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1995;5(4):213–226. doi: 10.1007/BF02044138

Disseminated intravascular coagulation: Present and future perspective

R R de Gopegui 1, H B Suliman 2, B F Feldman 2,
PMCID: PMC7149236  PMID: 32834525

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References

  1. Alcaraz A, España F, Sánchez-Cuenca J et al. (1995). Activation of the protein C pathway in acute sepsis. Thromb Res 79:83–93 [DOI] [PubMed] [Google Scholar]
  2. Ampel LL, Marshall S, Caprini JA (1985) Etiology, diagnosis, and treatment of recovery room bleeding/hemorrhage. Heart Lung 14:556–561 [PubMed] [Google Scholar]
  3. Anderson KL, Smith LA, DeGraves FJ et al. (1992) Polymorphonuclear neutrophil leukocyte function in clinical bovine patients and in cows with or withoutStaphylococcus aureus mastitis. Vet Res Commun 16:107–115 [DOI] [PubMed] [Google Scholar]
  4. Angelov A (1989) Intravascular coagulation in relation to pregnancy and delivery. Zentralbl Gynäkol 111:1169–1175 [PubMed] [Google Scholar]
  5. Asakura H, Jokaji H, Saito M et al. (1991) The course of disseminated intravascular coagulation is predicted by changes in thrombin-antithrombin III complex levels—is there any difference between treatment with standard heparin or low-molecular-weight heparin? Blood Coagul Fibrinolysis 2:623–627 [DOI] [PubMed] [Google Scholar]
  6. Asakura H, Jokaji H, Saito M et al. (1994) Study of the balance between coagulation and fibrinolysis in disseminated intravascular coagulation using molecular markers. Blood Coagul and Fibrinolysis 5:829–832 [DOI] [PubMed] [Google Scholar]
  7. Axelsson L, Bergenfeldt M, Bjork P et al. (1990) Release of immunoreactive canine leukocyte elastase normally and in endotoxin and pancreatitis shock. Scand J Clin Lab Invest 50:35–42 [DOI] [PubMed] [Google Scholar]
  8. Badenoch JP, Ramshaw IA, Grant A (1986) Cellular and secreted tumor plasminogen activator: the effect of NaCl. Experientia 42:433–435 [DOI] [PubMed] [Google Scholar]
  9. Baker WF (1989) Clinical aspects of disseminated intravascular coagulation: a clinician's point of view. Semin Thromb Hemost 15:1–43 [DOI] [PubMed] [Google Scholar]
  10. Baker DC, Green RA (1987) Coagulation defects of aflatoxin intoxicated rabbits. Vet Pathol 24:62–70 [DOI] [PubMed] [Google Scholar]
  11. Barnett AH (1991) Pathogenesis of diabetic microangiopathy: an overview. Am J Med 90:675–735 [DOI] [PubMed] [Google Scholar]
  12. Bick RL (1979) Vascular, disorders associated with thrombohemorrhagic phenomena. Semin Thromb Hemost 5:167–183 [DOI] [PubMed] [Google Scholar]
  13. Bick RL (1982) Disseminated intravascular coagulation: clinical/laboratory correlation. Am J Clin Pathol 77:244–253 [Google Scholar]
  14. Bick RL (1985) Disorders of hemostasis and thrombosis. Thieme, New York, pp 157–204 [Google Scholar]
  15. Bick RL (1988) Disseminated intravascular coagulation and related syndromes: a clinical review. Semin Thromb Hemost 14:299–338 [DOI] [PubMed] [Google Scholar]
  16. Bick RL, Baker WF (1992) Diagnostic efficacy of the D-dimer assay in disseminated intravascular coagulation (DIC). Thromb Res 65:785–790 [DOI] [PubMed] [Google Scholar]
  17. Bick RL, Schmalhorst WR, Fekete LF (1976) Disseminated intravascular coagulation and blood component therapy. Transfusion 16:361–376 [DOI] [PubMed] [Google Scholar]
  18. Bigeleisen PE, Kang Y (1991) Thromboelastography as an aid to regional anesthesia: preliminary communication. Reg Anaesth 16:59–61 [PubMed] [Google Scholar]
  19. Blood DC, Radostits OM (1989) Veterinary medicine. Bailliere Tindall, London, pp 984–992 [Google Scholar]
  20. Borrego D, Maria TP, Cascales P et al. (1991) Massive intravascular hemolysis in septicemia caused byClostridium perfringens. Sangre 36:315–317 [PubMed] [Google Scholar]
  21. Bosner H, Pavesic D, Masovcic J et al. (1989) Acute renal failure following necrosis of a myoma in the puerperium. Jugosl Ginekol Perinatol 29:55–58 [PubMed] [Google Scholar]
  22. Boudreaux MK, Weiss RC, Cox N et al. (1989) Evaluation of antithrombin-III activity as a coindicator of disseminated intravascular coagulation in cats with induced feline infectious peritonitis virus infection. Am J Vet Res 50:1910–1913 [PubMed] [Google Scholar]
