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. Author manuscript; available in PMC: 2021 May 12.

Published in final edited form as: Circulation. 2020 Apr 1;141(19):1541–1553. doi: 10.1161/CIRCULATIONAHA.119.045010

Figure 3. — Number needed to treat with low-dose aspirin during 5 years to prevent one CVD event and number needed to cause a major bleeding event by baseline CAC score, overall (Panel A) and by sex (Panel B).

Results presented as number of persons. Follow-up was censored at 5 years. Red horizontal lines represent NNH thresholds. Participants with CAC ≥400 had zero bleeding events and the NNH could not be computed. The exploratory NNT for participants with CAC ≥400 was computed only overall.

Abbreviations: CAC = coronary artery calcium; CVD = cardiovascular disease; NNH = number needed to harm; NNT = number needed to treat

Figure 3. — Number needed to treat with low-dose aspirin during 5 years to prevent one CVD event and number needed to cause a major bleeding event by baseline CAC score, overall (Panel A) and by sex (Panel B).

Results presented as number of persons. Follow-up was censored at 5 years. Red horizontal lines represent NNH thresholds. Participants with CAC ≥400 had zero bleeding events and the NNH could not be computed. The exploratory NNT for participants with CAC ≥400 was computed only overall.

Abbreviations: CAC = coronary artery calcium; CVD = cardiovascular disease; NNH = number needed to harm; NNT = number needed to treat