Figure 5.

In vitro assay based on the presence (no starvation) or absence (starvation) of insulin in the culture media of HCEC cells prior to the incubation of different treatments: commercial human insulin at the concentration 10 or 15 μg mL⁻¹, insulin confined in pure DMSNs or thiol‐functionalized DMSN‐SH at the concentration equivalent to 15 μg mL⁻¹ of insulin. One‐way ANOVA and Fisher Test expressed significant difference by *p<0.05, **p<0.01, ***p<0.001.