  23. Bowersock TL, Walker RD, Maddux JM et al. (1990) Hematological changes in calves exposed to a mixture of lipopolysaccharide and crude leukotoxin ofPasteurella haemolytica. Can J Vet Res 54:415–421 [PMC free article] [PubMed] [Google Scholar]
  24. Braun U, Bearth G, Dieth V et al. (1990) A case of disseminated intravascular coagulation (DIC) in a cow with endometritis and fetal death. Schweiz Arch Tierheilkd 132:239–245 [PubMed] [Google Scholar]
  25. Buntain B (1980) Disseminated intravascular coagulopathy (DIC) in a cow with left displaced abomasum, metritis, and mastitis. Agri Pract 1023–1026 [PubMed]
  26. Camiolo SM, Greco WR (1986) Plasminogen activator content of human tumor and adjacent normal tissue measured with fibrin and non-fibrin assays. Cancer Res 46:1788–1794 [PubMed] [Google Scholar]
  27. Carlson GP (1990) Diseases of the hematopoietic and hemolymphatic systems. In: Smith PB (ed) Large animal medicine. CV Mosby, Philadelphia, pp 1068–1082 [Google Scholar]
  28. Carroll RC, Rubinstein E, Worthington RE et al. (1990) Extensive Clq-complement initiated lysis of human platelets by IgG subclass murine monoclonal antibodies to the CD9 antigen. Thromb Res 59:831–839 [DOI] [PubMed] [Google Scholar]
  29. Chuamsumrit kA, Hotrakitya S, Hathirat P et al. (1993) Disseminated intravascular coagulation in children: diagnosis, management and outcome. Southeast Asian J Trop Med Public Health 24 Suppl 1: 229–233 [PubMed] [Google Scholar]
  30. Clauss M, Murray JC, Vianna M et al. (1990) A polypeptide factor produced by fibrosarcoma cells that induces endothelial tissue factor and ehnhances the procoagulant rsponse to tumor necrosis factor/cachectin. J Biol Chem 265:7078–7083 [PubMed] [Google Scholar]
  31. Clemens R, Pramoolsinsap C, Lorenz R et al. (1994) Activation of the coagulation cascade in severe falciparum malaria through the intrinsic pathway. Br J Haematol 87:100–105 [DOI] [PubMed] [Google Scholar]
  32. Clouse LH, Comp PC (1986) The regulation of hemostasis: the protein C system, N Engl J Med 314:1298–1304 [DOI] [PubMed] [Google Scholar]
  33. Concannon KT, Haskins SC, Feldman BF (1992) Hemostatic defects associated with two infusion rates of dextran 70 in dogs. Am J Vet Res 53:1369–1375 [PubMed] [Google Scholar]
  34. Cooley AJ, Clemmons RM, Gross TL (1987) Heartworm disease manifested by encophalomyelitis and myositis in a dog. J AM Vet Med Assoc 190:431–432 [PubMed] [Google Scholar]
  35. Cosgriff TM (1989) Viruses and hemostasis. Rev Infect Dis 11 Suppl 4:S672–688 [DOI] [PubMed] [Google Scholar]
  36. Cotter SM (1992) Hematological emergencies and transfusion medicine. Proc Am Anim Hosp Assoc (59th annual meeting, New Orleans, Louisiana) pp 78–80
  37. Cowell AK, Cowell RL, Tyler RD et al. (1991) Severe systematic reactions to Hymenoptera stings in three dogs. J Am Vet Med Assoc 198:1014–1416 [PubMed] [Google Scholar]
  38. Daugschies A, Altfeld E, Rommel M (1989) Hemostatic alterations in pigs fed sublethal doses ofSarcocystis miescheriana. Vet Parasitol 34:1–13 [DOI] [PubMed] [Google Scholar]
  39. Dillon AR, Braund KG (1982) distal polyneuropathy after canine heartworm disease therapy complicated by disseminated intravascular coagulation. J Am Vet Med Assoc 181:239–242 [PubMed] [Google Scholar]
  40. Dodds WJ (1985) Blood dyscrasias affecting the surgical patient-hemostatic and thrombotic disorders. In: Slatter DH (ed) Textbook of small animal surgery. WB Saunders, Philadelphia, pp 1184–1194 [Google Scholar]
  41. Drazner FH (1982) Clinical implication of disseminated intravascular coagulation. Comp Cont Ed Vet Pract 4:974–891 [Google Scholar]
  42. Duffy MJ (1990) Plasminogen activators and cancer. Blood Coagul Fibrinolysis 1:681–687 [PubMed] [Google Scholar]
  43. Edwards RL, Morgan DL, Rickles FR (1990) Animal tumor procoagulants: registry of the Subcommittee on Haemostasis and Malignancy of the Scientific and Standardization Committee, International Society of Thrombosis and Hameostasis. Thromb Haemost 63:133–138 [PubMed] [Google Scholar]
