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. Author manuscript; available in PMC: 2020 Apr 16.
Published in final edited form as: Biochemistry. 2020 Mar 30;59(14):1442–1453. doi: 10.1021/acs.biochem.0c00001

Scheme 1.

Scheme 1

Updated model for kinetics of dNDP formation in the absence of endogenous reductant at 5–10 s−1 (steps A-G), and in the presence of endogenous reductant and multiple turnovers (step H) at 1–2 s−1.