Figure 3. Conformational Change of Lassa NP during 4 μs simulation.
Overlay of initial and final structures of the 4 μs Anton simulation. The initial structure is consistent with the trimeric crystal structure (PDBID 3MWP.B) and is colored in cyan (N-term) and brown (C-term). The final structure is colored in blue (N-term) and purple (C-term). Structures are shown from front (0°), side (90°) and back (180°) views. Structures were aligned along the α5 helix.