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(a) Cumulative release of insulin from the different tablets immersed 2 h at pH 1.2 and subsequently at pH 7.4. Data shown as mean ± SE (n=3), Significant difference express **p<0.01, ****p<0.0001, One‐way ANOVA and Fisher Test; (b–d) MS characterization of the released insulin or the fragments of insulin at different time periods in correlation with their respective proportion.
