The content is available as a PDF (828.5 KB).
Conflict of interest: Nothing to report
References
- 1. Döhner H,Stilgenbauer S,Benner A, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 2000; 343: 1919–1916. [DOI] [PubMed] [Google Scholar]
- 2. Schwaenen C,Nessling M,Wessendorf S, et al. Automated array‐based genomic profiling in chronic lymphocytic leukemia: Development of a clinical tool and discovery of recurrent genomic alterations. Proc Natl Acad Sci USA 2004; 101: 1039–1044. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 3. Pfeifer D,Pantic M,Skatulla I, et al. Genome‐wide analysis of DNA copy number changes and LOH in CLL using high‐density SNP arrays. Blood 2007; 109: 1202–1210. [DOI] [PubMed] [Google Scholar]
- 4. Forconi F,Rinaldi A,Kwee I, et al. Genome‐wide DNA analysis identifies recurrent imbalances predicting outcome in chronic lymphocytic leukaemia with 17p deletion. Br J Haematol 2008; 143: 532–536. [DOI] [PubMed] [Google Scholar]
- 5. Chapiro E,Leporrier N,Radford‐Weiss I, et al. Gain of the short arm of chromosome 2 (2p) is a frequent recurring chromosome aberration in untreated chronic lymphocytic leukemia (CLL) at advanced stages. Leuk Res 2010; 34: 63–68. [DOI] [PubMed] [Google Scholar]
- 6. Haferlach C,Dicker F,Schnittger S, et al. Comprehensive genetic characterization of CLL: A study on 506 cases analysed with chromosome banding analysis, interphase FISH, IgV(H) status and immunophenotyping. Leukemia 2007; 21: 2442–2451. [DOI] [PubMed] [Google Scholar]
- 7. Cheson BD,Bennett JM,Grever M, et al. National Cancer Institute‐ Sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment. Blood 1996; 87: 4990–4997. [PubMed] [Google Scholar]
- 8. Matutes E,Owusu‐Ankomah K,Morilla R, et al. The immunological profile of B‐cell disorders and proposal of a scoring system for the diagnosis of CLL. Leukemia 1994; 8: 1640–1645. [PubMed] [Google Scholar]
- 9. Rossi D,Spina V,Cerri M,Rasi S, et al. Stereotyped B‐cell receptor is an independent risk factor of chronic lymphocytic leukemia transformation to Richter syndrome. Clin Cancer Res 2009; 15: 4415–4422. [DOI] [PubMed] [Google Scholar]
- 10. Rossi D,Cerri M,Deambrogi C, et al. The prognostic value of TP53 mutations in chronic lymphocytic leukemia is independent of Del17p13: Implications for overall survival and chemorefractoriness. Clin Cancer Res 2009; 15: 995–1004. [DOI] [PubMed] [Google Scholar]
- 11. Gattei V,Bulian P,Del Principe MI, et al. Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia. Blood 2008; 111: 865–873. [DOI] [PubMed] [Google Scholar]