  44. Ellison GW, King RR, Calderwood MM (1988) Medical and surgical management of multiple organ infarctions secondary to bacterial endocarditis in a dog. J Am Vet Med Assoc 193:1289–1291 [PubMed] [Google Scholar]
  45. Edmond CT (1994) Possible involvement of cytokines in diffuse intravascular coagulation and thrombosis. Baillieres Clin Hameatol 7:453–468 [DOI] [PubMed] [Google Scholar]
  46. Ewert KM, Fessler JF, Templeton CB et al. (1985) Endotoxin-induced hematologic and blood chemical changes in ponies: effect of flunixin meglumine, dexamethasone, and prednisolone. Am J Vet Res 46:24–30 [PubMed] [Google Scholar]
  47. Feldman BF (1981) Disseminated intravascular coagulation. Comp Cont Ed Vet Pract 3:45–52 [Google Scholar]
  48. Feldman BF (1990) Disseminated Intravascular Coagulation (DIC) Disseminated Intravascular Thrombosis (DIT) Consumption Coagulopathy (CC). In: Proceedings of Second International Veterinary Emergency and Critical Care Symposium, San Antonio, Texas
  49. Feldman BF, Madewell BR, O'Neill S (1981) Disseminated intravascular coagulation: antithrombin, plasminogen, and coagulation abnormalities in 41 dogs. J Am Vet Med Assoc 179:151–154 [PubMed] [Google Scholar]
  50. Feldman BF, Thomason KJ, Jain NC (1988) Quantitative platelet disorders. Vet Clin North Am Small Anim Pract 18:35–49 [DOI] [PubMed] [Google Scholar]
  51. Feldman BF, Thomson DB, O'Neill S (1985) Plasma fibronectin concentrations in dogs with disseminated intravascular coagulation. Am J Vet Res 46:1171–1174 [PubMed] [Google Scholar]
  52. Frelier PF, Lewis RM (1984) Hematologic and coagulation abnormalities in acute bovine sarcocystosis. Am J Vet Res 45:40–48 [PubMed] [Google Scholar]
  53. Gentry PA, Feldman BF, Liptrap RM (1991) Haemostasis and parturition re-visited; comparative profiles in mammals. Comp Haematol Int 1:150–154 [Google Scholar]
  54. Gerhards H (1987) Antithrombin III determination in horses. Reference values and acquired antithrombin III deficiency, Tierarztl Prax 15:47–55 [PubMed] [Google Scholar]
  55. Giger U, Gorman NT (1984) Oncologic emergencies in small animals. Part 1. Chemotherapy related and hematologic emergencies. Comp Cont Ed Pract Vet 6:689–698 [Google Scholar]
  56. Goodwin MN (1989) Selected anatomic burn pathology review for clinicians and pathologists. Aviat Space Environ Med 60:B39–43 [PubMed] [Google Scholar]
  57. Gordon SG (1984) Evidence of a tumor proteinase in blood coagulation. In: Honn KV, Sloane BF (eds) Hemostatic mechanisms and metastasis. Martinus Nijhoff, Boston, pp 72–83 [Google Scholar]
  58. Green RA (1981) Hemostasis and disorders of coagulation. Vet Clin North Am Small Anim Pract 11:289–317 [DOI] [PubMed] [Google Scholar]
  59. Green RA (1988) Pathophysiology and antithrombin III deficiency. Vet Clin North Am Small Anim Pract 18:95–104 [DOI] [PubMed] [Google Scholar]
  60. Green RA (1989) Hemostatic disorders: coagulopathies and thrombotic disorders. In: Ettinger SJ (ed) Textbook of veterinary internal medicine. WB Saunders, Philadelphia, pp 2246–2264 [Google Scholar]
  61. Greene CE (1990) Infectious canine hepatitis and canine acidophil cell hepatitis. In: Green CE (ed) Infectious diseases of the dog and cat. WB Saunders, Philadelphia, pp 242–244 [Google Scholar]
  62. Greene CE, Scott FW (1990) Feline panleukopenia. In: Greene CE (ed) Infectious diseases of the dog and cat. WB Saunders, Philadelphia, pp 291–299 [Google Scholar]
  63. Hagiwara MK, Kogika MM, Maluceli BE (1990) Disseminated intravascular coagulation in dogs with aflatoxicosis. J Small Anim Pract 31:239–243 [Google Scholar]
  64. Hall DE (1972) Blood coagulation and its disorders in the dog. Williams & Wilkins, Baltimore, pp 109–128 [Google Scholar]
  65. Hammer AS, Couto CG, Swardson C et al. (1991) Hemostatic abnormalities in dogs with hemangiosarcoma. J Vet Intern Med 5:11–14 [DOI] [PubMed] [Google Scholar]
  66. Hardaway RM (1980a) Mechanism of traumatic shock. Surg Gynecol Obstet 151:65–69 [PubMed] [Google Scholar]
  67. Hardaway RM (1980b) Influence of fibrinogen levels in dogs on mortality from hemorrhagic and traumatic shock. J Trauma 20:417–419 [PubMed] [Google Scholar]
  68. Hardaway RM (1981) Prediction of survival or death of patients in a state of severe shock. Surg Gynecol Obstet 152:200–206 [PubMed] [Google Scholar]
