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. 2020 Apr 7;9(4):905. doi: 10.3390/cells9040905

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Evaluation of acellular capillary formation and superoxide anion generation in T1D mice. Representative images of trypsin-digested retinal vascular preparations from 4-month old control mice and 4-month old mice with 2-month duration of T1D (A) The arrow indicates an acellular capillary. Quantitative measurement of acellular capillaries was significantly increased in diabetic eyes (n = 6). (B) STZ-induced diabetic retina showed >1.5 fold increase in superoxide anion levels, p < 0.01 (C) The errors bars represent SEM.