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. 2013 Sep 13;33(2):156–163. doi: 10.1016/S0254-6272(13)60118-1

Content analysis of systematic reviews on the effectiveness of Traditional Chinese Medicine

Junwen Wang a, Meng Cui a, Hongguan Jiao a, Yuanyuan Tong a, Jun Xu a, Yingkai Zhao a,*, Mei Han b, Jianping Liu b
PMCID: PMC7148763  PMID: 23789210

Abstract

Objective

To evaluate evidence for the efficacy of Traditional Chinese Medicine (TCM) in systematic reviews.

Methods

Chinese (TCMPeriodical Literature Database, Chinese Biological Medicine database, Chinese Medical Current Contents, China Hospital Knowledge Database journal fulltext database, Virtual Machining and Inspection System, and Wanfang) and English (Cochrane Database of Systematic Reviews, PubMed and Embase) databases were searched.

Results

Three thousand, nine hundred and fifty-five articles were initially identified, 606 of which met the inclusion criteria, including 251 in English (83 from the Cochrane Database) and 355 in Chinese. The number of articles published each year increased between 1989 and 2009. Cardiocerebrovascular disease was the most studied target disease. Intervention measures includedTCM preparations (177 articles), acupuncture (133 articles) and combinations of TCM and western medicine (38 articles). Control measures included positive medical (177 articles), basic treatment (100 articles), placebo (219 articles), and blank and mutual (107 articles). All articles included at least one reference; the greatest number was 268. Six of 10 articles with high quality references demonstrated curative effectsagainst target diseasesincludingupper respiratory tract infection, dementia and depression. Interventions that were not recommendedwere tripterygium for rheumatoid arthritis andTCM syndrome differentiation for pediatric nocturia. In 10.4% of the studies, the authors concluded that the intervention had a curative effect. The assessors agreed with the authors' conclusions in 88.32% of cases, but rejected 8.94% (54 articles).

Conclusion

1) Training in systematic review methods, including topic selection, study design, methods and technology, should be improved. 2) Upper respiratory tract infection, dementia and depression may become the predominant diseases treatedby TCM, and the corresponding interventions could be developed into practical applications. 3) Use of non-recommended interventions should be controlled, and there should be more research on side effects.

Key words: Evidence-based medicine, Systematic review, Traditional Chinese Medicine, Curative effect, Content analysis

References

  • 1.Guo R, Canter PH, Ernst E. A systematic review of randomised clinical trials of individualised herbal medicine in any indication. Postgrad Med J. 2007;83(984):633–637. doi: 10.1136/pgmj.2007.060202. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Pittilo RM. Report to ministers from the department of health steering group on the statutory regulation of practitioners of acupuncture, herbal medicine, Traditional Chinese Medicine and other traditional medicine systems practiced in the UK. 2008: (5).
  • 3.Liu JP, Xia Y. Quality appraisal of systematic reviews or meta-analysis on Traditional Chinese Medicine published in Chinese journals. Zhong Guo Zhong Xi Yi Jie He Za-Zhi. 2007;27(4):306–311. [PubMed] [Google Scholar]
  • 4.Derry CJ, Derry S, Mcquay HJ, Moore RA. Systematic review of acupuncture published 1996-2005. Chin Med. 2006;6(4):381–386. doi: 10.7861/clinmedicine.6-4-381. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5.Liu ML, Ma TT, Tang Y. Acupuncture resources in cochrane database of systematic reviews. Zhong Guo Xun Zheng Yi Xue Za Zhi. 2010;10(1):97–99. [Google Scholar]
  • 6.Li TQ, Liu XM, Zhang MM. Assessment of systematic reviews and meta-analyses on Traditional Chinese Medicine published in Chinese journals. Zhong Guo Xun-Zheng Yi Xue Za Zhi. 2007;7(3):180–188. [Google Scholar]
  • 7.Patel M, Gutzwiller F, Paccaud F, Marazzi A. A meta-analysis of acupuncture for chronic pain. Int J Epidemiol. 1989;18(4):900–906. doi: 10.1093/ije/18.4.900. [DOI] [PubMed] [Google Scholar]
  • 8.Cheng ZF, Zhang JH, Hou J. Meta-analysis of Chinese herbs for esophagus precancerous lesion. Shi Yong Zhong Xi Yi Jie He Za Zhi. 1999;12(2):20–21. [Google Scholar]
  • 9.Mao B, Zhang WB, Jiang HL. Chinese medicine for acute upper respiratory tract infection: a systematic review of randomized controlled trials. Zhong Xi Yi Jie He Xue-Bao. 2009;7(8):706–716. doi: 10.3736/jcim20090802. [DOI] [PubMed] [Google Scholar]
  • 10.May BH, Lit M, Xue CC. Herbal medicine for dementia: a systematic review. Phytother Res. 2009;23(4):447–459. doi: 10.1002/ptr.2656. [DOI] [PubMed] [Google Scholar]
  • 11.Wang H, Qi H, Wang BS. Is acupuncture beneficial in depression: a meta-analysis of 8 randomized controlled trials. J Affect Disord. 2008;111(2-3):125–134. doi: 10.1016/j.jad.2008.04.020. [DOI] [PubMed] [Google Scholar]
  • 12.Ee CC, Manheimer E, Pirotta MV, White AR. Acupuncture for pelvic and back pain in pregnancy: a systematic review. Am J Obst Gynecol. 2008;198(3):254–259. doi: 10.1016/j.ajog.2007.11.008. [DOI] [PubMed] [Google Scholar]
  • 13.Trinh KV, Phillips SD, Ho E, Dansma K. Acupuncture for the alleviation of lateral epicondyle pain: a systematic review. Rheumatology. 2004;43(9):1085–1090. doi: 10.1093/rheumatology/keh247. [DOI] [PubMed] [Google Scholar]
  • 14.Coon JT, Ernst E. Andrographispaniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Medica. 2004;70(4):293–298. doi: 10.1055/s-2004-818938. [DOI] [PubMed] [Google Scholar]
  • 15.Canter PH, Lee HS, Ernst E. A systematic review of randomised clinical trials of tripterygiumwilfordii for rheumatoid arthritis. Phytomedicine. 2006;13(5):371–377. doi: 10.1016/j.phymed.2006.01.010. [DOI] [PubMed] [Google Scholar]
  • 16.Guo R, Canter PH, Ernst E. A systematic review of randomised clinical trials of individualised herbal medicine in any indication. Postgrad Med J. 2007;83(984):633–637. doi: 10.1136/pgmj.2007.060202. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Liu JL, Zhang YJ, Song YX, Wang ZN, Xu HM. Chinese and Western Medicine for treatment of functional dyspepsia: a systematic review of randomized controlled trials. Zhong Guo Xun Zheng Yi Xue Za Zhi. 2009;9(12):1315–1322. [Google Scholar]
  • 18.Davis MA, Kononowech RW, Rolin SA, Spierings EL. Acupuncture for tension-type headache: a meta-analysis of randomized, controlled trials. J Pain. 2008;9(8):667–677. doi: 10.1016/j.jpain.2008.03.011. [DOI] [PubMed] [Google Scholar]

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