Table 3.
Subtype | N | Ubiquitin (ng/mL) Median (IQR) | NfL (pg/mL) Median (IQR) | t-tau (pg/mL) Median (IQR) | YKL-40 (ng/mL) Median (IQR) |
---|---|---|---|---|---|
sCJD MM(V)1 | 33 | 136.0 (94.6–199.0) | 5250 (3689–6800) | 6506 (2939–9223) | 257 (168–353) |
sCJD VV2 | 18 | 261.0 (186.3–305.3) | 12525 (10750–15963) | 8358 (4957–14825) | 533 (300–764) |
sCJD MV2K | 15 | 71.4 (62.1–118.0) | 8250 (3665–11750) | 2293 (1433–3088) | 336 (199–486) |
sCJD MM2C | 4 | 79 (40.7–188.0) | 8525 (3112–13763) | 2136 (907–6893) | 321 (185–976) |
sCJD VV1 | 1 | 94.7 | 15900 | 3790 | 455 |
VPSPr | 1 | 65.3 | 1606 | 1273 | 341 |
gCJD E200K | 4 | 79.0 (40.7–188.0) | 8525 (3112–13763) | 2137 (907–6893) | 321 (185–976) |
gCJD V210I | 4 | 186.5 (159.0–283.8) | 7813 (2929–12375) | 8518 (6069–14125) | 409 (165–474) |
FFI (D178N) | 3 | 18.8, 29.0, 28.1 | 11881, 5150, 3536 | 120, 288, 190 | 253, 146, 165 |
GSS (P102L) | 1 | 54.3 | 2611 | 5664 | 450 |