Fig. 3.

Epitope antibody titers from the first animal trial. Ab titers from mouse sera after completion of the first animal trial as measured by ELISA corresponding to plates coated with EFPs are shown. Ab titers specific to (A) EFP-YSNIGVCK, (B) EFP-SQSGQVKI, (C), EFP-GPRLQPY and (D) EFP-WAFYVR were measured. Each treatment group’s mean titer is compared to the ΔHBcAg negative control by ANOVA analysis. Standard error bars are shown for each treatment group (^* = P ≤ 0.05, ^** = P ≤ 0.01, ^*** = P ≤ 0.001).