Figure 2.

Effect of CBD (4 µM) on reduced glutathione (GSH) level (A-I and A-II) and glutathione peroxidase (GSH-Px) activity as well as thioredoxin (Trx) level and thioredoxin reductase (Trx-R) activity in keratinocytes exposed to UVA (30 J/cm²) and UVB (60 mJ/cm²) radiation. Keratinocytes were obtained from healthy subjects (I) (n=15) and patients with psoriasis vulgaris (II) (n = 30). The mean values ± SD are presented with statistically significant differences: ^a-vs. control/psoriasis group; ^b-vs. group without CBD; ^x-psoriasis vs. control groups; p < 0.05.