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. 2020 May 6;15(5):e0233051. doi: 10.1371/journal.pone.0233051

Correction: Performance of risk prediction scores for cardiovascular mortality in older persons: External validation of the SCORE OP and appraisal

Marco Piccininni, Jessica L Rohmann, Dörte Huscher, Nina Mielke, Natalie Ebert, Giancarlo Logroscino, Elke Schäffner, Tobias Kurth
PMCID: PMC7202620  PMID: 32374778

There are errors in the layout of Table 2. Please see the correct Table 2 here.

Table 2. Risk scores: measures of validity.

Risk scorea Predicted number of fatal cardiovascular events Actual number of fatal cardiovascular eventsb Predicted/ Actual ratio Nam-D’Agostino chi-square
(p-value)
C-indexc (95% CI)
SCORE OP
high-risk regions
0.79
(0.75 to 0.83)
SCORE OP-H 5y 302 142 2.13 139.16
(p<0.001)
SCORE OP-H 677 399 1.70 327.9
(p<0.001)
SCORE OP
low-risk regions
0.80
(0.75 to 0.83)
SCORE OP-L 5y 215 142 1.51 39.68
(p<0.001)
SCORE OP-L 519 397 1.31 76.29
(p<0.001)
SCORE-H 372 382 0.97 29.68
(p = 0.001)
0.72
(0.67 to 0.76)
SCORE-L 258 384 0.67 117.63
(p<0.001)
0.72
(0.67 to 0.77)

aSCORE OP[22] and SCORE[13] systems have been previously described elsewhere. H and L indicate high- and low- cardiovascular risk regions. 5y indicates 5-year risk equations. All other scores listed are 10-year versions.

bWeibull regression model projections beyond the observed follow-up are reported for 10-year risk scores, leading to small differences in the number of actual events. 5-year risk scores use observed Berlin Initiative Study data only using the Kaplan-Meier estimator.

cRisk score discrimination capability was assessed using the entire observed follow-up data.

Reference

  • 1.Piccininni M, Rohmann JL, Huscher D, Mielke N, Ebert N, Logroscino G, et al. (2020) Performance of risk prediction scores for cardiovascular mortality in older persons: External validation of the SCORE OP and appraisal. PLoS ONE 15(4): e0231097 10.1371/journal.pone.0231097 [DOI] [PMC free article] [PubMed] [Google Scholar]

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