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. 2003 Sep 27;311(8075):1176–1178. doi: 10.1016/S0140-6736(78)90967-4

ASYMPTOMATIC ENDEMIC ROTAVIRUS INFECTIONS IN THE NEWBORN

IL Chrystie 1, BM Totterdell 1, JE Banatvala 1
PMCID: PMC7173156  PMID: 77944

Abstract

Between May 1, 1976, and May 14, 1977, 343 (32·5%) of 1056 5-day-old babies in newborn nurseries excreted rotaviruses. The infection-rate was highest during winter (49%). 76% of infected babies at this time were bottle-fed. 41% of neonates excreted low amounts of virus (108 particles/g fæces); older children tended to excrete >1010 particles/g fæces. Infected breast-fed babies excreted less virus than those who were bottle-fed. Stools of breast-fed babies often contained clumps of complete "smooth" rotavirus particles. When the newborn nurseries were transferred to a newly built hospital wing, infection appeared in the new wards, including those admitting only new patients, within a short period. Infection was either mild (8%) or symptomless (92%), and even babies with symptoms required no treatment.

References

REFERENCES

  • 1.Davidson G.P., Bishop R.F., Townley R.R.W., Holmes I.H., Ruck B.J. Lancet. 1975;i:242. doi: 10.1016/s0140-6736(75)91140-x. [DOI] [PubMed] [Google Scholar]
  • 2.Lancet. 1975;i:257. [Google Scholar]
  • 3.Mebus C.A., Underdahl N.R., Rhodes M.B., Twiehaus M.J. Univ. Nebraska Agric. exp. Station Res. Bull. 1969;(no. 233) [Google Scholar]
  • 4.Woode G.N., Bridger J.C. Vet. Rec. 1975;96:85. doi: 10.1136/vr.96.4.85. [DOI] [PubMed] [Google Scholar]
  • 5.Commun. Dis. Rep. publ. Hlth Lab. Serv. 1977;(no. 30) [Google Scholar]
  • 6.Chrystie I.L., Totterdell B., Baber M.J., Scopes J.W., Banatvala J.E. Lancet. 1975;ii:79. doi: 10.1016/s0140-6736(75)90525-5. [DOI] [PubMed] [Google Scholar]
  • 7.Totterdell B.M., Chrystie I.L., Banatvala J.E. Archs Dis. Childh. 1976;51:924. doi: 10.1136/adc.51.12.924. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 8.Bishop R.F., Hewstone A.S., Davidson G.P., Townley R.R.W., Holmes I.H., Ruck B.J. J. clin. Path. 1976;29:46. doi: 10.1136/jcp.29.1.46. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Cameron D.J.S., Bishop R.F., Davidson G.P., Townley R.R.W., Holmes I.H., Ruck B.J. Med. J. Aust. 1976;i:85. [PubMed] [Google Scholar]
  • 10.Murphy A.M., Albrey M.B., Crewe E.B. Lancet. 1977;ii:1149. doi: 10.1016/S0140-6736(77)91538-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Mebus C.A., Stair E.L., Underdahl N.R., Twiehaus M.J. Vet. Pathol. 1971;8:490. doi: 10.1177/030098587301000208. [DOI] [PubMed] [Google Scholar]
  • 12.Pierce N.F. In: Elliot K., Knight J., editors. 1976. p. 129. (Acute Diarrhoea in Childhood). Ciba Foundation Symposium no. 42 Amsterdam. [Google Scholar]
  • 13.Edmonson W.P., Rothenburg R., White P.W., Gwaltney J.M., Jr. Am. J. Epidem. 1971;93:480. doi: 10.1093/oxfordjournals.aje.a121282. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 14.Starr J.G., Bart R.D., Jr., Gold E. New Engl. J. Med. 1970;282:1075. doi: 10.1056/NEJM197005072821905. [DOI] [PubMed] [Google Scholar]
  • 15.Schweitzer I.L., Spears R.L. New Engl. J. Med. 1970;283:570. doi: 10.1056/NEJM197009102831105. [DOI] [PubMed] [Google Scholar]
  • 16.Holmes I.H., Ruck B.J., Bishop R.F., Davidson G.P. J. Virol. 1975;16:937. [Google Scholar]
  • 17.Theil K.W., Bohl E.H., Agnes A.G. Am. J. vet. Res. 1977;38:1765. [PubMed] [Google Scholar]
  • 18.Babiuk L.A., Mohammed K., Spence L., Fauvel M., Petro R. J. clin. Microbiol. 1977;6:610. doi: 10.1128/jcm.6.6.610-617.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 19.Almeida, J. D., Hall, T., Banatvala, J. E., Totterdell, B. M., Chrystie, I. L. (In the press).
  • 20.Woode G.N. In: Elliot K., Knight J., editors. 1976. p. 251. (Acute Diarrhoea in Childhood). Ciba Foundation Symposium no. 42 Amsterdam. [Google Scholar]
  • 21.Mathan, M. Unpublished.
  • 22.Simhon A., Mata L. Lancet. 1978;i:39. doi: 10.1016/s0140-6736(78)90382-3. [DOI] [PubMed] [Google Scholar]
  • 23.Inglis G.C., Sommerville R.G., McClelland D.B.L. Lancet. 1978;i:559. doi: 10.1016/s0140-6736(78)90589-5. [DOI] [PubMed] [Google Scholar]
  • 24.Thouless M.E., Bryden A.S., Flewett T.H. Br. med. J. 1977;ii:1390. doi: 10.1136/bmj.2.6099.1390. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 25.Matthews T.H.J., Nair C.D.G., Lawrence M.K., Tyrrell D.A.J. Lancet. 1976;ii:1387. doi: 10.1016/s0140-6736(76)91922-x. [DOI] [PubMed] [Google Scholar]
  • 26.Yolken, R. H. Unpublished.
  • 27.Middleton P.J., Szymanski M.T., Petric M. Am. J. Dis. Child. 1977;131:733. doi: 10.1001/archpedi.1977.02120200015004. [DOI] [PubMed] [Google Scholar]

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