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. 2020 Mar 31;25(7):1596. doi: 10.3390/molecules25071596

Table 2.

Summary of the morphometric and histological measurements in the rabbit iliac–femoral injury model.

No Coating KOS-only PXL-only KTO-PXL p Value
Morphometric Measurements
EEL, mm2 1.87 ± 0.33 1.64 ± 0.63 1.98 ± 0.48 1.39 ± 0.39 0.37
IEL, mm2 1.32 ± 0.24 1.15 ± 0.55 1.58 ± 0.24 0.99 ± 0.45 0.52
Lumen, mm2 1.18 ± 0.24 1.00 ± 0.55 1.32 ± 0.30 0.92 ± 0.43 0.58
Media, mm2 0.55 ± 0.10 0.50 ± 0.11 0.59 ± 0.18 0.40 ± 0.08 0.21
Neointimal area, mm2 0.15 ± 0.06 0.14 ± 0.04 0.11 ± 0.05 0.06 ± 0.02 0.085
Neointimal thickness, mm 0.10 ± 0.011 0.069 ± 0.022 0.066 ± 0.018 0.053 ± 0.003 0.005
Percent area stenosis, % 10.88 ± 4.52 9.99 ± 3.78 7.92 ± 3.84 6.80 ± 2.74 0.45
Histological Analysis
Injury 1.00 ± 0.41 0.75 ± 1.19 1.13 ± 1.32 0.50 ± 0.41 0.74
EC Score 0.25 ± 0.50 0.00 ± 0.00 0.25 ± 0.50 1.50 ± 0.58 0.013
Inflammation 0.25 ± 0.50 0.00 ± 0.00 0.50 ± 0.58 0.25 ± 0.50 0.86
SMC Loss 0.00 ± 0.00 0.00 ± 0.00 0.25 ± 0.50 1.00 ± 0.82 0.081

Abbreviations: EEL—external elastic lamina, IEL—internal elastic lamina, EC—endothelial cell, SMC—smooth muscle cell.