There are errors in the layout of Table 2. Please see the correct Table 2 here.
Table 2. Risk scores: measures of validity.
| Risk scorea | Predicted number of fatal cardiovascular events | Actual number of fatal cardiovascular eventsb | Predicted/ Actual ratio | Nam-D’Agostino chi-square (p-value) |
C-indexc (95% CI) |
|---|---|---|---|---|---|
|
SCORE OP high-risk regions |
0.79 (0.75 to 0.83) |
||||
| SCORE OP-H 5y | 302 | 142 | 2.13 | 139.16 (p<0.001) |
|
| SCORE OP-H | 677 | 399 | 1.70 | 327.9 (p<0.001) |
|
|
SCORE OP low-risk regions |
0.80 (0.75 to 0.83) |
||||
| SCORE OP-L 5y | 215 | 142 | 1.51 | 39.68 (p<0.001) |
|
| SCORE OP-L | 519 | 397 | 1.31 | 76.29 (p<0.001) |
|
| SCORE-H | 372 | 382 | 0.97 | 29.68 (p = 0.001) |
0.72 (0.67 to 0.76) |
| SCORE-L | 258 | 384 | 0.67 | 117.63 (p<0.001) |
0.72 (0.67 to 0.77) |
aSCORE OP[22] and SCORE[13] systems have been previously described elsewhere. H and L indicate high- and low- cardiovascular risk regions. 5y indicates 5-year risk equations. All other scores listed are 10-year versions.
bWeibull regression model projections beyond the observed follow-up are reported for 10-year risk scores, leading to small differences in the number of actual events. 5-year risk scores use observed Berlin Initiative Study data only using the Kaplan-Meier estimator.
cRisk score discrimination capability was assessed using the entire observed follow-up data.
Reference
- 1.Piccininni M, Rohmann JL, Huscher D, Mielke N, Ebert N, Logroscino G, et al. (2020) Performance of risk prediction scores for cardiovascular mortality in older persons: External validation of the SCORE OP and appraisal. PLoS ONE 15(4): e0231097 10.1371/journal.pone.0231097 [DOI] [PMC free article] [PubMed] [Google Scholar]