  69. Hardaway RM, Williams CH (1987) Influence of steroids on hemorrhagic and traumatic shock. J Trauma 27:667–670 [DOI] [PubMed] [Google Scholar]
  70. Hardaway RM, Williams CH (1990) A new treatment for traumatic shock and ARDS. Resuscitation 19:61–76 [DOI] [PubMed] [Google Scholar]
  71. Hargis AM, Feldman BF (1991) Evaluation of hemostatic defects secondary to vascular tumors in dogs: 11 cases (1983–1988). J Am Vet Med Assoc 198:891–894 [PubMed] [Google Scholar]
  72. Hauptmann J, Bruggener E (1988) Influence of hiridun on the consumption of antithrombin III in experimental DIC. Folia Haematol Leipz 115:83–87 [PubMed] [Google Scholar]
  73. Helfand SC (1988) Platelets and neoplasia. Vet Clin North Am Small Anim Pract 18:131–135 [DOI] [PubMed] [Google Scholar]
  74. Henry MM, Moore JN, Fischer JK (1991) Influence of an omega-3 fatty acid-enriched ration on in vivo responses of horses to endotoxin. Am J Vet Res 52:523–527 [PubMed] [Google Scholar]
  75. Hersch SL, Kunelis T, Francis RB (1987) The pathogenesis of accelerated fibrinolysis in liver cirrhosis: a critical role for tissue plasminogen activator inhibitors. Blood 69:1315–1319 [PubMed] [Google Scholar]
  76. High KA (1988) Antithrombin III, protein C, and protein S. Naturally occurring anticoagulant proteins. Arch Pathol Lab Med 112:28–36 [PubMed] [Google Scholar]
  77. Holland M, Kelly AB, Synder JR (1986) Antithrombin III activity in horses with large colon torsion. Am J Vet Res 47:897–900 [PubMed] [Google Scholar]
  78. Holman ND, Schneider AJ (1989) Multi-organ damage in exertional heat stroke. Neth J Med 35:38–43 [PubMed] [Google Scholar]
  79. Howerth EW, Greene CE, Prestwood AK (1988) Experimentally induced bluetongue virus infection in white-tailed deer: coagulation, clinical pathologic, and gross pathologic changes. Am J Vet Res 49:1906–1913 [PubMed] [Google Scholar]
  80. Huang HB (1991) Vaccination against and immune response to viral haemorrhagic disease of rabbits: a review of research in the People's Republic of China. Rev Sci Tech 10:481–498 [PubMed] [Google Scholar]
  81. Iashvili BP, Baluda VP, Lukhoyanova TI et al. (1986) The effects of administration of drugs influencing during treatment of patients with burns. Burns Incl Therm Inj 12:184–187 [DOI] [PubMed] [Google Scholar]
  82. Irimura T, McIsaac AM, Carlson DA et al. (1990) Soluble factor in normal tissues that stimulates high-molecular-weight sialoglyco-protein production by human colon carcinoma cells. Cancer Res 50:3331–3338 [PubMed] [Google Scholar]
  83. Isogai E, Isogai H, Onuma M et al. (1989)Escherichia coli associated endotoxemia in dogs with parvovirus infection. Jpn J Vet Sci 51:597–606 [DOI] [PubMed] [Google Scholar]
  84. Jacobse-Geels HEL, Daha MR, Horzinek MC (1980) Isolation and characterization of feline C3 and evidence for the immune complex pathogenesis of feline infectious peritonitis. J Immunol 125:1606–1610 [PubMed] [Google Scholar]
  85. Jandl JH (1991) Blood: pathophysiology. Blackwell Scientific Publications, Boston, pp 510–533 [Google Scholar]
  86. Jensen R, Ens GE (1991) Diagnostic application of thrombotic markers. Clin Hemost Rev 5:1–7 [Google Scholar]
  87. Johnson JT, Zuckerman L, Dunkin PG et al. (1983) Thromboelastography used to monitor a dog with disseminated intravascular coagulation. J Am Anim Hosp Assoc 19:182–186 [Google Scholar]
  88. Johnstone DE (1985) Burns, electrical, chemical and cold injuries. In: Slatter DH (ed) Textbook of small animal surgery. WB Saunders, Philadelphia, p 510–533 [Google Scholar]
  89. Johnstone IB, Crane S (1986) Hemostatic abnormalities in equine colic. Am J Vet Res 47:356–358 [PubMed] [Google Scholar]
  90. Jones DRE, Gruffydd JTJ, McCullagh KG (1980) Disseminated intravascular coagulation in a dog with thoracic neoplasia. J Small Anim Pract 21:303–309 [DOI] [PubMed] [Google Scholar]
  91. Kapina MA, Zelenin MG, Egorov BB (1986) Screening of human and animal tissue cell cultures as potential producers of plasminogen activator. Antibiot Med Biotekhnol 31:756–760 [PubMed] [Google Scholar]
  92. Kaplank AP, Silverberg M (1987) The coagulation-kinin pathway of human plasma. Blood 70:1–15 [PubMed] [Google Scholar]
