubMed] [Google Scholar]
  • 5.Negredo E, Molto J, Burger D, Viciana P, Ribera E, Puig J. Unexpected CD4 cell count decline in patients receiving didanosine and tenofovir-based regimens despite undetectable viral load. AIDS. 2004;18:459–463. doi: 10.1097/00002030-200402200-00012. [DOI] [PubMed] [Google Scholar]
  • 6.Kelley CF, Kitchen CM, Hunt PW, Benigno R, Hecht FM, Kitahata M. Incomplete peripheral CD4+cell count restoration in HIV-infected patients receiving long-term antiretroviral treatment. Clin Infect Dis. 2009;48:787–794. doi: 10.1086/597093. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Gazzola L, Tincati C, Bellistri GM, Monforte A, Marchetti G. The absence of CD4+ T cell count recovery despite receipt of virologically suppressive highly active antiretroviral therapy: clinical risk, immunological gaps, and therapeutic options. Clin Infect Dis. 2009;48:328–337. doi: 10.1086/595851. [DOI] [PubMed] [Google Scholar]
  • 8.Panel on Antiretroviral Guidelines for Adults and Adolescents . Guidelines for the use of antiretroviral agents in HIV-1 infected adults and adolescents. Department of Health and Human Services; Washington, DC: 2008. [Google Scholar]
  • 9.Yeni PG, Hammer SM, Hirsch MS, Saag MS, Schechteret M, Carpenter CC. Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society–USA Panel. JAMA. 2004;292:251–265. doi: 10.1001/jama.292.2.251. [DOI] [PubMed] [Google Scholar]
  • 10.Moore DM, Hogg RS, Yip B, Wood E, Tyndall M, Braitstein P. Discordant immunologic and virologic responses to highly active antiretroviral therapy are associated with increased mortality and poor adherence to therapy. J Acquir Immune Defic Syndr. 2005;40:288–293. doi: 10.1097/01.qai.0000182847.38098.d1. [DOI] [PubMed] [Google Scholar]
  • 11.Levy Y, Durier C, Krzysiek R, Rabian C, Capitant C, Lascaux AS. Effects of interleukin-2 therapy combined with highly active antiretroviral therapy on immune restoration in HIV-1 infection: a randomized controlled trial. AIDS. 2003;17:343–351. doi: 10.1097/00002030-200302140-00008. [DOI] [PubMed] [Google Scholar]
  • 12.Levy Y, Lacabaratz C, Weiss L, Viard JP, Goujard C, Lelièvre JD, et al. Repeated r-hIL-7 doses improve T cell recovery in HIV-1-infected patients enrolled in a phase i/ii multicentric study [abstract 127]. In: Program and abstracts of the 14th Conference on Retroviruses and Opportunistic Infections (Los Angeles). Alexandria, VA: Foundation for Retrovirology and Human Health; 2007: 112.
  • 13.Chougnet CA, Shearer GM. Regulatory T cells (Treg) and HIV/AIDS: summary of the September 7–8, 2006 workshop. AIDS Res Hum Retroviruses. 2007;23:945–952. doi: 10.1089/aid.2006.0259. [DOI] [PubMed] [Google Scholar]
  • 14.Wang J. The theoretical basis and methods for TCM treatment of AIDS. J Integr Chin West Med (Chin) 1991;11:430–432. [Google Scholar]
  • 15.Panel on clinical practices for the treatment of HIV infection. guidelines for the use of antiretroviral agents in HIV-infected adults and adolescents, 2004. (Accessed January 6, 2005 at http://aidsinfo.nih.gov.).
  • 16.Enger C, Graham N, Peng Y, Chminel JS, Kingsley LA, Detels R. Survival from early, intermediate, and late stages of HIV infection. JAMA. 1996;275:1329–1334. [PubMed] [Google Scholar]
  • 17.Guo HJ, Chen JZ, Guo YM. Clinical observation on early intervention of 32 asymptomatic HIV infected patients with Fuzheng Paidu Granles. Chin Mede Mod Dist Educ Chin (Chin) 2008;6:528–529. [Google Scholar]
  • 18.Henan Province Clinical Experts Group of TCM Treating AIDS The Intervention of 379 asymptomatic HIV infected patients with Yi Ai Kang Capsules. TCM Res (Chin) 2008;21:31–33. [Google Scholar]
  • 19.Montessori V, Press N, Harris M, Akagi L, Montaner JS. Adverse effects of antiretroviral therapy for HIV infection. CMAJ. 2004;170:229–238. [PMC free article] [PubMed] [Google Scholar]
  • 20.Huang L, Zhou CJ, Liang FL, Lu XE, Wang ZM. Treatment of HAART associated hepatic detriments with Dang Gui Shao Yao Powder in 48 AIDS patients. TCM Res (Chin) 2007;20:55–56. [Google Scholar]
  • 21.Liu HY, Jiang SQ, Pei JW. Clinical observation on Jingo Yuan Kang Capsules for treatment of 35 Cases with AIDS Complicated myelosuppression after HAART. J Henan Univ Chin Med (Chin) 2007;22:4–5. [Google Scholar]
  • 22.Zhao JY, Jiang YL. Effects of Jingo Yuan Kang Capsules on bone marrow suppression induced by AZT in mice. Chin Med Herald (Chin) 2007;4:73–74. [Google Scholar]
  • 23.Yu ZM. Preliminary studies on treatment of AIDS related syndromes with TCM. Chin J Med (Chin) 2001;36:46. [Google Scholar]
  • 24.Li GQ, Lu WB, Mpenba N. Inical observation on treatment of 41 cases of AIDS related chronic diarrhea with TCM. Chin J Pract Chin West Med (Chin) 2000;13:1041–1042. [Google Scholar]
  • 25.Zhou W, Sun Y, Wu Z. Acupuncture ameliorates AIDS symptoms in 36 cases. J Tradit Chin Med (Chin) 2000;20:119–121. [PubMed] [Google Scholar]
  • 26.Zhou LH, Lu YP. The advantage of moxibustion in treatment of diarrhea due to AIDS. J Henan Colle Tradit Chin Med (Chin) 2005;20:4–5. [Google Scholar]
  • 27.Tindle HA, Davis RB, Phillips RS, Eisenberg DM. Trends in use of complementary and alternative medicine by US adults: 1997-2002. Altern Ther Health Med. 2005;11:42–49. [PubMed] [Google Scholar]
  • 28.Ma K, Lee SS, Chu EK, Tam DK, Kwong VS, Ho CF. Popular Use of Traditional Chinese Medicine in HIV Patients in the HAART era. AIDS Behav. 2008;12:637–642. doi: 10.1007/s10461-007-9245-4. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Traditional Chinese Medicine are provided here courtesy of Elsevier

RESOURCES