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. 2020 Feb 28;25(5):1089. doi: 10.3390/molecules25051089

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of SAA on the expression levels of NF-κB and IL-1β in the aortic tissues of T2DM ZDF rats with AS. ZL and ZDF rats were sacrificed, and the aortic tissues were collected for gene and protein expression analysis. (A) The effects of SAA on p-NF-κB expression are shown. (B, C) The effects of SAA on IL-1β mRNA and protein expression are shown. The data are expressed as mean ± SEM (n = 6). * p < 0.05 vs. normal group; ^# p < 0.05 vs. model group. (D) Western blotting showed the p-NF-κB and IL-1β protein expression levels in each group.