  93. Katsuura Y, Aoki K, Tanabe H et al. (1994) Characteristic effects of activated human protein C on tissue thromboplastin-induced disseminated intravascular coagulation in rabbits. Thromb Res 76:353–362 [DOI] [PubMed] [Google Scholar]
  94. Kiper ML, Paulsen DP (1988) Acute mastitis and disseminated intravascular coagulopathy caused byPasteurella haemolytica in a cow. J Am Vet Med Assoc 192:205–206 [PubMed] [Google Scholar]
  95. Kobilinsky L, Hardy WD, Day NK (1979) Hypocomplementemia associated with naturally occurring lymphosarcoma in pet cats. J Immunol 122:1239–1242 [PubMed] [Google Scholar]
  96. Kociba GJ, Hathaway JE (1974) Disseminated intravascular coagulation associated with heartworm disease in the dog. J Am Anim Hosp Assoc. 10:373–378 [Google Scholar]
  97. Kokosharov T, Khristov KH, Nikolov N (1990) Disseminated intravascular coagulation in fowls after experimentally induced acute salmonellosis. Vet Sbirka 88:28–31 [Google Scholar]
  98. Krooshof Y, Hellebrekers LJ, Feldman BF (1984) Two cases of combined babesiosis and ehrlichiosis in dogs. Canine Pract 11:12–16 [Google Scholar]
  99. Kubota T, Andoh K, Sadakata H et al. (1991) Tissue factor released from leukemic cells. Thromb Haemost 65:59–63 [PubMed] [Google Scholar]
  100. Lechner K, Kyrle PA (1995) Antithrobin III concentrates—are they clinically useful? Thromb Haemost 73:340–348 [PubMed] [Google Scholar]
  101. Lefrere JJ Conard J, Lerable J et al. (1989) Antithrombin III and hepatocellular carcinoma. Thromb Haemost 62:817 [PubMed] [Google Scholar]
  102. Lipowitz AJ (1985) Surgical complications. In: Slatter DH (ed) Textbook of small animal surgery. WB Saunders, Philadelphia, pp 165–171 [Google Scholar]
  103. Lippincott CL, Schulman AJ (1989) Gastric dilatation volvulus-torsin syndrome. In: Ettinger SJ (ed) Textbook of veterinary internal medicine. WB Saunders, Philadelphia, pp 1278–1288 [Google Scholar]
  104. Lockwood CJ, Bach R, Ghuha A et al. (1991) Amniotic fluid contains tissue factor, a potent initiator of coagulation. Am J Obstet Gynecol 165:1335–1341 [DOI] [PubMed] [Google Scholar]
  105. Madewell BR, Feldman BF (1980) Characterization of anemias associated with neoplasia in small animals. J Am Vet Med Assoc 176:419–425 [PubMed] [Google Scholar]
  106. Mant MJ, King EG (1979) Severe, acute disseminated intravascular coagulation. A reappraisal of its pathophysiology, clinical significance and therapy, based on 47 patients. Am J Med 67:559 [DOI] [PubMed] [Google Scholar]
  107. Masci PP, Rowe EA, Whitaker AN et al. (1990) Fibrinolysis as a feature of disseminated intravascular coagulation (DIC) afterPseudonaja textilis textilis envenomation. Thromb Res 59:859–870 [DOI] [PubMed] [Google Scholar]
  108. McClure JR, McClure JJ (1982) Intravascular coagulopathies associated with alimentary-induced acute laminitis in the pony. In: Proceedings of the first equine endotoxemia-laminitis symposium, (Colden, Colorado, American Association of Equine Practitioners) pp 124–127
  109. McKay DG (1983) Clinical significance of intravascular coagulation. Bibl Haematol 49:63 [DOI] [PubMed] [Google Scholar]
  110. Mohanty D, Ghosh K, Das KC (1991) Studies on the mechanism of synthesis and release of the procoagulant activity from leukaemic cells. Med Oncol Tumor Pharmacother 8:15–21 [DOI] [PubMed] [Google Scholar]
  111. Moher DF (1988) Disorders of blood coagulation. In: Wyngaarden JB, Smith LN (eds), Cecil textbook of medicine. WB Saunders, Philadelphia, pp 1060–1081 [Google Scholar]
  112. Monreal L, Anglés AM, Ruiz de Gopegui R et al. (1993) Valores normales de los parámetros hematológicos y hemostáticos en el conejo. Determinación de nuevos parámetros para modelos experimentales de trombosis y hemostasia. Sangre 38:365–369 [PubMed] [Google Scholar]
  113. Monreal L, Villatoro AJ, Monreal M et al. A comparison of the effects of Low-Molecular Weight and Unfractionated Heparin in horses. Am J Vet Res 56, 10:1281–1289 [PubMed]
  114. Mora A, Cortés C, Roige J et al. (1985) Trasplante hepático ortotópico por hemangioma cavernoso gigante y síndrome de Kasabach-Merritt. Rev Esp Anestesiol Reanim 42:71–74 [PubMed] [Google Scholar]
