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. 2019 Oct 4;8:1718. [Version 1] doi: 10.12688/f1000research.20673.1

Table 1. The 10 randomized controlled trials with the highest number of citations.

Number Citations Title Journal Publication
Date
Reference OA Status
1 16741 The Effect of Intensive Treatment of Diabetes on
the Development and Progression of Long-Term
Complications in Insulin-Dependent Diabetes
Mellitus
New England Journal
of Medicine
1993 6 FALSE
2 5177 Tight blood pressure control and risk
of macrovascular and microvascular
complications in type 2†diabetes: UKPDS 38 12
British Medical
Journal
1998 12 TRUE
3 3623 Ranibizumab for Neovascular Age-Related
Macular Degeneration
New England Journal
of Medicine
2006 13 FALSE
4 2343 Ranibizumab versus Verteporfin for
Neovascular Age-Related Macular
Degeneration
New England Journal
of Medicine
2006 14 FALSE
5 2239 The Ocular Hypertension Treatment Study Archives of
Ophthalmology
2002 15 TRUE
6 1736 Pegaptanib for Neovascular Age-Related
Macular Degeneration
New England Journal
of Medicine
2004 16 TRUE
7 1683 The advanced glaucoma intervention study
(AGIS): 7. the relationship between control
of intraocular pressure and visual field
deterioration
American Journal of
Ophthalmology
2000 17 FALSE
8 1641 The Ocular Hypertension Treatment Study Archives of
Ophthalmology
2002 18 TRUE
9 1640 Whole-Body Hypothermia for Neonates with
Hypoxic-Ischemic Encephalopathy
New England Journal
of Medicine
2005 19 FALSE
10 1526 Grading Diabetic Retinopathy from
Stereoscopic Color Fundus Photographs
- An Extension of the Modified Airlie House
Classification
Ophthalmology 1991 20 FALSE

OA, open access.