FIG 5.

Genome-wide regulatory role of Ssr4 in B. bassiana. (A) Cluster analysis of differentially expressed genes (DEGs) in the transcriptomes generated from three 4-day-old SDAY cultures (three replicate cultures [R1, R2, and R3]) of Δssr4 and WT strains grown at the optimal regimen of 25°C and 12-h/12-h L/D cycle. (B) Distributions of log₂ ratios and FDR values for all genes significantly upregulated (UpR) (log₂ ratio ≥ 1), downregulated (DnR) (log₂ ratio ≤ −1), or not differentially regulated (NDR) (−1 < log₂ ratio < 1). (C and D) Counts of DEGs significantly enriched in eggNOG function classes (C) and KEGG pathways (D).