  115. Morris DD (1988) Recognition and management of disseminated intravascular coagulation in horses. Vet Clin North Am Equine Pract 4:115–143 [DOI] [PubMed] [Google Scholar]
  116. Morris DD (1991) Endotoxemia in horses. A review of cellular and humoral mediators involved in its pathogenesis. J Vet Intern Med 5:167–181 [DOI] [PubMed] [Google Scholar]
  117. Morris DD, Henry MM, Moore JN et al. (1971) Effect of dietary alpha-lineolenic acid on endotoxin-induced production of tumor necrosis factor by peritoneal macrophages in horses. Am J Vet Res 52:528–532 [PubMed] [Google Scholar]
  118. Muller BG (1989) Pathophysiologic and biochemical events in disseminated intravascular coagulation: dysregulation of procoagulant and anticoagulant pathways. Semin Thromb Hemost 15:58–87 [DOI] [PubMed] [Google Scholar]
  119. Murano G, Bick RL (1980) Basic concepts of hemostasis and thrombosis. CRC Press, Boca Raton, pp 43–78 [Google Scholar]
  120. Nakagawa K, Tsuji H, Masuda H et al. (1994) Plasma levels of soluble fibrin in patients with malignancy-associated disseminated intravascular coagulation. Blood Coagul Fibrinolysis 5:725–730 [DOI] [PubMed] [Google Scholar]
  121. Nakamura S, Shimokama T, Yoshikawa Y et al. (1990) Immune complex-induced disseminated intravascular coagulation (DIC). An experimental study. Acta Pathol Jpn 40:476–485 [DOI] [PubMed] [Google Scholar]
  122. Nguyen P, Petitfrere E, Potron G (1995) Mechanisms of the platelet aggregation induced by activated neutrophils and inhibitory effect of specific PAF receptor agonists. Thromb Res 78:33–42 [DOI] [PubMed] [Google Scholar]
  123. Nomura S, Nagata H, Suzuki M et al. (1991) Microparticle generation during in vitro platelet activation by anti-CD9 murine monoclonal antibodies. Thromb Res 62:429–439 [DOI] [PubMed] [Google Scholar]
  124. Nowak G, Markwardt F (1991) Hirudin in disseminated intravascular coagulation. Haemostasis. 21 Suppl 1:142–148 [DOI] [PubMed] [Google Scholar]
  125. Oguma Y, Sakuragawa N, Maki M et al. (1990) Treatment of disseminated intravascular coagulation with low molecular weight heparin. Research Group of FR-860 on DIC in Japan. Semin Thromb Hemost 16:34–40 [PubMed] [Google Scholar]
  126. O'Keefe DA, Couto CG (1988) Coagulation abnormalities associated with neoplasia. Vet Clin North Am Small Anim Pract 18:157–168 [DOI] [PubMed] [Google Scholar]
  127. Olubayo RO, Mugera GM (1985) Pathogenesis of haemorrhages inTrypanosoma vivax infection in cattle. 1. Disseminated intravascular coagulation. Bull Anim Heal Prod Africa 33:211–217 [Google Scholar]
  128. Ono I (1987) Alteration in coagulation and fibrinolysis after burn injury and significance of anticoagulation therapy using heparin and antithrombin III concentrate. Hokkaido Igaku Zasshi 62:108–121 [PubMed] [Google Scholar]
  129. Ordog GJ, Wasserberger J (1986) Coagulation abnormalities in traumatic shock. Crit Care Med 14:519–523 [DOI] [PubMed] [Google Scholar]
  130. O'Rourke L, Feldman BF, Ito RK (1982) coagulation, fibrinolysis, and kinin generation in adult cats. Am J Vet Res 43:1478–1489 [PubMed] [Google Scholar]
  131. Papinger I (1986) Clinical relevance of protein C. Blut 53:63–75 [DOI] [PubMed] [Google Scholar]
  132. Pan IC, Whyard TC, Hess WR et al. (1988) Epitopic diversity of African swine fever virus. Virus Res 9:93–106 [DOI] [PubMed] [Google Scholar]
  133. Parihar MS, Kailashi SC, Pandey AK (1991) A comparison study of phospholipids in human, goat and chick amniotic fluid. Biomed Biochem Acta 50:955–958 [PubMed] [Google Scholar]
  134. Peterson LC, Valentin S, Hedner U (1995) Regulation of extrinsic pathway system in health and disease: the role of factor VIIa and Tissue Factor Pathway Inhibitor. Thromb Res 79:1–35 [DOI] [PubMed] [Google Scholar]
  135. Radomski MW, Jenkins DC, Holmes L et al. (1991) Human colorectal adenocarcinoma cells: differential niric oxide synthesis determines their ability to aggregate platelets. Cancer Res 51:6073–6078 [PubMed] [Google Scholar]
  136. Raphael BG (1982) Disseminated intravascular coagulation during surgery for scoliosis. Clin Orthop 162:41–46 [PubMed] [Google Scholar]
