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. 2004 Apr 11;2:187–194. doi: 10.1016/0896-8411(89)90130-3

Virus-induced autoimmunity: Molecular mimicry as a route to autoimmune disease

Michael BA Oldstone 1
PMCID: PMC7172880  PMID: 2673272

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References

  • 1.Oldstone M.B.A. Membranes and Viruses in Immunopathology. Academic Press; New York: 1972. Virus-induced autoimmune disease: Viruses in the production and prevention of autoimmune disease; pp. 469–475. [Google Scholar]
  • 2.Tonietti G., Oldstone M.B.A., Dixon F.J. The effect of induced chronic viral infections on the immunologic diseases of New Zealand mice. J. Exp. Med. 1970;132:89–109. doi: 10.1084/jem.132.1.89. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Lampert P.W., Oldstone M.B.A. Host IgG and C3 deposits in the choroid plexus during spontaneous immune complex disease. Science. 1973;180:408–410. doi: 10.1126/science.180.4084.408. [DOI] [PubMed] [Google Scholar]
  • 4.Oldstone M.B.A. Molecular mimicry and autoimmune disease. Cell. 1987;50:819–820. doi: 10.1016/0092-8674(87)90507-1. [DOI] [PubMed] [Google Scholar]
  • 5.McChesney M.B., Oldstone M.B.A. Viruses perturb lymphocyte functions: Selected principles characterizing virus-induced immunosuppression. Ann. Rev. Immunol. 1987;5:279–304. doi: 10.1146/annurev.iy.05.040187.001431. [DOI] [PubMed] [Google Scholar]
  • 6.McChesney M.B., Oldstone M.B.A. Virus-induced immunosuppression: Infections with measles virus and human immunodeficiency virus. Adv. Immunol. 1989 doi: 10.1016/s0065-2776(08)60696-3. (In press) [DOI] [PubMed] [Google Scholar]
  • 7.Dales S., Fujinami R.S., Oldstone M.B.A. Serologic relatedness between Thyl.2 and actin revealed by monoclonal antibody. J. Immunol. 1983;131:1332–1338. [PubMed] [Google Scholar]
  • 8.Lane D.P., Hoeffler W.K. SV40 large T shares an antigenic determinant with cellular protein of molecular weight 68,000. Nature. 1980;288:167–170. doi: 10.1038/288167a0. [DOI] [PubMed] [Google Scholar]
  • 9.Fujinami R.S., Oldstone M.B.A., Wroblewska Z., Frankel M.E., Koprowski H. Vol. 80. 1983. Molecular mimicry in virus infection: Cross-reaction of measles phosphoprotein or of herpes simplex virus protein with human intermediate filaments; pp. 2346–2350. (Proc. Natl. Acad. Sci. USA). [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Srinivasappa J., Saegusa J., Prabhakar B.S., Gentry M.K., Buchmeier M.J., Wiktor T.J., Koprowski H., Oldstone M.B.A., Notkins A.L. Molecular mimicry: Frequency of reactivity of monoclonal antiviral anitbodies with normal tissues. J. Virol. 1986;57:397–401. doi: 10.1128/jvi.57.1.397-401.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Fujinami R.S., Oldstone M.B.A. Amino acid homology and immune responses between the encephalitogenic site of myelin basic protein and virus: A mechanism for autoimmunity. Science. 1985;230:1043–1045. doi: 10.1126/science.2414848. [DOI] [PubMed] [Google Scholar]
  • 12.Schwimmbeck P.L., Yu D.T.Y., Oldstone M.B.A. Autoantibodies to HLA-B27 in the sera of HLA-B27 patients with ankylosing spondylitis and Reiter's syndrome: Molecular mimicry with Klebsiella pneumoniae as potential mechanism of atuoimmune disease. J. Exp. Med. 1987;166:173–181. doi: 10.1084/jem.166.1.173. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Husby G., Tsuchiya N., Schwimmbeck P.L., Keat A., Pahle J.A., Oldstone M.B.A., Williams R.C., Jr. HLA-B27 related antigens in articular tissues of patients with ankylosing spondylitis. Arthritis Rheum. 1988 (Submitted) [Google Scholar]
  • 14.Schwimmbeck P.L., Oldstone M.B.A. Autoimmune pathogenesis for ankylosing spondylitis (AS) and Reiter's syndrome (RS): Autoantibodies against an epitope shared by HLA-B27 and Klebsiella pneumoniae nitrogenase in sera of HLA-B27 patients with AS and RS. AAP Transactions. 1987;C:28–39. [PubMed] [Google Scholar]
  • 15.Dyrberg T., Oldstone M.B.A. Peptides as probes to study molecular mimicry and virus induced autoimmunity. Curr. Top. Microbiol. Immunol. 1986:25–39. doi: 10.1007/978-3-642-71440-5_3. [DOI] [PubMed] [Google Scholar]
  • 16.Schwimmbeck P.L., Dyrberg T., Drachman D., Oldstone M.B.A. Molecular mimicry and myasthenia gravis: Uncovering a novel site of the acetylcholine receptor that has biologic activity and reacts immunochemically with herpes simplex virus. J. Clin. Invest. 1988 doi: 10.1172/JCI114282. (Submitted) [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Chen Arthritis Rheum. 1987;31:38–42. [Google Scholar]

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