Correction to: Scientific Reports 10.1038/s41598-020-58410-y, published online 06 February 2020
This Article contains errors in Table 3. In this Article, data values provided for Participant 16 are incorrect. The correct Table 3 appears below as Table 1.
Table 1.
Participant | PR/RT | int | env | Viral Load (copies/mL) | ARV Exposure | ARV Regimen Type | |||
---|---|---|---|---|---|---|---|---|---|
Number of Haplotypes | Haplotype Diversity | Number of Haplotypes | Haplotype Diversity | Number of Haplotypes | Haplotype Diversity | ||||
8 | NA | NA | 1 | 0 | NA | NA | E | 2 NRTI+1 ENH+1 INSTI | |
9 | NA | NA | 5 | 0.066 | 11 | 0.038 | 476 | E | |
12 | 1 | 0 | 4 | 0.727 | 2 | 0.393 | 77 | E | 2 NRTI+1 NNRTI |
13 | NA | NA | 1 | 0 | 2 | 0.302 | N | ||
16 | 3 | 0.33 | 1 | 0 | 3 | 0.415 | E | ||
18 | NA | NA | 1 | 0 | NA | NA | 119149 | E | |
19 | 2 | 0.436 | 2 | 0.499 | 4 | 0.721 | 244 | N | |
20 | 2 | 0.479 | 1 | 0 | 2 | 0.281 | 5663 | E | 1 NRTI+1 PI+1 ENH |
23 | 3 | 0.352 | 2 | 0.484 | NA | NA | 927 | E | 2 NRTI+1 ENH+1 INSTI |
25 | 1 | 0 | 1 | 0 | NA | NA | E | 2 NRTI+1 ENH+1 INSTI | |
26 | 2 | 0.452 | 2 | 0.466 | NA | NA | N | ||
27 | 1 | 0 | 1 | 0 | NA | NA | 11 | E | 1 PI+1 ENH |
29 | 2 | 0.464 | 2 | 0.25 | 5 | 0.62 | 1 | E | 2 NRTI+1 ENH+1 INSTI |
30 | 2 | 0.441 | 3 | 0.579 | 1 | 0 | 625 | E | |
31 | 3 | 0.64 | 3 | 0.526 | 2 | 0.312 | E | 2 NRTI+1 INSTI | |
32 | 2 | 0.146 | 2 | 0.339 | 2 | 0.498 | E | 2 NRTI+1 NNRTI+1 PI+1 ENH | |
33 | 1 | 0 | 3 | 0.563 | 3 | 0.601 | E | 2 NRTI+1 ENH+1 INSTI | |
34 | 2 | 0.429 | 2 | 0.2 | 1 | 0 | E | 2 NRTI+1 INSTI | |
35 | 2 | 0.385 | 1 | 0 | 3 | 0.446 | E | 2 NRTI+1 INSTI | |
37 | 2 | 0.274 | 1 | 0 | 10 | 0.027 | 81 | E | |
39 | NA | NA | 1 | 0 | NA | NA | E | 2 NRTI+1 ENH+1 INSTI | |
40 | 2 | 0.494 | 4 | 0.692 | 3 | 0.623 | E | ||
42 | 1 | 0 | 2 | 0.215 | 2 | 0.445 | 13979 | E | 2 NRTI+1 ENH+1 INSTI |
43 | 1 | 0 | 7 | 0.833 | NA | NA | 343 | E | |
45 | 1 | 0 | 10 | 0.704 | NA | NA | E | 2 NRTI+1 ENH+1 INSTI | |
46 | 2 | 0.153 | 3 | 0.306 | 2 | 0.5 | N | ||
47 | 2 | 0.263 | 2 | 0.42 | 1 | 0 | 2755 | E | 1 NNRTI+1 PI+1 ENH+1 INSTI |
49 | 2 | 0.455 | 1 | 0 | 2 | 0.324 | 282 | E | 2 NRTI+1 ENH+1 INSTI |
50 | 1 | 0 | 2 | 0.344 | 3 | 0.624 | 576 | E | 2 NRTI+1 PI+1 ENH |
51 | 1 | 0 | 1 | 0 | 3 | 0.593 | E | 2 NRTI+1 PI+1 ENH+1 INSTI | |
52 | 2 | 0.439 | 1 | 0 | NA | NA | E | 2 NRTI+1 PI+1 ENH | |
54 | 3 | 0.583 | 1 | 0 | 2 | 0.491 | 412 | E | 2 NRTI+1 PI+1 ENH |
55 | 1 | 0 | 1 | 0 | 2 | 0.384 | E | 1 PI+1 ENH | |
56 | 12 | 0.392 | 3 | 0.641 | NA | NA | 1368 | E | 2 NRTI+1 ENH+1 INSTI |
57 | 1 | 0 | 1 | 0 | NA | NA | 12786 | E | 2 NRTI+1 ENH+1 INSTI |
58 | 1 | 0 | 3 | 0.59 | 4 | 0.659 | 1281 | E | 2 NRTI+1 ENH+1 INSTI |
59 | 3 | 0.572 | 1 | 0 | 4 | 0.705 | 581 | E | 2 NRTI+1 INSTI |
60 | 2 | 0.487 | 3 | 0.619 | 4 | 0.716 | E | 2 NRTI+1 PI+1 ENH | |
61 | 2 | 0.27 | 3 | 0.632 | 4 | 0.679 | 432 | E | |
63 | 3 | 0.612 | 6 | 0.708 | 1 | 0 | 57 | E | 2 NRTI+1 PI |
