Figure 2.
Mechanical transfection platform deforms cell membrane. A. Cell squeezing device. Reproduced with permission from Proceedings of the National Academy of Sciences USA 86 Copyright 2013. B. Workflow schematic and SEM image of sharp angle constriction made of silicon, scale bar: 30 µm. Reproduced with permission from Oxford University Press 87 Copyright 2017. C. Image of cells being deformed when passing through the constriction. Reproduced with permission from American Association for the Advancement of Science 88 CC BY-NC 4.0. D. Setup of TRansmembrane Internalization Assisted by Membrane Filtration (TRIAMF) method for CRISPR transfection. Reproduced with permission from Springer Nature 89 CC BY 4.0.