Table 2. Overall distribution of the functional responses elicited at the cortical level according to a matching analysis with the JHU Atlas (cortical and cortical plus white matter ROIs).
For each functional category, the percentage of DES-defined positive cortical sites that overlap with a given ROI is presented. For example, 32.4% of cortical sites where anomia was elicited with direct electrical stimulation overlapped with the JHU Atlas-defined left superior temporal gyrus, and 1.3% overlapped with the JHU Atlas-defined superior temporal gyrus white matter. MFG: middle frontal gyrus; MTG: middle temporal gyrus; IFG: inferior frontal gyrus; ITG: inferior temporal gyrus; PreCG: pre-central gyrus; PostCG: post-central gyrus; SFG: superior frontal gyrus; SMG: supra marginal gyrus; SPL: superior parietal lobule; STG: superior temporal gyrus; WM: white matter.
| Left hemisphere | Right hemisphere | |
|---|---|---|
| Alexia | MTG (90.3%), ITG (7.2%), MTG WM (2.4%) | - |
| Anomia | STG (32.4%), ITG (17.1%), MTG (17.1%), MFG (10.2%), SMG (4.7%), IFG WM (2.3%), STG WM (1.3%) | STG (2.4%) |
| Comprehension | MTG (20.3%), MFG (8.9%), STG (7%), | MFG (24.9%), IFG (16.5%), STG (6.3%), MTG (5.3%), MFG WM (2.3%), IFG WM (1.6%), SMG (1.3%) |
| Eye Movement Control | - | PreCG WM (65.9%), PreCG (27.1%), PostCG (7.1%) |
| Mentalizing | - | MFG (62.1%), IFG (22%), SFG (6.6%), MFG WM (6.5%), IFG WM (2.7%) |
| Motor | PreCG (18.2%), PostCG (8.3%), MFG (6.7%), PreCG WM (2.5%), SFG (1.9%), IFG (1.1%) | PreCG (22.7%), PostCG (12.3%), SFG (5.2%), MFG (4.9%), PreCG WM (4.1%), IFG (2.1%), STG (1.8%), PostCG WM (1.7%), SPL (1.2%) |
| Motor Control | MFG (9.9%), SFG (8.8%), PreCG (7%), PostCG (4.4%), SMG (2.3%), PostCG WM (1.7%), PreCG WM (1.5%), IFG (1%) | PreCG (26.4%), MFG (9.1%), STG (8.3%), SFG (4.1%), PreCG WM (4%), IFG (4%), PostCG (2.7%), STG WM (1.1%) |
| Phonological | SMG (31.4%), MFG (22.9%), MTG (21.4%), IFG (12.6%), SMG WM (3.6%), MFG WM (2.7%), STG (2%), ITG (1.5%) | - |
| Semantic | MFG (24.2%), STG (22.5%), IFG (21.6%), MTG (20.1%), IFG WM (3.2%), MFG WM (2.6%), STG WM (1.5%), PostCG (1%) | STG (1.5%) |
| Somatosensory | PostCG (26%), PreCG (5.3%), PostCG WM (4.6%), SMG (3.4%), SPL (1.4%) | PostCG (32%), PreCG (6.1%), SPL (5.6%), PostCG WM (5.4%), SMG (5.4%) |
| Spatial perception | SMG (5.9%) | SMG (40.9%), STG (25.1%), MTG (8.7%), SMG WM (5.9%), MFG (4.1%), STG WM (3.2%), SPL (1.8%), MFG WM (1.5%) |
| Speech Output | PreCG (27.3%), IFG (11.1%), PostCG (10.6%), PreCG WM (4.3%), SMG (4%), STG (4%), MTG (3.9%), IFG WM (1.8%) | PreCG (10.4%), IFG (5.2%), STG (5%), PostCG (3.1%), PreCG WM (2%), SMG (1.8%), MFG (1.8%), IFG WM (1%) |
| Speech Articulation | PostCG (19.9%), MFG (9.1%), PreCG (7.4%), IFG (7.2%), SMG (4.5%), STG (3.7%), PostCG WM (1.5%), IFG WM (1.3%) | PreCG (14.8%), IFG (11.2%), MFG (5.4%), PostCG (5.4%), PreCG WM (3.4%), STG (1.7%) |