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. Author manuscript; available in PMC: 2021 May 5.
Published in final edited form as: Circulation. 2020 May 4;141(18):1431–1433. doi: 10.1161/CIRCULATIONAHA.119.044996

Table 1.

Criteria for the Definition of Acute Myocardial Infarction versus Acute Myocardial Injury

Acute Myocardial Infarction* Acute Myocardial Injury*
Mechanism Coronary Occlusion Extra-coronary
Common Examples Coronary thrombosis
Coronary vasospasm
Coronary embolism
Coronary artery dissection
In-stent thrombosis		 Supply and demand mismatch
Atrial fibrillation with RVR
Pulmonary Embolism
Shock
Sepsis
Takotsubo CMP
Acute anemia/hemorrhage
Treatment Goal Restoring coronary blood flow Identifying and treating the underlying cause
*

For patients who meet criteria for both conditions (e.g. an acute extra-coronary event triggering acute myocardial ischemia in the setting of critical obstructive coronary artery disease), it will be at the discretion of the clinical team to decide whether acute myocardial infarction or acute myocardial injury is more appropriate.