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. 2020 Mar 31;104(4):744–753. doi: 10.1097/TP.0000000000003060

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Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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FIGURE 6. — Histological evaluation of LP treatment effect. A, PAS stain of allografts showed dense interstitial leukocyte infiltrates in the tubulo interstitial space in the NA and prednisolone-treated groups. However, liposomal prednisolone reduced the inflammation markedly. The upper images are taken at a 200-fold magnification (bar: 100 µm), the lower images are the enlarged squares of each group to show the differences in infiltrate density (bar: 50 µm). B, Banff classification of treated allografts reveals decreased interstitial inflammation, tubulitis, and peritubular capillaritis in LP vs NA treatment. Interstitial inflammation is also reduced in LP vs P treatment (mean ± SD. * P < 0.05, 1-way analysis of variance with a Tukey multiple comparisons test. NA = no additional treatment; N = 8, P = prednisolone; N = 9, LP = liposomal prednisolone; N = 9). PAS, periodic acid Schiff.