Skip to main content
NCBI home page
Wiley - PMC COVID-19 Collection logoLink to Wiley - PMC COVID-19 Collection
. 2006 Dec 17;540(1):202–209. doi: 10.1111/j.1749-6632.1988.tb27062.x

Autoimmune Reactions Against Myelin Basic Protein Induced by Corona and Measles Virusesa

VOLKER ter MEULEN 1
PMCID: PMC7167907  PMID: 2462802

The content is available as a PDF (483.6 KB).

a

The experiments described in this manuscript were supported by Deutsche Forschungsgemeinschaft.

References

  • 1. Ter Meulen, V. & Stephenson J. R.. 1983. The possible role of viral infections in MS and other related demyelinating diseases In Multiple Sclerosis. Hallpike J. F., Adams C. W. M. & Tourtellotte W. W., Eds.: 241–274. Chapman & Hall, London . [Google Scholar]
  • 2. Nagashima, K. , Wege H., Meyermann R. & Ter Meulen V.. 1978. Corona virus induced subacute demyelinating encephalomyelitis in rats: A morphological analysis. Acta Neuropathol. (Berl) 44: 63–70. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3. Nagashima, K. , Wege H., Meyermann R. & Ter Meulen V.. 1979. Demyelinating encephalomyelitis induced by a long‐term corona virus infection in rats. Acta Neuropathol. (Berl) 45: 205–213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4. Wege, H. , Watanabe R. & Ter Meulen V.. 1984. Relapsing subacute demyelinating encephalomyelitis in rats in the course of coronavirus JHM infection. J. Neuroimmunol. 6: 325–336. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5. Watanabe, R. , Wege H. & Ter Meulen V.. 1987. Comparative analysis of coronavirus JHM induced demyelinating encephalomyelitis in Lewis and Brown‐Norway rats. Lab. Invest. 57: 375–384. [PubMed] [Google Scholar]
  • 6. Liebert, U. G. & Ter Meulen V.. 1987. Virological aspects of measles virus induced encephalomyelitis in Lewis and BN rats. J. Gen. Virol. 68: 1715–1722. [DOI] [PubMed] [Google Scholar]
  • 7. Vandvik, B. , Norrby E., Nordal H. J. & Degré M.. 1976. Oligoclonal measles virusspecific IgG antibodies isolated from cerebrospinal fluids, brain extracts, and sera from patients with subacute sclerosing panencephalitis and multiple sclerosis. Scand. J. Immunol. 5: 979–992. [DOI] [PubMed] [Google Scholar]
  • 8. Vandvik, B. , Norrby E., Steen‐Johnson J. & Stensvold K.. 1978a. Mumps meningitis: Prolonged pleocytosis and occurrence of mumps virus‐specific oligoclonal IgG in the cerebrospinal fluid. Eur. J. Neurol. 17: 13–22. [DOI] [PubMed] [Google Scholar]
  • 9. Vandvik, B. , Weil M. L., Grandien M. & Norrby E.. 1978b. Progressive rubella virus panencephalitis: Synthesis of oligoclonal virus‐specific IgG antibodies and homogeneous free light chains in the central nervous system. Acta Neurol. Scand. 57: 53–64. [DOI] [PubMed] [Google Scholar]
  • 10. Vandvik, B. , Vartdal F., & Norrby E.. 1982. Herpes simplex virus encephalitis: Intrathecal synthesis of oligoclonal virus‐specific IgG, IgA and IgM antibodies. J. Neurol. 228: 25–38. [DOI] [PubMed] [Google Scholar]
  • 11. Vartdal, F. , Vandvik B. & Norrby E.. 1982. Intrathecal synthesis of virus‐specific oligoclonal IgG, IgA and IgM antibodies in a case of varicella‐zoster meningoencephalitis. J. Neurol. Sci. 57: 121–132. [DOI] [PubMed] [Google Scholar]
  • 12. Sköldenberg, B. , Kalimo K., Carlström A., Forsgren M. & Halonen P.. 1981. Herpes simplex encephalitis: A serological follow‐up study. Synthesis of herpes simplex virus immunoglobulin M, A and G antibodies and development of oligoclonal immunoglobulin G in the central nervous system. Acta Neurol. Scand. 63: 273–285. [PubMed] [Google Scholar]
  • 13. Nordal, H. J. , Vandvik B. & Norrby E.. 1978. Demonstration of electrophoretically restricted virus‐specific antibodies in serum and cerebrospinal fluid by imprint electraimmunofixation. Scand. J. Immunol. 7: 381–388. [DOI] [PubMed] [Google Scholar]
  • 14. Dörries, R. & Ter Meulen V.. 1984. Detection and identification of virus‐specific, oligoclonal IgG in unconcentrated cerebrospinal fluid by immunoblot technique. J. Neuroimmunol. 7: 77–89. [DOI] [PubMed] [Google Scholar]