  137. Rebar AH, Hahn FF, Halliwell WH (1980) Microangiopathic hemolytic anemia associated with radiation-induced hemangiosarcomas. Vet Pathol 17:443–454 [DOI] [PubMed] [Google Scholar]
  138. Reilly D, Andreasen PA, Duffy MJ (1991) Urokinase-plasminogen activator in breast cancer: assay by both catalytic and immunoassay. Blood Coagul Fibrinolysis 2:47–50 [PubMed] [Google Scholar]
  139. Roncaglioni MC, Falanga A, D'Alessandro AP et al. (1989) Evidence of a warfarin-sensitive cancer procoagulant in V2 carcinoma. Haematologica 74:143–147 [PubMed] [Google Scholar]
  140. Rosenberg RD (1975) Actions and interactions of antithrombin and heparin. N Engl J Med 292:146–151 [DOI] [PubMed] [Google Scholar]
  141. Ruehl W, Mills C, Feldman BF (1982) Rational therapy in disseminated intravascular coagulation. J Am Vet Med Assoc 181:76–78 [PubMed] [Google Scholar]
  142. Saleh AA, Bottoms GF, Farag AM et al. (1992) Markers for endothelial injury, clotting and platelet activation in preeclampsia. Arch Gynecol Obstet 51:105–110 [DOI] [PubMed] [Google Scholar]
  143. Samama M, Babinet BA (1992) The new heparins. J Mal Vasc 17:91–106 [PubMed] [Google Scholar]
  144. Sandberg H, Bode AP, Dombrose FA et al. (1985) Expression of coagulant activity in human platelets: release of membranous vesicles providing platelet factor 1 and platelet factor 3. Thromb Res 39:63–79 [DOI] [PubMed] [Google Scholar]
  145. Schaeffer RC, Briston C, Chilton SM et al. (1986) Disseminated intravascular coagulation followingEchis carinatus venom in dogs: effects of a synthetic thrombin inhibitor. J Lab Clin Med 107:488–497 [PubMed] [Google Scholar]
  146. Schneider H (1994) Leberpathologie im Rahmen des HELLP-Syndroms. Arch Gynecol Obstet 255 Suppl 2:S245–254 [DOI] [PubMed] [Google Scholar]
  147. Schrier SL (1993) Disorders of hemostasis and coagulation. In: Rubinstein E, Federman DD (eds) Scientific American medicine. New York, Scientific American, vol 5 pp 1–59 [Google Scholar]
  148. Seegers WH (1971) Use and regulation of blood clotting mechanisms. In: Seegers WH (ed) Blood clotting enzymology, Academic Press, New York, p 1 [Google Scholar]
  149. Slappendel RJ (1988a) disseminated intravascular coagulation associated with neoplasia. Vet Clin North Am Small Anim Pract 18:271–273 [PubMed] [Google Scholar]
  150. Slappendel RJ (1988b) Disseminated intravascular coagulation. Vet Clin North Am Small Anim Pract 18:169–184 [DOI] [PubMed] [Google Scholar]
  151. Spearman MA, Ballon BC, Gerrard JM et al. (1991) The inhibition of platelet aggregation of metastatic H-ras-transformed 10T1/2 fibroblasts with castanospermine, an N-linked glycoprotein processing inhibitor. Cancer Lett 60:185–191 [DOI] [PubMed] [Google Scholar]
  152. Stein DS, Libertin CR (1990) Disseminated intravascular coagulation in association with cavitary tuberculosis. South Med J 83:60–63 [DOI] [PubMed] [Google Scholar]
  153. Studdert MJ (1994) Rabbit haemorrhagic disease virus: a calicivirus with differences. Aust Vet J 71:264–264 [DOI] [PubMed] [Google Scholar]
  154. Suchartwatnachai C, Lanasmita V, Chaturachinda K (1991) Obstetric hysterectomy: Ramathibodi's experience 1969–1987. Int J Gynaecol Obstet 36:183–186 [DOI] [PubMed] [Google Scholar]
  155. Suliman HB, Feldman BF (1989) Pathogenesis and aetiology of anaemia in trypanosomiasis with special reference toT. brucei andT. evansi. Vet Bull 59:99–107 [Google Scholar]
  156. Suzuki M, Suematsu M, Miura S et al. (1988) Microcirculatory disturbances in endotoxin-induced disseminated intravascular coagulation. The effects of heparin and gabexate mesilate on locomotive and metabolic changes of neutrophils. Adv Exp Med Biol 242:135–141 [PubMed] [Google Scholar]
  157. Takada A, Takada Y, Mori T et al. (1990) Prevention of severe bleeding by tranexamic acid in a patient with disseminated intravascular coagulation. Thromb Res 58:101–108 [DOI] [PubMed] [Google Scholar]
  158. Tanaka H, Kobayashi N, Maekawa T (1986) Studies on production of antithrombin II with special reference to endotoxin-induced DIC in dogs. Thromb Haemost 56:137–143 [PubMed] [Google Scholar]
  159. Taylor FB Jr (1994) Studies on the inflammatory-coagulant axis in the baboon response toE. coli: regulatory roles of proteins C, S, C4bBP and of inhibitors of tissue factor. Prog Clin Biol Res 388:175–194 [PubMed] [Google Scholar]
