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. 2006 Dec 16;420(1):391–400. doi: 10.1111/j.1749-6632.1983.tb22228.x

Negative Staining and Immune Electron Microscopy as Techniques for Rapid Diagnosis of Viral Agents

M RIEPENHOFF‐TALTY 1, H J BARRETT 1, B A SPADA 1, P L OGRA 1
PMCID: PMC7168088  PMID: 6326645

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References

  • 1. ADLER, J. L. & ZICKL R., 1969. Winter vomiting disease. J. Infect. Dis. 119: 668–673. [DOI] [PubMed] [Google Scholar]
  • 2. ASHLEY, C. R. , CAUL E. O. & PAVER W. K.. 1979. Astrovirus‐associated gastroenteritis in children. J. Clin. Path. 31: 939–941. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3. BISHOP, R. F. , DAVIDSON G. P., HOLMES I. H. & RUCK B. J.. 1973. Virus particles in epithelial cells of duodenal mucosa from children with acute nonbacterial gastroenteritis. Lancet 2: 1281–1283. [DOI] [PubMed] [Google Scholar]
  • 4. BRANDT, C. D. , KIM H. W., RODRIQUEZ W. J., THOMAS L., YOLKEN R. H., ARROBIO J. O., KAPIKIAN A. Z., PARROTT R. H. & CHANOCK R. M.. 1981. Comparison of direct electron microscopy, immune electron microscopy, and rotavirus enzyme‐linked immunosorbent assay for detection of gastroenteritis. J. Clin. Micro. 13: 976–981. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5. CHIBA, W. , SAKUMA Y., KOGASAKA R., AKIHARA M., TERASHIMA H., HORINO K. & NAKAO T.. 1980. Fecal shedding of virus in relation to the days of illness in gastroenteritis due to calicivirus. 142: 247–249. [DOI] [PubMed] [Google Scholar]
  • 6. FLEWETT, T. H. 1978. Electron microscopy in the diagnosis of infectious diarrhea 173: 538–543. [PubMed] [Google Scholar]
  • 7. FLEWETT, T. H. , DAVIES H., BRYDEN A. S. & ROBERTSON M. J.. 1974. Acute gastroenteritis associated with reovirus‐like particles. J. Clin. Path. 27: 608–614. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8. KAPIKIAN, A. Z. , WYATT R. G., DOLIN R., THORNHILL T. S., KALICA A. R. & CHANOCK R. M.. 1972. Visualization by immune electron microscopy of a 27‐nm particle associated with acute infectious nonbacterial gastroenteritis. J. Virol. 10: 1075–1081. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9. KOGASAKA, R. , NAKAMURA S., CHIBA S., SAKUMA Y., TERASHIMA H., YOKOYAMA T. & NAKAO T.. 1981. The 33 to 39 nm virus‐like particles tentatively designated as Sapporo agent associated with an outbreak of acute gastroenteritis. J. Med. Virol. 8: 187–193. [DOI] [PubMed] [Google Scholar]
  • 10. KOGASAKA, R. , SAKUMA Y., CHIBA S., AKIHARA M., NORINO K. & NAKAO T.. 1980. Small round virus‐like particles associated with acute gastroenteritis in Japanese children. J. Med. Virol. 5: 151–160. [DOI] [PubMed] [Google Scholar]
  • 11. KURTZ, J. B. , LEE T. W., PICKERING D.. 1977. Astrovirus associated gastroenteritis in a children's ward. J. Clin. Path. 30: 948–952. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 12. MADELEY, C. R. & COSCROVE B. P.. 1976. Caliciviruses in man. Lancet 1: 199–200. [DOI] [PubMed] [Google Scholar]
  • 13. MADELEY, C. R. & COSGROVE B. P.. 1975. Viruses in infantile gastroenteritis. Lancet 2: 124. [DOI] [PubMed] [Google Scholar]
  • 14. MCSWIGGAN, D. A. , CUBITT D. & MOORE W.. 1978. Calicivirus associated with winter vomiting disease. Lancet 1: 215. [DOI] [PubMed] [Google Scholar]
  • 15. MIDDLETON, P. J. , SZYMANSKI M. T., ABBOTT G. D., BORTOLUSSI R. & HAMILTON J. R.. 1974. Orbivirus acute gastroenteritis of infancy. Lancet 1: 1241–1244. [Google Scholar]
  • 16. MIDDLETON, P. J. , SZYMANSKI M. T. & PETRIC M.. 1977. Viruses associated with acute gastroenteritis in young children. Am. J. Dis. Child. 131: 733–737. [DOI] [PubMed] [Google Scholar]
  • 17. SPRATT, H. C. , MARKS M. I., GOMERSALL M., GILL P. & PAL C. H.. 1978. Nosocomial infantile gastroenteritis associated with minirotavirus and calicivirus. J. Peds. 93: 922–926. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18. SUZUKI, H. , KONNO T., KATSUZAWA T., IMAI A., TAZAWA F., ISHIDA N., KATSUSHIMA N. & SALAMOTO M.. 1979. The occurrence of calicivirus in infants with acute gastroenteritis. J. Med. Virol. 4: 321–326. [DOI] [PubMed] [Google Scholar]
  • 19. TANIGUCHI, K. , URASAWA S. & URASAWA T.. 1979. Virus‐like particle, 35 to 40 nm associated with an institutional outbreak of acute gastroenteritis in adults. J. Clin. Micro. 10: 730–736. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20. THORNHILL, T. S. , WYATT R. G., KALICA A. R., DOLIN R., CHANOCK R. M. & KAPIKIAN A. Z.. 1977. Detection by immune electron microscopy of 26–27 nm virus‐like particles associated with two family outbreaks of gastroenteritis. J. Infect. Dis. 135: 20–27. [DOI] [PubMed] [Google Scholar]

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