Table 1.
Drug | Trade name | Mode of action | Treatment stage |
---|---|---|---|
Donepezil | Aricept | Acetylcholinesterase inhibitora | All stages |
Galantamine | Razadyne | Acetylcholinesterase inhibitora | Mild to moderate |
Rivastigmine | Exelon | Acetylcholinesterase inhibitora | Mild to moderate |
Memantine | Namenda | NMDA receptor antagonist | Mild |
Donepezil + memantine | Namzaric | Acetylcholinesterase inhibitor + NMDA receptor antagonistb | Moderate to severe |
aMay delay or slow worsening of symptoms. Effectiveness varies from person to person
bEffective in individuals with moderate to severe AD who are taking a cholinesterase inhibitor might benefit by also taking memantine