  160. Titova SI, Kozlov GI, Mamedgasanov RM (1989) Disorders of blood coagulation and microcirculation in diabetics. Probl Endokrinol Mosk 35:3–7 [PubMed] [Google Scholar]
  161. Toschi V, Fiorini GF, Motta A et al. (1991) Clinical significance of endothelial damage markers in essential mixed cryoglobulinemia. Acta Haematol 86:90–94 [DOI] [PubMed] [Google Scholar]
  162. Uehara S, Honjyo K, Furukawa S et al. (1989) Role of the kallikreinkinin system in human pancreatitis. Adv Exp Med Biol 247B:643–648 [DOI] [PubMed] [Google Scholar]
  163. Ueyama M, Yamamoto I, Sawada Y (1991) Disseminated intravascular coagulation in the early stage after severe burn: the role of excessive thrombin generation. Nippon Geka Gakkai Zasshi 92:907–912 [PubMed] [Google Scholar]
  164. Umeki S, Adachi M, Watanabe M et al. (1988) Gabexate as a therapy for disseminated intravascular coagulation. Arch Intern Med 148:1409–1412 [PubMed] [Google Scholar]
  165. Van Beek EJ, von der Mohlen MA, ten Cate JW et al. (1994) Antithrombin III concentrate in the treatment of DIC: a retrospective follow-up study Neth J Med 45:206–210 [PubMed] [Google Scholar]
  166. Venturini CM, Kaplan JE (1992) Thrombin induces platelet adhesion to endothelial cells. Semin Thromb Hemost 18:275–283 [DOI] [PubMed] [Google Scholar]
  167. Wachtfogel YT, de la Cadena R, Colman R (1993) Structural biology, cellular interactions and pathophisiology of the contact system. Thromb Res 72:1–21 [DOI] [PubMed] [Google Scholar]
  168. Wagner DS, Klein RL, Robinson HB et al. (1990) Placental emboli from a fetus papyraceousm. J Pediatr Surg 25:538–542 [DOI] [PubMed] [Google Scholar]
  169. Walsh LJ, Trincheri G, Waldorf HA et al. (1991) Human dermal mast cells contain and release tumor necrosis factor α, which induces endothelial leukocyte adhesion molecule E. Proc Nat Acad Sci USA 88:4220–4224 [DOI] [PMC free article] [PubMed] [Google Scholar]
  170. Ward MV, Conway DL (1980) A severe case of acute suppurative dermatitis with disseminated intravascular coagulation in a dog. Vet Med Small Anim Clin 75:1564–1568 [PubMed] [Google Scholar]
  171. Warr TA, Rao LV, Rapaport SI (1990) Disseminated intravascular coagulation in rabbits induced by administration of endotoxin or tissue factor: effect of anti-tissue factor antibodies and measurement of plasma extrinsic pathway inhibitor activity. Blood 75:1481–1489 [PubMed] [Google Scholar]
  172. Welch RD, Watkins JP, Taylor TS et al. (1992) Disseminated intravascular coagulation associated with colic in 23 horses (1984–1989). J Vet Intern Med 6:29–35 [DOI] [PubMed] [Google Scholar]
  173. Williams DA (1989) Exocrine pancreatic disease. In Ettinger SJ (ed) Textbook of veterinary internal medicine. WB Saunders, Philadelphia, pp 1520–1554 [Google Scholar]
  174. Wintrobe MW, Lee GR, Boggs DR et al. (1981) Clinical hematology. Lea & Febiger, Philadelphia, pp 104–162 [Google Scholar]
  175. Wisecarver JL, Haire WD (1989) Disseminated intravascular coagulation with multiple arterial thromboses responding to antithrombin-III concentrate infusion. Thromb Res 54:709–717 [DOI] [PubMed] [Google Scholar]
  176. Wu HF, Lundblad RL, Church FC (1995) Neutralization of heparin activity by neutrophil lactoferrin. Blood 85:421–428 [PubMed] [Google Scholar]
  177. Yamazaki M, Asakura H, Aoshima K et al. (1994) Effects of DX-9065a, an orally active, newly synthesized and specific inhibitor of factor Xa, against experimental disseminated intravascular coagulation in rats. Thromb Haemost 72:392–396 [PubMed] [Google Scholar]
  178. Yao SK, Benedict CR, Rosolowsky M et al. (1991) Effect of aspirin on local prostaglandin production and serotonin accumulation in a canine model with coronary cyclic flow variatins or thrombosis. J Mol Cell Cardiol 23:473–482 [DOI] [PubMed] [Google Scholar]
  179. Zoran DL, Jergens AE, Riedesel DH et al. (1992) Evaluation of hemostatic analytes after use of hypertonic saline solution combined with colloids for resuscitation of dogs with hypovolemia. Am J Vet Res 53:1791–1796 [PubMed] [Google Scholar]

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