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. 2020 Mar 24;14(4):5148. doi: 10.1021/acsnano.0c01699

Correction to Resolving Chemical Modifications to a Single Amino Acid within a Peptide Using a Biological Nanopore

Laura Restrepo-Pérez, Gang Huang, Peggy R Bohländer, Nathalie Worp, Rienk Eelkema, Giovanni Maglia, Chirlmin Joo, Cees Dekker
PMCID: PMC7199206  PMID: 32207923

In Figure 5c, we reported the correlation between dwell times and electrical charges of tags. We did not account for the sign of some of the tags correctly, leading to an error that we would like to amend. In the published Figure 5c, the value of the parameter charge × P for the labels Alexa 633 and 3PolyA should have had a negative value. Below, we provide a corrected figure and figure legend. We note that this correction does not in any way affect the conclusions of the article.

Figure 5.

Figure 5

Scatter plots of the peptide labeled with (a) His6 and (b) Alexa633. Faster translocation times are observed in peptides labeled with His6 compared to Alexa633. (c) Plot of dwell time vs net charge × P, where P = M × w/L (see Figure 4). A correlation (R2 = 0.85) is observed between these parameters. The errors in the x-axis for fluorescein, His6, and PEG11 represent the range of values that the parameter can take due to the possible charged states of the molecules.

For completeness, we would also like to add some additional citations: (13).

References

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