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. 2004 May 12;183(2):810–814. doi: 10.1016/0042-6822(91)91016-A

Sequence analysis of the 3′-end of feline calicivirus genome☆

Yukinobu Tohya a, Yasuko Taniguchi a, Eiji Takahashi a, Etsuko Utagawa ∗, Naokazu Takeda ∗, Kikuko Miyamura ∗, Shudo Yamazaki ∗, Takeshi Mikami 1
PMCID: PMC7172241  PMID: 1853578

Abstract

The nucleotide sequence of the 3′-end of the Japanese F4 strain of feline calicivirus (FCV) RNA was determined from a cloned cDNA of 3.5 kbp. We found three open reading frames (ORFs). The largest ORF encoded a 668-amino acid protein of 73,588 Da, which was presumably the capsid precursor protein of FCV and had significant amino acid sequence homology with the VP3 of picornaviruses. A small ORF at the extreme 3′-end was compared with that of the F9 strain of FCV, a vaccine strain originally from the U.S. Highly conserved amino acid sequences were shown, suggesting that this ORF might be functional and encode a putative 106-amino acid protein of 12,153 Da. The other ORF in the 5′-flanking region of the cDNA had consensus amino acid sequences conserved among the RNA-dependent RNA polymerases.

Footnotes

☆

Sequence data from this article have been deposited with the DDBJ and EMBL/GenBank Data Libraries under Accession No. D90357.

References

  • 1.Schaffer F.L., Bachrach H.L., Brown F., Gillespie J.H., Burroughs J.N., Madin S.H., Madeley C.R., Povey R.C., Scott F., Smith A.W., Studdert M.J. Intervirology. 1980;14:1–6. doi: 10.1159/000149155. [DOI] [PubMed] [Google Scholar]
  • 2.Cooper P.D., Agol V.I., Bachrach H.L., Brown F., Ghendon Y., Gibbs A.J., Gillespie J.H., Lonberg-Holm K., Mandel B., Melnick J.L., Mohanty S.B., Povey R.C., Rueckert R.R., Schaffer F.L., Tyrrell D.A.J. Intervirology. 1978;10:165–180. [Google Scholar]
  • 3.Almeida J.D., Waterson A.P., Prydie J., Fletcher E.W.L. Arch. Gesamte Virusforsch. 1968;25:105–114. doi: 10.1007/BF01243095. [DOI] [PubMed] [Google Scholar]
  • 4.Peterson J.E., Studdert M.J. Arch. Gesamte Virusforsch. 1970;32:249–260. [PubMed] [Google Scholar]
  • 5.Bachrach H.L., Hess W.R. Biochem. Biophys. Res. Commun. 1973;55:141–149. doi: 10.1016/s0006-291x(73)80070-1. [DOI] [PubMed] [Google Scholar]
  • 6.Burroughs J.N., Brown F. J. Gen. Virol. 1974;22:281–286. doi: 10.1099/0022-1317-22-2-281. [DOI] [PubMed] [Google Scholar]
  • 7.Schaffer F.L., Soergel M.E. J. Virol. 1976;19:925–931. doi: 10.1128/jvi.19.3.925-931.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Ehresmann D.W., Schaffer F.L. J. Virol. 1977;22:572–576. doi: 10.1128/jvi.22.2.572-576.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Black D.N., Burroughs J.N., Harris T.J.R., Brown F. Nature (London) 1978;274:614–615. doi: 10.1038/274614a0. [DOI] [PubMed] [Google Scholar]
  • 10.Neill J.D., Mengeling W.L. Virus Res. 1988;11:59–72. doi: 10.1016/0168-1702(88)90067-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Crandell R.A., Madin S.H. Am. J. Vet. Res. 1960;21:551–556. [Google Scholar]
  • 12.Carter M.J. Arch. Virol. 1990;114:143–152. doi: 10.1007/BF01310744. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Bittle J.L., York C.J., Newberne J.W., Martin M. Am. J. Vet. Res. 1960;21:547–550. [Google Scholar]
  • 14.Neill J.D. Virus Res. 1990;17:145–160. doi: 10.1016/0168-1702(90)90061-f. [DOI] [PubMed] [Google Scholar]
  • 15.Tohya Y., Taniguchi Y., Tsubakimoto M., Takahashi E., Mikami T. Jpn. J. Vet. Sci. 1990;52:251–256. doi: 10.1292/jvms1939.52.251. [DOI] [PubMed] [Google Scholar]
  • 16.Tohya Y., Masuoka K., Takahashi E., Mikami T. Arch. Virol. 1991 doi: 10.1007/BF01310763. in press. [DOI] [PubMed] [Google Scholar]
  • 17.Takahashi E., Konishi S., Ogata M. Jpn. J. Vet. Sci. 1971;33:81–87. doi: 10.1292/jvms1939.33.81. [DOI] [PubMed] [Google Scholar]
  • 18.Gubler U., Hoffman B.J. Gene. 1983;25:263–269. doi: 10.1016/0378-1119(83)90230-5. [DOI] [PubMed] [Google Scholar]
  • 19.Chomczynski P., Sacchi N. Anal. Biochem. 1987;162:156–159. doi: 10.1006/abio.1987.9999. [DOI] [PubMed] [Google Scholar]
  • 20.Sambrook J., Fritsch E.F., Maniatis T. 2nd ed. Cold Spring Harbor Laboratory; Cold Spring Harbor, NY: 1989. (Molecular Cloning: A Laboratory Manual). [Google Scholar]
  • 21.Sanger F., Nicklen S., Coulson A.R. Vol. 74. 1977. pp. 5463–5467. (Proc. Natl. Acad. Sci. USA). [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22.Argos P., Kamer G., Nicklin M.J.H., Wimmer E. Nucleic Acids Res. 1984;12:7251–7267. doi: 10.1093/nar/12.18.7251. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23.Fretz M., Schaffer F.L. Virology. 1978;89:318–321. doi: 10.1016/0042-6822(78)90065-x. [DOI] [PubMed] [Google Scholar]
  • 24.Carter M.J. Arch. Virol. 1989;108:69–79. doi: 10.1007/BF01313744. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 25.Burroughs J.N., Doel T.R., Smale C.J., Brown F. J. Gen. Virol. 1978;40:161–174. doi: 10.1099/0022-1317-40-1-161. [DOI] [PubMed] [Google Scholar]
  • 26.Palmenberg A.C. In: Molecular Aspects of picornavirus Infection and Detection. Semler B.L., Ehrenfeld E., editors. 1989. pp. 211–241. (Am. Soc. Microbiol.). Washington, DC. [Google Scholar]
  • 27.Strauss J.H., Strauss E.G. Annu. Rev. Microbiol. 1988;42:657–683. doi: 10.1146/annurev.mi.42.100188.003301. [DOI] [PubMed] [Google Scholar]
  • 28.Schaffer F.L. In: Fraenkel-Conrat H., Wagner R.R., editors. Vol. 14. Plenum; New York: 1979. pp. 249–284. (Comprehensive Virology). [Google Scholar]
  • 29.Spaan W., Cavanagh D., Horzinek M.C. J. Gen. Virol. 1988;69:2939–2952. doi: 10.1099/0022-1317-69-12-2939. [DOI] [PubMed] [Google Scholar]

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