  • 15. Dörries, R. , Watanabe R., Wege H. & Ter Meulen V.. 1987. Intrathecal humoral immune response in corona virus induced encephalomyelitis of Lewis and BN rats In Coronaviruses. Lai M. M. C. & Stohlman S. A., Eds. Adv. Exp. Med. Biol. 218: 373–381. Plenum Press, New York . [PubMed] [Google Scholar]
  • 16. Dörries, R. , Watanabe R., Wege H. & Ter Meulen V.. 1987. Analysis of the intrathecal humoral immune response in Brown Norway (BN) rats, infected with the murine coronavirus JHM. J. Neuroimmunol. 14: 305–316. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17. Dörries, R. , Liebert U. G. & Ter Meulen V.. 1988. Comparative analysis of virus‐specific antibodies and immunoglobulins in serum and cerebrospinal fluid of subacute measles virus induced encephalomyelitis (SAME) in rats and subacute sclerosing panencephalitis (SSPE). J. Neuroimmunol., in press. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18. Watanabe, R. , Wege H. & Ter Meulen V.. 1983. Adoptive transfer of EAE‐like lesions by BMP stimulated lymphocytes from rats with coronavirus‐induced demyelinating encephalomyelitis. Nature 305: 150–153. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 19. Liebert, U. G. , Linington C. & Ter Meulen V.. 1988. Induction of autoimmune reactions to myelin basic protein in measles virus encephalitis in Lewis rats. J. Neuroimmunol. 17: 103–118. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20. Fontana, A. , Fierz W. & Wekerle H.. 1984. Astrocytes present myelin basic protein to encephalitogenic T‐cell lines. Nature 307: 273–276. [DOI] [PubMed] [Google Scholar]
  • 21. Massa, P. T. , Dörries R. & Ter Meulen V.. 1986. Viral particles induce Ia antigen expression on astrocytes. Nature 320: 543–546. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22. Massa, P. T. , Schimpl A., Wecker E. & Ter Meulen V.. 1987. Tumor necrosis factor amplifies measles virus‐mediated Ia induction on astrocytes. Proc. Natl. Acad. Sci. USA 84: 7242–7245. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23. Monroe, J. G. & Cambier J. C.. 1983. B cell activation. III. B cell plasma membrane depolarization and hyper‐Ia antigen expression induced by receptor immunoglobulin cross‐linking are coupled. J. Exp. Med. 158: 1589–1599. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 24. Steeg, P. S. , More R. N., Johnson H. M. & Oppenheim J. J.. 1982a. Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity. J. Exp. Med. 156: 1780–1793. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 25. Steeg, P. S. , Johnson H. M. & Oppenheim J. J.. 1982b. Regulation of murine macrophage Ia expression by an immune interferon‐like lymphokine: Inhibitory effect of endotoxin. J. Immunol. 129: 2402–2406. [PubMed] [Google Scholar]
  • 26. Jahnke, U. , Fischer E. H. & Alvord E. C.. 1985. Sequence homology between certain viral proteins and proteins related to encephalomyelitis and neuritis. Science 229: 282–284. [DOI] [PubMed] [Google Scholar]
  • 27. Fujinami, R. S. & Oldstone M. B. A.. 1985. Amino acid homology between the encephalitogenic site of myelin basic protein and virus: Mechanism for autoimmunity. Science 230: 1043–1045. [DOI] [PubMed] [Google Scholar]
  • 28. Johnson, R. T. , Griffin D. E., Hirsch R. L., Wolinsky J. S., Roedenbeck S., Lindo de Soriano I. & Vaisberg A.. 1984. Measles encephalomyelitis: Clinical and immunologie studies. N. Engl. J. Med. 310: 137–141. [DOI] [PubMed] [Google Scholar]
  • 29. Nepom, J. T. , Weiner H. L., Dichter M. A., Tardieu M., Spriggs D. R., Gramm C. F., Powers M. L., Fields B. N. & Greene M. I.. 1982. Identification of a hemagglutinin‐specific idiotype associated with reovirus recognition shared by lymphoid and neural cells. J. Exp. Med. 155: 155–167. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 30. Londei, M. , Lamb J. R., Bottazzo G. F. & Feldmann M.. 1984. Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells. Nature 312: 639–641. [DOI] [PubMed] [Google Scholar]
  • 31. Massa, P. T. , Ter Meulen V. & Fontana A.. 1987. Hyperinducibility of Ia antigen on astrocytes correlates with strain‐specific susceptibility to experimental autoimmune encephalomyelitis. Proc. Natl. Acad. Sci. USA 84: 4219–4223. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of the New York Academy of Sciences are provided here courtesy of Wiley

RESOURCES