64 | 5 | 0.759 | 3 | 0.576 | 4 | 0.697 | E | ||
65 | 2 | 0.492 | 2 | 0.441 | 3 | 0.186 | E | 2 NRTI+1 PI+1 ENH | |
66 | 1 | 0 | 2 | 0.49 | 5 | 0.602 | 32 | E | 2 NRTI+1 ENH+1 INSTI |
67 | NA | NA | 2 | 0.45 | 5 | 0.767 | E | 2 NRTI+1 NNRTI | |
68 | 3 | 0.564 | 5 | 0.736 | 5 | 0.758 | E | 2 NRTI+1 NNRTI | |
69 | 1 | 0 | 4 | 0.543 | 7 | 0.777 | 48 | E | 2 NRTI+1 PI+1 ENH |
70 | 4 | 0.603 | 2 | 0.364 | 5 | 0.743 | 17 | N | |
71 | 1 | 0 | 4 | 0.72 | 6 | 0.812 | E | 1 NRTI+1 NNRTI+1 INSTI | |
72 | 2 | 0.209 | 3 | 0.614 | NA | NA | 353 | E | 2 NRTI+1 NNRTI |
73 | 1 | 0 | 3 | 0.66 | 2 | 0.414 | E | 2 NRTI+1 ENH+1 INSTI | |
74 | 1 | 0 | 5 | 0.779 | 4 | 0.037 | 1 | E | 2 NRTI+1 ENH+1 INSTI |
75 | 1 | 0 | 3 | 0.533 | 7 | 0.663 | E | 2 NRTI+1 PI+1 ENH | |
76 | 1 | 0 | 1 | 0 | 5 | 0.777 | 432 | E | 2 NRTI+1 INSTI |
77 | 4 | 0.613 | 4 | 0.658 | 6 | 0.768 | 113 | E | 2 NRTI+1 PI+1 ENH+1 INSTI |
78 | 2 | 0.183 | 3 | 0.608 | 5 | 0.664 | 113 | E | 2 NRTI+1 PI+1 ENH |
79 | 1 | 0 | 1 | 0 | 2 | 0.396 | E | 2 NRTI+1 INSTI | |
82 | 1 | 0 | NA | NA | NA | NA | N | ||
83 | 2 | 0.467 | NA | NA | NA | NA | 554 | E | 2 NRTI+1 NNRTI |
85 | 2 | 0.351 | 1 | 0 | 2 | 0.477 | 183 | E | 2 NRTI+1 INSTI |
86 | 2 | 0.433 | 1 | 0 | NA | NA | E | 2 NRTI+1 PI+1 ENH+1 INSTI | |
87 | 2 | 0.499 | NA | NA | NA | NA | E | 2 NRTI+1 ENH+1 INSTI | |
88 | 1 | 0 | NA | NA | 1 | 0 | 37 | N | |
90 | 3 | 0.534 | 2 | 0.498 | 3 | 0.54 | 8914 | E | 2 NRTI+1 PI+1 ENH+1 CCR5+1 INSTI |
91 | 1 | 0 | 2 | 0.003 | NA | NA | 117 | E | 2 NRTI+1 INSTI |
93 | 2 | 0.446 | 1 | 0 | NA | NA | 94 | E | 2 NRTI+1 ENH+1 INSTI |
94 | 1 | 0 | NA | NA | NA | NA | 145 | E | 2 NRTI+1 PI+1 ENH |
97 | 5 | 0.718 | 2 | 0.455 | 5 | 0.782 | E | 2 NRTI+1 INSTI | |
99 | 1 | 0 | NA | NA | 1 | 0 | 184 | E | 2 NRTI+1 ENH+1 INSTI |
Avg | 2 | 0.265 | 2 | 0.357 | 4 | 0.47 |
A haplotype diversity of 0 indicates no diversity because only a single haplotype was reconstructed by PredictHaplo for the sample. Amplicons that did not pass the filtering thresholds for a sample are indicated by “NA”. ARV exposure is reported at time that blood sample was taken. N: Naïve, E: Experienced, NRTI: Nucleoside reverse transcriptase inhibitors, NNRTI: Non-nucleoside reverse transcriptase inhibitors, ENH: enhancer elements, PI: Protease Inhibitor, INSTI: Integrase Strand Transfer Inhibitor, CCR5: Cysteine-Cysteine Chemokine Receptor 5.
Contributor Information
Keylie M. Gibson, Email: kmgibson@gwu.edu
the DC Cohort Executive Committee:
Thilakavathy Subramanian, Jeffery Binkley, Rob Taylor, Nabil Rayeed, Cheryl Akridge, Stacey Purinton, Jeff Naughton, Natella Rakhmanina, Larry D’Angelo, Michael Kharfen, Angela Wood, Michael Serlin, Princy Kumar, David Parenti, Alan Greenberg, Anne Monroe, Lindsey Powers Happ, Maria Jaurretche, James Peterson, Ronald D Wilcox, Sohail Rana, Michael A Horberg, Ricardo Fernández, Annick Hebou, Carl Dieffenbach, Henry Masur, Jose Bordon, Gebeyehu Teferi, Debra Benator, Maria Elena Ruiz, Deborah Goldstein, and David Hardy