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. 2020 Apr 22:jiaa206. doi: 10.1093/infdis/jiaa206

Transmission potential of asymptomatic and paucisymptomatic SARS-CoV-2 infections: a three-family cluster study in China

Xiao-Lin Jiang 1,3, Xiao-Li Zhang 2,3, Xiang-Na Zhao 3,3, Cun-Bao Li 4, Jie Lei 1, Zeng-Qiang Kou 1, Wen-Kui Sun 1, Yang Hang 1, Feng Gao 5, Sheng-Xiang Ji 2, Can-Fang Lin 4, Bo Pang 1, Ming-Xiao Yao 1, Benjamin D Anderson 6, Guo-Lin Wang 7, Lin Yao 7, Li-Jun Duan 7, Dian-Ming Kang 1,#,, Mai-Juan Ma 7,#,
PMCID: PMC7188140  PMID: 32319519

Abstract

Data concerning the transmission of SARS-CoV-2 in asymptomatic and paucisymptomatic patients are lacking. We report a three-family cluster of infections involving asymptomatic and paucisymptomatic transmission. Eight (53%) of 15 members from three families were confirmed with SARS-CoV-2 infection. Of eight patients, three were asymptomatic and one was paucisymptomatic. An asymptomatic mother transmitted the virus to her son, and a paucisymptomatic father transmitted the virus to his three-month-old daughter. SARS-CoV-2 was detected in the environment of one household. The complete genomes of SARS-CoV-2 from the patients were >99.9% identical and were clustered with other SARS-CoV-2 sequences reported from China and other countries.

Keywords: SARS-CoV-2, COVID-2019, asymptomatic, paucisymptomatic, transmission


Articles from The Journal of Infectious Diseases are provided here courtesy of Oxford University Press

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