Morphological and functional echocardiographic parameters in controls and men and women with AS who were older than 50 years of age. (A) LVMI, LV mass index; (B) LVEDdI, LV end-diastolic diameter index; (C) rPWT, relative posterior wall thickness; (D) LVEF, LV ejection fraction; (E) MAPSE, mitral annular plane systolic excursion; (F) E/e′, the ratio of peak early transmitral flow velocity to peak early myocardial tissue velocity (e′). Whiskers represent the 10th–90th percentiles. ** p < 0.01, *** p < 0.001 (two-way ANOVA followed by Bonferroni post hoc test). Control patients: men = 11, women = 15; AS patients: men = 45, women = 50. For MAPSE, control: men = 8, women = 10; AS patients: men = 42, women = 45. For E/e’, control: men = 5, women = 5; AS patients: men = 24 and women = 38.